543 XNAS Volume
XNAS 18 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Carrie L. Bourdow | Director, Acting CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 285 | 25,234 (0%) | 0% | 1.5 | 419 | Common Stock |
| Carrie L. Bourdow | Director, Acting CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 1,055 | 23,894 (0%) | 0% | 1.5 | 1,551 | Common Stock |
| Carrie L. Bourdow | Director, Acting CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 285 | 24,949 (0%) | 0% | 1.5 | 419 | Common Stock |
| Carrie L. Bourdow | Director, Acting CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.46 per share. | 08 Oct 2024 | 54 | 25,662 (0%) | 0% | 1.5 | 79 | Common Stock |
| Carrie L. Bourdow | Director, Acting CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 143 | 25,519 (0%) | 0% | 1.5 | 210 | Common Stock |
| Mark A. Demitrack | Acting CMO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 144 | 11,895 (0%) | 0% | 1.5 | 212 | Common Stock |
| Mark A. Demitrack | Acting CMO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 45 | 12,183 (0%) | 0% | 1.5 | 66 | Common Stock |
| Mark A. Demitrack | Acting CMO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.45 per share. | 08 Oct 2024 | 20 | 12,228 (0%) | 0% | 1.5 | 29 | Common Stock |
| Mark A. Demitrack | Acting CMO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 532 | 11,363 (0%) | 0% | 1.5 | 782 | Common Stock |
| Mark A. Demitrack | Acting CMO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 144 | 12,039 (0%) | 0% | 1.5 | 212 | Common Stock |
| Barry Shin | Acting COO and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 130 | 12,031 (0%) | 0% | 1.5 | 191 | Common Stock |
| Barry Shin | Acting COO and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 17 | 12,332 (0%) | 0% | 1.5 | 25 | Common Stock |
| Barry Shin | Acting COO and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.46 per share. | 08 Oct 2024 | 41 | 12,291 (0%) | 0% | 1.5 | 60 | Common Stock |
| Barry Shin | Acting COO and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 130 | 12,161 (0%) | 0% | 1.5 | 191 | Common Stock |
| Barry Shin | Acting COO and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.47 per share. | 08 Oct 2024 | 488 | 11,543 (0%) | 0% | 1.5 | 717 | Common Stock |
| Robert T. Yoder | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.95 per share. | 14 Sep 2024 | 487 | 5,868 (0%) | 0% | 6.0 | 2,898 | Common Stock |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.00 per share. | 14 Sep 2024 | 3 | 12,349 (0%) | 0% | 6 | 18 | Common Stock |
| Mark H.N. Corrigan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Marvin H. Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Yoder T. Robert | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 92,500 | 135,806 (0%) | 0% | 0.6 | 56,425 | Common Stock |
| T. Robert Yoder | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 25,000 | 160,806 (0%) | 0% | 0.6 | 15,250 | Common Stock |
| Robert T. Yoder | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.61 per share. | 14 Dec 2023 | 1,929 | 158,877 (0%) | 0% | 0.6 | 1,177 | Common Stock |
| Barry Shin | SVP, CFO | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 50,000 | 312,437 (0%) | 0% | 0.6 | 30,500 | Common Stock |
| M. Drake Patricia | SVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.61 per share. | 14 Dec 2023 | 1,835 | 107,078 (0%) | 0% | 0.6 | 1,119 | Common Stock |
| Bourdow Carrie L. | President & CEO | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 370,000 | 550,046 (0%) | 0% | 0.6 | 225,700 | Common Stock |
| Shin Barry | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.61 per share. | 14 Dec 2023 | 3,616 | 308,821 (0%) | 0% | 0.6 | 2,206 | Common Stock |
| Carrie Bourdow L. | President & CEO | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 100,000 | 650,046 (0%) | 0% | 0.6 | 61,000 | Common Stock |
| Barry Shin | SVP, CFO | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 185,000 | 262,437 (0%) | 0% | 0.6 | 112,850 | Common Stock |
| Bourdow Carrie L. | President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.61 per share. | 14 Dec 2023 | 7,123 | 642,923 (0%) | 0% | 0.6 | 4,345 | Common Stock |
| M. Drake Patricia | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 50,000 | 83,913 (0%) | 0% | 0.6 | 30,500 | Common Stock |
| Drake M. Patricia | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 14 Dec 2023 | 25,000 | 108,913 (0%) | 0% | 0.6 | 15,250 | Common Stock |
| Mark Demitrack A. | SVP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 497 | 79,531 (0%) | 0% | 0.6 | 293 | Common Stock |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 407 | 82,066 (0%) | 0% | 0.6 | 240 | Common Stock |
| A. Mark Demitrack | SVP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.61 per share. | 02 Dec 2023 | 3,593 | 306,224 (0%) | 0% | 0.6 | 2,192 | Common Stock |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 1,023 | 81,043 (0%) | 0% | 0.6 | 604 | Common Stock |
