Insider Trading disclosures for Macrogenics Inc

The latest disclosure was made by Ezio Bonvini in Macrogenics Inc where a trade of 16,665 Restricted Stock Unit done was reported to US exchanges on Feb. 15, 2025.

Insider trading is the trading of a company’s securities by individuals with access to confidential or material non-public information about the company. A company is required to report trading by corporate officers, directors, or other company members with significant access to privileged information to the Securities and Exchange Commission (SEC).

Client Name	Client Category	Action	Reported to Exchange	Quantity	Post Transaction Holding	Traded %	Avg. Price	Value	Security Type
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	16,665	16,665	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	16,665	124,414 (0%)	0%		0	Common Stock
Scott Koenig	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	42,329	777,415 (1%)	0%		0	Common Stock
Scott Koenig	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	42,329	42,330	-		-	Restricted Stock Unit
James Karrels	SVP, CFO and Secretary	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.56 per share.	15 Feb 2025	5,790	186,801 (0%)	0%	2.6	14,822	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	14,998	14,999	-		-	Restricted Stock Unit
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	14,998	192,591 (0%)	0%		0	Common Stock
Eric Risser	Chief Operating Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.56 per share.	15 Feb 2025	6,433	55,989 (0%)	0%	2.6	16,468	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	16,665	16,665	-		-	Restricted Stock Unit
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	16,665	62,422 (0%)	0%		0	Common Stock
Stephen L. Eck	Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	16,665	16,665	-		-	Restricted Stock Unit
Stephen L. Eck	Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.56 per share.	15 Feb 2025	4,942	29,377 (0%)	0%	2.6	12,652	Common Stock
Stephen L. Eck	Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	16,665	34,319 (0%)	0%		0	Common Stock
Thomas Spitznagel	Sr VP, Technical Ops	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.56 per share.	15 Feb 2025	5,520	21,402 (0%)	0%	2.6	14,131	Common Stock
Thomas Spitznagel	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	13,332	13,332	-		-	Restricted Stock Unit
Thomas Spitznagel	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	13,332	26,922 (0%)	0%		0	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	13,332	13,332	-		-	Restricted Stock Unit
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	13,332	18,858 (0%)	0%		0	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.56 per share.	15 Feb 2025	5,147	13,711 (0%)	0%	2.6	13,176	Common Stock
Beth Smith	VP, Controller & Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	1,095	1,095	-		-	Restricted Stock Unit
Beth Smith	VP, Controller & Treasurer	Sale of securities on an exchange or to another person at price $ 2.56 per share.	15 Feb 2025	423	9,532 (0%)	0%	2.6	1,083	Common Stock
Beth Smith	VP, Controller & Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2025	1,095	9,955 (0%)	0%		0	Common Stock
Scott Koenig	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2025	31,673	735,086 (1%)	0%		0	Common Stock
Scott Koenig	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Feb 2025	31,673	63,327	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	21,000	21,000	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.60 per share.	07 Feb 2025	4,311	107,749 (0%)	0%	2.6	11,209	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	11,168	112,060 (0%)	0%		-	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	128,000	128,000	-		-	Employee Stock Option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	11,168	22,332	-		-	Restricted Stock Unit
James Karrels	SVP, CFO and Secretary	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.60 per share.	07 Feb 2025	3,861	177,593 (0%)	0%	2.6	10,039	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	10,002	19,998	-		-	Restricted Stock Unit
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	19,000	19,000	-		-	Restricted Stock Unit
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	113,000	113,000	-		-	Employee Stock Option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	10,002	181,454 (0%)	0%		-	Common Stock
Eric Risser	Chief Operating Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.60 per share.	07 Feb 2025	4,311	45,757 (0%)	0%	2.6	11,209	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	11,168	22,332	-		-	Restricted Stock Unit
Eric Risser	Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	20,000	20,000	-		-	Restricted Stock Unit
Eric Risser	Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	120,000	120,000	-		-	Employee Stock Option (right to buy)
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	11,168	50,068 (0%)	0%		-	Common Stock
Stephen L. Eck	Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	11,168	22,332	-		-	Restricted Stock Unit
Stephen L. Eck	Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	11,168	20,966 (0%)	0%		0	Common Stock
Stephen L. Eck	Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.60 per share.	07 Feb 2025	3,312	17,654 (0%)	0%	2.6	8,611	Common Stock
Stephen L. Eck	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	113,000	113,000	-		-	Employee Stock Option (right to buy)
Stephen L. Eck	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	19,000	19,000	-		-	Restricted Stock Unit
Thomas Spitznagel	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	9,001	17,999	-		-	Restricted Stock Unit
Thomas Spitznagel	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	9,001	17,317 (0%)	0%		-	Common Stock
Thomas Spitznagel	Sr VP, Technical Ops	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.60 per share.	07 Feb 2025	3,727	13,590 (0%)	0%	2.6	9,690	Common Stock
Thomas Spitznagel	Sr VP, Technical Ops	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	105,000	105,000	-		-	Employee Stock Option (right to buy)
Thomas Spitznagel	Sr VP, Technical Ops	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	18,000	18,000	-		-	Restricted Stock Unit
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	9,001	9,001 (0%)	0%		-	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	9,001	17,999	-		-	Restricted Stock Unit
Jeffrey Stuart Peters	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	18,000	18,000	-		-	Restricted Stock Unit
Jeffrey Stuart Peters	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	105,000	105,000	-		-	Employee Stock Option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.60 per share.	07 Feb 2025	3,475	5,526 (0%)	0%	2.6	9,035	Common Stock
Beth Smith	VP, Controller & Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	1,583	9,472 (0%)	0%		-	Common Stock
