552.8K XNYS Volume
XNYS 18 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 187.08 per share. | 03 Mar 2025 | 478 | 7,259 (0%) | 0% | 187.1 | 89,424 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 186.20 per share. | 03 Mar 2025 | 1,233 | 7,737 (0%) | 0% | 186.2 | 229,587 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 185.37 per share. | 03 Mar 2025 | 2,236 | 8,970 (0%) | 0% | 185.4 | 414,485 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 185.60 per share. | 03 Mar 2025 | 2,287 | 15,500 (0%) | 0% | 185.6 | 424,467 | Common Stock |
| Bryan K. Phillips | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 186.45 per share. | 24 Feb 2025 | 2,206 | 13,236 (0%) | 0% | 186.5 | 411,309 | Common Stock |
| Bryan K. Phillips | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Feb 2025 | 6,152 | 15,442 (0%) | 0% | 0 | Common Stock | |
| Randall A. Ban | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Feb 2025 | 6,152 | 13,411 (0%) | 0% | 0 | Common Stock | |
| Randall A. Ban | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 186.45 per share. | 24 Feb 2025 | 2,205 | 11,206 (0%) | 0% | 186.4 | 411,122 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 186.45 per share. | 24 Feb 2025 | 8,273 | 35,149 (0%) | 0% | 186.5 | 1,542,501 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Feb 2025 | 18,458 | 43,422 (0%) | 0% | 0 | Common Stock | |
| John C. Rondoni | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 186.45 per share. | 24 Feb 2025 | 1,009 | 17,787 (0%) | 0% | 186.4 | 188,128 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Feb 2025 | 3,296 | 18,796 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 21 Feb 2025 | 125 | 1,475 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 21 Feb 2025 | 125 | 1,475 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 21 Feb 2025 | 500 | 32,174 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 186.45 per share. | 21 Feb 2025 | 2,200 | 36,126 (0%) | 0% | 186.5 | 410,190 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2025 | 6,152 | 38,326 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 21 Feb 2025 | 125 | 1,475 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 21 Feb 2025 | 125 | 1,475 (0%) | 0% | 0 | Common Stock | |
| John C. Rondoni | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 5,076 | 15,500 (0%) | 0% | 0 | Common Stock | |
| Melissa Mann | Chief People Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 5,076 | 8,266 (0%) | 0% | 0 | Common Stock | |
| Jason P. Kelly | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 4,541 | 4,541 (0%) | 0% | 0 | Common Stock | |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 170.49 per share. | 09 Feb 2025 | 583 | 10,424 (0%) | 0% | 170.5 | 99,396 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 182.15 per share. | 09 Feb 2025 | 315 | 11,007 (0%) | 0% | 182.1 | 57,377 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 185.84 per share. | 09 Feb 2025 | 3,824 | 11,184 (0%) | 0% | 185.8 | 710,646 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 186.96 per share. | 09 Feb 2025 | 3,341 | 7,843 (0%) | 0% | 187.0 | 624,648 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 187.66 per share. | 09 Feb 2025 | 584 | 7,259 (0%) | 0% | 187.7 | 109,593 | Common Stock |
| Randall A. Ban | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Feb 2025 | 25,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Randall A. Ban | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 182.15 per share. | 09 Feb 2025 | 314 | 2,767 (0%) | 0% | 182.1 | 57,195 | Common Stock |
| Randall A. Ban | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2025 | 5,076 | 7,843 (0%) | 0% | 0 | Common Stock | |
| Randall A. Ban | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 67.63 per share. | 09 Feb 2025 | 25,000 | 32,843 (0%) | 0% | 67.6 | 1,690,750 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 178.54 per share. | 09 Feb 2025 | 2,500 | 30,343 (0%) | 0% | 178.5 | 446,340 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 179.41 per share. | 09 Feb 2025 | 1,000 | 29,343 (0%) | 0% | 179.4 | 179,407 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 180.79 per share. | 09 Feb 2025 | 1,330 | 28,013 (0%) | 0% | 180.8 | 240,447 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 181.90 per share. | 09 Feb 2025 | 3,770 | 24,243 (0%) | 0% | 181.9 | 685,757 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 182.90 per share. | 09 Feb 2025 | 3,242 | 21,001 (0%) | 0% | 182.9 | 592,947 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 183.79 per share. | 09 Feb 2025 | 2,541 | 18,460 (0%) | 0% | 183.8 | 467,016 | Common Stock |
| Randall A. Ban | See Remarks | Sale of securities on an exchange or to another person at price $ 184.81 per share. | 09 Feb 2025 | 3,452 | 15,008 (0%) | 0% | 184.8 | 637,965 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2025 | 5,076 | 32,674 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 182.15 per share. | 09 Feb 2025 | 314 | 27,598 (0%) | 0% | 182.1 | 57,195 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 182.15 per share. | 09 Feb 2025 | 896 | 8,935 (0%) | 0% | 182.1 | 163,206 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2025 | 16,029 | 24,964 (0%) | 0% | 0 | Common Stock | |
| Carlton W. Weatherby | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2025 | 5,076 | 7,457 (0%) | 0% | 0 | Common Stock | |
| Carlton W. Weatherby | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 182.15 per share. | 09 Feb 2025 | 313 | 2,381 (0%) | 0% | 182.2 | 57,013 | Common Stock |
| Bryan K. Phillips | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 182.15 per share. | 29 Jan 2025 | 282 | 4,214 (0%) | 0% | 182.1 | 51,366 | Common Stock |
| Bryan K. Phillips | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 189.99 per share. | 29 Jan 2025 | 204 | 4,496 (0%) | 0% | 190.0 | 38,758 | Common Stock |
| Bryan K. Phillips | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2025 | 5,076 | 9,290 (0%) | 0% | 0 | Common Stock | |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 176.33 per share. | 15 Jan 2025 | 137 | 4,426 (0%) | 0% | 176.3 | 24,157 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 176.33 per share. | 15 Jan 2025 | 92 | 2,592 (0%) | 0% | 176.3 | 16,222 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 176.33 per share. | 15 Jan 2025 | 81 | 20,512 (0%) | 0% | 176.3 | 14,283 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 176.32 per share. | 15 Jan 2025 | 80 | 2,293 (0%) | 0% | 176.3 | 14,106 | Common Stock |
| Herbert P. Timothy | Director, CEO and President | Other type of transaction at price $ 0.00 per share. | 20 Dec 2024 | 28,840 | 54,934 | - | - | Stock Option (Right to Buy) | |
| P. Herbert Timothy | Director, CEO and President | Other type of transaction at price $ 0.00 per share. | 20 Dec 2024 | 2,915 | 5,553 | - | - | Stock Option (Right to Buy) | |
| P. Herbert Timothy | Director, CEO and President | Other type of transaction at price $ 0.00 per share. | 20 Dec 2024 | 61,770 | 117,658 (0%) | 0% | - | Common Stock | |
| P. Herbert Timothy | Director, CEO and President | Other type of transaction at price $ 0.00 per share. | 20 Dec 2024 | 27,254 | 51,913 | - | - | Stock Option (Right to Buy) | |
