149.1K XNAS Volume
XNAS 04 Apr, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Elizabeth H.Z. Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2025 | 694 | 6,502 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2025 | 828 | 90,884 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2025 | 1,284 | 52,951 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2025 | 828 | 11,884 (0%) | 0% | 0 | Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2025 | 1,471 | 20,751 (0%) | 0% | 0 | Common Stock | |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Sale of securities on an exchange or to another person at price $ 1.23 per share. | 14 Mar 2025 | 4,512 | 73,529 (0%) | 0% | 1.2 | 5,550 | Common Stock |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 1.23 per share. | 14 Mar 2025 | 7,329 | 180,324 (0%) | 0% | 1.2 | 9,015 | Common Stock |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Sale of securities on an exchange or to another person at price $ 1.23 per share. | 14 Mar 2025 | 1,701 | 28,881 (0%) | 0% | 1.2 | 2,092 | Common Stock |
| Mary Beth Harler | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.23 per share. | 14 Mar 2025 | 7,329 | 339,703 (1%) | 0% | 1.2 | 9,015 | Common Stock |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Sale of securities on an exchange or to another person at price $ 1.70 per share. | 15 Jan 2025 | 1,122 | 30,582 (0%) | 0% | 1.7 | 1,907 | Common Stock |
| Elizabeth H.Z. Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 1,452 | 5,808 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 1,734 | 90,056 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 2,687 | 51,667 (0%) | 0% | 0 | Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 3,078 | 19,280 (0%) | 0% | 0 | Common Stock | |
| Lee Michael | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 1,734 | 11,056 (0%) | 0% | 0 | Common Stock | |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Sale of securities on an exchange or to another person at price $ 7.48 per share. | 16 Dec 2024 | 539 | 31,704 (0%) | 0% | 7.5 | 4,032 | Common Stock |
| Mary Beth Harler | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 7.48 per share. | 16 Dec 2024 | 1,708 | 347,032 (1%) | 0% | 7.5 | 12,776 | Common Stock |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 7.48 per share. | 16 Dec 2024 | 1,708 | 187,653 (0%) | 0% | 7.5 | 12,776 | Common Stock |
| Lynn Lisa Decker | CHIEF BUSINESS OFFICER | Sale of securities on an exchange or to another person at price $ 7.48 per share. | 16 Dec 2024 | 1,063 | 78,041 (0%) | 0% | 7.5 | 7,951 | Common Stock |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2024 | 66,667 | 189,361 (0%) | 0% | 0 | Common Stock | |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2024 | 6,700 | 32,243 (0%) | 0% | 0 | Common Stock | |
| Mary Beth Harler | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2024 | 185,000 | 348,740 (1%) | 0% | 0 | Common Stock | |
| Mary Beth Harler | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Oct 2024 | 370,000 | 370,000 | - | - | Stock Option (right to buy) | |
| Elizabeth H.Z. Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 1,452 | 4,356 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 1,734 | 88,322 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 2,687 | 48,980 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 1,734 | 9,322 (0%) | 0% | 0 | Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 3,078 | 16,202 (0%) | 0% | 0 | Common Stock | |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Sale of securities on an exchange or to another person at price $ 11.54 per share. | 13 Sep 2024 | 3,946 | 250,124 (0%) | 0% | 11.5 | 45,532 | Common Stock |
| Mary Beth Harler | Head, Research & Autoimmunity | Sale of securities on an exchange or to another person at price $ 11.54 per share. | 13 Sep 2024 | 1,487 | 163,740 (0%) | 0% | 11.5 | 17,158 | Common Stock |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Sale of securities on an exchange or to another person at price $ 11.54 per share. | 13 Sep 2024 | 469 | 25,543 (0%) | 0% | 11.5 | 5,412 | Common Stock |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 11.54 per share. | 13 Sep 2024 | 1,487 | 122,694 (0%) | 0% | 11.5 | 17,158 | Common Stock |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Sale of securities on an exchange or to another person at price $ 11.54 per share. | 13 Sep 2024 | 1,487 | 242,948 (0%) | 0% | 11.5 | 17,158 | Common Stock |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Sale of securities on an exchange or to another person at price $ 11.54 per share. | 13 Sep 2024 | 925 | 79,104 (0%) | 0% | 11.5 | 10,673 | Common Stock |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Sale of securities on an exchange or to another person at price $ 11.54 per share. | 13 Sep 2024 | 1,487 | 154,331 (0%) | 0% | 11.5 | 17,158 | Common Stock |
| William Strohl | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2024 | 125,000 | 125,000 (0%) | 0% | 0 | Common Stock | |
| Julie Hambleton | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 25 Jul 2024 | 15,132 | 17,132 (0%) | 0% | 1.4 | 21,033 | Common Stock |
| Julie Hambleton | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jul 2024 | 15,132 | 0 | - | - | Stock Option (right to buy) | |
| Julie Hambleton | Director | Sale of securities on an exchange or to another person at price $ 14.00 per share. | 25 Jul 2024 | 15,132 | 2,000 (0%) | 0% | 14 | 211,848 | Common Stock |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 2,778 | 244,435 (0%) | 0% | - | Common Stock | |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Sale or transfer of securities back to the company at price $ 0.00 per share. | 19 Jul 2024 | 150,000 | 0 | - | - | Stock Option (right to buy) | |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 43,750 | 139,568 (0%) | 0% | - | Common Stock | |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 16,250 | 155,818 (0%) | 0% | - | Common Stock | |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 16,666 | 76,695 (0%) | 0% | - | Common Stock | |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Sale or transfer of securities back to the company at price $ 0.00 per share. | 19 Jul 2024 | 60,000 | 0 | - | - | Stock Option (right to buy) | |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 3,334 | 80,029 (0%) | 0% | - | Common Stock | |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Sale or transfer of securities back to the company at price $ 0.00 per share. | 19 Jul 2024 | 75,000 | 0 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 43,888 | 241,657 (0%) | 0% | - | Common Stock | |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Sale or transfer of securities back to the company at price $ 0.00 per share. | 19 Jul 2024 | 50,000 | 0 | - | - | Stock Option (right to buy) | |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale or transfer of securities back to the company at price $ 0.00 per share. | 19 Jul 2024 | 40,000 | 0 | - | - | Stock Option (right to buy) | |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 33,111 | 121,959 (0%) | 0% | - | Common Stock | |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 2,222 | 124,181 (0%) | 0% | - | Common Stock | |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale or transfer of securities back to the company at price $ 0.00 per share. | 19 Jul 2024 | 55,000 | 0 | - | - | Stock Option (right to buy) | |
