1.2M XNAS Volume
XNAS 04 Apr, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 2.20 per share. | 15 Jan 2025 | 17,378 | 319,859 | - | 2.2 | 38,232 | Common Stock |
| Alicia J. Hager | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 2.20 per share. | 15 Jan 2025 | 9,584 | 146,735 | - | 2.2 | 21,085 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 2.20 per share. | 15 Jan 2025 | 7,447 | 124,796 | - | 2.2 | 16,383 | Common Stock |
| David R. Shook | See Remarks | Sale of securities on an exchange or to another person at price $ 2.20 per share. | 15 Jan 2025 | 8,638 | 190,955 | - | 2.2 | 19,004 | Common Stock |
| Alyssa Levin | See Remarks | 15 Jan 2025 | 5,838 | 102,662 | - | 2.2 | 12,844 | Common Stock | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 565,500 | 565,500 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 94,500 | 337,237 | - | 0 | Common Stock | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 52,500 | 156,319 | - | 0 | Common Stock | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 105,000 | 105,000 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 62,000 | 93,376 | - | 0 | Common Stock | |
| Nadir Mahmood | President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 123,500 | 123,500 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 52,500 | 132,243 | - | 0 | Common Stock | |
| Ralph Brandenberger | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 105,000 | 105,000 | - | - | Stock Option (right to buy) | |
| David R. Shook | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 59,000 | 199,593 | - | 0 | Common Stock | |
| David R. Shook | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 117,500 | 117,500 | - | - | Stock Option (right to buy) | |
| Alyssa Levin | See Remarks | 03 Jan 2025 | 105,000 | 105,000 | - | - | Stock Option (right to buy) | ||
| Alyssa Levin | See Remarks | 03 Jan 2025 | 52,500 | 108,500 | - | 0 | Common Stock | ||
| David R. Shook | See Remarks | Grant, award, or other acquisition of securities at price $ 5.11 per share. | 21 Aug 2024 | 1,352 | 138,593 | - | 5.1 | 6,909 | Common Stock |
| Nadir Mahmood | President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2024 | 550,000 | 550,000 | - | - | Stock Option (right to buy) | |
| Alicia J. Hager | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 16 Jul 2024 | 3,396 | 103,819 | - | 8 | 27,168 | Common Stock |
| David R. Shook | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jul 2024 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| David R. Shook | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jul 2024 | 23,421 | 139,945 | - | 0 | Common Stock | |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 5.60 per share. | 18 Jun 2024 | 1,770 | 240,737 | - | 5.6 | 9,912 | Common Stock |
| Alicia J. Hager | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 5.60 per share. | 18 Jun 2024 | 727 | 107,215 | - | 5.6 | 4,071 | Common Stock |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 5.60 per share. | 18 Jun 2024 | 456 | 150,959 | - | 5.6 | 2,554 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 5.60 per share. | 18 Jun 2024 | 229 | 79,743 | - | 5.6 | 1,282 | Common Stock |
| David Shook | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.60 per share. | 18 Jun 2024 | 456 | 116,524 | - | 5.6 | 2,554 | Common Stock |
| Leone D Patterson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Simeon J. George | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Ali Behbahani | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Angela Thedinga | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Zachary Scheiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| George Vratsanos | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 45,000 | 45,000 | - | - | Stock Option (right to buy) | |
| Simeon George J. | Director | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 27 Mar 2024 | 451,659 | 451,659 | - | 10 | 4,516,590 | Common Stock |
| George Simeon J. | Director | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 27 Mar 2024 | 1,548,341 | 1,548,341 | - | 10 | 15,483,410 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 13.33 per share. | 01 Mar 2024 | 137,642 | 240,507 | - | 13.3 | 1,834,768 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 13.00 per share. | 01 Mar 2024 | 12,358 | 378,149 | - | 13 | 160,654 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 3,808 | 22,445 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 12.51 per share. | 01 Mar 2024 | 8,367 | 79,972 | - | 12.5 | 104,671 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 01 Mar 2024 | 2,955 | 88,339 | - | 3.9 | 11,495 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 01 Mar 2024 | 3,808 | 85,384 | - | 3.9 | 14,813 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 2,955 | 25,629 | - | - | Stock Option (right to buy) | |
| Trager James | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 12.00 per share. | 12 Feb 2024 | 4,143 | 149,415 | - | 12 | 49,716 | Common Stock |
| J. Hastings Paul | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 8.74 per share. | 16 Jan 2024 | 9,697 | 390,507 | - | 8.7 | 84,752 | Common Stock |
| Hager Alicia J. | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.74 per share. | 16 Jan 2024 | 4,554 | 107,942 | - | 8.7 | 39,802 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 8.74 per share. | 16 Jan 2024 | 2,512 | 81,576 | - | 8.7 | 21,955 | Common Stock |