Beth Smith	VP, Controller & Treasurer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.60 per share.	07 Feb 2025	612	8,860 (0%)	0%	2.6	1,591	Common Stock
Beth Smith	VP, Controller & Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	47,050	47,050	-		-	Employee Stock Option (right to buy)
Beth Smith	VP, Controller & Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	07 Feb 2025	7,850	7,850	-		-	Restricted Stock Unit
Beth Smith	VP, Controller & Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Feb 2025	1,583	3,167	-		-	Restricted Stock Unit
Scott Koenig	Director, President and CEO		07 Oct 2024	53,265	427,480 (0%)	0%		-	Common Stock
Scott Koenig	Director, President and CEO		07 Oct 2024	53,265	0 (0%)	0%		-	Common Stock
Scott Koenig	Director, President and CEO		23 Sep 2024	374,215	703,413 (1%)	0%		-	Common Stock
Scott Koenig	Director, President and CEO		23 Sep 2024	374,215	374,215 (0%)	0%		-	Common Stock
David C. Stump	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
David C. Stump	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
William K. Heiden	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
William K. Heiden	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
Edward M. Hurwitz	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
Edward M. Hurwitz	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
Margaret A. Liu	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
Margaret A. Liu	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Employee Stock Option (right to buy)
Margaret A. Liu	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
Scott T. Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
Scott T. Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
Karen Jean Ferrante	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
Karen Jean Ferrante	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
Jay Siegel	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
Jay Siegel	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
Federica O'Brien	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Stock Option (right to buy)
Federica O'Brien	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	6,500	6,500	-		-	Restricted Stock Unit
Margaret A. Liu	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2024	16,500	16,500	-		-	Employee Stock Option (right to buy)
David C. Stump	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
David C. Stump	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	4,500 (0%)	0%		0	Common Stock
William K. Heiden	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	4,500 (0%)	0%		0	Common Stock
William K. Heiden	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
Edward M. Hurwitz	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	37,574 (0%)	0%		0	Common Stock
Edward M. Hurwitz	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
Margaret A. Liu	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
Margaret A. Liu	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	4,500 (0%)	0%		0	Common Stock
Scott T. Jackson	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	4,500 (0%)	0%		0	Common Stock
Scott T. Jackson	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
Karen Jean Ferrante	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	4,500 (0%)	0%		0	Common Stock
Karen Jean Ferrante	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
Jay Siegel	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	4,500 (0%)	0%		0	Common Stock
Jay Siegel	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
Federica O'Brien	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	0	-		-	Restricted Stock Unit
Federica O'Brien	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2024	4,500	4,500 (0%)	0%		0	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.82 per share.	04 Apr 2024	42,500	51,395 (0%)	0%	4.8	204,850	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Apr 2024	42,500	127,500	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 18.22 per share.	04 Apr 2024	3,165	0 (0%)	0%	18.2	57,666	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 17.74 per share.	04 Apr 2024	5,351	3,165 (0%)	0%	17.7	94,927	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 16.38 per share.	04 Apr 2024	232	8,516 (0%)	0%	16.4	3,800	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 15.51 per share.	04 Apr 2024	147	8,748 (0%)	0%	15.5	2,280	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 15.07 per share.	04 Apr 2024	42,500	8,895 (0%)	0%	15.1	640,475	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Mar 2024	8,750	39,375	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Mar 2024	10,875	0	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 21.50 per share.	06 Mar 2024	19,625	8,895 (0%)	0%	21.5	421,938	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.15 per share.	06 Mar 2024	8,750	28,520 (0%)	0%	10.2	88,813	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.50 per share.	06 Mar 2024	10,875	19,770 (0%)	0%	11.5	125,063	Common Stock
James Karrels	SVP, CFO and Secretary	Sale of securities on an exchange or to another person at price $ 20.50 per share.	04 Mar 2024	30,000	171,452 (0%)	0%	20.5	615,000	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Mar 2024	15,000	155,000	-		-	Employee stock option (right to buy)
Eric Risser	Chief Operating Officer	Sale of securities on an exchange or to another person at price $ 19.63 per share.	04 Mar 2024	26,159	38,900 (0%)	0%	19.6	513,501	Common Stock
Eric Risser	Chief Operating Officer	Sale of securities on an exchange or to another person at price $ 20.00 per share.	04 Mar 2024	15,000	65,059 (0%)	0%	20	300,000	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.15 per share.	04 Mar 2024	15,000	80,059 (0%)	0%	10.2	152,250	Common Stock
Thomas Spitznagel	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Mar 2024	10,000	77,000	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, Technical Ops	Sale of securities on an exchange or to another person at price $ 20.00 per share.	04 Mar 2024	10,000	8,316 (0%)	0%	20	200,000	Common Stock
Thomas Spitznagel	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.50 per share.	04 Mar 2024	10,000	18,316 (0%)	0%	11.5	115,000	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 17.22 per share.	26 Feb 2024	16,124	8,895 (0%)	0%	17.2	277,655	Common Stock
Jeffrey Peters Stuart	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2024	26,250	0	-		-	Restricted Stock Unit
Peters Jeffrey Stuart	Senior VP and General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.11 per share.	22 Feb 2024	10,126	25,019 (0%)	0%	17.1	173,256	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.11 per share.	22 Feb 2024	9,366	100,892 (0%)	0%	17.1	160,252	Common Stock
