155.4K XNAS Volume
XNAS 18 Mar, 2025 2:17 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 06 Mar 2025 | 8,015 | 78,034 | - | 6.9 | 55,223 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 70.65 per share. | 06 Mar 2025 | 3,678 | 74,356 | - | 70.7 | 259,851 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 71.92 per share. | 06 Mar 2025 | 22,016 | 52,340 | - | 71.9 | 1,583,391 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 72.60 per share. | 06 Mar 2025 | 4,306 | 48,034 | - | 72.6 | 312,616 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 06 Mar 2025 | 4,000 | 52,034 | - | 1.1 | 4,320 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 71.68 per share. | 06 Mar 2025 | 2,900 | 49,134 | - | 71.7 | 207,872 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 72.59 per share. | 06 Mar 2025 | 1,100 | 48,034 | - | 72.6 | 79,849 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Mar 2025 | 21,985 | 14,216 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Mar 2025 | 8,015 | 6,776 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Mar 2025 | 4,000 | 10,216 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 06 Mar 2025 | 21,985 | 70,019 | - | 1.1 | 23,744 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 78.49 per share. | 24 Feb 2025 | 1,382 | 216,824 | - | 78.5 | 108,473 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 79.13 per share. | 24 Feb 2025 | 302 | 216,522 | - | 79.1 | 23,897 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 77.51 per share. | 24 Feb 2025 | 316 | 218,206 | - | 77.5 | 24,493 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Feb 2025 | 27,000 | 285,780 | - | - | Stock Option (Right to Buy) | |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 18 Feb 2025 | 27,000 | 276,062 | - | 27.9 | 751,950 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 78.44 per share. | 18 Feb 2025 | 26,200 | 249,862 | - | 78.4 | 2,055,128 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 79.01 per share. | 18 Feb 2025 | 800 | 249,062 | - | 79.0 | 63,208 | Class A Common Stock |
| Henry E. Pelish | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.87 per share. | 31 Jan 2025 | 3,120 | 63,101 | - | 0.9 | 2,714 | Class A Common Stock |
| Henry E. Pelish | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2025 | 3,120 | 2,007 | - | - | Stock Option (Right to Buy) | |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 85.00 per share. | 27 Jan 2025 | 108 | 218,522 | - | 85 | 9,180 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 83.88 per share. | 27 Jan 2025 | 234 | 218,630 | - | 83.9 | 19,628 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 82.91 per share. | 27 Jan 2025 | 618 | 218,864 | - | 82.9 | 51,238 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 82.24 per share. | 27 Jan 2025 | 1,040 | 219,482 | - | 82.2 | 85,530 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2025 | 27,000 | 312,780 | - | - | Stock Option (Right to Buy) | |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 77.28 per share. | 15 Jan 2025 | 5,842 | 249,062 | - | 77.3 | 451,470 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 76.65 per share. | 15 Jan 2025 | 5,493 | 254,904 | - | 76.6 | 421,038 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 75.51 per share. | 15 Jan 2025 | 9,358 | 260,397 | - | 75.5 | 706,623 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 15 Jan 2025 | 27,000 | 276,062 | - | 27.9 | 751,950 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 74.94 per share. | 15 Jan 2025 | 6,307 | 269,755 | - | 74.9 | 472,647 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 18,750 | 66,563 | - | 0 | Class A Common Stock | |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 78.28 per share. | 06 Jan 2025 | 1,152 | 65,411 | - | 78.3 | 90,179 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 79.33 per share. | 06 Jan 2025 | 691 | 64,720 | - | 79.3 | 54,817 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 80.54 per share. | 06 Jan 2025 | 2,173 | 62,547 | - | 80.5 | 175,013 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 37,500 | 37,500 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 80.54 per share. | 06 Jan 2025 | 1,604 | 49,086 | - | 80.5 | 129,186 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 79.33 per share. | 06 Jan 2025 | 510 | 50,690 | - | 79.3 | 40,458 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 78.28 per share. | 06 Jan 2025 | 850 | 51,200 | - | 78.3 | 66,538 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 18,750 | 52,050 | - | 0 | Class A Common Stock | |
| Darlene Noci | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 18,750 | 52,050 | - | 0 | Class A Common Stock | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 78.28 per share. | 06 Jan 2025 | 1,152 | 50,898 | - | 78.3 | 90,179 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 79.33 per share. | 06 Jan 2025 | 691 | 50,207 | - | 79.3 | 54,817 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 80.54 per share. | 06 Jan 2025 | 2,173 | 48,034 | - | 80.5 | 175,013 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 37,500 | 37,500 | - | - | Stock Option (Right to Buy) | |
| Henry E. Pelish | Chief Scientific Officer | 06 Jan 2025 | 37,500 | 37,500 | - | - | Stock Option (Right to Buy) | ||
| Henry E. Pelish | Chief Scientific Officer | 06 Jan 2025 | 1,343 | 59,981 | - | 80.5 | 108,165 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 06 Jan 2025 | 428 | 61,324 | - | 79.3 | 33,953 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 06 Jan 2025 | 712 | 61,752 | - | 78.3 | 55,735 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 06 Jan 2025 | 18,750 | 62,464 | - | 0 | Class A Common Stock | ||
| Christopher D. Turner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 37,500 | 37,500 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 37,500 | 37,500 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 80.54 per share. | 06 Jan 2025 | 2,173 | 61,734 | - | 80.5 | 175,013 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 79.33 per share. | 06 Jan 2025 | 691 | 63,907 | - | 79.3 | 54,817 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 78.28 per share. | 06 Jan 2025 | 1,152 | 64,598 | - | 78.3 | 90,179 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 18,750 | 65,750 | - | 0 | Class A Common Stock | |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 80.54 per share. | 06 Jan 2025 | 9,360 | 249,062 | - | 80.5 | 753,854 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 79.33 per share. | 06 Jan 2025 | 2,979 | 258,422 | - | 79.3 | 236,324 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 78.28 per share. | 06 Jan 2025 | 4,962 | 261,401 | - | 78.3 | 388,425 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 56,250 | 266,363 | - | 0 | Class A Common Stock | |
