951.4K XNAS Volume
XNAS 19 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Magda Michna | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 43,989 | 43,989 | - | - | Restricted Stock Units | |
| Magda Michna | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 8,798 | 8,798 | - | - | Restricted Stock Units | |
| Nathaniel Sisitsky | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 8,798 | 8,798 | - | - | Restricted Stock Units | |
| Nathaniel Sisitsky | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 43,989 | 43,989 | - | - | Restricted Stock Units | |
| Warren Foust | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 29,326 | 29,326 | - | - | Restricted Stock Units | |
| Warren Foust | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 58,651 | 58,651 | - | - | Restricted Stock Units | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 8,153 | 56,242 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 8,153 | 16,307 | - | - | Restricted Stock Units | |
| Magda Michna | Chief Clinical, Regulatory | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 6,177 | 18,554 (0%) | 0% | 0 | Common Stock | |
| Magda Michna | Chief Clinical, Regulatory | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 6,177 | 12,356 | - | - | Restricted Stock Units | |
| Magda Michna | Chief Clinical, Regulatory | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.00 per share. | 12 Mar 2025 | 2,435 | 16,119 (0%) | 0% | 18 | 43,830 | Common Stock |
| Nathaniel Sisitsky | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 5,827 | 11,654 | - | - | Restricted Stock Units | |
| Nathaniel Sisitsky | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 5,827 | 27,762 (0%) | 0% | 0 | Common Stock | |
| Nathaniel Sisitsky | General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.00 per share. | 12 Mar 2025 | 2,334 | 25,428 (0%) | 0% | 18 | 42,012 | Common Stock |
| Warren Foust | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 8,175 | 16,350 | - | - | Restricted Stock Units | |
| Warren Foust | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2025 | 8,175 | 26,088 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 4,061 | 4,062 | - | - | Restricted Stock Units | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 2,614 | 40,953 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 3,075 | 44,028 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 4,061 | 48,089 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 2,614 | 0 | - | - | Performance Stock Units | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 3,075 | 0 | - | - | Restricted Stock Units | |
| Stephen C. Farrell | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.54 per share. | 05 Mar 2025 | 10,000 | 25,156 (0%) | 0% | 5.5 | 55,400 | Common Stock |
| Stephen C. Farrell | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.35 per share. | 05 Mar 2025 | 10,000 | 35,156 (0%) | 0% | 8.4 | 83,500 | Common Stock |
| Stephen C. Farrell | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 10,000 | 0 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 10,000 | 0 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 200,000 | 200,000 | - | - | Restricted Stock Units | |
| Thomas G. Frinzi | Director, President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.54 per share. | 03 Jan 2025 | 10,775 | 70,519 (0%) | 0% | 24.5 | 264,419 | Common Stock |
| Arthur C. Butcher | Director | Purchase of securities on an exchange or from another person at price $ 37.99 per share. | 12 Aug 2024 | 1,315 | 4,208 (0%) | 0% | 38.0 | 49,957 | Common Stock |
| Aimee S. Weisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 4,488 | 15,352 (0%) | 0% | 0 | Common Stock | |
| Stephen C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 4,010 | 4,010 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,244 | 15,156 (0%) | 0% | 0 | Common Stock | |
| Arthur C. Butcher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 4,010 | 4,010 | - | - | Common Stock Options | |
| Arthur C. Butcher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,244 | 2,893 (0%) | 0% | 0 | Common Stock | |
| Elizabeth Yeu-Lin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 4,010 | 4,010 | - | - | Common Stock Options | |
| Elizabeth Yeu-Lin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,244 | 5,099 (0%) | 0% | 0 | Common Stock | |
| Wei Jiang | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 4,010 | 4,010 | - | - | Common Stock Options | |
| Wei Jiang | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,244 | 3,543 (0%) | 0% | 0 | Common Stock | |
| Lilian Zhou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 4,010 | 4,010 | - | - | Common Stock Options | |
| Lilian Zhou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,244 | 4,571 (0%) | 0% | 0 | Common Stock | |
| Magda Michna | Chief Clinical, Regulatory | Payment of exercise price or tax liability using portion of securities received from the company at price $ 41.02 per share. | 08 May 2024 | 1,670 | 12,377 (0%) | 0% | 41.0 | 68,503 | Common Stock |
| Warren Foust | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 41.02 per share. | 08 May 2024 | 2,418 | 17,913 (0%) | 0% | 41.0 | 99,186 | Common Stock |
| Aimee S. Weisner | Director | Purchase of securities on an exchange or from another person at price $ 38.11 per share. | 14 Mar 2024 | 1,750 | 10,864 (0%) | 0% | 38.1 | 66,693 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 21,908 | 21,908 | - | - | Common Stock Options | |
| Patrick F. Williams | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 24,460 | 24,460 | - | - | Restricted Stock Units | |
| Thomas G. Frinzi | Director, President & CEO | 12 Mar 2024 | 66,627 | 66,627 | - | - | Common Stock Options | ||
| Thomas G. Frinzi | Director, President & CEO | 12 Mar 2024 | 74,389 | 74,389 | - | - | Restricted Stock Units | ||
| Arthur C. Butcher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 649 | 649 (0%) | 0% | 0 | Common Stock | |
| Arthur C. Butcher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 1,163 | 1,163 | - | - | Common Stock Options | |
| Magda Michna | Chief Clinical, Regulatory | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 16,599 | 16,599 | - | - | Common Stock Options | |
| Magda Michna | Chief Clinical, Regulatory | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 18,533 | 18,533 | - | - | Restricted Stock Units | |
| Wei Jiang | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 1,299 | 1,299 (0%) | 0% | 0 | Common Stock | |
| Wei Jiang | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 1,061 | 1,061 | - | - | Restricted Stock Units | |
| Warren Foust | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 21,966 | 21,996 | - | - | Common Stock Options | |
| Warren Foust | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 24,525 | 24,525 | - | - | Restricted Stock Units | |
| Nathaniel Sisitsky | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 17,481 | 17,481 | - | - | Restricted Stock Units | |
