45,635 XNAS Volume
XNAS 20 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Edgar B. Cale | GC & CORPORATE SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2025 | 278,386 | 278,386 | - | - | Employee Stock Option (right to buy) | |
| William Chou | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2025 | 779,533 | 779,533 | - | - | Employee Stock Option (right to buy) | |
| Kathleen Borthwick | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2025 | 278,386 | 278,386 | - | - | Employee Stock Option (right to buy) | |
| Kathleen Borthwick | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2025 | 8,000 | 44,466 (0%) | 0% | - | Common Stock | |
| Kathleen Borthwick | CFO | Sale of securities on an exchange or to another person at price $ 0.53 per share. | 10 Feb 2025 | 3,183 | 41,283 (0%) | 0% | 0.5 | 1,686 | Common Stock |
| Kathleen Borthwick | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2025 | 8,000 | 0 | - | - | Restricted Stock Unit | |
| Thomas R. Kassberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 174,139 | 174,139 | - | - | Employee Stock Option (right to buy) | |
| Edgar B. Cale | GC & CORPORATE SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 50,000 | 50,000 | - | - | Employee Stock Option (right to buy) | |
| Maxine Gowen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 47,693 | 47,693 | - | - | Director Stock Option (right to buy) | |
| Saqib Islam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 47,693 | 47,693 | - | - | Director Stock Option (right to buy) | |
| Athena Countouriotis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 47,693 | 47,693 | - | - | Director Stock Option (right to buy) | |
| Sandip S. Kapadia | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 47,693 | 47,693 | - | - | Director Stock Option (right to buy) | |
| Derrell D. Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 47,693 | 47,693 | - | - | Director Stock Option (right to buy) | |
| Dolan Sondhi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 39,092 | 39,092 | - | - | Director Stock Option (right to buy) | |
| Edgar B. Cale | GC & CORPORATE SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2024 | 203,000 | 203,000 | - | - | Employee Stock Option (right to buy) | |
| Mark S. Forman | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2024 | 203,000 | 203,000 | - | - | Employee Stock Option (right to buy) | |
| William Chou | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2024 | 575,000 | 575,000 | - | - | Employee Stock Option (right to buy) | |
| Kathleen Borthwick | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2024 | 227,000 | 227,000 | - | - | Employee Stock Option (right to buy) | |
| Borthwick Kathleen | SVP, INTERIM CFO | Sale of securities on an exchange or to another person at price $ 0.97 per share. | 10 Feb 2024 | 1,470 | 28,466 (0%) | 0% | 1.0 | 1,426 | Common Stock |
| Kathleen Borthwick | SVP, INTERIM CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2024 | 4,000 | 8,000 | - | - | Restricted Stock Unit | |
| Borthwick Kathleen | SVP, INTERIM CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2024 | 4,000 | 29,936 (0%) | 0% | - | Common Stock | |
| Forman S. Mark | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2023 | 50,000 | 0 | - | - | Restricted Stock Unit | |
| Kathleen Borthwick | SVP, Interim CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2023 | 30,000 | 36,608 (0%) | 0% | - | Common Stock | |
| Kathleen Borthwick | SVP, Interim CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2023 | 30,000 | 0 | - | - | Restricted Stock Unit | |
| B. Edgar Cale | GC & Corporate Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2023 | 50,000 | 61,808 (0%) | 0% | - | Common Stock | |
| B. Edgar Cale | GC & Corporate Secretary | Sale of securities on an exchange or to another person at price $ 0.91 per share. | 31 Dec 2023 | 15,813 | 45,995 (0%) | 0% | 0.9 | 14,390 | Common Stock |
| Mark Forman S. | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 0.91 per share. | 31 Dec 2023 | 15,813 | 45,269 (0%) | 0% | 0.9 | 14,390 | Common Stock |
| Forman Mark S. | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2023 | 50,000 | 61,082 (0%) | 0% | - | Common Stock | |
| Edgar Cale B. | GC & Corporate Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2023 | 50,000 | 0 | - | - | Restricted Stock Unit | |
| Kathleen Borthwick | SVP, Interim CFO | Sale of securities on an exchange or to another person at price $ 0.91 per share. | 31 Dec 2023 | 10,672 | 25,936 (0%) | 0% | 0.9 | 9,712 | Common Stock |