| James R. Porter | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 112,500 | 112,500 | - | - | Stock Option (Right to Buy) | |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 83.62 per share. | 23 Dec 2024 | 1,409 | 221,113 | - | 83.6 | 117,821 | Class A Common Stock |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 84.17 per share. | 23 Dec 2024 | 591 | 220,522 | - | 84.2 | 49,744 | Class A Common Stock |
| Porter James R. | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.65 per share. | 19 Dec 2024 | 22,000 | 210,113 | - | 0.7 | 14,300 | Class A Common Stock |
| James Porter R. | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2024 | 22,000 | 565,942 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Dec 2024 | 4,728 | 196,156 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 17 Dec 2024 | 4,728 | 38,028 | - | 1.1 | 5,106 | Class A Common Stock |
| Balcom Alexandra | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 17 Dec 2024 | 8,972 | 47,000 | - | 6.9 | 61,817 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Dec 2024 | 8,972 | 87,226 | - | - | Stock Option (Right to Buy) | |
| R. Porter James | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 86.96 per share. | 16 Dec 2024 | 8,031 | 188,113 | - | 87.0 | 698,376 | Class A Common Stock |
| Pelish Henry E. | Chief Scientific Officer | 16 Dec 2024 | 5,914 | 0 | - | - | Stock Option (Right to Buy) | ||
| R. James Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 16 Dec 2024 | 27,000 | 215,113 | - | 27.9 | 751,950 | Class A Common Stock |
| Pelish Henry E. | Chief Scientific Officer | 16 Dec 2024 | 5,914 | 39,214 | - | 0.6 | 3,844 | Class A Common Stock | |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2024 | 27,000 | 339,780 | - | - | Stock Option (Right to Buy) | |
| E. Henry Pelish | Chief Scientific Officer | 16 Dec 2024 | 4,500 | 5,127 | - | - | Stock Option (Right to Buy) | ||
| James Porter R. | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 86.46 per share. | 16 Dec 2024 | 18,969 | 196,144 | - | 86.5 | 1,640,060 | Class A Common Stock |
| E. Henry Pelish | Chief Scientific Officer | 16 Dec 2024 | 4,500 | 43,714 | - | 0.9 | 3,915 | Class A Common Stock | |
| Hack A. F. Andrew | Director | Sale of securities on an exchange or to another person at price $ 88.00 per share. | 11 Dec 2024 | 1,250,000 | 1,447,267 | - | 88 | 110,000,000 | Class A Common Stock |
| Bogle C. Grant | Director | 05 Dec 2024 | 3,200 | 3,200 | - | 0 | Class A Common Stock | ||
| Grant C. Bogle | Director | 05 Dec 2024 | 4,851 | 4,851 | - | - | Stock Option (Right to Buy) | ||
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Nov 2024 | 10,000 | 84,200 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 96.25 per share. | 29 Nov 2024 | 1,858 | 33,300 | - | 96.3 | 178,833 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 95.69 per share. | 29 Nov 2024 | 8,142 | 35,158 | - | 95.7 | 779,108 | Class A Common Stock |
| Balcom Alexandra | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 29 Nov 2024 | 10,000 | 43,300 | - | 27.9 | 278,500 | Class A Common Stock |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 97.40 per share. | 25 Nov 2024 | 30 | 222,522 | - | 97.4 | 2,922 | Class A Common Stock |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 95.71 per share. | 25 Nov 2024 | 978 | 223,544 | - | 95.7 | 93,604 | Class A Common Stock |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 96.69 per share. | 25 Nov 2024 | 992 | 222,552 | - | 96.7 | 95,916 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 87.08 per share. | 15 Nov 2024 | 11,543 | 203,570 | - | 87.1 | 1,005,164 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Nov 2024 | 27,000 | 366,780 | - | - | Stock Option (Right to Buy) | |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 89.98 per share. | 15 Nov 2024 | 1,111 | 188,113 | - | 90.0 | 99,968 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 88.87 per share. | 15 Nov 2024 | 8,278 | 189,224 | - | 88.9 | 735,666 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 87.95 per share. | 15 Nov 2024 | 6,068 | 197,502 | - | 88.0 | 533,681 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 15 Nov 2024 | 27,000 | 215,113 | - | 27.9 | 751,950 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 87.99 per share. | 01 Nov 2024 | 1,987 | 36,313 | - | 88.0 | 174,836 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.40 per share. | 01 Nov 2024 | 5,000 | 38,300 | - | 14.4 | 72,000 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2024 | 5,000 | 29,161 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 90.03 per share. | 01 Nov 2024 | 500 | 33,300 | - | 90.0 | 45,015 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 88.79 per share. | 01 Nov 2024 | 2,513 | 33,800 | - | 88.8 | 223,129 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 89.17 per share. | 31 Oct 2024 | 6,320 | 35,000 | - | 89.2 | 563,554 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 90.31 per share. | 31 Oct 2024 | 1,600 | 33,400 | - | 90.3 | 144,496 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 90.94 per share. | 31 Oct 2024 | 100 | 33,300 | - | 90.9 | 9,094 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Oct 2024 | 10,000 | 94,200 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 31 Oct 2024 | 10,000 | 43,300 | - | 27.9 | 278,500 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 88.25 per share. | 31 Oct 2024 | 1,980 | 41,320 | - | 88.3 | 174,735 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 91.31 per share. | 28 Oct 2024 | 1,181 | 225,341 | - | 91.3 | 107,837 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 93.11 per share. | 28 Oct 2024 | 73 | 224,522 | - | 93.1 | 6,797 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 92.27 per share. | 28 Oct 2024 | 746 | 224,595 | - | 92.3 | 68,833 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 102.26 per share. | 15 Oct 2024 | 26,186 | 188,927 | - | 102.3 | 2,677,780 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 103.01 per share. | 15 Oct 2024 | 814 | 188,113 | - | 103.0 | 83,850 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 15 Oct 2024 | 27,000 | 215,113 | - | 27.9 | 751,950 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Oct 2024 | 27,000 | 393,780 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Oct 2024 | 5,000 | 35,800 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 01 Oct 2024 | 5,000 | 38,300 | - | 18.9 | 94,650 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 99.93 per share. | 01 Oct 2024 | 1,200 | 37,100 | - | 99.9 | 119,916 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 100.86 per share. | 01 Oct 2024 | 796 | 36,304 | - | 100.9 | 80,285 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 101.73 per share. | 01 Oct 2024 | 1,300 | 35,004 | - | 101.7 | 132,249 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 103.08 per share. | 01 Oct 2024 | 1,125 | 33,879 | - | 103.1 | 115,965 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 103.92 per share. | 01 Oct 2024 | 405 | 33,474 | - | 103.9 | 42,088 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 104.69 per share. | 01 Oct 2024 | 174 | 33,300 | - | 104.7 | 18,216 