| Nathaniel Sisitsky | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 15,657 | 15,657 | - | - | Common Stock Options | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2024 | 2,614 | 45,475 (0%) | 0% | 0 | Common Stock | |
| Thomas Frinzi G. | Director, President & CEO | 03 Jan 2024 | 10,739 | 81,294 (0%) | 0% | 29.2 | 313,579 | Common Shares | |
| Farrell C. Stephen | Director | Grant, award, or other acquisition of securities at price $ 31.21 per share. | 29 Dec 2023 | 921 | 12,912 (0%) | 0% | 31.2 | 28,744 | Common Stock |
| S. Weisner Aimee | Director | Grant, award, or other acquisition of securities at price $ 31.21 per share. | 29 Dec 2023 | 3,200 | 9,114 (0%) | 0% | 31.2 | 99,872 | Common Stock |
| Lillian Zhou | Director | Purchase of securities on an exchange or from another person at price $ 30.74 per share. | 06 Dec 2023 | 850 | 2,327 (0%) | 0% | 30.7 | 26,129 | Common Stock |
| Lillian Zhou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Dec 2023 | 2,686 | 2,686 | - | - | Common Stock | |
| Lillian Zhou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Dec 2023 | 1,477 | 1,477 (0%) | 0% | 0 | Common Stock | |
| Kliman H. Gilbert | Director | Grant, award, or other acquisition of securities at price $ 32.99 per share. | 01 Dec 2023 | 366 | 10,457 (0%) | 0% | 33.0 | 12,074 | Common Stock |
| Aimee S. Weisner | Director | Purchase of securities on an exchange or from another person at price $ 48.72 per share. | 07 Aug 2023 | 2,000 | 5,417 (0%) | 0% | 48.7 | 97,440 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 54.79 per share. | 06 Jun 2023 | 1,987 | 45,400 (0%) | 0% | 54.8 | 108,868 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2023 | 5,121 | 47,387 (0%) | 0% | 0 | Common Stock | |
| Magda Michna | Chief Clinical, Regulatory | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2023 | 25,955 | 25,955 | - | - | Common Stock Options | |
| Magda Michna | Chief Clinical, Regulatory | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2023 | 14,047 | 14,047 (0%) | 0% | 0 | Common Stock | |
| Warren Foust | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2023 | 37,567 | 37,567 | - | - | Common Stock Options | |
| Warren Foust | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2023 | 20,331 | 20,331 (0%) | 0% | 0 | Common Stock | |
| Samuel Gesten | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.07 per share. | 20 Mar 2023 | 892 | 43,665 (0%) | 0% | 62.1 | 55,366 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.07 per share. | 20 Mar 2023 | 797 | 42,660 (0%) | 0% | 62.1 | 49,470 | Common Stock |
| Keith Holliday | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.07 per share. | 20 Mar 2023 | 907 | 28,157 (0%) | 0% | 62.1 | 56,297 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.07 per share. | 20 Mar 2023 | 911 | 41,502 (0%) | 0% | 62.1 | 56,546 | Common Stock |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 61.97 per share. | 17 Mar 2023 | 823 | 27,633 (0%) | 0% | 62.0 | 51,001 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 17,430 | 17,430 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.63 per share. | 10 Mar 2023 | 280 | 33,688 (0%) | 0% | 56.6 | 15,856 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 9,531 | 43,219 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 12,184 | 45,676 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 22,281 | 22,281 | - | - | Common Stock Options | |
| Patrick F. Williams | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.63 per share. | 10 Mar 2023 | 289 | 33,492 (0%) | 0% | 56.6 | 16,366 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 8,388 | 42,374 (0%) | 0% | 0 | Common Stock | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 15,339 | 15,339 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.63 per share. | 10 Mar 2023 | 250 | 33,986 (0%) | 0% | 56.6 | 14,158 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 18,638 | 18,638 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.63 per share. | 10 Mar 2023 | 284 | 18,264 (0%) | 0% | 56.6 | 16,083 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 10,192 | 28,456 (0%) | 0% | 0 | Common Stock | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 19,301 | 19,301 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 10,555 | 40,810 (0%) | 0% | 0 | Common Stock | |
| Scott D. Barnes | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.63 per share. | 10 Mar 2023 | 285 | 30,255 (0%) | 0% | 56.6 | 16,140 | Common Stock |
| Robert Studholme | Senior VP, Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 16,200 | 16,200 | - | - | Common Stock Options | |
| Robert Studholme | Senior VP, Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2023 | 8,859 | 31,980 (0%) | 0% | 0 | Common Stock | |
| Samuel Gesten | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 58.13 per share. | 07 Mar 2023 | 831 | 33,968 (0%) | 0% | 58.1 | 48,306 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.13 per share. | 07 Mar 2023 | 1,338 | 35,306 (0%) | 0% | 58.1 | 77,778 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 58.13 per share. | 07 Mar 2023 | 1,063 | 33,781 (0%) | 0% | 58.1 | 61,792 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.13 per share. | 07 Mar 2023 | 1,711 | 35,492 (0%) | 0% | 58.1 | 99,460 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.13 per share. | 07 Mar 2023 | 1,083 | 35,319 (0%) | 0% | 58.1 | 62,955 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 58.13 per share. | 07 Mar 2023 | 672 | 34,236 (0%) | 0% | 58.1 | 39,063 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.13 per share. | 07 Mar 2023 | 1,431 | 19,979 (0%) | 0% | 58.1 | 83,184 | Common Stock |
| Keith Holliday | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 58.13 per share. | 07 Mar 2023 | 889 | 18,548 (0%) | 0% | 58.1 | 51,678 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.13 per share. | 07 Mar 2023 | 1,603 | 32,143 (0%) | 0% | 58.1 | 93,182 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 58.13 per share. | 07 Mar 2023 | 777 | 30,540 (0%) | 0% | 58.1 | 45,167 | Common Stock |
| Robert Studholme | Senior VP, Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.13 per share. | 07 Mar 2023 | 1,709 | 23,121 (0%) | 0% | 58.1 | 99,344 | Common Shares |
| Thomas G. Frinzi | Director, President & CEO | 03 Jan 2023 | 160,638 | 160,638 | - | - | Common Stock Options | ||
| Thomas G. Frinzi | Director, President & CEO | 03 Jan 2023 | 87,805 | 92,534 (0%) | 0% | 0 | Common Shares | ||
