638.6K XNYS Volume
XNYS 18 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 10.18 per share. | 27 Feb 2025 | 19,800 | 2,554,160 (5%) | 0% | 10.2 | 201,465 | Common Stock |
| Yasunori Kaneko | Director | Purchase of securities on an exchange or from another person at price $ 10.06 per share. | 27 Feb 2025 | 20,000 | 28,400 (0%) | 0% | 10.1 | 201,200 | Common Stock |
| Richard Markus | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 305,328 | 305,328 | - | - | Stock Option (right to buy) | |
| Richard Markus | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 75,193 | 75,193 (0%) | 0% | 0 | Common Stock | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 650,000 | 650,000 | - | - | Stock Option (right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 165,000 | 2,534,360 (5%) | 0% | 0 | Common Stock | |
| Juan Carlos Jaen | President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| Juan Carlos Jaen | President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 50,000 | 367,220 (0%) | 0% | 0 | Common Stock | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 37,000 | 97,138 (0%) | 0% | 0 | Common Stock | |
| Jennifer Ann Jarrett | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 50,000 | 213,369 (0%) | 0% | 0 | Common Stock | |
| Jennifer Ann Jarrett | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Alexander Azoy | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 17,100 | 30,194 (0%) | 0% | 0 | Common Stock | |
| Alexander Azoy | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 11,400 | 11,400 | - | - | Stock Option (right to buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 37,000 | 137,623 (0%) | 0% | 0 | Common Stock | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2025 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 15.00 per share. | 31 Dec 2024 | 3,594 | 60,138 (0%) | 0% | 15 | 53,910 | Common Stock |
| Azoy Alexander | Chief Accounting Officer | Sale or transfer of securities back to the company at price $ 15.17 per share. | 19 Dec 2024 | 3,007 | 13,094 (0%) | 0% | 15.2 | 45,616 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.08 per share. | 15 Dec 2024 | 37,882 | 2,369,360 (5%) | 0% | 16.1 | 609,143 | Common Stock |
| Juan Carlos Jaen | President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.08 per share. | 15 Dec 2024 | 17,286 | 317,220 (0%) | 0% | 16.1 | 277,959 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.08 per share. | 15 Dec 2024 | 10,099 | 63,732 (0%) | 0% | 16.1 | 162,392 | Common Stock |
| Jennifer Ann Jarrett | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.08 per share. | 15 Dec 2024 | 27,501 | 163,369 (0%) | 0% | 16.1 | 442,216 | Common Stock |
| Alexander Azoy | Chief Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.08 per share. | 15 Dec 2024 | 2,969 | 16,101 (0%) | 0% | 16.1 | 47,742 | Common Stock |
| Dimitry SA Nuyten | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.08 per share. | 15 Dec 2024 | 7,856 | 87,518 (0%) | 0% | 16.1 | 126,324 | Common Stock |
| Carolyn C. Tang | General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.08 per share. | 15 Dec 2024 | 11,339 | 100,623 (0%) | 0% | 16.1 | 182,331 | Common Stock |
| Alexander Azoy | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 15.32 per share. | 02 Dec 2024 | 201 | 19,070 (0%) | 0% | 15.3 | 3,079 | Common Stock |
| Jennifer Ann Jarrett | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.95 per share. | 15 Sep 2024 | 12,670 | 190,394 (0%) | 0% | 18.0 | 227,427 | Common Stock |
| Dimitry SA Nuyten | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.95 per share. | 15 Sep 2024 | 5,385 | 94,933 (0%) | 0% | 18.0 | 96,661 | Common Stock |
| Alexander Azoy | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 14.97 per share. | 13 Aug 2024 | 1,357 | 19,070 (0%) | 0% | 15.0 | 20,314 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.97 per share. | 15 Jun 2024 | 12,670 | 3,954,304 (8%) | 0% | 17.0 | 215,010 | Common Stock |
| Juan Carlos Jaen | President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.97 per share. | 15 Jun 2024 | 6,969 | 334,506 (0%) | 0% | 17.0 | 118,264 | Common Stock |
| Jennifer Ann Jarrett | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.97 per share. | 15 Jun 2024 | 12,670 | 203,064 (0%) | 0% | 17.0 | 215,010 | Common Stock |
| Carolyn C. Tang | General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.97 per share. | 15 Jun 2024 | 4,182 | 111,364 (0%) | 0% | 17.0 | 70,969 | Common Stock |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 8,400 | 25,300 (0%) | 0% | 0 | Common Stock | |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 24,000 | 24,000 | - | - | Stock Option (Right to Buy) | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 8,400 | 55,300 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 24,000 | 24,000 | - | - | Stock Option (Right to Buy) | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 24,000 | 24,000 | - | - | Stock Option (Right to Buy) | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 8,400 | 29,325 (0%) | 0% | 0 | Common Stock | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 24,000 | 24,000 | - | - | Stock Option (Right to Buy) | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 8,400 | 57,652 (0%) | 0% | 0 | Common Stock | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 24,000 | 24,000 | - | - | Stock Option (Right to Buy) | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 8,400 | 15,200 (0%) | 0% | 0 | Common Stock | |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 24,000 | 24,000 | - | - | Stock Option (Right to Buy) | |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 8,400 | 24,000 (0%) | 0% | 0 | Common Stock | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 24,000 | 24,000 | - | - | Stock Option (Right to Buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2024 | 8,400 | 30,350 (0%) | 0% | 0 | Common Stock | |
