567.3K XNAS Volume
XNAS 19 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Beth A. Taylor | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 40,000 | 148,368 (1%) | 0% | 0 | Common Stock | |
| Michael J. Harrington | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 39,392 | 76,892 (0%) | 0% | 0 | Common Stock | |
| Terry Coelho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 39,392 | 79,803 (0%) | 0% | 0 | Common Stock | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 30,000 | 737,816 (6%) | 0% | 0 | Common Stock | |
| Nigel Brown | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 39,392 | 104,929 (0%) | 0% | 0 | Common Stock | |
| Brennan Freeman | VP-Finance & Corp. Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 15,000 | 42,478 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 25,000 | 53,557 (0%) | 0% | 0 | Common Stock | |
| David Landman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 39,392 | 216,243 (1%) | 0% | 0 | Common Stock | |
| Andrea Castetter | SVP, Gen. Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 35,000 | 55,000 (0%) | 0% | 0 | Common Stock | |
| R. Matthew Neff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 39,392 | 155,102 (1%) | 0% | 0 | Common Stock | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 429,730 | 1,386,322 (12%) | 3% | 0 | Common Stock | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 429,730 | 429,730 | - | - | Employee Stock Option (right to buy) | |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 25,000 | 186,761 (1%) | 0% | 0 | Common Stock | |
| Adrian Hardy | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 25,000 | 58,420 (0%) | 0% | 0 | Common Stock | |
| Beth A. Taylor | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 6,500 | 6,500 | - | - | Employee Stock Option (right to buy) | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 6,500 | 6,500 | - | - | Employee Stock Option (right to buy) | |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 6,500 | 6,500 | - | - | Employee Stock Option (right to buy) | |
| Adrian Hardy | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 6,500 | 6,500 | - | - | Employee Stock Option (right to buy) | |
| Brennan Freeman | VP-Finance & Corp. Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 3,750 | 3,750 | - | - | Employee Stock Option (right to buy) | |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 6,500 | 6,500 | - | - | Employee Stock Option (right to buy) | |
| Andrea Castetter | SVP, Gen. Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 6,500 | 6,500 | - | - | Employee Stock Option (right to buy) | |
| Beth A. Taylor | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.01 per share. | 18 Feb 2025 | 4,370 | 108,368 (1%) | 0% | 4.0 | 17,507 | Common Stock |
| John E. Sagartz | Director, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 3.94 per share. | 18 Feb 2025 | 2,113 | 707,816 (6%) | 0% | 3.9 | 8,316 | Common Stock |
| Robert W. Leasure | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.82 per share. | 18 Feb 2025 | 73,617 | 956,592 (8%) | 0% | 3.8 | 281,136 | Common Stock |
| Brennan Freeman | VP-Finance & Corp. Controller | Sale of securities on an exchange or to another person at price $ 4.04 per share. | 18 Feb 2025 | 1,339 | 27,478 (0%) | 0% | 4.0 | 5,416 | Common Stock |
| Beth A. Taylor | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.46 per share. | 31 Jan 2025 | 2,054 | 112,738 (1%) | 0% | 4.5 | 9,171 | Common Stock |
| John E. Sagartz | Director, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 4.48 per share. | 31 Jan 2025 | 2,118 | 709,929 (6%) | 0% | 4.5 | 9,479 | Common Stock |
| Robert W. Leasure | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.15 per share. | 31 Jan 2025 | 22,700 | 1,030,209 (9%) | 0% | 4.2 | 94,298 | Common Stock |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 4.48 per share. | 31 Jan 2025 | 2,036 | 29,029 (0%) | 0% | 4.5 | 9,123 | Common Stock |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 4.18 per share. | 31 Jan 2025 | 472 | 28,557 (0%) | 0% | 4.2 | 1,973 | Common Stock |
| Andrea Castetter | SVP, Gen. Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| Landman David | Director | Purchase of securities on an exchange or from another person at price $ 4.25 per share. | 19 Dec 2024 | 23,529 | 176,851 (1%) | 0% | 4.2 | 99,998 | Common Stock |
| Nigel Brown | Director | Purchase of securities on an exchange or from another person at price $ 4.26 per share. | 10 Dec 2024 | 7,500 | 65,537 (0%) | 0% | 4.3 | 31,950 | Common Stock |
| Beattie John Gregory | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 4.75 per share. | 10 Dec 2024 | 30,000 | 161,761 (1%) | 0% | 4.8 | 142,500 | Common Stock |
| Michael J. Harrington | Director | Purchase of securities on an exchange or from another person at price $ 3.98 per share. | 06 Dec 2024 | 10,000 | 37,500 (0%) | 0% | 4.0 | 39,822 | Common Stock |
| David Landman | Director | Purchase of securities on an exchange or from another person at price $ 4.14 per share. | 06 Dec 2024 | 100,000 | 153,322 (1%) | 0% | 4.1 | 414,000 | Common Stock |
| Beth A. Taylor | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 114,792 (1%) | 0% | 0 | Common Stock | |
| Beth A. Taylor | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Michael J. Harrington | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 27,500 | 27,500 (0%) | 0% | 0 | Common Stock | |
| R. Matthew Neff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 27,500 | 115,710 (1%) | 0% | 0 | Common Stock | |
| Terry Coelho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 27,500 | 40,411 (0%) | 0% | 0 | Common Stock | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 712,047 (6%) | 0% | 0 | Common Stock | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 300,000 | 1,052,909 (9%) | 2% | 0 | Common Stock | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 300,000 | 300,000 | - | - | Employee Stock Option (right to buy) | |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 131,761 (1%) | 0% | 0 | Common Stock | |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Nigel Brown | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 27,500 | 58,037 (0%) | 0% | 0 | Common Stock | |
| Adrian Hardy | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Adrian Hardy | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 33,420 (0%) | 0% | 0 | Common Stock | |
| Brennan Freeman | VP-Finance & Corp. Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 28,817 (0%) | 0% | 0 | Common Stock | |
| Brennan Freeman | VP-Finance & Corp. Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 31,065 (0%) | 0% | 0 | Common Stock | |
| David Landman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 27,500 | 53,322 (0%) | 0% | 0 | Common Stock | |
| Andrea Castetter | SVP, Gen. Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 (0%) | 0% | 0 | Common Stock | |
| Andrea Castetter | SVP, Gen. Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2024 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Andrea Castetter | SVP, Gen. Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2024 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| Freeman Brennan | VP-Finance & Corp. Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 4,375 | 4,375 | - | - | Employee Stock Option (right to buy) | |