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Dec 2022 | 19,139 | 19,139 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Sep 2022 | 13,075 | 0 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 75.00 per share. | 27 Sep 2022 | 13,075 | 34,908 (0%) | 0% | 75 | 980,625 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 27 Sep 2022 | 13,075 | 47,983 (0%) | 0% | 7.5 | 98,324 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 75.00 per share. | 27 Sep 2022 | 15,683 | 34,908 (0%) | 0% | 75 | 1,176,225 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 75.00 per share. | 27 Sep 2022 | 6,667 | 50,591 (0%) | 0% | 75 | 500,025 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 15 Aug 2022 | 9,388 | 36,019 (0%) | 0% | 36.0 | 337,780 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 15 Aug 2022 | 695 | 25,132 (0%) | 0% | 16.1 | 11,224 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 15 Aug 2022 | 1,499 | 26,631 (0%) | 0% | 29.8 | 44,670 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 9,388 | 0 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 1,499 | 0 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 695 | 0 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 106.22 per share. | 15 Aug 2022 | 5,000 | 19,437 (0%) | 0% | 106.2 | 531,100 | Common Stock |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 106.32 per share. | 15 Aug 2022 | 11,582 | 24,347 (0%) | 0% | 106.3 | 1,231,398 | Common Stock |
| Aimee S. Weisner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 5,765 | 5,765 | - | - | Common Stock Options | |
| Gilbert H. Kliman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 2,899 | 6,239 (0%) | 0% | 0 | Common Stock | |
| Gilbert H. Kliman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 355 | 3,340 (0%) | 0% | 0 | Common Stock | |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 355 | 6,567 (0%) | 0% | 0 | Common Stock | |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 5,765 | 5,765 | - | - | Common Stock Options | |
| K. Peony Yu | Director | 16 Jun 2022 | 5,765 | 5,765 | - | - | Common Stock Options | ||
| K. Peony Yu | Director | 16 Jun 2022 | 355 | 1,077 (0%) | 0% | 0 | Common Stock | ||
| Thomas G. Frinzi | Director | 16 Jun 2022 | 355 | 3,279 (0%) | 0% | 0 | Common Stock | ||
| Thomas G. Frinzi | Director | 16 Jun 2022 | 1,450 | 4,729 (0%) | 0% | 0 | Common Stock | ||
| Thomas G. Frinzi | Director | 16 Jun 2022 | 2,881 | 2,881 | - | - | Common Stock Options | ||
| Elizabeth Yeu-Lin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 5,765 | 5,765 | - | - | Common Stock Options | |
| Elizabeth Yeu-Lin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 355 | 355 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Jun 2022 | 5,121 | 34,844 (0%) | 0% | 0 | Common Stock | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2022 | 12,886 | 40,114 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2022 | 34,928 | 65,072 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2022 | 14,765 | 80,235 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2022 | 6,191 | 68,809 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 06 Jun 2022 | 14,765 | 146,224 (0%) | 0% | 9.3 | 137,315 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 06 Jun 2022 | 12,886 | 96,531 (0%) | 0% | 7.8 | 99,995 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 06 Jun 2022 | 6,191 | 152,415 (0%) | 0% | 16.2 | 99,985 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 06 Jun 2022 | 34,928 | 131,459 (0%) | 0% | 7.5 | 262,659 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 18 May 2022 | 35,000 | 118,645 (0%) | 0% | 9.3 | 325,500 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 May 2022 | 35,000 | 95,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 May 2022 | 35,000 | 130,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 May 2022 | 35,000 | 165,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 58.48 per share. | 18 May 2022 | 35,000 | 83,645 (0%) | 0% | 58.5 | 2,046,800 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 18 May 2022 | 35,000 | 118,645 (0%) | 0% | 9.3 | 325,500 | Common Stock |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 57.49 per share. | 18 May 2022 | 35,000 | 83,645 (0%) | 0% | 57.5 | 2,012,150 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 18 May 2022 | 35,000 | 118,645 (0%) | 0% | 9.3 | 325,500 | Common Stock |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 56.46 per share. | 18 May 2022 | 35,000 | 83,645 (0%) | 0% | 56.5 | 1,976,100 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 74.62 per share. | 21 Mar 2022 | 922 | 57,258 (0%) | 0% | 74.6 | 68,800 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 64.18 per share. | 14 Mar 2022 | 289 | 58,180 (0%) | 0% | 64.2 | 18,548 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 42,160 | 42,160 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 20,269 | 83,645 (0%) | 0% | 0 | Common Stock | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 12,293 | 12,293 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 5,910 | 83,110 (0%) | 0% | 0 | Common Stock | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 7,216 | 34,799 (0%) | 0% | 0 | Common Stock | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 15,010 | 15,010 | - | - | Common Stock Options | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 9,225 | 34,844 (0%) | 0% | 0 | Common Stock | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 19,188 | 19,188 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 12,146 | 12,146 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 5,839 | 58,469 (0%) | 0% | 0 | Common Stock | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 16,051 | 16,051 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 7,716 | 24,437 (0%) | 0% | 0 | Common Stock | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 16,621 | 16,621 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2022 | 7,991 | 31,317 (0%) | 0% | 0 | Common Stock | |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 89.57 per share. | 14 Dec 2021 | 6,000 | 16,721 (0%) | 0% | 89.6 | 537,420 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 16 Nov 2021 | 35,000 | 98,376 (0%) | 0% | 7.8 | 271,600 | Common Stock |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 114.20 per share. | 16 Nov 2021 | 35,000 | 63,376 (0%) | 0% | 114.2 | 3,997,000 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 16 Nov 2021 | 35,000 | 98,376 (0%) | 0% | 7.8 | 271,600 | Common Stock |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 113.83 per share. | 16 Nov 2021 | 35,000 | 63,376 (0%) | 0% | 113.8 | 3,984,050 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 16 Nov 2021 | 35,000 | 98,376 (0%) | 0% | 7.8 | 271,600 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2021 | 35,000 | 88,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2021 | 35,000 | 53,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 113.83 per share. | 16 Nov 2021 | 35,000 | 63,376 (0%) | 0% | 113.8 | 3,984,050 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2021 | 35,000 | 123,000 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 114.53 per share. | 04 Oct 2021 | 15,000 | 27,583 (0%) | 0% | 114.5 | 1,717,950 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 139.38 per share. | 16 Sep 2021 | 5,121 | 25,619 (0%) | 0% | 139.4 | 713,765 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 07 Sep 2021 | 14,031 | 91,231 (0%) | 0% | 36.0 | 504,835 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Sep 2021 | 15,100 | 16,879 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Sep 2021 | 14,031 | 4,109 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 157.40 per share. | 07 Sep 2021 | 29,131 | 77,200 (0%) | 0% | 157.4 | 4,585,219 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.53 