| A. Mark Demitrack | SVP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 1,121 | 78,410 (0%) | 0% | 0.6 | 661 | Common Stock |
| Patricia M. Drake | SVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 1,835 | 33,913 (0%) | 0% | 0.6 | 1,083 | Common Stock |
| Mark A. Demitrack | SVP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 02 Dec 2023 | 185,000 | 259,817 (0%) | 0% | 0.6 | 112,850 | Common Stock |
| Yoder T. Robert | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 436 | 45,976 (0%) | 0% | 0.6 | 257 | Common Stock |
| Yoder T. Robert | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 741 | 45,235 (0%) | 0% | 0.6 | 437 | Common Stock |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 3,606 | 77,437 (0%) | 0% | 0.6 | 2,128 | Common Stock |
| L. Carrie Bourdow | President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 1,343 | 190,731 (0%) | 0% | 0.6 | 792 | Common Stock |
| M. Patricia Drake | SVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 294 | 35,748 (0%) | 0% | 0.6 | 173 | Common Stock |
| Carrie L. Bourdow | President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 3,562 | 187,169 (0%) | 0% | 0.6 | 2,102 | Common Stock |
| T. Robert Yoder | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 1,929 | 43,306 (0%) | 0% | 0.6 | 1,138 | Common Stock |
| Mark Demitrack A. | SVP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 3,593 | 74,817 (0%) | 0% | 0.6 | 2,120 | Common Stock |
| L. Bourdow Carrie | President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.59 per share. | 02 Dec 2023 | 7,123 | 180,046 (0%) | 0% | 0.6 | 4,203 | Common Stock |
| Mark Demitrack A. | SVP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.61 per share. | 02 Dec 2023 | 50,000 | 309,817 (0%) | 0% | 0.6 | 30,500 | Common Stock |
| Mark H.N. Corrigan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jul 2023 | 34,250 | 34,250 | - | - | Stock Option (Right to Buy) | |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.84 per share. | 26 Jun 2023 | 722 | 82,545 (0%) | 0% | 0.8 | 606 | Common Stock |
| Leon O. Moulder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Marvin H. Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 13,700 | 13,700 | - | - | Stock Option (Right to Buy) | |
| Carrie L. Bourdow | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 100,000 | 192,074 (0%) | 0% | 0 | Common Stock | |
| Mark A. Demitrack | SVP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 50,000 | 80,028 (0%) | 0% | 0 | Common Stock | |
| Robert T. Yoder | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 25,000 | 46,412 (0%) | 0% | 0 | Common Stock | |
| Barry Shin | SVP, CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 50,000 | 83,267 (0%) | 0% | 0 | Common Stock | |
| Patricia M. Drake | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 25,000 | 36,674 (0%) | 0% | 0 | Common Stock | |
| Carrie L. Bourdow | President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.55 per share. | 17 Dec 2022 | 1,342 | 92,074 (0%) | 0% | 1.5 | 2,080 | Common Stock |
| Mark A. Demitrack | SVP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.55 per share. | 17 Dec 2022 | 497 | 30,028 (0%) | 0% | 1.5 | 770 | Common Stock |
| Robert T. Yoder | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.55 per share. | 17 Dec 2022 | 443 | 21,412 (0%) | 0% | 1.6 | 687 | Common Stock |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.55 per share. | 17 Dec 2022 | 413 | 33,267 (0%) | 0% | 1.5 | 640 | Common Stock |
| Carrie L. Bourdow | Director, President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.42 per share. | 02 Dec 2022 | 3,560 | 93,416 (0%) | 0% | 3.4 | 12,175 | Common Stock |
| Mark A. Demitrack | SVP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.42 per share. | 02 Dec 2022 | 1,121 | 30,525 (0%) | 0% | 3.4 | 3,834 | Common Stock |
| Robert T. Yoder | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.42 per share. | 02 Dec 2022 | 753 | 21,855 (0%) | 0% | 3.4 | 2,575 | Common Stock |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.42 per share. | 02 Dec 2022 | 1,170 | 33,680 (0%) | 0% | 3.4 | 4,001 | Common Stock |
| Patricia M. Drake | SVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.42 per share. | 02 Dec 2022 | 294 | 11,674 (0%) | 0% | 3.4 | 1,005 | Common Stock |
| Patricia M. Drake | SVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.47 per share. | 10 Nov 2022 | 632 | 11,968 (0%) | 0% | 2.5 | 1,561 | Common Stock |
| Barry Shin | SVP, CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.21 per share. | 14 Sep 2022 | 1,792 | 871,264 (0%) | 0% | 0.2 | 369 | Common Stock |
| Barry Shin | SVP, CFO | Sale of securities on an exchange or to another person at price $ 0.41 per share. | 28 Jun 2022 | 31,785 | 873,056 (0%) | 0% | 0.4 | 13,032 | Common Stock |
| Leon O. Moulder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Marvin Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Carrie L. Bourdow | Director, President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.65 per share. | 06 Dec 2021 | 93,561 | 2,457,949 (2%) | 0% | 0.7 | 60,815 | Common Stock |