| Jennifer Ann Jarrett | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 17.55 per share. | 27 Mar 2024 | 11,551 | 215,253 (0%) | 0% | 17.5 | 202,720 | Common Stock |
| Jennifer Ann Jarrett | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 17.84 per share. | 18 Mar 2024 | 12,153 | 228,100 (0%) | 0% | 17.8 | 216,810 | Common Stock |
| Jennifer Ann Jarrett | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 18.62 per share. | 18 Mar 2024 | 1,296 | 226,804 (0%) | 0% | 18.6 | 24,132 | Common Stock |
| Ann Jennifer Jarrett | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 20.07 per share. | 26 Feb 2024 | 24,555 | 274,323 (0%) | 0% | 20.1 | 492,819 | Common Stock |
| Jennifer Jarrett Ann | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 20.11 per share. | 26 Feb 2024 | 34,070 | 240,253 (0%) | 0% | 20.1 | 685,148 | Common Stock |
| Juan Carlos Jaen | President | Sale of securities on an exchange or to another person at price $ 20.10 per share. | 26 Feb 2024 | 23,132 | 1,188,233 (2%) | 0% | 20.1 | 464,953 | Common Stock |
| Juan Jaen Carlos | President | Sale of securities on an exchange or to another person at price $ 20.06 per share. | 26 Feb 2024 | 3,900 | 1,211,365 (2%) | 0% | 20.1 | 78,234 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 40,000 | 298,878 (0%) | 0% | 0 | Common Stock | |
| Azoy Alexander | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 8,850 | 19,070 (0%) | 0% | 0 | Common Stock | |
| Juan Jaen Carlos | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 40,000 | 341,475 (0%) | 0% | 0 | Common Stock | |
| Carolyn Tang C. | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 26,700 | 114,579 (0%) | 0% | 0 | Common Stock | |
| Nuyten SA Dimitry | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 28,000 | 99,195 (0%) | 0% | 0 | Common Stock | |
| Tang Carolyn C. | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 108,200 | 108,200 | - | - | Stock Option (right to buy) | |
| Goeltz Robert C. | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 21,300 | 73,131 (0%) | 0% | 0 | Common Stock | |
| Carlos Juan Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 162,400 | 162,400 | - | - | Stock Option (right to buy) | |
| SA Dimitry Nuyten | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 113,700 | 113,700 | - | - | Stock Option (right to buy) | |
| Goeltz Robert C. | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 86,600 | 86,600 | - | - | Stock Option (right to buy) | |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 162,400 | 162,400 | - | - | Stock Option (right to buy) | |
| Rosen Terry | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 405,900 | 405,900 | - | - | Stock Option (right to buy) | |
| Azoy Alexander | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 5,900 | 5,900 | - | - | Stock Option (right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 100,000 | 3,966,974 (8%) | 0% | 0 | Common Stock | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2024 | 22,000 | 73,831 (0%) | 0% | 0 | Common Stock | |
| Carlos Juan Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 20.09 per share. | 02 Jan 2024 | 6,975 | 1,215,265 (2%) | 0% | 20.1 | 140,128 | Common Stock |
| Robert Goeltz C. | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 02 Jan 2024 | 2,004 | 51,831 (0%) | 0% | 20 | 40,080 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | 29 Dec 2023 | 448 | 3,866,974 (8%) | 0% | 0 | Common Stock | ||
| Jarrett Ann Jennifer | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 17.76 per share. | 22 Dec 2023 | 21,521 | 258,878 (0%) | 0% | 17.8 | 382,213 | Common Stock |
| Azoy Alexander | Chief Accounting Officer | Sale or transfer of securities back to the company at price $ 18.21 per share. | 20 Dec 2023 | 68 | 10,220 (0%) | 0% | 18.2 | 1,238 | Common Stock |
| Azoy Alexander | Chief Accounting Officer | Sale or transfer of securities back to the company at price $ 17.74 per share. | 18 Dec 2023 | 647 | 10,949 (0%) | 0% | 17.7 | 11,478 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 17.74 per share. | 18 Dec 2023 | 13,705 | 3,880,526 (8%) | 0% | 17.7 | 243,127 | Common Stock |
| Carolyn Tang C. | General Counsel | Sale or transfer of securities back to the company at price $ 18.09 per share. | 18 Dec 2023 | 4,076 | 87,879 (0%) | 0% | 18.1 | 73,735 | Common Stock |
| Carlos Juan Jaen | Director, President | Sale or transfer of securities back to the company at price $ 17.74 per share. | 18 Dec 2023 | 6,128 | 307,734 (0%) | 0% | 17.7 | 108,711 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 18.09 per share. | 18 Dec 2023 | 14,000 | 3,866,526 (8%) | 0% | 18.1 | 253,260 | Common Stock |
| Dimitry Nuyten SA | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 18.09 per share. | 18 Dec 2023 | 1,540 | 71,195 (0%) | 0% | 18.1 | 27,859 | Common Stock |
| Dimitry SA Nuyten | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 17.74 per share. | 18 Dec 2023 | 1,507 | 72,735 (0%) | 0% | 17.7 | 26,734 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 17.74 per share. | 18 Dec 2023 | 2,749 | 56,643 (0%) | 0% | 17.7 | 48,767 | Common Stock |
| Ann Jarrett Jennifer | Director, Chief Operating Officer | Sale or transfer of securities back to the company at price $ 18.09 per share. | 18 Dec 2023 | 11,492 | 280,399 (0%) | 0% | 18.1 | 207,890 | Common Stock |
| C. Carolyn Tang | General Counsel | Sale or transfer of securities back to the company at price $ 17.74 per share. | 18 Dec 2023 | 3,991 | 91,955 (0%) | 0% | 17.7 | 70,800 | Common Stock |
| Carlos Juan Jaen | Director, President | Sale or transfer of securities back to the company at price $ 18.09 per share. | 18 Dec 2023 | 6,259 | 301,475 (0%) | 0% | 18.1 | 113,225 | Common Stock |
| Azoy Alexander | Chief Accounting Officer | Sale or transfer of securities back to the company at price $ 18.09 per share. | 18 Dec 2023 | 661 | 10,288 (0%) | 0% | 18.1 | 11,957 | Common Stock |