per share. | 07 Sep 2021 | 15,100 | 106,331 (0%) | 0% | 27.5 | 415,703 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 157.40 per share. | 07 Sep 2021 | 11,522 | 77,200 (0%) | 0% | 157.4 | 1,813,563 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 157.61 per share. | 01 Sep 2021 | 17,573 | 99,760 (0%) | 0% | 157.6 | 2,769,681 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 2,988 | 18,140 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 13,484 | 0 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 871 | 0 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 17,573 | 871 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 157.50 per share. | 01 Sep 2021 | 17,343 | 88,722 (0%) | 0% | 157.5 | 2,731,523 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 01 Sep 2021 | 2,988 | 106,065 (0%) | 0% | 36.0 | 107,508 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 01 Sep 2021 | 13,484 | 103,077 (0%) | 0% | 29.8 | 401,823 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 01 Sep 2021 | 871 | 89,593 (0%) | 0% | 16.2 | 14,067 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 157.50 per share. | 01 Sep 2021 | 11,038 | 88,722 (0%) | 0% | 157.5 | 1,738,485 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 01 Sep 2021 | 17,573 | 117,333 (0%) | 0% | 16.2 | 283,804 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 157.61 per share. | 01 Sep 2021 | 8,621 | 99,760 (0%) | 0% | 157.6 | 1,358,756 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2021 | 3,664 | 6,836 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2021 | 5,000 | 13,075 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 146.91 per share. | 18 Aug 2021 | 15,000 | 52,630 (0%) | 0% | 146.9 | 2,203,650 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 18 Aug 2021 | 6,336 | 67,630 (0%) | 0% | 29.8 | 188,813 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 18 Aug 2021 | 3,664 | 61,294 (0%) | 0% | 16.2 | 59,174 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 18 Aug 2021 | 5,000 | 57,630 (0%) | 0% | 7.5 | 37,600 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2021 | 6,336 | 7,148 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 12 Aug 2021 | 6,667 | 49,250 (0%) | 0% | 16.1 | 107,672 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 12 Aug 2021 | 4,495 | 53,746 (0%) | 0% | 29.8 | 133,951 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 12 Aug 2021 | 11,364 | 65,110 (0%) | 0% | 36.0 | 408,877 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2021 | 7,156 | 8,946 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2021 | 11,364 | 5,682 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2021 | 4,495 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2021 | 6,667 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 134.71 per share. | 12 Aug 2021 | 29,682 | 42,583 (0%) | 0% | 134.7 | 3,998,462 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.53 per share. | 12 Aug 2021 | 7,156 | 72,266 (0%) | 0% | 27.5 | 197,005 | Common Stock |
| Louis E. Silverman | Director | Sale of securities on an exchange or to another person at price $ 145.56 per share. | 10 Aug 2021 | 10,000 | 2,924 (0%) | 0% | 145.6 | 1,455,600 | Common Stock |
| Louis E. Silverman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2021 | 9,921 | 0 | - | - | Common Stock Options | |
| Louis E. Silverman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2021 | 10,000 | 0 | - | - | Common Stock Options | |
| Louis E. Silverman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2021 | 10,000 | 0 | - | - | Common Stock Options | |
| Louis E. Silverman | Director | Sale of securities on an exchange or to another person at price $ 145.54 per share. | 10 Aug 2021 | 9,921 | 2,924 (0%) | 0% | 145.5 | 1,443,902 | Common Stock |
| Louis E. Silverman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.60 per share. | 10 Aug 2021 | 9,921 | 12,845 (0%) | 0% | 9.6 | 95,242 | Common Stock |
| Louis E. Silverman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.35 per share. | 10 Aug 2021 | 10,000 | 12,924 (0%) | 0% | 8.4 | 83,500 | Common Stock |
| Louis E. Silverman | Director | Sale of securities on an exchange or to another person at price $ 145.57 per share. | 10 Aug 2021 | 10,000 | 2,924 (0%) | 0% | 145.6 | 1,455,700 | Common Stock |
| Louis E. Silverman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.31 per share. | 10 Aug 2021 | 10,000 | 12,924 (0%) | 0% | 9.3 | 93,100 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 140.58 per share. | 10 Aug 2021 | 2,500 | 30,740 (0%) | 0% | 140.6 | 351,450 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2021 | 5,121 | 33,240 (0%) | 0% | 0 | Common Stock | |
| Gilbert H. Kliman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jun 2021 | 850 | 850 | - | - | Common Stock Options | |
| Gilbert H. Kliman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2021 | 404 | 2,985 (0%) | 0% | 0 | Common Stock | |
| Louis E. Silverman | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jun 2021 | 807 | 2,924 (0%) | 0% | 0 | Common Stock | |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jun 2021 | 850 | 850 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jun 2021 | 404 | 6,212 (0%) | 0% | 0 | Common Stock | |
| K. Peony Yu | Director | 24 Jun 2021 | 404 | 722 (0%) | 0% | 0 | Common Stock | ||
| K. Peony Yu | Director | 24 Jun 2021 | 850 | 850 | - | - | Common Stock Options | ||
| Thomas G. Frinzi | Director | 24 Jun 2021 | 807 | 2,924 (0%) | 0% | 0 | Common Stock | ||
| Elizabeth Yeu | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2021 | 1,703 | 1,703 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director | Sale or transfer of securities back to the company at price $ 135.00 per share. | 26 May 2021 | 5,000 | 5,808 (0%) | 0% | 135 | 675,000 | Common Stock |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 May 2021 | 5,000 | 10,000 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 May 2021 | 5,000 | 0 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director | Sale or transfer of securities back to the company at price $ 150.00 per share. | 26 May 2021 | 5,000 | 5,808 (0%) | 0% | 150 | 750,000 | Common Stock |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.54 per share. | 26 May 2021 | 5,000 | 10,808 (0%) | 0% | 5.5 | 27,700 | Common Stock |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.14 per share. | 26 May 2021 | 5,000 | 10,808 (0%) | 0% | 7.1 | 35,700 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 4,201 | 25,799 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 6,556 | 18,444 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 22,500 | 0 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.54 per share. | 21 May 2021 | 944 | 109,325 (0%) | 0% | 15.5 | 14,670 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.35 per share. | 21 May 2021 | 4,201 | 113,526 (0%) | 0% | 7.3 | 30,877 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 128.00 per share. | 21 May 2021 | 5,145 | 108,381 (0%) | 0% | 128 | 658,560 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.35 