| Arthur Krupp Jeffrey | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 3,750 | 3,750 | - | - | Employee Stock Option (right to buy) | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 6,250 | 6,250 | - | - | Employee Stock Option (right to buy) | |
| A. Beth Taylor | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 6,250 | 6,250 | - | - | Employee Stock Option (right to buy) | |
| Beattie John Gregory | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 3.12 per share. | 14 Dec 2023 | 47,966 | 111,761 (1%) | 0% | 3.1 | 149,836 | Common Stock |
| Michael Garrett | Chief Commercial Officer | Purchase of securities on an exchange or from another person at price $ 2.83 per share. | 14 Dec 2023 | 5,000 | 16,467 (0%) | 0% | 2.8 | 14,145 | Common Stock |
| Beattie Gregory John | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Dec 2023 | 7,500 | 7,500 | - | - | Employee Stock Option (right to buy) | |
| Michael Garrett | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Dec 2023 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| Richard Allen Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2023 | 25,822 | 97,780 (0%) | 0% | 0 | Common Stock | |
| Gregory C. Davis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2023 | 25,822 | 67,780 (0%) | 0% | 0 | Common Stock | |
| R. Matthew Neff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2023 | 25,822 | 88,210 (0%) | 0% | 0 | Common Stock | |
| Nigel Brown | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2023 | 25,822 | 30,537 (0%) | 0% | 0 | Common Stock | |
| David Landman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2023 | 25,822 | 25,822 (0%) | 0% | 0 | Common Stock | |
| Beraldi Fernanda | Former Genl Counsel & Secy | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2023 | 2,500 | 7,840 (0%) | 0% | 0 | Common Stock | |
| John E. Sagartz | Director, Chief Strategy Officer | Purchase of securities on an exchange or from another person at price $ 4.91 per share. | 14 Mar 2023 | 5,100 | 692,047 (6%) | 0% | 4.9 | 25,041 | Common Stock |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 6.99 per share. | 22 Feb 2023 | 5,000 | 63,795 (0%) | 0% | 7.0 | 34,950 | Common Stock |
| Beth A. Taylor | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2023 | 5,000 | 94,792 (0%) | 0% | 0 | Common Stock | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2023 | 151,706 | 151,706 | - | - | Employee Stock Option (right to buy) | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2023 | 151,706 | 845,409 (7%) | 1% | 0 | Common Stock | |
| Brennan Freeman | VP-Finance & Corp. Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2023 | 4,000 | 8,817 (0%) | 0% | 0 | Common Stock | |
| Beth A. Taylor | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 5,917 | 89,792 (0%) | 0% | 0 | Common Stock | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 5,917 | 686,947 (6%) | 0% | 0 | Common Stock | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 59,172 | 693,703 (6%) | 0% | 0 | Common Stock | |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 7,101 | 58,795 (0%) | 0% | 0 | Common Stock | |
| Michael Garrett | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 9,467 | 11,467 (0%) | 0% | 0 | Common Stock | |
| Fernanda Beraldi | General Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 2,840 | 5,340 (0%) | 0% | 0 | Common Stock | |
| Brennan Freeman | VP-Finance & Corp. Controller | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 4,142 | 4,817 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 5,000 | 11,065 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Arthur Krupp | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jan 2023 | 1,065 | 6,065 (0%) | 0% | 0 | Common Stock | |
| William D. Pitchford | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 5.82 per share. | 09 Dec 2022 | 2,123 | 74,051 (0%) | 0% | 5.8 | 12,366 | Common Stock |
| R. Matthew Neff | Director | Sale of securities on an exchange or to another person at price $ 6.12 per share. | 01 Dec 2022 | 1,000 | 62,388 (0%) | 0% | 6.1 | 6,120 | Common Stock |
| R. Matthew Neff | Director | Sale of securities on an exchange or to another person at price $ 21.12 per share. | 01 Nov 2022 | 500 | 63,888 (0%) | 0% | 21.1 | 10,560 | Common Stock |
| R. Matthew Neff | Director | Sale of securities on an exchange or to another person at price $ 21.13 per share. | 01 Nov 2022 | 500 | 63,388 (0%) | 0% | 21.1 | 10,563 | Common Stock |
| R. Matthew Neff | Director | Sale of securities on an exchange or to another person at price $ 19.10 per share. | 17 Oct 2022 | 1,000 | 64,388 (0%) | 0% | 19.1 | 19,100 | Common Stock |
| Michael Garrett | Chief Commercial Officer | Purchase of securities on an exchange or from another person at price $ 23.06 per share. | 15 Sep 2022 | 1,000 | 2,000 (0%) | 0% | 23.1 | 23,058 | Common Stock |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 22.34 per share. | 09 Sep 2022 | 8,900 | 51,694 (0%) | 0% | 22.3 | 198,826 | Common Stock |
| Fernanda Beraldi | General Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Apr 2022 | 2,500 | 2,500 | - | - | Employee Stock Option (right to buy) | |
| Richard Allen Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 4,275 | 71,958 (0%) | 0% | 0 | Common Stock | |
| Gregory C. Davis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 4,275 | 41,958 (0%) | 0% | 0 | Common Stock | |
| R. Matthew Neff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 4,275 | 65,388 (0%) | 0% | 0 | Common Stock | |
| Nigel Brown | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 4,275 | 4,715 (0%) | 0% | 0 | Common Stock | |
| Scott Cragg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 4,275 | 4,715 (0%) | 0% | 0 | Common Stock | |
| Fernanda Beraldi | General Counsel & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 2,500 | 2,500 (0%) | 0% | 0 | Common Stock | |
| Robert W. Leasure | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2022 | 74,315 | 359,531 (3%) | 0% | 0 | Common Shares | |
| Robert W. Leasure | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2022 | 275,000 | 634,531 (5%) | 2% | 0 | Common Shares | |
| James Harkness | Chief Operating Officer, RMS | Purchase of securities on an exchange or from another person at price $ 18.84 per share. | 15 Mar 2022 | 4,049 | 38,968 (0%) | 0% | 18.8 | 76,283 | Common Shares |
| James Harkness | Chief Operating Officer, RMS | Purchase of securities on an exchange or from another person at price $ 19.74 per share. | 15 Mar 2022 | 34,919 | 34,919 (0%) | 0% | 19.7 | 689,353 | Common Shares |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Purchase of securities on an exchange or from another person at price $ 23.97 per share. | 22 Feb 2022 | 2,000 | 42,195 (0%) | 0% | 24.0 | 47,946 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Purchase of securities on an exchange or from another person at price $ 23.07 per share. | 18 Feb 2022 | 5,000 | 83,875 (0%) | 0% | 23.1 | 115,358 | Common Shares |