| Herbert P. Timothy | Director, CEO and President | Other type of transaction at price $ 0.00 per share. | 20 Dec 2024 | 13,703 | 26,100 | - | - | Stock Option (Right to Buy) | |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 71.00 per share. | 01 Nov 2024 | 5,802 | 17,150 (0%) | 0% | 71 | 411,942 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2024 | 2,901 | 9,197 | - | - | Employee Stock Option (Right to Buy) | |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2024 | 5,802 | 1,448 | - | - | Employee Stock Option (Right to Buy) | |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 196.42 per share. | 01 Nov 2024 | 333 | 11,348 (0%) | 0% | 196.4 | 65,408 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 194.84 per share. | 01 Nov 2024 | 1,013 | 11,681 (0%) | 0% | 194.8 | 197,373 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 193.92 per share. | 01 Nov 2024 | 1,580 | 12,694 (0%) | 0% | 193.9 | 306,394 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 192.93 per share. | 01 Nov 2024 | 5,777 | 14,274 (0%) | 0% | 192.9 | 1,114,557 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 01 Nov 2024 | 2,901 | 20,051 (0%) | 0% | 42.1 | 122,277 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 210.46 per share. | 14 Oct 2024 | 115 | 4,289 (0%) | 0% | 210.5 | 24,203 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 210.45 per share. | 14 Oct 2024 | 77 | 2,500 (0%) | 0% | 210.5 | 16,205 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 210.46 per share. | 14 Oct 2024 | 68 | 20,431 (0%) | 0% | 210.5 | 14,311 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 210.46 per share. | 14 Oct 2024 | 79 | 2,213 (0%) | 0% | 210.5 | 16,626 | Common Stock |
| Shawn T. McCormick | Director | Sale of securities on an exchange or to another person at price $ 220.00 per share. | 09 Sep 2024 | 800 | 23,140 (0%) | 0% | 220 | 176,000 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 215.00 per share. | 09 Sep 2024 | 31 | 11,348 (0%) | 0% | 215 | 6,665 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 189.16 per share. | 22 Aug 2024 | 1,201 | 15,178 (0%) | 0% | 189.2 | 227,181 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 71.00 per share. | 22 Aug 2024 | 5,000 | 16,379 (0%) | 0% | 71 | 355,000 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Aug 2024 | 5,000 | 7,250 | - | - | Employee Stock Option (Right to Buy) | |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 190.04 per share. | 22 Aug 2024 | 3,799 | 11,379 (0%) | 0% | 190.0 | 721,962 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 15 Aug 2024 | 16,139 | 19,195 (0%) | 0% | 42.2 | 680,259 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2024 | 16,139 | 4,861 | - | - | Stock Option (Right to Buy) | |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2024 | 4,861 | 0 | - | - | Stock Option (Right to Buy) | |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 189.64 per share. | 15 Aug 2024 | 895 | 3,056 (0%) | 0% | 189.6 | 169,728 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 188.66 per share. | 15 Aug 2024 | 3,066 | 3,951 (0%) | 0% | 188.7 | 578,432 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 187.10 per share. | 15 Aug 2024 | 900 | 7,017 (0%) | 0% | 187.1 | 168,390 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 15 Aug 2024 | 4,861 | 7,917 (0%) | 0% | 42.1 | 204,891 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 194.91 per share. | 15 Aug 2024 | 2,350 | 3,056 (0%) | 0% | 194.9 | 458,039 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 193.92 per share. | 15 Aug 2024 | 8,132 | 5,406 (0%) | 0% | 193.9 | 1,576,957 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 192.60 per share. | 15 Aug 2024 | 1,150 | 13,538 (0%) | 0% | 192.6 | 221,490 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 191.92 per share. | 15 Aug 2024 | 2,072 | 14,688 (0%) | 0% | 191.9 | 397,658 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 190.20 per share. | 15 Aug 2024 | 1,659 | 16,760 (0%) | 0% | 190.2 | 315,542 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 189.06 per share. | 15 Aug 2024 | 776 | 18,419 (0%) | 0% | 189.1 | 146,711 | Common Stock |
| Shawn T. McCormick | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Aug 2024 | 7,518 | 0 | - | - | Stock Option (Right to Buy) | |
| Shawn T. McCormick | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Aug 2024 | 1,019 | 0 | - | - | Stock Option (Right to Buy) | |
| Shawn T. McCormick | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 14 Aug 2024 | 8,537 | 23,940 (0%) | 0% | 0.9 | 8,025 | Common Stock |
| Melissa Mann | Chief People Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2024 | 3,190 | 3,190 (0%) | 0% | 0 | Common Stock | |
| Melissa Mann | Chief People Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2024 | 5,248 | 5,248 | - | - | Employee Stock Option (Right to Buy) | |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 138.58 per share. | 15 Jul 2024 | 154 | 4,174 (0%) | 0% | 138.6 | 21,341 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 138.58 per share. | 15 Jul 2024 | 117 | 2,423 (0%) | 0% | 138.6 | 16,214 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 138.58 per share. | 15 Jul 2024 | 103 | 20,363 (0%) | 0% | 138.6 | 14,274 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 138.59 per share. | 15 Jul 2024 | 32 | 2,134 (0%) | 0% | 138.6 | 4,435 | Common Stock |
| Timothy P. Herbert | Director, CEO, President & Chairperson | Gift of securities by or to the insider at price $ 0.00 per share. | 31 May 2024 | 3,000 | 112,731 (0%) | 0% | 0 | Common Stock | |
| Charisse Y. Sparks | Chief Medical Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 29 May 2024 | 64 | 3,628 (0%) | 0% | 0 | Common Stock | |
| Shawn T. McCormick | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2024 | 2,500 | 1,019 | - | - | Stock Option (Right to Buy) | |
| Shawn T. McCormick | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 10 May 2024 | 2,500 | 15,403 (0%) | 0% | 0.9 | 2,350 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 4,020 (0%) | 0% | 0 | Common Stock | |
| Dana G. Mead | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 21,385 (0%) | 0% | 0 | Common Stock | |
| Shawn T. McCormick | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 12,903 (0%) | 0% | 0 | Common Stock | |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 2,306 (0%) | 0% | 0 | Common Stock | |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 20,260 (0%) | 0% | 0 | Common Stock | |
| Myriam J. Curet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 2,100 (0%) | 0% | 0 | Common Stock | |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 2,102 (0%) | 0% | 0 | Common Stock | |
| Cynthia B. Burks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2024 | 716 | 1,385 (0%) | 0% | 0 | Common Stock | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 240.68 per share. | 29 Apr 2024 | 1,175 | 35,620 (0%) | 0% | 240.7 | 282,799 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Apr 2024 | 1,175 | 0 | - | - | Stock Option (Right to Buy) | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Apr 2024 | 125 | 1,350 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Apr 2024 | 125 | 1,350 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Apr 2024 | 500 | 27,771 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Apr 2024 | 125 | 1,350 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Apr 2024 | 125 | 1,350 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 230.03 per share. | 17 Apr 2024 | 15,000 | 28,271 (0%) | 0% | 230.0 | 3,450,450 | Common Stock |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 231.74 per share. | 12 Apr 2024 | 107 | 34,445 (0%) | 0% | 231.7 | 24,796 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 231.74 per share. | 12 Apr 2024 | 70 | 3,304 (0%) | 0% | 231.7 | 16,222 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 231.74 per share. | 12 Apr 2024 | 70 | 1,590 (0%) | 0% | 231.7 | 16,222 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 231.74 per share. | 12 Apr 2024 | 62 | 19,544 (0%) | 0% | 231.7 | 14,368 