542.5K XNAS Volume
XNAS 18 Mar, 2025 4:01 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2025 | 30,600 | 68,516 (0%) | 0% | 0 | Common Stock | |
| Kristen Marie Williams | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2025 | 79,200 | 182,112 (0%) | 0% | 0 | Common Stock | |
| Frank D. Lee | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2025 | 350,000 | 448,409 (1%) | 0% | 0 | Common Stock | |
| Jonathan Slonin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2025 | 93,600 | 187,043 (0%) | 0% | 0 | Common Stock | |
| Brendan P. Teehan | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2025 | 54,000 | 54,000 (0%) | 0% | 0 | Common Stock | |
| Brendan P. Teehan | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2025 | 99,500 | 99,500 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Senior Vice President, Finance | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.33 per share. | 02 Jan 2025 | 159 | 37,916 (0%) | 0% | 18.3 | 2,914 | Common Stock |
| Frank D. Lee | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.33 per share. | 02 Jan 2025 | 9,375 | 98,409 (0%) | 0% | 18.3 | 171,844 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.33 per share. | 02 Jan 2025 | 371 | 94,322 (0%) | 0% | 18.3 | 6,800 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 18.40 per share. | 02 Jan 2025 | 879 | 93,443 (0%) | 0% | 18.4 | 16,174 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 16.05 per share. | 31 Dec 2024 | 243 | 115,443 (0%) | 0% | 16.0 | 3,900 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 19.76 per share. | 13 Dec 2024 | 500 | 115,199 (0%) | 0% | 19.8 | 9,880 | Common Stock |
| Shawn M. Cross | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Nov 2024 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Shawn M. Cross | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Nov 2024 | 75,000 | 75,000 (0%) | 0% | 0 | Common Stock | |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 12.86 per share. | 13 Sep 2024 | 500 | 115,699 (0%) | 0% | 12.9 | 6,430 | Common Stock |
| Laura A. Brege | Director | Purchase of securities on an exchange or from another person at price $ 12.81 per share. | 16 Aug 2024 | 1,000 | 17,552 (0%) | 0% | 12.8 | 12,810 | Common Stock |
| Marcelo Bigal | Director | Purchase of securities on an exchange or from another person at price $ 13.25 per share. | 16 Aug 2024 | 1,512 | 10,142 (0%) | 0% | 13.3 | 20,034 | Common Stock |
| Michael J. Yang | Director | Purchase of securities on an exchange or from another person at price $ 12.90 per share. | 14 Aug 2024 | 2,000 | 7,230 (0%) | 0% | 12.9 | 25,800 | Common Stock |
| Mark I. Froimson | Director | Purchase of securities on an exchange or from another person at price $ 11.58 per share. | 12 Aug 2024 | 1,400 | 14,473 (0%) | 0% | 11.6 | 16,212 | Common Stock |
| Marcelo Bigal | Director | Purchase of securities on an exchange or from another person at price $ 12.01 per share. | 12 Aug 2024 | 3,400 | 8,630 (0%) | 0% | 12.0 | 40,834 | Common Stock |
| Frank D. Lee | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 12.10 per share. | 12 Aug 2024 | 8,264 | 107,784 (0%) | 0% | 12.1 | 99,994 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 20.05 per share. | 01 Aug 2024 | 945 | 94,306 (0%) | 0% | 20.0 | 18,947 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.75 per share. | 01 Aug 2024 | 305 | 95,251 (0%) | 0% | 20.8 | 6,329 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 28.25 per share. | 28 Jun 2024 | 2,836 | 95,556 (0%) | 0% | 28.3 | 80,117 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 28.46 per share. | 28 Jun 2024 | 914 | 98,392 (0%) | 0% | 28.5 | 26,012 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 24.33 per share. | 28 Jun 2024 | 437 | 99,306 (0%) | 0% | 24.3 | 10,634 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 24.38 per share. | 28 Jun 2024 | 160 | 116,199 (0%) | 0% | 24.4 | 3,900 | Common Stock |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 16,552 (0%) | 0% | 0 | Common Stock | |
| Paul J. Hastings | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 13,604 (0%) | 0% | 0 | Common Stock | |
| Paul J. Hastings | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Paul J. Hastings | Director | Sale of securities on an exchange or to another person at price $ 28.38 per share. | 12 Jun 2024 | 880 | 12,724 (0%) | 0% | 28.4 | 24,974 | Common Stock |
| Charles A. Reinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,220 | 51,867 (0%) | 0% | 0 | Common Stock | |
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 21,360 | 42,045 (0%) | 0% | 0 | Common Stock | |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 28.72 per share. | 12 Jun 2024 | 3,970 | 38,075 (0%) | 0% | 28.7 | 114,018 | Common Stock |
| Mark A. Kronenfeld | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 24,902 (0%) | 0% | 0 | Common Stock | |
| Mark A. Kronenfeld | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 54,300 | 110,364 (0%) | 0% | 0 | Common Stock | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 28.38 per share. | 12 Jun 2024 | 7,452 | 102,912 (0%) | 0% | 28.4 | 211,488 | Common Stock |
| Michael J. Yang | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Michael J. Yang | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 5,230 (0%) | 0% | 0 | Common Stock | |
| Mark I. Froimson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 13,073 (0%) | 0% | 0 | Common Stock | |
| Mark I. Froimson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Abraham N. Ceesay | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Abraham N. Ceesay | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 5,230 (0%) | 0% | 0 | Common Stock | |
| Christopher J. Christie | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Christopher J. Christie | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 10,491 (0%) | 0% | 0 | Common Stock | |
| Alethia Young | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Alethia Young | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 5,230 (0%) | 0% | 0 | Common Stock | |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 54,300 | 117,039 (0%) | 0% | 0 | Common Stock | |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 28.38 per share. | 12 Jun 2024 | 1,000 | 116,039 (0%) | 0% | 28.4 | 28,380 | Common Stock |
| Marcelo Bigal | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 12,179 | 12,179 | - | - | Stock Option (Right to Buy) | |
| Marcelo Bigal | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 5,230 | 5,230 (0%) | 0% | 0 | Common Stock | |
| Jonathan Slonin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 28.57 per share. | 11 Jun 2024 | 5,012 | 44,569 (0%) | 0% | 28.6 | 143,193 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 54,300 | 98,869 (0%) | 0% | 0 | Common Stock | |
| Charles A. Reinhart | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.89 per share. | 03 Jun 2024 | 2,979 | 39,647 (0%) | 0% | 30.9 | 92,021 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.89 per share. | 03 Jun 2024 | 1,843 | 20,685 (0%) | 0% | 30.9 | 56,930 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.89 per share. | 03 Jun 2024 | 3,011 | 56,064 (0%) | 0% | 30.9 | 93,010 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.89 per share. | 03 Jun 2024 | 1,615 | 49,581 (0%) | 0% | 30.9 | 49,887 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.89 per share. | 03 Jun 2024 | 2,754 | 62,739 (0%) | 0% | 30.9 | 85,071 | Common Stock |
| Gary W. Pace | Director | Sale of securities on an exchange or to another person at price $ 30.60 per share. | 06 Mar 2024 | 90,000 | 22,127 (0%) | 0% | 30.6 | 2,754,000 | Common Stock |