| David Shook | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 8.74 per share. | 16 Jan 2024 | 3,552 | 114,980 | - | 8.7 | 31,044 | Common Stock |
| Trager James | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 8.74 per share. | 16 Jan 2024 | 4,560 | 153,558 | - | 8.7 | 39,854 | Common Stock |
| Hager Alicia J. | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 56,000 | 112,496 | - | 0 | Common Stock | |
| Hastings J. Paul | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 85,000 | 400,204 | - | 0 | Common Stock | |
| Levin Alyssa | See Remarks | 04 Jan 2024 | 56,000 | 56,000 | - | 0 | Common Stock | ||
| Shook David | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 112,500 | 112,500 | - | - | Stock Option (right to buy) | |
| Brandenberger Ralph | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 112,500 | 112,500 | - | - | Stock Option (right to buy) | |
| Trager James | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 56,000 | 158,118 | - | 0 | Common Stock | |
| J. Hager Alicia | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 112,500 | 112,500 | - | - | Stock Option (right to buy) | |
| David Shook | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 56,000 | 118,532 | - | 0 | Common Stock | |
| Levin Alyssa | See Remarks | 04 Jan 2024 | 112,500 | 112,500 | - | - | Stock Option (right to buy) | ||
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 112,500 | 112,500 | - | - | Stock Option (right to buy) | |
| Brandenberger Ralph | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 56,000 | 84,088 | - | 0 | Common Stock | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 509,500 | 509,500 | - | - | Stock Option (right to buy) | |
| David Shook | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.83 per share. | 21 Aug 2023 | 1,331 | 60,532 | - | 1.8 | 2,436 | Common Stock |
| David Shook | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2023 | 208,000 | 208,000 | - | - | Stock Option (right to buy) | |
| Alyssa Levin | See Remarks | 01 Jul 2023 | 442,400 | 442,400 | - | - | Stock Option (right to buy) | ||
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 4.85 per share. | 20 Jun 2023 | 1,704 | 313,402 | - | 4.8 | 8,264 | Common Stock |
| Alicia J. Hager | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 4.85 per share. | 20 Jun 2023 | 701 | 56,496 | - | 4.9 | 3,400 | Common Stock |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 4.85 per share. | 20 Jun 2023 | 526 | 85,776 | - | 4.8 | 2,551 | Common Stock |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 4.85 per share. | 20 Jun 2023 | 439 | 100,118 | - | 4.8 | 2,129 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 4.85 per share. | 20 Jun 2023 | 221 | 28,088 | - | 4.9 | 1,072 | Common Stock |
| David Shook | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 4.85 per share. | 20 Jun 2023 | 439 | 61,863 | - | 4.8 | 2,129 | Common Stock |
| Leone D Patterson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Simeon J. George | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Ali Behbahani | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Angela Thedinga | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Fouad Azzam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Zachary Scheiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2023 | 22,500 | 22,500 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 64,500 | 316,797 | - | 0 | Common Stock | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 386,500 | 386,500 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 13 Jan 2023 | 3,691 | 313,106 | - | 5.5 | 20,264 | Common Stock |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 37,500 | 58,300 | - | 0 | Common Stock | |
| Alicia J. Hager | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 13 Jan 2023 | 1,103 | 57,197 | - | 5.5 | 6,055 | Common Stock |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 37,500 | 85,424 | - | 0 | Common Stock | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 13 Jan 2023 | 1,122 | 84,302 | - | 5.5 | 6,160 | Common Stock |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 37,500 | 99,672 | - | 0 | Common Stock | |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 13 Jan 2023 | 1,115 | 98,557 | - | 5.5 | 6,121 | Common Stock |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 21,000 | 28,800 | - | 0 | Common Stock | |
| Ralph Brandenberger | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 42,000 | 42,000 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 13 Jan 2023 | 491 | 28,309 | - | 5.5 | 2,696 | Common Stock |
| David Shook | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 13 Jan 2023 | 175 | 60,302 | - | 5.5 | 961 | Common Stock |
| David Shook | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 37,500 | 60,477 | - | 0 | Common Stock | |