| Mary Beth Harler | Head, Research & Autoimmunity | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 25,001 | 165,227 (0%) | 0% | - | Common Stock | |
| Mary Beth Harler | Head, Research & Autoimmunity | Sale or transfer of securities back to the company at price $ 0.00 per share. | 19 Jul 2024 | 200,000 | 0 | - | - | Stock Option (right to buy) | |
| Mary Beth Harler | Head, Research & Autoimmunity | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jul 2024 | 54,999 | 140,226 (0%) | 0% | - | Common Stock | |
| Elizabeth H.Z. Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2024 | 1,452 | 2,904 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2024 | 1,734 | 86,588 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2024 | 2,687 | 46,293 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2024 | 1,734 | 7,588 (0%) | 0% | 0 | Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2024 | 3,078 | 13,124 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 7.58 per share. | 14 Jun 2024 | 1,570 | 88,848 (0%) | 0% | 7.6 | 11,893 | Common Stock |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Sale of securities on an exchange or to another person at price $ 7.58 per share. | 14 Jun 2024 | 495 | 26,012 (0%) | 0% | 7.6 | 3,750 | Common Stock |
| Mary Beth Harler | Head, Research & Autoimmunity | Sale of securities on an exchange or to another person at price $ 7.58 per share. | 14 Jun 2024 | 1,570 | 85,227 (0%) | 0% | 7.6 | 11,893 | Common Stock |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 5.02 per share. | 14 Jun 2024 | 3,000 | 198,875 (0%) | 0% | 5.0 | 15,060 | Common Stock |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 5.02 per share. | 14 Jun 2024 | 3,000 | 97,388 (0%) | 0% | 5.0 | 15,060 | Common Stock |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Sale of securities on an exchange or to another person at price $ 7.58 per share. | 14 Jun 2024 | 1,570 | 95,818 (0%) | 0% | 7.6 | 11,893 | Common Stock |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Sale of securities on an exchange or to another person at price $ 7.58 per share. | 14 Jun 2024 | 977 | 60,029 (0%) | 0% | 7.6 | 7,401 | Common Stock |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Sale of securities on an exchange or to another person at price $ 7.58 per share. | 14 Jun 2024 | 4,164 | 254,070 (0%) | 0% | 7.6 | 31,544 | Common Stock |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Grant, award, or other acquisition of securities at price $ 5.02 per share. | 14 Jun 2024 | 3,000 | 258,234 (0%) | 0% | 5.0 | 15,060 | Common Stock |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Sale of securities on an exchange or to another person at price $ 7.58 per share. | 14 Jun 2024 | 1,106 | 197,769 (0%) | 0% | 7.6 | 8,378 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2024 | 3,078 | 10,046 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2024 | 1,734 | 5,854 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2024 | 2,687 | 43,606 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2024 | 1,734 | 84,854 (0%) | 0% | 0 | Common Stock | |
| Elizabeth H.Z. Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2024 | 1,452 | 1,452 (0%) | 0% | 0 | Common Stock | |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2024 | 38,583 | 255,234 (0%) | 0% | 0 | Common Stock | |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2024 | 24,019 | 195,875 (0%) | 0% | 0 | Common Stock | |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Sale of securities on an exchange or to another person at price $ 10.17 per share. | 13 Mar 2024 | 2,535 | 94,388 (0%) | 0% | 10.2 | 25,782 | Common Stock |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Sale of securities on an exchange or to another person at price $ 9.88 per share. | 13 Mar 2024 | 2,889 | 96,923 (0%) | 0% | 9.9 | 28,529 | Common Stock |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Sale of securities on an exchange or to another person at price $ 9.88 per share. | 13 Mar 2024 | 1,798 | 62,584 (0%) | 0% | 9.9 | 17,756 | Common Stock |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Sale of securities on an exchange or to another person at price $ 10.17 per share. | 13 Mar 2024 | 1,578 | 61,006 (0%) | 0% | 10.2 | 16,049 | Common Stock |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Sale of securities on an exchange or to another person at price $ 9.88 per share. | 13 Mar 2024 | 4,765 | 220,833 (0%) | 0% | 9.9 | 47,055 | Common Stock |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Sale of securities on an exchange or to another person at price $ 10.17 per share. | 13 Mar 2024 | 4,182 | 216,651 (0%) | 0% | 10.2 | 42,533 | Common Stock |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Sale of securities on an exchange or to another person at price $ 10.17 per share. | 13 Mar 2024 | 1,844 | 171,856 (0%) | 0% | 10.2 | 18,754 | Common Stock |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Sale of securities on an exchange or to another person at price $ 9.88 per share. | 13 Mar 2024 | 2,101 | 173,700 (0%) | 0% | 9.9 | 20,748 | Common Stock |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 10.17 per share. | 13 Mar 2024 | 2,543 | 90,418 (0%) | 0% | 10.2 | 25,864 | Common Stock |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 9.88 per share. | 13 Mar 2024 | 2,897 | 92,961 (0%) | 0% | 9.9 | 28,608 | Common Stock |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Sale of securities on an exchange or to another person at price $ 10.17 per share. | 13 Mar 2024 | 464 | 26,507 (0%) | 0% | 10.2 | 4,719 | Common Stock |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Sale of securities on an exchange or to another person at price $ 9.88 per share. | 13 Mar 2024 | 529 | 26,971 (0%) | 0% | 9.9 | 5,224 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 29,400 | 29,400 | - | - | Stock Option (right to buy) | |
| Julie Hambleton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 29,400 | 29,400 | - | - | Stock Option (right to buy) | |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 92,500 | 92,500 | - | - | Stock Option (right to buy) | |
| Chris H. Takimoto | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 46,250 | 99,812 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 29,400 | 29,400 | - | - | Stock Option (Right to Buy) | |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 28,750 | 64,382 (0%) | 0% | 0 | Common Stock | |
| Lisa Lynn Decker | CHIEF BUSINESS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 57,500 | 57,500 | - | - | Stock Option (right to buy) | |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 122,750 | 225,598 (0%) | 0% | 0 | Common Stock | |
| Fred Schwarzer | Director, CEO AND PRESIDENT | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 245,500 | 245,500 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 92,500 | 92,500 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 46,250 | 175,801 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 92,500 | 92,500 | - | - | Stock Option (right to buy) | |