| Gary W. Pace | Director | Sale of securities on an exchange or to another person at price $ 30.81 per share. | 06 Mar 2024 | 28,257 | 112,127 (0%) | 0% | 30.8 | 870,598 | Common Stock |
| Gary W. Pace | Director | Sale of securities on an exchange or to another person at price $ 29.67 per share. | 06 Mar 2024 | 1,066 | 140,384 (0%) | 0% | 29.7 | 31,628 | Common Stock |
| Marie Kristen Williams | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2024 | 33,700 | 59,075 (0%) | 0% | 0 | Common Stock | |
| Gaugler Daryl | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2024 | 33,700 | 65,493 (0%) | 0% | 0 | Common Stock | |
| Lee Frank D. | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 692,512 | 692,512 | - | - | Stock Option (Right to Buy) | |
| Jonathan Slonin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 5,000 | 51,196 (0%) | 0% | 0 | Common Stock | |
| Lee Frank D. | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 99,520 | 99,520 (0%) | 0% | 0 | Common Stock | |
| Riker Lauren | Senior Vice President, Finance | Payment of exercise price or tax liability using portion of securities received from the company at price $ 32.00 per share. | 02 Jan 2024 | 159 | 22,528 (0%) | 0% | 32 | 5,088 | Common Stock |
| Jonathan Slonin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 32,700 | 186,481 (0%) | 0% | 0 | Common Stock | |
| David M. Stack | Director, CEO and Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 245,400 | 245,400 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 1,775 | 141,450 (0%) | 0% | 0 | Common Stock | |
| Gary W. Pace | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 12,925 | 12,925 | - | - | Stock Option (Right to Buy) | |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 1,775 | 11,322 (0%) | 0% | 0 | Common Stock | |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 12,925 | 12,925 | - | - | Stock Option (Right to Buy) | |
| Paul J. Hastings | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 1,775 | 8,374 (0%) | 0% | 0 | Common Stock | |
| Paul J. Hastings | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 12,925 | 12,925 | - | - | Stock Option (Right to Buy) | |
| Charles A. Reinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (Right to Buy) | |
| Charles A. Reinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 9,000 | 42,626 (0%) | 0% | 0 | Common Stock | |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 39.00 per share. | 14 Jun 2023 | 7 | 22,687 (0%) | 0% | 39 | 273 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 10,000 | 29,053 (0%) | 0% | 0 | Common Stock | |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 38.52 per share. | 14 Jun 2023 | 5,773 | 22,694 (0%) | 0% | 38.5 | 222,376 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 37.47 per share. | 14 Jun 2023 | 586 | 28,467 (0%) | 0% | 37.5 | 21,957 | Common Stock |
| Mark A. Kronenfeld | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 1,775 | 19,672 (0%) | 0% | 0 | Common Stock | |
| Mark A. Kronenfeld | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 12,925 | 12,925 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 10,950 | 31,842 (0%) | 0% | 0 | Common Stock | |
| Kristen Marie Williams | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 27,500 | 27,500 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 37.03 per share. | 14 Jun 2023 | 6,467 | 25,375 (0%) | 0% | 37.0 | 239,473 | Common Stock |
| Mark I. Froimson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 1,775 | 7,843 (0%) | 0% | 0 | Common Stock | |
| Mark I. Froimson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 12,925 | 12,925 | - | - | Stock Option (Right to Buy) | |
| Roy Winston | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 10,950 | 52,306 (0%) | 0% | 0 | Common Stock | |
| Roy Winston | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 27,500 | 27,500 | - | - | Stock Option (Right to Buy) | |
| Christopher J. Christie | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 1,775 | 5,261 (0%) | 0% | 0 | Common Stock | |
| Christopher J. Christie | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 12,925 | 12,925 | - | - | Stock Option (Right to Buy) | |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2023 | 10,000 | 31,539 (0%) | 0% | 0 | Common Stock | |
| Mark A. Kronenfeld | Director | Sale of securities on an exchange or to another person at price $ 37.04 per share. | 08 Jun 2023 | 15,000 | 17,897 (0%) | 0% | 37.0 | 555,600 | Common Stock |
| Mark A. Kronenfeld | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jun 2023 | 15,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Mark A. Kronenfeld | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.90 per share. | 08 Jun 2023 | 15,000 | 32,897 (0%) | 0% | 29.9 | 448,500 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 06 Jun 2023 | 5,326 | 153,781 (0%) | 0% | 37.9 | 201,669 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 5,058 | 159,107 (0%) | 0% | 39.0 | 197,216 | Common Stock |
| Charles A. Reinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 06 Jun 2023 | 1,371 | 33,626 (0%) | 0% | 37.9 | 51,913 | Common Stock |
| Charles A. Reinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 1,236 | 34,997 (0%) | 0% | 39.0 | 48,193 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 06 Jun 2023 | 616 | 19,053 (0%) | 0% | 37.9 | 23,325 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 591 | 19,669 (0%) | 0% | 39.0 | 23,044 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 1,301 | 22,249 (0%) | 0% | 39.0 | 50,727 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 06 Jun 2023 | 1,357 | 20,892 (0%) | 0% | 37.9 | 51,383 | Common Stock |
| Dennis McLoughlin | Chief Customer Officer | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 1,014 | 39,172 (0%) | 0% | 39.0 | 39,537 | Common Stock |
| Dennis McLoughlin | Chief Customer Officer | Sale of securities on an exchange or to another person at price $ 37.86 per share. | 06 Jun 2023 | 1,057 | 38,115 (0%) | 0% | 37.9 | 40,023 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 1,779 | 43,213 (0%) | 0% | 39.0 | 69,365 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 37.86 per share. | 06 Jun 2023 | 1,857 | 41,356 (0%) | 0% | 37.9 | 70,315 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 06 Jun 2023 | 1,099 | 29,225 (0%) | 0% | 37.9 | 41,614 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 1,054 | 30,324 (0%) | 0% | 39.0 | 41,097 | Common Stock |
| Ronald Ellis | Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 1,114 | 32,071 (0%) | 0% | 39.0 | 43,436 | Common Stock |
| Ronald Ellis | Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 37.86 per share. | 06 Jun 2023 | 1,162 | 30,909 (0%) | 0% | 37.9 | 43,999 | Common Stock |
| Jonathan Slonin | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 06 Jun 2023 | 490 | 36,323 (0%) | 0% | 37.9 | 18,554 | Common Stock |
| Jonathan Slonin | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 06 Jun 2023 | 471 | 36,813 (0%) | 0% | 39.0 | 18,365 | Common Stock |
| Laura A. Brege | Director | Sale of securities on an exchange or to another person at price $ 38.74 per share. | 05 Jun 2023 | 600 | 9,547 (0%) | 0% | 38.7 | 23,244 | Common Stock |
