- XNAS Volume
XNAS 24 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Daniel L. Kisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,200 | 2,200 | - | - | Stock Options | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 3,300 | 3,300 | - | - | Stock Options | |
| Rosemary Mazanet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,200 | 2,200 | - | - | Stock Options | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,200 | 2,200 | - | - | Stock Options | |
| Charles P. Theuer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,200 | 2,200 | - | - | Stock Options | |
| Robert J. Wills | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,200 | 2,200 | - | - | Stock Options | |
| Jill DeSimone | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 2,200 | 2,200 | - | - | Stock Options | |
| Robert J. Wills | Director | Purchase of securities on an exchange or from another person at price $ 8.96 per share. | 08 Apr 2024 | 3,086 | 10,000 (0%) | 0% | 9.0 | 27,655 | Common Stock |
| Robert J. Wills | Director | Purchase of securities on an exchange or from another person at price $ 8.48 per share. | 28 Mar 2024 | 6,914 | 6,914 (0%) | 0% | 8.5 | 58,602 | Common Stock |
| David F. Hale | Director | Purchase of securities on an exchange or from another person at price $ 9.04 per share. | 23 Feb 2024 | 266 | 29,673 (0%) | 0% | 9.0 | 2,405 | Common Stock |
| Wills Robert J. | Director | Sale of securities on an exchange or to another person at price $ 9.04 per share. | 23 Feb 2024 | 980 | 0 (0%) | 0% | 9.0 | 8,859 | Common Stock |
| David Hale F. | Director | Purchase of securities on an exchange or from another person at price $ 9.04 per share. | 23 Feb 2024 | 714 | 714 (0%) | 0% | 9.0 | 6,455 | Common Stock |
| G. Vincent Richard | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2024 | 14,200 | 14,200 | - | - | Stock Option | |
| Krishnan Rajesh | CTO/CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2024 | 17,700 | 17,700 | - | - | Stock Option | |
| Yazji Salim | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2024 | 14,200 | 14,200 | - | - | Stock Option | |
| Leavitt C. Chase | General Counsel/Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2024 | 14,200 | 14,200 | - | - | Stock Option | |
| Chase C. Leavitt | General Counsel/Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.50 per share. | 03 Jan 2024 | 11,838 | 84,758 (0%) | 0% | 0.5 | 5,873 | Common Stock |
| Vincent G. Richard | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.50 per share. | 03 Jan 2024 | 8,868 | 140,922 (0%) | 0% | 0.5 | 4,399 | Common Stock |
| Rajesh Krishnan | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.50 per share. | 03 Jan 2024 | 11,838 | 44,019 (0%) | 0% | 0.5 | 5,873 | Common Stock |
| Salim Yazji | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.50 per share. | 03 Jan 2024 | 19,742 | 128,635 (0%) | 0% | 0.5 | 9,794 | Common Stock |
| Rajesh Krishnan | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.36 per share. | 03 Jul 2023 | 10,897 | 55,857 (0%) | 0% | 0.4 | 3,923 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.36 per share. | 03 Jul 2023 | 7,069 | 149,790 (0%) | 0% | 0.4 | 2,545 | Common Stock |
| Chase C. Leavitt | General Counsel/Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.36 per share. | 03 Jul 2023 | 10,305 | 96,596 (0%) | 0% | 0.4 | 3,710 | Common Stock |
| Salim Yazji | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.36 per share. | 03 Jul 2023 | 16,299 | 148,377 (0%) | 0% | 0.4 | 5,868 | Common Stock |
| Daniel L. Kisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 25,000 | 25,000 | - | - | Stock Options | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 37,500 | 37,500 | - | - | Stock Options | |
| Rosemary Mazanet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 25,000 | 25,000 | - | - | Stock Options | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 25,000 | 25,000 | - | - | Stock Options | |
| Charles P. Theuer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 25,000 | 25,000 | - | - | Stock Options | |
| Robert J. Wills | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 25,000 | 25,000 | - | - | Stock Options | |
| Xin Nakanishi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 25,000 | 25,000 | - | - | Stock Options | |
| Jill DeSimone | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2023 | 25,000 | 25,000 | - | - | Stock Options | |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.30 per share. | 13 Apr 2023 | 30,000 | 156,859 (1%) | 0% | 0.3 | 8,961 | Common Stock |
| Chase C. Leavitt | General Counsel/Secretary | Purchase of securities on an exchange or from another person at price $ 0.29 per share. | 12 Apr 2023 | 10,000 | 106,901 (0%) | 0% | 0.3 | 2,900 | Common Stock |
| Chase C. Leavitt | General Counsel/Secretary | Purchase of securities on an exchange or from another person at price $ 0.29 per share. | 12 Apr 2023 | 15,000 | 96,901 (0%) | 0% | 0.3 | 4,350 | Common Stock |
| Salim Yazji | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.28 per share. | 12 Apr 2023 | 10,000 | 149,676 (0%) | 0% | 0.3 | 2,850 | Common Stock |
| Salim Yazji | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.28 per share. | 12 Apr 2023 | 10,000 | 159,676 (1%) | 0% | 0.3 | 2,850 | Common Stock |
| Salim Yazji | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.30 per share. | 12 Apr 2023 | 5,000 | 164,676 (1%) | 0% | 0.3 | 1,500 | Common Stock |
| Rajesh Krishnan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2023 | 220,000 | 220,000 | - | - | Stock Option | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2023 | 210,000 | 210,000 | - | - | Stock Option | |
| Chase C. Leavitt | General Counsel/Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2023 | 210,000 | 210,000 | - | - | Stock Option | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2023 | 210,000 | 210,000 | - | - | Stock Option | |
| Salim Yazji | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2023 | 210,000 | 210,000 | - | - | Stock Option | |
| Jill DeSimone | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2023 | 50,000 | 50,000 | - | - | Stock Option | |
| Rajesh Krishnan | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.02 per share. | 03 Jan 2023 | 6,238 | 66,754 (0%) | 0% | 1.0 | 6,363 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.02 per share. | 03 Jan 2023 | 4,428 | 126,859 (0%) | 0% | 1.0 | 4,517 | Common Stock |
| Chase C. Leavitt | General Counsel/Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.02 per share. | 03 Jan 2023 | 6,091 | 81,901 (0%) | 0% | 1.0 | 6,213 | Common Stock |