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 231.73 per share. | 12 Apr 2024 | 56 | 1,386 (0%) | 0% | 231.7 | 12,977 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 01 Apr 2024 | 296 | 10,932 (0%) | 0% | 16 | 4,736 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 214.00 per share. | 01 Apr 2024 | 32 | 10,900 (0%) | 0% | 214 | 6,848 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2024 | 296 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 207.25 per share. | 01 Apr 2024 | 1,420 | 67,132 (0%) | 0% | 207.3 | 294,295 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 206.19 per share. | 01 Apr 2024 | 3,379 | 68,552 (0%) | 0% | 206.2 | 696,716 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 205.27 per share. | 01 Apr 2024 | 11,645 | 71,931 (0%) | 0% | 205.3 | 2,390,369 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 204.35 per share. | 01 Apr 2024 | 10,694 | 83,576 (0%) | 0% | 204.4 | 2,185,319 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 203.33 per share. | 01 Apr 2024 | 9,388 | 94,270 (0%) | 0% | 203.3 | 1,908,862 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 213.26 per share. | 01 Apr 2024 | 440 | 63,658 (0%) | 0% | 213.3 | 93,834 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 210.99 per share. | 01 Apr 2024 | 232 | 64,098 (0%) | 0% | 211.0 | 48,950 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 209.46 per share. | 01 Apr 2024 | 1,310 | 64,330 (0%) | 0% | 209.5 | 274,393 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 208.34 per share. | 01 Apr 2024 | 1,492 | 65,640 (0%) | 0% | 208.3 | 310,843 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 207.25 per share. | 01 Apr 2024 | 1,420 | 67,132 (0%) | 0% | 207.3 | 294,295 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 206.19 per share. | 01 Apr 2024 | 3,379 | 68,552 (0%) | 0% | 206.2 | 696,716 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 205.27 per share. | 01 Apr 2024 | 11,645 | 71,931 (0%) | 0% | 205.3 | 2,390,369 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 204.35 per share. | 01 Apr 2024 | 10,694 | 83,576 (0%) | 0% | 204.4 | 2,185,319 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 203.33 per share. | 01 Apr 2024 | 9,388 | 94,270 (0%) | 0% | 203.3 | 1,908,862 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 213.26 per share. | 01 Apr 2024 | 440 | 63,658 (0%) | 0% | 213.3 | 93,834 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 210.99 per share. | 01 Apr 2024 | 232 | 64,098 (0%) | 0% | 211.0 | 48,950 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 209.46 per share. | 01 Apr 2024 | 1,310 | 64,330 (0%) | 0% | 209.5 | 274,393 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 208.34 per share. | 01 Apr 2024 | 1,492 | 65,640 (0%) | 0% | 208.3 | 310,843 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 01 Apr 2024 | 3,273 | 34,338 (0%) | 0% | 16 | 52,368 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2024 | 3,273 | 5,313 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Mar 2024 | 2,000 | 8,586 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 27 Mar 2024 | 2,000 | 31,065 (0%) | 0% | 16 | 32,000 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 211.29 per share. | 27 Mar 2024 | 1,243 | 29,065 (0%) | 0% | 211.3 | 262,633 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Mar 2024 | 1,243 | 0 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Mar 2024 | 1,000 | 296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 25 Mar 2024 | 1,000 | 11,190 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 197.81 per share. | 25 Mar 2024 | 54 | 11,136 (0%) | 0% | 197.8 | 10,682 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 197.81 per share. | 25 Mar 2024 | 500 | 10,636 (0%) | 0% | 197.8 | 98,905 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 194.46 per share. | 22 Mar 2024 | 3,062 | 11,770 (0%) | 0% | 194.5 | 595,437 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 193.70 per share. | 22 Mar 2024 | 825 | 14,832 (0%) | 0% | 193.7 | 159,803 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 195.22 per share. | 22 Mar 2024 | 500 | 11,270 (0%) | 0% | 195.2 | 97,610 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 18 Mar 2024 | 1,000 | 10,744 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Mar 2024 | 1,000 | 1,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 193.53 per share. | 18 Mar 2024 | 500 | 10,190 (0%) | 0% | 193.5 | 96,765 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 193.54 per share. | 18 Mar 2024 | 54 | 10,690 (0%) | 0% | 193.5 | 10,451 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 11 Mar 2024 | 1,000 | 10,298 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2024 | 1,000 | 2,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 198.05 per share. | 11 Mar 2024 | 500 | 9,744 (0%) | 0% | 198.1 | 99,025 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 198.06 per share. | 11 Mar 2024 | 54 | 10,244 (0%) | 0% | 198.1 | 10,695 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 1,000 | 3,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 179.44 per share. | 01 Mar 2024 | 500 | 8,298 (0%) | 0% | 179.4 | 89,720 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 179.44 per share. | 01 Mar 2024 | 54 | 9,798 (0%) | 0% | 179.4 | 9,690 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 2,555 | 0 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 01 Mar 2024 | 2,555 | 27,822 (0%) | 0% | 0.9 | 2,402 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 01 Mar 2024 | 1,000 | 9,852 (0%) | 0% | 16 | 16,000 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 179.26 per share. | 29 Feb 2024 | 2,255 | 15,657 (0%) | 0% | 179.3 | 404,231 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 179.98 per share. | 29 Feb 2024 | 80 | 17,964 (0%) | 0% | 180.0 | 14,398 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 179.23 per share. | 29 Feb 2024 | 6,218 | 18,044 (0%) | 0% | 179.2 | 1,114,452 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 179.98 per share. | 29 Feb 2024 | 52 | 17,912 (0%) | 0% | 180.0 | 9,359 | Common Stock |
| A. Randall Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 23 Feb 2024 | 3,060 | 6,089 (0%) | 0% | 42.2 | 128,979 | Common Stock |
| Ban A. Randall | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 3,060 | 21,000 | - | - | Stock Option (Right to Buy) | |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 23 Feb 2024 | 940 | 15,259 (0%) | 0% | 42.2 | 39,621 | Common Stock |
| Ban A. Randall | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 11,090 | 0 | - | - | Stock Option (Right to Buy) | |
| Ban Randall A. | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 185.37 per share. | 23 Feb 2024 | 12,230 | 3,029 (0%) | 0% | 185.4 | 2,267,075 | Common Stock |
| A. Randall Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 940 | 24,060 | - | - | Stock Option (Right to Buy) | |
| Ban Randall A. | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 200 | 0 | - | - | Stock Option (Right to Buy) | |
| Randall Ban A. | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 23 Feb 2024 | 11,290 | 14,319 (0%) | 0% | 0.9 | 10,613 | Common Stock |
| Ban A. Randall | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 182.01 per share. | 23 Feb 2024 | 3,060 | 3,029 (0%) | 0% | 182.0 | 556,951 | Common Stock |
| Rondoni John C. | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.07 per share. | 15 Feb 2024 | 8,000 | 24,262 (0%) | 0% | 2.1 | 16,560 | Common Stock |
| John Rondoni C. | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 8,000 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| A. Randall Ban | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 2,694 | 3,029 (0%) | 0% | 0 | Common Stock | |