| Misbah Tahir | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 46,250 | 95,858 (0%) | 0% | 0 | Common Stock | |
| William Strohl | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 29,400 | 29,400 | - | - | Stock Option (right to buy) | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 29,400 | 29,400 | - | - | Stock Option (right to buy) | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 29,400 | 29,400 | - | - | Stock Option (right to buy) | |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 18,750 | 27,500 (0%) | 0% | 0 | Common Stock | |
| Steven Weber | PRINCIPAL ACCOUNTING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 37,500 | 37,500 | - | - | Stock Option (right to buy) | |
| Elizabeth H.Z. Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2024 | 29,400 | 29,400 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 01 Mar 2024 | 3,026 | 4,039 (0%) | 0% | 0.9 | 2,814 | Common Stock |
| Bruce Keyt | CHIEF SCIENTIFIC OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 3,026 | 0 | - | - | Stock Option (right to buy) | |
| Behrens Wilsey Kathleen M. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2023 | 800 | 6,968 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2023 | 492 | 4,120 (0%) | 0% | 0 | Common Stock | |
| Teng Christina Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2023 | 738 | 40,919 (0%) | 0% | 0 | Common Stock | |
| Haldor Topsoe Jakob | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Dec 2023 | 492 | 83,120 (0%) | 0% | 0 | Common Stock | |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 5.78 per share. | 13 Dec 2023 | 17,576 | 102,848 (0%) | 0% | 5.8 | 101,558 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 5.78 per share. | 13 Dec 2023 | 7,574 | 129,551 (0%) | 0% | 5.8 | 43,764 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 5.78 per share. | 13 Dec 2023 | 4,369 | 35,632 (0%) | 0% | 5.8 | 25,245 | Common Stock |
| Lynn Lisa Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 6.21 per share. | 29 Nov 2023 | 1,180 | 40,001 (0%) | 0% | 6.2 | 7,331 | 11/29/2023 |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 9.42 per share. | 03 Jul 2023 | 936 | 40,017 (0%) | 0% | 9.4 | 8,818 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 800 | 5,368 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 1,138 | 1,138 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 492 | 3,136 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 9.32 per share. | 30 Jun 2023 | 3,000 | 9,800 (0%) | 0% | 9.3 | 27,957 | Common Stock |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 738 | 39,443 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 9.25 per share. | 29 Jun 2023 | 3,500 | 81,644 (0%) | 0% | 9.3 | 32,375 | Common Stock |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jun 2023 | 492 | 82,136 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 9.10 per share. | 29 Jun 2023 | 3,500 | 78,144 (0%) | 0% | 9.1 | 31,847 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 26 Jun 2023 | 112,500 | 330,700 (1%) | 0% | 8 | 900,000 | Common Stock |
| Christina Teng Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 Jun 2023 | 1,687,500 | 5,044,295 | - | - | Non-Voting Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 Jun 2023 | 1,687,500 | 5,044,295 | - | - | Non-Voting Common Stock | |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 23 May 2023 | 15 | 54,742 (0%) | 0% | 13 | 195 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 12.30 per share. | 23 May 2023 | 1,244 | 54,757 (0%) | 0% | 12.3 | 15,302 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 11.71 per share. | 23 May 2023 | 962 | 56,001 (0%) | 0% | 11.7 | 11,265 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 11.71 per share. | 23 May 2023 | 961 | 42,440 (0%) | 0% | 11.7 | 11,253 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 23 May 2023 | 15 | 41,181 (0%) | 0% | 13 | 195 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 12.30 per share. | 23 May 2023 | 1,244 | 41,196 (0%) | 0% | 12.3 | 15,302 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 12.30 per share. | 23 May 2023 | 1,244 | 121,776 (0%) | 0% | 12.3 | 15,302 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 11.71 per share. | 23 May 2023 | 960 | 123,020 (0%) | 0% | 11.7 | 11,242 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 23 May 2023 | 15 | 121,761 (0%) | 0% | 13 | 195 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 11.71 per share. | 23 May 2023 | 960 | 139,040 (0%) | 0% | 11.7 | 11,242 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 23 May 2023 | 12 | 138,058 (0%) | 0% | 13 | 156 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 12.30 per share. | 23 May 2023 | 970 | 138,070 (0%) | 0% | 12.3 | 11,931 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 12.30 per share. | 23 May 2023 | 1,244 | 50,726 (0%) | 0% | 12.3 | 15,302 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 23 May 2023 | 15 | 50,711 (0%) | 0% | 13 | 195 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 11.71 per share. | 23 May 2023 | 398 | 51,970 (0%) | 0% | 11.7 | 4,661 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 13.00 per share. | 23 May 2023 | 15 | 40,953 (0%) | 0% | 13 | 195 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 12.30 per share. | 23 May 2023 | 1,244 | 40,968 (0%) | 0% | 12.3 | 15,302 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Apr 2023 | 8,497 | 41,479 (0%) | 0% | 0 | Common Stock | |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Apr 2023 | 34,200 | 122,060 (0%) | 0% | 0 | Common Stock | |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Apr 2023 | 21,126 | 138,080 (0%) | 0% | 0 | Common Stock | |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Apr 2023 | 8,334 | 42,212 (0%) | 0% | 0 | Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 15,500 | 15,500 | - | - | Stock Option (right to buy) | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 15,500 | 15,500 | - | - | Stock Option (right to buy) | |
| Julie Hambleton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 15,500 | 15,500 | - | - | Stock Option (right to buy) | |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 26,250 | 55,039 (0%) | 0% | 0 | Common Stock | |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 52,500 | 52,500 | - | - | Stock Option (right to buy) | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 15,500 | 15,500 | - | - | Stock Option (Right to Buy) | |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 16,250 | 32,982 (0%) | 0% | 0 | Common Stock | |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 135,000 | 135,000 | - | - | Stock Option (right to buy) | |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 67,500 | 87,860 (0%) | 0% | 0 | Common Stock | |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 52,500 | 52,500 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 26,250 | 116,954 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 52,500 | 52,500 | - | - | Stock Option (right to buy) | |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 26,250 | 51,572 (0%) | 0% | 0 | Common Stock | |