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 98.88 per share. | 30 Sep 2024 | 700 | 42,600 | - | 98.9 | 69,216 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2024 | 10,000 | 104,200 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 101.89 per share. | 30 Sep 2024 | 2,963 | 33,300 | - | 101.9 | 301,900 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 101.13 per share. | 30 Sep 2024 | 5,032 | 36,263 | - | 101.1 | 508,886 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 100.09 per share. | 30 Sep 2024 | 1,305 | 41,295 | - | 100.1 | 130,617 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 30 Sep 2024 | 10,000 | 43,300 | - | 27.9 | 278,500 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 101.34 per share. | 23 Sep 2024 | 356 | 228,166 | - | 101.3 | 36,077 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 106.50 per share. | 23 Sep 2024 | 6 | 226,545 | - | 106.5 | 639 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 107.83 per share. | 23 Sep 2024 | 23 | 226,522 | - | 107.8 | 2,480 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 105.36 per share. | 23 Sep 2024 | 163 | 226,551 | - | 105.4 | 17,174 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 104.54 per share. | 23 Sep 2024 | 230 | 226,714 | - | 104.5 | 24,044 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 103.16 per share. | 23 Sep 2024 | 101 | 226,944 | - | 103.2 | 10,419 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 102.29 per share. | 23 Sep 2024 | 1,121 | 227,045 | - | 102.3 | 114,667 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 16 Sep 2024 | 8,000 | 41,300 | - | 18.9 | 151,440 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Sep 2024 | 8,000 | 71,000 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 102.00 per share. | 16 Sep 2024 | 300 | 33,300 | - | 102 | 30,600 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 100.08 per share. | 16 Sep 2024 | 145 | 33,600 | - | 100.1 | 14,512 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 98.34 per share. | 16 Sep 2024 | 534 | 33,745 | - | 98.3 | 52,514 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 97.30 per share. | 16 Sep 2024 | 2,297 | 34,279 | - | 97.3 | 223,498 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 96.43 per share. | 16 Sep 2024 | 2,255 | 36,576 | - | 96.4 | 217,450 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 94.86 per share. | 16 Sep 2024 | 1,869 | 38,831 | - | 94.9 | 177,293 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 93.22 per share. | 16 Sep 2024 | 600 | 40,700 | - | 93.2 | 55,932 | Class A Common Stock |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 3,754 | 60,375 | - | 94.8 | 355,879 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 1,966 | 64,129 | - | 93.3 | 183,330 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 7,812 | 33,400 | - | 102.5 | 801,042 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 100 | 33,300 | - | 102.8 | 10,280 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 5,513 | 41,212 | - | 101.2 | 557,805 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 4,094 | 46,725 | - | 100.3 | 410,424 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 706 | 50,819 | - | 98.2 | 69,343 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 3,197 | 51,525 | - | 97.5 | 311,835 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 4,105 | 54,722 | - | 96.6 | 396,584 | Class A Common Stock | |
| Henry E. Pelish | Chief Scientific Officer | 16 Sep 2024 | 1,548 | 58,827 | - | 95.4 | 147,617 | Class A Common Stock | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 09 Sep 2024 | 3,000 | 36,300 | - | 6.9 | 20,670 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Sep 2024 | 3,000 | 173,608 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 89.11 per share. | 09 Sep 2024 | 161 | 33,300 | - | 89.1 | 14,347 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 88.37 per share. | 09 Sep 2024 | 2,311 | 33,461 | - | 88.4 | 204,223 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 87.69 per share. | 09 Sep 2024 | 288 | 35,772 | - | 87.7 | 25,255 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 86.34 per share. | 09 Sep 2024 | 240 | 36,060 | - | 86.3 | 20,722 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 03 Sep 2024 | 5,000 | 38,300 | - | 18.9 | 94,650 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Sep 2024 | 5,000 | 40,800 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 85.64 per share. | 03 Sep 2024 | 512 | 33,300 | - | 85.6 | 43,848 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 84.56 per share. | 03 Sep 2024 | 2,510 | 33,812 | - | 84.6 | 212,246 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 83.95 per share. | 03 Sep 2024 | 1,978 | 36,322 | - | 83.9 | 166,053 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 83.87 per share. | 30 Aug 2024 | 5,231 | 38,069 | - | 83.9 | 438,724 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Aug 2024 | 10,000 | 114,200 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 85.96 per share. | 30 Aug 2024 | 288 | 33,300 | - | 86.0 | 24,756 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 84.55 per share. | 30 Aug 2024 | 4,481 | 33,588 | - | 84.6 | 378,869 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 30 Aug 2024 | 10,000 | 43,300 | - | 27.9 | 278,500 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 85.53 per share. | 26 Aug 2024 | 156 | 228,522 | - | 85.5 | 13,343 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 84.79 per share. | 26 Aug 2024 | 1,047 | 228,678 | - | 84.8 | 88,775 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 83.81 per share. | 26 Aug 2024 | 797 | 229,725 | - | 83.8 | 66,797 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 23 Aug 2024 | 5,000 | 38,300 | - | 18.9 | 94,650 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 23 Aug 2024 | 6,000 | 44,300 | - | 27.9 | 167,100 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Aug 2024 | 6,000 | 90,154 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Aug 2024 | 5,000 | 79,000 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 85.04 per share. | 23 Aug 2024 | 11,000 | 33,300 | - | 85.0 | 935,440 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 85.02 per share. | 23 Aug 2024 | 3,334 | 2,507 | - | 85.0 | 283,457 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.79 per share. | 23 Aug 2024 | 3,334 | 5,841 | - | 13.8 | 45,976 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Aug 2024 | 3,334 | 23,333 | - | - | Stock Option (Right to Buy) | |
