53,651 XNAS Volume
XNAS 23 May, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 4,654,100 | 4,916,056 (5%) | 5% | 0 | Common Stock | |
| Kalayoglu Murat | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 228,000 | 228,000 | - | - | Stock Option (Right to Buy) | |
| Sallin Aymeric | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 228,000 | 228,000 | - | - | Stock Option (Right to Buy) | |
| Jewell Christopher M. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 778,200 | 778,200 (0%) | 0% | 0 | Common Stock | |
| Jewell M. Christopher | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 998,000 | 998,000 | - | - | Employee Stock Option (right to buy) | |
| Davis Blaine | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 3,110,000 | 3,110,000 | - | - | Employee Stock Option (right to buy) | |
| C. Timothy Barabe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 178,000 | 428,013 (0%) | 0% | 0 | Common Stock | |
| Zenner J. Patrick | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 228,000 | 228,000 | - | - | Stock Option (Right to Buy) | |
| S. Carrie Cox | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 248,000 | 248,000 | - | - | Stock Option (Right to Buy) | |
| Carrie Cox S. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 178,000 | 390,881 (0%) | 0% | 0 | Common Stock | |
| Sallin Aymeric | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 178,000 | 178,000 (0%) | 0% | 0 | Common Stock | |
| Kurtoglu Metin | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 1,531,000 | 1,531,000 (1%) | 1% | 0 | Common Stock | |
| Zenner Patrick J. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 178,000 | 233,248 (0%) | 0% | 0 | Common Stock | |
| Timothy Springer A. | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 228,000 | 228,000 | - | - | Stock Option (Right to Buy) | |
| Timothy Springer A. | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 178,000 | 7,471,625 (8%) | 0% | 0 | Common Stock | |
| Nishan de Silva | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 178,000 | 185,000 (0%) | 0% | 0 | Common Stock | |
| Milos Miljkovic | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 548,200 | 548,200 (0%) | 0% | 0 | Common Stock | |
| Kalayoglu Murat | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 178,000 | 435,739 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 5,971,000 | 5,971,000 | - | - | Employee Stock Option (right to buy) | |
| de Silva Nishan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 228,000 | 228,000 | - | - | Stock Option (Right to Buy) | |
| Barabe Timothy C. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 228,000 | 228,000 | - | - | Stock Option (Right to Buy) | |
| Davis Blaine | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 2,424,000 | 2,424,000 (2%) | 2% | 0 | Common Stock | |
| Kurtoglu Metin | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 1,965,000 | 1,965,000 | - | - | Employee Stock Option (right to buy) | |
| Miljkovic Milos | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 703,000 | 703,000 | - | - | Employee Stock Option (right to buy) | |
| Michael Singer | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Dec 2023 | 3,000 | 3,304 | - | - | Series A Convertible Preferred Stock | |
| Singer Michael | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Dec 2023 | 228,000 | 228,000 | - | - | Stock Option (Right to Buy) | |
| Michael Singer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Dec 2023 | 178,000 | 288,123 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 30 May 2023 | 43,000 | 321,316 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 30 May 2023 | 26,500 | 225,316 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 30 May 2023 | 26,500 | 251,816 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 30 May 2023 | 43,000 | 278,316 (0%) | 0% | 0 | Common Stock | |
| Peter G. Traber | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 3,445 | 446,141 (0%) | 0% | 1.1 | 3,890 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 8,164 | 449,601 (0%) | 0% | 1.1 | 9,256 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 15 | 449,586 (0%) | 0% | 1.1 | 17 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.10 per share. | 04 Jan 2023 | 20 | 446,121 (0%) | 0% | 1.1 | 22 | Common Stock |
| Lloyd Johnston | Chief Operations Officer | Sale of securities on an exchange or to another person at price $ 1.10 per share. | 04 Jan 2023 | 20 | 265,515 (0%) | 0% | 1.1 | 22 | Common Stock |
| Lloyd Johnston | Chief Operations Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 6,381 | 268,918 (0%) | 0% | 1.1 | 7,234 | Common Stock |
| Lloyd Johnston | Chief Operations Officer | Sale of securities on an exchange or to another person at price $ 1.18 per share. | 04 Jan 2023 | 11 | 268,907 (0%) | 0% | 1.2 | 13 | Common Stock |
| Lloyd Johnston | Chief Operations Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 3,372 | 265,535 (0%) | 0% | 1.1 | 3,808 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.18 per share. | 04 Jan 2023 | 11 | 367,708 (0%) | 0% | 1.2 | 13 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.10 per share. | 04 Jan 2023 | 20 | 364,316 (0%) | 0% | 1.1 | 22 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 6,381 | 367,719 (0%) | 0% | 1.1 | 7,234 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 3,372 | 364,336 (0%) | 0% | 1.1 | 3,808 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.12 per share. | 04 Jan 2023 | 77 | 786,013 (0%) | 0% | 1.1 | 86 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 27,549 | 799,534 (0%) | 0% | 1.1 | 31,232 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.15 per share. | 04 Jan 2023 | 48 | 799,486 (0%) | 0% | 1.1 | 55 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 04 Jan 2023 | 13,396 | 786,090 (0%) | 0% | 1.1 | 15,128 | Common Stock |
| Carrie S. Cox | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 107,500 | 107,500 | - | - | Stock Option (Right to Buy) | |
| Patrick J. Zenner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 200,000 | 457,765 (0%) | 0% | 0 | Common Stock | |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 900,000 | 900,000 | - | - | Employee Stock Option (right to buy) | |
| Scott D. Myers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 87,500 | 87,500 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 87,500 | 87,500 | - | - | Stock Option (Right to Buy) | |
