Insider Trading disclosures for Incyte Corp.

The latest disclosure was made by Sheila A Denton in Incyte Corp. where a trade of 599 Common Stock done at an average price of $58.1 was reported to US exchanges on March 4, 2025.

Insider trading is the trading of a company’s securities by individuals with access to confidential or material non-public information about the company. A company is required to report trading by corporate officers, directors, or other company members with significant access to privileged information to the Securities and Exchange Commission (SEC).

Client Name	Client Category	Action	Reported to Exchange	Quantity	Post Transaction Holding	Traded %	Avg. Price	Value	Security Type
Sheila A Denton	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.06 per share.	04 Mar 2025	599	26,447 (0%)	0%	58.1	34,778	Common Stock
Sheila A Denton	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Mar 2025	599	18,552	-		-	Employee Stock Option (right to buy)
Sheila A Denton	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 69.99 per share.	04 Mar 2025	599	25,848 (0%)	0%	70.0	41,924	Common Stock
Sheila A Denton	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Feb 2025	9,574	19,151	-		-	Employee Stock Option (right to buy)
Sheila A Denton	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 74.08 per share.	26 Feb 2025	4,495	25,848 (0%)	0%	74.1	332,990	Common Stock
Sheila A Denton	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 74.07 per share.	26 Feb 2025	9,574	30,343 (0%)	0%	74.1	709,146	Common Stock
Sheila A Denton	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.06 per share.	26 Feb 2025	9,574	39,917 (0%)	0%	58.1	555,866	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2025	10,552	81,515 (0%)	0%		0	Common Stock
Lee Heeson	EVP, Head of Incyte Intl	Grant, award, or other acquisition of securities at price $ 0.00 per share.	31 Jan 2025	6,331	32,778 (0%)	0%		0	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 73.47 per share.	21 Jan 2025	429	70,963 (0%)	0%	73.5	31,519	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	14,772	14,772	-		-	Employee Stock Option (right to buy)
Pablo J. Cagnoni	President, R&D	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	40,289	40,289	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	25,516	25,516	-		-	Employee Stock Option (right to buy)
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	55,510	55,510	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	20,144	20,144	-		-	Employee Stock Option (right to buy)
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	14,772	14,772	-		-	Employee Stock Option (right to buy)
Steven H. Stein	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 72.69 per share.	17 Jan 2025	12,352	66,967 (0%)	0%	72.7	897,867	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	28,202	28,202	-		-	Employee Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	3,432	3,432	-		-	Employee Stock Option (right to buy)
Sheila A Denton	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2025	12,086	12,086	-		-	Employee Stock Option (right to buy)
Matteo Trotta	EVP, GM, Dermatology US		17 Jan 2025	5,371	5,371	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 72.46 per share.	15 Jan 2025	3,672	91,525 (0%)	0%	72.5	266,073	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 72.46 per share.	15 Jan 2025	3,158	53,374 (0%)	0%	72.5	228,829	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 72.46 per share.	15 Jan 2025	10,692	79,319 (0%)	0%	72.5	774,742	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 72.46 per share.	15 Jan 2025	908	71,392 (0%)	0%	72.5	65,794	Common Stock
Mohamed Khairie Issa	EVP, Head of US Oncology		06 Jan 2025	48,671	48,671 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 69.07 per share.	31 Dec 2024	331	19,713 (0%)	0%	69.1	22,862	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 69.07 per share.	31 Dec 2024	339	17,071 (0%)	0%	69.1	23,415	Common Stock
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 69.31 per share.	13 Dec 2024	650	23,312 (0%)	0%	69.3	45,052	Common Stock
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 70.64 per share.	13 Dec 2024	650	23,962 (0%)	0%	70.6	45,916	Common Stock
Paula J. Swain	EVP, Human Resources	Payment of exercise price or tax liability using portion of securities received from the company at price $ 72.11 per share.	09 Dec 2024	873	85,203 (0%)	0%	72.1	62,952	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 72.11 per share.	09 Dec 2024	1,510	56,532 (0%)	0%	72.1	108,886	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 75.37 per share.	29 Nov 2024	5,683	30,658 (0%)	0%	75.4	428,328	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 75.60 per share.	29 Nov 2024	360	36,341 (0%)	0%	75.6	27,216	Common Stock
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 72.27 per share.	06 Nov 2024	1,424	59,466 (0%)	0%	72.3	102,912	Common Stock
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Nov 2024	2,256	0	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Nov 2024	1,424	0	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 78.21 per share.	06 Nov 2024	2,256	58,042 (0%)	0%	78.2	176,442	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 82.00 per share.	06 Nov 2024	1,424	60,298 (0%)	0%	82	116,768	Common Stock
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 68.62 per share.	06 Nov 2024	2,256	61,722 (0%)	0%	68.6	154,807	Common Stock
Sheila A Denton	EVP & General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 67.63 per share.	02 Oct 2024	2,136	30,343 (0%)	0%	67.6	144,458	Common Stock
Lee Heeson	EVP, Head of Incyte Intl		01 Oct 2024	26,447	26,447 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 66.10 per share.	30 Sep 2024	368	19,382 (0%)	0%	66.1	24,325	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 66.10 per share.	30 Sep 2024	378	16,732 (0%)	0%	66.1	24,986	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		12 Sep 2024	7,333	36,390 (0%)	0%	62.4	457,359	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		12 Sep 2024	1,117	43,723 (0%)	0%	62.3	69,589	Common Stock
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 63.37 per share.	12 Sep 2024	382	24,443 (0%)	0%	63.4	24,207	Common Stock
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 62.94 per share.	12 Sep 2024	572	24,825 (0%)	0%	62.9	36,002	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 60.63 per share.	12 Aug 2024	11,608	90,011 (0%)	0%	60.6	703,793	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 70.00 per share.	25 Jul 2024	15,571	36,701 (0%)	0%	70	1,089,970	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	16,284	16,284	-		-	Employee Stock Option (right to buy)
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	7,278	86,625 (0%)	0%		0	Common Stock
Paula J. Swain	EVP, Human Resources	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	549	86,076 (0%)	0%	64.2	35,273	Common Stock
Pablo J. Cagnoni	President, R&D	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	749	221,170 (0%)	0%	64.2	48,123	Common Stock
Pablo J. Cagnoni	President, R&D	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	19,851	221,919 (0%)	0%		0	Common Stock
