Horizon Therapeutics Plc

XNAS: HZNP

Watchlist

Portfolio

Share
-

Market Cap

-

PE TTM

-

PEG TTM

-

Price to Book

-

Beta 1Year



Insider Trading disclosures for Horizon Therapeutics Plc

The latest disclosure was made by Jeff W. Himawan in Horizon Therapeutics Plc where a trade of 7,873 Ordinary Shares done was reported to US exchanges on May 9, 2023.

Insider trading is the trading of a company’s securities by individuals with access to confidential or material non-public information about the company. A company is required to report trading by corporate officers, directors, or other company members with significant access to privileged information to the Securities and Exchange Commission (SEC).

Client Name Client Category Action Reported to Exchange Quantity Post Transaction Holding Traded % Avg. Price Value Security Type
Jeff W. Himawan Director Gift of securities by or to the insider at price $ 0.00 per share. 09 May 2023 7,873 7,873 (0%) 0% 0 Ordinary Shares
Jeff W. Himawan Director Gift of securities by or to the insider at price $ 0.00 per share. 09 May 2023 7,873 2,121 (0%) 0% 0 Ordinary Shares
Gino Santini Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
Gino Santini Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 57,867 (0%) 0% - Ordinary Shares
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 19,361 (0%) 0% - Ordinary Shares
Thomas H. Watkins Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
Thomas H. Watkins Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 29,124 (0%) 0% - Ordinary Shares
Susan Mahony Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 3,913 (0%) 0% - Ordinary Shares
Susan Mahony Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.16 per share. 28 Apr 2023 1,879 2,034 (0%) 0% 111.2 208,870 Ordinary Shares
Susan Mahony Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
Jeff W. Himawan Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 11,873 (0%) 0% - Ordinary Shares
Jeff W. Himawan Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
Jeff W. Himawan Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.16 per share. 28 Apr 2023 1,879 9,994 (0%) 0% 111.2 208,870 Ordinary Shares
William F. Daniel Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 33,794 (0%) 0% - Ordinary Shares
William F. Daniel Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
William F. Daniel Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.16 per share. 28 Apr 2023 1,879 31,915 (0%) 0% 111.2 208,870 Ordinary Shares
James S. Shannon Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 23,185 (0%) 0% - Ordinary Shares
James S. Shannon Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.16 per share. 28 Apr 2023 1,879 21,306 (0%) 0% 111.2 208,870 Ordinary Shares
James S. Shannon Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
Pascale Witz Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 111.16 per share. 28 Apr 2023 1,879 16,323 (0%) 0% 111.2 208,870 Ordinary Shares
Pascale Witz Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 0 - - Restricted Stock Units
Pascale Witz Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2023 3,913 18,202 (0%) 0% - Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Gift of securities by or to the insider at price $ 0.00 per share. 13 Mar 2023 2,000 14,575 (0%) 0% 0 Common Stock
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 02 Mar 2023 3,629 0 - - Stock Option (Right to Buy)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 17.19 per share. 02 Mar 2023 743 126,558 (0%) 0% 17.2 12,772 Ordinary Shares
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 02 Mar 2023 743 0 - - Stock Option (Right to Buy)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.93 per share. 02 Mar 2023 3,629 125,815 (0%) 0% 14.9 54,181 Ordinary Shares
Sean M. Clayton EVP, General Counsel Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Mar 2023 14,129 28,258 - - Restricted Stock Units
Sean M. Clayton EVP, General Counsel Payment of exercise price or tax liability using portion of securities received from the company at price $ 110.34 per share. 01 Mar 2023 7,032 7,376 (0%) 0% 110.3 775,911 Ordinary Shares
Sean M. Clayton EVP, General Counsel Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Mar 2023 14,129 14,408 (0%) 0% - Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 17 Jan 2023 33,795 2,376 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 17 Jan 2023 33,795 83,109 (0%) 0% 0 Ordinary Shares
Andy Pasternak EVP, Chief Strategy Officer Sale of securities on an exchange or to another person at price $ 113.03 per share. 17 Jan 2023 27,129 56,338 (0%) 0% 113.0 3,066,323 Ordinary Shares