| Nishan de Silva | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Johnston | Chief Operations Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 475,000 | 475,000 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | Chief Operations Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 100,000 | 275,299 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 100,000 | 374,100 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 475,000 | 475,000 | - | - | Employee Stock Option (right to buy) | |
| Aymeric Sallin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 282,800 | 827,083 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2023 | 1,275,000 | 1,275,000 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.33 per share. | 05 Dec 2022 | 4,522 | 544,283 (0%) | 0% | 1.3 | 6,014 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2022 | 10,938 | 0 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2022 | 10,938 | 548,805 (0%) | 0% | 0 | Common Stock | |
| Blaine Davis | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Nov 2022 | 1,250,000 | 1,250,000 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2022 | 10,937 | 545,327 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2022 | 10,937 | 10,938 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.85 per share. | 01 Sep 2022 | 4,768 | 540,559 (0%) | 0% | 1.8 | 8,810 | Common Stock |
| Carrie S. Cox | Director | Purchase of securities on an exchange or from another person at price $ 1.15 per share. | 13 Jun 2022 | 130,000 | 212,881 (0%) | 0% | 1.2 | 149,799 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2022 | 10,938 | 21,875 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2022 | 10,938 | 534,390 (0%) | 0% | 0 | Common Stock | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Apr 2022 | 5,011,200 | 5,011,200 | - | - | Warrant (right to buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 Apr 2022 | 6,681,600 | 29,868,490 (34%) | 7% | - | Common Stock | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.81 per share. | 01 Mar 2022 | 5,443 | 523,452 (0%) | 0% | 1.8 | 9,863 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2022 | 10,937 | 32,813 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2022 | 10,937 | 528,895 (0%) | 0% | 0 | Common Stock | |
| Timothy C. Barabe | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jan 2022 | 10,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.10 per share. | 14 Jan 2022 | 10,000 | 200,013 (0%) | 0% | 2.1 | 21,000 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 3.09 per share. | 05 Jan 2022 | 3,226 | 251,355 (0%) | 0% | 3.1 | 9,955 | Common Stock |
| Lloyd Johnston | Chief Operations Officer | Sale of securities on an exchange or to another person at price $ 3.09 per share. | 05 Jan 2022 | 3,416 | 175,299 (0%) | 0% | 3.1 | 10,541 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 3.09 per share. | 05 Jan 2022 | 3,416 | 268,353 (0%) | 0% | 3.1 | 10,541 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.09 per share. | 05 Jan 2022 | 13,597 | 517,958 (0%) | 0% | 3.1 | 41,959 | Common Stock |
| Carrie S. Cox | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| Patrick J. Zenner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 90,200 | 254,581 (0%) | 0% | 0 | Common Stock | |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 415,900 | 415,900 | - | - | Employee Stock Option (right to buy) | |
| Scott D. Myers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Nishan de Silva | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Johnston | Chief Operations Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 340,000 | 340,000 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | Chief Operations Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 72,000 | 178,715 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 340,000 | 340,000 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 72,000 | 271,769 (0%) | 0% | 0 | Common Stock | |
| Aymeric Sallin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 1,056,100 | 1,056,100 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 226,300 | 531,555 (0%) | 0% | 0 | Common Stock | |
| Kevin Tan | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 340,000 | 340,000 | - | - | Employee Stock Option (right to buy) | |
| Kevin Tan | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 72,000 | 77,000 (0%) | 0% | 0 | Common Stock | |
| Peter G. Traber | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.99 per share. | 10 Dec 2021 | 4,083 | 164,381 (0%) | 0% | 3.0 | 12,196 | Common Stock |
| Lloyd Johnston | Chief Operations Officer | Sale of securities on an exchange or to another person at price $ 2.99 per share. | 10 Dec 2021 | 4,370 | 106,715 (0%) | 0% | 3.0 | 13,053 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.99 per share. | 10 Dec 2021 | 4,370 | 199,769 (0%) | 0% | 3.0 | 13,053 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.99 per share. | 10 Dec 2021 | 17,196 | 305,255 (0%) | 0% | 3.0 | 51,363 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.99 per share. | 09 Dec 2021 | 58,681 | 22,961,108 (26%) | 0% | 3.0 | 175,439 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.06 per share. | 09 Dec 2021 | 3,748,000 | 22,902,427 (26%) | 4% | 3.1 | 11,468,880 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.98 per share. | 09 Dec 2021 | 14,592 | 22,975,700 (26%) | 0% | 3.0 | 43,491 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2021 | 13,750 | 168,464 (0%) | 0% | 0 | Common Stock | |
| Lloyd Johnston | Chief Operations Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2021 | 13,750 | 111,085 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2021 | 13,750 | 204,139 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2021 | 37,500 | 322,451 (0%) | 0% | 0 | Common Stock | |
| Carrie S. Cox | Director | Purchase of securities on an exchange or from another person at price $ 2.95 per share. | 03 Dec 2021 | 17,200 | 82,881 (0%) | 0% | 2.9 | 50,664 | Common Stock |
| Nishan de Silva | Director | Purchase of securities on an exchange or from another person at price $ 2.96 per share. | 02 Dec 2021 | 7,000 | 7,000 (0%) | 0% | 3.0 | 20,723 | Common Stock |