Jeffrey Peters Stuart	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2024	26,250	35,145 (0%)	0%		0	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2024	28,125	0	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2024	28,125	110,258 (0%)	0%		0	Common Stock
Cilinski Lynn	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	6,668	8,591 (0%)	0%		0	Common Stock
Eck Stephen L.	Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.40 per share.	15 Feb 2024	6,872	9,798 (0%)	0%	17.4	119,573	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	16,670	70,938 (0%)	0%		0	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.40 per share.	15 Feb 2024	5,871	82,133 (0%)	0%	17.4	102,155	Common Stock
Koenig Scott	Director, President and CEO		15 Feb 2024	42,341	1,091,977 (2%)	0%		0	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	16,670	88,004 (0%)	0%		0	Common Stock
Scott Koenig	Director, President and CEO		15 Feb 2024	14,349	1,077,628 (2%)	0%	17.4	249,673	Common Stock
Cilinski Lynn	VP, Controller and Treasurer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.40 per share.	15 Feb 2024	2,378	6,213 (0%)	0%	17.4	41,377	Common Stock
Peters Stuart Jeffrey	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	13,336	13,336 (0%)	0%		0	Common Stock
Spitznagel Thomas	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	13,336	13,336 (0%)	0%		0	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	13,336	26,664	-		-	Restricted Stock Unit
Eck L. Stephen	Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	16,670	16,670 (0%)	0%		0	Common Stock
Peters Stuart Jeffrey	Senior VP and General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.40 per share.	15 Feb 2024	4,441	8,895 (0%)	0%	17.4	77,273	Common Stock
Thomas Spitznagel	Sr VP, Technical Ops	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.40 per share.	15 Feb 2024	5,020	8,316 (0%)	0%	17.4	87,348	Common Stock
Cilinski Lynn	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	6,668	13,332	-		-	Restricted Stock Unit
L. Stephen Eck	Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	16,670	33,330	-		-	Restricted Stock Unit
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	15,003	206,779 (0%)	0%		0	Common Stock
Koenig Scott	Director, President and CEO		15 Feb 2024	42,341	84,659	-		-	Restricted Stock Unit
Spitznagel Thomas	Sr VP, Technical Ops	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	13,336	26,664	-		-	Restricted Stock Unit
Karrels James	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	15,003	29,997	-		-	Restricted Stock Unit
Risser Eric	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	16,670	33,330	-		-	Restricted Stock Unit
Karrels James	SVP, CFO and Secretary	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.40 per share.	15 Feb 2024	5,327	201,452 (0%)	0%	17.4	92,690	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Feb 2024	16,670	33,330	-		-	Restricted Stock Unit
Risser Eric	Chief Operating Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.40 per share.	15 Feb 2024	5,879	65,059 (0%)	0%	17.4	102,295	Common Stock
Spitznagel Thomas	Sr VP, Technical Ops	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	71,000	71,000	-		-	Employee Stock Option (right to buy)
Karrels James	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	30,000	30,000	-		-	Restricted Stock Unit
Eric Risser	Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	90,000	90,000	-		-	Employee Stock Option (right to buy)
Scott Koenig	Director, President and CEO		08 Feb 2024	248,000	248,000	-		-	Employee Stock Option (right to buy)
L. Stephen Eck	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	90,000	90,000	-		-	Employee Stock Option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	33,500	33,500	-		-	Restricted Stock Unit
L. Eck Stephen	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	33,500	33,500	-		-	Restricted Stock Unit
Scott Koenig	Director, President and CEO		08 Feb 2024	95,000	95,000	-		-	Restricted Stock Unit
Cilinski Lynn	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	45,000	45,000	-		-	Employee Stock Option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	27,000	27,000	-		-	Restricted Stock Unit
Bonvini Ezio	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	90,000	90,000	-		-	Employee Stock Option (right to buy)
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	80,000	80,000	-		-	Employee Stock Option (right to buy)
Cilinski Lynn	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	17,000	17,000	-		-	Restricted Stock Unit
Risser Eric	Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	33,500	33,500	-		-	Restricted Stock Unit
Spitznagel Thomas	Sr VP, Technical Ops	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	27,000	27,000	-		-	Restricted Stock Unit
Peters Stuart Jeffrey	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	08 Feb 2024	71,000	71,000	-		-	Employee Stock Option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Sale of securities on an exchange or to another person at price $ 18.00 per share.	07 Feb 2024	3,334	71,334 (0%)	0%	18	60,012	Common Stock
Stuart Jeffrey Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Feb 2024	21,875	48,125	-		-	Employee stock option (right to buy)
Peters Jeffrey Stuart	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.50 per share.	05 Feb 2024	54,376	54,376 (0%)	0%	11.5	625,324	Common Stock
Peters Jeffrey Stuart	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 16.50 per share.	05 Feb 2024	54,376	21,875 (0%)	0%	16.5	897,204	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Feb 2024	54,376	10,875	-		-	Employee stock option (right to buy)
Stuart Peters Jeffrey	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 16.50 per share.	05 Feb 2024	21,875	0 (0%)	0%	16.5	360,938	Common Stock
Peters Stuart Jeffrey	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.15 per share.	05 Feb 2024	21,875	76,251 (0%)	0%	10.1	222,031	Common Stock
Bonvini Ezio	Sr VP, Research & CSO	Sale of securities on an exchange or to another person at price $ 15.00 per share.	01 Feb 2024	13,316	74,668 (0%)	0%	15	199,740	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Sale of securities on an exchange or to another person at price $ 12.00 per share.	19 Jan 2024	13,316	87,984 (0%)	0%	12	159,792	Common Stock
Bonvini Ezio	Sr VP, Research & CSO	Sale of securities on an exchange or to another person at price $ 10.08 per share.	20 Dec 2023	18,880	101,300 (0%)	0%	10.1	190,310	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Sale of securities on an exchange or to another person at price $ 6.03 per share.	10 Mar 2023	5,372	0 (0%)	0%	6.0	32,393	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2023	9,375	0	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2023	9,375	123,799 (0%)	0%		0	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.55 per share.	22 Feb 2023	3,619	120,180 (0%)	0%	6.5	23,704	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2023	8,750	0	-		-	Restricted Stock Unit