| Mark A. Demitrack | SVP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.65 per share. | 06 Dec 2021 | 30,601 | 803,580 (0%) | 0% | 0.7 | 19,891 | Common Stock |
| Robert T. Yoder | SVP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.65 per share. | 06 Dec 2021 | 22,950 | 574,916 (0%) | 0% | 0.7 | 14,918 | Common Stock |
| Barry Shin | SVP, CFO & CCO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.65 per share. | 06 Dec 2021 | 34,408 | 919,057 (0%) | 0% | 0.6 | 22,365 | Common Stock |
| Carrie L. Bourdow | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2021 | 1,250,000 | 2,551,510 (2%) | 1% | 0 | Common Stock | |
| Mark A. Demitrack | SVP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2021 | 390,000 | 834,181 (0%) | 0% | 0 | Common Stock | |
| Robert T. Yoder | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2021 | 240,000 | 597,866 (0%) | 0% | 0 | Common Stock | |
| Barry Shin | SVP, CFO & CCO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2021 | 390,000 | 953,465 (1%) | 0% | 0 | Common Stock | |
| Barry Shin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Sep 2021 | 27,500 | 563,465 (0%) | 0% | 0 | Common Stock | |
| Barry Shin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Sep 2021 | 41,250 | 41,250 | - | - | Stock Option (Right to Buy) | |
| Carrie L. Bourdow | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 1.79 per share. | 28 Jun 2021 | 56,200 | 1,301,510 (1%) | 0% | 1.8 | 100,542 | Common Stock |
| Barry Shin | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.96 per share. | 25 Jun 2021 | 24,635 | 535,965 (0%) | 0% | 2.0 | 48,285 | Common Stock |
| Leon O. Moulder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2021 | 68,577 | 68,577 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2021 | 68,577 | 68,577 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2021 | 68,577 | 68,577 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2021 | 68,577 | 68,577 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2021 | 68,577 | 68,577 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2021 | 68,577 | 68,577 | - | - | Stock Option (Right to Buy) | |
| Marvin Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Mar 2021 | 118,880 | 118,880 | - | - | Stock Option (Right to Buy) | |
| Scott Applebaum | CLCO; SVP, Regulatory Affairs | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.85 per share. | 10 Feb 2021 | 21,178 | 344,022 (0%) | 0% | 2.8 | 60,357 | Common Stock |
| Scott Applebaum | CLCO; SVP, Regulatory Affairs | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 172,750 | 172,750 | - | - | Stock Option (Right to Buy) | |
| Scott Applebaum | CLCO; SVP, Regulatory Affairs | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 115,200 | 365,200 (0%) | 0% | 0 | Common Stock | |
| Carrie L. Bourdow | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 706,650 | 706,650 | - | - | Stock Option (Right to Buy) | |
| Carrie L. Bourdow | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 471,100 | 1,264,060 (1%) | 0% | 0 | Common Stock | |
| Mark A. Demitrack | Sr. VP & Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 259,100 | 259,100 | - | - | Stock Option (Right to Buy) | |
| Mark A. Demitrack | Sr. VP & Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 172,700 | 444,181 (0%) | 0% | 0 | Common Stock | |
| Robert T. Yoder | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 212,000 | 212,000 | - | - | Stock Option (Right to Buy) | |
| Robert T. Yoder | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 141,300 | 357,866 (0%) | 0% | 0 | Common Stock | |
| Barry Shin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 235,550 | 235,550 | - | - | Stock Option (Right to Buy) | |
| Barry Shin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2020 | 157,000 | 560,600 (0%) | 0% | 0 | Common Stock | |
| Carrie L. Bourdow | Director, President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.27 per share. | 07 Dec 2020 | 151,684 | 1,245,310 (1%) | 0% | 2.3 | 344,323 | Common Stock |
| Mark A. Demitrack | Sr. VP & Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.27 per share. | 07 Dec 2020 | 48,557 | 271,481 (0%) | 0% | 2.3 | 110,224 | Common Stock |
| Robert T. Yoder | Sr VP Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.27 per share. | 07 Dec 2020 | 36,688 | 216,566 (0%) | 0% | 2.3 | 83,282 | Common Stock |
| Barry Shin | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.27 per share. | 07 Dec 2020 | 41,861 | 403,600 (0%) | 0% | 2.3 | 95,024 | Common Stock |
| Robert T. Yoder | Sr. VP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2020 | 59,000 | 59,000 | - | - | Stock Option (Right to Buy) | |
| Barry Shin | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.72 per share. | 25 Jun 2020 | 23,539 | 445,461 (0%) | 0% | 1.7 | 40,487 | Common Stock |
| Leon O. Moulder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Maxine Gowen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Julie H. McHugh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2020 | 64,103 | 64,103 | - | - | Stock Option (Right to Buy) | |
