239.1K XNAS Volume
XNAS 19 May, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Sean Smith | Interim CFO, Prin Acct Off | Sale of securities on an exchange or to another person at price $ 0.62 per share. | 10 Aug 2023 | 1,323 | 21,637 (0%) | 0% | 0.6 | 818 | Common Stock |
| Sean Smith | Interim CFO, Prin Acct Off | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2023 | 5,000 | 22,960 (0%) | 0% | 0 | Common Stock | |
| Sean Smith | Interim CFO, Prin Acct Off | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2023 | 5,000 | 0 | - | - | Restricted Stock Units | |
| Martin Babler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Rohan Palekar | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Sarah B. Noonberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Erin M. Lavelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Priti Patel | Former Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2023 | 10,000 | 0 | - | - | Restricted Stock Units | |
| Priti Patel | Former Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2023 | 10,000 | 41,082 (0%) | 0% | 0 | Common Stock | |
| Priti Patel | Former Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 0.69 per share. | 31 Mar 2023 | 3,769 | 37,313 (0%) | 0% | 0.7 | 2,608 | Common Stock |
| Priti Patel | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2023 | 35,000 | 35,000 | - | - | Restricted Stock Units | |
| Priti Patel | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 0.60 per share. | 01 Feb 2023 | 14,380 | 31,082 (0%) | 0% | 0.6 | 8,588 | Common Stock |
| Priti Patel | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2023 | 35,000 | 45,462 (0%) | 0% | 0 | Common Stock | |
| Sean Smith | Principal Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2023 | 12,500 | 19,276 (0%) | 0% | 0 | Common Stock | |
| Sean Smith | Principal Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2023 | 12,500 | 12,500 | - | - | Restricted Stock Units | |
| Sean Smith | Principal Accounting Officer | Sale of securities on an exchange or to another person at price $ 0.60 per share. | 01 Feb 2023 | 3,316 | 15,960 (0%) | 0% | 0.6 | 1,980 | Common Stock |
| Jonathan G. Drachman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Aug 2022 | 350,000 | 350,000 | - | - | Stock Option (Right to Buy) | |
| Carl Walkey | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Aug 2022 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Priti Patel | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Aug 2022 | 250,000 | 250,000 | - | - | Stock Option (Right to Buy) | |
| Sean Smith | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Aug 2022 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Donna Cochener | General Counsel, SVP Legal | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Aug 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Martin Babler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2022 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Rohan Palekar | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2022 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2022 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Sarah B. Noonberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2022 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Erin M. Lavelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 May 2022 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Priti Patel | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2022 | 10,000 | 12,000 (0%) | 0% | 0 | Common Stock | |
| Priti Patel | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.22 per share. | 30 Apr 2022 | 5,538 | 6,462 (0%) | 0% | 1.2 | 6,749 | Common Stock |
| Priti Patel | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2022 | 10,000 | 10,000 | - | - | Restricted Stock Units | |
| Donna Cochener | General Counsel, SVP Legal | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 400,000 | 400,000 | - | - | Stock Option (Right to Buy) | |
| Rohan Palekar | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2022 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Sean Smith | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Mar 2022 | 80,000 | 80,000 | - | - | Stock Option (Right to Buy) | |
| Carl Walkey | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2022 | 55,000 | 55,000 | - | - | Restricted Stock Units | |
| Robert Ho | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2022 | 70,000 | 70,000 | - | - | Restricted Stock Units | |
| Priti Patel | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2022 | 70,000 | 70,000 | - | - | Restricted Stock Units | |
| Jonathan G. Drachman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 6.45 per share. | 24 Aug 2021 | 25,000 | 25,000 (0%) | 0% | 6.4 | 161,225 | Common Stock |
| Jonathan G. Drachman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 6.45 per share. | 24 Aug 2021 | 25,000 | 25,000 (0%) | 0% | 6.4 | 161,225 | Common Stock |
| Jonathan G. Drachman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 6.11 per share. | 24 Aug 2021 | 100,000 | 2,348,686 (4%) | 0% | 6.1 | 611,100 | Common Stock |
| Jonathan G. Drachman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 400,000 | 400,000 | - | - | Stock Option (Right to Buy) | |