| Herbert Timothy P. | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 13,755 | 13,755 | - | - | Employee Stock Option (Right to Buy) | |
| Weatherby Carlton | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 4,376 | 4,376 | - | - | Employee Stock Option (Right to Buy) | |
| Nelson Marilyn Carlson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 09 Feb 2024 | 4,000 | 25,267 (0%) | 0% | 0.9 | 3,760 | Common Stock |
| Y. Charisse Sparks | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 2,694 | 3,692 (0%) | 0% | 0 | Common Stock | |
| Bryan Phillips K. | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 4,376 | 4,376 | - | - | Employee Stock Option (Right to Buy) | |
| Ebeling Philip J. | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 2,694 | 3,027 (0%) | 0% | 0 | Common Stock | |
| Y. Sparks Charisse | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 4,376 | 4,376 | - | - | Employee Stock Option (Right to Buy) | |
| Nelson Marilyn Carlson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Feb 2024 | 4,000 | 2,555 | - | - | Stock Option (Right to Buy) | |
| Randall Ban A. | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 4,376 | 4,376 | - | - | Employee Stock Option (Right to Buy) | |
| J. Richard Buchholz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 2,694 | 43,271 (0%) | 0% | 0 | Common Stock | |
| Philip Ebeling J. | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 4,376 | 4,376 | - | - | Employee Stock Option (Right to Buy) | |
| J. Buchholz Richard | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 4,376 | 4,376 | - | - | Employee Stock Option (Right to Buy) | |
| John Rondoni C. | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 2,694 | 16,262 (0%) | 0% | 0 | Common Stock | |
| Timothy Herbert P. | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 8,467 | 9,690 (0%) | 0% | 0 | Common Stock | |
| Carlton Weatherby | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 2,694 | 2,694 (0%) | 0% | 0 | Common Stock | |
| Phillips K. Bryan | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 2,694 | 4,571 (0%) | 0% | 0 | Common Stock | |
| C. John Rondoni | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 4,376 | 4,376 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2024 | 16,225 | 3,100 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 30 Jan 2024 | 16,225 | 23,096 (0%) | 0% | 0.9 | 15,252 | Common Stock |
| Bryan K. Phillips | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 216.61 per share. | 29 Jan 2024 | 205 | 1,877 (0%) | 0% | 216.6 | 44,405 | Common Stock |
| Tansey M. Casey | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jan 2024 | 500 | 500 (0%) | 0% | 0 | Common Stock | |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 326.00 per share. | 16 Jan 2024 | 2 | 1,242 (0%) | 0% | 326 | 652 | Common Stock |
| M. Casey Tansey | Director | Grant, award, or other acquisition of securities at price $ 150.50 per share. | 16 Jan 2024 | 8 | 19,405 (0%) | 0% | 150.5 | 1,204 | Common Stock |
| L. Ellis Gary | Director | Grant, award, or other acquisition of securities at price $ 186.10 per share. | 16 Jan 2024 | 87 | 3,234 (0%) | 0% | 186.1 | 16,191 | Common Stock |
| Garinois-Melenikiotou Georgia | Director | Grant, award, or other acquisition of securities at price $ 186.10 per share. | 16 Jan 2024 | 80 | 1,330 (0%) | 0% | 186.1 | 14,888 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 150.50 per share. | 16 Jan 2024 | 8 | 1,250 (0%) | 0% | 150.5 | 1,204 | Common Stock |
| Ellis L. Gary | Director | Grant, award, or other acquisition of securities at price $ 150.50 per share. | 16 Jan 2024 | 8 | 3,147 (0%) | 0% | 150.5 | 1,204 | Common Stock |
| Marilyn Nelson Carlson | Director | Grant, award, or other acquisition of securities at price $ 325.88 per share. | 16 Jan 2024 | 8 | 21,108 (0%) | 0% | 325.9 | 2,607 | Common Stock |
| Ellis L. Gary | Director | Grant, award, or other acquisition of securities at price $ 326.00 per share. | 16 Jan 2024 | 2 | 3,139 (0%) | 0% | 326 | 652 | Common Stock |
| Nelson Marilyn Carlson | Director | Grant, award, or other acquisition of securities at price $ 150.48 per share. | 16 Jan 2024 | 25 | 21,133 (0%) | 0% | 150.5 | 3,762 | Common Stock |
| Carlson Marilyn Nelson | Director | Grant, award, or other acquisition of securities at price $ 186.10 per share. | 16 Jan 2024 | 134 | 21,267 (0%) | 0% | 186.1 | 24,937 | Common Stock |
| Sparks Y. Charisse | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 326.00 per share. | 16 Jan 2024 | 2 | 895 (0%) | 0% | 326 | 652 | Common Stock |
| Tansey M. Casey | Director | Grant, award, or other acquisition of securities at price $ 186.10 per share. | 16 Jan 2024 | 77 | 19,482 (0%) | 0% | 186.1 | 14,330 | Common Stock |
| Tansey Casey M. | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jan 2024 | 500 | 500 (0%) | 0% | 0 | Common Stock | |
| M. Casey Tansey | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jan 2024 | 500 | 19,395 (0%) | 0% | 0 | Common Stock | |
| Charisse Y. Sparks | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 150.33 per share. | 16 Jan 2024 | 3 | 898 (0%) | 0% | 150.3 | 451 | Common Stock |
| Tansey M. Casey | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Jan 2024 | 500 | 19,895 (0%) | 0% | 0 | Common Stock | |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 326.00 per share. | 16 Jan 2024 | 2 | 19,397 (0%) | 0% | 326 | 652 | Common Stock |
| J. Curet Myriam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Dec 2023 | 1,384 | 1,384 (0%) | 0% | 0 | Common Stock | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 13 Oct 2023 | 1,037 | 21,100 (0%) | 0% | 0.9 | 975 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Oct 2023 | 963 | 1,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Oct 2023 | 1,037 | 0 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 150.47 per share. | 13 Oct 2023 | 141 | 19,100 (0%) | 0% | 150.5 | 21,216 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 13 Oct 2023 | 963 | 20,063 (0%) | 0% | 0.9 | 905 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 150.47 per share. | 13 Oct 2023 | 99 | 3,137 (0%) | 0% | 150.5 | 14,897 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 150.47 per share. | 13 Oct 2023 | 99 | 1,423 (0%) | 0% | 150.5 | 14,897 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 150.47 per share. | 13 Oct 2023 | 87 | 20,395 (0%) | 0% | 150.5 | 13,091 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 150.47 per share. | 13 Oct 2023 | 91 | 1,240 (0%) | 0% | 150.5 | 13,693 | Common Stock |
| Charisse Y. Sparks | Director | Grant, award, or other acquisition of securities at price $ 150.48 per share. | 13 Oct 2023 | 25 | 893 (0%) | 0% | 150.5 | 3,762 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.78 per share. | 12 Oct 2023 | 4,175 | 115,629 (0%) | 0% | 147.8 | 616,982 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Oct 2023 | 9,086 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Oct 2023 | 113,698 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Oct 2023 | 63,490 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Oct 2023 | 21,762 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 148.02 per share. | 12 Oct 2023 | 52,411 | 119,804 (0%) | 0% | 148.0 | 7,757,876 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.88 per share. | 12 Oct 2023 | 31,376 | 172,315 (0%) | 0% | 147.9 | 4,639,883 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.88 per share. | 12 Oct 2023 | 10,758 | 117,655 (0%) | 0% | 147.9 | 1,590,893 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 12 Oct 2023 | 9,086 | 203,691 (0%) | 0% | 0.9 | 8,541 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.07 per share. | 12 Oct 2023 | 113,698 | 194,605 (0%) | 0% | 2.1 | 235,355 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.38 per share. | 12 Oct 2023 | 63,490 | 80,907 (0%) | 0% | 10.4 | 659,026 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.38 per share. | 12 Oct 2023 | 21,762 | 128,413 (0%) | 0% | 10.4 | 225,890 | Common Stock |