| Henry E. Pelish | Chief Scientific Officer | 23 Aug 2024 | 10,500 | 66,095 | - | 85.1 | 893,340 | Class A Common Stock | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 67.17 per share. | 08 Aug 2024 | 624 | 35,564 | - | 67.2 | 41,914 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 65.66 per share. | 08 Aug 2024 | 112 | 36,188 | - | 65.7 | 7,354 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 08 Aug 2024 | 3,000 | 36,300 | - | 6.9 | 20,670 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 69.95 per share. | 08 Aug 2024 | 374 | 33,300 | - | 69.9 | 26,161 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Aug 2024 | 3,000 | 176,608 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 69.34 per share. | 08 Aug 2024 | 1,794 | 33,674 | - | 69.3 | 124,396 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 67.95 per share. | 08 Aug 2024 | 96 | 35,468 | - | 67.9 | 6,523 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 01 Aug 2024 | 5,000 | 38,300 | - | 18.9 | 94,650 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Aug 2024 | 5,000 | 45,800 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 80.32 per share. | 01 Aug 2024 | 63 | 33,300 | - | 80.3 | 5,060 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 79.22 per share. | 01 Aug 2024 | 189 | 33,363 | - | 79.2 | 14,973 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 78.33 per share. | 01 Aug 2024 | 933 | 33,552 | - | 78.3 | 73,082 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 77.36 per share. | 01 Aug 2024 | 1,957 | 34,485 | - | 77.4 | 151,394 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 76.22 per share. | 01 Aug 2024 | 1,858 | 36,442 | - | 76.2 | 141,617 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 77.02 per share. | 31 Jul 2024 | 896 | 42,404 | - | 77.0 | 69,010 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jul 2024 | 10,000 | 124,200 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 81.31 per share. | 31 Jul 2024 | 1,135 | 33,300 | - | 81.3 | 92,287 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 80.38 per share. | 31 Jul 2024 | 1,649 | 34,435 | - | 80.4 | 132,547 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 79.44 per share. | 31 Jul 2024 | 5,723 | 36,084 | - | 79.4 | 454,635 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 78.05 per share. | 31 Jul 2024 | 597 | 41,807 | - | 78.1 | 46,596 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 31 Jul 2024 | 10,000 | 43,300 | - | 27.9 | 278,500 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 78.93 per share. | 29 Jul 2024 | 1,200 | 231,322 | - | 78.9 | 94,716 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 81.71 per share. | 29 Jul 2024 | 91 | 230,522 | - | 81.7 | 7,436 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 80.98 per share. | 29 Jul 2024 | 404 | 230,613 | - | 81.0 | 32,716 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 79.70 per share. | 29 Jul 2024 | 305 | 231,017 | - | 79.7 | 24,309 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jul 2024 | 5,000 | 26,667 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 80.29 per share. | 15 Jul 2024 | 1,900 | 4,907 | - | 80.3 | 152,551 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 79.43 per share. | 15 Jul 2024 | 700 | 6,807 | - | 79.4 | 55,601 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.79 per share. | 15 Jul 2024 | 5,000 | 7,507 | - | 13.8 | 68,950 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 81.93 per share. | 15 Jul 2024 | 205 | 2,507 | - | 81.9 | 16,796 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 81.40 per share. | 15 Jul 2024 | 2,195 | 2,712 | - | 81.4 | 178,673 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jul 2024 | 6,000 | 96,154 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 12 Jul 2024 | 6,000 | 39,300 | - | 27.9 | 167,100 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 80.16 per share. | 12 Jul 2024 | 6,000 | 33,300 | - | 80.2 | 480,960 | Class A Common Stock |
| Henry E. Pelish | Chief Scientific Officer | 09 Jul 2024 | 13,100 | 76,595 | - | 0 | Class A Common Stock | ||
| Henry E. Pelish | Chief Scientific Officer | 09 Jul 2024 | 18,600 | 18,600 | - | - | Stock Option (Right to Buy) | ||
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 08 Jul 2024 | 3,000 | 36,300 | - | 6.9 | 20,670 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jul 2024 | 3,000 | 179,608 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 73.84 per share. | 08 Jul 2024 | 699 | 33,300 | - | 73.8 | 51,614 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 73.39 per share. | 08 Jul 2024 | 1,739 | 33,999 | - | 73.4 | 127,625 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 71.97 per share. | 08 Jul 2024 | 562 | 35,738 | - | 72.0 | 40,447 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 75.46 per share. | 01 Jul 2024 | 4,458 | 33,842 | - | 75.5 | 336,401 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2024 | 5,000 | 50,800 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 01 Jul 2024 | 5,000 | 38,300 | - | 18.9 | 94,650 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 76.19 per share. | 01 Jul 2024 | 542 | 33,300 | - | 76.2 | 41,295 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 28 Jun 2024 | 10,000 | 43,300 | - | 27.9 | 278,500 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jun 2024 | 10,000 | 134,200 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 76.73 per share. | 28 Jun 2024 | 572 | 33,300 | - | 76.7 | 43,890 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 76.19 per share. | 28 Jun 2024 | 1,863 | 33,872 | - | 76.2 | 141,942 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 75.15 per share. | 28 Jun 2024 | 7,565 | 35,735 | - | 75.2 | 568,510 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 79.47 per share. | 24 Jun 2024 | 634 | 233,888 | - | 79.5 | 50,384 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 80.50 per share. | 24 Jun 2024 | 1,176 | 232,712 | - | 80.5 | 94,668 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 80.98 per share. | 24 Jun 2024 | 190 | 232,522 | - | 81.0 | 15,386 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.79 per share. | 14 Jun 2024 | 5,000 | 7,507 | - | 13.8 | 68,950 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 5,000 | 31,667 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 78.31 per share. | 14 Jun 2024 | 223 | 2,507 | - | 78.3 | 17,463 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 77.52 per share. | 14 Jun 2024 | 4,777 | 2,730 | - | 77.5 | 370,313 | Class A Common Stock |
| Anna Protopapas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,499 | - | 0 | Class A Common Stock | |
| Anna Protopapas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| Sapna Srivastava | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,499 | - | 0 | Class A Common Stock | |
| Sapna Srivastava | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| D. Gary Gilliland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,499 | - | 0 | Class A Common Stock | |
| D. Gary Gilliland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| Michael L. Meyers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| Michael L. Meyers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,499 | - | 0 | Class A Common Stock | |
| Cameron A. Wheeler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,499 | - | 0 | Class A Common Stock | |
| Cameron A. Wheeler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| Joseph Pearlberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,499 | - | 0 | Class A Common Stock | |