| Carl Walkey | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Robert Ho | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 190,000 | 190,000 | - | - | Stock Option (Right to Buy) | |
| Holly Vance | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Priti Patel | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2021 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 10.19 per share. | 16 Jun 2021 | 600 | 1,352,489 (2%) | 0% | 10.2 | 6,114 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 10.82 per share. | 09 Jun 2021 | 650 | 1,353,089 (2%) | 0% | 10.8 | 7,036 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.00 per share. | 08 Jun 2021 | 600 | 1,353,739 (2%) | 0% | 11 | 6,600 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 10.00 per share. | 04 Jun 2021 | 600 | 1,354,339 (2%) | 0% | 10 | 6,000 | Common Stock |
| Jonathan G. Drachman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 9.61 per share. | 03 Jun 2021 | 10,000 | 2,248,686 (4%) | 0% | 9.6 | 96,082 | Common Stock |
| Jonathan G. Drachman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 9.48 per share. | 03 Jun 2021 | 40,000 | 2,238,686 (4%) | 0% | 9.5 | 379,272 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 10.00 per share. | 26 May 2021 | 600 | 1,354,939 (2%) | 0% | 10 | 6,000 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 10.63 per share. | 19 May 2021 | 600 | 1,355,539 (2%) | 0% | 10.6 | 6,378 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.09 per share. | 12 May 2021 | 1,200 | 1,354,762 (2%) | 0% | 11.1 | 13,308 | Common Stock |
| Martin Babler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 May 2021 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 May 2021 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Lewis T. Williams | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 May 2021 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Sarah B. Noonberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 May 2021 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Erin M. Lavelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 May 2021 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.30 per share. | 05 May 2021 | 1,200 | 1,355,962 (2%) | 0% | 11.3 | 13,560 | Common Stock |
| Priti Patel | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 20,000 | 20,000 | - | - | Restricted Stock Units | |
| Priti Patel | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Apr 2021 | 475,000 | 475,000 | - | - | Stock Option (Right to Buy) | |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 12.58 per share. | 28 Apr 2021 | 2,400 | 1,357,162 (2%) | 0% | 12.6 | 30,192 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 26 Apr 2021 | 600 | 1,359,562 (2%) | 0% | 13 | 7,800 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.98 per share. | 21 Apr 2021 | 1,800 | 1,360,162 (2%) | 0% | 12.0 | 21,564 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 12.22 per share. | 14 Apr 2021 | 1,800 | 1,361,962 (2%) | 0% | 12.2 | 21,996 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 12.02 per share. | 07 Apr 2021 | 1,800 | 1,363,762 (2%) | 0% | 12.0 | 21,636 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 05 Apr 2021 | 600 | 1,365,562 (2%) | 0% | 13 | 7,800 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.96 per share. | 31 Mar 2021 | 1,800 | 1,366,162 (2%) | 0% | 12.0 | 21,528 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.95 per share. | 22 Mar 2021 | 1,800 | 1,367,962 (2%) | 0% | 12.0 | 21,516 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 12.00 per share. | 22 Mar 2021 | 600 | 1,369,762 (2%) | 0% | 12 | 7,200 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.36 per share. | 17 Mar 2021 | 1,200 | 1,370,362 (2%) | 0% | 11.4 | 13,632 | Common Stock |
| Robert Ho | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Mar 2021 | 25,000 | 28,000 (0%) | 0% | 0 | Common Stock | |
| Robert Ho | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Mar 2021 | 25,000 | 50,000 | - | - | Restricted Stock Units | |
| Robert Ho | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 11.01 per share. | 16 Mar 2021 | 6,497 | 21,503 (0%) | 0% | 11.0 | 71,556 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.97 per share. | 10 Mar 2021 | 1,800 | 1,371,562 (2%) | 0% | 12.0 | 21,540 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 11.87 per share. | 03 Mar 2021 | 1,800 | 1,373,362 (2%) | 0% | 11.9 | 21,360 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 24 Feb 2021 | 600 | 1,375,162 (2%) | 0% | 13 | 7,800 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 12.14 per share. | 24 Feb 2021 | 1,800 | 1,375,762 (2%) | 0% | 12.1 | 21,852 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 12.70 per share. | 17 Feb 2021 | 2,400 | 1,377,562 (2%) | 0% | 12.7 | 30,480 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 14.20 per share. | 10 Feb 2021 | 3,000 | 1,379,962 (2%) | 0% | 14.2 | 42,600 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 14.00 per share. | 05 Feb 2021 | 600 | 1,382,962 (2%) | 0% | 14 | 8,400 | Common Stock |
| Carl Walkey | Senior Vice President | Sale of securities on an exchange or to another person at price $ 13.23 per share. | 03 Feb 2021 | 2,400 | 1,383,562 (2%) | 0% | 13.2 | 31,752 | Common Stock |
| Carl Walkey | Senior Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2021 | 45,000 | 45,000 | - | - | Stock Option (Right to Buy) | |