per share. | 21 May 2021 | 25,799 | 134,180 (0%) | 0% | 7.4 | 189,623 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 21 May 2021 | 40,000 | 174,180 (0%) | 0% | 7.5 | 300,800 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 40,000 | 0 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 21 May 2021 | 22,500 | 196,680 (0%) | 0% | 9.3 | 209,250 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 21 May 2021 | 6,556 | 203,236 (0%) | 0% | 16.1 | 105,879 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 130.42 per share. | 21 May 2021 | 94,855 | 108,381 (0%) | 0% | 130.4 | 12,370,989 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 944 | 0 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 25,799 | 0 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 21 May 2021 | 15,261 | 67,891 (0%) | 0% | 9.3 | 141,927 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 14,500 | 10,500 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 15,261 | 14,739 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 130.42 per share. | 21 May 2021 | 14,500 | 52,630 (0%) | 0% | 130.4 | 1,891,090 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 21 May 2021 | 14,500 | 67,130 (0%) | 0% | 16.2 | 234,175 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 126.83 per share. | 21 May 2021 | 15,261 | 52,630 (0%) | 0% | 126.8 | 1,935,553 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 7,566 | 11,891 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 21 May 2021 | 2,500 | 25,826 (0%) | 0% | 16.2 | 40,375 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 21 May 2021 | 2,229 | 28,055 (0%) | 0% | 36.0 | 80,199 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.53 per share. | 21 May 2021 | 7,566 | 35,621 (0%) | 0% | 27.5 | 208,292 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 126.05 per share. | 21 May 2021 | 12,295 | 23,326 (0%) | 0% | 126.1 | 1,549,785 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 2,500 | 5,200 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2021 | 2,229 | 9,157 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2021 | 5,000 | 15,000 | - | - | Common Stock Options | |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.54 per share. | 19 May 2021 | 5,000 | 10,808 (0%) | 0% | 5.5 | 27,700 | Common Stock |
| Stephen C. Farrell | Director | Sale or transfer of securities back to the company at price $ 120.00 per share. | 19 May 2021 | 5,000 | 5,808 (0%) | 0% | 120 | 600,000 | Common Stock |
| Stephen C. Farrell | Director | Sale or transfer of securities back to the company at price $ 113.87 per share. | 17 May 2021 | 5,328 | 5,808 (0%) | 0% | 113.9 | 606,699 | Common Stock |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.14 per share. | 17 May 2021 | 5,328 | 11,136 (0%) | 0% | 7.1 | 38,042 | Common Stock |
| Stephen C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 May 2021 | 5,328 | 5,000 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 11 May 2021 | 231 | 9,453 (0%) | 0% | 36.0 | 8,311 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 11 May 2021 | 1,050 | 15,428 (0%) | 0% | 36.0 | 37,779 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.53 per share. | 11 May 2021 | 10,025 | 25,453 (0%) | 0% | 27.5 | 275,988 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Sale of securities on an exchange or to another person at price $ 111.61 per share. | 11 May 2021 | 11,075 | 14,378 (0%) | 0% | 111.6 | 1,236,081 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Sale of securities on an exchange or to another person at price $ 110.74 per share. | 11 May 2021 | 5,531 | 8,847 (0%) | 0% | 110.7 | 612,503 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 11 May 2021 | 375 | 9,222 (0%) | 0% | 29.8 | 11,175 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 11 May 2021 | 348 | 9,801 (0%) | 0% | 16.1 | 5,620 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2021 | 1,050 | 7,272 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2021 | 10,025 | 17,737 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2021 | 375 | 375 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2021 | 231 | 7,041 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2021 | 348 | 0 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 53,500 | 158,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 53,500 | 211,500 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 110.70 per share. | 10 May 2021 | 53,500 | 63,376 (0%) | 0% | 110.7 | 5,922,450 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 10 May 2021 | 53,500 | 116,876 (0%) | 0% | 7.8 | 415,160 | Common Stock |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 119.88 per share. | 10 May 2021 | 53,500 | 63,376 (0%) | 0% | 119.9 | 6,413,580 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 10 May 2021 | 53,500 | 116,876 (0%) | 0% | 7.8 | 415,160 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.35 per share. | 10 May 2021 | 2,158 | 54,788 (0%) | 0% | 7.3 | 15,861 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 9,425 | 18,075 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 2,158 | 0 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 125.72 per share. | 10 May 2021 | 11,583 | 52,630 (0%) | 0% | 125.7 | 1,456,215 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 10 May 2021 | 9,425 | 64,213 (0%) | 0% | 7.5 | 70,876 | Common Stock |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 125.83 per share. | 10 May 2021 | 8,874 | 22,721 (0%) | 0% | 125.8 | 1,116,615 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.53 per share. | 10 May 2021 | 5,523 | 27,061 (0%) | 0% | 27.5 | 152,048 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 10 May 2021 | 3,462 | 21,538 (0%) | 0% | 36.0 | 124,563 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 10 May 2021 | 2,534 | 18,076 (0%) | 0% | 29.8 | 75,513 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 10 May 2021 | 7,200 | 15,542 (0%) | 0% | 16.2 | 116,280 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Sale of securities on an exchange or to another person at price $ 125.22 per share. | 10 May 2021 | 1,349 | 8,342 (0%) | 0% | 125.2 | 168,922 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 5,523 | 9,774 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 3,462 | 8,564 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 2,534 | 750 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Sale of securities on an exchange or to another person at price $ 124.13 per share. | 10 May 2021 | 10,760 | 16,301 (0%) | 0% | 124.1 | 1,335,639 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2021 | 7,200 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 96.37 per share. | 22 Mar 2021 | 1,032 | 42,583 (0%) | 0% | 96.4 | 99,454 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 96.37 per share. | 22 Mar 2021 | 922 | 52,630 (0%) | 0% | 96.4 | 88,853 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Sale of securities on an exchange or to another person at price $ 96.37 per share. | 22 Mar 2021 | 1,103 | 9,691 (0%) | 0% | 96.4 | 106,296 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Mar 2021 | 2,664 | 19,671 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 95.00 per share. | 16 Mar 2021 | 2,664 | 20,390 (0%) | 0% | 95 | 253,080 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.25 per share. | 16 Mar 2021 | 2,664 | 23,054 (0%) | 0% | 15.3 | 40,626 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 40,932 | 40,932 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 19,363 | 63,376 (0%) | 0% | 0 | Common Stock | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 11,154 | 11,154 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 2,430 | 43,615 (0%) | 0% | 0 | Common Stock | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 5,137 | 5,137 | - | - | Common Stock Options | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 5,312 | 5,312 | - | - | Common Stock Options | |