| Goeltz C. Robert | Chief Financial Officer | Sale or transfer of securities back to the company at price $ 18.09 per share. | 18 Dec 2023 | 2,808 | 53,835 (0%) | 0% | 18.1 | 50,797 | Common Stock |
| Ann Jennifer Jarrett | Director, Chief Operating Officer | Sale or transfer of securities back to the company at price $ 17.74 per share. | 18 Dec 2023 | 11,250 | 291,891 (0%) | 0% | 17.7 | 199,575 | Common Stock |
| Alexander Azoy | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 14.95 per share. | 01 Dec 2023 | 282 | 11,596 (0%) | 0% | 15.0 | 4,216 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 19.99 per share. | 22 Sep 2023 | 21,369 | 302,691 (0%) | 0% | 20.0 | 427,166 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale or transfer of securities back to the company at price $ 20.40 per share. | 18 Sep 2023 | 12,506 | 324,060 (0%) | 0% | 20.4 | 255,122 | Common Stock |
| Dimitry SA Nuyten | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 20.40 per share. | 18 Sep 2023 | 3,708 | 73,591 (0%) | 0% | 20.4 | 75,643 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 20.25 per share. | 28 Jul 2023 | 45,000 | 336,566 (0%) | 0% | 20.3 | 911,250 | Common Stock |
| Alexander Azoy | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 20.41 per share. | 03 Jul 2023 | 1,018 | 11,596 (0%) | 0% | 20.4 | 20,777 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 19.12 per share. | 22 Jun 2023 | 12,437 | 381,566 (0%) | 0% | 19.1 | 237,795 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 19.35 per share. | 16 Jun 2023 | 8,762 | 3,894,231 (8%) | 0% | 19.4 | 169,545 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 19.35 per share. | 16 Jun 2023 | 12,563 | 394,003 (0%) | 0% | 19.3 | 243,094 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale or transfer of securities back to the company at price $ 19.35 per share. | 16 Jun 2023 | 2,892 | 95,902 (0%) | 0% | 19.3 | 55,960 | Common Stock |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 19,500 | 19,500 | - | - | Stock Option (Right to Buy) | |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 6,800 | 16,900 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 19,500 | 19,500 | - | - | Stock Option (Right to Buy) | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 6,800 | 46,900 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 15 Jun 2023 | 50,504 | 40,100 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 19,500 | 19,500 | - | - | Stock Option (Right to Buy) | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 6,800 | 20,925 (0%) | 0% | 0 | Common Stock | |
| Juan Carlos Jaen | Director, President | Sale or transfer of securities back to the company at price $ 19.35 per share. | 15 Jun 2023 | 4,820 | 313,862 (0%) | 0% | 19.4 | 93,267 | Common Stock |
| Juan Carlos Jaen | Director, President | Gift of securities by or to the insider at price $ 0.00 per share. | 15 Jun 2023 | 6,000 | 318,682 (0%) | 0% | 0 | Common Stock | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 19,500 | 19,500 | - | - | Stock Option (Right to Buy) | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 6,800 | 49,252 (0%) | 0% | 0 | Common Stock | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 6,800 | 6,800 (0%) | 0% | 0 | Common Stock | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 19,500 | 19,500 | - | - | Stock Option (Right to Buy) | |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 6,800 | 15,600 (0%) | 0% | 0 | Common Stock | |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 19,500 | 19,500 | - | - | Stock Option (Right to Buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 19,500 | 19,500 | - | - | Stock Option (Right to Buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 6,800 | 21,950 (0%) | 0% | 0 | Common Stock | |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.04 per share. | 07 Jun 2023 | 4,049 | 59,392 (0%) | 0% | 20.0 | 81,142 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 16.81 per share. | 16 Mar 2023 | 8,729 | 406,217 (0%) | 0% | 16.8 | 146,734 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 23.52 per share. | 26 Jan 2023 | 1,600 | 414,946 (0%) | 0% | 23.5 | 37,632 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 23.56 per share. | 26 Jan 2023 | 300 | 416,546 (0%) | 0% | 23.6 | 7,068 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 105,700 | 469,123 (1%) | 0% | 0 | Common Stock | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 429,000 | 429,000 | - | - | Stock Option (right to buy) | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 185,900 | 185,900 | - | - | Stock Option (right to buy) | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 45,800 | 324,682 (0%) | 0% | 0 | Common Stock | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 34,000 | 63,441 (0%) | 0% | 0 | Common Stock | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 138,200 | 138,200 | - | - | Stock Option (right to buy) | |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 185,900 | 185,900 | - | - | Stock Option (right to buy) | |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 45,800 | 416,846 (0%) | 0% | 0 | Common Stock | |
| Dimitry SA Nuyten | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 34,000 | 76,500 (0%) | 0% | 0 | Common Stock | |