| Kevin Tan | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 3.03 per share. | 02 Dec 2021 | 5,000 | 5,000 (0%) | 0% | 3.0 | 15,127 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2021 | 10,938 | 289,697 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2021 | 10,938 | 43,750 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.96 per share. | 01 Dec 2021 | 4,746 | 284,951 (0%) | 0% | 3.0 | 14,065 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 4.39 per share. | 13 Oct 2021 | 3,636 | 154,714 (0%) | 0% | 4.4 | 15,962 | Common Stock |
| Lloyd Johnston | Chief Operations Officer | Sale of securities on an exchange or to another person at price $ 4.39 per share. | 13 Oct 2021 | 3,892 | 97,335 (0%) | 0% | 4.4 | 17,086 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 4.39 per share. | 13 Oct 2021 | 3,892 | 190,389 (0%) | 0% | 4.4 | 17,086 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.39 per share. | 13 Oct 2021 | 15,313 | 278,759 (0%) | 0% | 4.4 | 67,224 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2021 | 13,750 | 158,350 (0%) | 0% | 0 | Common Stock | |
| Lloyd Johnston | Chief Operations Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2021 | 13,750 | 101,227 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2021 | 13,750 | 194,281 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2021 | 37,500 | 294,072 (0%) | 0% | 0 | Common Stock | |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Sep 2021 | 9,100 | 144,600 (0%) | 0% | 0 | Common Stock | |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Sep 2021 | 54,400 | 54,400 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Sep 2021 | 27,200 | 256,572 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Sep 2021 | 163,000 | 163,000 | - | - | Employee Stock Option (right to buy) | |
| Kevin Tan | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Sep 2021 | 750,000 | 750,000 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.51 per share. | 01 Sep 2021 | 4,523 | 229,372 (0%) | 0% | 4.5 | 20,399 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 10,937 | 54,688 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 10,937 | 233,895 (0%) | 0% | 0 | Common Stock | |
| Timothy C. Barabe | Director | Purchase of securities on an exchange or from another person at price $ 4.00 per share. | 18 Aug 2021 | 9,000 | 190,013 (0%) | 0% | 4 | 36,000 | Common Stock |
| Nishan de Silva | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2021 | 80,000 | 80,000 | - | - | Stock Option (Right to Buy) | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.38 per share. | 01 Jun 2021 | 4,806 | 222,958 (0%) | 0% | 4.4 | 21,041 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 10,938 | 227,764 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 10,938 | 65,625 | - | - | Restricted Stock Units | |
| Peter G. Traber | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 3.99 per share. | 26 May 2021 | 20,000 | 135,500 (0%) | 0% | 4.0 | 79,850 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 3.32 per share. | 24 May 2021 | 12,500 | 110,500 (0%) | 0% | 3.3 | 41,498 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 3.48 per share. | 24 May 2021 | 5,000 | 115,500 (0%) | 0% | 3.5 | 17,400 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 4.00 per share. | 24 May 2021 | 926,170 | 19,154,427 (22%) | 1% | 4.0 | 3,705,699 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.55 per share. | 24 May 2021 | 383,830 | 18,228,257 (21%) | 0% | 3.5 | 1,362,098 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.38 per share. | 24 May 2021 | 590,000 | 17,844,427 (20%) | 0% | 3.4 | 1,992,076 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.19 per share. | 21 May 2021 | 2,773,479 | 17,254,427 (19%) | 3% | 3.2 | 8,847,398 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 May 2021 | 13,629 | 0 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.77 per share. | 07 May 2021 | 13,629 | 177,778 (0%) | 0% | 2.8 | 37,752 | Common Stock |
| Carrie S. Cox | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2021 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| Patrick J. Zenner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2021 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Scott D. Myers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2021 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2021 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Aymeric Sallin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2021 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2021 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | Director | Purchase of securities on an exchange or from another person at price $ 4.10 per share. | 26 Mar 2021 | 10,000 | 181,013 (0%) | 0% | 4.1 | 41,000 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 4.50 per share. | 17 Mar 2021 | 10,000 | 98,000 (0%) | 0% | 4.5 | 45,000 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 4.53 per share. | 17 Mar 2021 | 10,000 | 88,000 (0%) | 0% | 4.5 | 45,295 | Common Stock |
| Lloyd Johnston | COO and SVP, R&D | Sale of securities on an exchange or to another person at price $ 4.45 per share. | 17 Mar 2021 | 15,128 | 87,477 (0%) | 0% | 4.4 | 67,312 | Common Stock |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.26 per share. | 01 Mar 2021 | 5,461 | 216,826 (0%) | 0% | 4.3 | 23,257 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 10,937 | 76,563 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 10,937 | 222,287 (0%) | 0% | 0 | Common Stock | |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Feb 2021 | 44,871 | 0 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.63 per share. | 11 Feb 2021 | 44,871 | 102,605 (0%) | 0% | 0.6 | 28,269 | Common Stock |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 230,000 | 230,000 | - | - | Employee Stock Option (right to buy) | |
| Peter G. Traber | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 38,000 | 78,000 (0%) | 0% | 0 | Common Stock | |
| Lloyd Johnston | COO and SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 38,000 | 57,734 (0%) | 0% | 0 | Common Stock | |
| Lloyd Johnston | COO and SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 230,000 | 230,000 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 230,000 | 230,000 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 38,000 | 164,149 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 670,000 | 670,000 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 110,000 | 211,350 (0%) | 0% | 0 | Common Stock | |