Pablo J. Cagnoni	President, R&D	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	44,411	44,411	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	12,572	96,145 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	28,127	28,127	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	948	95,197 (0%)	0%	64.3	60,909	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	4,961	496,674 (0%)	0%	64.2	318,744	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	41,025	501,635 (0%)	0%		0	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	61,189	61,189	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	22,205	22,205	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 64.19 per share.	15 Jul 2024	1,306	58,042 (0%)	0%	64.2	83,832	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	1,111	59,348 (0%)	0%	64.3	71,382	Common Stock
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	9,925	60,459 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	549	52,272 (0%)	0%	64.2	35,273	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	16,284	16,284	-		-	Employee Stock Option (right to buy)
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	7,278	52,821 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	1,555	101,619 (0%)	0%	64.3	99,909	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	31,088	31,088	-		-	Employee Stock Option (right to buy)
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	13,895	103,174 (0%)	0%		0	Common Stock
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	3,783	3,783	-		-	Employee Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	5,073	25,863 (0%)	0%		0	Common Stock
Thomas Tray	Principal Accounting Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.25 per share.	15 Jul 2024	466	25,397 (0%)	0%	64.3	29,941	Common Stock
Sheila A Denton	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	13,323	13,323	-		-	Employee Stock Option (right to buy)
Sheila A Denton	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jul 2024	5,955	32,479 (0%)	0%		0	Common Stock
Matteo Trotta	EVP, GM, Dermatology US		15 Jul 2024	5,921	5,921	-		-	Employee Stock Option (right to buy)
Matteo Trotta	EVP, GM, Dermatology US		15 Jul 2024	2,646	10,474 (0%)	0%		0	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 60.00 per share.	09 Jul 2024	8,148	50,534 (0%)	0%	60	488,880	Common Stock
Paula J. Swain	EVP, Human Resources	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.02 per share.	02 Jul 2024	5,560	79,347 (0%)	0%	59.0	328,151	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.02 per share.	02 Jul 2024	6,870	83,573 (0%)	0%	59.0	405,467	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.02 per share.	02 Jul 2024	41,723	460,610 (0%)	0%	59.0	2,462,491	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.02 per share.	02 Jul 2024	7,695	58,682 (0%)	0%	59.0	454,159	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.02 per share.	02 Jul 2024	5,706	45,543 (0%)	0%	59.0	336,768	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.02 per share.	02 Jul 2024	8,316	89,279 (0%)	0%	59.0	490,810	Common Stock
Thomas Tray	Principal Accounting Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.02 per share.	02 Jul 2024	844	20,790 (0%)	0%	59.0	49,813	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 60.62 per share.	28 Jun 2024	399	19,014 (0%)	0%	60.6	24,187	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 60.62 per share.	28 Jun 2024	409	16,354 (0%)	0%	60.6	24,794	Common Stock
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	12,517	12,517	-		-	Non Qualfied Stock Option (right to buy)
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	2,830	18,323 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	2,830	18,615 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	12,517	12,517	-		-	Non Qualfied Stock Option (right to buy)
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	12,517	12,517	-		-	Non Qualfied Stock Option (right to buy)
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	2,830	16,808 (0%)	0%		0	Common Stock
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	2,830	8,734 (0%)	0%		0	Common Stock
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	12,517	12,517	-		-	Non Qualfied Stock Option (right to buy)
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	2,830	15,945 (0%)	0%		0	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	12,517	12,517	-		-	Non Qualfied Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 60.00 per share.	12 Jun 2024	19,164	66,377 (0%)	0%	60	1,149,840	Common Stock
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	12,517	12,517	-		-	Non Qualfied Stock Option (right to buy)
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	2,830	10,823 (0%)	0%		0	Common Stock
Susanne Schaffert	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	2,830	5,720 (0%)	0%		0	Common Stock
Susanne Schaffert	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Jun 2024	12,517	12,517	-		-	Non Qualfied Stock Option (right to buy)
Susanne Schaffert	Director	Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.94 per share.	12 Jun 2024	752	2,890 (0%)	0%	59.9	45,075	Common Stock
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 58.91 per share.	06 Jun 2024	1,093	21,634 (0%)	0%	58.9	64,389	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 56.97 per share.	28 Mar 2024	403	15,785 (0%)	0%	57.0	22,959	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 56.97 per share.	28 Mar 2024	413	13,115 (0%)	0%	57.0	23,529	Common Stock
Matteo Trotta	EVP, GM, Dermatology US		25 Mar 2024	21,868	21,868	-		-	Employee Stock Option (right to buy)
Matteo Trotta	EVP, GM, Dermatology US		25 Mar 2024	7,828	7,828 (0%)	0%		0	Common Stock
Hoppenot Herve	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Feb 2024	41,577	502,333 (0%)	0%		0	Common Stock
Stamoulis Christiana	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Feb 2024	7,377	89,983 (0%)	0%		0	Common Stock
H. Steven Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Feb 2024	7,377	97,595 (0%)	0%		0	Common Stock
Paula Swain J.	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Feb 2024	7,377	84,907 (0%)	0%		0	Common Stock
P. Flannelly Barry	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Feb 2024	7,377	85,080 (0%)	0%		0	Common Stock
Iyengar K. Vijay	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Feb 2024	7,377	50,789 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.84 per share.	12 Feb 2024	387	82,606 (0%)	0%	57.8	22,384	Common Stock
Morrissey Michael James	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 61.50 per share.	22 Jan 2024	108	72,300 (0%)	0%	61.5	6,642	Common Stock
Elliott Dickinson Jonathan	EVP, General Manager, Europe		22 Jan 2024	108	44,380 (0%)	0%	61.5	6,642	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2024	30,580	30,580	-		-	Employee Stock Option (right to buy)
Michael Morrissey James	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 61.49 per share.	18 Jan 2024	122	72,408 (0%)	0%	61.5	7,502	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2024	16,018	16,018	-		-	Employee Stock Option (right to buy)