| Holly Vance | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Oct 2020 | 220,000 | 220,000 | - | - | Stock Option (Right to Buy) | |
| Martin Babler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Sep 2020 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Jonathan G. Drachman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2020 | 420,000 | 420,000 | - | - | Stock Option (Right to Buy) | |
| Robert Ho | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2020 | 90,000 | 90,000 | - | - | Stock Option (Right to Buy) | |
| Erin Lavelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2020 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Lewis T. Williams | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Sean P. Nolan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Sarah B. Noonberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2020 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Robert Ho | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Mar 2020 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Robert Ho | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Mar 2020 | 75,000 | 75,000 | - | - | Restricted Stock Units | |
| Jonathan G. Drachman | Director, President and CEO | 12 Nov 2019 | 12,616 | 0 (0%) | 0% | 0 | Series A Preferred Stock | ||
| Jonathan G. Drachman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 8.40 per share. | 12 Nov 2019 | 119,047 | 2,198,686 (4%) | 0% | 8.4 | 999,995 | Common Stock |
| Jonathan G. Drachman | Director, President and CEO | 12 Nov 2019 | 1,261,600 | 2,079,639 (5%) | 3% | 0 | Common Stock | ||
| Todd E. Simpson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2019 | 22,000 | 22,000 | - | - | Stock Option (right to buy) | |
| Lewis T. Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2019 | 22,000 | 22,000 | - | - | Stock Option (right to buy) | |
| Sean P. Nolan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2019 | 22,000 | 22,000 | - | - | Stock Option (right to buy) | |
| Sarah B. Noonberg | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2019 | 22,000 | 22,000 | - | - | Stock Option (right to buy) | |
| Jonathan G. Drachman | Director, See Remarks | Purchase of securities on an exchange or from another person at price $ 2.85 per share. | 09 Sep 2019 | 76,822 | 411,250 (1%) | 0% | 2.8 | 218,559 | Common Stock |
| Jonathan G. Drachman | Director, See Remarks | Purchase of securities on an exchange or from another person at price $ 3.30 per share. | 09 Sep 2019 | 136,436 | 584,428 (2%) | 0% | 3.3 | 449,898 | Common Stock |
| Jonathan G. Drachman | Director, See Remarks | Purchase of securities on an exchange or from another person at price $ 3.08 per share. | 09 Sep 2019 | 36,742 | 447,992 (1%) | 0% | 3.1 | 113,290 | Common Stock |
| Jonathan G. Drachman | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Aug 2019 | 1,650,000 | 1,650,000 | - | - | Stock Option (Right to Buy) | |
| Jonathan G. Drachman | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2019 | 12,616 | 12,616 (0%) | 0% | 0 | Series A Preferred Stock | |
| Jonathan G. Drachman | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2019 | 568,039 | 568,039 (2%) | 2% | 0 | Common Stock | |
| David J. Main | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Aug 2018 | 415,000 | 415,000 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Aug 2018 | 195,000 | 195,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Aug 2018 | 145,000 | 145,000 | - | - | Stock Option (Right to Buy) | |
| Shelley McCloskey | VP, HR and Administration | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Aug 2018 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Daniel J. Levitt | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2018 | 3,906 | 0 | - | - | Stock Option (Right to Buy) | |
| Daniel J. Levitt | None | Sale of securities on an exchange or to another person at price $ 12.67 per share. | 14 May 2018 | 3,906 | 0 (0%) | 0% | 12.7 | 49,489 | Common Stock |
| Daniel J. Levitt | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.56 per share. | 14 May 2018 | 3,906 | 3,906 (0%) | 0% | 10.6 | 41,247 | Common Stock |
| Daniel J. Levitt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Robert E. Pelzer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Sean P. Nolan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Gary J. Bridger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 May 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.56 per share. | 15 Mar 2018 | 1,302 | 1,302 (0%) | 0% | 10.6 | 13,749 | Common Stock |
| Lloyd Mackenzie | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2018 | 1,302 | 0 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 14.63 per share. | 15 Mar 2018 | 1,302 | 0 (0%) | 0% | 14.6 | 19,049 | Common Stock |
| David J. Main | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2018 | 225,000 | 225,000 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2018 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2018 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Troupin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2018 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Shelley McCloskey | VP, HR and Administration | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2018 | 45,000 | 45,000 | - | - | Stock Option (Right to Buy) | |