| Bradford D. Dahms | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 230,000 | 230,000 | - | - | Employee Stock Option (right to buy) | |
| Bradford D. Dahms | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2021 | 38,000 | 38,000 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2020 | 10,938 | 87,500 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.35 per share. | 01 Dec 2020 | 3,323 | 101,350 (0%) | 0% | 3.4 | 11,134 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2020 | 10,938 | 104,673 (0%) | 0% | 0 | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.77 per share. | 23 Oct 2020 | 30,000 | 126,149 (0%) | 0% | 2.8 | 83,100 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Oct 2020 | 30,000 | 13,629 | - | - | Employee Stock Option (right to buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.63 per share. | 21 Oct 2020 | 1,770,204 | 13,486,460 (15%) | 2% | 2.6 | 4,656,699 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.71 per share. | 21 Oct 2020 | 994,488 | 14,480,948 (16%) | 1% | 2.7 | 2,699,737 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.50 per share. | 21 Oct 2020 | 880,000 | 11,716,256 (13%) | 1% | 2.5 | 2,199,472 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.36 per share. | 16 Oct 2020 | 759,500 | 9,926,256 (11%) | 0% | 2.4 | 1,795,002 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.21 per share. | 16 Oct 2020 | 910,000 | 10,836,256 (12%) | 1% | 2.2 | 2,013,193 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.42 per share. | 16 Oct 2020 | 218,196 | 9,166,756 (10%) | 0% | 2.4 | 528,034 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.00 per share. | 09 Oct 2020 | 276,703 | 8,948,560 (10%) | 0% | 2.0 | 552,465 | Common Stock |
| Timothy C. Barabe | Director | Purchase of securities on an exchange or from another person at price $ 1.68 per share. | 06 Oct 2020 | 50,000 | 171,013 (0%) | 0% | 1.7 | 83,985 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.89 per share. | 06 Oct 2020 | 530,441 | 8,671,857 (10%) | 0% | 1.9 | 1,000,836 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.65 per share. | 06 Oct 2020 | 654,953 | 8,141,416 (9%) | 0% | 1.6 | 1,078,577 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.68 per share. | 06 Oct 2020 | 2,000,000 | 7,486,463 (8%) | 2% | 1.7 | 3,365,800 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2020 | 10,937 | 97,099 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.39 per share. | 01 Sep 2020 | 3,364 | 93,735 (0%) | 0% | 2.4 | 8,035 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2020 | 10,937 | 98,438 | - | - | Restricted Stock Units | |
| Lloyd Johnston | COO & SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 40,000 | 40,000 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 75,000 | 75,000 | - | - | Employee Stock Option (right to buy) | |
| Bradford D. Dahms | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 40,000 | 40,000 | - | - | Employee Stock Option (right to buy) | |
| Timothy C. Barabe | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.46 per share. | 24 Jun 2020 | 32,840 | 121,013 (0%) | 0% | 1.5 | 47,946 | Common Stock |
| Timothy C. Barabe | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jun 2020 | 32,840 | 0 | - | - | Common Warrants | |
| Carrie S. Cox | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2020 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Patrick J. Zenner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Scott Myers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Aymeric Sallin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.86 per share. | 01 Jun 2020 | 3,253 | 86,162 (0%) | 0% | 3.9 | 12,557 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2020 | 10,938 | 109,375 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2020 | 10,938 | 89,415 (0%) | 0% | 0 | Common Stock | |
| Timothy C. Barabe | Director | Purchase of securities on an exchange or from another person at price $ 2.00 per share. | 17 Mar 2020 | 5,000 | 88,173 (0%) | 0% | 2 | 10,000 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2020 | 10,937 | 120,313 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.86 per share. | 01 Mar 2020 | 3,374 | 78,477 (0%) | 0% | 3.9 | 13,011 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2020 | 10,937 | 81,851 (0%) | 0% | 0 | Common Stock | |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.47 per share. | 16 Jan 2020 | 5,128 | 16,734 (0%) | 0% | 0.5 | 2,410 | Common Stock |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jan 2020 | 5,128 | 0 | - | - | Employee Stock Option (right to buy) | |
| Elona Kogan | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 140,000 | 140,000 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | COO and SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 140,000 | 140,000 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 140,000 | 140,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Smolinski | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 600,000 | 600,000 | - | - | Employee Stock Option (right to buy) | |
| Alison D. Schecter | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Bradford D. Dahms | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 140,000 | 140,000 | - | - | Employee Stock Option (right to buy) | |
| Carrie S. Cox | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Dec 2019 | 32,840 | 32,840 | - | - | Warrants | |
| Carrie S. Cox | None | Grant, award, or other acquisition of securities at price $ 1.46 per share. | 23 Dec 2019 | 65,681 | 65,681 (0%) | 0% | 1.5 | 95,894 | Common Stock |
| Scott Myers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Dec 2019 | 19,704 | 19,704 | - | - | Warrants | |
| Scott Myers | None | Grant, award, or other acquisition of securities at price $ 1.46 per share. | 23 Dec 2019 | 39,409 | 80,845 (0%) | 0% | 1.5 | 57,537 | Common Stock |
| Timothy C. Barabe | None | Grant, award, or other acquisition of securities at price $ 1.46 per share. | 23 Dec 2019 | 65,681 | 83,173 (0%) | 0% | 1.5 | 95,894 | Common Stock |