Stamoulis Christiana	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2024	27,668	27,668	-		-	Employee Stock Option (right to buy)
Elliott Dickinson Jonathan	EVP, General Manager, Europe		18 Jan 2024	8,114	44,610 (0%)	0%	61.2	496,415	Common Stock
Hoppenot Herve	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2024	97,566	97,566	-		-	Employee Stock Option (right to buy)
Elliott Jonathan Dickinson	EVP, General Manager, Europe		18 Jan 2024	122	44,488 (0%)	0%	61.5	7,502	Common Stock
James Morrissey Michael	EVP, Head of Tech. Operations	Grant, award, or other acquisition of securities at price $ 61.18 per share.	18 Jan 2024	11,359	72,530 (0%)	0%	61.2	694,944	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2024	16,018	16,018	-		-	Employee Stock Option (right to buy)
Flannelly Barry P.	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2024	21,843	21,843	-		-	Employee Stock Option (right to buy)
Pablo Cagnoni J.	President, R&D	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2024	21,843	21,843	-		-	Employee Stock Option (right to buy)
P. Flannelly Barry	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 61.48 per share.	17 Jan 2024	3,675	77,703 (0%)	0%	61.5	225,939	Common Stock
Tray Thomas	Principal Accounting Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 61.48 per share.	17 Jan 2024	1,021	22,415 (0%)	0%	61.5	62,771	Common Stock
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jan 2024	4,530	4,530	-		-	Employee Stock Option (right to buy)
Jonathan Dickinson Elliott	EVP, General Manager, Europe		16 Jan 2024	101	36,496 (0%)	0%	61.5	6,209	Common Stock
Elliott Dickinson Jonathan	EVP, General Manager, Europe		16 Jan 2024	101	36,597 (0%)	0%	61.3	6,195	Common Stock
Morrissey Michael James	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 61.48 per share.	16 Jan 2024	101	61,171 (0%)	0%	61.5	6,209	Common Stock
Morrissey James Michael	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 61.34 per share.	16 Jan 2024	101	61,272 (0%)	0%	61.3	6,195	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 65.51 per share.	03 Jan 2024	7,365	90,218 (0%)	0%	65.5	482,481	Common Stock
Iyengar Vijay K.	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 65.00 per share.	02 Jan 2024	657	43,412 (0%)	0%	65	42,705	Common Stock
Clancy J. Paul	Director	Grant, award, or other acquisition of securities at price $ 62.79 per share.	29 Dec 2023	412	15,382 (0%)	0%	62.8	25,869	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 62.79 per share.	29 Dec 2023	423	12,702 (0%)	0%	62.8	26,560	Common Stock
Tray Thomas	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 57.36 per share.	12 Dec 2023	210	24,503 (0%)	0%	57.4	12,046	Common Stock
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 62.37 per share.	12 Dec 2023	1,067	23,436 (0%)	0%	62.4	66,549	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 63.28 per share.	01 Aug 2023	21,511	97,583 (0%)	0%	63.3	1,361,216	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	14,868	14,868	-		-	Employee Stock Option (right to buy)
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	7,089	85,979 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	12,246	82,993 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	25,682	25,682	-		-	Employee Stock Option (right to buy)
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	43,184	434,856 (0%)	0%		0	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	90,563	90,563	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	20,275	20,275	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	9,668	81,378 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	14,868	14,868	-		-	Employee Stock Option (right to buy)
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	7,089	44,069 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	28,385	28,385	-		-	Employee Stock Option (right to buy)
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	13,535	119,094 (0%)	0%		0	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	9,668	69,724 (0%)	0%		0	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	20,275	20,275	-		-	Employee Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	8,056	58,968 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	16,896	16,896	-		-	Employee Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	4,204	4,204	-		-	Employee Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jul 2023	6,015	24,539 (0%)	0%		0	Common Stock
Paula J. Swain	EVP, Human Resources	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	5,783	78,890 (0%)	0%	62.1	359,009	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	6,073	70,747 (0%)	0%	62.1	377,012	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	43,467	391,672 (0%)	0%	62.1	2,698,431	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	6,304	71,710 (0%)	0%	62.1	391,352	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	6,215	36,980 (0%)	0%	62.1	385,827	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	8,442	105,559 (0%)	0%	62.1	524,079	Common Stock
Maria E. Pasquale	EVP & General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	8,468	60,056 (0%)	0%	62.1	525,693	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	6,044	50,912 (0%)	0%	62.1	375,212	Common Stock
Thomas Tray	Principal Accounting Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.08 per share.	03 Jul 2023	1,136	18,524 (0%)	0%	62.1	70,523	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 62.25 per share.	30 Jun 2023	380	14,591 (0%)	0%	62.3	23,655	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 62.25 per share.	30 Jun 2023	390	11,890 (0%)	0%	62.3	24,278	Common Stock
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	2,505	15,493 (0%)	0%		0	Common Stock
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	11,294	11,294	-		-	Non-Qualified Stock Option (right to buy)
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	2,505	14,211 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	11,294	11,294	-		-	Non-Qualified Stock Option (right to buy)
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	2,505	13,978 (0%)	0%		0	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	11,294	11,294	-		-	Non-Qualified Stock Option (right to buy)
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	11,294	11,294	-		-	Non-Qualified Stock Option (right to buy)
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	2,505	5,904 (0%)	0%		0	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	2,505	11,500 (0%)	0%		0	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	11,294	11,294	-		-	Non-Qualified Stock Option (right to buy)
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	11,294	11,294	-		-	Non-Qualified Stock Option (right to buy)
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	2,505	7,993 (0%)	0%		0	Common Stock
Susanne Schaffert	Director	Payment of exercise price or tax liability using portion of securities received from the company at price $ 61.44 per share.	14 Jun 2023	488	3,642 (0%)	0%	61.4	29,983	Common Stock
Susanne Schaffert	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	2,505	4,130 (0%)	0%		0	Common Stock