| Dimitry SA Nuyten | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 138,200 | 138,200 | - | - | Stock Option (Right to Buy) | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 138,200 | 138,200 | - | - | Stock Option (right to buy) | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2023 | 34,000 | 97,539 (0%) | 0% | 0 | Common Stock | |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 30.66 per share. | 16 Dec 2022 | 10,983 | 244,233 (0%) | 0% | 30.7 | 336,739 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 31.23 per share. | 16 Dec 2022 | 2,060 | 242,173 (0%) | 0% | 31.2 | 64,334 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 31.23 per share. | 16 Dec 2022 | 701 | 218,258 (0%) | 0% | 31.2 | 21,892 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 30.66 per share. | 16 Dec 2022 | 3,735 | 218,959 (0%) | 0% | 30.7 | 114,515 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.66 per share. | 16 Dec 2022 | 2,066 | 11,953 (0%) | 0% | 30.7 | 63,344 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 31.23 per share. | 16 Dec 2022 | 387 | 11,566 (0%) | 0% | 31.2 | 12,086 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 30.66 per share. | 16 Dec 2022 | 13,879 | 150,212 (0%) | 0% | 30.7 | 425,530 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 31.23 per share. | 16 Dec 2022 | 2,603 | 147,609 (0%) | 0% | 31.2 | 81,292 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 31.23 per share. | 16 Dec 2022 | 398 | 28,584 (0%) | 0% | 31.2 | 12,430 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 30.66 per share. | 16 Dec 2022 | 2,125 | 28,982 (0%) | 0% | 30.7 | 65,153 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 26.28 per share. | 16 Sep 2022 | 12,677 | 130,942 (0%) | 0% | 26.3 | 333,152 | Common Stock |
| Dimitry SA Nuyten | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Aug 2022 | 170,000 | 170,000 | - | - | Stock Option (Right to Buy) | |
| Dimitry SA Nuyten | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Aug 2022 | 42,500 | 42,500 (0%) | 0% | 0 | Common Stock | |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 20.72 per share. | 16 Jun 2022 | 4,241 | 232,329 (0%) | 0% | 20.7 | 87,874 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 21.71 per share. | 16 Jun 2022 | 1,361 | 230,968 (0%) | 0% | 21.7 | 29,547 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 22.29 per share. | 16 Jun 2022 | 3,252 | 227,716 (0%) | 0% | 22.3 | 72,487 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 21.71 per share. | 16 Jun 2022 | 748 | 211,826 (0%) | 0% | 21.7 | 16,239 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 22.29 per share. | 16 Jun 2022 | 1,789 | 210,037 (0%) | 0% | 22.3 | 39,877 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 20.72 per share. | 16 Jun 2022 | 2,333 | 212,574 (0%) | 0% | 20.7 | 48,340 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 22.29 per share. | 16 Jun 2022 | 4,663 | 118,619 (0%) | 0% | 22.3 | 103,938 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 21.71 per share. | 16 Jun 2022 | 1,951 | 123,282 (0%) | 0% | 21.7 | 42,356 | Common Stock |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 20.72 per share. | 16 Jun 2022 | 6,081 | 125,233 (0%) | 0% | 20.7 | 125,998 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 20.72 per share. | 16 Jun 2022 | 1,400 | 25,431 (0%) | 0% | 20.7 | 29,008 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 21.71 per share. | 16 Jun 2022 | 449 | 24,982 (0%) | 0% | 21.7 | 9,748 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 22.29 per share. | 16 Jun 2022 | 1,073 | 23,909 (0%) | 0% | 22.3 | 23,917 | Common Stock |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 16,800 | 16,800 | - | - | Stock Option (Right to Buy) | |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 4,100 | 10,100 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 16,800 | 16,800 | - | - | Stock Option (Right to Buy) | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 4,100 | 90,604 (0%) | 0% | 0 | Common Stock | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 16,800 | 16,800 | - | - | Stock Option (Right to Buy) | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 4,100 | 11,125 (0%) | 0% | 0 | Common Stock | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 16,800 | 16,800 | - | - | Stock Option (Right to Buy) | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 4,100 | 42,452 (0%) | 0% | 0 | Common Stock | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 16,800 | 16,800 | - | - | Stock Option (Right to Buy) | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 4,100 | 4,100 (0%) | 0% | 0 | Common Stock | |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 16,800 | 16,800 | - | - | Stock Option (Right to Buy) | |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 4,100 | 4,100 (0%) | 0% | 0 | Common Stock | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 16,800 | 16,800 | - | - | Stock Option (Right to Buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 4,100 | 15,150 (0%) | 0% | 0 | Common Stock | |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 31.62 per share. | 16 Mar 2022 | 9,617 | 105,978 (0%) | 0% | 31.6 | 304,090 | Common Stock |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 125,000 | 125,000 | - | - | Stock Option (right to buy) | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 31,250 | 232,407 (0%) | 0% | 0 | Common Stock | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 15,500 | 22,519 (0%) | 0% | 0 | Common Stock | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 62,500 | 62,500 | - | - | Stock Option (right to buy) | |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 125,000 | 125,000 | - | - | Stock Option (right to buy) | |
| Jennifer Ann Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 31,250 | 121,845 (0%) | 0% | 0 | Common Stock | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 65,000 | 65,000 | - | - | Stock Option (right to buy) | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2022 | 16,250 | 33,814 (0%) | 0% | 0 | Common Stock | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2022 | 275,000 | 275,000 | - | - | Stock Option (right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2022 | 65,000 | 276,570 (0%) | 0% | 0 | Common Stock | |
| Terry Rosen | Director, Chief Executive Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 07 Mar 2022 | 321,074 | 0 (0%) | 0% | 0 | Common Stock | |