| William D. Pitchford | Chief HR Officer | Purchase of securities on an exchange or from another person at price $ 21.12 per share. | 18 Feb 2022 | 3,500 | 76,174 (0%) | 0% | 21.1 | 73,920 | Common Shares |
| Michael Garrett | Chief Commercial Officer | Purchase of securities on an exchange or from another person at price $ 23.50 per share. | 18 Feb 2022 | 1,000 | 1,000 (0%) | 0% | 23.5 | 23,500 | Common Shares |
| Gregory C. Davis | Director | Purchase of securities on an exchange or from another person at price $ 21.12 per share. | 17 Feb 2022 | 1,250 | 37,683 (0%) | 0% | 21.1 | 26,400 | Common Shares |
| Gregory C. Davis | Director | Purchase of securities on an exchange or from another person at price $ 23.93 per share. | 17 Feb 2022 | 2,500 | 36,433 (0%) | 0% | 23.9 | 59,814 | Common Shares |
| Gregory C. Davis | Director | Purchase of securities on an exchange or from another person at price $ 20.57 per share. | 17 Feb 2022 | 1,250 | 33,933 (0%) | 0% | 20.6 | 25,714 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 23.03 per share. | 17 Feb 2022 | 5,000 | 285,216 (2%) | 0% | 23.0 | 115,131 | Common Shares |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 23.71 per share. | 16 Feb 2022 | 5,800 | 37,194 (0%) | 0% | 23.7 | 137,524 | Common Shares |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 23.88 per share. | 16 Feb 2022 | 1,000 | 42,794 (0%) | 0% | 23.9 | 23,879 | Common Shares |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 21.19 per share. | 16 Feb 2022 | 4,600 | 41,794 (0%) | 0% | 21.2 | 97,468 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 40,000 | 78,875 (0%) | 0% | 0 | Common Shares | |
| William D. Pitchford | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 30,000 | 72,674 (0%) | 0% | 0 | Common Shares | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 30,000 | 678,524 (6%) | 0% | 0 | Common Shares | |
| John E. Sagartz | Director, Chief Strategy Officer | Purchase of securities on an exchange or from another person at price $ 19.95 per share. | 15 Feb 2022 | 2,506 | 681,030 (6%) | 0% | 20.0 | 49,999 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 42,429 | 280,216 (2%) | 0% | 0 | Common Shares | |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Sale of securities on an exchange or to another person at price $ 43.04 per share. | 22 Dec 2021 | 3,057 | 40,195 (0%) | 0% | 43.0 | 131,577 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 214 | 38,875 (0%) | 0% | 0 | Common Shares | |
| William D. Pitchford | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2021 | 299 | 42,674 (0%) | 0% | 0 | Common Shares | |
| Scott Cragg | Director | Other type of transaction at price $ 0.00 per share. | 15 Nov 2021 | 19,951 | 499,095 (4%) | 0% | 0 | Common Shares | |
| Scott Cragg | Director | Other type of transaction at price $ 0.00 per share. | 15 Nov 2021 | 359,033 | 479,144 (4%) | 3% | 0 | Common Shares | |
| Mark Bibi | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 58,134 | 58,134 (0%) | 0% | - | Common Shares | |
| Nigel Brown | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 440 | 440 (0%) | 0% | 0 | Common Shares | |
| Scott Cragg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 120,111 | 120,111 (1%) | 1% | - | Common Shares | |
| Scott Cragg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 440 | 440 (0%) | 0% | 0 | Common Shares | |
| James Harkness | Chief Operating Officer, RMS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 118,593 | 118,593 | - | - | Employee Stock Option (right to buy) | |
| Adrian Hardy | Executive VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 355,780 | 355,780 | - | - | Employee Stock Option (right to buy) | |
| Michael Garrett | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2021 | 67,202 | 67,202 | - | - | Employee Stock Option (right to buy) | |
| Beth A. Taylor | VP- Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Oct 2021 | 1,332 | 38,661 (0%) | 0% | 0 | Common Shares | |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Oct 2021 | 1,087 | 43,252 (0%) | 0% | 0 | Common Shares | |
| William D. Pitchford | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Oct 2021 | 454 | 42,375 (0%) | 0% | 0 | Common Shares | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Oct 2021 | 7,571 | 237,787 (2%) | 0% | 0 | Common Shares | |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Oct 2021 | 954 | 31,394 (0%) | 0% | 0 | Common Shares | |
| John E. Sagartz | Director, Chief Strategy Officer | Purchase of securities on an exchange or from another person at price $ 28.70 per share. | 07 Jun 2021 | 1,742 | 648,524 (5%) | 0% | 28.7 | 49,995 | Common Shares |
| John E. Sagartz | Director, Chief Strategy Officer | Purchase of securities on an exchange or from another person at price $ 24.78 per share. | 27 May 2021 | 2,012 | 646,782 (5%) | 0% | 24.8 | 49,857 | Common Shares |
| John E. Sagartz | Director, Chief Strategy Officer | Purchase of securities on an exchange or from another person at price $ 24.00 per share. | 27 May 2021 | 5 | 644,770 (5%) | 0% | 24 | 120 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Purchase of securities on an exchange or from another person at price $ 23.14 per share. | 13 May 2021 | 2,154 | 37,329 (0%) | 0% | 23.1 | 49,844 | Common Shares |
| William D. Pitchford | Chief HR Officer | Purchase of securities on an exchange or from another person at price $ 23.72 per share. | 13 May 2021 | 1,500 | 41,921 (0%) | 0% | 23.7 | 35,580 | Common Shares |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 22.91 per share. | 13 May 2021 | 5,000 | 30,440 (0%) | 0% | 22.9 | 114,550 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2021 | 880 | 35,175 (0%) | 0% | 0 | Common Shares | |
| William D. Pitchford | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2021 | 880 | 40,421 (0%) | 0% | 0 | Common Shares | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2021 | 880 | 644,765 (5%) | 0% | 0 | Common Shares | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2021 | 3,667 | 230,216 (2%) | 0% | 0 | Common Shares | |
| Joseph Earl Flynn | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2021 | 880 | 128,394 (1%) | 0% | 0 | Common Shares | |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2021 | 440 | 25,440 (0%) | 0% | 0 | Common Shares | |
| Richard Allen Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 2,683 | 42,683 (0%) | 0% | 0 | Common Shares | |
| Gregory C. Davis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 2,683 | 32,683 (0%) | 0% | 0 | Common Shares | |
| R. Matthew Neff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2021 | 2,683 | 61,113 (0%) | 0% | 0 | Common Shares | |
| Beth A. Taylor | VP- Finance & CFO | Purchase of securities on an exchange or from another person at price $ 17.70 per share. | 05 Mar 2021 | 5,000 | 34,295 (0%) | 0% | 17.7 | 88,500 | Common Shares |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 18.60 per share. | 01 Mar 2021 | 1,712 | 25,000 (0%) | 0% | 18.6 | 31,843 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 14.42 per share. | 24 Feb 2021 | 5,000 | 5,000 (0%) | 0% | 14.4 | 72,100 | Common Shares |