| Simona King | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jul 2023 | 31,250 | 35,447 (0%) | 0% | 0 | Common Stock | |
| Simona King | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jul 2023 | 31,250 | 0 | - | - | Restricted Stock Units | |
| Simona King | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.88 per share. | 28 Jul 2023 | 11,453 | 23,994 (0%) | 0% | 0.9 | 10,079 | Common Stock |
| Kathleen Borthwick | SVP, Interim CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2023 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Dolan Sondhi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jul 2023 | 48,000 | 48,000 | - | - | Director Stock Option (right to buy) | |
| Alex Fotopoulos | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 0.93 per share. | 15 Jun 2023 | 4,052 | 28,693 (0%) | 0% | 0.9 | 3,778 | Common Stock |
| Alex Fotopoulos | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2023 | 12,500 | 25,000 | - | - | Restricted Stock Units | |
| Alex Fotopoulos | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2023 | 12,500 | 32,745 (0%) | 0% | 0 | Common Stock | |
| Maxine Gowen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Michael E. Kamarck | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 21,567 | 21,567 | - | - | Director Stock Option (Right to Buy) | |
| Saqib Islam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Athena Countouriotis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Thomas F. Woiwode | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Sandip S. Kapadia | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Derrell D. Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Simona King | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Apr 2023 | 6,250 | 18,750 | - | - | Restricted Stock Units | |
| Simona King | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.05 per share. | 18 Apr 2023 | 2,053 | 2,053 (0%) | 0% | 1.1 | 2,156 | Common Stock |
| Simona King | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Apr 2023 | 6,250 | 6,250 (0%) | 0% | 0 | Common Stock | |
| Alex Fotopoulos | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Edgar B. Cale | GC & Corporate Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| Simona King | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 140,000 | 140,000 | - | - | Employee Stock Option (right to buy) | |
| Mark S. Forman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 175,000 | 175,000 | - | - | Employee Stock Option (right to buy) | |
| William Chou | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 608,615 | 608,615 | - | - | Employee Stock Option (right to buy) | |
| Sandip S. Kapadia | Director | Sale of securities on an exchange or to another person at price $ 1.19 per share. | 01 Dec 2022 | 5,000 | 0 (0%) | 0% | 1.2 | 5,965 | Common Stock |
| Alex Fotopoulos | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Nov 2022 | 12,500 | 23,965 (0%) | 0% | 0 | Common Stock | |
| Alex Fotopoulos | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Nov 2022 | 12,500 | 37,500 | - | - | Restricted Stock Units | |
| Alex Fotopoulos | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 1.33 per share. | 22 Nov 2022 | 3,720 | 20,245 (0%) | 0% | 1.3 | 4,948 | Common Stock |
| Alex Fotopoulos | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Nov 2022 | 50,000 | 50,000 | - | - | Restricted Stock Unit | |
| Edgar B. Cale | GC & Corporate Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Nov 2022 | 50,000 | 50,000 | - | - | Restricted Stock Unit | |
| Simona King | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Nov 2022 | 50,000 | 50,000 | - | - | Restricted Stock Unit | |
| Mark S. Forman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Nov 2022 | 50,000 | 50,000 | - | - | Restricted Stock Unit | |
| William Chou | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 885,000 | 885,000 | - | - | Employee Stock Option (right to buy) | |
| Monika Toernsen | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.51 per share. | 15 Sep 2022 | 1,681 | 3,319 (0%) | 0% | 1.5 | 2,539 | Common Stock |
| Monika Toernsen | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2022 | 5,000 | 15,000 | - | - | Restricted Stock Unit | |
| Monika Toernsen | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2022 | 5,000 | 5,000 (0%) | 0% | - | Common Stock | |
| Michael E. Kamarck | Director | 05 Jul 2022 | 48,000 | 48,000 | - | - | Stock Option (right to buy) | ||
| Alex Fotopoulos | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2022 | 200,000 | 200,000 | - | - | Employee Stock Option (right to buy) | |