| Juan Carlos Jaen | Director, President | Gift of securities by or to the insider at price $ 0.00 per share. | 28 Feb 2022 | 350,000 | 1,222,240 (2%) | 0% | 0 | Common Stock | |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 40.88 per share. | 20 Dec 2021 | 11,099 | 114,318 (0%) | 0% | 40.9 | 453,677 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 42.23 per share. | 20 Dec 2021 | 2,800 | 90,595 (0%) | 0% | 42.2 | 118,234 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 41.70 per share. | 20 Dec 2021 | 20,923 | 93,395 (0%) | 0% | 41.7 | 872,458 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 38.79 per share. | 16 Dec 2021 | 653 | 213,860 (0%) | 0% | 38.8 | 25,328 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 40.46 per share. | 16 Dec 2021 | 619 | 214,513 (0%) | 0% | 40.5 | 25,043 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 39.59 per share. | 16 Dec 2021 | 1,680 | 215,132 (0%) | 0% | 39.6 | 66,514 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 40.57 per share. | 16 Dec 2021 | 808 | 212,635 (0%) | 0% | 40.6 | 32,783 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 39.67 per share. | 16 Dec 2021 | 417 | 213,443 (0%) | 0% | 39.7 | 16,543 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 41.42 per share. | 16 Dec 2021 | 1,065 | 211,570 (0%) | 0% | 41.4 | 44,116 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 40.57 per share. | 16 Dec 2021 | 304 | 201,558 (0%) | 0% | 40.6 | 12,334 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 39.67 per share. | 16 Dec 2021 | 157 | 201,862 (0%) | 0% | 39.7 | 6,228 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 38.79 per share. | 16 Dec 2021 | 246 | 202,019 (0%) | 0% | 38.8 | 9,542 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 40.45 per share. | 16 Dec 2021 | 233 | 202,265 (0%) | 0% | 40.5 | 9,426 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 39.59 per share. | 16 Dec 2021 | 632 | 202,498 (0%) | 0% | 39.6 | 25,022 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 41.42 per share. | 16 Dec 2021 | 401 | 201,157 (0%) | 0% | 41.4 | 16,611 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 39.59 per share. | 16 Dec 2021 | 354 | 7,771 (0%) | 0% | 39.6 | 14,015 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 41.42 per share. | 16 Dec 2021 | 224 | 7,019 (0%) | 0% | 41.4 | 9,279 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 40.57 per share. | 16 Dec 2021 | 171 | 7,243 (0%) | 0% | 40.6 | 6,938 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 39.67 per share. | 16 Dec 2021 | 88 | 7,414 (0%) | 0% | 39.7 | 3,491 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 38.79 per share. | 16 Dec 2021 | 138 | 7,502 (0%) | 0% | 38.8 | 5,353 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 40.46 per share. | 16 Dec 2021 | 131 | 7,640 (0%) | 0% | 40.5 | 5,300 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 41.42 per share. | 16 Dec 2021 | 2,575 | 125,417 (0%) | 0% | 41.4 | 106,666 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 40.57 per share. | 16 Dec 2021 | 1,955 | 127,992 (0%) | 0% | 40.6 | 79,321 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 39.67 per share. | 16 Dec 2021 | 1,008 | 129,947 (0%) | 0% | 39.7 | 39,989 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 38.79 per share. | 16 Dec 2021 | 1,580 | 130,955 (0%) | 0% | 38.8 | 61,285 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 40.46 per share. | 16 Dec 2021 | 1,496 | 132,535 (0%) | 0% | 40.5 | 60,523 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 39.59 per share. | 16 Dec 2021 | 4,064 | 134,031 (0%) | 0% | 39.6 | 160,900 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 38.79 per share. | 16 Dec 2021 | 138 | 18,048 (0%) | 0% | 38.8 | 5,353 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 41.42 per share. | 16 Dec 2021 | 225 | 17,564 (0%) | 0% | 41.4 | 9,320 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 40.57 per share. | 16 Dec 2021 | 171 | 17,789 (0%) | 0% | 40.6 | 6,938 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 39.67 per share. | 16 Dec 2021 | 88 | 17,960 (0%) | 0% | 39.7 | 3,491 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 40.46 per share. | 16 Dec 2021 | 131 | 18,186 (0%) | 0% | 40.5 | 5,300 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 39.59 per share. | 16 Dec 2021 | 356 | 18,317 (0%) | 0% | 39.6 | 14,095 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 35.98 per share. | 20 Sep 2021 | 4,885 | 112,843 (0%) | 0% | 36.0 | 175,762 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 35.50 per share. | 20 Sep 2021 | 11,981 | 117,728 (0%) | 0% | 35.5 | 425,326 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 35.67 per share. | 20 Sep 2021 | 600 | 129,709 (0%) | 0% | 35.7 | 21,402 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 35.06 per share. | 20 Sep 2021 | 21,900 | 130,309 (0%) | 0% | 35.1 | 767,814 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 35.48 per share. | 20 Sep 2021 | 8,134 | 152,209 (0%) | 0% | 35.5 | 288,610 | Common Stock |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 4,700 | 4,700 (0%) | 0% | 0 | Common Stock | |
| Nicole Lambert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 21,700 | 21,700 | - | - | Stock Option (Right to Buy) | |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 24.77 per share. | 16 Jun 2021 | 159 | 210,425 (0%) | 0% | 24.8 | 3,938 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 23.68 per share. | 16 Jun 2021 | 4,863 | 205,562 (0%) | 0% | 23.7 | 115,156 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 24.13 per share. | 16 Jun 2021 | 3,809 | 210,584 (0%) | 0% | 24.1 | 91,911 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 24.13 per share. | 16 Jun 2021 | 2,095 | 201,048 (0%) | 0% | 24.1 | 50,552 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 24.77 per share. | 16 Jun 2021 | 87 | 200,961 (0%) | 0% | 24.8 | 2,155 | Common Stock |
| Juan Carlos Jaen | Director, President | Sale of securities on an exchange or to another person at price $ 23.68 per share. | 16 Jun 2021 | 2,675 | 198,286 (0%) | 0% | 23.7 | 63,344 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 23.68 per share. | 16 Jun 2021 | 4,863 | 135,343 (0%) | 0% | 23.7 | 115,156 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 24.13 per share. | 16 Jun 2021 | 3,809 | 140,365 (0%) | 0% | 24.1 | 91,911 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 24.77 per share. | 16 Jun 2021 | 159 | 140,206 (0%) | 0% | 24.8 | 3,938 | Common Stock |