| Charisse Y. Sparks | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 153.50 per share. | 12 Oct 2023 | 100 | 998 (0%) | 0% | 153.5 | 15,350 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 21 Sep 2023 | 2,000 | 18,959 (0%) | 0% | 0.9 | 1,880 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Sep 2023 | 2,000 | 1,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 2,000 | 3,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 14 Sep 2023 | 2,000 | 16,959 (0%) | 0% | 0.9 | 1,880 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Sep 2023 | 47,992 | 106,651 (0%) | 0% | - | Common Stock | |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Sep 2023 | 47,992 | 106,651 (0%) | 0% | 0 | Common Stock | |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Sep 2023 | 24,720 | 54,934 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Sep 2023 | 23,361 | 51,913 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Sep 2023 | 9,793 | 21,762 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Sep 2023 | 2,499 | 5,553 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Sep 2023 | 11,745 | 26,100 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Sep 2023 | 24,720 | 54,934 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Sep 2023 | 23,361 | 51,913 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Sep 2023 | 9,793 | 21,762 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Sep 2023 | 2,499 | 5,553 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Sep 2023 | 11,745 | 26,100 | - | - | Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Aug 2023 | 2,500 | 19,325 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 28 Aug 2023 | 2,500 | 6,871 (0%) | 0% | 0.9 | 2,350 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Aug 2023 | 3,224 | 104,560 (0%) | 0% | 0 | Common Stock | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Aug 2023 | 15 | 51,913 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Aug 2023 | 938 | 64,062 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 71.00 per share. | 23 Aug 2023 | 938 | 107,769 (0%) | 0% | 71 | 66,598 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.13 per share. | 23 Aug 2023 | 15 | 107,784 (0%) | 0% | 42.1 | 632 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Aug 2023 | 2,000 | 5,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 21 Aug 2023 | 2,000 | 14,959 (0%) | 0% | 0.9 | 1,880 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2023 | 2,000 | 7,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 10 Aug 2023 | 2,000 | 12,959 (0%) | 0% | 0.9 | 1,880 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 07 Aug 2023 | 2,000 | 10,959 (0%) | 0% | 0.9 | 1,880 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Aug 2023 | 2,000 | 9,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Aug 2023 | 2,000 | 11,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 04 Aug 2023 | 2,000 | 8,959 (0%) | 0% | 0.9 | 1,880 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 290.48 per share. | 31 Jul 2023 | 29 | 9,352 (0%) | 0% | 290.5 | 8,424 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 290.47 per share. | 31 Jul 2023 | 500 | 8,852 (0%) | 0% | 290.5 | 145,235 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 31 Jul 2023 | 1,000 | 9,381 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jul 2023 | 1,000 | 4,296 | - | - | Stock Option (Right to Buy) | |
| Charisse Y. Sparks | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2023 | 4,452 | 4,452 | - | - | Employee Stock Option (Right to Buy) | |
| Carlton Weatherby | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2023 | 4,452 | 4,452 | - | - | Employee Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 24 Jul 2023 | 1,000 | 8,910 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jul 2023 | 1,000 | 5,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 304.99 per share. | 24 Jul 2023 | 500 | 8,381 (0%) | 0% | 305.0 | 152,495 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 305.00 per share. | 24 Jul 2023 | 29 | 8,881 (0%) | 0% | 305 | 8,845 | Common Stock |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jul 2023 | 2,000 | 13,037 | - | - | Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 24 Jul 2023 | 2,000 | 6,959 (0%) | 0% | 0.9 | 1,880 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 17 Jul 2023 | 1,000 | 8,439 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jul 2023 | 1,000 | 6,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 326.84 per share. | 17 Jul 2023 | 500 | 7,910 (0%) | 0% | 326.8 | 163,420 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 326.83 per share. | 17 Jul 2023 | 29 | 8,410 (0%) | 0% | 326.8 | 9,478 | Common Stock |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 325.91 per share. | 17 Jul 2023 | 65 | 4,959 (0%) | 0% | 325.9 | 21,184 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 325.91 per share. | 17 Jul 2023 | 46 | 3,038 (0%) | 0% | 325.9 | 14,992 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 325.91 per share. | 17 Jul 2023 | 46 | 1,324 (0%) | 0% | 325.9 | 14,992 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 325.90 per share. | 17 Jul 2023 | 40 | 20,308 (0%) | 0% | 325.9 | 13,036 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 325.90 per share. | 17 Jul 2023 | 42 | 1,149 (0%) | 0% | 325.9 | 13,688 | Common Stock |
| Charisse Y. Sparks | Director | Grant, award, or other acquisition of securities at price $ 325.90 per share. | 17 Jul 2023 | 40 | 868 (0%) | 0% | 325.9 | 13,036 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 310.41 per share. | 10 Jul 2023 | 29 | 7,939 (0%) | 0% | 310.4 | 9,002 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Jul 2023 | 1,000 | 7,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 310.42 per share. | 10 Jul 2023 | 500 | 7,439 (0%) | 0% | 310.4 | 155,210 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 10 Jul 2023 | 1,000 | 7,968 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 322.10 per share. | 03 Jul 2023 | 29 | 7,468 (0%) | 0% | 322.1 | 9,341 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jul 2023 | 1,000 | 8,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 322.09 per share. | 03 Jul 2023 | 500 | 6,968 (0%) | 0% | 322.1 | 161,045 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 03 Jul 2023 | 1,000 | 7,497 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 315.86 per share. | 26 Jun 2023 | 29 | 6,997 (0%) | 0% | 315.9 | 9,160 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jun 2023 | 1,000 | 9,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 315.87 per share. | 26 Jun 2023 | 500 | 6,497 (0%) | 0% | 315.9 | 157,935 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 26 Jun 2023 | 1,000 | 7,026 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 307.64 per share. | 20 Jun 2023 | 500 | 6,026 (0%) | 0% | 307.6 | 153,820 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 20 Jun 2023 | 1,000 | 6,555 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 307.66 per share. | 20 Jun 2023 | 29 | 6,526 (0%) | 0% | 307.7 | 8,922 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Jun 2023 | 1,000 | 10,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jun 2023 | 1,000 | 11,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 309.03 per share. | 12 Jun 2023 | 500 | 5,555 (0%) | 0% | 309.0 | 154,515 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 309.03 per share. | 12 Jun 2023 | 29 | 6,055 (0%) | 0% | 309.0 | 8,962 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 12 Jun 2023 | 1,000 | 6,084 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 05 Jun 2023 | 1,000 | 5,613 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2023 | 1,000 | 12,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 305.69 per share. | 05 Jun 2023 | 500 | 5,084 (0%) | 0% | 305.7 | 152,845 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 305.69 per share. | 05 Jun 2023 | 29 | 5,584 (0%) | 0% | 305.7 | 8,865 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 294.90 per share. | 30 May 2023 | 500 | 4,613 (0%) | 0% | 294.9 | 147,450 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 294.90 per share. | 30 May 2023 | 29 | 5,113 (0%) | 0% | 294.9 | 8,552 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 30 May 2023 | 1,000 | 5,142 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 May 2023 | 1,000 | 13,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 May 2023 | 1,000 | 14,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 22 May 2023 | 1,000 | 4,671 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 307.52 per share. | 22 May 2023 | 500 | 4,142 (0%) | 0% | 307.5 | 153,760 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 307.52 per share. | 22 May 2023 | 29 | 4,642 (0%) | 0% | 307.5 | 8,918 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 15 May 2023 | 1,000 | 4,200 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 1,000 | 15,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 293.91 per share. | 15 May 2023 | 500 | 3,671 (0%) | 0% | 293.9 | 146,955 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 293.90 per share. | 15 May 2023 | 29 | 4,171 (0%) | 0% | 293.9 | 8,523 | Common Stock |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 May 2023 | 4,525 | 15,475 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 71.00 per share. | 12 May 2023 | 4,525 | 8,896 (0%) | 0% | 71 | 321,275 | Common Stock |
| Steven Jandrich | VP, Human Resources | Sale of securities on an exchange or to another person at price $ 291.85 per share. | 12 May 2023 | 1,293 | 7,603 (0%) | 0% | 291.8 | 377,362 | Common Stock |
| Steven Jandrich | VP, Human Resources | Sale of securities on an exchange or to another person at price $ 292.84 per share. | 12 May 2023 | 2,007 | 5,596 (0%) | 0% | 292.8 | 587,730 | Common Stock |
| Steven Jandrich | VP, Human Resources | Sale of securities on an exchange or to another person at price $ 293.89 per share. | 12 May 2023 | 1,225 | 4,371 (0%) | 0% | 293.9 | 360,015 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 280.00 per share. | 08 May 2023 | 500 | 3,200 (0%) | 0% | 280 | 140,000 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2023 | 1,000 | 16,296 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.00 per share. | 08 May 2023 | 1,000 | 3,729 (0%) | 0% | 16 | 16,000 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 280.00 per share. | 08 May 2023 | 29 | 3,700 (0%) | 0% | 280 | 8,120 | Common Stock |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2023 | 1,727 | 3,705 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 08 May 2023 | 1,727 | 6,098 (0%) | 0% | 42.1 | 72,793 | Common Stock |
| Steven Jandrich | VP, Human Resources | Sale of securities on an exchange or to another person at price $ 280.12 per share. | 08 May 2023 | 1,727 | 4,371 (0%) | 0% | 280.1 | 483,767 | Common Stock |
| Jerry C. Griffin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 2,729 (0%) | 0% | 0 | Common Stock | |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 4,894 (0%) | 0% | 0 | Common Stock | |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 2,992 (0%) | 0% | 0 | Common Stock | |
| Dana G. Mead | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 20,669 (0%) | 0% | 0 | Common Stock | |
| Shawn T. McCormick | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 12,187 (0%) | 0% | 0 | Common Stock | |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 1,278 (0%) | 0% | 0 | Common Stock | |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 20,268 (0%) | 0% | 0 | Common Stock | |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 1,107 (0%) | 0% | 0 | Common Stock | |
| Cynthia B. Burks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 669 (0%) | 0% | 0 | Common Stock | |
| Charisse Y. Sparks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2023 | 669 | 828 (0%) | 0% | 0 | Common Stock | |
| Steven Jandrich | VP, Human Resources | Sale of securities on an exchange or to another person at price $ 270.24 per share. | 25 Apr 2023 | 5,499 | 6,872 (0%) | 0% | 270.2 | 1,486,050 | Common Stock |
| Steven Jandrich | VP, Human Resources | Sale of securities on an exchange or to another person at price $ 271.20 per share. | 25 Apr 2023 | 401 | 6,471 (0%) | 0% | 271.2 | 108,751 | Common Stock |
| Steven Jandrich | VP, Human Resources | Sale of securities on an exchange or to another person at price $ 273.03 per share. | 25 Apr 2023 | 2,100 | 4,371 (0%) | 0% | 273.0 | 573,363 | Common Stock |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Apr 2023 | 8,000 | 5,432 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 25 Apr 2023 | 8,000 | 12,371 (0%) | 0% | 42.2 | 337,200 | Common Stock |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 231.77 per share. | 10 Apr 2023 | 91 | 4,225 (0%) | 0% | 231.8 | 21,091 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 231.77 per share. | 10 Apr 2023 | 64 | 2,323 (0%) | 0% | 231.8 | 14,833 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 231.77 per share. | 10 Apr 2023 | 64 | 609 (0%) | 0% | 231.8 | 14,833 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 231.77 per share. | 10 Apr 2023 | 56 | 19,599 (0%) | 0% | 231.8 | 12,979 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 231.76 per share. | 10 Apr 2023 | 59 | 438 (0%) | 0% | 231.8 | 13,674 | Common Stock |
| Charisse Y. Sparks | Director | Grant, award, or other acquisition of securities at price $ 231.77 per share. | 10 Apr 2023 | 56 | 159 (0%) | 0% | 231.8 | 12,979 | Common Stock |
| Shawn T. McCormick | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Mar 2023 | 4,000 | 3,519 | - | - | Stock Option (Right to Buy) | |
| Shawn T. McCormick | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 17 Mar 2023 | 4,000 | 11,518 (0%) | 0% | 0.9 | 3,760 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2023 | 4,387 | 8,000 | - | - | Employee Stock Option (Right to Buy) | |
| John C. Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.07 per share. | 08 Mar 2023 | 4,387 | 13,478 (0%) | 0% | 2.1 | 9,081 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 01 Mar 2023 | 10,000 | 10,304 (0%) | 0% | 0.9 | 9,400 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2023 | 10,000 | 11,090 | - | - | Stock Option (Right to Buy) | |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 263.37 per share. | 01 Mar 2023 | 1,566 | 304 (0%) | 0% | 263.4 | 412,437 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 261.54 per share. | 01 Mar 2023 | 900 | 1,870 (0%) | 0% | 261.5 | 235,386 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 26074.00 per share. | 01 Mar 2023 | 3,135 | 2,770 (0%) | 0% | 26074 | 81,741,990 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 259.74 per share. | 01 Mar 2023 | 3,222 | 5,905 (0%) | 0% | 259.7 | 836,882 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 258.62 per share. | 01 Mar 2023 | 1,177 | 9,127 (0%) | 0% | 258.6 | 304,396 | Common Stock |