| Abigail Jenkins | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2018 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| David J. Main | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2017 | 6,000 | 3,625 | - | - | Stock Option (Right to Buy( | |
| David J. Main | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 13.16 per share. | 01 Jun 2017 | 3,625 | 71,530 (0%) | 0% | 13.2 | 47,696 | Common Stock |
| David J. Main | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.60 per share. | 01 Jun 2017 | 3,625 | 75,155 (0%) | 0% | 9.6 | 34,800 | Common Stock |
| David J. Main | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 13.59 per share. | 01 Jun 2017 | 6,000 | 71,530 (0%) | 0% | 13.6 | 81,560 | Common Stock |
| David J. Main | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.60 per share. | 01 Jun 2017 | 6,000 | 77,530 (0%) | 0% | 9.6 | 57,600 | Common Stock |
| David J. Main | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 01 Jun 2017 | 6,000 | 71,530 (0%) | 0% | 13.0 | 77,988 | Common Stock |
| David J. Main | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.60 per share. | 01 Jun 2017 | 6,000 | 77,530 (0%) | 0% | 9.6 | 57,600 | Common Stock |
| David J. Main | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2017 | 3,625 | 0 | - | - | Stock Option (Right to Buy) | |
| David J. Main | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2017 | 6,000 | 9,625 | - | - | Stock Option (Right to Buy) | |
| Daniel J. Levitt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2017 | 9,000 | 9,000 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2017 | 9,000 | 9,000 | - | - | Stock Option (Right to Buy) | |
| Robert E. Pelzer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2017 | 9,000 | 9,000 | - | - | Stock Option (Right to Buy) | |
| Sean P. Nolan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2017 | 9,000 | 9,000 | - | - | Stock Option (Right to Buy) | |
| Gary J. Bridger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2017 | 9,000 | 9,000 | - | - | Stock Option (Right to Buy) | |
| David J. Main | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 185,000 | 185,000 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 80,000 | 80,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | VP Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Barbara Troupin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| David Chilton Mitchell | VP Global Regulatory & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Shelley McCloskey | VP, HR and Administration | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Abigail Jenkins | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Mar 2017 | 80,000 | 80,000 | - | - | Stock Option (Right to Buy) | |
| Shelley McCloskey | VP, HR and Administration | 31 Dec 2016 | 35,000 | 35,000 | - | - | Stock Option (Right to Buy) | ||
| Barbara Troupin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Nov 2016 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Sep 2016 | 294,707 | 1,119,075 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Sep 2016 | 2,476,348 | 9,404,467 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Sep 2016 | 12,550 | 1,131,625 | - | - | Common Stock | |
| Abigail Jenkins | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2016 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Daniel J. Levitt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 May 2016 | 7,500 | 7,500 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 May 2016 | 7,500 | 7,500 | - | - | Stock Option (Right to Buy) | |
| Robert E. Pelzer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 May 2016 | 7,500 | 7,500 | - | - | Stock Option (Right to Buy) | |
| Sean P. Nolan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 May 2016 | 7,500 | 7,500 | - | - | Stock Option (Right to Buy) | |
| Gary Bridger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 May 2016 | 7,500 | 7,500 | - | - | Stock Option (Right to Buy) | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 3,374 | 781,421 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 30,986 | 6,533,759 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 7,420 | 788,841 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 68,132 | 6,601,891 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 1,289 | 790,130 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 11,840 | 6,613,731 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 20,192 | 810,322 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 185,413 | 6,799,144 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 14,046 | 824,368 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 128,975 | 6,928,119 | - | - | Common Stock | |
| Stephen B. Shrewsbury | CMO; Senior VP Clinical Dev. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2016 | 35,000 | 35,000 | - | - | Stock Option (Right to Buy) | |
| David J. Main | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2016 | 120,000 | 120,000 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2016 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | VP Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2016 | 35,000 | 35,000 | - | - | Stock Option (Right to Buy) | |