| William Grossman | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 24.77 per share. | 16 Jun 2021 | 127 | 24,614 (0%) | 0% | 24.8 | 3,146 | Common Stock |
| William Grossman | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 24.13 per share. | 16 Jun 2021 | 3,047 | 24,741 (0%) | 0% | 24.1 | 73,524 | Common Stock |
| William Grossman | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 23.68 per share. | 16 Jun 2021 | 3,891 | 20,723 (0%) | 0% | 23.7 | 92,139 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 24.13 per share. | 16 Jun 2021 | 1,257 | 17,020 (0%) | 0% | 24.1 | 30,331 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 24.77 per share. | 16 Jun 2021 | 52 | 16,968 (0%) | 0% | 24.8 | 1,288 | Common Stock |
| Carolyn C. Tang | General Counsel | Sale of securities on an exchange or to another person at price $ 23.68 per share. | 16 Jun 2021 | 1,606 | 15,362 (0%) | 0% | 23.7 | 38,030 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 24.91 per share. | 04 Jun 2021 | 1,044 | 119,174 (0%) | 0% | 24.9 | 26,006 | Common Stock |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 14,100 | 14,100 | - | - | Stock Option (Right to Buy) | |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 3,000 | 6,000 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 3,000 | 86,504 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 14,100 | 14,100 | - | - | Stock Option (Right to Buy) | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 14,100 | 14,100 | - | - | Stock Option (Right to Buy) | |
| Andrew J. Perlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 3,000 | 5,525 (0%) | 0% | 0 | Common Stock | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 3,000 | 38,352 (0%) | 0% | 0 | Common Stock | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 14,100 | 14,100 | - | - | Stock Option (Right to Buy) | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 14,100 | 14,100 | - | - | Stock Option (Right to Buy) | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 3,000 | 6,000 (0%) | 0% | 0 | Common Stock | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 14,100 | 14,100 | - | - | Stock Option (Right to Buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2021 | 3,000 | 11,050 (0%) | 0% | 0 | Common Stock | |
| William Grossman | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 31.37 per share. | 23 Apr 2021 | 4,133 | 6,717 (0%) | 0% | 31.4 | 129,652 | Common Stock |
| Yasunori Kaneko | Director | Purchase of securities on an exchange or from another person at price $ 31.37 per share. | 23 Apr 2021 | 4,133 | 7,133 (0%) | 0% | 31.4 | 129,652 | Common Stock |
| Kathryn E. Falberg | Director | Purchase of securities on an exchange or from another person at price $ 28.35 per share. | 31 Mar 2021 | 20,000 | 102,106 (0%) | 0% | 28.3 | 566,996 | Common Stock |
| Jennifer Jarrett | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 35.03 per share. | 16 Mar 2021 | 8,661 | 116,973 (0%) | 0% | 35.0 | 303,394 | Common Stock |
| William Grossman | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 35.03 per share. | 16 Mar 2021 | 2,127 | 10,850 (0%) | 0% | 35.0 | 74,509 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Feb 2021 | 311,900 | 0 (0%) | 0% | 0 | Common Stock | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 280,000 | 280,000 | - | - | Stock Option (right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 45,000 | 234,393 (0%) | 0% | 0 | Common Stock | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 19,375 | 208,768 (0%) | 0% | 0 | Common Stock | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 116,250 | 116,250 | - | - | Stock Option (right to buy) | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 12,500 | 17,500 (0%) | 0% | 0 | Common Stock | |
| Jennifer Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 400,000 | 500,634 (1%) | 0% | 0 | Common Stock | |
| William Grossman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 18,750 | 25,477 (0%) | 0% | 0 | Common Stock | |
| William Grossman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 112,500 | 112,500 | - | - | Stock Option (right to buy) | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 12,538 | 19,886 (0%) | 0% | 0 | Common Stock | |
| Carolyn C. Tang | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 75,225 | 75,225 | - | - | Stock Option (right to buy) | |
| William Grossman | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 31.35 per share. | 16 Dec 2020 | 2,117 | 6,727 (0%) | 0% | 31.4 | 66,368 | Common Stock |
| Juan Carlos Jaen | Director, President | Gift of securities by or to the insider at price $ 0.00 per share. | 13 Oct 2020 | 1,207,000 | 1,572,240 (3%) | 2% | 0 | Common Stock | |
| William Grossman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2020 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| William Grossman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2020 | 100,000 | 100,600 (0%) | 0% | 0 | Common Stock | |
| Jennifer Jarrett | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 900,000 | 900,000 | - | - | Stock Option (Right to Buy) | |
| Robert C. Goeltz | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 21.57 per share. | 09 Sep 2020 | 5,000 | 5,000 (0%) | 0% | 21.6 | 107,849 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 23.38 per share. | 07 Aug 2020 | 32,050 | 3,231,179 (7%) | 0% | 23.4 | 749,403 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 21.44 per share. | 07 Aug 2020 | 11,655 | 3,199,129 (6%) | 0% | 21.4 | 249,911 | Common Stock |
| Robert C. Goeltz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2020 | 250,000 | 250,000 | - | - | Stock Option (right to buy) | |