Jeffrey Stuart Peters	Senior VP and General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.55 per share.	22 Feb 2023	3,378	5,372 (0%)	0%	6.6	22,126	Common Stock
Jeffrey Stuart Peters	Senior VP and General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2023	8,750	8,750 (0%)	0%		0	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	50,000	50,000	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	200,000	200,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	75,000	75,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	20,000	20,000	-		-	Restricted Stock Unit
Scott Koenig	Director, President and CEO		15 Feb 2023	510,000	510,000	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		15 Feb 2023	127,000	127,000	-		-	Restricted Stock Unit
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	180,000	180,000	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	45,000	45,000	-		-	Restricted Stock Unit
Eric Risser	Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	200,000	200,000	-		-	Employee stock option (right to buy)
Eric Risser	Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	50,000	50,000	-		-	Restricted Stock Unit
Stephen L. Eck	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	200,000	200,000	-		-	Employee stock option (right to buy)
Stephen L. Eck	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	50,000	50,000	-		-	Restricted Stock Unit
Thomas Spitznagel	Sr VP, Technical Ops	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	40,000	40,000	-		-	Restricted Stock Unit
Thomas Spitznagel	Sr VP, Technical Ops	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	170,000	170,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	40,000	40,000	-		-	Restricted Stock Unit
Jeffrey Stuart Peters	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Feb 2023	170,000	170,000	-		-	Employee stock option (right to buy)
Margaret A. Liu	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Jan 2023	36,000	36,000	-		-	Stock Option (right to buy)
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	28 Oct 2022	8,500	53,468 (0%)	0%	1.5	12,835	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Oct 2022	8,500	0	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Purchase of securities on an exchange or from another person at price $ 2.47 per share.	15 Jun 2022	40,000	191,776 (0%)	0%	2.5	98,800	Common Stock
William K. Heiden	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	36,000	36,000	-		-	Stock Option (right to buy)
David C. Stump	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	18,000	18,000	-		-	Stock Option (right to buy)
Edward M. Hurwitz	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	18,000	18,000	-		-	Stock Option (right to buy)
Scott T. Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	18,000	18,000	-		-	Stock Option (right to buy)
Karen Jean Ferrante	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	18,000	18,000	-		-	Stock Option (right to buy)
Karen Jean Ferrante	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	20,640	20,640	-		-	Stock Option (right to buy)
Jay Siegel	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	24,080	24,080	-		-	Stock Option (right to buy)
Jay Siegel	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	18,000	18,000	-		-	Stock Option (right to buy)
Federica O'Brien	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	18,000	18,000	-		-	Stock Option (right to buy)
Federica O'Brien	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 May 2022	24,080	24,080	-		-	Stock Option (right to buy)
Scott Koenig	Director, President and CEO		16 May 2022	53,265	0	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		16 May 2022	53,265	1,049,636 (2%)	0%	1.5	80,430	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 May 2022	5,000	0	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 May 2022	5,000	116,090 (0%)	0%		0	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.16 per share.	14 May 2022	1,666	114,424 (0%)	0%	4.2	6,931	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Mar 2022	8,316	0	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	28 Mar 2022	8,316	151,776 (0%)	0%	1.5	12,557	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	04 Mar 2022	500	44,968 (0%)	0%	0.9	470	Common Stock
Eric Risser	Chief Operating Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Mar 2022	500	0	-		-	Employee stock option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	37,500	37,500	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	75,000	75,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	63,400	63,400	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		22 Feb 2022	480,000	480,000	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	140,000	140,000	-		-	Employee stock option (right to buy)
Eric Risser	Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	170,000	170,000	-		-	Employee stock option (right to buy)
Stephen L. Eck	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	150,000	150,000	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, Technical Ops	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	140,000	140,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	70,000	70,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	Senior VP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	35,000	35,000	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share.	16 Nov 2021	2,540	111,090 (0%)	0%	16	40,640	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Nov 2021	2,540	0	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.51 per share.	16 Jul 2021	5,000	5,000 (0%)	0%	7.5	37,550	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Jul 2021	5,000	37,147	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Sale of securities on an exchange or to another person at price $ 25.01 per share.	16 Jul 2021	5,000	0 (0%)	0%	25.0	125,050	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 20.53 per share.	24 Jun 2021	4,221	108,550 (0%)	0%	20.5	86,657	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jun 2021	4,221	63,279	-		-	Employee stock option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jun 2021	21,855	2,540	-		-	Employee stock option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share.	24 Jun 2021	21,855	104,329 (0%)	0%	16	349,680	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 May 2021	5,000	5,000	-		-	Restricted Stock Unit
Ezio Bonvini	Sr VP, Research & CSO	Payment of exercise price or tax liability using portion of securities received from the company at price $ 29.49 per share.	14 May 2021	2,416	82,474 (0%)	0%	29.5	71,248	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 May 2021	5,000	84,890 (0%)	0%		-	Common Stock