| William Strohl | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 15,500 | 15,500 | - | - | Stock Option (right to buy) | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 15,500 | 15,500 | - | - | Stock Option (right to buy) | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 15,500 | 15,500 | - | - | Stock Option (right to buy) | |
| Steven Weber | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 8,750 | 8,750 (0%) | 0% | 0 | Common Stock | |
| Steven Weber | Principal Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 17,500 | 17,500 | - | - | Stock Option (right to buy) | |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 16,250 | 34,813 (0%) | 0% | 0 | Common Stock | |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2023 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 12.60 per share. | 04 Apr 2023 | 935 | 33,878 (0%) | 0% | 12.6 | 11,781 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 800 | 4,568 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 1,138 | 1,138 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Mar 2023 | 533 | 36,371 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Mar 2023 | 533 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 492 | 2,644 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 738 | 38,705 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 492 | 74,644 (0%) | 0% | 0 | Common Stock | |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 18.73 per share. | 14 Mar 2023 | 1,768 | 28,789 (0%) | 0% | 18.7 | 33,118 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 18.73 per share. | 14 Mar 2023 | 1,061 | 16,732 (0%) | 0% | 18.7 | 19,875 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.73 per share. | 14 Mar 2023 | 1,293 | 90,704 (0%) | 0% | 18.7 | 24,220 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 18.73 per share. | 14 Mar 2023 | 1,768 | 25,322 (0%) | 0% | 18.7 | 33,118 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 18.73 per share. | 14 Mar 2023 | 1,061 | 18,563 (0%) | 0% | 18.7 | 19,875 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jan 2023 | 33,756 | 0 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 05 Jan 2023 | 33,756 | 91,997 (0%) | 0% | 0.9 | 31,393 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Dec 2022 | 374 | 3,768 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Dec 2022 | 533 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Dec 2022 | 533 | 35,838 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Dec 2022 | 533 | 533 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Dec 2022 | 230 | 2,152 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Dec 2022 | 346 | 37,967 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Dec 2022 | 230 | 74,152 (0%) | 0% | 0 | Common Stock | |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 19.36 per share. | 16 Dec 2022 | 1,938 | 30,557 (0%) | 0% | 19.4 | 37,519 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 18.77 per share. | 16 Dec 2022 | 3,492 | 32,495 (0%) | 0% | 18.8 | 65,561 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 18.77 per share. | 16 Dec 2022 | 1,598 | 18,679 (0%) | 0% | 18.8 | 30,002 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 19.36 per share. | 16 Dec 2022 | 886 | 17,793 (0%) | 0% | 19.4 | 17,153 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 19.36 per share. | 16 Dec 2022 | 4,414 | 20,360 (0%) | 0% | 19.4 | 85,453 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 18.77 per share. | 16 Dec 2022 | 7,955 | 24,774 (0%) | 0% | 18.8 | 149,352 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.77 per share. | 16 Dec 2022 | 3,454 | 60,158 (0%) | 0% | 18.8 | 64,847 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.36 per share. | 16 Dec 2022 | 1,917 | 58,241 (0%) | 0% | 19.4 | 37,112 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 19.36 per share. | 16 Dec 2022 | 815 | 30,891 (0%) | 0% | 19.4 | 15,778 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 16 Dec 2022 | 3,801 | 27,090 (0%) | 0% | 20 | 76,020 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 18.77 per share. | 16 Dec 2022 | 1,468 | 31,706 (0%) | 0% | 18.8 | 27,561 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 18.77 per share. | 16 Dec 2022 | 2,800 | 21,178 (0%) | 0% | 18.8 | 52,569 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 19.36 per share. | 16 Dec 2022 | 1,554 | 19,624 (0%) | 0% | 19.4 | 30,085 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 21.99 per share. | 23 Nov 2022 | 277 | 35,987 (0%) | 0% | 22.0 | 6,092 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 21.38 per share. | 23 Nov 2022 | 600 | 36,264 (0%) | 0% | 21.4 | 12,826 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 21.99 per share. | 23 Nov 2022 | 397 | 20,277 (0%) | 0% | 22.0 | 8,731 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 21.38 per share. | 23 Nov 2022 | 861 | 20,674 (0%) | 0% | 21.4 | 18,405 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 21.99 per share. | 23 Nov 2022 | 397 | 32,729 (0%) | 0% | 22.0 | 8,731 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 21.38 per share. | 23 Nov 2022 | 861 | 33,126 (0%) | 0% | 21.4 | 18,405 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 21.99 per share. | 23 Nov 2022 | 277 | 38,612 (0%) | 0% | 22.0 | 6,092 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 21.38 per share. | 23 Nov 2022 | 600 | 38,889 (0%) | 0% | 21.4 | 12,826 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 21.99 per share. | 23 Nov 2022 | 277 | 33,174 (0%) | 0% | 22.0 | 6,092 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 21.38 per share. | 23 Nov 2022 | 600 | 33,451 (0%) | 0% | 21.4 | 12,826 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 12.84 per share. | 23 Nov 2022 | 353 | 34,051 (0%) | 0% | 12.8 | 4,533 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 21.99 per share. | 23 Nov 2022 | 397 | 23,978 (0%) | 0% | 22.0 | 8,731 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 21.38 per share. | 23 Nov 2022 | 861 | 24,375 (0%) | 0% | 21.4 | 18,405 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 17.14 per share. | 08 Nov 2022 | 60,000 | 218,200 (0%) | 0% | 17.1 | 1,028,550 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 22.84 per share. | 04 Oct 2022 | 25,000 | 39,489 (0%) | 0% | 22.8 | 570,980 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Oct 2022 | 25,000 | 58,756 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 04 Oct 2022 | 25,000 | 64,489 (0%) | 0% | 0.9 | 23,250 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2022 | 374 | 3,394 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2022 | 230 | 1,922 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2022 | 346 | 37,621 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2022 | 230 | 73,922 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Sep 2022 | 533 | 533 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Purchase of securities on an exchange or from another person at price $ 19.62 per share. | 29 Sep 2022 | 5,821 | 35,305 (0%) | 0% | 19.6 | 114,213 | Common Stock |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Sep 2022 | 533 | 22,805 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Purchase of securities on an exchange or from another person at price $ 20.97 per share. | 27 Sep 2022 | 6,172 | 29,484 (0%) | 0% | 21.0 | 129,403 | Common Stock |