| Paul J. Hastings | Director | Sale of securities on an exchange or to another person at price $ 38.34 per share. | 05 Jun 2023 | 580 | 6,599 (0%) | 0% | 38.3 | 22,237 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 38.28 per share. | 05 Jun 2023 | 2,267 | 17,398 (0%) | 0% | 38.3 | 86,774 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 38.55 per share. | 05 Jun 2023 | 4,521 | 12,877 (0%) | 0% | 38.6 | 174,285 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 38.74 per share. | 05 Jun 2023 | 1,000 | 23,591 (0%) | 0% | 38.7 | 38,740 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 05 Jun 2023 | 1,047 | 21,539 (0%) | 0% | 37.9 | 39,645 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 38.99 per share. | 05 Jun 2023 | 1,005 | 22,586 (0%) | 0% | 39.0 | 39,186 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 May 2023 | 2,500 | 0 | - | - | Stock Option (Right to Buy) | |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 39.08 per share. | 31 May 2023 | 2,500 | 24,591 (0%) | 0% | 39.1 | 97,700 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 34.00 per share. | 31 May 2023 | 2,500 | 26,894 (0%) | 0% | 34 | 85,000 | Common Stock |
| Paul J. Hastings | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 7,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Paul J. Hastings | Director | Sale of securities on an exchange or to another person at price $ 41.85 per share. | 15 May 2023 | 7,000 | 7,179 (0%) | 0% | 41.9 | 292,950 | Common Stock |
| Paul J. Hastings | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.90 per share. | 15 May 2023 | 7,000 | 14,179 (0%) | 0% | 29.9 | 209,300 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.90 per share. | 11 May 2023 | 7,000 | 144,690 (0%) | 0% | 29.9 | 209,300 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2023 | 7,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Sale of securities on an exchange or to another person at price $ 41.78 per share. | 11 May 2023 | 5,015 | 139,675 (0%) | 0% | 41.8 | 209,527 | Common Stock |
| Laura A. Brege | Director | Sale of securities on an exchange or to another person at price $ 40.72 per share. | 03 Apr 2023 | 7,000 | 10,147 (0%) | 0% | 40.7 | 285,040 | Common Stock |
| Laura A. Brege | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Apr 2023 | 7,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Laura A. Brege | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.90 per share. | 03 Apr 2023 | 7,000 | 17,147 (0%) | 0% | 29.9 | 209,300 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 39.09 per share. | 04 Jan 2023 | 158 | 19,996 (0%) | 0% | 39.1 | 6,177 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 38.31 per share. | 04 Jan 2023 | 546 | 19,450 (0%) | 0% | 38.3 | 20,917 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 58.00 per share. | 07 Oct 2022 | 1,380 | 31,378 (0%) | 0% | 58 | 80,040 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 55.70 per share. | 03 Aug 2022 | 476 | 44,992 (0%) | 0% | 55.7 | 26,513 | Common Stock |
| Jonathan Slonin | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 55.70 per share. | 03 Aug 2022 | 308 | 37,079 (0%) | 0% | 55.7 | 17,156 | Common Stock |
| Paul J. Hastings | Director | Sale of securities on an exchange or to another person at price $ 56.95 per share. | 11 Jul 2022 | 533 | 7,179 (0%) | 0% | 56.9 | 30,354 | Common Stock |
| Jonathan Slonin | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 57.19 per share. | 05 Jul 2022 | 924 | 37,387 (0%) | 0% | 57.2 | 52,842 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2022 | 6,000 | 9,000 | - | - | Stock Option (Right to Buy) | |
| Charles Anthony Laranjeira | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 14 Jun 2022 | 6,000 | 41,752 (0%) | 0% | 38.4 | 230,100 | Common Stock |
| Gary W. Pace | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 1,160 | 137,690 (0%) | 0% | 0 | Common Stock | |
| Gary W. Pace | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 8,225 | 8,225 | - | - | Stock Option (Right to Buy) | |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 8,225 | 8,225 | - | - | Stock Option (Right to Buy) | |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 1,160 | 10,147 (0%) | 0% | 0 | Common Stock | |
| Yvonne L Greenstreet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 8,225 | 8,225 | - | - | Stock Option (Right to Buy) | |
| Yvonne L Greenstreet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 1,160 | 13,247 (0%) | 0% | 0 | Common Stock | |
| Paul J. Hastings | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 8,225 | 8,225 | - | - | Stock Option (Right to Buy) | |
| Paul J. Hastings | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 1,160 | 7,712 (0%) | 0% | 0 | Common Stock | |
| Mark A. Kronenfeld | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 1,160 | 17,897 (0%) | 0% | 0 | Common Stock | |
| Mark A. Kronenfeld | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 8,225 | 8,225 | - | - | Stock Option (Right to Buy) | |
| Christopher J. Christie | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 1,160 | 3,486 (0%) | 0% | 0 | Common Stock | |
| Christopher J. Christie | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 8,225 | 8,225 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 59.10 per share. | 06 Jun 2022 | 7,039 | 149,040 (0%) | 0% | 59.1 | 416,005 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 160,900 | 160,900 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 21,500 | 163,751 (0%) | 0% | 0 | Common Stock | |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 61.96 per share. | 06 Jun 2022 | 501 | 142,251 (0%) | 0% | 62.0 | 31,042 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 61.31 per share. | 06 Jun 2022 | 1,282 | 142,752 (0%) | 0% | 61.3 | 78,599 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 60.33 per share. | 06 Jun 2022 | 5,006 | 144,034 (0%) | 0% | 60.3 | 302,012 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 11,965 | 156,079 (0%) | 0% | 61.4 | 734,340 | Common Stock |
| Charles A. Reinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 7,950 | 36,233 (0%) | 0% | 0 | Common Stock | |
| Charles A. Reinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 19,900 | 19,900 | - | - | Stock Option (Right to Buy) | |
| Charles A. Reinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 2,516 | 28,283 (0%) | 0% | 61.4 | 154,417 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 9,900 | 35,752 (0%) | 0% | 0 | Common Stock | |
| Charles Anthony Laranjeira | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 2,813 | 30,789 (0%) | 0% | 61.4 | 172,645 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 59.08 per share. | 06 Jun 2022 | 2,521 | 28,268 (0%) | 0% | 59.1 | 148,941 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 60.23 per share. | 06 Jun 2022 | 1,633 | 26,635 (0%) | 0% | 60.2 | 98,356 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 60.99 per share. | 06 Jun 2022 | 516 | 26,119 (0%) | 0% | 61.0 | 31,471 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 61.98 per share. | 06 Jun 2022 | 267 | 25,852 (0%) | 0% | 62.0 | 16,549 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 24,800 | 24,800 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 1,150 | 14,002 (0%) | 0% | 61.4 | 70,580 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 5,850 | 19,852 (0%) | 0% | 0 | Common Stock | |
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 14,600 | 14,600 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 24,800 | 24,800 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 59.51 per share. | 06 Jun 2022 | 4,649 | 13,650 (0%) | 0% | 59.5 | 276,662 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 3,969 | 18,299 (0%) | 0% | 61.4 | 243,593 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 9,900 | 23,550 (0%) | 0% | 0 | Common Stock | |
| Mark I. Froimson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 1,160 | 6,068 (0%) | 0% | 0 | Common Stock | |
| Mark I. Froimson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 8,225 | 8,225 | - | - | Stock Option (Right to Buy) | |
| Dennis McLoughlin | Chief Customer Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 2,140 | 31,820 (0%) | 0% | 61.4 | 131,340 | Common Stock |