David C. Stump	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Edward M. Hurwitz	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Scott T. Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Paulo F. Costa	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Kenneth Galbraith	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Karen Jean Ferrante	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Jay Siegel	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Federica O'Brien	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 May 2021	15,000	15,000	-		-	Stock Option (right to buy)
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Apr 2021	5,000	42,147	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.51 per share.	15 Apr 2021	5,000	5,000 (0%)	0%	7.5	37,550	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Sale of securities on an exchange or to another person at price $ 30.91 per share.	15 Apr 2021	5,000	0 (0%)	0%	30.9	154,550	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Sale of securities on an exchange or to another person at price $ 32.00 per share.	22 Mar 2021	3,917	79,890 (0%)	0%	32	125,344	Common Stock
James Karrels	SVP, CFO and Secretary	Sale of securities on an exchange or to another person at price $ 33.00 per share.	22 Mar 2021	15,000	143,460 (0%)	0%	33	495,000	Common Stock
Jeffrey Stuart Peters	General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.50 per share.	08 Mar 2021	21,749	21,749 (0%)	0%	11.5	250,114	Common Stock
Jeffrey Stuart Peters	General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Mar 2021	21,749	65,251	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	General Counsel	Sale of securities on an exchange or to another person at price $ 26.50 per share.	08 Mar 2021	21,749	0 (0%)	0%	26.5	576,349	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2021	120,000	120,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2021	40,000	40,000	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		22 Feb 2021	280,000	280,000	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2021	95,000	95,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2021	95,000	95,000	-		-	Employee stock option (right to buy)
Stephen L. Eck	Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2021	60,000	60,000	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2021	95,000	95,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2021	90,000	90,000	-		-	Employee stock option (right to buy)
Federica O'Brien	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	10 Feb 2021	30,000	30,000	-		-	Stock Option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	28 Jan 2021	5,000	158,460 (0%)	0%	1.5	7,550	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Jan 2021	5,000	8,316	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Jan 2021	1,000	0	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	28 Jan 2021	1,000	153,460 (0%)	0%	0.9	940	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	29 Dec 2020	500	8,500	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 24.10 per share.	29 Dec 2020	500	44,468 (0%)	0%	24.1	12,050	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	29 Dec 2020	500	44,968 (0%)	0%	1.5	755	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	30 Nov 2020	500	44,968 (0%)	0%	1.5	755	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Nov 2020	500	9,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 23.35 per share.	30 Nov 2020	500	44,468 (0%)	0%	23.4	11,675	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 20.69 per share.	28 Oct 2020	1,500	44,468 (0%)	0%	20.7	31,035	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Oct 2020	1,500	9,500	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	28 Oct 2020	1,500	45,968 (0%)	0%	1.5	2,265	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 25.33 per share.	28 Sep 2020	500	44,468 (0%)	0%	25.3	12,665	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Sep 2020	500	11,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	28 Sep 2020	500	44,968 (0%)	0%	1.5	755	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Sale of securities on an exchange or to another person at price $ 32.00 per share.	17 Sep 2020	18,339	83,807 (0%)	0%	32	586,848	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Sale of securities on an exchange or to another person at price $ 29.88 per share.	17 Sep 2020	44,512	102,146 (0%)	0%	29.9	1,330,019	Common Stock
Kenneth Galbraith	Director	Sale of securities on an exchange or to another person at price $ 27.11 per share.	09 Sep 2020	13,849	0 (0%)	0%	27.1	375,446	Common Stock
Kenneth Galbraith	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Sep 2020	6,924	0	-		-	Stock Option (right to buy)
Kenneth Galbraith	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Sep 2020	13,849	0	-		-	Stock Option (right to buy)
Kenneth Galbraith	Director	Sale of securities on an exchange or to another person at price $ 27.11 per share.	09 Sep 2020	6,924	0 (0%)	0%	27.1	187,710	Common Stock
Kenneth Galbraith	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 20.15 per share.	09 Sep 2020	6,924	6,924 (0%)	0%	20.2	139,519	Common Stock
Kenneth Galbraith	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share.	09 Sep 2020	13,849	13,849 (0%)	0%	16	221,584	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Aug 2020	500	11,500	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 27.10 per share.	26 Aug 2020	500	44,468 (0%)	0%	27.1	13,550	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	26 Aug 2020	500	44,968 (0%)	0%	1.5	755	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 Aug 2020	7,500	47,147	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Sale of securities on an exchange or to another person at price $ 26.87 per share.	20 Aug 2020	7,500	0 (0%)	0%	26.9	201,525	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.51 per share.	20 Aug 2020	7,500	7,500 (0%)	0%	7.5	56,325	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 25.63 per share.	27 Jul 2020	3,000	44,468 (0%)	0%	25.6	76,890	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 25.14 per share.	27 Jul 2020	1,000	47,468 (0%)	0%	25.1	25,140	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	27 Jul 2020	4,000	48,468 (0%)	0%	1.5	6,040	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	27 Jul 2020	489	44,957 (0%)	0%	0.9	460	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 25.13 per share.	27 Jul 2020	489	44,468 (0%)	0%	25.1	12,289	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Jul 2020	4,000	12,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Jul 2020	489	0	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 30.00 per share.	