| Edgar B. Cale | Interim CEO, GC & Corp. Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2022 | 106,000 | 106,000 | - | - | Employee Stock Option (right to buy) | |
| Monika Toernsen | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2022 | 101,000 | 101,000 | - | - | Employee Stock Option (right to buy) | |
| Simona King | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2022 | 159,000 | 159,000 | - | - | Employee Stock Option (right to buy) | |
| Mark S. Forman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2022 | 136,000 | 136,000 | - | - | Employee Stock Option (right to buy) | |
| Maxine Gowen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Edgar B. Cale | Interim CEO, GC & Corp. Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Bruce Goldsmith | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Maxine Gowen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Saqib Islam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Athena Countouriotis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Thomas Woiwode | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Sandip S. Kapadia | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Derrell Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 24,000 | 24,000 | - | - | Director Stock Option (Right to Buy) | |
| Simona King | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Apr 2022 | 25,000 | 25,000 | - | - | Restricted Stock Unit | |
| Mark S. Forman | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Apr 2022 | 136,000 | 136,000 | - | - | Employee Stock Options (right to buy) | |
| Bruce Goldsmith | Director, CEO and President | Purchase of securities on an exchange or from another person at price $ 3.15 per share. | 21 Mar 2022 | 10,000 | 15,983 (0%) | 0% | 3.2 | 31,500 | Common Stock |
| Eliseo O. Salinas | Chief Res. & Develop Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 157,500 | 157,500 | - | - | Stock Option (right to buy) | |
| Bruce Goldsmith | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 400,000 | 400,000 | - | - | Stock Option (right to buy) | |
| Alex Fotopoulos | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 163,900 | 163,900 | - | - | Stock Option (right to buy) | |
| Edgar B. Cale | GC and Corporate Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 106,000 | 106,000 | - | - | Stock Option (right to buy) | |
| Monika Toernsen | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 101,000 | 101,000 | - | - | Stock Option (right to buy) | |
| Simona King | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 159,000 | 159,000 | - | - | Stock Option (right to buy) | |
| M. Jill Quigley | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2021 | 60,782 | 27,626 | - | - | Employee Stock Option (right to buy) | |
| Jill Quigley M. | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.23 per share. | 08 Dec 2021 | 71,975 | 368,754 (0%) | 0% | 0.2 | 16,554 | Common Stock |
| M. Jill Quigley | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2021 | 11,193 | 3,729 | - | - | Employee Stock Option (right to buy) | |
| Simona King | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Aug 2021 | 360,000 | 360,000 | - | - | Employee Stock Option (Right to Buy) | |
| S. Mark Forman | CHIEF MEDICAL OFFICER | Sale of securities on an exchange or to another person at price $ 0.97 per share. | 16 Aug 2021 | 1,638 | 48,631 (0%) | 0% | 1.0 | 1,589 | Common Stock |
| S. Mark Forman | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2021 | 130,000 | 130,000 | - | - | Employee Stock Option (right to buy) | |
| S. Mark Forman | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2021 | 25,000 | 25,000 | - | - | Employee Stock Option (right to buy) | |
| Forman Mark S. | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Aug 2021 | 5,000 | 50,269 (0%) | 0% | - | Common Stock | |
| S. Forman Mark | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Aug 2021 | 5,000 | 10,000 | - | - | Restricted Stock Unit | |
| Mark S. Forman | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2021 | 15,000 | 15,000 | - | - | Restricted Stock Unit | |
| Monika Maria Toernsen | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2021 | 200,000 | 200,000 | - | - | Employee Stock Option (Right to Buy) | |
| Monika Maria Toernsen | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2021 | 20,000 | 20,000 | - | - | Restricted Stock Units | |
| Maxine Gowen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 4,542 | 4,542 | - | - | Director Stock Option (Right to Buy) | |
| Liam Ratcliffe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 16,918 | 16,918 | - | - | Director Stock Option (Right to Buy) | |