| Steven Jandrich | VP, Human Resources | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2023 | 128 | 4,371 (0%) | 0% | 0 | Common Stock | |
| Steven Jandrich | VP, Human Resources | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2023 | 128 | 478 (0%) | 0% | 0 | Common Stock | |
| Steven Jandrich | VP, Human Resources | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2023 | 128 | 478 (0%) | 0% | 0 | Common Stock | |
| Steven Jandrich | VP, Human Resources | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2023 | 128 | 4,499 (0%) | 0% | 0 | Common Stock | |
| Steven Jandrich | VP, Human Resources | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2023 | 128 | 4,627 (0%) | 0% | 0 | Common Stock | |
| Philip J. Ebeling | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 194.82 per share. | 16 Feb 2023 | 7,000 | 7,243 (0%) | 0% | 194.8 | 1,363,740 | Common Stock |
| Philip J. Ebeling | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2023 | 7,000 | 10,300 | - | - | Employee Stock Option (Right to Buy) | |
| Philip J. Ebeling | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 275.00 per share. | 16 Feb 2023 | 7,000 | 243 (0%) | 0% | 275 | 1,925,000 | Common Stock |
| Bryan K. Phillips | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 5,450 | 5,450 | - | - | Employee Stock Option (Right to Buy) | |
| Philip J. Ebeling | Chief Operating Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Feb 2023 | 167 | 243 (0%) | 0% | 0 | Common Stock | |
| Philip J. Ebeling | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 5,450 | 5,450 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 5,450 | 5,450 | - | - | Employee Stock Option (Right to Buy) | |
| Randall A. Ban | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 5,450 | 5,450 | - | - | Employee Stock Option (Right to Buy) | |
| Richard J. Buchholz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 5,450 | 5,450 | - | - | Employee Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 20,439 | 20,439 | - | - | Employee Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 275.05 per share. | 10 Feb 2023 | 2,619 | 9,728 (0%) | 0% | 275.1 | 720,356 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 5,450 | 5,450 | - | - | Employee Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 275.12 per share. | 08 Feb 2023 | 7,028 | 12,347 (0%) | 0% | 275.1 | 1,933,543 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Feb 2023 | 2,000 | 20,641 (0%) | 0% | 0 | Common Stock | |
| Timothy P. Herbert | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 275.00 per share. | 08 Feb 2023 | 3,500 | 19,375 (0%) | 0% | 275 | 962,500 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 249.08 per share. | 06 Feb 2023 | 490 | 14,601 (0%) | 0% | 249.1 | 122,049 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 270.00 per share. | 06 Feb 2023 | 1,560 | 9,091 (0%) | 0% | 270 | 421,200 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 251.72 per share. | 06 Feb 2023 | 361 | 11,591 (0%) | 0% | 251.7 | 90,871 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 265.00 per share. | 06 Feb 2023 | 940 | 10,651 (0%) | 0% | 265 | 249,100 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 249.91 per share. | 06 Feb 2023 | 1,700 | 12,901 (0%) | 0% | 249.9 | 424,847 | Common Stock |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 250.73 per share. | 06 Feb 2023 | 949 | 11,952 (0%) | 0% | 250.7 | 237,943 | Common Stock |
| Bryan K. Phillips | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 253.24 per share. | 29 Jan 2023 | 205 | 1,960 (0%) | 0% | 253.2 | 51,914 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jan 2023 | 117 | 17,849 | - | - | Employee Stock Option (Right to Buy) | |
| Richard J. Buchholz | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.38 per share. | 25 Jan 2023 | 3,290 | 37,677 (0%) | 0% | 10.4 | 34,150 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 71.00 per share. | 25 Jan 2023 | 117 | 37,794 (0%) | 0% | 71 | 8,307 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.15 per share. | 25 Jan 2023 | 2,693 | 40,487 (0%) | 0% | 42.2 | 113,510 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jan 2023 | 3,290 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Richard J. Buchholz | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jan 2023 | 2,693 | 7,159 | - | - | Employee Stock Option (Right to Buy) | |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 23 Jan 2023 | 500 | 4,755 (0%) | 0% | 0.9 | 470 | Common Stock |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Jan 2023 | 500 | 21,825 | - | - | Employee Stock Option (Right to Buy) | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Jan 2023 | 100 | 1,225 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Jan 2023 | 100 | 1,225 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Jan 2023 | 400 | 46,887 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 250.03 per share. | 11 Jan 2023 | 11,977 | 34,387 (0%) | 0% | 250.0 | 2,994,609 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 250.00 per share. | 11 Jan 2023 | 523 | 46,364 (0%) | 0% | 250 | 130,750 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Jan 2023 | 100 | 1,225 (0%) | 0% | 0 | Common Stock | |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Jan 2023 | 100 | 1,225 (0%) | 0% | 0 | Common Stock | |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 248.31 per share. | 10 Jan 2023 | 85 | 4,134 (0%) | 0% | 248.3 | 21,106 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 248.32 per share. | 10 Jan 2023 | 60 | 2,259 (0%) | 0% | 248.3 | 14,899 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 248.32 per share. | 10 Jan 2023 | 60 | 545 (0%) | 0% | 248.3 | 14,899 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 248.31 per share. | 10 Jan 2023 | 52 | 19,543 (0%) | 0% | 248.3 | 12,912 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 248.31 per share. | 10 Jan 2023 | 55 | 379 (0%) | 0% | 248.3 | 13,657 | Common Stock |
| Charisse Y. Sparks | Director | Grant, award, or other acquisition of securities at price $ 248.31 per share. | 10 Jan 2023 | 52 | 103 (0%) | 0% | 248.3 | 12,912 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 255.98 per share. | 03 Jan 2023 | 156 | 304 (0%) | 0% | 256.0 | 39,933 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 253.79 per share. | 03 Jan 2023 | 1,056 | 460 (0%) | 0% | 253.8 | 268,002 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 252.71 per share. | 03 Jan 2023 | 3,788 | 1,516 (0%) | 0% | 252.7 | 957,265 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 251.64 per share. | 03 Jan 2023 | 2,600 | 5,304 (0%) | 0% | 251.6 | 654,264 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 250.62 per share. | 03 Jan 2023 | 2,400 | 7,904 (0%) | 0% | 250.6 | 601,488 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 03 Jan 2023 | 10,000 | 10,304 (0%) | 0% | 0.9 | 9,400 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2023 | 10,000 | 21,090 | - | - | Stock Option (Right to Buy) | |
| John C. Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 256.00 per share. | 03 Jan 2023 | 1,170 | 15,091 (0%) | 0% | 256 | 299,520 | Common Stock |
| John Rondoni | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 251.72 per share. | 19 Dec 2022 | 678 | 16,230 (0%) | 0% | 251.7 | 170,666 | Common Stock |
| Marilyn Carlson Nelson | Director | Sale of securities on an exchange or to another person at price $ 248.00 per share. | 16 Dec 2022 | 1,662 | 56,130 (0%) | 0% | 248 | 412,176 | Common Stock |
| Marilyn Carlson Nelson | Director | Sale of securities on an exchange or to another person at price $ 243.50 per share. | 16 Dec 2022 | 15,058 | 57,792 (0%) | 0% | 243.5 | 3,666,623 | Common Stock |