| David Chilton Mitchell | VP Global Regulatory & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2016 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 1,887 | 765,980 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 17,221 | 6,393,162 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 440 | 766,420 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 4,021 | 6,397,183 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 17 | 766,437 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 156 | 6,397,339 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 2,810 | 769,247 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 25,650 | 6,422,989 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 312 | 769,559 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 2,833 | 6,425,822 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 497 | 770,056 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 4,503 | 6,430,325 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 278 | 770,334 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 2,522 | 6,432,847 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 7,318 | 777,652 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 66,345 | 6,499,192 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 395 | 778,047 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jan 2016 | 3,581 | 6,502,773 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 5,029 | 750,354 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 45,903 | 6,250,533 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 1,109 | 751,463 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 10,123 | 6,260,656 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 1,568 | 753,031 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 14,313 | 6,274,969 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 6,294 | 759,325 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 57,453 | 6,332,422 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 1,511 | 760,836 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 13,789 | 6,346,211 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 3,067 | 763,903 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 27,996 | 6,374,207 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 190 | 764,093 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Jan 2016 | 1,734 | 6,375,941 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 9,970 | 735,198 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 90,550 | 6,112,654 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 1,399 | 736,597 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 12,706 | 6,125,360 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 330 | 736,927 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 2,998 | 6,128,358 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 2,296 | 739,223 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 20,851 | 6,149,209 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 361 | 739,584 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 3,279 | 6,152,488 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 545 | 740,129 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 4,949 | 6,157,437 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 5,196 | 745,325 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jan 2016 | 47,193 | 6,204,630 | - | - | Common Stock | |
| Gary Bridger | None | Other type of transaction at price $ 0.00 per share. | 31 Oct 2015 | 1,543,989 | 0 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Sep 2015 | 266,563 | 725,228 | - | - | Common Stock | |
| Julian C. Baker | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Sep 2015 | 2,213,469 | 6,022,104 | - | - | Common Stock | |
| David Chilton Mitchell | VP Global Regulatory & Quality | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Aug 2015 | 3,575 | 3,575 | - | - | Common Stock | |
| Kamran Alam | CFO, Vice President Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 8,246 | 2,170 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 20,833 | 0 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 8,246 | 8,246 | - | - | Common Stock | |
| Kamran Alam | CFO, Vice President Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 20,833 | 29,079 | - | - | Common Stock | |
| Kamran Alam | CFO, Vice President Finance | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 12 Aug 2015 | 29,079 | 0 | - | - | Common Stock | |
| Lloyd Mackenzie | VP Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 7,812 | 0 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | VP Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 28,075 | 1,872 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | VP Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 7,812 | 7,812 | - | - | Common Stock | |
| Lloyd Mackenzie | VP Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2015 | 28,075 | 35,887 | - | - | Common Stock | |
| Lloyd Mackenzie | VP Technical Operations | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 12 Aug 2015 | 35,887 | 0 | - | - | Common Stock | |
| David Chilton Mitchell | VP Global Regulatory & Quality | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 Aug 2015 | 1,600 | 1,600 | - | - | Common Stock | |