| Scott Applebaum | CLCO; SVP Regulatory Affairs | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2020 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Scott Applebaum | CLCO; SVP Regulatory Affairs | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2020 | 250,000 | 250,000 (0%) | 0% | 0 | Common Stock | |
| Carrie L. Bourdow | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 657,000 | 925,894 (0%) | 0% | 0 | Common Stock | |
| Mark A. Demitrack | Sr. VP & Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 213,000 | 320,038 (0%) | 0% | 0 | Common Stock | |
| Robert T. Yoder | Sr. VP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 167,000 | 253,254 (0%) | 0% | 0 | Common Stock | |
| Barry Shin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 194,000 | 469,000 (0%) | 0% | 0 | Common Stock | |
| Carrie L. Bourdow | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.69 per share. | 02 Dec 2019 | 17,804 | 268,894 (0%) | 0% | 0.7 | 12,265 | Common Stock |
| Mark A. Demitrack | Sr. VP & Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.69 per share. | 02 Dec 2019 | 8,982 | 107,038 (0%) | 0% | 0.7 | 6,188 | Common Stock |
| Robert T. Yoder | Sr. VP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.69 per share. | 02 Dec 2019 | 6,874 | 86,254 (0%) | 0% | 0.7 | 4,735 | Common Stock |
| Carrie L. Bourdow | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Sep 2019 | 250,000 | 250,000 | - | - | Stock Option (Right to Buy) | |
| Mark A. Demitrack | Sr. VP & Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Sep 2019 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Robert T. Yoder | Sr. VP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Sep 2019 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Barry Shin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2019 | 275,000 | 275,000 (0%) | 0% | 0 | Common Stock | |
| Barry Shin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2019 | 275,000 | 275,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.17 per share. | 03 Jun 2019 | 17,802 | 286,698 (0%) | 0% | 1.2 | 20,828 | Common Stock |
| Mark A. Demitrack | Sr VP & Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.17 per share. | 03 Jun 2019 | 8,980 | 116,020 (0%) | 0% | 1.2 | 10,507 | Common Stock |
| Robert T. Yoder | Sr. VP, Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.17 per share. | 03 Jun 2019 | 6,872 | 93,128 (0%) | 0% | 1.2 | 8,040 | Common Stock |
| John P. Hamill | VP Fin,Princ Fin&Acct Officer | Purchase of securities on an exchange or from another person at price $ 1.16 per share. | 31 May 2019 | 7,500 | 87,750 (0%) | 0% | 1.2 | 8,700 | Common Stock |
| John P. Hamill | VP Fin,Princ Fin&Acct Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.17 per share. | 31 May 2019 | 5,516 | 82,234 (0%) | 0% | 1.2 | 6,454 | Common Stock |
| Leon O. Moulder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Maxine Gowen | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Julie H. McHugh | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Leon O. Moulder | None | Purchase of securities on an exchange or from another person at price $ 1.02 per share. | 01 Feb 2019 | 100,000 | 100,000 (0%) | 0% | 1.0 | 102,000 | Common Stock |
| Maxine Gowen | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 1.02 per share. | 01 Feb 2019 | 50,000 | 54,000 (0%) | 0% | 1.0 | 51,000 | Common Stock |
| Carrie L. Bourdow | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 1.02 per share. | 01 Feb 2019 | 50,000 | 304,500 (0%) | 0% | 1.0 | 51,000 | Common Stock |
| John P. Hamill | VP Fin,Princ Fin&Acct Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2018 | 80,000 | 80,250 (0%) | 0% | 0 | Common Stock | |
| Carrie L. Bourdow | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2018 | 250,000 | 250,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2018 | 250,000 | 254,500 (0%) | 0% | 0 | Common Stock | |
| Mark A. Demitrack | Sr VP & Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2018 | 125,000 | 125,000 | - | - | Stock Option (Right to Buy) | |
| Mark A. Demitrack | Sr VP & Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2018 | 125,000 | 125,000 (0%) | 0% | 0 | Common Stock | |
| Robert T. Yoder | Sr. VP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2018 | 100,000 | 100,000 (0%) | 0% | 0 | Common Stock | |
| Robert T. Yoder | Sr. VP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2018 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Carrie L. Bourdow | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Sep 2018 | 335,000 | 335,000 | - | - | Employee Stock Option (Right to Buy) | |
| Scott Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Sep 2018 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| John P. Hamill | VP Fin,Princ Fin&Acct Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Aug 2018 | 52,500 | 52,500 | - | - | Stock Option (Right to Buy) | |