| Gunnar F. Kaufmann | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.02 per share. | 03 Jan 2023 | 6,266 | 66,726 (0%) | 0% | 1.0 | 6,391 | Common Stock |
| Salim Yazji | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.02 per share. | 03 Jan 2023 | 9,961 | 139,676 (0%) | 0% | 1.0 | 10,160 | Common Stock |
| Rajesh Krishnan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 43,125 | 72,992 (0%) | 0% | 0 | Common Stock | |
| Rajesh Krishnan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 28,750 | 28,750 | - | - | Stock Option | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 43,125 | 131,287 (0%) | 0% | 0 | Common Stock | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 28,750 | 28,750 | - | - | Stock Option | |
| Chase C. Leavitt | General Counsel/Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 28,750 | 28,750 | - | - | Stock Option | |
| Chase C. Leavitt | General Counsel/Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 43,125 | 87,992 (0%) | 0% | 0 | Common Stock | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 43,125 | 72,992 (0%) | 0% | 0 | Common Stock | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 28,750 | 28,750 | - | - | Stock Option | |
| Salim Yazji | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 82,500 | 149,637 (0%) | 0% | 0 | Common Stock | |
| Salim Yazji | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 55,000 | 55,000 | - | - | Stock Option | |
| Daniel L. Kisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 25,000 | 25,000 | - | - | Stock Options | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 37,500 | 37,500 | - | - | Stock Options | |
| Rosemary Mazanet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 25,000 | 25,000 | - | - | Stock Options | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 25,000 | 25,000 | - | - | Stock Options | |
| Charles P. Theuer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 25,000 | 25,000 | - | - | Stock Options | |
| Robert J. Wills | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 25,000 | 25,000 | - | - | Stock Options | |
| Xin Nakanishi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 25,000 | 25,000 | - | - | Stock Options | |
| Jinzhu Chen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 25,000 | 25,000 | - | - | Stock Options | |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.49 per share. | 24 Mar 2022 | 2,136 | 85,662 (0%) | 0% | 1.5 | 3,182 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.33 per share. | 24 Mar 2022 | 3 | 83,165 (0%) | 0% | 1.3 | 4 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.45 per share. | 24 Mar 2022 | 356 | 83,521 (0%) | 0% | 1.4 | 516 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.40 per share. | 24 Mar 2022 | 5 | 83,526 (0%) | 0% | 1.4 | 7 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.40 per share. | 24 Mar 2022 | 2,500 | 88,162 (0%) | 0% | 1.4 | 3,500 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.65 per share. | 27 Jan 2022 | 2,500 | 83,162 (0%) | 0% | 1.7 | 4,125 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.70 per share. | 27 Jan 2022 | 5,000 | 80,662 (0%) | 0% | 1.7 | 8,500 | Common Stock |
| Richard G. Vincent | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.80 per share. | 27 Jan 2022 | 5,000 | 75,662 (0%) | 0% | 1.8 | 9,000 | Common Stock |
| Chase C. Leavitt | General Counsel/Secretary | Purchase of securities on an exchange or from another person at price $ 1.63 per share. | 27 Jan 2022 | 5,000 | 44,867 (0%) | 0% | 1.6 | 8,150 | Common Stock |
| Chase C. Leavitt | General Counsel/Secretary | Purchase of securities on an exchange or from another person at price $ 1.78 per share. | 27 Jan 2022 | 8,500 | 39,867 (0%) | 0% | 1.8 | 15,130 | Common Stock |
| Salim Yazji | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 1.69 per share. | 27 Jan 2022 | 10,000 | 67,137 (0%) | 0% | 1.7 | 16,900 | Common Stock |
| Rajesh Krishnan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jan 2022 | 177,050 | 177,050 | - | - | Stock Option | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jan 2022 | 109,579 | 109,579 | - | - | Stock Option | |
| Chase C. Leavitt | General Counsel/Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jan 2022 | 55,519 | 55,519 | - | - | Stock Option | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jan 2022 | 162,457 | 162,457 | - | - | Stock Option | |
| Salim Yazji | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jan 2022 | 92,075 | 92,075 | - | - | Stock Option | |
| Rajesh Krishnan | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 29,867 | 29,867 (0%) | 0% | 0 | Common Stock | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 29,867 | 70,662 (0%) | 0% | 0 | Common Stock | |
| Chase C. Leavitt | General Counsel/Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 29,867 | 31,367 (0%) | 0% | 0 | Common Stock | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 29,867 | 29,867 (0%) | 0% | 0 | Common Stock | |
| Salim Yazji | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2022 | 57,137 | 57,137 (0%) | 0% | 0 | Common Stock | |
| Daniel L. Kisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 25,000 | 25,000 | - | - | Stock Options | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 37,500 | 37,500 | - | - | Stock Options | |
| Rosemary Mazanet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 25,000 | 25,000 | - | - | Stock Options | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 25,000 | 25,000 | - | - | Stock Options | |
| Charles P. Theuer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 25,000 | 25,000 | - | - | Stock Options | |
| Robert J. Wills | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 25,000 | 25,000 | - | - | Stock Options | |
| Xin Nakanishi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 25,000 | 25,000 | - | - | Stock Options | |
| Jinzhu Chen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2021 | 50,000 | 50,000 | - | - | Stock Options | |
| Rosemary Mazanet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2021 | 20,000 | 20,000 | - | - | Stock Options | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2021 | 280,000 | 280,000 | - | - | Stock Option | |
| Igor Bilinsky | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2021 | 130,000 | 130,000 | - | - | Stock Option | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2021 | 253,000 | 253,000 | - | - | Stock Option | |
| Rosemary Mazanet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2021 | 30,000 | 30,000 | - | - | Stock Options | |
| Daniel L. Kisner | Director | Purchase of securities on an exchange or from another person at price $ 2.38 per share. | 21 Jul 2020 | 10,000 | 10,000 (0%) | 0% | 2.4 | 23,825 | Common Stock |