| John Gregory Beattie | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 14.00 per share. | 23 Feb 2021 | 8,288 | 23,288 (0%) | 0% | 14 | 116,032 | Common Shares |
| John Gregory Beattie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2021 | 15,000 | 15,000 (0%) | 0% | 0 | Common Shares | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2020 | 40,000 | 226,549 (2%) | 0% | 0 | Common Shares | |
| Beth A. Taylor | VP- Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2020 | 5,995 | 29,295 (0%) | 0% | 0 | Common Shares | |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2020 | 7,964 | 42,165 (0%) | 0% | 0 | Common Shares | |
| William D. Pitchford | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2020 | 7,541 | 39,541 (0%) | 0% | 0 | Common Shares | |
| Michael A. Baim | VP Bioanalytical Services | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2020 | 6,938 | 14,656 (0%) | 0% | 0 | Common Shares | |
| John E. Sagartz | Director, Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2020 | 9,653 | 643,885 (5%) | 0% | 0 | Common Shares | |
| R. Matthew Neff | Director | Purchase of securities on an exchange or from another person at price $ 4.75 per share. | 19 Aug 2020 | 5,000 | 60,350 (0%) | 0% | 4.8 | 23,750 | Common Shares |
| John E. Sagartz | Director, Chief Strategy Officer | Purchase of securities on an exchange or from another person at price $ 4.75 per share. | 19 Aug 2020 | 3,733 | 634,232 (5%) | 0% | 4.8 | 17,732 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 5.20 per share. | 15 Jun 2020 | 2,884 | 186,549 (1%) | 0% | 5.2 | 14,997 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2020 | 10,000 | 23,300 (0%) | 0% | 0 | Common Shares | |
| William D. Pitchford | Chief HR Officer | Purchase of securities on an exchange or from another person at price $ 4.47 per share. | 21 May 2020 | 10,000 | 32,000 (0%) | 0% | 4.5 | 44,700 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Purchase of securities on an exchange or from another person at price $ 4.52 per share. | 19 May 2020 | 3,300 | 13,300 (0%) | 0% | 4.5 | 14,916 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Purchase of securities on an exchange or from another person at price $ 4.38 per share. | 19 May 2020 | 5,067 | 5,067 (0%) | 0% | 4.4 | 22,193 | Common Shares |
| Beth A. Taylor | VP- Finance & CFO | Purchase of securities on an exchange or from another person at price $ 4.42 per share. | 19 May 2020 | 4,933 | 10,000 (0%) | 0% | 4.4 | 21,804 | Common Shares |
| Richard Allen Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2020 | 10,000 | 40,000 (0%) | 0% | 0 | Common Shares | |
| Gregory C. Davis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2020 | 10,000 | 30,000 (0%) | 0% | 0 | Common Shares | |
| R. Matthew Neff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2020 | 10,000 | 55,350 (0%) | 0% | 0 | Common Shares | |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.49 per share. | 16 Mar 2020 | 5,700 | 183,665 (1%) | 0% | 3.5 | 19,893 | Common Shares |
| R. Matthew Neff | Director | Purchase of securities on an exchange or from another person at price $ 3.80 per share. | 12 Mar 2020 | 12,000 | 42,000 (0%) | 0% | 3.8 | 45,600 | Common Shares |
| R. Matthew Neff | Director | Purchase of securities on an exchange or from another person at price $ 3.93 per share. | 12 Mar 2020 | 3,350 | 45,350 (0%) | 0% | 3.9 | 13,166 | Common Shares |
| Richard Allen Johnson | Director | Purchase of securities on an exchange or from another person at price $ 4.63 per share. | 20 Feb 2020 | 20,000 | 30,000 (0%) | 0% | 4.6 | 92,600 | Common Shares |
| R. Matthew Neff | Director | Purchase of securities on an exchange or from another person at price $ 4.60 per share. | 20 Feb 2020 | 9,458 | 30,000 (0%) | 0% | 4.6 | 43,507 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2020 | 45,000 | 45,000 | - | - | Employee Stock Option (right to buy) | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2020 | 13,000 | 177,965 (1%) | 0% | 0 | Common Shares | |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2019 | 8,436 | 34,201 (0%) | 0% | 0 | Common Shares | |
| Jill C. Blumhoff | VP, Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2019 | 7,000 | 8,811 (0%) | 0% | 0 | Common Shares | |
| Michael A. Baim | VP Bioanalytical Services | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2019 | 7,718 | 7,718 (0%) | 0% | 0 | Common Shares | |
| John E. Sagartz | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2019 | 8,974 | 630,499 (5%) | 0% | 0 | Common Shares | |
| Daniel Thomas Oakley | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2019 | 8,974 | 57,520 (0%) | 0% | 0 | Common Shares | |
| Joseph Earl Flynn | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2019 | 2,564 | 127,514 (1%) | 0% | 0 | Common Shares | |
| William D. Pitchford | Chief HR Officer | Purchase of securities on an exchange or from another person at price $ 3.70 per share. | 13 Sep 2019 | 12,000 | 22,000 (0%) | 0% | 3.7 | 44,400 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.72 per share. | 13 Sep 2019 | 26,846 | 164,965 (1%) | 0% | 3.7 | 99,867 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 3.65 per share. | 13 Sep 2019 | 1,000 | 48,546 (0%) | 0% | 3.7 | 3,650 | Common Shares |
| Wendy Perrow | Director | Purchase of securities on an exchange or from another person at price $ 3.62 per share. | 10 Sep 2019 | 10,000 | 10,000 (0%) | 0% | 3.6 | 36,200 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 3.45 per share. | 05 Sep 2019 | 10,500 | 45,546 (0%) | 0% | 3.5 | 36,225 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 3.35 per share. | 05 Sep 2019 | 2,000 | 47,546 (0%) | 0% | 3.4 | 6,700 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.15 per share. | 04 Sep 2019 | 11,500 | 138,119 (1%) | 0% | 3.2 | 36,225 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.69 per share. | 29 Aug 2019 | 5,000 | 36,046 (0%) | 0% | 2.7 | 13,450 | Common Shares |
| William D. Pitchford | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Aug 2019 | 10,000 | 10,000 (0%) | 0% | 0 | Common Shares | |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.77 per share. | 23 Aug 2019 | 2,594 | 31,046 (0%) | 0% | 2.8 | 7,185 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 2.19 per share. | 19 Aug 2019 | 16,000 | 126,619 (1%) | 0% | 2.2 | 35,040 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 1.99 per share. | 14 Jun 2019 | 7,500 | 28,452 (0%) | 0% | 2.0 | 14,925 | Common Shares |
| R. Matthew Neff | Director | Purchase of securities on an exchange or from another person at price $ 1.98 per share. | 13 Jun 2019 | 1,410 | 22,125 (0%) | 0% | 2.0 | 2,792 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.97 per share. | 12 Jun 2019 | 5,000 | 110,619 (1%) | 0% | 2.0 | 9,850 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 2.00 per share. | 12 Jun 2019 | 4 | 105,619 (0%) | 0% | 2 | 8 | Common Shares |
| Jill C. Blumhoff | VP, Finance & CFO | Purchase of securities on an exchange or from another person at price $ 1.98 per share. | 11 Jun 2019 | 500 | 1,811 (0%) | 0% | 2.0 | 990 | Common Shares |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Purchase of securities on an exchange or from another person at price $ 1.96 per share. | 10 Jun 2019 | 5,000 | 25,765 (0%) | 0% | 2.0 | 9,800 | Common Shares |