| Dennis McLoughlin | Chief Customer Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 19,900 | 19,900 | - | - | Stock Option (Right to Buy) | |
| Dennis McLoughlin | Chief Customer Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 7,950 | 39,770 (0%) | 0% | 0 | Common Stock | |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 62.43 per share. | 06 Jun 2022 | 1,300 | 44,472 (0%) | 0% | 62.4 | 81,159 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 61.59 per share. | 06 Jun 2022 | 2,300 | 45,772 (0%) | 0% | 61.6 | 141,657 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 60.55 per share. | 06 Jun 2022 | 2,535 | 48,072 (0%) | 0% | 60.5 | 153,494 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 2,099 | 44,357 (0%) | 0% | 61.4 | 128,824 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 63.40 per share. | 06 Jun 2022 | 115 | 44,357 (0%) | 0% | 63.4 | 7,291 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 60.55 per share. | 06 Jun 2022 | 3,533 | 40,824 (0%) | 0% | 60.5 | 213,923 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 61.59 per share. | 06 Jun 2022 | 3,650 | 37,174 (0%) | 0% | 61.6 | 224,804 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 62.48 per share. | 06 Jun 2022 | 1,891 | 35,283 (0%) | 0% | 62.5 | 118,150 | Common Stock |
| Roy Winston | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 63.69 per share. | 06 Jun 2022 | 123 | 35,160 (0%) | 0% | 63.7 | 7,834 | Common Stock |
| Roy Winston | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 9,900 | 45,060 (0%) | 0% | 0 | Common Stock | |
| Roy Winston | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2022 | 6,250 | 0 | - | - | Stock Option (Right to Buy) | |
| Roy Winston | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 24,800 | 24,800 | - | - | Stock Option (Right to Buy) | |
| Roy Winston | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 34.38 per share. | 06 Jun 2022 | 6,250 | 50,607 (0%) | 0% | 34.4 | 214,844 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 2,817 | 26,833 (0%) | 0% | 61.4 | 172,891 | Common Stock |
| Max Reinhardt | President, Rest of World | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 7,950 | 32,250 (0%) | 0% | 0 | Common Stock | |
| Max Reinhardt | President, Rest of World | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 19,900 | 19,900 | - | - | Stock Option (Right to Buy) | |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 62.00 per share. | 06 Jun 2022 | 2,433 | 24,400 (0%) | 0% | 62 | 150,846 | Common Stock |
| Jonathan Slonin | Chief Clinical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 9,900 | 38,097 (0%) | 0% | 0 | Common Stock | |
| Jonathan Slonin | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Jun 2022 | 24,800 | 24,800 | - | - | Stock Option (Right to Buy) | |
| Jonathan Slonin | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 362 | 28,197 (0%) | 0% | 61.4 | 22,217 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 19,900 | 19,900 | - | - | Stock Option (Right to Buy) | |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 2,980 | 14,570 (0%) | 0% | 61.4 | 182,895 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 59.38 per share. | 06 Jun 2022 | 740 | 13,830 (0%) | 0% | 59.4 | 43,941 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 60.40 per share. | 06 Jun 2022 | 1,830 | 12,000 (0%) | 0% | 60.4 | 110,532 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 7,950 | 19,950 (0%) | 0% | 0 | Common Stock | |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 5,000 | 24,394 (0%) | 0% | 0 | Common Stock | |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 7,900 | 19,394 (0%) | 0% | 0 | Common Stock | |
| Daryl Gaugler | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 61.37 per share. | 06 Jun 2022 | 1,106 | 11,494 (0%) | 0% | 61.4 | 67,880 | Common Stock |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 19,800 | 19,800 | - | - | Stock Option (Right to Buy) | |
| Daryl Gaugler | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2022 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Jonathan Slonin | Chief Clinical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 52.37 per share. | 23 May 2022 | 2,000 | 28,559 (0%) | 0% | 52.4 | 104,740 | Common Stock |
| Jonathan Slonin | Chief Clinical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 May 2022 | 2,000 | 35,500 | - | - | Stock Option (Right to Buy) | |
| Mark I. Froimson | Director | Sale of securities on an exchange or to another person at price $ 59.37 per share. | 09 May 2022 | 1,000 | 4,908 (0%) | 0% | 59.4 | 59,370 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Apr 2022 | 22,500 | 0 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 28 Apr 2022 | 22,500 | 168,044 (0%) | 0% | 10.8 | 243,225 | Common Stock |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.54 per share. | 21 Apr 2022 | 12,500 | 39,474 (0%) | 0% | 42.5 | 531,750 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 73.25 per share. | 21 Apr 2022 | 9,824 | 29,650 (0%) | 0% | 73.3 | 719,647 | Common Stock |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Apr 2022 | 12,500 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.54 per share. | 18 Apr 2022 | 12,500 | 30,000 (0%) | 0% | 42.5 | 531,750 | Common Stock |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Apr 2022 | 12,500 | 112,500 | - | - | Stock Option (Right to Buy) | |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Apr 2022 | 12,500 | 125,000 | - | - | Stock Option (Right to Buy) | |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Apr 2022 | 12,500 | 137,500 | - | - | Stock Option (Right to Buy) | |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 73.99 per share. | 18 Apr 2022 | 9,764 | 26,974 (0%) | 0% | 74.0 | 722,438 | Common Stock |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.54 per share. | 18 Apr 2022 | 12,500 | 36,738 (0%) | 0% | 42.5 | 531,750 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 72.25 per share. | 18 Apr 2022 | 9,321 | 24,238 (0%) | 0% | 72.2 | 673,442 | Common Stock |
| Max Reinhardt | President, Rest of World | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.54 per share. | 18 Apr 2022 | 12,500 | 33,559 (0%) | 0% | 42.5 | 531,750 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 73.55 per share. | 18 Apr 2022 | 8,941 | 21,059 (0%) | 0% | 73.6 | 657,611 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Apr 2022 | 7,000 | 1,750 | - | - | Stock Option (Right to Buy) | |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Apr 2022 | 2,500 | 625 | - | - | Stock Option (Right to Buy) | |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Apr 2022 | 10,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Apr 2022 | 3,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 77.94 per share. | 06 Apr 2022 | 2,503 | 17,550 (0%) | 0% | 77.9 | 195,084 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 77.03 per share. | 06 Apr 2022 | 3,937 | 20,053 (0%) | 0% | 77.0 | 303,267 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 76.03 per share. | 06 Apr 2022 | 16,060 | 23,990 (0%) | 0% | 76.0 | 1,221,042 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 06 Apr 2022 | 7,000 | 40,050 (0%) | 0% | 38.4 | 268,450 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 34.38 per share. | 06 Apr 2022 | 2,500 | 33,050 (0%) | 0% | 34.4 | 85,938 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.20 per share. | 06 Apr 2022 | 10,000 | 30,550 (0%) | 0% | 44.2 | 442,000 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.34 per share. | 06 Apr 2022 | 3,000 | 20,550 (0%) | 0% | 40.3 | 121,020 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 