| Daniel L. Kisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jul 2020 | 5,000 | 5,000 | - | - | Warrants | |
| Hazel M. Aker | Legal Counsel | Purchase of securities on an exchange or from another person at price $ 2.38 per share. | 21 Jul 2020 | 41,972 | 46,987 (0%) | 0% | 2.4 | 99,998 | Common Stock |
| Hazel M. Aker | Legal Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jul 2020 | 20,986 | 20,986 | - | - | Warrants | |
| Daniel L. Kisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 15,000 | 30,000 | - | - | Stock Options | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 22,500 | 22,500 | - | - | Stock Option | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option | |
| Charles P. Theuer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option | |
| Robert J. Wills | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option | |
| Robert J. Wills | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 15,000 | 15,000 | - | - | Stock Options | |
| Xin Nakanishi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option | |
| Man Cho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option | |
| David F. Hale | Director | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 May 2020 | 8,706 | 8,706 | - | - | Warrants | |
| David F. Hale | Director | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 May 2020 | 17,412 | 716,818 (4%) | 0% | - | Common Stock | |
| Hazel M. Aker | Legal Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 11,080 | 11,080 | - | - | Stock Option | |
| Hazel M. Aker | Legal Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 11,080 | 11,080 | - | - | Stock Option | |
| Hazel M. Aker | Legal Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 11,080 | 11,080 | - | - | Stock Option | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 35,120 | 35,120 | - | - | Common Stock | |
| Igor Bilinsky | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 12,690 | 12,690 | - | - | Stock Option | |
| Frank J. Hsu | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 16,280 | 16,280 | - | - | Stock Option | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 14,260 | 14,260 | - | - | Stock Option | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2020 | 14,260 | 14,260 | - | - | Stock Option | |
| Man Cho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Daniel L. Kisner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 40,000 | 40,000 | - | - | Stock Option | |
| Hazel M. Aker | Legal Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 150,000 | 150,000 | - | - | Stock Option | |
| Hazel M. Aker | Legal Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 150,000 | 150,000 | - | - | Stock Option | |
| Hazel M. Aker | Legal Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 150,000 | 150,000 | - | - | Stock Option | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 75,000 | 75,000 | - | - | Stock Option | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 75,000 | 75,000 | - | - | Stock Option | |
| Michael G Carter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Charles P. Theuer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Robert J. Wills | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 30,000 | 30,000 | - | - | Stock Options | |
| Yanjun Liu | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Xin Nakanishi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Igor Bilinsky | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2019 | 150,000 | 150,000 | - | - | Stock Option | |
| Gunnar F. Kaufmann | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Sep 2019 | 150,000 | 150,000 | - | - | Stock Option | |
| Frank J. Hsu | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Aug 2019 | 150,000 | 150,000 | - | - | Stock Option | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 3,292 | 3,292 | - | - | Warrants | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 699,406 | 699,406 (4%) | 4% | - | Common Stock | |
| David F. Hale | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 18,346 | 18,346 (0%) | 0% | - | Common Stock | |
| Hazel M. Aker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 140 | 140 | - | - | Warrants | |
| Hazel M. Aker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 4,284 | 4,284 (0%) | 0% | - | Common Stock | |
| Hazel M. Aker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 5,015 | 5,015 (0%) | 0% | - | Common Stock | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 10,030 | 10,030 (0%) | 0% | - | Common Stock | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 16,144 | 16,144 (0%) | 0% | - | Common Stock | |
| William R. Larue | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 281 | 281 | - | - | Warrants | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 73,385 | 73,385 | - | - | Stock Options | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 281 | 281 | - | - | Warrants | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 42,628 | 40,794 (0%) | 0% | - | Common Stock | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 1,834 | 1,834 (0%) | 0% | - | Common Stock | |
| Richard G. Vincent | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 4,526 | 4,526 (0%) | 0% | - | Common Stock | |
| Charles P. Theuer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2019 | 14,677 | 14,677 (0%) | 0% | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.86 per share. | 02 Jan 2019 | 18,168 | 4,207,367 (27%) | 0% | 0.9 | 15,625 | Common Stock |
| Garry A. Neil | Director | Grant, award, or other acquisition of securities at price $ 0.86 per share. | 02 Jan 2019 | 14,534 | 36,759 (0%) | 0% | 0.9 | 12,500 | Common Stock |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 1.50 per share. | 01 Oct 2018 | 8,916 | 44,105 (0%) | 0% | 1.5 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 1.50 per share. | 01 Oct 2018 | 10,416 | 1,939,199 (8%) | 0% | 1.5 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 1.50 per share. | 01 Oct 2018 | 8,333 | 22,224 (0%) | 0% | 1.5 | 12,500 | Common Stock |
| Diane C. Young | VP, Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 14.92 per share. | 13 Jul 2018 | 2,014 | 47,985 (0%) | 0% | 14.9 | 30,049 | Common Stock |
| Diane C. Young | VP, Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 14.70 per share. | 13 Jul 2018 | 2,049 | 45,936 (0%) | 0% | 14.7 | 30,120 | Common Stock |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 15.48 per share. | 02 Jul 2018 | 864 | 35,188 (0%) | 0% | 15.5 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 15.47 per share. | 02 Jul 2018 | 1,010 | 1,928,782 (8%) | 0% | 15.5 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 15.47 per share. | 02 Jul 2018 | 808 | 13,890 (0%) | 0% | 15.5 | 12,500 | Common Stock |