| Patrick F. Williams | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 2,513 | 33,240 (0%) | 0% | 0 | Common Stock | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 4,585 | 4,585 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 2,169 | 53,552 (0%) | 0% | 0 | Common Stock | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 2,471 | 31,595 (0%) | 0% | 0 | Common Stock | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 5,223 | 5,223 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 9,259 | 9,259 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 9,759 | 9,759 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 92.00 per share. | 11 Mar 2021 | 2,665 | 20,390 (0%) | 0% | 92 | 245,180 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.25 per share. | 11 Mar 2021 | 2,665 | 23,055 (0%) | 0% | 15.2 | 40,641 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 6,207 | 6,207 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 2,665 | 22,335 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 2,936 | 23,326 (0%) | 0% | 0 | Common Stock | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Mar 2021 | 4,800 | 7,700 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Mar 2021 | 2,345 | 11,386 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Mar 2021 | 188 | 1,124 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 89.25 per share. | 09 Mar 2021 | 4,033 | 20,390 (0%) | 0% | 89.2 | 359,945 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 88.48 per share. | 09 Mar 2021 | 3,300 | 24,423 (0%) | 0% | 88.5 | 291,984 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 09 Mar 2021 | 2,345 | 27,723 (0%) | 0% | 36.0 | 84,373 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 09 Mar 2021 | 188 | 25,378 (0%) | 0% | 29.8 | 5,602 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 09 Mar 2021 | 4,800 | 25,190 (0%) | 0% | 16.2 | 77,520 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 01 Mar 2021 | 45,000 | 89,013 (0%) | 0% | 7.8 | 349,200 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 01 Mar 2021 | 45,000 | 89,013 (0%) | 0% | 7.8 | 349,200 | Common Stock |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 103.53 per share. | 01 Mar 2021 | 45,000 | 44,013 (0%) | 0% | 103.5 | 4,658,850 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 01 Mar 2021 | 45,000 | 89,013 (0%) | 0% | 7.8 | 349,200 | Common Stock |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 104.76 per share. | 01 Mar 2021 | 45,000 | 44,013 (0%) | 0% | 104.8 | 4,714,200 | Common Stock |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 45,000 | 265,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 45,000 | 310,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 45,000 | 355,000 | - | - | Common Stock Options | |
| Caren L. Mason | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 98.32 per share. | 01 Mar 2021 | 45,000 | 44,013 (0%) | 0% | 98.3 | 4,424,400 | Common Stock |
| Louis E. Silverman | Director | Sale of securities on an exchange or to another person at price $ 104.78 per share. | 01 Mar 2021 | 23,996 | 2,117 (0%) | 0% | 104.8 | 2,514,301 | Common Stock |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 103.85 per share. | 01 Mar 2021 | 5,208 | 29,124 (0%) | 0% | 103.9 | 540,851 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 3,610 | 7,221 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 1,873 | 1,499 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 7,094 | 694 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 1,206 | 0 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 104.82 per share. | 01 Mar 2021 | 13,783 | 29,124 (0%) | 0% | 104.8 | 1,444,734 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 01 Mar 2021 | 3,610 | 42,907 (0%) | 0% | 36.0 | 129,888 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 01 Mar 2021 | 1,873 | 39,297 (0%) | 0% | 29.8 | 55,815 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 01 Mar 2021 | 7,094 | 37,424 (0%) | 0% | 16.1 | 114,568 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 01 Mar 2021 | 1,206 | 30,330 (0%) | 0% | 9.3 | 11,216 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.25 per share. | 01 Mar 2021 | 2,431 | 23,984 (0%) | 0% | 15.3 | 37,073 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 01 Mar 2021 | 14,491 | 45,914 (0%) | 0% | 36.0 | 521,386 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 01 Mar 2021 | 5,618 | 31,423 (0%) | 0% | 29.8 | 167,416 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 01 Mar 2021 | 229 | 25,805 (0%) | 0% | 36.0 | 8,239 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 01 Mar 2021 | 374 | 25,546 (0%) | 0% | 29.8 | 11,145 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 01 Mar 2021 | 1,218 | 25,202 (0%) | 0% | 16.2 | 19,671 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 2,069 | 348 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 185 | 2,417 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 14,491 | 8,322 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 5,618 | 750 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 229 | 22,813 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 374 | 6,368 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 1,218 | 2,602 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 2,431 | 0 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Sale of securities on an exchange or to another person at price $ 106.03 per share. | 01 Mar 2021 | 2,069 | 14,378 (0%) | 0% | 106.0 | 219,376 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 01 Mar 2021 | 2,069 | 16,447 (0%) | 0% | 16.1 | 33,414 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Sale of securities on an exchange or to another person at price $ 103.05 per share. | 01 Mar 2021 | 11,427 | 14,378 (0%) | 0% | 103.0 | 1,177,552 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Sale of securities on an exchange or to another person at price $ 103.21 per share. | 01 Mar 2021 | 20,294 | 25,805 (0%) | 0% | 103.2 | 2,094,544 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 01 Mar 2021 | 185 | 46,099 (0%) | 0% | 16.2 | 2,988 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Sale of securities on an exchange or to another person at price $ 105.43 per share. | 01 Mar 2021 | 16,000 | 10,794 (0%) | 0% | 105.4 | 1,686,880 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 16,000 | 12,026 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 01 Mar 2021 | 16,000 | 26,794 (0%) | 0% | 36.0 | 575,680 | Common Stock |