| Marilyn Carlson Nelson | Director | Sale of securities on an exchange or to another person at price $ 250.00 per share. | 16 Dec 2022 | 5,211 | 50,919 (0%) | 0% | 250 | 1,302,750 | Common Stock |
| Marilyn Carlson Nelson | Director | Sale of securities on an exchange or to another person at price $ 240.03 per share. | 16 Dec 2022 | 2,033 | 74,097 (0%) | 0% | 240.0 | 487,981 | Common Stock |
| Marilyn Carlson Nelson | Director | Sale of securities on an exchange or to another person at price $ 241.63 per share. | 16 Dec 2022 | 1,247 | 72,850 (0%) | 0% | 241.6 | 301,313 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 236.64 per share. | 02 Dec 2022 | 642 | 2,834 (0%) | 0% | 236.6 | 151,923 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 235.29 per share. | 02 Dec 2022 | 1,954 | 3,476 (0%) | 0% | 235.3 | 459,757 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 02 Dec 2022 | 10,333 | 10,618 (0%) | 0% | 0.9 | 9,713 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 234.68 per share. | 02 Dec 2022 | 5,188 | 5,430 (0%) | 0% | 234.7 | 1,217,520 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Dec 2022 | 5,000 | 31,090 | - | - | Stock Option (Right to Buy) | |
| Randall A. Ban | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Dec 2022 | 5,333 | 200 | - | - | Stock Option (Right to Buy) | |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 239.16 per share. | 02 Dec 2022 | 1,149 | 285 (0%) | 0% | 239.2 | 274,795 | Common Stock |
| Randall A. Ban | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 238.05 per share. | 02 Dec 2022 | 1,400 | 1,434 (0%) | 0% | 238.1 | 333,270 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 11 Nov 2022 | 3,759 | 11,277 (0%) | 0% | 0.9 | 3,533 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Nov 2022 | 3,759 | 0 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Nov 2022 | 7,518 | 0 | - | - | Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 222.12 per share. | 11 Nov 2022 | 3,266 | 2,060 (0%) | 0% | 222.1 | 725,444 | Common Stock |
| Jerry C. Griffin | Director | Sale of securities on an exchange or to another person at price $ 221.04 per share. | 11 Nov 2022 | 5,951 | 5,326 (0%) | 0% | 221.0 | 1,315,409 | Common Stock |
| Jerry C. Griffin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 11 Nov 2022 | 7,518 | 7,518 (0%) | 0% | 0.9 | 7,067 | Common Stock |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 17 Oct 2022 | 750 | 4,255 (0%) | 0% | 0.9 | 705 | Common Stock |
| Steven Jandrich | VP, Human Resources | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Oct 2022 | 750 | 22,325 | - | - | Employee Stock Option (Right to Buy) | |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 168.98 per share. | 11 Oct 2022 | 129 | 4,049 (0%) | 0% | 169.0 | 21,798 | Common Stock |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 168.98 per share. | 11 Oct 2022 | 88 | 2,199 (0%) | 0% | 169.0 | 14,870 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 168.98 per share. | 11 Oct 2022 | 85 | 485 (0%) | 0% | 169.0 | 14,363 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 168.98 per share. | 11 Oct 2022 | 81 | 19,491 (0%) | 0% | 169.0 | 13,687 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 11 Oct 2022 | 41,216 | 159,895 (0%) | 0% | 0.9 | 38,743 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.38 per share. | 11 Oct 2022 | 27,529 | 118,679 (0%) | 0% | 10.4 | 285,751 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 42.14 per share. | 11 Oct 2022 | 42 | 159,937 (0%) | 0% | 42.1 | 1,770 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Oct 2022 | 42 | 84,958 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Oct 2022 | 41,216 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Oct 2022 | 27,529 | 85,252 | - | - | Stock Option (Right to Buy) | |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 168.98 per share. | 11 Oct 2022 | 81 | 324 (0%) | 0% | 169.0 | 13,687 | Common Stock |
| Charisse Y. Sparks | Director | Grant, award, or other acquisition of securities at price $ 168.98 per share. | 11 Oct 2022 | 51 | 51 (0%) | 0% | 169.0 | 8,618 | Common Stock |
| John Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Sep 2022 | 6,218 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| John Rondoni | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.94 per share. | 23 Sep 2022 | 6,218 | 16,828 (0%) | 0% | 0.9 | 5,845 | Common Stock |
| Cynthia B. Burks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 1,823 | 1,823 | - | - | Employee Stock Option (Right to Buy) | |
| Charisse Y. Sparks | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jul 2022 | 1,823 | 1,823 | - | - | Employee Stock Option (Right to Buy) | |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 193.86 per share. | 11 Jul 2022 | 77 | 2,111 (0%) | 0% | 193.9 | 14,927 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 193.87 per share. | 11 Jul 2022 | 67 | 400 (0%) | 0% | 193.9 | 12,989 | Common Stock |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 193.86 per share. | 11 Jul 2022 | 119 | 3,920 (0%) | 0% | 193.9 | 23,069 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 193.86 per share. | 11 Jul 2022 | 77 | 19,410 (0%) | 0% | 193.9 | 14,927 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 193.86 per share. | 11 Jul 2022 | 70 | 243 (0%) | 0% | 193.9 | 13,570 | Common Stock |
| John Rondoni | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 7,529 | 7,529 | - | - | Employee Stock Option (Right to Buy) | |
| Jerry C. Griffin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Dana G. Mead | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Shawn T. McCormick | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2022 | 1,243 | 1,243 | - | - | Stock Option (right to buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Apr 2022 | 8,196 | 0 | - | - | Stock Option (Right to Buy) | |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.47 per share. | 18 Apr 2022 | 9,221 | 14,445 (0%) | 0% | 1.5 | 13,555 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.14 per share. | 18 Apr 2022 | 8,196 | 22,641 (0%) | 0% | 1.1 | 9,343 | Common Stock |
| Timothy P. Herbert | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Apr 2022 | 9,221 | 0 | - | - | Stock Option (Right to Buy) | |
| Gary L. Ellis | Director | Grant, award, or other acquisition of securities at price $ 254.08 per share. | 08 Apr 2022 | 59 | 2,034 (0%) | 0% | 254.1 | 14,991 | Common Stock |
| Shelley G. Broader | Director | Grant, award, or other acquisition of securities at price $ 254.08 per share. | 08 Apr 2022 | 51 | 333 (0%) | 0% | 254.1 | 12,958 | Common Stock |
| Marilyn Carlson Nelson | Director | Grant, award, or other acquisition of securities at price $ 254.08 per share. | 08 Apr 2022 | 91 | 3,801 (0%) | 0% | 254.1 | 23,121 | Common Stock |
| Casey M. Tansey | Director | Grant, award, or other acquisition of securities at price $ 254.08 per share. | 08 Apr 2022 | 59 | 19,333 (0%) | 0% | 254.1 | 14,991 | Common Stock |
| Georgia Garinois-Melenikiotou | Director | Grant, award, or other acquisition of securities at price $ 254.07 per share. | 08 Apr 2022 | 54 | 173 (0%) | 0% | 254.1 | 13,720 | Common Stock |
| Marilyn Carlson Nelson | Director | Sale of securities on an exchange or to another person at price $ 270.00 per share. | 01 Apr 2022 | 5,000 | 76,130 (0%) | 0% | 270 | 1,350,000 | Common Stock |
| Marilyn Carlson Nelson | Director | Sale of securities on an exchange or to another person at price $ 265.00 per share. | 01 Apr 2022 | 5,000 | 81,130 (0%) | 0% | 265 | 1,325,000 | Common Stock |
| Richard J. Buchholz | Chief Financial Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Apr 2022 | 250 | 62,426 (0%) | 0% | 0 | Common Stock |