| Robert J. Wills | Director, Executive Chairman | Purchase of securities on an exchange or from another person at price $ 16.75 per share. | 26 Jun 2018 | 5,000 | 137,344 (0%) | 0% | 16.8 | 83,750 | Common Stock |
| Henry P. Doggrell | VP, Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 19.01 per share. | 20 Jun 2018 | 7,351 | 43,630 (0%) | 0% | 19.0 | 139,708 | Common Stock |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Sale of securities on an exchange or to another person at price $ 19.01 per share. | 20 Jun 2018 | 9,279 | 19,453 (0%) | 0% | 19.0 | 176,350 | Common Stock |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2018 | 7,500 | 7,500 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2018 | 7,500 | 7,500 | - | - | Director Stock Option (Right to Buy) | |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2018 | 7,500 | 7,500 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 17.48 per share. | 02 Apr 2018 | 765 | 34,323 (0%) | 0% | 17.5 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 17.48 per share. | 02 Apr 2018 | 894 | 1,927,772 (8%) | 0% | 17.5 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 17.48 per share. | 02 Apr 2018 | 715 | 13,082 (0%) | 0% | 17.5 | 12,500 | Common Stock |
| Henry P. Doggrell | VP, Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 12.02 per share. | 05 Jan 2018 | 1,142 | 54,804 (0%) | 0% | 12.0 | 13,727 | Common Stock |
| Henry P. Doggrell | VP, Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 11.13 per share. | 05 Jan 2018 | 3,823 | 50,981 (0%) | 0% | 11.1 | 42,550 | Common Stock |
| Marc S. Hanover | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 11.13 per share. | 05 Jan 2018 | 5,628 | 124,362 (0%) | 0% | 11.1 | 62,640 | Common Stock |
| Marc S. Hanover | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 12.02 per share. | 05 Jan 2018 | 1,681 | 129,990 (0%) | 0% | 12.0 | 20,206 | Common Stock |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Sale of securities on an exchange or to another person at price $ 11.13 per share. | 05 Jan 2018 | 2,379 | 28,732 (0%) | 0% | 11.1 | 26,478 | Common Stock |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Sale of securities on an exchange or to another person at price $ 12.02 per share. | 05 Jan 2018 | 711 | 31,111 (0%) | 0% | 12.0 | 8,546 | Common Stock |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 11.46 per share. | 02 Jan 2018 | 1,167 | 33,558 (0%) | 0% | 11.5 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 11.46 per share. | 02 Jan 2018 | 1,363 | 1,734,893 (8%) | 0% | 11.5 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 11.47 per share. | 02 Jan 2018 | 1,090 | 12,367 (0%) | 0% | 11.5 | 12,500 | Common Stock |
| Henry P. Doggrell | VP, Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2018 | 45,000 | 45,000 | - | - | Employee Stock Option (Right to Buy) | |
| Henry P. Doggrell | VP, Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.71 per share. | 01 Jan 2018 | 4,345 | 55,946 (0%) | 0% | 12.7 | 55,225 | Common Stock |
| Marc S. Hanover | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.71 per share. | 01 Jan 2018 | 6,397 | 131,671 (0%) | 0% | 12.7 | 81,306 | Common Stock |
| Marc S. Hanover | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2018 | 65,000 | 65,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.71 per share. | 01 Jan 2018 | 2,704 | 31,822 (0%) | 0% | 12.7 | 34,368 | Common Stock |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2018 | 45,000 | 45,000 | - | - | Employee Stock Option (Right to Buy) | |
| Robert J. Wills | Director, Executive Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2018 | 65,000 | 65,000 | - | - | Employee Stock Option (Right to Buy) | |
| Diane C. Young | VP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2018 | 25,000 | 25,000 | - | - | Employee Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 7.94 per share. | 02 Oct 2017 | 1,684 | 32,391 (0%) | 0% | 7.9 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 7.94 per share. | 02 Oct 2017 | 1,967 | 3,983,529 (18%) | 0% | 7.9 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 7.94 per share. | 02 Oct 2017 | 1,574 | 11,276 (0%) | 0% | 7.9 | 12,500 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Sep 2017 | 678,349 | 678,349 | - | - | Common Stock Warrants (right to buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Sep 2017 | 1,130,582 | 3,981,561 (18%) | 5% | 0 | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 5.26 per share. | 03 Jul 2017 | 2,542 | 30,706 (0%) | 0% | 5.3 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 5.26 per share. | 03 Jul 2017 | 2,970 | 2,828,264 (17%) | 0% | 5.3 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 5.26 per share. | 03 Jul 2017 | 2,376 | 9,702 (0%) | 0% | 5.3 | 12,500 | Common Stock |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2017 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2017 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2017 | 11,250 | 11,250 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 4.90 per share. | 03 Apr 2017 | 2,729 | 28,164 (0%) | 0% | 4.9 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 4.90 per share. | 03 Apr 2017 | 3,188 | 2,075,287 (12%) | 0% | 4.9 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 4.90 per share. | 03 Apr 2017 | 2,551 | 7,325 (0%) | 0% | 4.9 | 12,500 | Common Stock |
| Henry P. Doggrell | VP, Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2017 | 80,000 | 80,000 | - | - | Employee Stock Option (Right to Buy) | |
| Marc S. Hanover | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2017 | 95,000 | 95,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2017 | 70,000 | 70,000 | - | - | Employee Stock Option (Right to Buy) | |
| Robert J. Wills | Director, Executive Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2017 | 95,000 | 95,000 | - | - | Employee Stock Option (Right to Buy) | |
| Diane C. Young | VP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2017 | 50,000 | 50,000 | - | - | Employee Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 5.21 per share. | 03 Jan 2017 | 2,567 | 25,434 (0%) | 0% | 5.2 | 13,375 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 5.21 per share. | 03 Jan 2017 | 2,999 | 4,322,098 (27%) | 0% | 5.2 | 15,625 | Common Stock |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 5.21 per share. | 03 Jan 2017 | 2,399 | 4,774 (0%) | 0% | 5.2 | 12,500 | Common Stock |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 7,716,049 | 43,191,009 | - | - | Common Stock | |