| Joseph Pearlberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| Matthew Shair | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 1,427,197 | - | 0 | Class A Common Stock | |
| Matthew Shair | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,507 | - | 0 | Class A Common Stock | |
| Andrew A. F. Hack | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 2,499 | 2,499 | - | - | Class A Common Stock | |
| Andrew A. F. Hack | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 3,789 | 3,789 | - | - | Stock Option (right to buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 06 Jun 2024 | 3,000 | 36,300 | - | 6.9 | 20,670 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2024 | 5,000 | 84,000 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2024 | 3,000 | 182,608 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 82.33 per share. | 06 Jun 2024 | 1,566 | 33,300 | - | 82.3 | 128,929 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 82.05 per share. | 06 Jun 2024 | 3,884 | 34,866 | - | 82.0 | 318,682 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 80.43 per share. | 06 Jun 2024 | 199 | 38,750 | - | 80.4 | 16,006 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 79.69 per share. | 06 Jun 2024 | 541 | 38,949 | - | 79.7 | 43,112 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 77.97 per share. | 06 Jun 2024 | 148 | 39,490 | - | 78.0 | 11,540 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 76.88 per share. | 06 Jun 2024 | 526 | 39,638 | - | 76.9 | 40,439 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 75.81 per share. | 06 Jun 2024 | 156 | 40,164 | - | 75.8 | 11,826 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 74.39 per share. | 06 Jun 2024 | 750 | 40,320 | - | 74.4 | 55,793 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 73.42 per share. | 06 Jun 2024 | 230 | 41,070 | - | 73.4 | 16,887 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 06 Jun 2024 | 5,000 | 41,300 | - | 18.9 | 94,650 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 66.87 per share. | 28 May 2024 | 1,256 | 235,266 | - | 66.9 | 83,989 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 67.79 per share. | 28 May 2024 | 728 | 234,538 | - | 67.8 | 49,351 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 68.62 per share. | 28 May 2024 | 16 | 234,522 | - | 68.6 | 1,098 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.36 per share. | 15 May 2024 | 1,667 | 1,675 | - | 9.4 | 15,603 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 1,667 | 0 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 69.09 per share. | 15 May 2024 | 5,000 | 8 | - | 69.1 | 345,450 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 3,333 | 36,667 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.79 per share. | 15 May 2024 | 3,333 | 5,008 | - | 13.8 | 45,962 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 66.12 per share. | 13 May 2024 | 13,129 | 1,429,160 | - | 66.1 | 868,089 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 66.86 per share. | 13 May 2024 | 4,462 | 1,424,698 | - | 66.9 | 298,329 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 65.42 per share. | 13 May 2024 | 19,909 | 1,442,289 | - | 65.4 | 1,302,447 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 70.27 per share. | 06 May 2024 | 7,900 | 1,462,198 | - | 70.3 | 555,133 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 69.27 per share. | 06 May 2024 | 29,600 | 1,470,098 | - | 69.3 | 2,050,392 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 May 2024 | 3,000 | 185,608 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 73.13 per share. | 02 May 2024 | 138 | 33,300 | - | 73.1 | 10,092 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 72.58 per share. | 02 May 2024 | 1,296 | 33,438 | - | 72.6 | 94,064 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 71.55 per share. | 02 May 2024 | 1,566 | 34,734 | - | 71.5 | 112,047 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 02 May 2024 | 3,000 | 36,300 | - | 6.9 | 20,670 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 67.01 per share. | 29 Apr 2024 | 833 | 237,689 | - | 67.0 | 55,819 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 68.57 per share. | 29 Apr 2024 | 1,600 | 1,499,698 | - | 68.6 | 109,712 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 67.81 per share. | 29 Apr 2024 | 20,207 | 1,501,298 | - | 67.8 | 1,370,237 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 67.01 per share. | 29 Apr 2024 | 15,693 | 1,521,505 | - | 67.0 | 1,051,588 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 68.56 per share. | 29 Apr 2024 | 85 | 236,522 | - | 68.6 | 5,828 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 67.81 per share. | 29 Apr 2024 | 1,082 | 236,607 | - | 67.8 | 73,370 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 62.66 per share. | 22 Apr 2024 | 14,156 | 1,560,542 | - | 62.7 | 887,015 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 64.52 per share. | 22 Apr 2024 | 14,650 | 1,537,198 | - | 64.5 | 945,218 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 63.80 per share. | 22 Apr 2024 | 8,694 | 1,551,848 | - | 63.8 | 554,677 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 65.27 per share. | 15 Apr 2024 | 25,600 | 1,586,598 | - | 65.3 | 1,670,912 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 66.17 per share. | 15 Apr 2024 | 11,900 | 1,574,698 | - | 66.2 | 787,423 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.36 per share. | 15 Apr 2024 | 5,000 | 5,008 | - | 9.4 | 46,800 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Apr 2024 | 5,000 | 1,667 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 65.52 per share. | 15 Apr 2024 | 4,994 | 14 | - | 65.5 | 327,207 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 66.67 per share. | 15 Apr 2024 | 6 | 8 | - | 66.7 | 400 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 69.64 per share. | 08 Apr 2024 | 1,000 | 1,612,198 | - | 69.6 | 69,640 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 68.63 per share. | 08 Apr 2024 | 25,478 | 1,613,198 | - | 68.6 | 1,748,555 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 67.89 per share. | 08 Apr 2024 | 11,022 | 1,638,676 | - | 67.9 | 748,284 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 72.69 per share. | 04 Apr 2024 | 400 | 35,169 | - | 72.7 | 29,076 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 71.54 per share. | 04 Apr 2024 | 731 | 35,569 | - | 71.5 | 52,296 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 04 Apr 2024 | 3,000 | 36,300 | - | 6.9 | 20,670 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Apr 2024 | 3,000 | 188,608 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 74.81 per share. | 04 Apr 2024 | 1,491 | 33,300 | - | 74.8 | 111,542 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 73.74 per share. | 04 Apr 2024 | 378 | 34,791 | - | 73.7 | 27,874 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 77.19 per share. | 01 Apr 2024 | 9,694 | 