| Mark A. Demitrack | Sr VP & Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2018 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Leon O. Moulder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Julie H. McHugh | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Adam Koppel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Sale of securities on an exchange or to another person at price $ 1.76 per share. | 22 Mar 2018 | 5,000 | 0 (0%) | 0% | 1.8 | 8,800 | Common Stock |
| John M. Limongelli | Sr. VP,General Counsel & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 44,000 | 44,000 | - | - | Employee Stock Option (Right to Buy) | |
| John M. Limongelli | Sr. VP,General Counsel & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 65,000 | 65,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 252,500 | 252,500 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 150,000 | 150,000 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 44,000 | 44,000 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 65,000 | 65,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jonathan Violin | SVP-Scientific Affairs & IR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 75,000 | 75,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jonathan Violin | SVP-Scientific Affairs & IR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 65,000 | 65,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | EVP & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 124,000 | 124,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | EVP & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 112,500 | 112,500 | - | - | Employee Stock Option (Right to Buy) | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 44,000 | 44,000 | - | - | Employee Stock Option (Right to Buy) | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 65,000 | 65,000 | - | - | Employee Stock Option (Right to Buy) | |
| David Geoghegan | Sr. VP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 75,000 | 75,000 | - | - | Employee Stock Option (Right to Buy) | |
| David Geoghegan | Sr. VP, Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 65,000 | 65,000 | - | - | Employee Stock Option (Right to Buy) | |
| John M. Limongelli | Sr. VP,General Counsel & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 66,000 | 66,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 225,000 | 225,000 | - | - | Employee Stock Option (Right to Buy) | |
| Michael W. Lark | Sr. VP, Research & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 66,000 | 66,000 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 66,000 | 66,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 66,000 | 66,000 | - | - | Employee Stock Option (Right to Buy) | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2017 | 66,000 | 66,000 | - | - | Employee Stock Option (Right to Buy) | |
| Leon O. Moulder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Julie H. McHugh | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Adam Koppel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| John M. Limongelli | Sr. VP,General Counsel & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2017 | 91,000 | 91,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2017 | 303,000 | 303,000 | - | - | Employee Stock Option (Right to Buy) | |
| Michael W. Lark | Sr. VP, Research & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2017 | 91,000 | 91,000 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2017 | 113,750 | 113,750 | - | - | Employee Stock Option (Right to Buy) | |
| David Soergel | Sr. VP,Clinical Dev. & CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2017 | 91,000 | 91,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2017 | 91,000 | 91,000 | - | - | Employee Stock Option (Right to Buy) | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2017 | 91,000 | 91,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.68 per share. | 23 Feb 2017 | 110,403 | 126,903 (0%) | 0% | 0.7 | 75,295 | Common Stock |
| Maxine Gowen | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2017 | 106,329 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2017 | 4,074 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Michael W. Lark | Sr. VP, Research & CSO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.68 per share. | 10 Feb 2017 | 12,815 | 98,460 (0%) | 0% | 0.7 | 8,740 | Common Stock |
| Michael W. Lark | Sr. VP, Research & CSO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2017 | 12,815 | 48,362 | - | - | Employee Stock Option (Right to Buy) | |
| Michael W. Lark | Sr. VP, Research & CSO | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 10 Feb 2017 | 23,699 | 74,761 (0%) | 0% | 8 | 189,592 | Common Stock |