| Marc S. Hanover | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 123,456 | 1,380,680 | - | - | Common Stock | |
| Robert J. Wills | Director, Executive Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 123,456 | 1,323,456 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2016 | 20,559 | 35,474,960 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2016 | 17,598 | 228,672 | - | - | Common Stock | |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Oct 2016 | 16,447 | 23,757 | - | - | Common Stock | |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Sep 2016 | 7,309 | 7,309 | - | - | Common Stock | |
| Garry A. Neil | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Aug 2016 | 100,000 | 100,000 | - | - | Director Stock Option (Right to Buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2016 | 28,409 | 33,354,225 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2016 | 24,318 | 211,073 | - | - | Common Stock | |
| Robert J. Wills | Director, Executive Chairman | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 16 Jun 2016 | 100,000 | 1,200,000 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2016 | 50,000 | 50,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2016 | 50,000 | 50,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2016 | 50,000 | 50,000 | - | - | Director Stock Option (Right to Buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2016 | 27,901 | 29,325,855 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2016 | 23,883 | 186,755 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Mar 2016 | 44,000 | 183,767 | - | - | Common Stock | |
| Marc S. Hanover | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 Jan 2016 | 4,000 | 1,257,224 | - | - | Common Stock | |
| Marc S. Hanover | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 25 Jan 2016 | 12,813 | 1,253,224 | - | - | Common Stock | |
| Marc S. Hanover | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 25,000 | 1,240,411 | - | - | Common Stock | |
| Marc S. Hanover | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 22,100 | 1,215,411 | - | - | Common Stock | |
| Marc S. Hanover | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 2,900 | 1,193,311 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 22,007 | 29,297,984 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 18,838 | 162,871 | - | - | Common Stock | |
| Henry P. Doggrell | VP, Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2016 | 250,000 | 250,000 | - | - | Employee Stock Option (Right to Buy) | |
| Marc S. Hanover | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2016 | 400,000 | 400,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2016 | 175,000 | 175,000 | - | - | Employee Stock Option (Right to Buy) | |
| Robert J. Wills | Director, Executive Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2016 | 400,000 | 400,000 | - | - | Employee Stock Option (Right to Buy) | |
| Diane C. Young | VP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2016 | 150,000 | 150,000 | - | - | Employee Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Dec 2015 | 100 | 139,767 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Dec 2015 | 600 | 139,667 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Dec 2015 | 1,307 | 139,067 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Dec 2015 | 39,900 | 137,760 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2015 | 19,500 | 29,275,977 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2015 | 16,500 | 144,033 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2015 | 9,685 | 28,183,805 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2015 | 8,195 | 127,533 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 May 2015 | 24,500 | 24,500 | - | - | Common Stock | |
| Robert J. Wills | Director, Executive Chairman | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 May 2015 | 9,700 | 63,560 | - | - | Common Stock | |
| Robert J. Wills | Director, Executive Chairman | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 May 2015 | 36,440 | 100,000 | - | - | Common Stock | |
| Robert J. Wills | Director, Executive Chairman | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 May 2015 | 3,860 | 53,860 | - | - | Common Stock | |
| Henry P. Doggrell | VP, Chief Legal Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 08 May 2015 | 25,477 | 25,477 | - | - | Common Stock | |
| Robert J. Wills | Director, Executive Chairman | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 08 May 2015 | 50,000 | 50,000 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2015 | 100,000 | 100,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2015 | 100,000 | 100,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2015 | 100,000 | 100,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Apr 2015 | 10,000 | 97,860 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Apr 2015 | 3,952 | 80,204 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Apr 2015 | 7,656 | 87,860 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Apr 2015 | 3,300 | 76,252 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Apr 2015 | 16,400 | 72,952 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2015 | 22,159 | 39,674,119 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2015 | 18,750 | 119,338 | - | - | Common Stock | |
| Robert J. Wills | Director, Executive Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2015 | 1,000,000 | 1,000,000 | - | - | Common Stock | |
| Henry P. Doggrell | VP, Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2015 | 500,000 | 602,913 | - | - | Common Stock | |
| Marc S. Hanover | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2015 | 750,000 | 1,190,411 | - | - | Common Stock | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2015 | 300,000 | 345,263 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 18,166 | 39,552,566 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 14,833 | 100,588 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 8,583 | 48,468 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2014 | 24,545,455 | 39,379,660 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2014 | 24,545,455 | 24,545,455 | - | - | Common Stock Warrants (right to buy) | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2014 | 227,273 | 440,411 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2014 | 227,273 | 227,273 | - | - | Common Stock Warrants (right to buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2014 | 18,664 | 14,834,205 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2014 | 15,239 | 85,754 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2014 | 8,818 | 39,885 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 Sep 2014 | 5,000 | 213,138 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Sep 2014 | 10,000 | 208,138 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Aug 2014 | 10,000 | 188,138 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Aug 2014 | 10,000 | 198,138 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Aug 2014 | 1,652 | 169,790 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Aug 2014 | 8,348 | 178,138 | - | - | Common Stock | |