| Michael D. Loberg | Director | Purchase of securities on an exchange or from another person at price $ 19.99 per share. | 27 Sep 2022 | 507 | 23,312 (0%) | 0% | 20.0 | 10,137 | Common Stock |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Sep 2022 | 533 | 0 (0%) | 0% | 0 | Common Stock | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.06 per share. | 06 Sep 2022 | 5,000 | 39,489 (0%) | 0% | 19.1 | 95,321 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Sep 2022 | 10,000 | 83,756 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Sep 2022 | 10,000 | 93,756 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Sep 2022 | 5,000 | 103,756 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.34 per share. | 06 Sep 2022 | 2,735 | 39,489 (0%) | 0% | 20.3 | 55,632 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.57 per share. | 06 Sep 2022 | 7,265 | 42,224 (0%) | 0% | 19.6 | 142,196 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 06 Sep 2022 | 10,000 | 49,489 (0%) | 0% | 0.9 | 9,300 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.04 per share. | 06 Sep 2022 | 10,000 | 39,489 (0%) | 0% | 19.0 | 190,392 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 06 Sep 2022 | 10,000 | 49,489 (0%) | 0% | 0.9 | 9,300 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 06 Sep 2022 | 5,000 | 44,489 (0%) | 0% | 0.9 | 4,650 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 18 Aug 2022 | 6,300 | 45,789 (0%) | 0% | 0.9 | 5,859 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 18 Aug 2022 | 10,000 | 49,489 (0%) | 0% | 0.9 | 9,300 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 22.54 per share. | 18 Aug 2022 | 10,000 | 39,489 (0%) | 0% | 22.5 | 225,352 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 18 Aug 2022 | 8,700 | 48,189 (0%) | 0% | 0.9 | 8,091 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 22.82 per share. | 18 Aug 2022 | 8,700 | 39,489 (0%) | 0% | 22.8 | 198,544 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.71 per share. | 18 Aug 2022 | 6,300 | 39,489 (0%) | 0% | 20.7 | 130,451 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2022 | 10,000 | 123,756 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2022 | 8,700 | 115,056 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Aug 2022 | 6,300 | 108,756 | - | - | Stock Option (right to buy) | |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 374 | 3,020 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 533 | 533 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Jun 2022 | 533 | 22,272 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Jun 2022 | 533 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 230 | 1,692 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 346 | 37,275 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 230 | 73,692 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 17.10 per share. | 26 May 2022 | 950 | 33,698 (0%) | 0% | 17.1 | 16,247 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 17.10 per share. | 24 May 2022 | 938 | 36,864 (0%) | 0% | 17.1 | 16,043 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 17.10 per share. | 24 May 2022 | 1,362 | 21,535 (0%) | 0% | 17.1 | 23,293 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 17.10 per share. | 24 May 2022 | 1,362 | 33,987 (0%) | 0% | 17.1 | 23,294 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.10 per share. | 24 May 2022 | 939 | 39,489 (0%) | 0% | 17.1 | 16,058 | Common Stock |
| George Gauthier | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 17.10 per share. | 24 May 2022 | 1,340 | 25,236 (0%) | 0% | 17.1 | 22,917 | Common Stock |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 16.00 per share. | 20 May 2022 | 1,481 | 73,462 (0%) | 0% | 16 | 23,696 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 12.38 per share. | 13 May 2022 | 825 | 37,802 (0%) | 0% | 12.4 | 10,214 | Common Stock |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 12.38 per share. | 13 May 2022 | 413 | 22,897 (0%) | 0% | 12.4 | 5,113 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 12.38 per share. | 13 May 2022 | 414 | 35,349 (0%) | 0% | 12.4 | 5,125 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 12.38 per share. | 13 May 2022 | 413 | 40,428 (0%) | 0% | 12.4 | 5,113 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 12.38 per share. | 13 May 2022 | 391 | 34,648 (0%) | 0% | 12.4 | 4,841 | Common Stock |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 12.38 per share. | 13 May 2022 | 413 | 26,576 (0%) | 0% | 12.4 | 5,113 | Common Stock |
| Christina Teng Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 14.08 per share. | 12 May 2022 | 2,290 | 2,290 (0%) | 0% | 14.1 | 32,248 | Common Stock |
| Christina Teng Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 14.99 per share. | 12 May 2022 | 4,510 | 6,800 (0%) | 0% | 15.0 | 67,593 | Common Stock |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 14.17 per share. | 12 May 2022 | 8,254 | 64,131 (0%) | 0% | 14.2 | 116,991 | Common Stock |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 14.86 per share. | 12 May 2022 | 7,850 | 71,981 (0%) | 0% | 14.9 | 116,683 | Common Stock |
| Christina Teng Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Apr 2022 | 1,086,957 | 3,356,795 | - | - | Non-Voting Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Apr 2022 | 1,086,957 | 3,356,795 | - | - | Non-Voting Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 23.00 per share. | 31 Mar 2022 | 8,696 | 29,807 (0%) | 0% | 23 | 200,008 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 374 | 2,646 (0%) | 0% | 0 | Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 23.00 per share. | 31 Mar 2022 | 43,478 | 158,200 (0%) | 0% | 23 | 999,994 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 23.00 per share. | 31 Mar 2022 | 8,695 | 29,806 (0%) | 0% | 23 | 199,985 | Common Stock |
| Michael D. Loberg | Director | Purchase of securities on an exchange or from another person at price $ 23.00 per share. | 31 Mar 2022 | 21,739 | 21,739 (0%) | 0% | 23 | 499,997 | Common Stock |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 533 | 533 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Mar 2022 | 300 | 600 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Mar 2022 | 300 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 230 | 1,462 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 346 | 36,929 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 230 | 55,877 (0%) | 0% | 0 | Common Stock | |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2022 | 14,477 | 36,977 (0%) | 0% | 0 | Common Stock | |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2022 | 4,617 | 22,484 (0%) | 0% | 0 | Common Stock | |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2022 | 23,002 | 34,935 (0%) | 0% | 0 | Common Stock | |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2022 | 14,319 | 40,015 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2022 | 6,084 | 34,257 (0%) | 0% | 0 | Common Stock | |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2022 | 8,096 | 26,163 (0%) | 0% | 0 | Common Stock | |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 29,497 | 29,497 | - | - | Stock Option (right to buy) | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 29,497 | 29,497 | - | - | Stock Option (right to buy) | |