Susanne Schaffert	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	14 Jun 2023	11,294	11,294	-		-	Non-Qualified Stock Option (right to buy)
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 72.27 per share.	31 Mar 2023	318	11,706 (0%)	0%	72.3	22,982	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 72.27 per share.	31 Mar 2023	326	8,995 (0%)	0%	72.3	23,560	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Feb 2023	3,693	0	-		-	Incentive Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.42 per share.	16 Feb 2023	3,693	56,956 (0%)	0%	65.4	241,596	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 80.08 per share.	13 Feb 2023	848	76,791 (0%)	0%	80.1	67,908	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 80.08 per share.	13 Feb 2023	331	76,460 (0%)	0%	80.1	26,506	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	31 Jan 2023	802	0	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 74.78 per share.	31 Jan 2023	802	69,326 (0%)	0%	74.8	59,974	Common Stock
Maria E. Pasquale	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 84.06 per share.	31 Jan 2023	802	68,524 (0%)	0%	84.1	67,416	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2023	4,842	0	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 84.73 per share.	30 Jan 2023	14,374	68,524 (0%)	0%	84.7	1,217,909	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 80.50 per share.	30 Jan 2023	14,374	82,898 (0%)	0%	80.5	1,157,107	Common Stock
Maria E. Pasquale	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 84.70 per share.	30 Jan 2023	11,861	68,524 (0%)	0%	84.7	1,004,627	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 72.27 per share.	30 Jan 2023	11,861	80,385 (0%)	0%	72.3	857,194	Common Stock
Maria E. Pasquale	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 84.70 per share.	30 Jan 2023	10,438	68,524 (0%)	0%	84.7	884,099	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 68.62 per share.	30 Jan 2023	10,438	78,962 (0%)	0%	68.6	716,256	Common Stock
Maria E. Pasquale	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 84.69 per share.	30 Jan 2023	12,865	68,524 (0%)	0%	84.7	1,089,537	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.36 per share.	30 Jan 2023	12,865	81,389 (0%)	0%	65.4	840,856	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2023	5,644	0	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2023	14,374	0	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2023	11,861	0	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2023	10,438	0	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2023	12,865	0	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 84.73 per share.	30 Jan 2023	4,842	68,524 (0%)	0%	84.7	410,263	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 74.78 per share.	30 Jan 2023	4,842	73,366 (0%)	0%	74.8	362,085	Common Stock
Maria E. Pasquale	EVP & General Counsel	Sale of securities on an exchange or to another person at price $ 85.07 per share.	30 Jan 2023	5,644	68,524 (0%)	0%	85.1	480,135	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 83.58 per share.	30 Jan 2023	5,644	74,168 (0%)	0%	83.6	471,726	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Jan 2023	7,000	0	-		-	Non-Qualified Stock Option (right to buy)
Vijay K. Iyengar	EVP, GMAPPS	Exercise or conversion of derivative security received from the company (such as an option) at price $ 68.62 per share.	26 Jan 2023	7,000	49,835 (0%)	0%	68.6	480,340	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 85.00 per share.	26 Jan 2023	7,000	42,835 (0%)	0%	85	595,000	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 85.00 per share.	26 Jan 2023	2,419	53,263 (0%)	0%	85	205,615	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	4,980	84,673 (0%)	0%		0	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	14,194	14,194	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	4,980	77,639 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	24,515	24,515	-		-	Employee Stock Option (right to buy)
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	29,196	435,139 (0%)	0%		0	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	86,449	86,449	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	19,354	19,354	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	4,980	77,654 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	14,194	14,194	-		-	Employee Stock Option (right to buy)
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	4,980	42,835 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	4,980	114,001 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	27,096	27,096	-		-	Employee Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	19,354	19,354	-		-	Employee Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	4,980	68,524 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	4,980	55,682 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	16,128	16,128	-		-	Employee Stock Option (right to buy)
Jonathan Elliott Dickinson	EVP, General Manager, Europe		20 Jan 2023	6,159	36,338 (0%)	0%		0	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	6,159	61,373 (0%)	0%		0	Common Stock
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	2,968	2,968	-		-	Employee Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Jan 2023	2,833	19,439 (0%)	0%		0	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		19 Jan 2023	105	30,179 (0%)	0%	83.9	8,807	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.88 per share.	19 Jan 2023	105	55,214 (0%)	0%	83.9	8,807	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		15 Jan 2023	87	30,284 (0%)	0%	81.3	7,070	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		15 Jan 2023	87	30,371 (0%)	0%	81.3	7,070	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 81.26 per share.	15 Jan 2023	87	55,319 (0%)	0%	81.3	7,070	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 81.26 per share.	15 Jan 2023	87	55,406 (0%)	0%	81.3	7,070	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 79.78 per share.	04 Jan 2023	28,399	109,021 (0%)	0%	79.8	2,265,672	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		04 Jan 2023	117	30,458 (0%)	0%	79.1	9,252	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.08 per share.	04 Jan 2023	117	55,493 (0%)	0%	79.1	9,252	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 80.32 per share.	30 Dec 2022	294	11,388 (0%)	0%	80.3	23,614	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 80.32 per share.	30 Dec 2022	252	11,473 (0%)	0%	80.3	20,241	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 80.32 per share.	30 Dec 2022	302	8,669 (0%)	0%	80.3	24,257	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 80.79 per share.	23 Dec 2022	1,654	37,855 (0%)	0%	80.8	133,627	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 80.77 per share.	23 Dec 2022	804	39,509 (0%)	0%	80.8	64,939	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 80.80 per share.	23 Dec 2022	7,000	40,313 (0%)	0%	80.8	565,600	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Exercise or conversion of derivative security received from the company (such as an option) at price $ 68.62 per share.	23 Dec 2022	7,000	47,313 (0%)	0%	68.6	480,340	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 80.80 per share.	23 Dec 2022	7,866	40,313 (0%)	0%	80.8	635,573	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Exercise or conversion of derivative security received from the company (such as an option) at price $ 72.86 per share.	23 Dec 2022	7,866	48,179 (0%)	0%	72.9	573,117	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Dec 2022	7,000	0	-		-	Non-Qualified Stock Option (right to buy)