1,649,698 | - | 77.2 | 748,280 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 76.82 per share. | 01 Apr 2024 | 27,806 | 1,659,392 | - | 76.8 | 2,136,057 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 28 Mar 2024 | 13,000 | 46,300 | - | 18.9 | 246,090 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Mar 2024 | 9,000 | 102,154 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Mar 2024 | 13,000 | 89,000 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 75.94 per share. | 28 Mar 2024 | 3,044 | 33,300 | - | 75.9 | 231,161 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 75.22 per share. | 28 Mar 2024 | 16,208 | 36,344 | - | 75.2 | 1,219,166 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 74.23 per share. | 28 Mar 2024 | 2,748 | 52,552 | - | 74.2 | 203,984 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 28 Mar 2024 | 9,000 | 55,300 | - | 27.9 | 250,650 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 76.74 per share. | 25 Mar 2024 | 1,895 | 238,627 | - | 76.7 | 145,422 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 77.37 per share. | 25 Mar 2024 | 1,955 | 1,687,198 | - | 77.4 | 151,258 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 76.74 per share. | 25 Mar 2024 | 35,545 | 1,689,153 | - | 76.7 | 2,727,723 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 77.37 per share. | 25 Mar 2024 | 105 | 238,522 | - | 77.4 | 8,124 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 22 Mar 2024 | 10,000 | 43,300 | - | 1.1 | 10,800 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2024 | 10,000 | 34,161 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2024 | 10,000 | 36,201 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 78.72 per share. | 22 Mar 2024 | 600 | 33,300 | - | 78.7 | 47,232 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 77.94 per share. | 22 Mar 2024 | 6,300 | 33,900 | - | 77.9 | 491,022 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 77.25 per share. | 22 Mar 2024 | 13,100 | 40,200 | - | 77.3 | 1,011,975 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.40 per share. | 22 Mar 2024 | 10,000 | 53,300 | - | 14.4 | 144,000 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 79.81 per share. | 15 Mar 2024 | 2,127 | 11,214 | - | 79.8 | 169,756 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.36 per share. | 15 Mar 2024 | 13,333 | 13,341 | - | 9.4 | 124,797 | Class A Common Stock |
| Emily Drabant Conley | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2024 | 13,333 | 6,667 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 84.44 per share. | 15 Mar 2024 | 1,000 | 8 | - | 84.4 | 84,440 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 82.32 per share. | 15 Mar 2024 | 200 | 1,008 | - | 82.3 | 16,464 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 81.25 per share. | 15 Mar 2024 | 2,321 | 1,208 | - | 81.2 | 188,581 | Class A Common Stock |
| Emily Drabant Conley | Director | Sale of securities on an exchange or to another person at price $ 80.63 per share. | 15 Mar 2024 | 7,685 | 3,529 | - | 80.6 | 619,642 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 47,500 | 47,500 | - | - | Stock Option (Right to Buy) | |
| Miller Deborah | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 47,500 | 47,500 | - | - | Stock Option (Right to Buy) | |
| R. James Porter | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 161,100 | 161,100 | - | - | Stock Option (Right to Buy) | |
| Turner D. Christopher | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 47,500 | 47,500 | - | - | Stock Option (Right to Buy) | |
| D. Turner Christopher | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 33,300 | 47,813 | - | 0 | Class A Common Stock | |
| Noci Darlene | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 33,300 | 33,300 | - | 0 | Class A Common Stock | |
| James Porter R. | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 112,800 | 188,113 | - | 0 | Class A Common Stock | |
| Noci Darlene | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 47,500 | 47,500 | - | - | Stock Option (Right to Buy) | |
| Miller Deborah | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 33,300 | 33,300 | - | 0 | Class A Common Stock | |
| Alexandra Balcom | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2024 | 33,300 | 33,300 | - | 0 | Class A Common Stock | |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 75.20 per share. | 26 Dec 2023 | 35,056 | 1,738,190 | - | 75.2 | 2,636,211 | Class A Common Stock |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 74.22 per share. | 26 Dec 2023 | 937 | 1,842,911 | - | 74.2 | 69,544 | Class A Common Stock |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 75.17 per share. | 26 Dec 2023 | 1,000 | 1,773,246 | - | 75.2 | 75,170 | Class A Common Stock |
| Shair Matthew | Director | Sale of securities on an exchange or to another person at price $ 75.13 per share. | 26 Dec 2023 | 68,665 | 1,774,246 | - | 75.1 | 5,158,801 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 76.14 per share. | 26 Dec 2023 | 13,492 | 1,724,698 | - | 76.1 | 1,027,281 | Class A Common Stock |
| Noci Darlene | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 18 Dec 2023 | 22,601 | 22,601 | - | 1.1 | 24,409 | Class A Common Stock |
| Protopapas Anna | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 5,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Noci Darlene | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 75.82 per share. | 18 Dec 2023 | 40,000 | 0 | - | 75.8 | 3,032,800 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.40 per share. | 18 Dec 2023 | 5,839 | 40,000 | - | 14.4 | 84,082 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 30,000 | 200,884 | - | - | Stock Option (Right to Buy) | |
| Noci Darlene | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 22,601 | 46,201 | - | - | Stock Option (Right to Buy) | |
| Noci Darlene | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 5,839 | 44,161 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 5,000 | 102,000 | - | - | Stock Option (Right to Buy) | |
| Miller Deborah | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 75.00 per share. | 18 Dec 2023 | 5,000 | 0 | - | 75 | 375,000 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 75.82 per share. | 18 Dec 2023 | 33,046 | 0 | - | 75.8 | 2,505,548 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.93 per share. | 18 Dec 2023 | 5,000 | 5,000 | - | 18.9 | 94,650 | Class A Common Stock |
| Balcom Alexandra | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 75.82 per share. | 18 Dec 2023 | 30,000 | 0 | - | 75.8 | 2,274,600 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 11,560 | 14,791 | - | - | Stock Option (Right to Buy) | |
| Miller Deborah | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 33,046 | 111,154 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 18 Dec 2023 | 11,560 | 34,161 | - | 6.9 | 79,648 | Class A Common Stock |