| W. Robert Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.98 per share. | 07 Jun 2019 | 7,500 | 105,000 (0%) | 0% | 2.0 | 14,864 | Common Stock |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.96 per share. | 06 Jun 2019 | 5,000 | 105,615 (0%) | 0% | 2.0 | 9,800 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.95 per share. | 06 Jun 2019 | 1,000 | 100,615 (0%) | 0% | 2.0 | 1,950 | Common Shares |
| Gregory C. Davis | Director | Purchase of securities on an exchange or from another person at price $ 1.99 per share. | 29 May 2019 | 5,000 | 10,000 (0%) | 0% | 2.0 | 9,950 | Common Shares |
| Gregory C. Davis | Director | Purchase of securities on an exchange or from another person at price $ 1.96 per share. | 29 May 2019 | 5,000 | 15,000 (0%) | 0% | 2.0 | 9,800 | Common Shares |
| Gregory C. Davis | Director | Purchase of securities on an exchange or from another person at price $ 2.00 per share. | 29 May 2019 | 5,000 | 20,000 (0%) | 0% | 2 | 10,000 | Common Shares |
| Joseph Earl Flynn | Chief Commercial Officer | Other type of transaction at price $ 0.00 per share. | 16 Apr 2019 | 124,950 | 124,950 (1%) | 1% | 0 | Common Shares | |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.00 per share. | 15 Mar 2019 | 1 | 20,952 (0%) | 0% | 2 | 2 | Common Shares |
| John E. Sagartz | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.94 per share. | 14 Mar 2019 | 1,400 | 3,900 (0%) | 0% | 1.9 | 2,716 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.94 per share. | 12 Mar 2019 | 6,000 | 99,615 (0%) | 0% | 1.9 | 11,640 | Common Shares |
| R. Matthew Neff | Director | Purchase of securities on an exchange or from another person at price $ 1.75 per share. | 08 Mar 2019 | 5,715 | 20,715 (0%) | 0% | 1.7 | 10,001 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.77 per share. | 08 Mar 2019 | 4,000 | 93,615 (0%) | 0% | 1.8 | 7,080 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 1.75 per share. | 06 Mar 2019 | 10,000 | 20,951 (0%) | 0% | 1.8 | 17,500 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 1.54 per share. | 01 Mar 2019 | 125 | 10,951 (0%) | 0% | 1.5 | 193 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.51 per share. | 28 Feb 2019 | 8,900 | 79,615 (0%) | 0% | 1.5 | 13,439 | Common Shares |
| Robert W. Leasure | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.62 per share. | 28 Feb 2019 | 10,000 | 89,615 (0%) | 0% | 1.6 | 16,200 | Common Shares |
| Daniel Thomas Oakley | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 1.53 per share. | 27 Feb 2019 | 10,826 | 10,826 (0%) | 0% | 1.5 | 16,564 | Common Shares |
| John E. Sagartz | Director, Ten Percent Owner | 19 Feb 2019 | 2,500 | 2,500 (0%) | 0% | 1.4 | 3,575 | Common Shares | |
| Richard Allen Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 25,000 | 25,000 | - | - | Employee Stock Option (right to buy) | |
| Wendy Perrow | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| Jill C. Blumhoff | VP, Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 25,000 | 25,000 | - | - | Employee Stock Option (right to buy) | |
| Gregory C. Davis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| R. Matthew Neff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| Michael A. Baim | VP Bioanalytical Services | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 15,000 | 15,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel Thomas Oakley | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Feb 2019 | 35,000 | 35,000 | - | - | Employee Stock Option (right to buy) | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2019 | 34,615 | 60,715 (0%) | 0% | 0 | Common Shares | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2019 | 10,000 | 70,715 (0%) | 0% | 0 | Common Shares | |
| Robert W. Leasure | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2019 | 55,000 | 55,000 | - | - | Employee Stock Option (right to buy) | |
| Peter T. Kissinger | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.74 per share. | 14 Sep 2018 | 10,000 | 1,033,457 (10%) | 0% | 1.7 | 17,382 | Common Stock |
| Jill C. Blumhoff | VP, Finance & CFO | 13 Sep 2018 | 450 | 1,311 (0%) | 0% | 1.6 | 729 | Common Shares | |
| R. Matthew Neff | None | Purchase of securities on an exchange or from another person at price $ 1.66 per share. | 12 Sep 2018 | 2,500 | 15,000 (0%) | 0% | 1.7 | 4,150 | Common Shares |
| R. Matthew Neff | None | 12 Sep 2018 | 2,500 | 12,500 (0%) | 0% | 1.7 | 4,125 | Common Shares | |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Purchase of securities on an exchange or from another person at price $ 1.67 per share. | 11 Sep 2018 | 5,000 | 20,765 (0%) | 0% | 1.7 | 8,350 | Common Shares |
| Philip A. Downing | Sr. VP, Preclinical Srvcs. | Purchase of securities on an exchange or from another person at price $ 1.46 per share. | 16 Feb 2018 | 5,000 | 15,765 (0%) | 0% | 1.5 | 7,300 | Common Shares |
| Richard Allen Johnson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Oct 2017 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| Philip A. Downing | VP, Preclinical Srvcs. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Oct 2017 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Wendy Perrow | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Oct 2017 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| Jill C. Blumhoff | VP, Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Oct 2017 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Gregory C. Davis | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Oct 2017 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| R. Matthew Neff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Oct 2017 | 10,000 | 10,000 | - | - | Director Stock Option (right to buy) | |
| R. Matthew Neff | None | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 08 Sep 2017 | 5,000 | 10,000 (0%) | 0% | 1.5 | 7,500 | Common Shares |
| Gregory C. Davis | None | Purchase of securities on an exchange or from another person at price $ 1.70 per share. | 18 Aug 2017 | 5,000 | 5,000 (0%) | 0% | 1.7 | 8,500 | Common Shares |
| R. Matthew Neff | None | Purchase of securities on an exchange or from another person at price $ 1.70 per share. | 18 Aug 2017 | 5,000 | 5,000 (0%) | 0% | 1.7 | 8,500 | Common Shares |
| Jill C. Blumhoff | VP, Finance & CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2017 | 200 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jill C. Blumhoff | VP, Finance & CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2017 | 500 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jill C. Blumhoff | VP, Finance & CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.01 per share. | 15 Mar 2017 | 2,000 | 2,000 (0%) | 0% | 1.0 | 2,020 | Common Shares |
| Jill C. Blumhoff | VP, Finance & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.66 per share. | 15 Mar 2017 | 1,217 | 783 (0%) | 0% | 1.7 | 2,020 | Common Shares |
| Jill C. Blumhoff | VP, Finance & CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.40 per share. | 15 Mar 2017 | 500 | 1,283 (0%) | 0% | 1.4 | 700 | Common Shares |