Vijay K. Iyengar	EVP, GMAPPS	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Dec 2022	7,866	0	-		-	Non-Qualified Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 82.16 per share.	19 Dec 2022	1,223	16,606 (0%)	0%	82.2	100,482	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 82.36 per share.	12 Dec 2022	533	50,702 (0%)	0%	82.4	43,898	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 69.59 per share.	19 Oct 2022	165	8,367 (0%)	0%	69.6	11,482	Common Stock
Susanne Schaffert	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Oct 2022	1,625	1,625 (0%)	0%		0	Common Stock
Susanne Schaffert	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Oct 2022	6,751	6,751	-		-	Non-Qualified Stock Option (right to buy)
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 66.64 per share.	30 Sep 2022	339	11,094 (0%)	0%	66.6	22,591	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 66.64 per share.	30 Sep 2022	291	11,221 (0%)	0%	66.6	19,392	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 66.64 per share.	30 Sep 2022	250	8,202 (0%)	0%	66.6	16,660	Common Stock
Thomas Tray	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 83.13 per share.	22 Jul 2022	1,564	17,702 (0%)	0%	83.1	130,015	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 79.38 per share.	07 Jul 2022	2,873	72,674 (0%)	0%	79.4	228,059	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Sale of securities on an exchange or to another person at price $ 79.38 per share.	07 Jul 2022	5,787	40,313 (0%)	0%	79.4	459,372	Common Stock
Paula J. Swain	EVP, Human Resources	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	2,599	79,693 (0%)	0%	79.3	205,971	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	9,921	82,292 (0%)	0%		0	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	13,443	13,443	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	1,124	72,659 (0%)	0%	79.3	89,077	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	23,221	23,221	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	17,317	73,783 (0%)	0%		0	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	21,174	405,943 (0%)	0%	79.3	1,678,040	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	81,885	81,885	-		-	Employee Stock Option (right to buy)
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	60,433	427,117 (0%)	0%		0	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	3,506	75,547 (0%)	0%	79.3	277,851	Common Stock
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	18,332	18,332	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	13,529	79,053 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	13,443	13,443	-		-	Employee Stock Option (right to buy)
Vijay K. Iyengar	EVP, GMAPPS	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	2,599	46,100 (0%)	0%	79.3	205,971	Common Stock
Vijay K. Iyengar	EVP, GMAPPS	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	9,921	48,699 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	3,856	137,420 (0%)	0%	79.3	305,588	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	18,941	141,276 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	25,665	25,665	-		-	Employee Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	18,332	18,332	-		-	Employee Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	3,043	63,544 (0%)	0%	79.3	241,158	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	13,529	66,587 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	11,274	53,416 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	2,181	51,235 (0%)	0%	79.2	172,844	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	15,277	15,277	-		-	Employee Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	2,810	2,810	-		-	Employee Stock Option (right to buy)
Thomas Tray	Principal Accounting Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.25 per share.	02 Jul 2022	987	19,266 (0%)	0%	79.3	78,220	Common Stock
Thomas Tray	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2022	4,149	20,253 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 75.97 per share.	30 Jun 2022	321	10,755 (0%)	0%	76.0	24,386	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 75.97 per share.	30 Jun 2022	275	10,930 (0%)	0%	76.0	20,892	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 75.97 per share.	30 Jun 2022	236	7,952 (0%)	0%	76.0	17,929	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 75.63 per share.	28 Jun 2022	11,488	122,335 (0%)	0%	75.6	868,837	Common Stock
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	9,124	9,124	-		-	Non-Qualified Stock Option (right to buy)
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	2,144	12,988 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	2,144	10,434 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	9,124	9,124	-		-	Non-Qualified Stock Option (right to buy)
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	9,124	9,124	-		-	Non-Qualified Stock Option (right to buy)
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	2,144	10,655 (0%)	0%		0	Common Stock
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	9,124	9,124	-		-	Non-Qualified Stock Option (right to buy)
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	2,144	3,399 (0%)	0%		0	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	9,124	9,124	-		-	Non-Qualified Stock Option (right to buy)
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	2,144	7,716 (0%)	0%		0	Common Stock
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	2,144	5,488 (0%)	0%		0	Common Stock
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jun 2022	9,124	9,124	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 80.95 per share.	09 Apr 2022	517	53,058 (0%)	0%	80.9	41,851	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 82.96 per share.	08 Apr 2022	1,248	65,163 (0%)	0%	83.0	103,534	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 82.96 per share.	08 Apr 2022	881	66,411 (0%)	0%	83.0	73,088	Common Stock
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 68.62 per share.	08 Apr 2022	20,516	87,808 (0%)	0%	68.6	1,407,808	Common Stock
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 72.27 per share.	08 Apr 2022	21,348	88,640 (0%)	0%	72.3	1,542,820	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 84.00 per share.	08 Apr 2022	21,348	67,292 (0%)	0%	84	1,793,232	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 83.01 per share.	08 Apr 2022	20,516	67,292 (0%)	0%	83.0	1,703,033	Common Stock
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Apr 2022	21,348	0	-		-	Non-Qualified Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Apr 2022	20,516	0	-		-	Non-Qualified Stock Option (right to buy)