| Anna Protopapas | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.36 per share. | 18 Dec 2023 | 5,000 | 5,000 | - | 9.4 | 46,800 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 27.85 per share. | 18 Dec 2023 | 33,046 | 33,046 | - | 27.8 | 920,331 | Class A Common Stock |
| Protopapas Anna | Director | Sale of securities on an exchange or to another person at price $ 75.67 per share. | 18 Dec 2023 | 5,000 | 0 | - | 75.7 | 378,350 | Class A Common Stock |
| Balcom Alexandra | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 18 Dec 2023 | 30,000 | 30,000 | - | 1.1 | 32,400 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 15 Aug 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2023 | 2,000 | 193,608 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 43.01 per share. | 15 Aug 2023 | 709 | 0 | - | 43.0 | 30,494 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 42.46 per share. | 15 Aug 2023 | 1,291 | 709 | - | 42.5 | 54,816 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 50.07 per share. | 01 Aug 2023 | 2,036 | 0 | - | 50.1 | 101,943 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 01 Aug 2023 | 3,000 | 3,000 | - | 1.1 | 3,240 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 49.69 per share. | 01 Aug 2023 | 964 | 2,036 | - | 49.7 | 47,901 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Aug 2023 | 3,000 | 82,389 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 31 Jul 2023 | 25,000 | 25,000 | - | 1.1 | 27,000 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jul 2023 | 25,000 | 230,884 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 49.49 per share. | 31 Jul 2023 | 10,848 | 0 | - | 49.5 | 536,868 | Class A Common Stock |
| Alexandra Balcom | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 48.61 per share. | 31 Jul 2023 | 14,152 | 10,848 | - | 48.6 | 687,929 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 28 Jul 2023 | 6,500 | 6,500 | - | 6.9 | 44,785 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 48.52 per share. | 28 Jul 2023 | 6,500 | 0 | - | 48.5 | 315,380 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jul 2023 | 6,500 | 195,608 | - | - | Stock Option (Right to Buy) | |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 46.85 per share. | 26 Jul 2023 | 2,365 | 14,513 | - | 46.8 | 110,800 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jul 2023 | 2,665 | 311,100 | - | - | Stock Option (Right to Buy) | |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jul 2023 | 2,365 | 313,765 | - | - | Stock Option (Right to Buy) | |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 48.93 per share. | 26 Jul 2023 | 2,665 | 14,513 | - | 48.9 | 130,398 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 26 Jul 2023 | 2,665 | 17,178 | - | 6.9 | 18,362 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 26 Jul 2023 | 2,365 | 16,878 | - | 6.9 | 16,295 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 46.80 per share. | 20 Jul 2023 | 100 | 14,513 | - | 46.8 | 4,680 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Jul 2023 | 200 | 316,130 | - | - | Stock Option (Right to Buy) | |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Jul 2023 | 100 | 316,330 | - | - | Stock Option (Right to Buy) | |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 46.82 per share. | 20 Jul 2023 | 200 | 14,513 | - | 46.8 | 9,364 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 20 Jul 2023 | 200 | 14,713 | - | 6.9 | 1,378 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 20 Jul 2023 | 100 | 14,613 | - | 6.9 | 689 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 19 Jul 2023 | 4,559 | 4,559 | - | 1.1 | 4,924 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jul 2023 | 10,941 | 85,389 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jul 2023 | 4,559 | 96,330 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 45.17 per share. | 19 Jul 2023 | 10,941 | 0 | - | 45.2 | 494,205 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 19 Jul 2023 | 10,941 | 10,941 | - | 1.1 | 11,816 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 45.04 per share. | 19 Jul 2023 | 4,559 | 0 | - | 45.0 | 205,337 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 41.19 per share. | 17 Jul 2023 | 162 | 1,838 | - | 41.2 | 6,673 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jul 2023 | 2,000 | 202,108 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 43.93 per share. | 17 Jul 2023 | 298 | 0 | - | 43.9 | 13,091 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 43.09 per share. | 17 Jul 2023 | 1,540 | 298 | - | 43.1 | 66,359 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 17 Jul 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 41.33 per share. | 03 Jul 2023 | 2,447 | 553 | - | 41.3 | 101,135 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jul 2023 | 3,000 | 100,889 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 42.12 per share. | 03 Jul 2023 | 553 | 0 | - | 42.1 | 23,292 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 03 Jul 2023 | 3,000 | 3,000 | - | 1.1 | 3,240 | Class A Common Stock |
| Anna Protopapas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Sapna Srivastava | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| D. Gary Gilliland | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Andrew A. F. Hack | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Michael L. Meyers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Cameron Wheeler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 44.86 per share. | 15 Jun 2023 | 164 | 0 | - | 44.9 | 7,357 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 44.39 per share. | 15 Jun 2023 | 1,641 | 164 | - | 44.4 | 72,844 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2023 | 2,000 | 204,108 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 42.89 per share. | 15 Jun 2023 | 195 | 1,805 | - | 42.9 | 8,364 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 15 Jun 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 45.19 per share. | 15 Jun 2023 | 2,900 | 0 | - | 45.2 | 131,051 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 15 Jun 2023 | 1,000 | 1,000 | - | 1.1 | 1,080 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 45.07 per share. | 15 Jun 2023 | 1,000 | 0 | - | 45.1 | 45,070 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 15 Jun 2023 | 2,900 | 2,900 | - | 1.1 | 3,132 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2023 | 1,000 | 106,789 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2023 | 2,900 | 103,889 | - | - | Stock Option (Right to Buy) | |
| Joseph Pearlberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Matthew Shair | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Emily Drabant Conley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 05 Jun 2023 | 10,235 | 24,748 | - | 6.9 | 70,519 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 44.86 per share. | 05 Jun 2023 | 10,235 | 14,513 | - | 44.9 | 459,142 | Class A Common Stock |