| Timothy C. Barabe | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Dec 2019 | 32,840 | 32,840 | - | - | Warrants | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Dec 2019 | 1,970,443 | 1,970,443 | - | - | Warrants | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 1.46 per share. | 23 Dec 2019 | 3,940,887 | 5,486,463 (6%) | 4% | 1.5 | 5,753,695 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 12 Dec 2019 | 1,237,028 | 7,293,625 (8%) | 2% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.53 per share. | 01 Dec 2019 | 14,272 | 70,914 (0%) | 0% | 1.5 | 21,809 | Common Stock |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2019 | 43,750 | 131,250 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2019 | 43,750 | 85,186 (0%) | 0% | 0 | Common Stock | |
| Carrie S. Cox | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Johnston | COO and SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Oct 2019 | 180,000 | 180,000 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Oct 2019 | 180,000 | 180,000 | - | - | Employee Stock Option (right to buy) | |
| Stephen Smolinski | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Oct 2019 | 180,000 | 180,000 | - | - | Employee Stock Option (right to buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Oct 2019 | 400,000 | 400,000 | - | - | Employee Stock Option (right to buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 03 Sep 2019 | 1,237,028 | 0 (0%) | 2% | 0 | Common Stock | |
| Bradford D. Dahms | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Sep 2019 | 400,000 | 400,000 | - | - | Employee Stock Option (right to buy) | |
| Patrick J. Zenner | None | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 55,248 | 55,248 (0%) | 0% | 1.8 | 99,999 | Common Stock |
| Scott Myers | None | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 41,436 | 41,436 (0%) | 0% | 1.8 | 74,999 | Common Stock |
| Elona Kogan | General Counsel | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 82,872 | 182,872 (0%) | 0% | 1.8 | 149,998 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 50,000 | 86,114 (0%) | 0% | 1.8 | 90,500 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 1,600,000 | 6,056,597 (7%) | 3% | 1.8 | 2,896,000 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 1,100,000 | 1,545,576 (1%) | 2% | 1.8 | 1,991,000 | Common Stock |
| Stephen Smolinski | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 13,812 | 13,812 (0%) | 0% | 1.8 | 25,000 | Common Stock |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 20 Aug 2019 | 41,436 | 41,436 (0%) | 0% | 1.8 | 74,999 | Common Stock |
| Timothy A. Springer | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.74 per share. | 14 Aug 2019 | 10,000 | 86,418 (0%) | 0% | 1.7 | 17,415 | Common Stock |
| Timothy C. Barabe | None | Purchase of securities on an exchange or from another person at price $ 1.72 per share. | 13 Aug 2019 | 10,000 | 17,492 (0%) | 0% | 1.7 | 17,200 | Common Stock |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Jul 2019 | 10,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.47 per share. | 23 Jul 2019 | 10,000 | 11,606 (0%) | 0% | 0.5 | 4,700 | Common Stock |
| Alison D. Schecter | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jul 2019 | 350,000 | 350,000 | - | - | Common Stock | |
| Patrick J. Zenner | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Scott Myers | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Amir H. Nashat | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Omid Farokhzad | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2019 | 15,404 | 15,404 | - | - | Stock Option (Right to Buy) | |
| Aymeric Sallin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Timothy A. Springer | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2019 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Elona Kogan | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Mar 2019 | 400,000 | 400,000 | - | - | Stock Option (Right to Buy) | |
| Elona Kogan | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Mar 2019 | 100,000 | 100,000 (0%) | 0% | 0 | Common Stock | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2019 | 330,000 | 330,000 | - | - | Employee Stock Option (right to buy) | |
| Amir H. Nashat | None | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 25 Jan 2019 | 7,711 | 18,329 (0%) | 0% | 1.5 | 11,567 | Common Stock |
| Amir H. Nashat | None | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 25 Jan 2019 | 1,125,756 | 2,676,234 (3%) | 5% | 1.5 | 1,688,634 | Common Stock |
| Amir H. Nashat | None | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 25 Jan 2019 | 11,258 | 26,760 (0%) | 0% | 1.5 | 16,887 | Common Stock |
| Amir H. Nashat | None | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 25 Jan 2019 | 21,941 | 52,156 (0%) | 0% | 1.5 | 32,912 | Common Stock |
| Lloyd Johnston | COO and SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.77 per share. | 07 Jan 2019 | 36,114 | 36,114 (0%) | 0% | 2.8 | 100,036 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Jan 2019 | 36,114 | 43,629 | - | - | Employee Stock Option (right to buy) | |
| Stephen Smolinski | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| Omid Farokhzad | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2018 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2018 | 175,000 | 175,000 | - | - | Restricted Stock Units | |
| Carsten Brunn | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2018 | 1,000,000 | 1,000,000 | - | - | Stock Option (Right to Buy) | |
| Patrick J. Zenner | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Peter Barton Hutt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Amir H. Nashat | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| John H. Leaman | CFO, Treas. & Hd Corp Strategy | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Omid Farokhzad | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 15,404 | 15,404 | - | - | Stock Option (Right to Buy) | |
| Lloyd Johnston | COO and SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| David Abraham | GC, CCO & Corporate Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Aymeric Sallin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Timothy A. Springer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Stephen Smolinski | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 80,000 | 80,000 | - | - | Stock Option (Right to Buy) | |
| Omid Farokhzad | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 May 2018 | 95,000 | 95,000 | - | - | Stock Option (Right to Buy) | |