31 Mar 2022 | 22,500 | 145,544 (0%) | 0% | 10.8 | 243,225 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2022 | 22,500 | 22,500 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 72.67 per share. | 21 Mar 2022 | 7,253 | 22,268 (0%) | 0% | 72.7 | 527,076 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 47.65 per share. | 21 Mar 2022 | 2,188 | 29,521 (0%) | 0% | 47.6 | 104,258 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2022 | 2,188 | 19,685 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 21 Mar 2022 | 2,953 | 25,221 (0%) | 0% | 38.4 | 113,248 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 43.54 per share. | 21 Mar 2022 | 2,112 | 27,333 (0%) | 0% | 43.5 | 91,956 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2022 | 2,112 | 10,560 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2022 | 2,953 | 2,953 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 10 Mar 2022 | 9,300 | 24,452 (0%) | 0% | 10.8 | 100,533 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 71.95 per share. | 10 Mar 2022 | 900 | 15,152 (0%) | 0% | 72.0 | 64,755 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 71.14 per share. | 10 Mar 2022 | 8,400 | 16,052 (0%) | 0% | 71.1 | 597,576 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2022 | 9,300 | 0 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 03 Mar 2022 | 7,000 | 136,530 (0%) | 0% | 10.8 | 75,670 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2022 | 7,000 | 0 | - | - | Stock Option (Right to Buy) | |
| John P. Longenecker | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2022 | 7,000 | 0 | - | - | Stock Option (Right to Buy) | |
| John P. Longenecker | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 03 Mar 2022 | 7,000 | 25,823 (0%) | 0% | 10.8 | 75,670 | Common Stock |
| John P. Longenecker | Director | Sale of securities on an exchange or to another person at price $ 71.74 per share. | 03 Mar 2022 | 7,000 | 18,823 (0%) | 0% | 71.7 | 502,145 | Common Stock |
| Gary W. Pace | Director | Sale of securities on an exchange or to another person at price $ 66.83 per share. | 28 Feb 2022 | 28,641 | 129,530 (0%) | 0% | 66.8 | 1,914,078 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2022 | 1,166 | 0 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2022 | 193 | 0 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2022 | 18,834 | 1,166 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2022 | 9,807 | 193 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Sale of securities on an exchange or to another person at price $ 67.75 per share. | 28 Feb 2022 | 1,359 | 129,530 (0%) | 0% | 67.7 | 92,072 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.02 per share. | 28 Feb 2022 | 1,166 | 130,889 (0%) | 0% | 11.0 | 12,849 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.02 per share. | 28 Feb 2022 | 193 | 129,723 (0%) | 0% | 11.0 | 2,127 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.02 per share. | 28 Feb 2022 | 18,834 | 158,171 (0%) | 0% | 11.0 | 207,551 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.02 per share. | 28 Feb 2022 | 9,807 | 139,337 (0%) | 0% | 11.0 | 108,073 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 67.07 per share. | 16 Feb 2022 | 2,000 | 22,268 (0%) | 0% | 67.1 | 134,140 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 65.00 per share. | 16 Feb 2022 | 50 | 24,268 (0%) | 0% | 65 | 3,250 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 16 Feb 2022 | 2,050 | 24,318 (0%) | 0% | 38.4 | 78,618 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 65.00 per share. | 16 Feb 2022 | 10 | 22,268 (0%) | 0% | 65 | 650 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.40 per share. | 16 Feb 2022 | 10 | 22,278 (0%) | 0% | 38.4 | 384 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2022 | 2,050 | 5,906 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2022 | 10 | 7,956 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 65.18 per share. | 10 Feb 2022 | 800 | 22,268 (0%) | 0% | 65.2 | 52,144 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 10 Feb 2022 | 800 | 23,068 (0%) | 0% | 38.4 | 30,680 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2022 | 800 | 7,966 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 65.18 per share. | 04 Feb 2022 | 1,000 | 22,268 (0%) | 0% | 65.2 | 65,180 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 04 Feb 2022 | 1,000 | 23,268 (0%) | 0% | 38.4 | 38,350 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Feb 2022 | 1,000 | 8,766 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 25 Jan 2022 | 13,670 | 123,044 (0%) | 0% | 10.8 | 147,773 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jan 2022 | 13,670 | 45,000 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 21 Jan 2022 | 200 | 22,468 (0%) | 0% | 38.4 | 7,670 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Jan 2022 | 200 | 9,766 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 65.41 per share. | 21 Jan 2022 | 200 | 22,268 (0%) | 0% | 65.4 | 13,082 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 18 Jan 2022 | 2,500 | 17,652 (0%) | 0% | 10.8 | 27,025 | Common Stock |
| Lauren Riker | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jan 2022 | 2,500 | 9,300 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 64.97 per share. | 18 Jan 2022 | 2,500 | 15,152 (0%) | 0% | 65.0 | 162,430 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 18 Jan 2022 | 2,199 | 24,467 (0%) | 0% | 38.4 | 84,332 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jan 2022 | 2,199 | 9,966 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jan 2022 | 13,127 | 21,873 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jan 2022 | 6,338 | 12,672 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jan 2022 | 2,600 | 12,165 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jan 2022 | 1,375 | 0 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 65.51 per share. | 18 Jan 2022 | 2,199 | 22,268 (0%) | 0% | 65.5 | 144,056 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 66.14 per share. | 18 Jan 2022 | 400 | 22,268 (0%) | 0% | 66.1 | 26,456 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 65.24 per share. | 18 Jan 2022 | 23,040 | 22,668 (0%) | 0% | 65.2 | 1,503,130 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 47.65 per share. | 18 Jan 2022 | 13,127 | 45,708 (0%) | 0% | 47.7 | 625,502 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 43.54 per share. | 18 Jan 2022 | 6,338 | 32,581 (0%) | 0% | 43.5 | 275,957 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 18 Jan 2022 | 2,600 | 26,243 (0%) | 0% | 38.4 | 99,710 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.20 per share. | 18 Jan 2022 | 1,375 | 23,643 (0%) | 0% | 44.2 | 60,775 | Common Stock |
| Anthony Molloy | Chief Lgl & Compliance Officer | Sale of securities on an exchange or to another person at price $ 63.55 per share. | 18 Jan 2022 | 224 | 17,550 (0%) | 0% | 63.5 | 14,235 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 11 Jan 2022 | 15,000 | 109,374 (0%) | 0% | 10.8 | 162,150 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Jan 2022 | 15,000 | 58,670 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2022 | 2,000 | 15,152 (0%) | 0% | 0 | Common Stock | |
| Lauren Riker | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2022 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| Anthony Molloy | Chief Lgl & Compliance Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2022 | 2,000 | 17,774 (0%) | 0% | 0 | Common Stock | |
| Anthony Molloy | Chief Lgl & Compliance Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2022 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| Mark I. Froimson | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Dec 2021 | 400 | 5,908 (0%) | 0% | 0 | Common Stock | |