| Saqib Islam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 16,918 | 16,918 | - | - | Director Stock Option (Right to Buy) | |
| Athena Countouriotis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 16,918 | 16,918 | - | - | Director Stock Option (Right to Buy) | |
| Thomas Woiwode | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 16,918 | 16,918 | - | - | Director Stock Option (Right to Buy) | |
| Sandip S. Kapadia | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 16,918 | 16,918 | - | - | Director Stock Option (Right to Buy) | |
| Derrell Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 33,836 | 33,836 | - | - | Director Stock Option (Right to Buy) | |
| Richard S. Morris | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 13.82 per share. | 21 May 2021 | 2,171 | 5,454 (0%) | 0% | 13.8 | 30,000 | Common Stock |
| Bruce Goldsmith | Director, CEO and President | Purchase of securities on an exchange or from another person at price $ 13.12 per share. | 21 May 2021 | 2,000 | 5,983 (0%) | 0% | 13.1 | 26,230 | Common Stock |
| Alex Fotopoulos | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2021 | 50,000 | 50,000 | - | - | Restricted Stock Unit (RSU) | |
| Eliseo O. Salinas | Chief Res. & Develop Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2021 | 60,000 | 60,000 | - | - | Restricted Stock Unit (RSU) | |
| Eliseo O. Salinas | Chief Res. & Develop Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2021 | 40,000 | 40,000 | - | - | Restricted Stock Unit (RSU) | |
| Eliseo O. Salinas | Chief Res. & Develop Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2021 | 275,000 | 275,000 | - | - | Employee Stock Option (Right to buy) | |
| Gary Romano | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2021 | 10,000 | 300,821 | - | - | Employee Stock Option (right to buy) | |
| Gary Romano | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.07 per share. | 15 Mar 2021 | 10,000 | 10,000 (0%) | 0% | 8.1 | 80,700 | Common Stock |
| Gary Romano | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 20.95 per share. | 15 Mar 2021 | 8,383 | 1,617 (0%) | 0% | 21.0 | 175,662 | Common Stock |
| Gary Romano | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 21.86 per share. | 15 Mar 2021 | 1,617 | 0 (0%) | 0% | 21.9 | 35,350 | Common Stock |
| Maxine Gowen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2021 | 33,836 | 33,836 | - | - | Stock Option (right to buy) | |
| Richard S. Morris | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2021 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Bruce Goldsmith | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2021 | 262,000 | 262,000 | - | - | Stock Option (right to buy) | |
| Jill M. Quigley | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2021 | 105,000 | 105,000 | - | - | Stock Option (right to buy) | |
| Gary Romano | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2021 | 105,000 | 105,000 | - | - | Stock Option (right to buy) | |
| Alex Fotopoulos | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2021 | 105,000 | 105,000 | - | - | Stock Option (right to buy) | |
| Edgar B. Cale | GC and Corporate Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2021 | 170,997 | 170,997 | - | - | Stock Option (right to buy) | |
| Jill M. Quigley | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 30.01 per share. | 20 Jan 2021 | 1,300 | 295,284 (0%) | 0% | 30.0 | 39,011 | Common Stock |
| Jill M. Quigley | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 30.10 per share. | 14 Jan 2021 | 16,298 | 296,584 (0%) | 0% | 30.1 | 490,570 | Common Stock |
| Athena Countouriotis | None | Purchase of securities on an exchange or from another person at price $ 14.98 per share. | 24 Mar 2020 | 10,000 | 18,900 (0%) | 0% | 15.0 | 149,750 | Common Stock |
| Richard S. Morris | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 400 | 400 (0%) | 0% | 18 | 7,200 | Common Stock |
| Patrick J. Heron | Director, Ten Percent Owner | 03 Mar 2020 | 2,977,242 | 2,977,242 (6%) | 6% | 0 | Common Stock | ||
| Patrick J. Heron | Director, Ten Percent Owner | 03 Mar 2020 | 432,802 | 0 | - | - | Series B Preferred Stock | ||
| Patrick J. Heron | Director, Ten Percent Owner | 03 Mar 2020 | 1,049,175 | 0 | - | - | Series A-2 Preferred Stock | ||
| Patrick J. Heron | Director, Ten Percent Owner | 03 Mar 2020 | 2,977,242 | 0 | - | - | Series A-1 Preferred Stock | ||
| Patrick J. Heron | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 550,000 | 5,009,219 (11%) | 1% | 18 | 9,900,000 | Common Stock |