| Henry P. Doggrell | VP, Chief Legal Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 08 Aug 2014 | 10,000 | 102,913 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Aug 2014 | 20,000 | 158,138 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Aug 2014 | 30,000 | 138,138 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Aug 2014 | 10,000 | 168,138 | - | - | Common Stock | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Aug 2014 | 10,000 | 45,263 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2014 | 9,802 | 18,215,541 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2014 | 8,003 | 70,515 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2014 | 4,631 | 31,066 | - | - | Common Stock | |
| James T. Dalton | VP, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Jun 2014 | 72,883 | 0 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2014 | 250,000 | 250,000 | - | - | Employee Stock Option (Right to Buy) | |
| Henry P. Doggrell | VP, Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 01 Jun 2014 | 27,087 | 92,913 | - | - | Common Stock | |
| Henry P. Doggrell | VP, Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2014 | 200,000 | 200,000 | - | - | Employee Stock Option (Right to Buy) | |
| James T. Dalton | VP, Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 01 Jun 2014 | 27,117 | 72,883 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2014 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2014 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2014 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2014 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2014 | 150,000 | 150,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2014 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jason T. Shackelford | Prin Fin. & Acct. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 05 May 2014 | 14,737 | 35,263 | - | - | Common Stock | |
| Marc S. Hanover | Director, Interim CEO, President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Apr 2014 | 500,000 | 500,000 | - | - | Employee Stock Option (Right to Buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2014 | 8,733 | 18,205,739 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2014 | 7,131 | 62,511 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2014 | 4,126 | 26,435 | - | - | Common Stock | |
| Jack W Schuler | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2014 | 115,492 | 6,803,900 | - | - | Common Stock | |
| Jack W Schuler | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2014 | 638,639 | 6,165,261 | - | - | Common Stock | |
| Jack W Schuler | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2014 | 438,120 | 6,919,392 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Mar 2014 | 5,988,024 | 18,197,005 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Mar 2014 | 5,988,024 | 5,988,024 | - | - | Common Stock Warrants (right to buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2014 | 8,110 | 11,577,156 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2014 | 6,622 | 55,380 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2014 | 3,831 | 22,308 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2013 | 7,286 | 10,723,785 | - | - | Common Stock | |
| Henry P. Doggrell | VP, Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2013 | 100,000 | 100,000 | - | - | Nonstatutory Stock Option (Right to Buy) | |
| Henry P. Doggrell | VP, Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2013 | 100,000 | 120,000 | - | - | Common Stock | |
| James T. Dalton | VP, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2013 | 100,000 | 100,000 | - | - | Nonstatutory Stock Option (Right to Buy) | |
| James T. Dalton | VP, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2013 | 100,000 | 100,000 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2013 | 5,949 | 48,758 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2013 | 3,442 | 18,476 | - | - | Common Stock | |
| Jack W Schuler | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Aug 2013 | 93,777 | 7,357,512 | - | - | Common Stock | |
| Jack W Schuler | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Aug 2013 | 110,005 | 7,064,149 | - | - | Common Stock | |
| Jack W Schuler | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Aug 2013 | 199,586 | 7,263,735 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jul 2013 | 295,737 | 0 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jul 2013 | 98,579 | 508,904 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jul 2013 | 98,579 | 508,903 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jul 2013 | 98,579 | 508,903 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jul 2013 | 59,146 | 0 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jul 2013 | 59,146 | 203,791 | - | - | Common Stock | |
| Mark E. Mosteller | Vice President, CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jul 2013 | 17,000 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Mark E. Mosteller | Vice President, CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jul 2013 | 17,000 | 17,000 | - | - | Common Stock | |
| Mark E. Mosteller | Vice President, CFO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Jul 2013 | 11,505 | 5,495 | - | - | Common Stock | |
| Mark E. Mosteller | Vice President, CFO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Jul 2013 | 5,495 | 0 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2013 | 2,058 | 9,590,371 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2013 | 1,680 | 42,808 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2013 | 972 | 15,034 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2013 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2013 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2013 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2013 | 20,000 | 20,000 | - | - | Director Stock Option (Right to Buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2013 | 3,372 | 9,405,014 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2013 | 2,753 | 41,128 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2013 | 1,779 | 14,062 | - | - | Common Stock | |