| K. Peony Yu | Director | 21 Jan 2021 | 684 | 684 | - | - | Common Stock Options | ||
| K. Peony Yu | Director | 21 Jan 2021 | 318 | 318 (0%) | 0% | 0 | Common Stock | ||
| John C. Moore | Director | Sale or transfer of securities back to the company at price $ 72.46 per share. | 02 Dec 2020 | 11,387 | 0 (0%) | 0% | 72.5 | 825,102 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.35 per share. | 23 Nov 2020 | 14,815 | 66,198 (0%) | 0% | 7.3 | 108,890 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.54 per share. | 23 Nov 2020 | 4,144 | 70,342 (0%) | 0% | 15.5 | 64,398 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 80.13 per share. | 23 Nov 2020 | 18,959 | 51,383 (0%) | 0% | 80.1 | 1,519,185 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2020 | 4,144 | 0 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2020 | 14,815 | 2,185 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2020 | 12,156 | 2,844 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2020 | 1,900 | 944 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.54 per share. | 19 Nov 2020 | 12,156 | 140,106 (0%) | 0% | 15.5 | 188,904 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 82.02 per share. | 19 Nov 2020 | 12,156 | 127,950 (0%) | 0% | 82.0 | 997,035 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 82.03 per share. | 19 Nov 2020 | 14,007 | 113,943 (0%) | 0% | 82.0 | 1,148,994 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 83.02 per share. | 19 Nov 2020 | 2,688 | 111,255 (0%) | 0% | 83.0 | 223,158 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.54 per share. | 19 Nov 2020 | 1,900 | 113,155 (0%) | 0% | 15.5 | 29,526 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 83.02 per share. | 19 Nov 2020 | 1,900 | 111,255 (0%) | 0% | 83.0 | 157,738 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 83.14 per share. | 19 Nov 2020 | 2,874 | 108,381 (0%) | 0% | 83.1 | 238,944 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 16 Nov 2020 | 17,163 | 42,983 (0%) | 0% | 36.0 | 617,525 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 80.25 per share. | 16 Nov 2020 | 22,593 | 20,390 (0%) | 0% | 80.2 | 1,813,088 | Common Stock |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2020 | 5,430 | 1,312 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2020 | 17,163 | 13,731 | - | - | Common Stock Options | |
| Scott D. Barnes | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 16 Nov 2020 | 5,430 | 25,820 (0%) | 0% | 29.8 | 161,814 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 09 Nov 2020 | 15,000 | 58,046 (0%) | 0% | 9.3 | 139,500 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Nov 2020 | 15,000 | 0 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Nov 2020 | 23,714 | 0 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 81.56 per share. | 09 Nov 2020 | 23,714 | 34,332 (0%) | 0% | 81.6 | 1,934,114 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 09 Nov 2020 | 23,714 | 43,046 (0%) | 0% | 7.5 | 178,329 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 09 Nov 2020 | 10,200 | 20,994 (0%) | 0% | 29.8 | 303,960 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Nov 2020 | 9,800 | 724 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Nov 2020 | 10,200 | 1,058 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Sale of securities on an exchange or to another person at price $ 81.34 per share. | 09 Nov 2020 | 20,000 | 10,794 (0%) | 0% | 81.3 | 1,626,800 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 09 Nov 2020 | 9,800 | 30,794 (0%) | 0% | 16.2 | 158,270 | Common Stock |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 53.26 per share. | 14 Sep 2020 | 26,574 | 28,447 (0%) | 0% | 53.3 | 1,415,331 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2020 | 12,997 | 12,998 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2020 | 10,112 | 3,372 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2020 | 13,217 | 7,789 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2020 | 3,994 | 21,006 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2020 | 21,294 | 16,206 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2020 | 1,286 | 23,714 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 53.33 per share. | 14 Sep 2020 | 36,326 | 19,332 (0%) | 0% | 53.3 | 1,937,266 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 35.98 per share. | 14 Sep 2020 | 12,997 | 55,658 (0%) | 0% | 36.0 | 467,632 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.80 per share. | 14 Sep 2020 | 10,112 | 42,661 (0%) | 0% | 29.8 | 301,338 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 14 Sep 2020 | 13,217 | 32,549 (0%) | 0% | 16.2 | 213,455 | Common Stock |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 53.49 per share. | 14 Sep 2020 | 9,115 | 19,332 (0%) | 0% | 53.5 | 487,561 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 14 Sep 2020 | 3,994 | 55,021 (0%) | 0% | 16.1 | 64,503 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 14 Sep 2020 | 21,294 | 51,027 (0%) | 0% | 9.3 | 198,034 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 14 Sep 2020 | 1,286 | 29,733 (0%) | 0% | 7.5 | 9,671 | Common Stock |
| John C. Moore | Director | Sale or transfer of securities back to the company at price $ 81.03 per share. | 09 Sep 2020 | 16,206 | 2,117 (0%) | 0% | 81.0 | 1,313,172 | Common Stock |
| John C. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 09 Sep 2020 | 1,206 | 18,323 (0%) | 0% | 16.2 | 19,477 | Common Stock |
| John C. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.31 per share. | 09 Sep 2020 | 5,000 | 7,117 (0%) | 0% | 10.3 | 51,550 | Common Stock |
| John C. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.73 per share. | 09 Sep 2020 | 10,000 | 17,117 (0%) | 0% | 15.7 | 157,300 | Common Stock |
| John C. Moore | Director | Sale of securities on an exchange or to another person at price $ 52.04 per share. | 09 Sep 2020 | 137,331 | 21,387 (0%) | 0% | 52.0 | 7,146,705 | Common Stock |
| John C. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Sep 2020 | 1,206 | 0 | - | - | Common Stock Options | |
| John C. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Sep 2020 | 10,000 | 0 | - | - | Common Stock Options | |
| John C. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Sep 2020 | 5,000 | 0 | - | - | Common Stock Options | |
| John C. Moore | Director | Sale or transfer of securities back to the company at price $ 80.88 per share. | 09 Sep 2020 | 14,254 | 11,387 (0%) | 0% | 80.9 | 1,152,864 | Common Stock |