| John H. Leaman | CFO, Treas. & Hd Corp Strategy | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2017 | 220,000 | 220,000 | - | - | Stock Option (right to buy) | |
| Earl Sands | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 10.26 per share. | 17 Nov 2017 | 7,500 | 7,500 (0%) | 0% | 10.3 | 76,967 | Common Stock |
| Stephen Smolinski | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2017 | 80,000 | 80,000 | - | - | Stock Option (right to buy) | |
| David Abraham | GC, CCO & Corporate Secretary | Purchase of securities on an exchange or from another person at price $ 9.25 per share. | 14 Nov 2017 | 5,405 | 5,405 (0%) | 0% | 9.2 | 49,996 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 9.27 per share. | 14 Nov 2017 | 57,598 | 461,349 (2%) | 0% | 9.3 | 534,095 | Common Stock |
| Werner Cautreels | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 9.31 per share. | 13 Nov 2017 | 20,000 | 321,203 (1%) | 0% | 9.3 | 186,250 | Common Stock |
| Timothy C. Barabe | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 09 Nov 2017 | 2,500 | 7,492 (0%) | 0% | 9.0 | 22,505 | Common Stock |
| Timothy C. Barabe | None | Purchase of securities on an exchange or from another person at price $ 9.73 per share. | 09 Nov 2017 | 2,500 | 4,992 (0%) | 0% | 9.7 | 24,335 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 9.78 per share. | 09 Nov 2017 | 100 | 5,000 (0%) | 0% | 9.8 | 978 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 9.33 per share. | 09 Nov 2017 | 4,900 | 4,900 (0%) | 0% | 9.3 | 45,703 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 9.74 per share. | 09 Nov 2017 | 900 | 377,413 (1%) | 0% | 9.7 | 8,767 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 9.33 per share. | 09 Nov 2017 | 21,100 | 376,513 (1%) | 0% | 9.3 | 196,893 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 9.03 per share. | 09 Nov 2017 | 4,752 | 403,751 (1%) | 0% | 9.0 | 42,906 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 9.04 per share. | 09 Nov 2017 | 21,586 | 398,999 (1%) | 0% | 9.0 | 195,191 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 26 Sep 2017 | 1,321 | 30,215 (0%) | 0% | 18.9 | 24,982 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 26 Sep 2017 | 67,764 | 1,550,478 (7%) | 0% | 18.9 | 1,281,519 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 26 Sep 2017 | 677 | 15,502 (0%) | 0% | 18.9 | 12,803 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 26 Sep 2017 | 464 | 10,618 (0%) | 0% | 18.9 | 8,775 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.99 per share. | 22 Sep 2017 | 35,872 | 1,618,242 (7%) | 0% | 19.0 | 681,141 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.99 per share. | 22 Sep 2017 | 359 | 16,179 (0%) | 0% | 19.0 | 6,817 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.26 per share. | 22 Sep 2017 | 278 | 11,327 (0%) | 0% | 19.3 | 5,355 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.26 per share. | 22 Sep 2017 | 406 | 16,538 (0%) | 0% | 19.3 | 7,821 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.26 per share. | 22 Sep 2017 | 40,562 | 1,654,114 (7%) | 0% | 19.3 | 781,386 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.99 per share. | 22 Sep 2017 | 699 | 31,536 (0%) | 0% | 19.0 | 13,273 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 18.99 per share. | 22 Sep 2017 | 245 | 11,082 (0%) | 0% | 19.0 | 4,652 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.26 per share. | 22 Sep 2017 | 790 | 32,235 (0%) | 0% | 19.3 | 15,218 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 20.03 per share. | 20 Sep 2017 | 282 | 12,295 (0%) | 0% | 20.0 | 5,648 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 20.03 per share. | 20 Sep 2017 | 801 | 34,992 (0%) | 0% | 20.0 | 16,042 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.86 per share. | 20 Sep 2017 | 100,911 | 1,694,676 (7%) | 0% | 19.9 | 2,004,022 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.86 per share. | 20 Sep 2017 | 1,009 | 16,944 (0%) | 0% | 19.9 | 20,038 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.86 per share. | 20 Sep 2017 | 690 | 11,605 (0%) | 0% | 19.9 | 13,703 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 19.86 per share. | 20 Sep 2017 | 1,967 | 33,025 (0%) | 0% | 19.9 | 39,063 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 20.03 per share. | 20 Sep 2017 | 41,116 | 1,795,587 (8%) | 0% | 20.0 | 823,467 | Common Stock |
| Amir H. Nashat | None | Sale of securities on an exchange or to another person at price $ 20.03 per share. | 20 Sep 2017 | 411 | 17,953 (0%) | 0% | 20.0 | 8,232 | Common Stock |
| David Siewers | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Sep 2017 | 14,230 | 5,000 | - | - | Employee Stock Option (right to buy) | |
| David Siewers | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.63 per share. | 20 Sep 2017 | 14,230 | 14,230 (0%) | 0% | 0.6 | 8,965 | Common Stock |
| David Siewers | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 20 Sep 2017 | 2,194 | 0 (0%) | 0% | 20 | 43,880 | Common Stock |
| David Siewers | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.63 per share. | 20 Sep 2017 | 2,194 | 2,194 (0%) | 0% | 0.6 | 1,382 | Common Stock |
| David Siewers | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 20 Sep 2017 | 14,230 | 0 (0%) | 0% | 20 | 284,600 | Common Stock |
| David Siewers | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Sep 2017 | 2,194 | 0 | - | - | Employee Stock Option (right to buy) | |
| Werner Cautreels | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Earl Sands | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 35,000 | 35,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Johnston | COO & Senior VP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 45,000 | 45,000 | - | - | Stock Option (Right to Buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Peter Keller | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 32,000 | 32,000 | - | - | Stock Option (Right to Buy) | |
| David Abraham | GC and Corporate Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| David Siewers | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Johnston | COO and SVP, R*D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jul 2017 | 5,959 | 126 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | COO and SVP, R*D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.77 per share. | 03 Jul 2017 | 5,959 | 7,565 (0%) | 0% | 2.8 | 16,506 | Common Stock |