| Daniel J. Levitt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| Robert E. Pelzer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| Stephen B. Shrewsbury | CMO; Senior VP Clinical Dev. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Sean P. Nolan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| David J. Main | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 65,000 | 65,000 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | VP Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Gary Bridger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2015 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| David Chilton Mitchell | VP Global Regulatory & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jan 2015 | 35,000 | 35,000 | - | - | Stock Option (Right to Buy) | |
| Stephen B. Shrewsbury | CMO; Senior VP Clinical Dev. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Dec 2014 | 400 | 400 | - | - | Common Stock | |
| Stephen B. Shrewsbury | CMO; Senior VP Clinical Dev. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2014 | 31,250 | 31,250 | - | - | Stock Option (Right to Buy) | |
| David J. Main | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2014 | 65,000 | 65,000 | - | - | Stock Option (Right to Buy) | |
| Kamran Alam | CFO, Vice President Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2014 | 31,250 | 31,250 | - | - | Stock Option (Right to Buy) | |
| Lloyd Mackenzie | VP Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2014 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| David J. Main | Director, President and CEO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 9,459 | 0 | - | - | Common Exchangeable Shares | |
| David J. Main | Director, President and CEO | 12 Mar 2014 | 71,530 | 0 | - | - | Common Exchangeable Shares | ||
| David J. Main | Director, President and CEO | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 9,459 | 71,530 | - | - | Common Special Voting Stock | |
| David J. Main | Director, President and CEO | 12 Mar 2014 | 71,530 | 0 | - | - | Common Special Voting Stock | ||
| David J. Main | Director, President and CEO | 12 Mar 2014 | 71,530 | 71,530 | - | - | Common Stock | ||
| Gary Bridger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2014 | 36,502 | 40,147 | - | - | Common Exchangeable Shares | |
| Gary Bridger | None | 12 Mar 2014 | 40,147 | 0 | - | - | Common Exchangeable Shares | ||
| Gary Bridger | None | 12 Mar 2014 | 284,090 | 0 | - | - | Series A-1 Exchangeable Shares | ||
| Gary Bridger | None | 12 Mar 2014 | 284,090 | 0 | - | - | Series A-1 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 284,090 | 0 | - | - | Series A-1 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 189,393 | 0 | - | - | Series A-2 Exchangeable Shares | ||
| Gary Bridger | None | 12 Mar 2014 | 189,393 | 0 | - | - | Series A-2 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 189,393 | 0 | - | - | Series A-2 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 326,538 | 0 | - | - | Series B-1 Exchangeable Shares | ||
| Gary Bridger | None | 12 Mar 2014 | 326,538 | 0 | - | - | Series B-1 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 326,538 | 0 | - | - | Series B-1 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 325,035 | 0 | - | - | Series B-2 Exchangeable Shares | ||
| Gary Bridger | None | 12 Mar 2014 | 325,035 | 0 | - | - | Series B-2 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 325,035 | 0 | - | - | Series B-2 Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 378,786 | 0 | - | - | Series C Exchangeable Shares | ||
| Gary Bridger | None | 12 Mar 2014 | 378,786 | 0 | - | - | Series C Preferred Stock | ||
| Gary Bridger | None | 12 Mar 2014 | 378,786 | 0 | - | - | Series C Preferred Stock | ||
| Gary Bridger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2014 | 36,502 | 40,147 | - | - | Common Special Voting Stock | |
| Gary Bridger | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 40,147 | 0 | - | - | Common Special Voting Stock | |
| Gary Bridger | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 284,090 | 0 | - | - | Series A-1 Special Voting Stock | |
| Gary Bridger | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 189,393 | 0 | - | - | Series A-2 Special Voting Stock | |
| Gary Bridger | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 326,538 | 0 | - | - | Series B-1 Special Voting Stock | |
| Gary Bridger | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 325,035 | 0 | - | - | Series B-2 Special Voting Stock | |
| Gary Bridger | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 12 Mar 2014 | 378,786 | 0 | - | - | Series C Special Voting Stock | |
| Gary Bridger | None | 12 Mar 2014 | 1,543,989 | 1,543,989 | - | - | Common Stock | ||
| Daniel J. Levitt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2014 | 8,333 | 20,051 | - | - | Stock Option (Right to Buy) | |
| Todd E. Simpson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2014 | 8,333 | 8,333 | - | - | Stock Option (Right to Buy) | |
| Robert E. Pelzer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2014 | 8,333 | 14,843 | - | - | Stock Option (Right to Buy) | |
| Gary Bridger | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2014 | 8,333 | 8,333 | - | - | Stock Option (Right to Buy) |