| David Shook | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jan 2023 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 13.01 per share. | 21 Sep 2022 | 6,126 | 274,335 | - | 13.0 | 79,717 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 15 Aug 2022 | 7,500 | 53,588 | - | 3.9 | 29,175 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 2,681 | 68,062 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 4,819 | 27,703 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 18.03 per share. | 15 Aug 2022 | 7,500 | 46,088 | - | 18.0 | 135,215 | Common Stock |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.53 per share. | 15 Aug 2022 | 5,000 | 62,172 | - | 17.5 | 87,656 | Common Stock |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 5,000 | 88,243 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 15 Aug 2022 | 5,000 | 67,172 | - | 3.9 | 19,450 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 15 Aug 2022 | 11,000 | 18,800 | - | 3.9 | 42,790 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 11,000 | 26,253 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 17.64 per share. | 15 Aug 2022 | 11,000 | 7,800 | - | 17.6 | 194,052 | Common Stock |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 15.32 per share. | 08 Aug 2022 | 7,500 | 46,088 | - | 15.3 | 114,900 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Aug 2022 | 7,500 | 32,522 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 08 Aug 2022 | 7,500 | 53,588 | - | 3.9 | 29,175 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 08 Aug 2022 | 6,886 | 19,053 | - | 3.9 | 26,787 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Aug 2022 | 340 | 8,445 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Aug 2022 | 6,886 | 37,253 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Aug 2022 | 4,367 | 0 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 15.51 per share. | 08 Aug 2022 | 11,593 | 7,800 | - | 15.5 | 179,783 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.77 per share. | 08 Aug 2022 | 340 | 19,393 | - | 4.8 | 1,622 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 08 Aug 2022 | 4,367 | 12,167 | - | 0.4 | 1,790 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 25 Jul 2022 | 7,500 | 53,588 | - | 3.9 | 29,175 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jul 2022 | 7,500 | 63,243 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 13.40 per share. | 25 Jul 2022 | 7,500 | 46,088 | - | 13.4 | 100,480 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 25 Jul 2022 | 3,000 | 10,800 | - | 0.4 | 1,230 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jul 2022 | 3,000 | 4,367 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 13.41 per share. | 25 Jul 2022 | 3,000 | 7,800 | - | 13.4 | 40,230 | Common Stock |
| Ralph Brandenberger | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jul 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 120,000 | 120,000 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 19,500 | 280,461 | - | 0 | Common Stock | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 8,000 | 20,800 | - | 0 | Common Stock | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 50,500 | 50,500 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 6,000 | 46,088 | - | 0 | Common Stock | |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 30,000 | 30,000 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 5,000 | 62,172 | - | 0 | Common Stock | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 2,500 | 7,800 | - | 0 | Common Stock | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Leone D. Patterson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Laura Shawver | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Simeon J. George | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Ali Behbahani | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Tiba Aynechi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Angela Thedinga | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 3,218 | 3,218 | - | - | Stock Option (right to buy) | |
| Fouad Azzam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Zachary Scheiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2022 | 16,000 | 16,000 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 2,037 | 44,139 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 1,358 | 29,426 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 405 | 8,785 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 340 | 7,367 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Sale of securities on an exchange or to another person at price $ 15.00 per share. | 03 Jun 2022 | 4,140 | 5,300 | - | 15 | 62,100 | Common Stock |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 03 Jun 2022 | 2,037 | 9,440 | - | 3.9 | 7,924 | Common Stock |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 03 Jun 2022 | 1,358 | 7,403 | - | 3.9 | 5,283 | Common Stock |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 03 Jun 2022 | 340 | 5,640 | - | 0.4 | 139 | Common Stock |
| Ralph Brandenberger | Sr. VP, Technical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.77 per share. | 03 Jun 2022 | 405 | 6,045 | - | 4.8 | 1,932 | Common Stock |
| Simeon J. George | Director | Purchase of securities on an exchange or from another person at price $ 15.00 per share. | 28 Apr 2022 | 666,666 | 666,666 | - | 15 | 9,999,990 | Common Stock |
| Simeon J. George | Director | Purchase of securities on an exchange or from another person at price $ 15.00 per share. | 28 Apr 2022 | 666,667 | 666,667 | - | 15 | 10,000,005 | Common Stock |