| Lloyd Johnston | COO and SVP, R*D | Sale of securities on an exchange or to another person at price $ 19.74 per share. | 03 Jul 2017 | 100 | 7,465 (0%) | 0% | 19.7 | 1,974 | Common Stock |
| Lloyd Johnston | COO and SVP, R*D | Sale of securities on an exchange or to another person at price $ 19.09 per share. | 03 Jul 2017 | 5,859 | 1,606 (0%) | 0% | 19.1 | 111,832 | Common Stock |
| David Siewers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 30 Jun 2017 | 7,420 | 0 (0%) | 0% | 20.0 | 148,405 | Common Stock |
| David Siewers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.63 per share. | 30 Jun 2017 | 7,420 | 7,420 (0%) | 0% | 0.6 | 4,675 | Common Stock |
| David Siewers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2017 | 7,420 | 2,194 | - | - | Employee Stock Option (right to buy) | |
| David Siewers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jun 2017 | 5,770 | 9,614 | - | - | Employee Stock Option (right to buy) | |
| David Siewers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.63 per share. | 29 Jun 2017 | 5,770 | 9,652 (0%) | 0% | 0.6 | 3,635 | Common Stock |
| David Siewers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 29 Jun 2017 | 9,616 | 36 (0%) | 0% | 20.0 | 192,322 | Common Stock |
| David Siewers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 29 Jun 2017 | 36 | 0 (0%) | 0% | 20 | 720 | Common Stock |
| David Siewers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jun 2017 | 3,846 | 0 | - | - | Employee Stock Option (right to buy) | |
| David Siewers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.47 per share. | 29 Jun 2017 | 3,846 | 3,882 (0%) | 0% | 0.5 | 1,808 | Common Stock |
| Peter Keller | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.63 per share. | 27 Jun 2017 | 4,595 | 5,000 (0%) | 0% | 0.6 | 2,895 | Common Stock |
| Peter Keller | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jun 2017 | 4,595 | 89,588 | - | - | Employee Stock Option (right to buy) | |
| Peter Keller | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 19.30 per share. | 27 Jun 2017 | 4,595 | 405 (0%) | 0% | 19.3 | 88,681 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jun 2017 | 79,130 | 79,130 | - | - | Warrant (right to buy) | |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 17.71 per share. | 27 Jun 2017 | 338,791 | 355,413 (1%) | 1% | 17.7 | 5,999,989 | Common Stock |
| David Siewers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 26 Jun 2017 | 6,886 | 36 (0%) | 0% | 20 | 137,720 | Common Stock |
| Patrick J. Zenner | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2017 | 12,820 | 12,820 | - | - | Stock Option (Right to Buy) | |
| Peter Barton Hutt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2017 | 6,410 | 6,410 | - | - | Stock Option (Right to Buy) | |
| Timothy C. Barabe | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2017 | 6,410 | 6,410 | - | - | Stock Option (Right to Buy) | |
| Amir H. Nashat | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2017 | 6,410 | 6,410 | - | - | Stock Option (Right to Buy) | |
| Omid Farokhzad | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2017 | 6,410 | 6,410 | - | - | Stock Option (Right to Buy) | |
| Aymeric Sallin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2017 | 6,410 | 6,410 | - | - | Stock Option (Right to Buy) | |
| Timothy A. Springer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2017 | 6,410 | 6,410 | - | - | Stock Option (Right to Buy) | |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2017 | 10,512 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | COO and SVP, R&D | Sale of securities on an exchange or to another person at price $ 17.04 per share. | 15 Jun 2017 | 10,512 | 1,606 (0%) | 0% | 17.0 | 179,141 | Common Stock |
| Lloyd Johnston | COO and SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.47 per share. | 15 Jun 2017 | 10,512 | 12,118 (0%) | 0% | 0.5 | 4,941 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 13.75 per share. | 01 Jun 2017 | 518 | 16,622 (0%) | 0% | 13.8 | 7,123 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 14.01 per share. | 17 May 2017 | 11,244 | 11,244 (0%) | 0% | 14.0 | 157,483 | Common Stock |
| Timothy A. Springer | None | Purchase of securities on an exchange or from another person at price $ 14.00 per share. | 17 May 2017 | 4,860 | 16,104 (0%) | 0% | 14 | 68,040 | Common Stock |
| Edwin M. Kania | None | Sale of securities on an exchange or to another person at price $ 14.00 per share. | 16 May 2017 | 266,795 | 560,067 (3%) | 1% | 14 | 3,735,130 | Common Stock |
| Lloyd Johnston | COO AND SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.39 per share. | 17 Apr 2017 | 13,205 | 14,811 (0%) | 0% | 0.4 | 5,150 | Common Stock |
| Lloyd Johnston | COO AND SVP, R&D | Sale of securities on an exchange or to another person at price $ 13.95 per share. | 17 Apr 2017 | 13,205 | 1,606 (0%) | 0% | 14.0 | 184,210 | Common Stock |
| Lloyd Johnston | COO AND SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Apr 2017 | 13,205 | 0 | - | - | Employee Stock Option (right to buy) | |
| Timothy C. Barabe | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.00 per share. | 27 Mar 2017 | 2,492 | 2,492 (0%) | 0% | 11 | 27,412 | Common Stock |
| Timothy C. Barabe | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Mar 2017 | 2,492 | 10,328 | - | - | Stock Option (Right to Buy) | |
| Omid Farokhzad | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Mar 2017 | 51,981 | 9,932 | - | - | Stock Option (right to buy) | |
| Omid Farokhzad | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.02 per share. | 23 Mar 2017 | 8,019 | 188,004 (1%) | 0% | 7.0 | 56,293 | Common Stock |
| Omid Farokhzad | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.44 per share. | 23 Mar 2017 | 51,981 | 179,985 (0%) | 0% | 3.4 | 178,815 | Common Stock |
| Omid Farokhzad | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Mar 2017 | 8,019 | 17,622 | - | - | Stock Option (right to buy) | |
| Lloyd Johnston | COO AND SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.39 per share. | 23 Jan 2017 | 15,000 | 16,606 (0%) | 0% | 0.4 | 5,850 | Common Stock |
| Lloyd Johnston | COO AND SVP, R&D | Sale of securities on an exchange or to another person at price $ 14.17 per share. | 23 Jan 2017 | 3,890 | 1,606 (0%) | 0% | 14.2 | 55,121 | Common Stock |