02 Jul 2020	3,100	44,468 (0%)	0%	30	93,000	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	02 Jul 2020	3,100	47,568 (0%)	0%	1.5	4,681	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Jul 2020	3,100	16,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	General Counsel	Sale of securities on an exchange or to another person at price $ 30.00 per share.	02 Jul 2020	202	0 (0%)	0%	30	6,060	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 28.49 per share.	24 Jun 2020	500	44,468 (0%)	0%	28.5	14,245	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jun 2020	500	489	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	24 Jun 2020	500	44,968 (0%)	0%	0.9	470	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 May 2020	500	989	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	26 May 2020	500	44,968 (0%)	0%	0.9	470	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 26.59 per share.	26 May 2020	500	44,468 (0%)	0%	26.6	13,295	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.51 per share.	20 May 2020	7,500	7,500 (0%)	0%	7.5	56,325	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Sale of securities on an exchange or to another person at price $ 25.30 per share.	20 May 2020	7,500	0 (0%)	0%	25.3	189,750	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2020	7,500	54,647	-		-	Employee stock option (right to buy)
David C. Stump	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	15,000	15,000	-		-	Stock Option (right to buy)
Edward M. Hurwitz	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	15,000	15,000	-		-	Stock Option (right to buy)
Scott T. Jackson	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	15,000	15,000	-		-	Stock Option (right to buy)
Paulo F. Costa	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	15,000	15,000	-		-	Stock Option (right to buy)
Kenneth Galbraith	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	15,000	15,000	-		-	Stock Option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	10,000	10,000	-		-	Restricted Stock Unit
Karen Jean Ferrante	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	15,000	15,000	-		-	Stock Option (right to buy)
Jay Siegel	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 May 2020	15,000	15,000	-		-	Stock Option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	06 May 2020	7,532	52,500 (0%)	0%	1.5	11,373	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 May 2020	7,532	19,100	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 May 2020	500	1,489	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 25.00 per share.	06 May 2020	3,532	44,468 (0%)	0%	25	88,300	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 20.00 per share.	06 May 2020	3,000	48,000 (0%)	0%	20	60,000	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 15.00 per share.	06 May 2020	1,000	51,000 (0%)	0%	15	15,000	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 10.00 per share.	06 May 2020	500	52,000 (0%)	0%	10	5,000	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	06 May 2020	500	44,968 (0%)	0%	0.9	470	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Apr 2020	6,000	1,989	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	16 Apr 2020	6,000	44,468 (0%)	0%	0.9	5,640	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	13 Mar 2020	6,000	500	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	13 Mar 2020	6,000	38,468 (0%)	0%	0.9	5,640	Common Stock
Scott Koenig	Director, President and CEO		11 Mar 2020	133,163	943,103 (1%)	0%	0.9	125,173	Common Stock
Scott Koenig	Director, President and CEO		11 Mar 2020	133,163	0	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Mar 2020	4,473	1,000	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	06 Mar 2020	4,473	152,460 (0%)	0%	0.9	4,205	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Feb 2020	100,000	100,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Feb 2020	35,000	35,000	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		20 Feb 2020	290,000	290,000	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Feb 2020	90,000	90,000	-		-	Employee stock option (right to buy)
Jon Marc Wigginton	Sr VP, Clinical Dev. & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Feb 2020	100,000	100,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 10.84 per share.	20 Feb 2020	500	32,468 (0%)	0%	10.8	5,420	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Feb 2020	90,000	90,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 Feb 2020	500	6,500	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	20 Feb 2020	500	32,968 (0%)	0%	0.9	470	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Feb 2020	87,000	87,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Feb 2020	87,000	87,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 10.00 per share.	04 Feb 2020	30	32,468 (0%)	0%	10	300	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Feb 2020	623	7,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Feb 2020	30	7,623	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 10.00 per share.	04 Feb 2020	623	32,468 (0%)	0%	10	6,230	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	04 Feb 2020	623	33,091 (0%)	0%	0.9	586	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share.	04 Feb 2020	30	32,498 (0%)	0%	0.9	28	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	30 Jan 2020	7,320	142,807 (0%)	0%	0.9	6,881	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2020	5,180	5,473	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	30 Jan 2020	5,180	147,987 (0%)	0%	0.9	4,869	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2020	7,320	0	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	27 Sep 2019	1,662	32,468 (0%)	0%	0.9	1,562	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Sep 2019	1,662	0	-		-	Stock Option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2019	3,000	7,653	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 19.03 per share.	20 May 2019	1,000	30,806 (0%)	0%	19.0	19,026	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	20 May 2019	1,000	31,806 (0%)	0%	0.9	940	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 18.38 per share.	20 May 2019	3,000	30,806 (0%)	0%	18.4	55,131	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	20 May 2019	3,000	33,806 (0%)	0%	0.9	2,820	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 May 2019	1,000	1,662	-		-	Stock Option (right to buy)
David C. Stump	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Matthew K. Fust	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Edward M. Hurwitz	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Scott T. Jackson	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Paulo F. Costa	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	7,357	7,357	-		-	Stock Option (right to buy)