| William Grossman | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 19.77 per share. | 31 Jul 2020 | 100 | 500 (0%) | 0% | 19.8 | 1,977 | Common Stock |
| William Grossman | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 19.68 per share. | 31 Jul 2020 | 100 | 600 (0%) | 0% | 19.7 | 1,968 | Common Stock |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 3,000 | 3,000 (0%) | 0% | 0 | Common Stock | |
| Patrick C. Machado | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 14,000 | 14,000 | - | - | Stock Option (Right to Buy) | |
| Jason Barker | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 10,000 | 10,000 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 3,000 | 83,504 (0%) | 0% | 0 | Common Stock | |
| Kathryn E. Falberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 14,000 | 14,000 | - | - | Stock Option (Right to Buy) | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 100,000 | 289,393 (0%) | 0% | 0 | Common Stock | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 55,000 | 244,393 (0%) | 0% | 0 | Common Stock | |
| Jennifer Jarrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 14,000 | 14,000 | - | - | Stock Option (Right to Buy) | |
| Jennifer Jarrett | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 3,000 | 103,634 (0%) | 0% | 0 | Common Stock | |
| William Grossman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 55,000 | 55,400 (0%) | 0% | 0 | Common Stock | |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 14,000 | 14,000 | - | - | Stock Option (Right to Buy) | |
| Yasunori Kaneko | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.99 per share. | 04 Jun 2020 | 35,000 | 38,000 (0%) | 0% | 8.0 | 279,650 | Common Stock |
| Yasunori Kaneko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 3,000 | 3,000 (0%) | 0% | 0 | Common Stock | |
| Yasunori Kaneko | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2020 | 35,000 | 0 | - | - | Stock Option (Rights to Buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 3,000 | 8,050 (0%) | 0% | 0 | Common Stock | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2020 | 14,000 | 14,000 | - | - | Stock Option (Right to Buy) | |
| David L. Lacey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2020 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Jason Barker | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2020 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2020 | 350,000 | 350,000 | - | - | Stock Option (right to buy) | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2020 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| William Grossman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2020 | 140,000 | 140,000 | - | - | Stock Option (right to buy) | |
| Antoni Ribas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2020 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Patrick C. Machado | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2019 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Antoni Ribas | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Oct 2019 | 50,000 | 50,000 | - | - | Stock Option (Right to buy) | |
| William Grossman | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 10 Oct 2019 | 100 | 100 (0%) | 0% | 8 | 800 | Common Stock |
| William Grossman | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 10 Oct 2019 | 300 | 400 (0%) | 0% | 8 | 2,400 | Common Stock |
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 7.89 per share. | 27 Jun 2019 | 4,894 | 2,779,240 (6%) | 0% | 7.9 | 38,637 | Common Stock |
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 7.44 per share. | 27 Jun 2019 | 10,106 | 2,774,346 (6%) | 0% | 7.4 | 75,217 | Common Stock |
| Kathryn E. Falberg | None | Purchase of securities on an exchange or from another person at price $ 8.52 per share. | 13 Jun 2019 | 12,935 | 82,106 (0%) | 0% | 8.5 | 110,152 | Common Stock |
| Kathryn E. Falberg | None | Purchase of securities on an exchange or from another person at price $ 8.49 per share. | 11 Jun 2019 | 10,000 | 69,171 (0%) | 0% | 8.5 | 84,928 | Common Stock |
| Kathryn E. Falberg | None | Purchase of securities on an exchange or from another person at price $ 7.90 per share. | 11 Jun 2019 | 10,000 | 59,171 (0%) | 0% | 7.9 | 79,000 | Common Stock |
| Kathryn E. Falberg | None | Purchase of securities on an exchange or from another person at price $ 8.25 per share. | 07 Jun 2019 | 10,000 | 49,171 (0%) | 0% | 8.3 | 82,500 | Common Stock |
| Kathryn E. Falberg | None | Purchase of securities on an exchange or from another person at price $ 7.99 per share. | 07 Jun 2019 | 22,065 | 39,171 (0%) | 0% | 8.0 | 176,297 | Common Stock |
| Kathryn E. Falberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2019 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Kristen M. Hege | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2019 | 35,000 | 35,000 | - | - | Stock Option (Right to buy) | |
| David William Beier | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2019 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Jennifer Jarrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2019 | 35,000 | 35,000 | - | - | Stock Option (Right to buy) | |
| Yasunori Kaneko | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2019 | 35,000 | 35,000 | - | - | Stock Option (Right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 7.93 per share. | 05 Jun 2019 | 19,358 | 3,020,759 (6%) | 0% | 7.9 | 153,416 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 7.95 per share. | 05 Jun 2019 | 2,380 | 3,023,139 (6%) | 0% | 8.0 | 18,928 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 7.75 per share. | 03 Jun 2019 | 25,770 | 3,001,401 (6%) | 0% | 7.8 | 199,826 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 8.16 per share. | 03 Jun 2019 | 15,770 | 2,975,631 (6%) | 0% | 8.2 | 128,749 | Common Stock |
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 8.25 per share. | 03 Jun 2019 | 10,000 | 2,764,240 (6%) | 0% | 8.2 | 82,485 | Common Stock |