| Jill C. Blumhoff | VP, Finance & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.66 per share. | 15 Mar 2017 | 422 | 861 (0%) | 0% | 1.7 | 701 | Common Shares |
| Philip A. Downing | VP, Preclinical Srvcs. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.01 per share. | 01 Mar 2017 | 10,000 | 17,000 (0%) | 0% | 1.0 | 10,100 | Common Stock |
| Philip A. Downing | VP, Preclinical Srvcs. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2017 | 10,000 | 0 | - | - | Employee Stock Option (right to buy) | |
| Philip A. Downing | VP, Preclinical Srvcs. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.62 per share. | 01 Mar 2017 | 6,235 | 10,765 (0%) | 0% | 1.6 | 10,101 | Common Stock |
| Connie Leigh Dougherty | VP, Business Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 May 2016 | 423 | 9,074 | - | - | Common Stock | |
| Connie Leigh Dougherty | VP, Business Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 May 2016 | 96 | 8,651 | - | - | Common Stock | |
| Connie Leigh Dougherty | VP, Business Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 May 2016 | 1,655 | 8,555 | - | - | Common Stock | |
| Jill C. Blumhoff | VP, Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2016 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| Jacqueline M. Lemke | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Feb 2016 | 6,000 | 9,000 | - | - | Common Shares | |
| Jacqueline M. Lemke | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Feb 2016 | 4,000 | 60,685 | - | - | Common Shares | |
| Philip A. Downing | VP, Preclinical Srvcs. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Sep 2015 | 3,000 | 7,000 | - | - | Common Stock | |
| Connie Leigh Dougherty | VP, Business Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Aug 2015 | 6,900 | 6,900 | - | - | Common Stock | |
| Jacqueline M. Lemke | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2015 | 500 | 153,500 | - | - | Common Shares | |
| Jacqueline M. Lemke | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2015 | 125,000 | 153,000 | - | - | Common Shares | |
| Jacqueline M. Lemke | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2015 | 500 | 0 | - | - | Option to Purchase Common Shares | |
| Jacqueline M. Lemke | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2015 | 125,000 | 0 | - | - | Non-Qualified Option to Purchase Common Shares | |
| Jacqueline M. Lemke | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 18 Jun 2015 | 96,815 | 56,685 | - | - | Common Stock | |
| Philip A. Downing | VP, Preclinical Srvcs. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| Jacqueline M. Lemke | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Feb 2015 | 7,000 | 28,000 | - | - | Common Shares | |
| Jacqueline M. Lemke | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Feb 2015 | 3,000 | 3,000 | - | - | Common Shares | |
| Connie Leigh Dougherty | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Sep 2014 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| John P. Devine | VP--Toxicology | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Aug 2014 | 2,500 | 2,500 | - | - | Option to Purchase Common Shares | |
| John P. Devine | VP--Toxicology | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Aug 2014 | 2,500 | 2,500 | - | - | Common Stock | |
| Jeffrey Potrzebowski | VP, Finance & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2014 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| James Sevall Bourdage | VP, Bioanalytical Services | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jun 2014 | 10,000 | 10,000 | - | - | Employee Stock Option (right to buy) | |
| John P. Devine | VP--Toxicology | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 03 Mar 2014 | 3,130 | 0 | - | - | Common Stock | |
| John P. Devine | VP--Toxicology | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2013 | 500 | 500 | - | - | Option to Purchase Common Shares | |
| Lori Payne | VP-Bioanalytical Services | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2013 | 500 | 500 | - | - | Option to Purchase Common Shares | |
| Jacqueline M. Lemke | Intrm Pres & CEO, CFO & VP Fin | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2013 | 500 | 500 | - | - | Option to Purchase Common Shares | |
| Jacqueline M. Lemke | Intrm Pres & CEO, CFO & VP Fin | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Oct 2012 | 50,000 | 50,000 | - | - | Option to Purchase Common Shares | |
| David L. Omachinski | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2012 | 10,000 | 20,000 | - | - | Common Shares | |
| David W. Crabb | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2012 | 10,000 | 11,300 | - | - | Common Shares | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2012 | 11,500 | 15,000 | - | - | Common Shares | |
| John B. Landis | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2012 | 30,000 | 30,000 | - | - | Common Shares | |
| A. Charlene Sullivan | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2012 | 10,000 | 10,000 | - | - | Common Shares | |
| Jacqueline M. Lemke | Intrm Pres & CEO, CFO & VP Fin | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2012 | 20,000 | 21,000 | - | - | Common Shares | |
| Richard Allen Johnson | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2012 | 10,000 | 10,000 | - | - | Common Shares | |
| John B. Landis | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jul 2012 | 15,000 | 15,000 | - | - | Option to purchase common shares | |
| Richard Allen Johnson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jul 2012 | 15,000 | 15,000 | - | - | Option to purchase common shares | |
| Anthony S. Chilton | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Apr 2012 | 25,000 | 25,000 | - | - | Option to purchase common shares | |
| Lori Payne | VP Bioanalytical Services | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Apr 2012 | 20,000 | 20,000 | - | - | Option to purchase common shares | |
| Jacqueline M. Lemke | CFO & Vice President--Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Apr 2012 | 125,000 | 125,000 | - | - | Non-Qualified Option to Purchase Common Shares | |
| Anthony S. Chilton | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Feb 2011 | 25,000 | 25,000 | - | - | Option to purchase common shares | |
| David L. Omachinski | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Sep 2010 | 10,000 | 10,000 | - | - | Common Stock | |
| Alberto Hidalgo | VP, Bus. Development & Mrkting | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2010 | 30,000 | 30,000 | - | - | Option to purchase common shares | |
| David L. Omachinski | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2010 | 10,000 | 10,000 | - | - | Option to purchase common shares | |
| Leslie B. Daniels | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2010 | 5,000 | 15,000 | - | - | Option to purchase common shares | |
| Larry S. Boulet | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2010 | 5,000 | 15,000 | - | - | Option to purchase common shares | |
| John B. Landis | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2010 | 10,000 | 10,000 | - | - | Option to purchase common shares | |