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 79.42 per share.	31 Mar 2022	326	8,290 (0%)	0%	79.4	25,891	Common Stock
Wendy L. Dixon	Director	Grant, award, or other acquisition of securities at price $ 79.42 per share.	31 Mar 2022	249	17,768 (0%)	0%	79.4	19,776	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 79.42 per share.	31 Mar 2022	280	8,511 (0%)	0%	79.4	22,238	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 79.42 per share.	31 Mar 2022	240	5,572 (0%)	0%	79.4	19,061	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.76 per share.	11 Feb 2022	846	56,616 (0%)	0%	66.8	56,479	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.76 per share.	11 Feb 2022	331	56,285 (0%)	0%	66.8	22,098	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		31 Jan 2022	7,375	30,214 (0%)	0%	74.2	547,151	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		24 Jan 2022	78	37,589 (0%)	0%	75.3	5,877	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 75.35 per share.	24 Jan 2022	78	55,610 (0%)	0%	75.3	5,877	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	15,054	15,054	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	15,054	15,054	-		-	Employee Stock Option (right to buy)
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	84,852	84,852	-		-	Employee Stock Option (right to buy)
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	15,054	15,054	-		-	Employee Stock Option (right to buy)
Paul Trower	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	3,250	3,250	-		-	Employee Stock Option (right to buy)
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	15,054	15,054	-		-	Employee Stock Option (right to buy)
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	15,054	15,054	-		-	Employee Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	15,054	15,054	-		-	Employee Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Jan 2022	15,054	15,054	-		-	Employee Stock Option (right to buy)
Jonathan Elliott Dickinson	EVP, General Manager, Europe		18 Jan 2022	101	30,708 (0%)	0%	75.0	7,576	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		18 Jan 2022	6,959	37,667 (0%)	0%		0	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		18 Jan 2022	101	30,809 (0%)	0%	75.0	7,576	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 75.01 per share.	18 Jan 2022	101	48,830 (0%)	0%	75.0	7,576	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	18 Jan 2022	6,959	55,688 (0%)	0%		0	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 75.01 per share.	18 Jan 2022	101	48,729 (0%)	0%	75.0	7,576	Common Stock
Paula J. Swain	EVP, Human Resources	Sale of securities on an exchange or to another person at price $ 73.31 per share.	07 Jan 2022	10,870	72,371 (0%)	0%	73.3	796,880	Common Stock
Paula J. Swain	EVP, Human Resources	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Jan 2022	10,870	0	-		-	Non Qualfied Stock Option (right to buy)
Paula J. Swain	EVP, Human Resources	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.21 per share.	07 Jan 2022	10,870	83,241 (0%)	0%	73.2	795,793	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		04 Jan 2022	136	30,910 (0%)	0%	71.8	9,766	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 71.81 per share.	04 Jan 2022	136	48,931 (0%)	0%	71.8	9,766	Common Stock
Paul Trower	Principal Accounting Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.21 per share.	03 Jan 2022	6,818	39,086 (0%)	0%	73.2	499,146	Common Stock
Paul Trower	Principal Accounting Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Jan 2022	1,396	0	-		-	Incentive Stock Option (right to buy)
Paul Trower	Principal Accounting Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Jan 2022	6,818	0	-		-	Non- Qualified Stock Option (right to buy)
Paul Trower	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 73.31 per share.	03 Jan 2022	1,396	32,268 (0%)	0%	73.3	102,341	Common Stock
Paul Trower	Principal Accounting Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.21 per share.	03 Jan 2022	1,396	33,664 (0%)	0%	73.2	102,201	Common Stock
Paul Trower	Principal Accounting Officer	Sale of securities on an exchange or to another person at price $ 73.31 per share.	03 Jan 2022	6,818	32,268 (0%)	0%	73.3	499,828	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	8,678	72,371 (0%)	0%		0	Common Stock
Paula J. Swain	EVP, Human Resources	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.21 per share.	01 Jan 2022	9,319	81,690 (0%)	0%	73.2	682,244	Common Stock
Paula J. Swain	EVP, Human Resources	Sale of securities on an exchange or to another person at price $ 73.46 per share.	01 Jan 2022	9,319	72,371 (0%)	0%	73.5	684,574	Common Stock
Paula J. Swain	EVP, Human Resources	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Jan 2022	9,319	10,870	-		-	Non Qualfied Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	14,463	57,462 (0%)	0%		0	Common Stock
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	8,678	67,292 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	8,678	38,417 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	28,926	133,823 (0%)	0%		0	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	14,463	53,575 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	8,678	42,142 (0%)	0%		0	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		01 Jan 2022	3,615	31,046 (0%)	0%		0	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	01 Jan 2022	3,615	49,067 (0%)	0%		0	Common Stock
Wendy L. Dixon	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Dec 2021	20,000	0	-		-	Non Qualfied Stock Option (right to buy)
Wendy L. Dixon	Director	Sale of securities on an exchange or to another person at price $ 22.05 per share.	23 Dec 2021	20,000	17,259 (0%)	0%	22.1	441,000	Common Stock
Wendy L. Dixon	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.25 per share.	23 Dec 2021	20,000	37,259 (0%)	0%	73.3	1,465,000	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 65.40 per share.	10 Dec 2021	533	33,464 (0%)	0%	65.4	34,858	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	379	61,338 (0%)	0%		0	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,355	63,693 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	379	40,644 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,355	42,999 (0%)	0%		0	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	13,279	345,383 (0%)	0%		0	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,227	332,104 (0%)	0%		0	Common Stock
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,355	58,614 (0%)	0%		0	Common Stock
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	379	56,259 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,355	29,739 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	379	27,384 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	379	102,542 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,355	104,897 (0%)	0%		0	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,355	39,112 (0%)	0%		0	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	379	36,757 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	379	31,642 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	19 Nov 2021	2,355	33,997 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 68.67 per share.	01 Oct 2021	389	31,263 (0%)	0%	68.7	26,713	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 68.78 per share.	30 Sep 2021	321	7,621 (0%)	0%	68.8	22,078	Common Stock