| John M. Limongelli | Sr. VP,General Counsel & CAO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2017 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 403 | 195,512 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2017 | 175,000 | 175,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 50,000 | 64,403 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 50,000 | 195,109 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 60,000 | 4,403 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 60,000 | 216,500 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 403 | 4,000 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 150,000 | 4,000 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 150,000 | 150,000 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 6,500 | 120,403 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 6,500 | 156,500 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 6,000 | 114,403 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Jan 2017 | 6,000 | 145,109 (0%) | 0% | 0 | Common Stock | |
| Michael W. Lark | Sr. VP, Research & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2017 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2017 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| David Soergel | Sr. VP,Clinical Dev. & CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2017 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2017 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2017 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | SVP, Chief Commercial Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Nov 2016 | 4,000 | 4,500 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Nov 2016 | 12,500 | 16,500 | - | - | Common Stock | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Nov 2016 | 5,000 | 5,000 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 20 Oct 2016 | 4,084 | 4,000 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 20 Oct 2016 | 4,084 | 139,109 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 20 Oct 2016 | 10,000 | 154,000 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 20 Oct 2016 | 10,000 | 8,084 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Sep 2016 | 130,000 | 134,000 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Sep 2016 | 10,000 | 144,000 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Sep 2016 | 10,000 | 18,084 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Sep 2016 | 135,025 | 135,025 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Sep 2016 | 130,000 | 163,109 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Sep 2016 | 135,025 | 28,084 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 May 2016 | 4,000 | 4,000 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 May 2016 | 4,000 | 279,025 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 May 2016 | 14,084 | 293,109 | - | - | Common Stock | |
| Leon O. Moulder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2016 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2016 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2016 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Julie H. McHugh | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2016 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Adam Koppel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2016 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2016 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2016 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| John M. Limongelli | Sr. VP,General Counsel & Secy | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2016 | 118,750 | 118,750 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2016 | 350,000 | 350,000 | - | - | Employee Stock Option (Right to Buy) | |
| Michael W. Lark | Sr. VP, Research & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2016 | 118,750 | 118,750 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2016 | 95,000 | 95,000 | - | - | Employee Stock Option (Right to Buy) | |
| David Soergel | Sr. VP,Clinical Dev. & CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2016 | 105,000 | 105,000 | - | - | Employee Stock Option (Right to Buy) | |
| Carrie L. Bourdow | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2016 | 95,000 | 95,000 | - | - | Employee Stock Option (Right to Buy) | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2016 | 95,000 | 95,000 | - | - | Employee Stock Option (Right to Buy) | |
| David Soergel | Sr. VP,Clinical Dev. & CMO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Dec 2015 | 27,217 | 1,750 | - | - | Common Stock | |
| Jake R. Nunn | None | Other type of transaction at price $ 0.00 per share. | 09 Dec 2015 | 4,271 | 4,271 | - | - | Common Stock | |
| Yacoub Habib | SVP, Bus Dev & Corp Planning | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jul 2015 | 125,000 | 125,000 | - | - | Employee Stock Option (Right to Buy) | |
| Francois Nader | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Leon O. Moulder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Director Stock Option (Right to Buy) | |
| Julie H. McHugh | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Adam Koppel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Anne M. Phillips | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2015 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Carrie L. Bourdow | SVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2015 | 125,000 | 125,000 | - | - | Employee Stock Option (Right to Buy) | |