| A. Charlene Sullivan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2010 | 10,000 | 10,000 | - | - | Option to purchase common shares | |
| Anthony S. Chilton | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2010 | 125,000 | 125,000 | - | - | Option to purchase common shares | |
| Lina L. Reeves-Kerner | V.P. Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Apr 2010 | 20,000 | 20,000 | - | - | Option to Buy Common Shares | |
| Craig S. Bruntlett | Senior V P, Sales Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Apr 2010 | 20,000 | 20,000 | - | - | Option to Buy Common Shares | |
| Michael R. Cox | VP Finance & Administration | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Apr 2010 | 20,000 | 20,000 | - | - | Option to Buy Common Shares | |
| Kathleen Hodges | Vice President of Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Apr 2010 | 20,000 | 20,000 | - | - | Option to Buy Common Shares | |
| David W. Crabb | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Feb 2010 | 1,300 | 1,300 | - | - | Common Stock | |
| Anthony S. Chilton | COO, Scientific Services | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2010 | 25,000 | 25,000 | - | - | Option to purchase common shares | |
| Michael R. Cox | VP Finance & Administration | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Aug 2009 | 500 | 500 | - | - | Common Stock | |
| Michael R. Cox | VP Finance & Administration | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Aug 2009 | 400 | 900 | - | - | Common Stock | |
| Michael R. Cox | VP Finance & Administration | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Aug 2009 | 100 | 1,000 | - | - | Common Stock | |
| Anthony S. Chilton | COO, Scientific Studies | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2008 | 30,000 | 30,000 | - | - | Employee Stock Option (Right to Buy) | |
| Jon Brewer | VP Sales/Marketing | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2008 | 30,000 | 30,000 | - | - | Employee Stock Option (Right to Buy) | |
| Lina L. Reeves-Kerner | V.P. Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Sep 2008 | 5,000 | 5,000 | - | - | Employee Stock Option (Right to Buy) | |
| William E. Baitinger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Sep 2008 | 12,000 | 12,000 | - | - | Employee Stock Option (Right to Buy) | |
| Leslie B. Daniels | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 04 Sep 2008 | 10,000 | 10,000 | - | - | Employee Stock Option (Right to Buy) | |
| Larry S. Boulet | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Sep 2008 | 10,000 | 10,000 | - | - | Employee Stock Option (Right to Buy) | |
| Richard M. Shepperd | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Mar 2008 | 275,000 | 275,000 | - | - | Employee Stock Option (Right to Buy) | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Mar 2008 | 100 | 1,023,957 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Mar 2008 | 100 | 1,023,857 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Mar 2008 | 200 | 1,023,657 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Mar 2008 | 200 | 1,024,057 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Mar 2008 | 100 | 1,024,257 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Mar 2008 | 600 | 1,024,857 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Mar 2008 | 500 | 1,024,357 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Feb 2008 | 100 | 1,026,057 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Feb 2008 | 100 | 1,025,957 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Feb 2008 | 500 | 1,025,457 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Feb 2008 | 300 | 1,026,557 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Feb 2008 | 100 | 1,026,457 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Feb 2008 | 100 | 1,026,357 | - | - | Common Stock | |
| Peter T. Kissinger | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Feb 2008 | 200 | 1,026,157 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 27 Feb 2008 | 675 | 49,807 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 27 Feb 2008 | 2,325 | 47,482 | - | - | Common Stock | |
| Richard M. Shepperd | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Feb 2008 | 5,000 | 15,750 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 26 Feb 2008 | 100 | 50,682 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 26 Feb 2008 | 100 | 50,582 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 26 Feb 2008 | 100 | 50,482 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 26 Feb 2008 | 1,700 | 50,782 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 22 Feb 2008 | 4,900 | 52,582 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 22 Feb 2008 | 100 | 52,482 | - | - | Common Stock | |
| Ronald E. Shoup | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2007 | 3,000 | 91,316 | - | - | Common Stock | |
| Ronald E. Shoup | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 13 Dec 2007 | 1,395 | 89,921 | - | - | Common Stock | |
| Ronald E. Shoup | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2007 | 3,000 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Ronald E. Shoup | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2007 | 4,000 | 91,715 | - | - | Common Stock | |
| Ronald E. Shoup | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 23 Nov 2007 | 3,850 | 87,865 | - | - | Common Stock | |
| Ronald E. Shoup | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2007 | 4,000 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Lina L. Reeves-Kerner | V.P. Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2007 | 1,000 | 1,614 | - | - | Common Stock | |
| Lina L. Reeves-Kerner | V.P. Human Resources | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 19 Nov 2007 | 931 | 683 | - | - | Common Stock | |
| Lina L. Reeves-Kerner | V.P. Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2007 | 1,000 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Craig S. Bruntlett | Senior V P, Sales Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2007 | 2,000 | 59,344 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 19 Nov 2007 | 1,862 | 57,482 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P, Sales Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2007 | 2,000 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Emilio Cordova | V.P. of Business Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2007 | 500 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Emilio Cordova | V.P. of Business Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2007 | 500 | 500 | - | - | Common Stock | |
| Emilio Cordova | V.P. of Business Development | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 19 Nov 2007 | 466 | 34 | - | - | Common Stock | |
| Michael R. Cox | VP Finance & Administration | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Nov 2007 | 30,000 | 30,000 | - | - | Employee Stock Option (Right to Buy) | |
| Edward M. Chait | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Nov 2007 | 30,000 | 30,000 | - | - | Employee Stock Option (Right to Buy) | |