| Christopher D. Turner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2023 | 10,235 | 316,430 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2023 | 600 | 107,789 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 45.00 per share. | 05 Jun 2023 | 600 | 0 | - | 45 | 27,000 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 05 Jun 2023 | 600 | 600 | - | 1.1 | 648 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2023 | 3,000 | 108,389 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 42.36 per share. | 01 Jun 2023 | 1,389 | 1,372 | - | 42.4 | 58,838 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 01 Jun 2023 | 3,000 | 3,000 | - | 1.1 | 3,240 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 41.46 per share. | 01 Jun 2023 | 239 | 2,761 | - | 41.5 | 9,909 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 43.13 per share. | 01 Jun 2023 | 1,372 | 0 | - | 43.1 | 59,174 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 40.31 per share. | 15 May 2023 | 502 | 1,498 | - | 40.3 | 20,236 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 15 May 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 40.89 per share. | 15 May 2023 | 1,498 | 0 | - | 40.9 | 61,253 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 2,000 | 206,138 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 39.63 per share. | 05 May 2023 | 1,332 | 0 | - | 39.6 | 52,787 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 05 May 2023 | 2,800 | 2,800 | - | 6.9 | 19,292 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 May 2023 | 2,800 | 209,470 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 May 2023 | 1,332 | 208,138 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 05 May 2023 | 1,332 | 1,332 | - | 6.9 | 9,177 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 39.64 per share. | 05 May 2023 | 2,800 | 0 | - | 39.6 | 110,992 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 39.61 per share. | 01 May 2023 | 900 | 0 | - | 39.6 | 35,649 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 900 | 212,270 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 01 May 2023 | 900 | 900 | - | 6.9 | 6,201 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 35.71 per share. | 01 May 2023 | 28 | 2,972 | - | 35.7 | 1,000 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 01 May 2023 | 3,000 | 3,000 | - | 1.1 | 3,240 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 3,000 | 111,389 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 39.58 per share. | 01 May 2023 | 50 | 0 | - | 39.6 | 1,979 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 38.81 per share. | 01 May 2023 | 2,282 | 50 | - | 38.8 | 88,564 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 38.03 per share. | 01 May 2023 | 549 | 2,332 | - | 38.0 | 20,878 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 36.98 per share. | 01 May 2023 | 91 | 2,881 | - | 37.0 | 3,365 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 30.15 per share. | 17 Apr 2023 | 1,875 | 0 | - | 30.1 | 56,531 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 17 Apr 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.33 per share. | 17 Apr 2023 | 125 | 1,875 | - | 29.3 | 3,666 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Apr 2023 | 2,000 | 213,170 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Apr 2023 | 3,000 | 114,389 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 27.06 per share. | 03 Apr 2023 | 112 | 0 | - | 27.1 | 3,031 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 26.57 per share. | 03 Apr 2023 | 2,888 | 112 | - | 26.6 | 76,734 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 03 Apr 2023 | 3,000 | 3,000 | - | 1.1 | 3,240 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2023 | 2,000 | 215,170 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 15 Mar 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 28.17 per share. | 15 Mar 2023 | 1,839 | 161 | - | 28.2 | 51,805 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.22 per share. | 15 Mar 2023 | 161 | 0 | - | 29.2 | 4,704 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 01 Mar 2023 | 3,000 | 3,000 | - | 1.1 | 3,240 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2023 | 3,000 | 117,389 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 30.35 per share. | 01 Mar 2023 | 400 | 0 | - | 30.4 | 12,140 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 29.81 per share. | 01 Mar 2023 | 2,600 | 400 | - | 29.8 | 77,506 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 15 Feb 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2023 | 2,000 | 217,140 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 30.19 per share. | 15 Feb 2023 | 158 | 0 | - | 30.2 | 4,770 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.51 per share. | 15 Feb 2023 | 1,842 | 158 | - | 29.5 | 54,357 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 29.37 per share. | 02 Feb 2023 | 1,988 | 1,012 | - | 29.4 | 58,388 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2023 | 3,000 | 120,389 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 29.92 per share. | 02 Feb 2023 | 1,012 | 0 | - | 29.9 | 30,279 | Class A Common Stock |
| Darlene Noci | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.08 per share. | 02 Feb 2023 | 3,000 | 3,000 | - | 1.1 | 3,240 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 32.15 per share. | 17 Jan 2023 | 709 | 1,291 | - | 32.1 | 22,794 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jan 2023 | 2,000 | 219,140 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 32.88 per share. | 17 Jan 2023 | 1,291 | 0 | - | 32.9 | 42,448 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.89 per share. | 17 Jan 2023 | 2,000 | 2,000 | - | 6.9 | 13,780 | Class A Common Stock |
| James R. Porter | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 420,780 | 420,780 | - | - | Stock Option (Right to Buy) | |
| Alexandra Balcom | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 144,200 | 144,200 | - | - | Stock Option (Right to Buy) | |
| Christopher D. Turner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 144,200 | 144,200 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 144,200 | 144,200 | - | - | Stock Option (Right to Buy) | |
| Darlene Noci | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2023 | 144,200 | 144,200 | - | - | Stock Option (Right to Buy) | |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 27.92 per share. | 04 Jan 2023 | 16,016 | 1,946,982 | - | 27.9 | 447,167 | Class A Common Stock |
| Matthew Shair | Director | Sale of securities on an exchange or to another person at price $ 28.87 per share. | 04 Jan 2023 | 2,284 | 1,944,698 | - | 28.9 | 65,939 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Nov 2022 | 2,000 | 223,140 | - | - | Stock Option (Right to Buy) | |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 31.91 per share. | 15 Nov 2022 | 1,000 | 400 | - | 31.9 | 31,910 | Class A Common Stock |
| Deborah Miller | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 31.24 per share. | 15 Nov 2022 | 600 | 1,400 | - | 31.2 | 18,744 | Class A Common Stock |