| William Grossman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Apr 2019 | 400,000 | 400,000 | - | - | Stock Option (right to buy) | |
| Rekha Hemrajani | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Mar 2019 | 400,000 | 400,000 | - | - | Stock Option (right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2019 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| Juan Carlos Jaen | Director, President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2019 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| Steven Chan | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2019 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Jennifer Jarrett | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2019 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 11.80 per share. | 13 Nov 2018 | 10,000 | 2,754,240 (6%) | 0% | 11.8 | 118,039 | Common Stock |
| Kristen M. Hege | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Oct 2018 | 35,000 | 35,000 | - | - | Stock Option (right to buy) | |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 15.48 per share. | 27 Aug 2018 | 10,650 | 3,959,861 (8%) | 0% | 15.5 | 164,845 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 14.92 per share. | 27 Aug 2018 | 800 | 3,949,211 (8%) | 0% | 14.9 | 11,937 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 14.48 per share. | 27 Aug 2018 | 7,157 | 3,948,411 (8%) | 0% | 14.5 | 103,649 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 13.40 per share. | 22 Aug 2018 | 4,954 | 3,941,254 (8%) | 0% | 13.4 | 66,363 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 13.50 per share. | 22 Aug 2018 | 2,133 | 3,936,300 (8%) | 0% | 13.5 | 28,800 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 13.52 per share. | 22 Aug 2018 | 2,202 | 3,934,167 (8%) | 0% | 13.5 | 29,777 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 13.20 per share. | 17 Aug 2018 | 2,790 | 3,931,965 (8%) | 0% | 13.2 | 36,828 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 13.21 per share. | 17 Aug 2018 | 1,301 | 3,929,175 (8%) | 0% | 13.2 | 17,186 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 13.27 per share. | 17 Aug 2018 | 4,800 | 3,927,874 (8%) | 0% | 13.3 | 63,713 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 12.95 per share. | 14 Aug 2018 | 8,932 | 3,923,074 (8%) | 0% | 12.9 | 115,649 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 12.57 per share. | 14 Aug 2018 | 13,300 | 3,914,142 (8%) | 0% | 12.6 | 167,240 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 12.36 per share. | 14 Aug 2018 | 6,169 | 3,900,842 (8%) | 0% | 12.4 | 76,239 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 11.75 per share. | 09 Aug 2018 | 3,279 | 3,894,673 (8%) | 0% | 11.8 | 38,534 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 11.92 per share. | 09 Aug 2018 | 4,100 | 3,888,844 (8%) | 0% | 11.9 | 48,869 | Common Stock |
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 11.94 per share. | 09 Aug 2018 | 2,550 | 3,891,394 (8%) | 0% | 11.9 | 30,451 | Common Stock |
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 11.93 per share. | 09 Aug 2018 | 4,262 | 2,738,502 (6%) | 0% | 11.9 | 50,855 | Common Stock |
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 11.94 per share. | 09 Aug 2018 | 2,579 | 2,741,081 (6%) | 0% | 11.9 | 30,796 | Common Stock |
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 11.77 per share. | 09 Aug 2018 | 3,159 | 2,744,240 (6%) | 0% | 11.8 | 37,168 | Common Stock |
| Jennifer Jarrett | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2018 | 161,114 | 161,114 | - | - | Stock Option (right to buy) | |
| Kathryn E. Falberg | None | Purchase of securities on an exchange or from another person at price $ 15.00 per share. | 19 Mar 2018 | 30,000 | 80,504 (0%) | 0% | 15 | 450,000 | Common Stock |
| Kathryn E. Falberg | None | 19 Mar 2018 | 17,106 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Kathryn E. Falberg | None | 19 Mar 2018 | 17,106 | 17,106 (0%) | 0% | 0 | Common Stock | ||
| Terry Rosen | Director, Chief Executive Officer | 19 Mar 2018 | 2,267,676 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Terry Rosen | Director, Chief Executive Officer | 19 Mar 2018 | 125,012 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Terry Rosen | Director, Chief Executive Officer | 19 Mar 2018 | 82,966 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Terry Rosen | Director, Chief Executive Officer | 19 Mar 2018 | 2,475,654 | 3,818,078 (8%) | 5% | 0 | Common Stock | ||
| Terry Rosen | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 15.00 per share. | 19 Mar 2018 | 66,666 | 3,884,744 (9%) | 0% | 15 | 999,990 | Common Stock |
| Juan Carlos Jaen | Director, President | 19 Mar 2018 | 2,020,202 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Juan Carlos Jaen | Director, President | 19 Mar 2018 | 125,012 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Juan Carlos Jaen | Director, President | 19 Mar 2018 | 29,936 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Juan Carlos Jaen | Director, President | 19 Mar 2018 | 2,175,150 | 2,667,574 (6%) | 5% | 0 | Common Stock | ||
| Juan Carlos Jaen | Director, President | Purchase of securities on an exchange or from another person at price $ 15.00 per share. | 19 Mar 2018 | 66,666 | 2,734,240 (6%) | 0% | 15 | 999,990 | Common Stock |
| Yasunori Kaneko | None | 19 Mar 2018 | 252,524 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Yasunori Kaneko | None | 19 Mar 2018 | 505,050 | 505,050 (1%) | 1% | 0 | Common Stock | ||
| Yasunori Kaneko | None | 19 Mar 2018 | 252,524 | 252,524 (0%) | 0% | 0 | Common Stock | ||
| Yasunori Kaneko | None | 19 Mar 2018 | 33,818 | 96,948 (0%) | 0% | 0 | Common Stock | ||
| Yasunori Kaneko | None | 19 Mar 2018 | 2,565 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Yasunori Kaneko | None | 19 Mar 2018 | 31,253 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Yasunori Kaneko | None | 19 Mar 2018 | 505,050 | 0 | - | - | Series A Convertible Preferred Stock |