Paulo F. Costa	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Kenneth Galbraith	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Karen Jean Ferrante	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Karen Jean Ferrante	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	4,616	4,616	-		-	Stock Option (right to buy)
Jay Siegel	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 May 2019	10,000	10,000	-		-	Stock Option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Mar 2019	2,497	0	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	14 Mar 2019	2,497	30,806 (0%)	0%	0.9	2,347	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Feb 2019	90,000	90,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Feb 2019	35,000	35,000	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		21 Feb 2019	260,000	260,000	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Feb 2019	85,000	85,000	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Feb 2019	90,000	90,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Feb 2019	85,000	85,000	-		-	Employee stock option (right to buy)
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Feb 2019	70,000	70,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Feb 2019	70,000	70,000	-		-	Employee stock option (right to buy)
Matthew K. Fust	None	Exercise or conversion of derivative security received from the company (such as an option) at price $ 20.15 per share.	06 Feb 2019	6,924	7,424 (0%)	0%	20.2	139,519	Common Stock
Matthew K. Fust	None	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Feb 2019	6,924	0	-		-	Stock Option (right to buy)
Matthew K. Fust	None	Sale of securities on an exchange or to another person at price $ 29.38 per share.	06 Feb 2019	6,924	500 (0%)	0%	29.4	203,427	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Sale of securities on an exchange or to another person at price $ 30.00 per share.	06 Feb 2019	1,770	0 (0%)	0%	30	53,100	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.51 per share.	06 Feb 2019	1,770	1,770 (0%)	0%	7.5	13,293	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Feb 2019	1,770	62,147	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	General Counsel	Sale of securities on an exchange or to another person at price $ 30.00 per share.	06 Feb 2019	68	202 (0%)	0%	30	2,040	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Jan 2019	6,000	2,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	28 Jan 2019	6,000	28,309 (0%)	0%	0.9	5,640	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jan 2019	5,326	0	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	24 Jan 2019	2,000	135,487 (0%)	0%	0.9	1,880	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	24 Jan 2019	5,326	133,487 (0%)	0%	0.9	5,006	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jan 2019	2,000	7,320	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Jan 2019	5,314	0	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	08 Jan 2019	5,314	128,161 (0%)	0%	0.9	4,995	Common Stock
Scott Koenig	Director, President and CEO		03 Jan 2019	39,897	0	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		03 Jan 2019	39,897	213,060 (0%)	0%	0.9	37,503	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	18 Dec 2018	5,000	5,314	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	18 Dec 2018	5,000	122,847 (0%)	0%	0.9	4,700	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	12 Dec 2018	5,000	4,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	12 Dec 2018	5,000	22,309 (0%)	0%	0.9	4,700	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Nov 2018	3,000	1,420	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	27 Nov 2018	3,000	117,847 (0%)	0%	0.9	2,820	Common Stock
Scott Koenig	Director, President and CEO		13 Nov 2018	40,000	39,897	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		13 Nov 2018	40,000	173,163 (0%)	0%	0.9	37,600	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	13 Nov 2018	4,000	9,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	13 Nov 2018	4,000	16,100 (0%)	0%	0.9	3,760	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Oct 2018	3,000	13,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	22 Oct 2018	3,000	12,100 (0%)	0%	0.9	2,820	Common Stock
David C. Stump	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Matthew K. Fust	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Edward M. Hurwitz	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Scott T. Jackson	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Paulo F. Costa	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Paulo F. Costa	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	6,293	6,293	-		-	Stock Option (right to buy)
Kenneth Galbraith	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Karen Jean Ferrante	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Jay Siegel	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 May 2018	10,000	10,000	-		-	Stock Option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	12 Mar 2018	1,000	20,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 31.08 per share.	12 Mar 2018	1,000	9,100 (0%)	0%	31.1	31,080	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	12 Mar 2018	1,000	10,100 (0%)	0%	0.9	940	Common Stock
James Karrels	SVP, CFO and Secretary	Sale of securities on an exchange or to another person at price $ 31.00 per share.	05 Mar 2018	5,000	114,847 (0%)	0%	31	155,000	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2018	70,000	70,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2018	28,000	28,000	-		-	Employee stock option (right to buy)
Scott Koenig	Director, President and CEO		02 Mar 2018	225,000	225,000	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2018	70,000	70,000	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2018	70,000	70,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 30.00 per share.	02 Mar 2018	4,000	9,100 (0%)	0%	30	120,000	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2018	70,000	70,000	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Mar 2018	4,000	21,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	02 Mar 2018	4,000	13,100 (0%)	0%	0.9	3,760	Common Stock
Thomas Spitznagel	Sr VP, BPD & Manufacturing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2018	50,000	50,000	-		-	Employee stock option (right to buy)
Jeffrey Stuart Peters	Acting General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2018	50,000	50,000	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Feb 2018	7,989	0	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	28 Feb 2018	7,989	9,912 (0%)	0%	0.9	7,510	Common Stock
Lynn Cilinski	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	28 Feb 2018	7,989	17,901 (0%)	0%	0.9	7,510	Common Stock
Lynn Cilinski	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	28 Feb 2018	7,989	25,890 (0%)	0%	1.5	12,063	Common Stock