Wendy L. Dixon	Director	Grant, award, or other acquisition of securities at price $ 68.78 per share.	30 Sep 2021	244	17,259 (0%)	0%	68.8	16,782	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 68.78 per share.	30 Sep 2021	271	7,942 (0%)	0%	68.8	18,639	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 68.78 per share.	30 Sep 2021	237	5,079 (0%)	0%	68.8	16,301	Common Stock
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Sep 2021	1,255	1,255 (0%)	0%		0	Common Stock
Otis W. Brawley	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Sep 2021	5,910	5,910	-		-	Non-Qualified Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Sep 2021	382	1,912	-		-	Incentive Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.36 per share.	24 Sep 2021	382	36,187 (0%)	0%	65.4	24,968	Common Stock
Paula J. Swain	EVP, Human Resources	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.21 per share.	20 Sep 2021	1,356	60,959 (0%)	0%	73.2	99,273	Common Stock
Paula J. Swain	EVP, Human Resources	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	20 Sep 2021	1,356	0	-		-	Incentive Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 76.71 per share.	01 Sep 2021	388	31,652 (0%)	0%	76.7	29,763	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 77.49 per share.	02 Aug 2021	389	32,040 (0%)	0%	77.5	30,144	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Sale of securities on an exchange or to another person at price $ 78.29 per share.	29 Jul 2021	4,911	27,005 (0%)	0%	78.3	384,482	Common Stock
Paula J. Swain	EVP, Human Resources	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.34 per share.	02 Jul 2021	273	59,603 (0%)	0%	83.3	22,752	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	61,866 (0%)	0%		0	Common Stock
Paula J. Swain	EVP, Human Resources	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	1,990	59,876 (0%)	0%	83.6	166,324	Common Stock
Paula J. Swain	EVP, Human Resources	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	40,781 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share.	02 Jul 2021	516	40,265 (0%)	0%		0	Common Stock
Christiana Stamoulis	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Herve Hoppenot	Director, Chairman / CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	16,089	331,439 (0%)	0%	83.6	1,344,719	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	84,851	84,851	-		-	Employee Stock Option (right to buy)
Herve Hoppenot	Director, Chairman / CEO, President	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.34 per share.	02 Jul 2021	1,562	329,877 (0%)	0%	83.3	130,177	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	44,264	347,528 (0%)	0%		0	Common Stock
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	58,143 (0%)	0%		0	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.34 per share.	02 Jul 2021	273	55,880 (0%)	0%	83.3	22,752	Common Stock
Barry P. Flannelly	EVP & General Manager US	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	1,990	56,153 (0%)	0%	83.6	166,324	Common Stock
Barry P. Flannelly	EVP & General Manager US	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Wenqing Yao	EVP, Head of Discovery Chem	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.34 per share.	02 Jul 2021	405	98,575 (0%)	0%	83.3	33,753	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Wenqing Yao	EVP, Head of Discovery Chem	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	101,933 (0%)	0%		0	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	2,953	98,980 (0%)	0%	83.6	246,812	Common Stock
Paul Trower	Principal Accounting Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.34 per share.	02 Jul 2021	104	32,268 (0%)	0%	83.3	8,667	Common Stock
Paul Trower	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	3,250	3,250	-		-	Employee Stock Option (right to buy)
Paul Trower	Principal Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	4,521	33,244 (0%)	0%		0	Common Stock
Paul Trower	Principal Accounting Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	872	32,372 (0%)	0%	83.6	72,882	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	1,990	32,317 (0%)	0%	83.6	166,324	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	34,307 (0%)	0%		0	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.34 per share.	02 Jul 2021	401	31,916 (0%)	0%	83.3	33,419	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	105,518 (0%)	0%		0	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	2,953	102,565 (0%)	0%	83.6	246,812	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.34 per share.	02 Jul 2021	402	102,163 (0%)	0%	83.3	33,503	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	38,046 (0%)	0%		0	Common Stock
Maria E. Pasquale	EVP & General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	2,241	35,805 (0%)	0%	83.6	187,303	Common Stock
Maria E. Pasquale	EVP & General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	7,853	34,002 (0%)	0%		0	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.58 per share.	02 Jul 2021	1,573	32,429 (0%)	0%	83.6	131,471	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Jul 2021	15,054	15,054	-		-	Employee Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 84.09 per share.	01 Jul 2021	396	26,149 (0%)	0%	84.1	33,300	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 84.13 per share.	30 Jun 2021	283	7,300 (0%)	0%	84.1	23,809	Common Stock
Wendy L. Dixon	Director	Grant, award, or other acquisition of securities at price $ 84.13 per share.	30 Jun 2021	214	17,015 (0%)	0%	84.1	18,004	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 84.13 per share.	30 Jun 2021	238	7,671 (0%)	0%	84.1	20,023	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 84.13 per share.	30 Jun 2021	208	4,842 (0%)	0%	84.1	17,499	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Sale of securities on an exchange or to another person at price $ 85.37 per share.	28 Jun 2021	27,194	94,080 (0%)	0%	85.4	2,321,552	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Payment of exercise price or tax liability using portion of securities received from the company at price $ 85.61 per share.	28 Jun 2021	22,806	121,274 (0%)	0%	85.6	1,952,422	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 85.61 per share.	28 Jun 2021	22,079	97,665 (0%)	0%	85.6	1,890,183	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	18 Jun 2021	255	2,294	-		-	Incentive Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.36 per share.	18 Jun 2021	255	30,193 (0%)	0%	65.4	16,667	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 84.13 per share.	01 Jun 2021	395	26,545 (0%)	0%	84.1	33,231	Common Stock
Wendy L. Dixon	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	1,923	16,801 (0%)	0%		0	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	8,010	8,010	-		-	Non-Qualified Stock Option (right to buy)