| John M. Limongelli | Sr. VP,General Counsel & Secy | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2015 | 70,000 | 70,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2015 | 300,000 | 300,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Mar 2015 | 51,000 | 275,025 | - | - | Common Stock | |
| Michael W. Lark | Sr. VP, Research & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2015 | 87,500 | 87,500 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2015 | 70,000 | 70,000 | - | - | Employee Stock Option (Right to Buy) | |
| David Soergel | Sr. VP,Clinical Dev. & CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2015 | 87,500 | 87,500 | - | - | Employee Stock Option (Right to Buy) | |
| Anne M. Phillips | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2014 | 17,741 | 17,741 | - | - | Stock Option (Right to Buy) | |
| John M. Limongelli | Sr. VP,General Counsel & Secy | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Dec 2014 | 3,000 | 12,000 | - | - | Common Stock | |
| John M. Limongelli | Sr. VP,General Counsel & Secy | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Dec 2014 | 9,000 | 9,000 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Dec 2014 | 8,000 | 326,025 | - | - | Common Stock | |
| Michael R. Dougherty | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Dec 2014 | 7,000 | 7,000 | - | - | Common Stock | |
| Michael W. Lark | Sr. VP, Research & CSO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Dec 2014 | 5,000 | 85,645 | - | - | Common Stock | |
| Roberto Cuca | Sr. VP and CFO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Dec 2014 | 25,000 | 25,000 | - | - | Common Stock | |
| Barbara Yanni | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Dec 2014 | 1,250 | 1,250 | - | - | Common Stock | |
| Leon O. Moulder | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Dec 2014 | 30,200 | 30,200 | - | - | Common Stock | |
| Leon O. Moulder | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Dec 2014 | 19,800 | 50,000 | - | - | Common Stock | |
| David Soergel | Sr. VP, Clinical Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Dec 2014 | 500 | 27,717 | - | - | Common Stock | |
| David Soergel | Sr. VP, Clinical Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Dec 2014 | 1,250 | 28,967 | - | - | Common Stock | |
| Rosamond Deegan | Sr VP, Bus Dev & Operations | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 29 Sep 2014 | 44 | 31,105 | - | - | Common Stock | |
| Adam Koppel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Sep 2014 | 17,741 | 17,741 | - | - | Stock Option (Right to Buy) | |
| Julie H. McHugh | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2014 | 17,741 | 17,741 | - | - | Stock Option (Right to Buy) | |
| Barbara Yanni | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2014 | 17,741 | 17,741 | - | - | Stock Option (Right to Buy) | |
| Francois Nader | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Howard Solomon | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| John M. Limongelli | Sr. VP,General Counsel & Secy | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 100,000 | 100,000 | - | - | Employee Stock Option (Right to Buy) | |
| Leon O. Moulder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Terrance G. Mcguire | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Michael R. Dougherty | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Jake R. Nunn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 8,870 | 8,870 | - | - | Director Stock Option (Right to Buy) | |
| Farah Champsi | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 8,870 | 8,870 | - | - | Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Apr 2014 | 124,477 | 318,025 | - | - | Common Stock | |
| Maxine Gowen | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Apr 2014 | 124,477 | 106,329 | - | - | Employee Stock Option (Right to Buy) | |
| Robert Prachar | Sr. VP, Corp. Strategy | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2014 | 100,000 | 100,000 | - | - | Employee Stock Option (Right to Buy) | |
| Maxine Gowen | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Feb 2014 | 175,000 | 175,000 | - | - | Employee Stock Option (Right to Buy) | |
| Michael W. Lark | Sr. VP, Research & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Feb 2014 | 50,000 | 50,000 | - | - | Employee Stock Option (Right to Buy) | |
| Roberto Cuca | Sr. VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Feb 2014 | 50,000 | 50,000 | - | - | Employee Stock Option (Right to Buy) | |
| David Soergel | Sr. VP, Clinical Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Feb 2014 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Rosamond Deegan | Sr VP, Bus Dev & Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Feb 2014 | 60,000 | 60,000 | - | - | Employee Stock Option (Right to Buy) |