| Patrick J. Heron | Director, Ten Percent Owner | 03 Mar 2020 | 432,802 | 4,459,219 (10%) | 0% | 0 | Common Stock | ||
| Patrick J. Heron | Director, Ten Percent Owner | 03 Mar 2020 | 1,049,175 | 4,026,417 (9%) | 2% | 0 | Common Stock | ||
| Bruce Goldsmith | Director, CEO and President | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 1,100 | 1,100 (0%) | 0% | 18 | 19,800 | Common Stock |
| Liam Ratcliffe | None | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 550,000 | 2,616,630 (5%) | 1% | 18 | 9,900,000 | Common Stock |
| Liam Ratcliffe | None | 03 Mar 2020 | 2,066,630 | 0 | - | - | Series B Preferred Stock | ||
| Liam Ratcliffe | None | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 2,800 | 2,800 (0%) | 0% | 18 | 50,400 | Common Stock |
| Liam Ratcliffe | None | 03 Mar 2020 | 2,066,630 | 2,066,630 (4%) | 4% | 0 | Common Stock | ||
| Saqib Islam | None | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 5,000 | 5,000 (0%) | 0% | 18 | 90,000 | Common Stock |
| Athena Countouriotis | None | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 8,900 | 8,900 (0%) | 0% | 18 | 160,200 | Common Stock |
| Thomas Woiwode | Director, Ten Percent Owner | 03 Mar 2020 | 2,977,242 | 0 | - | - | Series A-1 Preferred Stock | ||
| Thomas Woiwode | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 225,000 | 933,352 (2%) | 0% | 18 | 4,050,000 | Common Stock |
| Thomas Woiwode | Director, Ten Percent Owner | 03 Mar 2020 | 708,352 | 708,352 (1%) | 1% | 0 | Common Stock | ||
| Thomas Woiwode | Director, Ten Percent Owner | 03 Mar 2020 | 1,049,175 | 4,026,417 (9%) | 2% | 0 | Common Stock | ||
| Thomas Woiwode | Director, Ten Percent Owner | 03 Mar 2020 | 2,977,242 | 2,977,242 (6%) | 6% | 0 | Common Stock | ||
| Thomas Woiwode | Director, Ten Percent Owner | 03 Mar 2020 | 1,049,175 | 0 | - | - | Series A-2 Preferred Stock | ||
| Thomas Woiwode | Director, Ten Percent Owner | 03 Mar 2020 | 708,352 | 0 | - | - | Series B Preferred Stock | ||
| Sandip S. Kapadia | None | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 5,000 | 5,000 (0%) | 0% | 18 | 90,000 | Common Stock |
| Jill M. Quigley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 1,500 | 311,494 (0%) | 0% | 18 | 27,000 | Common Stock |
| Jill M. Quigley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 1,000 | 1,000 (0%) | 0% | 18 | 18,000 | Common Stock |
| Alex Fotopoulos | Chief Technical Officer | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 5,500 | 5,500 (0%) | 0% | 18 | 99,000 | Common Stock |
| Edgar B. Cale | GC and Corporate Secretary | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 03 Mar 2020 | 2,000 | 2,000 (0%) | 0% | 18 | 36,000 | Common Stock |
| Richard S. Morris | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 74,311 | 74,311 | - | - | Employee Stock Option (Right to Buy) | |
| Stephen P. Squinto | Director, Head of Research and Dev | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 33,836 | 33,836 | - | - | Director Stock Option (Right to Buy) | |
| Stephen P. Squinto | Director, Head of Research and Dev | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 185,776 | 185,776 | - | - | Employee Stock Option (Right to Buy) | |
| Patrick J. Heron | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 33,836 | 33,836 | - | - | Director Stock Option (Right to Buy) | |
| Liam Ratcliffe | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 33,836 | 33,836 | - | - | Director Stock Option (Right to Buy) | |
| Saqib Islam | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 16,918 | 16,918 | - | - | Director Stock Option (Right to Buy) | |
| Athena Countouriotis | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 33,836 | 33,836 | - | - | Director Stock Option (Right to Buy) | |
| Thomas Woiwode | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 33,836 | 33,836 | - | - | Director Stock Option (Right to Buy) | |
| Sandip S. Kapadia | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 16,918 | 16,918 | - | - | Director Stock Option (Right to Buy) | |
| Jill M. Quigley | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 211,001 | 211,001 | - | - | Employee Stock Option (Right to Buy) | |
| Gary Romano | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 74,311 | 74,311 | - | - | Employee Stock Option (Right to Buy) | |
| Alex Fotopoulos | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 74,311 | 74,311 | - | - | Employee Stock Option (Right to Buy) | |
| Edgar B. Cale | GC and Corporate Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2020 | 99,731 | 99,731 | - | - | Employee Stock Option (Right to Buy) |