| Patrick F. Williams | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2020 | 30,727 | 30,727 (0%) | 0% | 0 | Common Stock | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2020 | 8,000 | 6,476 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2020 | 11,574 | 0 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2020 | 5,822 | 0 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2020 | 16,206 | 0 | - | - | Common Stock Options | |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 10 Aug 2020 | 16,206 | 27,000 (0%) | 0% | 9.3 | 150,716 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 10 Aug 2020 | 8,000 | 52,396 (0%) | 0% | 16.2 | 129,200 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.64 per share. | 10 Aug 2020 | 11,574 | 44,396 (0%) | 0% | 8.6 | 99,999 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.52 per share. | 10 Aug 2020 | 5,822 | 32,822 (0%) | 0% | 7.5 | 43,781 | Common Stock |
| Jon K. Hayashida | VP, Global Clinical, Medical | Sale of securities on an exchange or to another person at price $ 51.22 per share. | 10 Aug 2020 | 41,602 | 10,794 (0%) | 0% | 51.2 | 2,130,854 | Common Stock |
| John C. Moore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jul 2020 | 2,117 | 2,117 (0%) | 0% | 0 | Common Stock | |
| Gilbert H. Kliman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jul 2020 | 2,117 | 2,581 (0%) | 0% | 0 | Common Stock | |
| Louis E. Silverman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jul 2020 | 2,117 | 15,850 (0%) | 0% | 0 | Common Stock | |
| Stephen C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jul 2020 | 2,117 | 5,808 (0%) | 0% | 0 | Common Stock | |
| Thomas G. Frinzi | Director | 30 Jul 2020 | 2,117 | 2,117 (0%) | 0% | 0 | Common Stock | ||
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 44.07 per share. | 15 Jun 2020 | 39,215 | 127,950 (0%) | 0% | 44.1 | 1,728,205 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.00 per share. | 15 Jun 2020 | 19,215 | 147,165 (0%) | 0% | 11 | 211,365 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2020 | 20,000 | 0 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2020 | 19,215 | 0 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.34 per share. | 15 Jun 2020 | 20,000 | 167,165 (0%) | 0% | 5.3 | 106,800 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Sale of securities on an exchange or to another person at price $ 44.00 per share. | 10 Jun 2020 | 785 | 127,950 (0%) | 0% | 44 | 34,540 | Common Stock |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Jun 2020 | 785 | 19,215 | - | - | Common Stock Options | |
| Hans-Martin Blickensdoerfer | Sr. VP, Comm. Ops, China | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.00 per share. | 10 Jun 2020 | 785 | 128,735 (0%) | 0% | 11 | 8,635 | Common Stock |
| Gilbert H. Kliman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2020 | 464 | 464 (0%) | 0% | 0 | Common Stock | |
| Thomas G. Frinzi | Director | 01 Jun 2020 | 971 | 971 | - | - | Common Stock Options | ||
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 13,333 | 6,667 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 5.34 per share. | 21 May 2020 | 20,000 | 61,185 (0%) | 0% | 5.3 | 106,800 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 7.35 per share. | 21 May 2020 | 20,000 | 81,185 (0%) | 0% | 7.4 | 147,000 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 7.52 per share. | 21 May 2020 | 20,000 | 101,185 (0%) | 0% | 7.5 | 150,400 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 9.30 per share. | 21 May 2020 | 21,875 | 123,060 (0%) | 0% | 9.3 | 203,438 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 11.02 per share. | 21 May 2020 | 50,000 | 173,060 (0%) | 0% | 11.0 | 551,000 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 11.02 per share. | 21 May 2020 | 20,000 | 193,060 (0%) | 0% | 11.0 | 220,400 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 15.54 per share. | 21 May 2020 | 12,500 | 205,560 (0%) | 0% | 15.5 | 194,250 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 16.50 per share. | 21 May 2020 | 13,333 | 218,893 (0%) | 0% | 16.5 | 219,995 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 29.80 per share. | 21 May 2020 | 6,292 | 225,185 (0%) | 0% | 29.8 | 187,502 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 35.98 per share. | 21 May 2020 | 8,522 | 233,707 (0%) | 0% | 36.0 | 306,622 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 21 May 2020 | 192,522 | 41,185 (0%) | 0% | 40 | 7,700,880 | Common Stock |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 20,000 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 20,000 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 20,000 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 21,875 | 625 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 50,000 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 20,000 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 12,500 | 0 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 6,292 | 4,495 | - | - | Common Stock Options | |
| Samuel Gesten | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 May 2020 | 8,522 | 14,374 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2020 | 25,000 | 0 | - | - | Common Stock Options | |
| Keith Holliday | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 37.69 per share. | 15 May 2020 | 25,000 | 28,447 (0%) | 0% | 37.7 | 942,250 | Common Stock |
| Keith Holliday | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.20 per share. | 15 May 2020 | 25,000 | 53,447 (0%) | 0% | 7.2 | 180,000 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2020 | 8,000 | 17,000 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.34 per share. | 11 May 2020 | 6,667 | 51,133 (0%) | 0% | 5.3 | 35,602 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Sale of securities on an exchange or to another person at price $ 39.06 per share. | 11 May 2020 | 18,856 | 44,466 (0%) | 0% | 39.1 | 736,515 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.35 per share. | 11 May 2020 | 8,000 | 52,466 (0%) | 0% | 7.4 | 58,800 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.54 per share. | 11 May 2020 | 10,856 | 63,322 (0%) | 0% | 15.5 | 168,702 | Common Stock |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2020 | 6,667 | 13,333 | - | - | Common Stock Options | |
| James E. Francese | Sr. VP, Comm. Ops., NA, APAC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2020 | 10,856 | 4,144 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 11 May 2020 | 6,741 | 22,763 (0%) | 0% | 9.3 | 62,691 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2020 | 8,680 | 3,820 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2020 | 4,862 | 2,431 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2020 | 6,741 | 0 | - | - | Common Stock Options | |
| Graydon. C. Hansen | Sr. VP, Global Operations | Sale of securities on an exchange or to another person at price $ 39.01 per share. | 11 May 2020 | 8,419 | 21,553 (0%) | 0% | 39.0 | 328,425 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 11 May 2020 | 8,680 | 29,972 (0%) | 0% | 16.2 | 140,182 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Sale of securities on an exchange or to another person at price $ 39.02 per share. | 11 May 2020 | 3,473 | 21,292 (0%) | 0% | 39.0 | 135,516 | Common Stock |
| Graydon. C. Hansen | Sr. VP, Global Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.25 per share. | 11 May 2020 | 4,862 | 24,765 (0%) | 0% | 15.3 | 74,146 | Common Stock |