| James T. Dalton | VP, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jan 2013 | 20,000 | 30,000 | - | - | Employee Stock Option (Right to Buy) | |
| James T. Dalton | VP, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jan 2013 | 20,000 | 20,000 | - | - | Common Stock | |
| James T. Dalton | VP, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Jan 2013 | 20,000 | 0 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 2,946 | 45,668 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 3,898 | 9,132,860 | - | - | Common Stock | |
| Henry P. Doggrell | Vice President and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 654 | 36,319 | - | - | Common Stock | |
| Marc S. Hanover | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 90,000 | 90,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mark E. Mosteller | Vice President and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 135,000 | 135,000 | - | - | Employee Stock Option (Right to Buy) | |
| James T. Dalton | VP, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 55,000 | 55,000 | - | - | Employee Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 3,125 | 38,374 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2013 | 1,592 | 12,282 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2012 | 1,801 | 142,721 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2012 | 1,801 | 9,957,409 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2012 | 2,210 | 35,664 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2012 | 1,801 | 35,249 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2012 | 1,173 | 10,690 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Aug 2012 | 10,000 | 40,550 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 12 Jul 2012 | 38,563 | 1,954,423 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 12 Jul 2012 | 61,437 | 1,892,986 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 12 Jul 2012 | 25,035 | 1,867,951 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2012 | 2,556 | 140,920 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2012 | 2,343 | 9,581,736 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2012 | 3,586 | 33,454 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2012 | 2,556 | 33,448 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2012 | 2,000 | 9,517 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2012 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2012 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2012 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2012 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2012 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Apr 2012 | 26,585 | 1,994,123 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Apr 2012 | 1,137 | 1,992,986 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 09 Apr 2012 | 38,923 | 2,025,208 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 09 Apr 2012 | 4,500 | 2,020,708 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2012 | 2,727 | 138,363 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2012 | 2,532 | 9,147,772 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2012 | 2,532 | 29,867 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2012 | 2,727 | 30,891 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2012 | 1,266 | 7,516 | - | - | Common Stock | |
| Jack W Schuler | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Mar 2012 | 796,923 | 6,954,144 | - | - | common stock | |
| Jack W Schuler | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Mar 2012 | 69,700 | 6,157,221 | - | - | common stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 2,455 | 135,636 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 2,455 | 10,145,240 | - | - | Common Stock | |
| Henry P. Doggrell | Vice President and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 2,455 | 27,334 | - | - | Common Stock | |
| Marc S. Hanover | Director, President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 70,000 | 70,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mark E. Mosteller | Vice President and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 105,000 | 105,000 | - | - | Employee Stock Option (Right to Buy) | |
| James T. Dalton | VP, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Ronald A. Morton | VP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 2,455 | 28,164 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2012 | 1,227 | 6,250 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2011 | 2,462 | 133,180 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2011 | 2,462 | 9,298,912 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2011 | 2,462 | 24,879 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2011 | 2,462 | 25,708 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2011 | 1,231 | 5,022 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Aug 2011 | 30,000 | 130,718 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2011 | 1,461 | 100,718 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2011 | 1,722 | 10,941,802 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2011 | 1,722 | 22,416 | - | - | Common Stock | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2011 | 1,722 | 86,557 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2011 | 1,878 | 23,246 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2011 | 861 | 3,791 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 28 Jun 2011 | 975,000 | 10,709,881 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Jun 2011 | 16,050 | 87,102 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2011 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2011 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2011 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2011 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2011 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2011 | 5,000 | 5,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Apr 2011 | 15,000 | 71,052 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2011 | 3,793 | 99,256 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2011 | 3,501 | 9,734,881 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2011 | 3,501 | 20,694 | - | - | Common Stock | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2011 | 3,501 | 84,835 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2011 | 3,793 | 21,367 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2011 | 1,750 | 2,930 | - | - | Common Stock | |