Lynn Cilinski	VP, Controller and Treasurer	Sale of securities on an exchange or to another person at price $ 25.01 per share.	28 Feb 2018	23,967	1,923 (0%)	0%	25.0	599,436	Common Stock
Lynn Cilinski	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Feb 2018	7,989	0	-		-	Employee stock option (right to buy)
Lynn Cilinski	VP, Controller and Treasurer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Feb 2018	7,989	0	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Feb 2018	1,000	25,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	28 Feb 2018	1,000	10,100 (0%)	0%	0.9	940	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 25.00 per share.	28 Feb 2018	1,000	9,100 (0%)	0%	25.0	25,005	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.46 per share.	26 Feb 2018	11,070	18,930 (0%)	0%	23.5	259,702	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Sale of securities on an exchange or to another person at price $ 22.50 per share.	24 Jan 2018	3,000	9,100 (0%)	0%	22.5	67,500	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Jan 2018	3,000	26,497	-		-	Employee stock option (right to buy)
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	24 Jan 2018	3,000	12,100 (0%)	0%	0.9	2,820	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	17 Jan 2018	2,000	9,100 (0%)	0%	0.9	1,880	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	17 Jan 2018	2,000	29,497	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Jan 2018	6,516	0	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	16 Jan 2018	6,516	119,847 (0%)	0%	0.9	6,125	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Sale of securities on an exchange or to another person at price $ 20.00 per share.	16 Jan 2018	2,524	30,000 (0%)	0%	20	50,480	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Jan 2018	2,476	47,972	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Jan 2018	2,524	45,448	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.70 per share.	16 Jan 2018	2,476	32,476 (0%)	0%	4.7	11,637	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Sale of securities on an exchange or to another person at price $ 20.00 per share.	16 Jan 2018	2,476	30,000 (0%)	0%	20	49,520	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.70 per share.	16 Jan 2018	2,524	32,524 (0%)	0%	4.7	11,863	Common Stock
Jeffrey Stuart Peters	Acting General Counsel	Grant, award, or other acquisition of securities at price $ 15.05 per share.	31 Dec 2017	270	270 (0%)	0%	15.1	4,064	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	29 Dec 2017	3,000	6,516	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	29 Dec 2017	3,000	113,331 (0%)	0%	0.9	2,820	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	21 Nov 2017	5,000	50,448	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Sale of securities on an exchange or to another person at price $ 20.00 per share.	21 Nov 2017	5,000	30,000 (0%)	0%	20	100,000	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.70 per share.	21 Nov 2017	5,000	35,000 (0%)	0%	4.7	23,500	Common Stock
Jay Siegel	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	13 Nov 2017	20,000	20,000	-		-	Stock Option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Oct 2017	10,000	55,448	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Sale of securities on an exchange or to another person at price $ 20.00 per share.	25 Oct 2017	10,000	30,000 (0%)	0%	20	200,000	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.70 per share.	25 Oct 2017	10,000	40,000 (0%)	0%	4.7	47,000	Common Stock
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Sep 2017	5,000	9,516	-		-	Employee stock option (right to buy)
James Karrels	SVP, CFO and Secretary	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	05 Sep 2017	5,000	110,331 (0%)	0%	0.9	4,700	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	05 Sep 2017	2,000	6,000 (0%)	0%	0.9	1,880	Common Stock
Eric Risser	Sr VP & Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Sep 2017	2,000	31,497	-		-	Employee stock option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Jul 2017	26,632	0	-		-	Employee stock option (right to buy)
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share.	26 Jul 2017	26,632	146,658 (0%)	0%	0.9	25,034	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.51 per share.	26 Jul 2017	26,632	120,026 (0%)	0%	1.5	40,214	Common Stock
Ezio Bonvini	Sr VP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Jul 2017	26,632	0	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jun 2017	5,000	65,448	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.70 per share.	05 Jun 2017	5,000	35,000 (0%)	0%	4.7	23,500	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Sale of securities on an exchange or to another person at price $ 20.00 per share.	05 Jun 2017	5,000	30,000 (0%)	0%	20	100,000	Common Stock
David C. Stump	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	10,000	10,000	-		-	Stock Option (right to buy)
Matthew K. Fust	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	10,000	10,000	-		-	Stock Option (right to buy)
Edward M. Hurwitz	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	10,000	10,000	-		-	Stock Option (right to buy)
Scott T. Jackson	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	10,000	10,000	-		-	Stock Option (right to buy)
Paulo F. Costa	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	10,000	10,000	-		-	Stock Option (right to buy)
Paulo F. Costa	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	6,057	6,057	-		-	Stock Option (right to buy)
Kenneth Galbraith	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	10,000	10,000	-		-	Stock Option (right to buy)
Karen Jean Ferrante	None	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 May 2017	10,000	10,000	-		-	Stock Option (right to buy)
Atul Saran	SVP & General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.61 per share.	28 Apr 2017	1,862	16,986 (0%)	0%	21.6	40,238	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	19 Apr 2017	15,000	70,448	-		-	Employee stock option (right to buy)
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.70 per share.	19 Apr 2017	15,000	45,000 (0%)	0%	4.7	70,500	Common Stock
Jon Wigginton	Sr VP, Clinical Dev. & CMO	Sale of securities on an exchange or to another person at price $ 20.00 per share.	19 Apr 2017	15,000	30,000 (0%)	0%	20	300,000	Common Stock

*All Values are in $ Million

Client Category: Promoter/ KMP/ Director / Immediate Relatives / Employee / etc
Security Type: Share/ Warrants / Convertible Debentures

Data as reported to USA Exchanges

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Insider Trading disclosures for Macrogenics Inc

The latest disclosure was made by Ezio Bonvini in Macrogenics Inc where a trade of 16,665 Restricted Stock Unit done was reported to US exchanges on Feb. 15, 2025.

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