| Angela Thedinga | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Mar 2022 | 32,000 | 32,000 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 41,900 | 260,961 | - | 0 | Common Stock | |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 251,100 | 251,100 | - | - | Stock Option (right to buy) | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 76,800 | 76,800 | - | - | Stock Option (right to buy) | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 12,800 | 12,800 | - | 0 | Common Stock | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 12,800 | 40,088 | - | 0 | Common Stock | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 76,800 | 76,800 | - | - | Stock Option (right to buy) | |
| Kanya Rajangam | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 76,800 | 76,800 | - | - | Stock Option (right to buy) | |
| Kanya Rajangam | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 12,800 | 12,800 | - | 0 | Common Stock | |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 12,800 | 57,172 | - | 0 | Common Stock | |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 76,800 | 76,800 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 5,300 | 5,300 | - | 0 | Common Stock | |
| Ralph Brandenberger | Sr. VP, Technical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jan 2022 | 31,400 | 31,400 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 01 Sep 2021 | 340 | 340 | - | 0.4 | 139 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 2,037 | 48,213 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 1,358 | 32,142 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 405 | 9,595 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2021 | 340 | 8,047 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Sale of securities on an exchange or to another person at price $ 32.08 per share. | 01 Sep 2021 | 4,140 | 0 | - | 32.1 | 132,811 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 01 Sep 2021 | 2,037 | 4,140 | - | 3.9 | 7,924 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 01 Sep 2021 | 1,358 | 2,103 | - | 3.9 | 5,283 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.77 per share. | 01 Sep 2021 | 405 | 745 | - | 4.8 | 1,932 | Common Stock |
| Kanya Rajangam | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 37.28 per share. | 05 Aug 2021 | 10,000 | 0 | - | 37.3 | 372,800 | Common Stock |
| Kanya Rajangam | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Aug 2021 | 10,000 | 44,054 | - | - | Stock Option (right to buy) | |
| Kanya Rajangam | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 05 Aug 2021 | 10,000 | 10,000 | - | 0.4 | 4,100 | Common Stock |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 31.53 per share. | 02 Aug 2021 | 3,600 | 44,372 | - | 31.5 | 113,508 | Common Stock |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Aug 2021 | 2,250 | 55,412 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 02 Aug 2021 | 2,250 | 47,972 | - | 3.9 | 8,753 | Common Stock |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 31.71 per share. | 01 Jul 2021 | 6,500 | 27,288 | - | 31.7 | 206,115 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2021 | 3,500 | 70,743 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 01 Jul 2021 | 3,500 | 33,788 | - | 3.9 | 13,615 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 26.89 per share. | 21 Jun 2021 | 3,807 | 227,561 | - | 26.9 | 102,370 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 26.39 per share. | 21 Jun 2021 | 4,693 | 231,368 | - | 26.4 | 123,848 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 16 Jun 2021 | 1,800 | 30,288 | - | 3.9 | 7,002 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2021 | 1,800 | 47,522 | - | - | Stock Option (right to buy) | |
| Leone D. Patterson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2021 | 16,511 | 16,511 | - | - | Stock Option (right to buy) | |
| Laura Shawver | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2021 | 16,511 | 16,511 | - | - | Stock Option (right to buy) | |
| Simeon J. George | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2021 | 16,511 | 16,511 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2021 | 16,511 | 16,511 | - | - | Stock Option (right to buy) | |
| Fouad Azzam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2021 | 16,511 | 16,511 | - | - | Stock Option (right to buy) | |
| Zachary Scheiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2021 | 16,511 | 16,511 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 02 Jun 2021 | 340 | 340 | - | 0.4 | 139 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.77 per share. | 02 Jun 2021 | 405 | 745 | - | 4.8 | 1,932 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 02 Jun 2021 | 1,358 | 2,103 | - | 3.9 | 5,283 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 02 Jun 2021 | 2,037 | 4,140 | - | 3.9 | 7,924 | Common Stock |
| Ralph Brandenberger | See Remarks | Sale of securities on an exchange or to another person at price $ 24.50 per share. | 02 Jun 2021 | 4,140 | 0 | - | 24.5 | 101,430 | Common Stock |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jun 2021 | 340 | 8,387 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jun 2021 | 405 | 10,000 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jun 2021 | 1,358 | 33,500 | - | - | Stock Option (right to buy) | |