| Henry P. Doggrell | Vice President and Secretary | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Mar 2011 | 2,000 | 6,641 | - | - | Common Stock | |
| Henry P. Doggrell | Vice President and Secretary | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Mar 2011 | 2,500 | 5,000 | - | - | Common Stock | |
| Henry P. Doggrell | Vice President and Secretary | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Mar 2011 | 3,000 | 4,000 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 3,679 | 95,462 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 3,679 | 9,731,379 | - | - | Common Stock | |
| Henry P. Doggrell | Vice President and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 3,396 | 17,192 | - | - | Common Stock | |
| Gregory A. Deener | Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 3,396 | 81,333 | - | - | Common Stock | |
| Marc S. Hanover | Director, President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 70,000 | 70,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mark E. Mosteller | Vice President and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 105,000 | 105,000 | - | - | Employee Stock Option (Right to Buy) | |
| James T. Dalton | VP, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 50,000 | 50,000 | - | - | Employee Stock Option (Right to Buy) | |
| Ronald A. Morton | VP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 35,000 | 35,000 | - | - | Employee Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 3,396 | 17,573 | - | - | Common Stock | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 15,000 | 15,000 | - | - | Director Stock Option (Right to Buy) | |
| Barry Furr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2011 | 1,179 | 1,179 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Nov 2010 | 2,200,000 | 3,915,716 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Nov 2010 | 3,267,857 | 8,851,496 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2010 | 2,616 | 91,783 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2010 | 2,616 | 5,583,639 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2010 | 2,616 | 13,796 | - | - | Common Stock | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2010 | 2,616 | 77,937 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2010 | 2,616 | 14,177 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2010 | 20,000 | 89,167 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Aug 2010 | 10,000 | 69,167 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Aug 2010 | 20,000 | 59,167 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 Aug 2010 | 20,000 | 39,167 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2010 | 2,950 | 19,167 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2010 | 2,950 | 5,581,023 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2010 | 2,950 | 11,180 | - | - | Common Stock | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2010 | 2,950 | 75,320 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2010 | 2,704 | 11,560 | - | - | Common Stock | |
| J. Kenneth Glass | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jun 2010 | 7,500 | 56,052 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Jun 2010 | 44,133 | 1,715,716 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Jun 2010 | 166,139 | 1,671,583 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Jun 2010 | 75,000 | 1,505,444 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Jun 2010 | 48,580 | 1,430,444 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jun 2010 | 96,755 | 1,381,864 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jun 2010 | 90,000 | 1,285,109 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 27 May 2010 | 175,334 | 16,216 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 May 2010 | 200,000 | 1,045,109 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 May 2010 | 150,000 | 1,195,109 | - | - | Common Stock | |
| Gregory A. Deener | Vice President | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 May 2010 | 27,000 | 27,000 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 May 2010 | 2,794 | 845,109 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 May 2010 | 2,401 | 842,315 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 May 2010 | 25,000 | 839,914 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 May 2010 | 20,000 | 814,914 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 May 2010 | 20,000 | 794,914 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 May 2010 | 19,198 | 774,914 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 May 2010 | 20,000 | 735,716 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 May 2010 | 20,000 | 755,716 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2010 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2010 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| J. Kenneth Glass | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2010 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2010 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| Robert W. Karr | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2010 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2010 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Apr 2010 | 100,000 | 0 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Apr 2010 | 100,000 | 6,778,072 | - | - | Common Stock | |
| Timothy R.G. Sear | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2010 | 3,358 | 191,550 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2010 | 2,910 | 6,678,072 | - | - | Common Stock | |
| Michael G. Carter | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2010 | 2,910 | 8,229 | - | - | Common Stock | |
| John H. Pontius | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2010 | 2,686 | 72,370 | - | - | Common Stock | |
| Kenneth S. Robinson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2010 | 3,134 | 8,856 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Jan 2010 | 171,990 | 28,010 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Jan 2010 | 171,990 | 2,236,122 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Jan 2010 | 300,000 | 300,000 | - | - | Common Stock | |
| Mitchell S. Steiner | Director, Chief Executive Officer, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Jan 2010 | 300,000 | 1,936,122 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Jan 2010 | 300,000 | 6,675,162 | - | - | Common Stock | |
| J.R. Hyde | Director, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Jan 2010 | 300,000 | 0 | - | - | Common Stock |