| Craig S. Bruntlett | Senior V P, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 11 Sep 2007 | 355 | 57,344 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior VP, Sales Development | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 27 Aug 2007 | 100 | 57,699 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 100 | 100 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 200 | 300 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 227 | 527 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 400 | 927 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 236 | 1,163 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 298 | 1,461 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 739 | 2,200 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 1,000 | 3,200 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 100 | 3,300 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 100 | 3,400 | - | - | Common Stock | |
| Larry S. Boulet | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2007 | 100 | 3,500 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 1,000 | 1,750 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 1,000 | 2,750 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 1,000 | 3,750 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 1,000 | 4,750 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 1,079 | 5,829 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 400 | 6,229 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 300 | 6,529 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 300 | 6,829 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 1,400 | 8,229 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 521 | 8,750 | - | - | Common Stock | |
| Richard M. Shepperd | President & Chief Exec. Off. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Feb 2007 | 2,000 | 10,750 | - | - | Common Stock | |
| Ronald E. Shoup | Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Dec 2006 | 602 | 87,915 | - | - | Common Stock | |
| Ronald E. Shoup | Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Dec 2006 | 200 | 87,715 | - | - | Common Stock | |
| William E. Baitinger | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Jun 2006 | 400 | 90,445 | - | - | Common Stock | |
| William E. Baitinger | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Jun 2006 | 188 | 90,257 | - | - | Common Stock | |
| William E. Baitinger | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Jun 2006 | 212 | 90,045 | - | - | Common Stock | |
| Ronald E. Shoup | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Jun 2006 | 5,000 | 89,339 | - | - | Common Stock | |
| Ronald E. Shoup | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Jun 2006 | 260 | 89,079 | - | - | Common Stock | |
| Ronald E. Shoup | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Jun 2006 | 111 | 88,968 | - | - | Common Stock | |
| William E. Baitinger | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Jun 2006 | 400 | 90,845 | - | - | Common Stock | |
| William E. Baitinger | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 05 Jun 2006 | 300 | 91,245 | - | - | Common Stock | |
| Ronald E. Shoup | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 31 May 2006 | 5,000 | 95,739 | - | - | Common Stock | |
| Ronald E. Shoup | Director, Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 31 May 2006 | 1,400 | 94,339 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 31 May 2006 | 5,000 | 52,799 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 200 | 62,599 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 100 | 62,499 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 2,053 | 60,446 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 100 | 60,346 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 400 | 59,946 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 99 | 59,847 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 99 | 59,748 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 50 | 59,698 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 300 | 59,398 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 99 | 59,299 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 100 | 59,199 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 100 | 59,099 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 1,200 | 57,899 | - | - | Common Stock | |
| Craig S. Bruntlett | Senior V P International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 May 2006 | 100 | 57,799 | - | - | Common Stock | |
| Edward M. Chait | Executive Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2005 | 25,000 | 25,000 | - | - | Employee Stock Option (Right to Buy) | |
| Edward M. Chait | Executive Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2005 | 25,000 | 25,000 | - | - | Employee Stock Option (Right to Buy) | |
| Gayl W. Doster | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Aug 2004 | 5,000 | 5,000 | - | - | Option to Purchase Common Shares | |
| Craig S. Bruntlett | Sr. VP-International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 09 Jun 2004 | 2,000 | 62,799 | - | - | Common Stock | |
| Craig S. Bruntlett | Sr. VP-International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 09 Jun 2004 | 4,000 | 62,799 | - | - | Common Stock | |
| Craig S. Bruntlett | Sr. VP-International Sales | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 09 Jun 2004 | 4,000 | 62,799 | - | - | Common Stock | |
| Michael R. Cox | V.P. Finance, CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2004 | 25,000 | 25,000 | - | - | Option to Buy Common Shares | |
| Michael R. Cox | V.P. Finance, CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2004 | 25,000 | 25,000 | - | - | Option to Buy Common Shares | |
| Candice B. Kissinger | Director, Vice President, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 30,000 | 30,000 | - | - | Option to Buy Common Shares | |
| Lina L. Reeves-Kerner | V.P. - Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 17,000 | 17,000 | - | - | Option to Buy Common Shares | |
| Ronald E. Shoup | Director, Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 40,000 | 40,000 | - | - | Option to Buy Common Shares | |
| Craig S. Bruntlett | Sr. V.P. International Sales | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 17,000 | 17,000 | - | - | Option to Buy Common Shares | |
| David W. Crabb | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 5,000 | 5,000 | - | - | Option to Buy Common Shares | |
| Henningsen Gerry | Director BAS Evansville | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 20,000 | 20,000 | - | - | Option to Buy Common Shares | |
| Mcclure B Margaret | Dir, Pharmaceutical Lab. Div. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 10,000 | 10,000 | - | - | Option to Buy Common Shares | |
| Noone S Michael | Dir. of Clinical Affairs, Balt | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 20,000 | 20,000 | - | - | Option to Buy Common Shares | |
| Sawyers William | Laboratory Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2004 | 10,000 | 10,000 | - | - | Option to Buy Common Shares | |
| Leslie B. Daniels | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Dec 2003 | 38,042 | 38,042 | - | - | Common Stock |