| Julie Hambleton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 29,497 | 29,497 | - | - | Stock Option (right to buy) | |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 12,500 | 22,500 (0%) | 0% | 0 | Common Stock | |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 29,497 | 29,497 | - | - | Stock Option (Right to Buy) | |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 45,000 | - | - | Stock Option (right to buy) | |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 7,500 | 17,867 (0%) | 0% | 0 | Common Stock | |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 350,000 | 350,000 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 12,500 | 25,696 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 12,500 | 28,173 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| William Strohl | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 29,497 | 29,497 | - | - | Stock Option (right to buy) | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 29,497 | 29,497 | - | - | Stock Option (right to buy) | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 29,497 | 29,497 | - | - | Stock Option (right to buy) | |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 7,500 | 18,067 (0%) | 0% | 0 | Common Stock | |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 45,000 | - | - | Stock Option (right to buy) | |
| Lisa Lynn Decker | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 50.99 per share. | 15 Nov 2021 | 367 | 367 (0%) | 0% | 51.0 | 18,713 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 50.99 per share. | 15 Nov 2021 | 233 | 1,933 (0%) | 0% | 51.0 | 11,881 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 50.99 per share. | 15 Nov 2021 | 139 | 3,196 (0%) | 0% | 51.0 | 7,088 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 50.99 per share. | 15 Nov 2021 | 86 | 5,673 (0%) | 0% | 51.0 | 4,385 | Common Stock |
| George Gauthier | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 50.99 per share. | 15 Nov 2021 | 367 | 567 (0%) | 0% | 51.0 | 18,713 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 49.78 per share. | 01 Nov 2021 | 1,174 | 4,383 (0%) | 0% | 49.8 | 58,442 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2021 | 2,500 | 264 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 51.37 per share. | 01 Nov 2021 | 1,326 | 3,057 (0%) | 0% | 51.4 | 68,117 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 01 Nov 2021 | 2,500 | 5,557 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 65.91 per share. | 01 Oct 2021 | 1,258 | 4,299 (0%) | 0% | 65.9 | 82,915 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Oct 2021 | 2,500 | 2,764 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 64.10 per share. | 01 Oct 2021 | 1,242 | 3,057 (0%) | 0% | 64.1 | 79,617 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 01 Oct 2021 | 2,500 | 5,557 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2021 | 211 | 2,061 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2021 | 300 | 300 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Sep 2021 | 300 | 12,996 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Sep 2021 | 300 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2021 | 130 | 1,102 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2021 | 195 | 36,388 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2021 | 130 | 55,517 (0%) | 0% | 0 | Common Stock | |
| Julie Hambleton | Director | Sale of securities on an exchange or to another person at price $ 80.00 per share. | 09 Aug 2021 | 1,000 | 2,000 (0%) | 0% | 80 | 80,000 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 67.00 per share. | 02 Aug 2021 | 1,242 | 3,057 (0%) | 0% | 67 | 83,214 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Aug 2021 | 2,500 | 7,764 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.96 per share. | 02 Aug 2021 | 1,258 | 4,299 (0%) | 0% | 67.0 | 84,236 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 02 Aug 2021 | 2,500 | 5,557 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Chris H. Takimoto | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jul 2021 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 01 Jul 2021 | 1,900 | 118,418 (0%) | 0% | 1.4 | 2,641 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2021 | 1,900 | 338,340 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 82.75 per share. | 01 Jul 2021 | 943 | 116,518 (0%) | 0% | 82.7 | 78,033 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 89.43 per share. | 01 Jul 2021 | 957 | 117,461 (0%) | 0% | 89.4 | 85,585 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 89.43 per share. | 01 Jul 2021 | 1,253 | 4,304 (0%) | 0% | 89.4 | 112,056 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 01 Jul 2021 | 2,500 | 5,557 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2021 | 2,500 | 10,264 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 82.50 per share. | 01 Jul 2021 | 1,247 | 3,057 (0%) | 0% | 82.5 | 102,878 | Common Stock |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2021 | 130 | 972 (0%) | 0% | 0 | Common Stock | |
| Julie Hambleton | Director | Sale of securities on an exchange or to another person at price $ 80.00 per share. | 01 Jun 2021 | 2,000 | 3,000 (0%) | 0% | 80 | 160,000 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 01 Jun 2021 | 1,900 | 118,418 (0%) | 0% | 1.4 | 2,641 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 1,900 | 340,240 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 79.15 per share. | 01 Jun 2021 | 941 | 116,518 (0%) | 0% | 79.1 | 74,480 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.99 per share. | 01 Jun 2021 | 959 | 117,459 (0%) | 0% | 80.0 | 76,710 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 01 Jun 2021 | 2,500 | 5,557 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 2,500 | 12,764 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 79.15 per share. | 01 Jun 2021 | 1,245 | 3,057 (0%) | 0% | 79.2 | 98,542 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 79.99 per share. | 01 Jun 2021 | 1,255 | 4,302 (0%) | 0% | 80.0 | 100,387 | Common Stock |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 70.00 per share. | 26 May 2021 | 444 | 116,518 (0%) | 0% | 70 | 31,080 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 45.90 per share. | 14 May 2021 | 313 | 1,700 (0%) | 0% | 45.9 | 14,367 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2021 | 900 | 342,140 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 14 May 2021 | 900 | 117,418 (0%) | 0% | 1.4 | 1,251 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 68.76 per share. | 14 May 2021 | 456 | 116,962 (0%) | 0% | 68.8 | 31,355 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 45.90 per share. | 14 May 2021 | 288 | 3,057 (0%) | 0% | 45.9 | 13,219 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 45.91 per share. | 14 May 2021 | 45 | 5,587 (0%) | 0% | 45.9 | 2,066 | Common Stock |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 62.32 