| Charles Anthony Laranjeira | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.10 per share. | 22 Nov 2021 | 7,500 | 33,602 (0%) | 0% | 44.1 | 330,750 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Nov 2021 | 7,500 | 0 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 16 Nov 2021 | 15,000 | 94,085 (0%) | 0% | 10.8 | 162,150 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2021 | 15,000 | 73,670 | - | - | Stock Option (Right to Buy) | |
| Roy Winston | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Nov 2021 | 10,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Roy Winston | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 48.15 per share. | 04 Nov 2021 | 10,000 | 46,456 (0%) | 0% | 48.2 | 481,500 | Common Stock |
| Roy Winston | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 5,000 | 36,456 (0%) | 0% | 0 | Common Stock | |
| Roy Winston | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Jonathan Slonin | Chief Clinical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Jonathan Slonin | Chief Clinical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 5,000 | 26,350 (0%) | 0% | 0 | Common Stock | |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 60.85 per share. | 28 Jul 2021 | 2,410 | 13,152 (0%) | 0% | 60.9 | 146,649 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jul 2021 | 90 | 11,800 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jul 2021 | 2,410 | 11,890 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 60.81 per share. | 28 Jul 2021 | 90 | 13,152 (0%) | 0% | 60.8 | 5,473 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 28 Jul 2021 | 90 | 13,242 (0%) | 0% | 10.8 | 973 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 28 Jul 2021 | 2,410 | 15,562 (0%) | 0% | 10.8 | 26,052 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 59.76 per share. | 02 Jul 2021 | 421 | 17,500 (0%) | 0% | 59.8 | 25,159 | Common Stock |
| Donald C. Manning | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 61.14 per share. | 08 Jun 2021 | 2,600 | 23,520 (0%) | 0% | 61.1 | 158,964 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 14,905 | 61,156 (0%) | 0% | 61.0 | 909,756 | Common Stock |
| Paul J. Hastings | Director | Sale of securities on an exchange or to another person at price $ 62.19 per share. | 04 Jun 2021 | 630 | 5,486 (0%) | 0% | 62.2 | 39,180 | Common Stock |
| Charles A. Reinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 2,648 | 24,799 (0%) | 0% | 61.0 | 161,626 | Common Stock |
| Charles Anthony Laranjeira | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 2,117 | 18,681 (0%) | 0% | 61.0 | 129,215 | Common Stock |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 1,047 | 12,134 (0%) | 0% | 61.0 | 63,906 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 3,930 | 20,957 (0%) | 0% | 61.0 | 239,875 | Common Stock |
| Dennis McLoughlin | Chief Customer Officer | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 1,895 | 27,541 (0%) | 0% | 61.0 | 115,665 | Common Stock |
| Roy Winston | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 2,276 | 24,035 (0%) | 0% | 61.0 | 138,920 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 60.50 per share. | 04 Jun 2021 | 2,278 | 10,500 (0%) | 0% | 60.5 | 137,819 | Common Stock |
| Max Reinhardt | President, Rest of World | Sale of securities on an exchange or to another person at price $ 61.04 per share. | 04 Jun 2021 | 1,222 | 12,778 (0%) | 0% | 61.0 | 74,587 | Common Stock |
| Donald C. Manning | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 62.12 per share. | 02 Jun 2021 | 2,380 | 26,120 (0%) | 0% | 62.1 | 147,853 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 32.35 per share. | 13 Apr 2021 | 2,500 | 27,387 (0%) | 0% | 32.4 | 80,875 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.20 per share. | 13 Apr 2021 | 4,125 | 31,512 (0%) | 0% | 44.2 | 182,325 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 13 Apr 2021 | 8,859 | 40,371 (0%) | 0% | 38.4 | 339,743 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 43.54 per share. | 13 Apr 2021 | 6,339 | 46,710 (0%) | 0% | 43.5 | 276,000 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 66.40 per share. | 13 Apr 2021 | 14,793 | 31,917 (0%) | 0% | 66.4 | 982,255 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 68.11 per share. | 13 Apr 2021 | 7,030 | 24,887 (0%) | 0% | 68.1 | 478,813 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Apr 2021 | 2,500 | 0 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Apr 2021 | 4,125 | 1,375 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Apr 2021 | 8,859 | 14,765 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Apr 2021 | 6,339 | 19,010 | - | - | Stock Option (Right to Buy) | |
| Roy Winston | Chief Clinical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 34.37 per share. | 31 Mar 2021 | 13,750 | 48,535 (0%) | 0% | 34.4 | 472,656 | Common Stock |
| Roy Winston | Chief Clinical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2021 | 13,750 | 6,250 | - | - | Stock Option (Right to Buy) | |
| Roy Winston | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 72.12 per share. | 31 Mar 2021 | 1,200 | 26,311 (0%) | 0% | 72.1 | 86,544 | Common Stock |
| Roy Winston | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 71.09 per share. | 31 Mar 2021 | 4,661 | 27,511 (0%) | 0% | 71.1 | 331,350 | Common Stock |
| Roy Winston | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 70.36 per share. | 31 Mar 2021 | 16,363 | 32,172 (0%) | 0% | 70.4 | 1,151,301 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Mar 2021 | 21,250 | 109,920 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Mar 2021 | 21,250 | 88,670 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 60.78 per share. | 24 Mar 2021 | 13,318 | 83,993 (0%) | 0% | 60.8 | 809,468 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 24 Mar 2021 | 21,250 | 97,311 (0%) | 0% | 10.8 | 229,713 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Mar 2021 | 1,080 | 97,273 (0%) | 0% | 0 | Common Stock | |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 61.19 per share. | 24 Mar 2021 | 7,932 | 76,061 (0%) | 0% | 61.2 | 485,359 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 24 Mar 2021 | 21,250 | 97,311 (0%) | 0% | 10.8 | 229,713 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 60.76 per share. | 24 Mar 2021 | 2,970 | 94,341 (0%) | 0% | 60.8 | 180,457 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 62.08 per share. | 24 Mar 2021 | 14,669 | 79,672 (0%) | 0% | 62.1 | 910,652 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 62.41 per share. | 24 Mar 2021 | 3,611 | 76,061 (0%) | 0% | 62.4 | 225,363 | Common Stock |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 73.28 per share. | 15 Mar 2021 | 1,520 | 13,181 (0%) | 0% | 73.3 | 111,386 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2021 | 2,000 | 14,300 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2021 | 1,520 | 16,300 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 70.01 per share. | 15 Mar 2021 | 2,000 | 13,181 (0%) | 0% | 70.0 | 140,020 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 15 Mar 2021 | 2,000 | 15,181 (0%) | 0% | 10.8 | 21,620 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 15 Mar 2021 | 1,520 | 14,701 (0%) | 0% | 10.8 | 16,431 | Common Stock |