| Ralph Brandenberger | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jun 2021 | 2,037 | 50,250 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 27.16 per share. | 10 May 2021 | 3,000 | 28,488 | - | 27.2 | 81,480 | Common Stock |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 03 May 2021 | 2,250 | 47,972 | - | 3.9 | 8,753 | Common Stock |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 31.64 per share. | 03 May 2021 | 1,350 | 45,722 | - | 31.6 | 42,714 | Common Stock |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 May 2021 | 2,250 | 57,662 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 31.64 per share. | 03 May 2021 | 2,250 | 45,722 | - | 31.6 | 71,190 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2021 | 3,500 | 74,243 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 32.70 per share. | 01 Apr 2021 | 3,500 | 31,488 | - | 32.7 | 114,450 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 01 Apr 2021 | 3,500 | 34,988 | - | 3.9 | 13,615 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 31.24 per share. | 30 Mar 2021 | 2,409 | 239,191 | - | 31.2 | 75,257 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 32.21 per share. | 30 Mar 2021 | 3,130 | 236,061 | - | 32.2 | 100,817 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 30.23 per share. | 30 Mar 2021 | 11,461 | 241,600 | - | 30.2 | 346,466 | Common Stock |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 38.07 per share. | 01 Feb 2021 | 2,034 | 48,638 | - | 38.1 | 77,434 | Common Stock |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2021 | 2,800 | 79,600 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2021 | 2,250 | 59,912 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 01 Feb 2021 | 2,800 | 47,072 | - | 40 | 112,000 | Common Stock |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.00 per share. | 01 Feb 2021 | 2,800 | 49,872 | - | 18 | 50,400 | Common Stock |
| James Trager | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 39.46 per share. | 01 Feb 2021 | 1,566 | 47,072 | - | 39.5 | 61,794 | Common Stock |
| James Trager | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 01 Feb 2021 | 2,250 | 50,672 | - | 3.9 | 8,753 | Common Stock |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 48.86 per share. | 25 Jan 2021 | 2,000 | 34,988 | - | 48.9 | 97,720 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 25 Jan 2021 | 5,500 | 36,988 | - | 3.9 | 21,395 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jan 2021 | 5,500 | 77,743 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Sale of securities on an exchange or to another person at price $ 48.40 per share. | 25 Jan 2021 | 3,500 | 31,488 | - | 48.4 | 169,400 | Common Stock |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jan 2021 | 3,083 | 49,322 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.89 per share. | 14 Jan 2021 | 3,083 | 31,488 | - | 3.9 | 11,993 | Common Stock |
| Paul J. Hastings | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2021 | 157,500 | 157,500 | - | - | Stock Option (right to buy) | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2021 | 13,125 | 13,125 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2021 | 52,500 | 52,500 | - | - | Stock Option (right to buy) | |
| Kanya Rajangam | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2021 | 52,500 | 52,500 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jan 2021 | 52,500 | 52,500 | - | - | Stock Option (right to buy) | |
| Alicia J. Hager | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Oct 2020 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2020 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Leone Patterson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 18,300 | 18,300 | - | - | Stock Option (right to buy) | |
| Leone Patterson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 10,700 | 10,700 | - | - | Stock Option (right to buy) | |
| Paul J. Hastings | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 202,400 | 202,400 | - | - | Stock Option (right to buy) | |
| Laura Shawver | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 18,300 | 18,300 | - | - | Stock Option (right to buy) | |
| Laura Shawver | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 10,700 | 10,700 | - | - | Stock Option (right to buy) | |
| Matthew J. Plunkett | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 77,800 | 77,800 | - | - | Stock Option (right to buy) | |
| Simeon J. George | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 10,700 | 10,700 | - | - | Stock Option (right to buy) | |
| Michael Dybbs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 10,700 | 10,700 | - | - | Stock Option (right to buy) | |
| Ali Behbahani | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 10,700 | 10,700 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 48,400 | 48,400 | - | - | Stock Option (right to buy) | |
| Nadir Mahmood | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 27,600 | 27,600 | - | - | Stock Option (right to buy) | |
| Kanya Rajangam | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 70,600 | 70,600 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 82,400 | 82,400 | - | - | Stock Option (right to buy) | |
| James Trager | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 31,100 | 31,100 | - | - | Stock Option (right to buy) | |
| Fouad Azzam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 10,700 | 10,700 | - | - | Stock Option (right to buy) | |
| Zachary Scheiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2020 | 10,700 | 10,700 | - | - | Stock Option (right to buy) |