per share. | 05 May 2021 | 469 | 116,518 (0%) | 0% | 62.3 | 29,226 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 May 2021 | 950 | 343,040 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 03 May 2021 | 950 | 117,468 (0%) | 0% | 1.4 | 1,321 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 68.03 per share. | 03 May 2021 | 481 | 116,987 (0%) | 0% | 68.0 | 32,722 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 62.50 per share. | 03 May 2021 | 1,243 | 2,769 (0%) | 0% | 62.5 | 77,688 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 03 May 2021 | 2,500 | 5,269 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 68.03 per share. | 03 May 2021 | 1,257 | 4,012 (0%) | 0% | 68.0 | 85,514 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 May 2021 | 2,500 | 15,264 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.40 per share. | 05 Apr 2021 | 678 | 117,740 (0%) | 0% | 83.4 | 56,545 | Common Stock |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 82.00 per share. | 05 Apr 2021 | 1,222 | 116,518 (0%) | 0% | 82 | 100,204 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 05 Apr 2021 | 1,900 | 118,418 (0%) | 0% | 1.4 | 2,641 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Apr 2021 | 1,900 | 343,990 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Apr 2021 | 2,500 | 17,764 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 82.00 per share. | 05 Apr 2021 | 1,254 | 2,769 (0%) | 0% | 82 | 102,828 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.40 per share. | 05 Apr 2021 | 1,246 | 4,023 (0%) | 0% | 83.4 | 103,916 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 05 Apr 2021 | 2,500 | 5,269 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2021 | 211 | 94,139 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Mar 2021 | 535 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2021 | 300 | 300 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Mar 2021 | 535 | 2,140 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2021 | 130 | 842 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2021 | 195 | 35,998 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2021 | 130 | 55,257 (0%) | 0% | 0 | Common Stock | |
| Misbah Tahir | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 2,750 | 120,097 | - | - | Stock Option (right to buy) | |
| Misbah Tahir | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 05 Mar 2021 | 2,750 | 5,542 (0%) | 0% | 1.4 | 3,823 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 01 Mar 2021 | 1,900 | 118,418 (0%) | 0% | 1.4 | 2,641 | Common Stock |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 90.25 per share. | 01 Mar 2021 | 1,224 | 116,518 (0%) | 0% | 90.3 | 110,466 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 1,900 | 345,890 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 92.44 per share. | 01 Mar 2021 | 676 | 117,742 (0%) | 0% | 92.4 | 62,489 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 01 Mar 2021 | 2,500 | 5,269 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 2,500 | 20,264 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 90.25 per share. | 01 Mar 2021 | 1,619 | 2,769 (0%) | 0% | 90.3 | 146,115 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 92.44 per share. | 01 Mar 2021 | 881 | 4,388 (0%) | 0% | 92.4 | 81,440 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 6,423 | 6,423 | - | - | Stock Option (right to buy) | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 6,423 | 6,423 | - | - | Stock Option (right to buy) | |
| Julie Hambleton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 6,423 | 6,423 | - | - | Stock Option (right to buy) | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 6,423 | 6,423 | - | - | Stock Option (Right to Buy) | |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 125,000 | 125,000 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| William Strohl | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 6,423 | 6,423 | - | - | Stock Option (right to buy) | |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 6,423 | 6,423 | - | - | Stock Option (right to buy) | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2021 | 6,423 | 6,423 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 96.40 per share. | 02 Feb 2021 | 674 | 117,699 (0%) | 0% | 96.4 | 64,974 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2021 | 1,900 | 347,790 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 96.00 per share. | 02 Feb 2021 | 1,226 | 116,473 (0%) | 0% | 96 | 117,696 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 02 Feb 2021 | 1,900 | 118,373 (0%) | 0% | 1.4 | 2,641 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 96.40 per share. | 02 Feb 2021 | 881 | 4,388 (0%) | 0% | 96.4 | 84,928 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 02 Feb 2021 | 2,500 | 5,269 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2021 | 2,500 | 22,764 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 96.00 per share. | 02 Feb 2021 | 1,619 | 2,769 (0%) | 0% | 96 | 155,424 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 77.27 per share. | 04 Jan 2021 | 798 | 117,575 (0%) | 0% | 77.3 | 61,661 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2021 | 1,900 | 349,690 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 79.25 per share. | 04 Jan 2021 | 1,102 | 116,473 (0%) | 0% | 79.3 | 87,334 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 04 Jan 2021 | 1,900 | 118,373 (0%) | 0% | 1.4 | 2,641 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 04 Jan 2021 | 2,500 | 5,269 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 88.07 per share. | 04 Jan 2021 | 883 | 1,013 (0%) | 0% | 88.1 | 77,766 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2021 | 2,500 | 25,264 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 79.33 per share. | 04 Jan 2021 | 1,503 | 2,769 (0%) | 0% | 79.3 | 119,233 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 77.27 per share. | 04 Jan 2021 | 997 | 4,272 (0%) | 0% | 77.3 | 77,038 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Dec 2020 | 2,750 | 122,847 | - | - | Stock Option (right to buy) | |
| Misbah Tahir | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 21 Dec 2020 | 2,750 | 2,792 (0%) | 0% | 1.4 | 3,823 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 86.10 per share. | 16 Dec 2020 | 1,618 | 2,769 (0%) | 0% | 86.1 | 139,310 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 89.38 per share. | 16 Dec 2020 | 882 | 4,387 (0%) | 0% | 89.4 | 78,833 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2020 | 2,500 | 27,764 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 16 Dec 2020 | 2,500 | 5,269 (0%) | 0% | 0.9 | 2,325 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 90.00 per share. | 11 Dec 2020 | 11,111 | 21,111 (0%) | 0% | 90 | 999,990 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 90.00 per share. | 11 Dec 2020 | 11,111 | 21,111 (0%) | 0% | 90 | 999,990 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 90.00 per share. | 11 Dec 2020 | 22,222 | 22,222 (0%) | 0% | 90 | 1,999,980 | Common Stock |