| Mark I. Froimson | Director | Sale of securities on an exchange or to another person at price $ 72.26 per share. | 15 Mar 2021 | 734 | 5,242 (0%) | 0% | 72.3 | 53,039 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 73.68 per share. | 12 Mar 2021 | 10,601 | 451,324 (1%) | 0% | 73.7 | 781,082 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 73.10 per share. | 12 Mar 2021 | 58,754 | 461,925 (1%) | 0% | 73.1 | 4,294,917 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 72.70 per share. | 09 Mar 2021 | 60,574 | 520,679 (1%) | 0% | 72.7 | 4,403,730 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 71.78 per share. | 09 Mar 2021 | 76,480 | 581,253 (1%) | 0% | 71.8 | 5,489,734 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 70.90 per share. | 09 Mar 2021 | 35,137 | 657,733 (1%) | 0% | 70.9 | 2,491,213 | Common Stock |
| Paul J. Hastings | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 3,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Paul J. Hastings | Director | Sale of securities on an exchange or to another person at price $ 65.88 per share. | 05 Mar 2021 | 3,000 | 6,116 (0%) | 0% | 65.9 | 197,640 | Common Stock |
| Paul J. Hastings | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.98 per share. | 05 Mar 2021 | 3,000 | 9,116 (0%) | 0% | 14.0 | 41,940 | Common Stock |
| John P. Longenecker | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 5,000 | 0 | - | - | Stock Option (Right to Buy) | |
| John P. Longenecker | Director | Sale of securities on an exchange or to another person at price $ 72.26 per share. | 01 Mar 2021 | 5,000 | 17,757 (0%) | 0% | 72.3 | 361,300 | Common Stock |
| John P. Longenecker | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.98 per share. | 01 Mar 2021 | 5,000 | 22,757 (0%) | 0% | 14.0 | 69,900 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 68.41 per share. | 02 Feb 2021 | 2,900 | 94,411 (0%) | 0% | 68.4 | 198,389 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 02 Feb 2021 | 21,250 | 97,311 (0%) | 0% | 10.8 | 229,713 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2021 | 21,250 | 131,170 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2021 | 21,250 | 152,420 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 71.42 per share. | 02 Feb 2021 | 14,350 | 76,061 (0%) | 0% | 71.4 | 1,024,877 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 70.78 per share. | 02 Feb 2021 | 6,900 | 90,411 (0%) | 0% | 70.8 | 488,382 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 02 Feb 2021 | 21,250 | 97,311 (0%) | 0% | 10.8 | 229,713 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 70.20 per share. | 02 Feb 2021 | 4,100 | 76,061 (0%) | 0% | 70.2 | 287,820 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 69.38 per share. | 02 Feb 2021 | 14,250 | 80,161 (0%) | 0% | 69.4 | 988,665 | Common Stock |
| Max Reinhardt | President | Sale of securities on an exchange or to another person at price $ 60.81 per share. | 06 Jan 2021 | 110 | 14,000 (0%) | 0% | 60.8 | 6,689 | Common Stock |
| Laura Brege | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.98 per share. | 16 Nov 2020 | 12,000 | 19,921 (0%) | 0% | 14.0 | 167,760 | Common Stock |
| Laura Brege | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2020 | 12,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Laura Brege | Director | Sale of securities on an exchange or to another person at price $ 65.95 per share. | 16 Nov 2020 | 12,000 | 7,921 (0%) | 0% | 66.0 | 791,400 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Nov 2020 | 3,000 | 17,820 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 63.81 per share. | 13 Nov 2020 | 3,000 | 13,181 (0%) | 0% | 63.8 | 191,430 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 13 Nov 2020 | 3,000 | 16,181 (0%) | 0% | 10.8 | 32,430 | Common Stock |
| Roy Winston | Chief Clinical Officer | Sale of securities on an exchange or to another person at price $ 62.00 per share. | 13 Nov 2020 | 5,000 | 34,785 (0%) | 0% | 62 | 310,000 | Common Stock |
| Max Reinhardt | President | Sale of securities on an exchange or to another person at price $ 62.67 per share. | 13 Nov 2020 | 4,000 | 35,000 (0%) | 0% | 62.7 | 250,680 | Common Stock |
| Max Reinhardt | President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Nov 2020 | 25,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Max Reinhardt | President | Sale of securities on an exchange or to another person at price $ 63.51 per share. | 13 Nov 2020 | 21,000 | 14,000 (0%) | 0% | 63.5 | 1,333,710 | Common Stock |
| Max Reinhardt | President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.54 per share. | 13 Nov 2020 | 25,000 | 39,000 (0%) | 0% | 42.5 | 1,063,500 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 55.53 per share. | 14 Oct 2020 | 30,000 | 173,377 (0%) | 0% | 55.5 | 1,665,900 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Oct 2020 | 30,000 | 173,670 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Oct 2020 | 30,000 | 203,670 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Oct 2020 | 30,000 | 233,670 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 55.56 per share. | 14 Oct 2020 | 30,000 | 173,377 (0%) | 0% | 55.6 | 1,666,800 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 14 Oct 2020 | 30,000 | 203,377 (0%) | 0% | 10.8 | 324,300 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 55.00 per share. | 14 Oct 2020 | 30,000 | 173,377 (0%) | 0% | 55 | 1,650,000 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 14 Oct 2020 | 30,000 | 203,377 (0%) | 0% | 10.8 | 324,300 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 14 Oct 2020 | 30,000 | 203,377 (0%) | 0% | 10.8 | 324,300 | Common Stock |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Sep 2020 | 70,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.67 per share. | 25 Sep 2020 | 70,000 | 129,949 (0%) | 0% | 16.7 | 1,166,900 | Common Stock |
| Max Reinhardt | President | Sale of securities on an exchange or to another person at price $ 59.75 per share. | 17 Sep 2020 | 22,532 | 16,888 (0%) | 0% | 59.8 | 1,346,287 | Common Stock |
| Max Reinhardt | President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Sep 2020 | 25,000 | 175,000 | - | - | Stock Option (Right to Buy) | |
| Max Reinhardt | President | Sale of securities on an exchange or to another person at price $ 60.26 per share. | 17 Sep 2020 | 2,888 | 14,000 (0%) | 0% | 60.3 | 174,031 | Common Stock |
| Max Reinhardt | President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.54 per share. | 17 Sep 2020 | 25,000 | 39,000 (0%) | 0% | 42.5 | 1,063,500 | Common Stock |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 60.34 per share. | 16 Sep 2020 | 3,000 | 13,181 (0%) | 0% | 60.3 | 181,020 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Sep 2020 | 3,000 | 20,820 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.81 per share. | 16 Sep 2020 | 3,000 | 16,181 (0%) | 0% | 10.8 | 32,430 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 32.35 per share. | 15 Sep 2020 | 5,836 | 36,559 (0%) | 0% | 32.4 | 188,795 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 2,819 | 25,349 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 7,878 | 23,624 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,502 | 5,500 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,836 | 2,500 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,836 | 0 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 2,816 | 28,168 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 7,874 | 31,502 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,499 | 11,002 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,832 | 8,336 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,832 | 5,836 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 2,816 | 30,984 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 7,874 | 39,376 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,499 | 16,501 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,832 | 14,168 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2020 | 5,832 | 11,668 | - | - | Stock Option (Right to Buy) | |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 60.22 per share. | 15 Sep 2020 | 3,200 | 24,887 (0%) | 0% | 60.2 | 192,704 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 59.77 per share. | 15 Sep 2020 | 24,671 | 28,087 (0%) | 0% | 59.8 | 1,474,586 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 43.54 per share. | 15 Sep 2020 | 2,819 | 52,758 (0%) | 0% | 43.5 | 122,739 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 15 Sep 2020 | 7,878 | 49,939 (0%) | 0% | 38.3 | 302,121 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.20 per share. | 15 Sep 2020 | 5,502 | 42,061 (0%) | 0% | 44.2 | 243,188 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.34 per share. | 15 Sep 2020 | 5,836 | 30,723 (0%) | 0% | 40.3 | 235,424 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 60.33 per share. | 15 Sep 2020 | 21,244 | 24,887 (0%) | 0% | 60.3 | 1,281,651 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 59.54 per share. | 15 Sep 2020 | 6,609 | 46,131 (0%) | 0% | 59.5 | 393,500 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 43.54 per share. | 15 Sep 2020 | 2,816 | 52,740 (0%) | 0% | 43.5 | 122,609 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 15 Sep 2020 | 7,874 | 49,924 (0%) | 0% | 38.4 | 301,968 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.20 per share. | 15 Sep 2020 | 5,499 | 42,050 (0%) | 0% | 44.2 | 243,056 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 32.35 per share. | 15 Sep 2020 | 5,832 | 36,551 (0%) | 0% | 32.3 | 188,665 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.34 per share. | 15 Sep 2020 | 5,832 | 30,719 (0%) | 0% | 40.3 | 235,263 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 59.80 per share. | 15 Sep 2020 | 13,231 | 24,887 (0%) | 0% | 59.8 | 791,214 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 59.01 per share. | 15 Sep 2020 | 14,622 | 38,118 (0%) | 0% | 59.0 | 862,844 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 43.54 per share. | 15 Sep 2020 | 2,816 | 52,740 (0%) | 0% | 43.5 | 122,609 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 15 Sep 2020 | 7,874 | 49,924 (0%) | 0% | 38.4 | 301,968 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.20 per share. | 15 Sep 2020 | 5,499 | 42,050 (0%) | 0% | 44.2 | 243,056 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 32.35 per share. | 15 Sep 2020 | 5,832 | 36,551 (0%) | 0% | 32.3 | 188,665 | Common Stock |
| Kristen Marie Williams | Chief Administrative Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 40.34 per share. | 15 Sep 2020 | 5,832 | 30,719 (0%) | 0% | 40.3 | 235,263 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 62.02 per share. | 09 Sep 2020 | 2,216 | 692,970 (1%) | 0% | 62.0 | 137,436 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 62.34 per share. | 17 Aug 2020 | 3,217 | 173,377 (0%) | 0% | 62.3 | 200,548 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 61.79 per share. | 17 Aug 2020 | 11,783 | 176,594 (0%) | 0% | 61.8 | 728,072 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 60.82 per share. | 11 Aug 2020 | 113,500 | 730,090 (1%) | 0% | 60.8 | 6,903,070 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 60.87 per share. | 11 Aug 2020 | 60,621 | 889,741 (2%) | 0% | 60.9 | 3,690,000 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 61.47 per share. | 11 Aug 2020 | 34,904 | 695,186 (1%) | 0% | 61.5 | 2,145,549 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 61.90 per share. | 11 Aug 2020 | 46,151 | 843,590 (2%) | 0% | 61.9 | 2,856,747 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Aug 2020 | 8,180 | 0 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.34 per share. | 11 Aug 2020 | 8,180 | 20,813 (0%) | 0% | 10.3 | 84,581 | Common Stock |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 60.50 per share. | 11 Aug 2020 | 8,180 | 13,181 (0%) | 0% | 60.5 | 494,890 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Aug 2020 | 2,500 | 7,500 | - | - | Common Stock | |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.10 per share. | 03 Aug 2020 | 2,500 | 22,750 (0%) | 0% | 44.1 | 110,250 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Sale of securities on an exchange or to another person at price $ 52.68 per share. | 03 Aug 2020 | 2,500 | 20,796 (0%) | 0% | 52.7 | 131,700 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Sale of securities on an exchange or to another person at price $ 56.88 per share. | 15 Jul 2020 | 12,000 | 188,377 (0%) | 0% | 56.9 | 682,560 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Sale of securities on an exchange or to another person at price $ 52.03 per share. | 29 Jun 2020 | 1,778 | 20,250 (0%) | 0% | 52.0 | 92,509 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 37.81 per share. | 29 Jun 2020 | 3,750 | 27,851 (0%) | 0% | 37.8 | 141,788 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 38.35 per share. | 29 Jun 2020 | 15,000 | 42,851 (0%) | 0% | 38.4 | 575,250 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 43.54 per share. | 29 Jun 2020 | 7,500 | 50,351 (0%) | 0% | 43.5 | 326,550 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 44.10 per share. | 29 Jun 2020 | 30,000 | 80,351 (0%) | 0% | 44.1 | 1,323,000 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Sale of securities on an exchange or to another person at price $ 50.01 per share. | 29 Jun 2020 | 51,464 | 28,887 (0%) | 0% | 50.0 | 2,573,715 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Sale of securities on an exchange or to another person at price $ 51.77 per share. | 29 Jun 2020 | 6,859 | 22,028 (0%) | 0% | 51.8 | 355,090 | Common Stock |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jun 2020 | 3,750 | 6,250 | - | - | Stock Option (Right to Buy) | |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jun 2020 | 7,500 | 22,500 | - | - | Stock Option (Right to Buy) | |
| Charles Anthony Laranjeira | SVP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jun 2020 | 30,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 49.34 per share. | 29 Jun 2020 | 2,000 | 14,633 (0%) | 0% | 49.3 | 98,680 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jun 2020 | 6,000 | 8,180 | - | - | Stock Option (Right to Buy) | |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 50.34 per share. | 29 Jun 2020 | 2,000 | 12,633 (0%) | 0% | 50.3 | 100,680 | Common Stock |
| Lauren Riker | Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.34 per share. | 29 Jun 2020 | 6,000 | 18,633 (0%) | 0% | 10.3 | 62,040 | Common Stock |
| Lauren Riker | Vice President, Finance | Sale of securities on an exchange or to another person at price $ 48.72 per share. | 29 Jun 2020 | 2,000 | 16,633 (0%) | 0% | 48.7 | 97,440 | Common Stock |
| David M. Stack | Director, CEO and Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 275,000 | 275,000 | - | - | Stock Option (Right to Buy) | |
| David M. Stack | Director, CEO and Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 33,300 | 200,209 (0%) | 0% | 0 | Common Stock | |
| Gary W. Pace | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 8,027 | 8,027 | - | - | Stock Option (Right to Buy) | |
| Gary W. Pace | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 1,260 | 59,949 (0%) | 0% | 0 | Common Stock | |
| John P. Longenecker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 8,027 | 8,027 | - | - | Stock Option (Right to Buy) | |
| John P. Longenecker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 1,260 | 17,757 (0%) | 0% | 0 | Common Stock | |
| Laura Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 1,260 | 7,921 (0%) | 0% | 0 | Common Stock |