582.8K XNAS Volume
XNAS 19 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Marcio Souza | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 85.40 per share. | 12 Feb 2025 | 401 | 53,559 | - | 85.4 | 34,245 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 85.39 per share. | 12 Feb 2025 | 51 | 20,831 | - | 85.4 | 4,355 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 85.40 per share. | 12 Feb 2025 | 40 | 10,441 | - | 85.4 | 3,416 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 37,500 | 53,960 | - | 0 | Common Stock | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 11,250 | 21,461 | - | 0 | Common Stock | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 22,500 | 22,500 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 63.15 per share. | 10 Jan 2025 | 579 | 20,882 | - | 63.2 | 36,564 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 63.15 per share. | 10 Jan 2025 | 390 | 10,481 | - | 63.2 | 24,629 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 5,000 | 10,871 | - | 0 | Common Stock | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 12,500 | 24,706 | - | 0 | Common Stock | |
| Timothy E. Kelly | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 63.15 per share. | 10 Jan 2025 | 676 | 24,030 | - | 63.1 | 42,689 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 77.52 per share. | 07 Jan 2025 | 434 | 16,460 | - | 77.5 | 33,644 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 77.52 per share. | 07 Jan 2025 | 89 | 10,211 | - | 77.5 | 6,899 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 77.51 per share. | 07 Jan 2025 | 35 | 5,871 | - | 77.5 | 2,713 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 77.52 per share. | 07 Jan 2025 | 139 | 12,206 | - | 77.5 | 10,775 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Nov 2024 | 7,583 | 28,817 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Sale of securities on an exchange or to another person at price $ 80.21 per share. | 14 Nov 2024 | 8,239 | 10,300 | - | 80.2 | 660,827 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 56.94 per share. | 14 Nov 2024 | 7,583 | 18,540 | - | 56.9 | 431,776 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 56.94 per share. | 14 Nov 2024 | 4,374 | 10,801 | - | 56.9 | 249,056 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Nov 2024 | 4,374 | 16,626 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Sale of securities on an exchange or to another person at price $ 81.79 per share. | 14 Nov 2024 | 5,188 | 5,612 | - | 81.8 | 424,318 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 37.40 per share. | 14 Nov 2024 | 294 | 5,906 | - | 37.4 | 10,996 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 37.40 per share. | 14 Nov 2024 | 205 | 12,345 | - | 37.4 | 7,667 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 185,000 | 185,000 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 7,800 | 10,957 | - | 0 | Common Stock | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 36,400 | 36,400 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 4,500 | 6,427 | - | 0 | Common Stock | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 21,000 | 21,000 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 36,400 | 36,400 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 7,800 | 12,140 | - | 0 | Common Stock | |
| Dean Jonathan Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 8,566 | 8,566 | - | - | Stock Option (Right to Buy) | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 8,566 | 8,566 | - | - | Stock Option (Right to Buy) | |
| William D. Young | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 8,566 | 8,566 | - | - | Stock Option (Right to Buy) | |
| Jeffrey A. Chodakewitz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 8,566 | 8,566 | - | - | Stock Option (Right to Buy) | |
| Merit Ester Cudkowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 8,566 | 8,566 | - | - | Stock Option (Right to Buy) | |
| Jill DeSimone | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 8,566 | 8,566 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 12.37 per share. | 14 May 2024 | 1,718 | 16,894 | - | 12.4 | 21,248 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 12.37 per share. | 14 May 2024 | 606 | 4,340 | - | 12.4 | 7,495 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 44.65 per share. | 12 Feb 2024 | 51 | 3,157 | - | 44.6 | 2,277 | Common Stock |
| Souza Marcio | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 44.65 per share. | 12 Feb 2024 | 271 | 15,176 | - | 44.6 | 12,100 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 44.65 per share. | 12 Feb 2024 | 48 | 1,927 | - | 44.6 | 2,143 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2024 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Nemiroff Alex | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2024 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2024 | 12,000 | 12,000 | - | - | Stock Option (Right to Buy) | |
| Kelly Timothy E. | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2024 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.19 per share. | 07 Jan 2024 | 418 | 15,447 | - | 25.2 | 10,529 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.20 per share. | 07 Jan 2024 | 35 | 1,975 | - | 25.2 | 882 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.19 per share. | 07 Jan 2024 | 89 | 3,208 | - | 25.2 | 2,242 | Common Stock |
| Timothy Kelly E. | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.19 per share. | 07 Jan 2024 | 139 | 3,734 | - | 25.2 | 3,501 | Common Stock |
| Dean Jonathan Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2023 | 28,981 | 28,981 | - | - | Stock Option (Right to Buy) | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2023 | 28,981 | 28,981 | - | - | Stock Option (Right to Buy) | |