| Christina Teng Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 90.00 per share. | 11 Dec 2020 | 111,111 | 10,400,564 (34%) | 0% | 90 | 9,999,990 | Common Stock |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 90.00 per share. | 11 Dec 2020 | 111,111 | 10,400,564 (34%) | 0% | 90 | 9,999,990 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 72.92 per share. | 07 Dec 2020 | 681 | 117,692 (0%) | 0% | 72.9 | 49,659 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Dec 2020 | 1,900 | 351,590 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 91.00 per share. | 07 Dec 2020 | 1,219 | 116,473 (0%) | 0% | 91 | 110,929 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 07 Dec 2020 | 1,900 | 118,373 (0%) | 0% | 1.4 | 2,641 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 01 Dec 2020 | 950 | 117,423 (0%) | 0% | 1.4 | 1,321 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2020 | 950 | 353,490 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 63.15 per share. | 01 Dec 2020 | 608 | 116,473 (0%) | 0% | 63.2 | 38,398 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 64.22 per share. | 01 Dec 2020 | 342 | 117,081 (0%) | 0% | 64.2 | 21,963 | Common Stock |
| Fred Schwarzer | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 45.45 per share. | 13 Nov 2020 | 291 | 198,105 (0%) | 0% | 45.5 | 13,226 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 45.45 per share. | 13 Nov 2020 | 132 | 2,769 (0%) | 0% | 45.4 | 5,999 | Common Stock |
| Misbah Tahir | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 45.45 per share. | 13 Nov 2020 | 42 | 42 (0%) | 0% | 45.5 | 1,909 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 02 Nov 2020 | 950 | 117,468 (0%) | 0% | 1.4 | 1,321 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Nov 2020 | 950 | 354,440 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 02 Nov 2020 | 605 | 116,473 (0%) | 0% | 50 | 30,250 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 52.39 per share. | 02 Nov 2020 | 345 | 117,123 (0%) | 0% | 52.4 | 18,075 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 357 | 93,571 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 535 | 535 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Oct 2020 | 535 | 1,070 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Oct 2020 | 535 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 178 | 534 (0%) | 0% | 0 | Common Stock | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 73.50 per share. | 01 Oct 2020 | 1,830 | 116,518 (0%) | 0% | 73.5 | 134,505 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 01 Oct 2020 | 2,850 | 119,368 (0%) | 0% | 1.4 | 3,962 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Oct 2020 | 2,850 | 355,390 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 76.13 per share. | 01 Oct 2020 | 1,020 | 118,348 (0%) | 0% | 76.1 | 77,653 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 73.59 per share. | 01 Oct 2020 | 1,000 | 1,896 (0%) | 0% | 73.6 | 73,590 | Common Stock |
| Christina Teng Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 357 | 35,446 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Oct 2020 | 178 | 54,949 (0%) | 0% | 0 | Common Stock | |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 17 Sep 2020 | 950 | 117,468 (0%) | 0% | 1.4 | 1,321 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Sep 2020 | 950 | 358,240 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 77.91 per share. | 17 Sep 2020 | 609 | 116,518 (0%) | 0% | 77.9 | 47,447 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 71.14 per share. | 17 Sep 2020 | 341 | 117,127 (0%) | 0% | 71.1 | 24,259 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 63.06 per share. | 10 Sep 2020 | 2,791 | 88,293 (0%) | 0% | 63.1 | 176,004 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 56.41 per share. | 10 Sep 2020 | 978 | 64,192 (0%) | 0% | 56.4 | 55,165 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 57.75 per share. | 10 Sep 2020 | 2,367 | 66,559 (0%) | 0% | 57.7 | 136,691 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 58.75 per share. | 10 Sep 2020 | 5,132 | 71,691 (0%) | 0% | 58.8 | 301,511 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 59.65 per share. | 10 Sep 2020 | 4,442 | 76,133 (0%) | 0% | 59.6 | 264,948 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 60.86 per share. | 10 Sep 2020 | 5,033 | 81,166 (0%) | 0% | 60.9 | 306,333 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 61.80 per share. | 10 Sep 2020 | 4,336 | 85,502 (0%) | 0% | 61.8 | 267,984 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 63.58 per share. | 10 Sep 2020 | 3,351 | 91,644 (0%) | 0% | 63.6 | 213,044 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Purchase of securities on an exchange or from another person at price $ 64.80 per share. | 10 Sep 2020 | 1,570 | 93,214 (0%) | 0% | 64.8 | 101,729 | Common Stock |
| Bruce Keyt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 60.00 per share. | 10 Sep 2020 | 1,000 | 2,896 (0%) | 0% | 60 | 60,000 | Common Stock |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 50.20 per share. | 08 Sep 2020 | 602 | 116,518 (0%) | 0% | 50.2 | 30,220 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2020 | 950 | 359,190 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 44.77 per share. | 01 Sep 2020 | 348 | 117,120 (0%) | 0% | 44.8 | 15,580 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 01 Sep 2020 | 950 | 117,468 (0%) | 0% | 1.4 | 1,321 | Common Stock |
| Daniel Chen | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 45.13 per share. | 27 Aug 2020 | 605 | 116,518 (0%) | 0% | 45.1 | 27,301 | Common Stock |
| Daniel Chen | Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 53.26 per share. | 11 Aug 2020 | 345 | 117,123 (0%) | 0% | 53.3 | 18,375 | Common Stock |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Aug 2020 | 950 | 360,140 | - | - | Stock Option (right to buy) | |
| Daniel Chen | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.39 per share. | 11 Aug 2020 | 950 | 117,468 (0%) | 0% | 1.4 | 1,321 | Common Stock |
| M. Kathleen Behrens Wilsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 357 | 63,214 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Jul 2020 | 39,803 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Jul 2020 | 39,803 | 535 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Jul 2020 | 39,803 | 39,803 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 535 | 535 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Jul 2020 | 535 | 535 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Jul 2020 | 535 | 0 (0%) | 0% | 0 | Common Stock | |
| Michael D. Loberg | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Jul 2020 | 39,803 | 39,803 (0%) | 0% | 0 | Common Stock | |
| Michael Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 178 | 356 (0%) | 0% | 0 | Common Stock | |
| Christina Teng Topsoe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 357 | 35,089 (0%) | 0% | 0 | Common Stock | |
| Jakob Haldor Topsoe | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2020 | 178 | 54,771 (0%) | 0% | 0 | Common Stock | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2020 | 150 | 2,250 | - | - | Stock Option (right to buy) | |
| Bruce Keyt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2020 | 2,837 | 6,242 | - | - | Stock Option (right to buy) |