| Lloyd Johnston | COO AND SVP, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Jan 2017 | 15,000 | 13,205 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | COO AND SVP, R&D | Sale of securities on an exchange or to another person at price $ 13.95 per share. | 23 Jan 2017 | 11,110 | 5,496 (0%) | 0% | 14.0 | 154,985 | Common Stock |
| Takashi Kei Kishimoto | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Dec 2016 | 10,000 | 0 | - | - | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Dec 2016 | 10,000 | 10,000 | - | - | Common Stock | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Dec 2016 | 10,000 | 79,743 | - | - | Employee Stock Option (right to buy) | |
| David Abraham | CCO, Gen.Counsel, Corp.Sec. | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 21 Dec 2016 | 14,844 | 0 | - | - | Common Stock | |
| David Abraham | CCO, Gen.Counsel, Corp.Sec. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Dec 2016 | 12,280 | 540 | - | - | Employee Stock Option (right to buy) | |
| David Abraham | CCO, Gen.Counsel, Corp.Sec. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Dec 2016 | 12,280 | 14,844 | - | - | Common Stock | |
| Peter Keller | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Dec 2016 | 4,723 | 405 | - | - | Common Stock | |
| Timothy C. Barabe | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2016 | 12,820 | 12,820 | - | - | Stock Option (Right to Buy) | |
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 380,986 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 4,351 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 3,628 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 456,870 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 77,697 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Carl L Gordon | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jun 2016 | 544,811 | 1,825,415 | - | - | Common Stock | |
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 11,111 | 12,193 | - | - | Common Stock | ||
| Carl L Gordon | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jun 2016 | 5,189 | 17,382 | - | - | Common Stock | |
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 1,166,884 | 1,280,604 | - | - | Common Stock | ||
| Carl L Gordon | Director, Ten Percent Owner | 27 Jun 2016 | 739 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 631,458 | 981,325 | - | - | Common Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 193,777 | 1,651,862 | - | - | Common Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 241,718 | 1,458,085 | - | - | Common Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 235,042 | 1,216,367 | - | - | Common Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 318,752 | 349,867 | - | - | Common Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 125,008 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 241,718 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 235,042 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 631,458 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Edwin M. Kania | None | 27 Jun 2016 | 318,752 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 11,318 | 11,586 | - | - | Common Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 1,652,646 | 1,691,963 | - | - | Common Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 1,082 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 3,078 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 238,470 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 2,384 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 1,632 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 4,647 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 226,801 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 2,267 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 1,553 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 4,420 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 609,316 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 6,093 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 4,174 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 11,875 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 333,207 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 32,207 | 32,972 | - | - | Common Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 16,524 | 16,916 | - | - | Common Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jun 2016 | 2,821 | 35,793 | - | - | Common Stock | |
| Amir H. Nashat | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jun 2016 | 991 | 12,577 | - | - | Common Stock | |
| Amir H. Nashat | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jun 2016 | 1,448 | 18,364 | - | - | Common Stock | |
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 3,332 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 2,282 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 6,494 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jun 2016 | 144,740 | 1,836,703 | - | - | Common Stock | |
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 157,957 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Amir H. Nashat | Director, Ten Percent Owner | 27 Jun 2016 | 1,579 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Omid Farokhzad | None | 27 Jun 2016 | 22,081 | 25,626 | - | - | Common Stock | ||
| Omid Farokhzad | None | 27 Jun 2016 | 14,244 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Werner Cautreels | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2016 | 115,384 | 115,384 | - | - | Stock Option (right to buy) | |
| Earl Sands | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2016 | 53,999 | 53,999 | - | - | Employee Stock Option (right to buy) | |
| Lloyd Johnston | COO and SVP, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2016 | 27,617 | 27,617 | - | - | Employee Stock Option (right to buy) | |
| Takashi Kei Kishimoto | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2016 | 24,512 | 24,512 | - | - | Employee Stock Option (right to buy) | |
| Peter Keller | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2016 | 30,841 | 30,841 | - | - | Employee Stock Option (right to buy) | |
| David Abraham | CCO, GC and Corp. Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2016 | 28,760 | 28,760 | - | - | Employee Stock Option (right to buy) | |
| David Siewers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2016 | 33,888 | 33,888 | - | - | Employee Stock Option (right to buy) |