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	1,923	7,433 (0%)	0%		0	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	1,923	4,634 (0%)	0%		0	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	8,010	8,010	-		-	Non-Qualified Stock Option (right to buy)
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	1,923	3,344 (0%)	0%		0	Common Stock
Katherine A. High	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	8,010	8,010	-		-	Non-Qualified Stock Option (right to buy)
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	8,010	8,010	-		-	Non-Qualified Stock Option (right to buy)
Jean-Jacques Bienaime	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	1,923	10,844 (0%)	0%		0	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	8,010	8,010	-		-	Non-Qualified Stock Option (right to buy)
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	1,923	7,017 (0%)	0%		0	Common Stock
Wendy L. Dixon	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 May 2021	8,010	8,010	-		-	Non-Qualified Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 85.40 per share.	03 May 2021	396	26,940 (0%)	0%	85.4	33,818	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Apr 2021	127	2,549	-		-	Incentive Stock Option (right to buy)
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.36 per share.	23 Apr 2021	127	29,938 (0%)	0%	65.4	8,301	Common Stock
Maria E. Pasquale	EVP & General Counsel	Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.96 per share.	09 Apr 2021	517	29,811 (0%)	0%	80.0	41,339	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 81.57 per share.	01 Apr 2021	396	27,336 (0%)	0%	81.6	32,302	Common Stock
Paul J. Clancy	Director	Grant, award, or other acquisition of securities at price $ 81.27 per share.	31 Mar 2021	298	5,094 (0%)	0%	81.3	24,218	Common Stock
Wendy L. Dixon	Director	Grant, award, or other acquisition of securities at price $ 81.27 per share.	31 Mar 2021	225	14,878 (0%)	0%	81.3	18,286	Common Stock
Jacqualyn A. Fouse	Director	Grant, award, or other acquisition of securities at price $ 81.27 per share.	31 Mar 2021	251	5,510 (0%)	0%	81.3	20,399	Common Stock
Edmund P. Harrigan	Director	Grant, award, or other acquisition of securities at price $ 81.27 per share.	31 Mar 2021	219	2,711 (0%)	0%	81.3	17,798	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Sale of securities on an exchange or to another person at price $ 81.08 per share.	29 Mar 2021	20,000	45,452 (0%)	0%	81.1	1,621,600	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.36 per share.	12 Mar 2021	128	30,328 (0%)	0%	65.4	8,366	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	12 Mar 2021	128	2,676	-		-	Incentive Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 79.73 per share.	01 Mar 2021	395	27,732 (0%)	0%	79.7	31,493	Common Stock
Herve Hoppenot	Director, Chairman / CEO, President	Purchase of securities on an exchange or from another person at price $ 77.37 per share.	23 Feb 2021	12,925	284,231 (0%)	0%	77.4	1,000,007	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.36 per share.	16 Feb 2021	127	30,200 (0%)	0%	65.4	8,301	Common Stock
Maria E. Pasquale	EVP & General Counsel	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Feb 2021	127	2,804	-		-	Incentive Stock Option (right to buy)
Christiana Stamoulis	EVP & Chief Financial Officer	Payment of exercise price or tax liability using portion of securities received from the company at price $ 84.99 per share.	11 Feb 2021	1,210	32,611 (0%)	0%	85.0	102,838	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 90.00 per share.	01 Feb 2021	395	28,127 (0%)	0%	90	35,550	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Feb 2021	961	30,759	-		-	Non-Qualified Stock Option (right to buy)
Dashyant Dhanak	EVP & Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 90.00 per share.	01 Feb 2021	961	28,522 (0%)	0%	90	86,490	Common Stock
Dashyant Dhanak	EVP & Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.42 per share.	01 Feb 2021	961	29,483 (0%)	0%	65.4	62,869	Common Stock
Barry P. Flannelly	EVP & General Manager US	Sale of securities on an exchange or to another person at price $ 100.00 per share.	25 Jan 2021	2,744	49,994 (0%)	0%	100	274,400	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Jan 2021	1,559	0	-		-	Incentive Stock Option (right to buy)
Wenqing Yao	EVP, Head of Discovery Chem	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Jan 2021	19,986	0	-		-	Non-Qualified Stock Option (right to buy)
Wenqing Yao	EVP, Head of Discovery Chem	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.21 per share.	25 Jan 2021	19,986	163,770 (0%)	0%	73.2	1,463,175	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Sale of securities on an exchange or to another person at price $ 100.00 per share.	25 Jan 2021	1,559	143,784 (0%)	0%	100	155,900	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Exercise or conversion of derivative security received from the company (such as an option) at price $ 73.21 per share.	25 Jan 2021	1,559	145,343 (0%)	0%	73.2	114,134	Common Stock
Wenqing Yao	EVP, Head of Discovery Chem	Sale of securities on an exchange or to another person at price $ 100.00 per share.	25 Jan 2021	19,986	143,784 (0%)	0%	100	1,998,600	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Jan 2021	4,116	0	-		-	Incentive Stock Option (right to buy)
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Sale of securities on an exchange or to another person at price $ 99.00 per share.	25 Jan 2021	4,116	27,158 (0%)	0%	99	407,484	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Exercise or conversion of derivative security received from the company (such as an option) at price $ 72.86 per share.	25 Jan 2021	4,116	31,274 (0%)	0%	72.9	299,892	Common Stock
Vijay K. Iyengar	EVP GPS, BD, & Licensing	Sale of securities on an exchange or to another person at price $ 99.00 per share.	25 Jan 2021	1,000	26,158 (0%)	0%	99	99,000	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 100.00 per share.	25 Jan 2021	3,795	119,744 (0%)	0%	100	379,500	Common Stock
Steven H. Stein	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Jan 2021	3,795	8,539	-		-	Non-Qualified Stock Option (right to buy)
Steven H. Stein	EVP & Chief Medical Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 68.62 per share.	25 Jan 2021	3,795	123,539 (0%)	0%	68.6	260,413	Common Stock
Jonathan Elliott Dickinson	EVP, General Manager, Europe		25 Jan 2021	78	27,135 (0%)	0%	100.5	7,839	Common Stock
Michael James Morrissey	EVP, Head of Tech. Operations	Payment of exercise price or tax liability using portion of securities received from the company at price $ 100.50 per share.	25 Jan 2021	78	65,452 (0%)	0%	100.5	7,839	Common Stock

*All Values are in $ Million

Client Category: Promoter/ KMP/ Director / Immediate Relatives / Employee / etc
Security Type: Share/ Warrants / Convertible Debentures

Data as reported to USA Exchanges

View All The Insider Trades disclosures

26.13% Fall from 52W High

High volume+loss today

Insider Trading disclosures for Incyte Corp.

The latest disclosure was made by Sheila A Denton in Incyte Corp. where a trade of 599 Common Stock done at an average price of $58.1 was reported to US exchanges on March 4, 2025.

Screeners based on Insider Trading and SAST parameters