| William D. Young | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2023 | 28,981 | 28,981 | - | - | Stock Option (Right to Buy) | |
| Jeffrey A. Chodakewitz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2023 | 28,981 | 28,981 | - | - | Stock Option (Right to Buy) | |
| Merit Ester Cudkowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2023 | 28,981 | 28,981 | - | - | Stock Option (Right to Buy) | |
| Jill DeSimone | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2023 | 28,981 | 28,981 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.88 per share. | 12 May 2023 | 11,687 | 237,986 | - | 0.9 | 10,331 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.88 per share. | 12 May 2023 | 11,686 | 49,460 | - | 0.9 | 10,330 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.88 per share. | 12 May 2023 | 11,683 | 58,099 | - | 0.9 | 10,328 | Common Stock |
| Dean Jonathan Mitchell | Director | Purchase of securities on an exchange or from another person at price $ 0.84 per share. | 24 Mar 2023 | 50,000 | 75,000 | - | 0.8 | 41,815 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.87 per share. | 24 Mar 2023 | 8,000 | 46,416 | - | 0.9 | 6,998 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.86 per share. | 23 Mar 2023 | 35,001 | 35,001 | - | 0.9 | 30,207 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.86 per share. | 23 Mar 2023 | 35,000 | 226,299 | - | 0.9 | 30,160 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.94 per share. | 12 Feb 2023 | 920 | 37,774 | - | 3.9 | 3,625 | Common Stock |
| Nicole Sweeny | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.94 per share. | 12 Feb 2023 | 1,456 | 38,619 | - | 3.9 | 5,737 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.94 per share. | 12 Feb 2023 | 711 | 30,160 | - | 3.9 | 2,801 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 213,975 | 213,975 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 425,000 | 425,000 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 120,000 | 120,000 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 36,520 | 36,520 | - | - | Stock Option (Right to Buy) | |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 120,000 | 120,000 | - | - | Stock Option (Right to Buy) | |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 41,085 | 41,085 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 3,110 | 3,110 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jan 2023 | 42,455 | 42,455 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.52 per share. | 07 Jan 2023 | 1,335 | 38,694 | - | 2.5 | 3,364 | Common Stock |
| Nicole Sweeny | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.52 per share. | 07 Jan 2023 | 2,079 | 40,075 | - | 2.5 | 5,239 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.52 per share. | 07 Jan 2023 | 520 | 30,871 | - | 2.5 | 1,310 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.52 per share. | 07 Jan 2023 | 2,079 | 38,416 | - | 2.5 | 5,239 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 14 Nov 2022 | 2,115 | 191,299 | - | 1.8 | 3,830 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 1.81 per share. | 14 Nov 2022 | 682 | 40,029 | - | 1.8 | 1,235 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 1.80 per share. | 14 Nov 2022 | 5 | 40,495 | - | 1.8 | 9 | Common Stock |
| Bernard Ravina | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 65,000 | 65,000 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 65,000 | 65,000 | - | - | Stock Option (Right to Buy) | |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 65,000 | 65,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 65,000 | 65,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Purchase of securities on an exchange or from another person at price $ 1.92 per share. | 16 Jun 2022 | 3,000 | 31,391 | - | 1.9 | 5,775 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Purchase of securities on an exchange or from another person at price $ 1.63 per share. | 13 Jun 2022 | 7,500 | 39,347 | - | 1.6 | 12,225 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.76 per share. | 09 Jun 2022 | 10,000 | 40,490 | - | 1.8 | 17,650 | Common Stock |
| Dean Jonathan Mitchell | Director | Purchase of securities on an exchange or from another person at price $ 1.81 per share. | 08 Jun 2022 | 25,000 | 25,000 | - | 1.8 | 45,188 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 1.85 per share. | 08 Jun 2022 | 27,000 | 189,184 | - | 1.8 | 49,888 | Common Stock |
| Dean Jonathan Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 22,753 | 22,753 | - | - | Stock Option (Right to Buy) | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 22,753 | 22,753 | - | - | Stock Option (Right to Buy) | |
| William D. Young | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 22,753 | 22,753 | - | - | Stock Option (Right to Buy) | |
| Jeffrey A. Chodakewitz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 22,753 | 22,753 | - | - | Stock Option (Right to Buy) | |
| Stefan Vitorovic | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 22,753 | 22,753 | - | - | Stock Option (Right to Buy) | |
| Merit Ester Cudkowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 22,753 | 22,753 | - | - | Stock Option (Right to Buy) | |
| Jill DeSimone | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2022 | 45,511 | 45,511 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 8.80 per share. | 13 May 2022 | 1,392 | 162,184 | - | 8.8 | 12,247 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 8.80 per share. | 13 May 2022 | 2,202 | 31,847 | - | 8.8 | 19,373 | Common Stock |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 8.80 per share. | 13 May 2022 | 2,587 | 42,154 | - | 8.8 | 22,760 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 8.80 per share. | 13 May 2022 | 2,557 | 28,391 | - | 8.8 | 22,496 | Common Stock |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 8.80 per share. | 13 May 2022 | 2,585 | 30,490 | - | 8.8 | 22,743 | Common Stock |
| Bernard Ravina | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.85 per share. | 12 Feb 2022 | 3,057 | 99,476 | - | 12.8 | 39,282 | Common Stock |
| Alex Nemiroff | General Counsel and Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.85 per share. | 12 Feb 2022 | 755 | 29,645 | - | 12.9 | 9,702 | Common Stock |
| Nicole Sweeny | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.85 per share. | 12 Feb 2022 | 1,233 | 39,567 | - | 12.8 | 15,844 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.85 per share. | 12 Feb 2022 | 584 | 25,834 | - | 12.8 | 7,504 | Common Stock |
| Bernard Ravina | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 22,000 | 102,533 | - | 0 | Common Stock | |
| Bernard Ravina | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 77,000 | 77,000 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 259,000 | 259,000 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 74,000 | 160,792 | - | 0 | Common Stock | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 18,000 | 30,400 | - | 0 | Common Stock | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 63,000 | 63,000 | - | - | Stock Option (Right to Buy) | |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 24,000 | 40,800 | - | 0 | Common Stock | |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 84,000 | 84,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 21,000 | 21,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 6,000 | 26,418 | - | 0 | Common Stock | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 84,000 | 84,000 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2022 | 24,000 | 27,905 | - | 0 | Common Stock | |
| Timothy E. Kelly | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 19.48 per share. | 31 Aug 2021 | 3,905 | 3,905 | - | 19.5 | 76,069 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 15.79 per share. | 18 Aug 2021 | 9,542 | 86,792 | - | 15.8 | 150,668 | Common Stock |
| Dean Jonathan Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2021 | 22,343 | 22,343 | - | - | Stock Option (Right to Buy) | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2021 | 22,343 | 22,343 | - | - | Stock Option (Right to Buy) | |
| William D. Young | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2021 | 22,343 | 22,343 | - | - | Stock Option (Right to Buy) | |
| Stefan Vitorovic | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2021 | 22,343 | 22,343 | - | - | Stock Option (Right to Buy) | |
| Timothy E. Kelly | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| William D. Young | Director | Other type of transaction at price $ 0.00 per share. | 13 May 2021 | 28,473 | 28,473 | - | 0 | Common Stock | |
| Gregory Norden | Director | Other type of transaction at price $ 0.00 per share. | 12 May 2021 | 2,826 | 2,826 | - | 0 | Common Stock | |
| Merit Ester Cudkowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2021 | 38,579 | 38,579 | - | - | Stock Option (Right to Buy) | |
| Jeffrey A. Chodakewitz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Apr 2021 | 38,579 | 38,579 | - | - | Stock Option (Right to Buy) | |
| Bernard Ravina | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 65,800 | 65,800 | - | - | Stock Option (Right to Buy) | |
| Bernard Ravina | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 24,512 | 80,533 | - | 0 | Common Stock | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 184,800 | 184,800 | - | - | Stock Option (Right to Buy) | |
| Marcio Souza | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 52,800 | 77,250 | - | 0 | Common Stock | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 43,400 | 43,400 | - | - | Stock Option (Right to Buy) | |
| Alex Nemiroff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 12,400 | 12,400 | - | 0 | Common Stock | |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 16,800 | 16,800 | - | 0 | Common Stock | |
| Nicole Sweeny | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 58,880 | 58,880 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 48,700 | 48,700 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 8,200 | 20,418 | - | 0 | Common Stock | |
| Bernard Ravina | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2021 | 45,000 | 139,479 | - | - | Stock Option (Right to Buy) | |
| Bernard Ravina | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.27 per share. | 04 Jan 2021 | 45,000 | 56,021 | - | 2.3 | 102,150 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 26.08 per share. | 10 Nov 2020 | 3,846 | 24,450 | - | 26.1 | 100,304 | Common Stock |
| Lauren Mastrocola | Principal Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Nov 2020 | 12,218 | 15,710 | - | - | Stock Option (Right to Buy) | |
| Lauren Mastrocola | Principal Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.30 per share. | 02 Nov 2020 | 12,218 | 12,218 | - | 3.3 | 40,319 | Common Stock |
| Marcio Souza | Director, Chief Executive Officer | 20 Oct 2020 | 20,604 | 20,604 | - | - | Common Stock | ||
| Marcio Souza | Director, Chief Executive Officer | 20 Oct 2020 | 44,092 | 0 | - | - | Series C -1 Preferred Stock | ||
| Stefan Vitorovic | Director | 20 Oct 2020 | 4,150,000 | 0 | - | - | Series B Preferred Stock | ||
| Stefan Vitorovic | Director | 20 Oct 2020 | 881,835 | 0 | - | - | Series C -1 Preferred Stock | ||
| Stefan Vitorovic | Director | 20 Oct 2020 | 171,410 | 0 | - | - | Series C Preferred Stock | ||
| Stefan Vitorovic | Director | 20 Oct 2020 | 551,794 | 0 | - | - | Series B -1 Preferred Stock | ||
| Stefan Vitorovic | Director | 20 Oct 2020 | 2,689,329 | 2,689,329 | - | - | Common Stock |