Aaron Cox EVP, Chief Financial Officer Sale of securities on an exchange or to another person at price $ 113.17 per share. 13 Jan 2023 36,148 277 (0%) 0% 113.2 4,090,847 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 113.05 per share. 10 Jan 2023 3,368 39,539 (0%) 0% 113.0 380,752 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 113.10 per share. 10 Jan 2023 3,368 36,171 (0%) 0% 113.1 380,921 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 18,397 18,397 - - Restricted Stock Units (RSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 51,132 65,562 (0%) 0% - Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.24 per share. 04 Jan 2023 22,655 42,907 (0%) 0% 113.2 2,565,452 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 113.29 per share. 04 Jan 2023 5,187 49,314 (0%) 0% 113.3 587,635 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 12,095 0 - - Restricted Stock Units (RSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 9,314 9,314 - - Restricted Stock Units (RSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 6,348 12,696 - - Restricted Stock Units (RSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 7,257 0 - - Performance Restricted Stock Units (PSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 1,966 0 - - Performance Restricted Stock Units (PSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 4,834 0 - - Performance Restricted Stock Units (PSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 9,318 4,654 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.24 per share. 04 Jan 2023 97,461 616,493 (0%) 0% 113.2 11,036,484 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 219,995 713,954 (0%) 0% - Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 39,944 17,448 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 23,200 0 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 9,435 0 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 34,835 0 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 24,598 49,198 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 34,928 34,929 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 58,055 0 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 20,697 20,697 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 71,290 71,290 - - Restricted Stock Units (RSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 12,095 0 - - Restricted Stock Units (RSUs)
Michael DesJardin EVP, Technical Operations Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.24 per share. 04 Jan 2023 26,901 122,186 (0%) 0% 113.2 3,046,269 Ordinary Shares
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 54,253 149,087 (0%) 0% - Ordinary Shares
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 7,257 0 - - Performance Restricted Stock Units (PSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 7,141 14,283 - - Restricted Stock Units (RSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 10,478 10,479 - - Restricted Stock Units (RSUs)
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 20,697 20,697 - - Restricted Stock Units (RSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 10,482 5,236 - - Performance Restricted Stock Units (PSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 4,834 0 - - Performance Restricted Stock Units (PSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 1,966 0 - - Performance Restricted Stock Units (PSUs)
Andy Pasternak EVP, Chief Strategy Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 22,997 22,997 - - Restricted Stock Units (RSU)
Elizabeth H.Z. Thompson EVP, Research & Development Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 20,697 20,697 - - Restricted Stock Units (RSU)
Aaron Cox EVP, Chief Financial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 22,997 22,997 - - Restricted Stock Units (RSU)
Sean M. Clayton EVP, General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 22,997 22,997 - - Restricted Stock Units (RSU)
Patrick McIlvenny Chief Accounting Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 7,973 10,463 (0%) 0% - Ordinary Shares
Patrick McIlvenny Chief Accounting Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 2,198 2,198 - - Restricted Stock Units (RSU)
Patrick McIlvenny Chief Accounting Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 3,871 0 - - Restricted Stock Units (RSU)
Patrick McIlvenny Chief Accounting Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2023 11,498 11,498 - - Restricted Stock Units (RSU)
Patrick McIlvenny Chief Accounting Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.24 per share. 04 Jan 2023 4,147 6,316 (0%) 0% 113.2 469,606 Ordinary Shares
Patrick McIlvenny Chief Accounting Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2023 1,904 3,809 - - Restricted Stock Units (RSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Jan 2023 21,772 24,147 (0%) 0% - Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Jan 2023 21,772 0 - - Performance Restricted Stock Units (PSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.80 per share. 01 Jan 2023 9,717 14,430 (0%) 0% 113.8 1,105,795 Ordinary Shares
Michael DesJardin EVP, Technical Operations Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.80 per share. 01 Jan 2023 9,561 94,834 (0%) 0% 113.8 1,088,042 Ordinary Shares
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Jan 2023 21,772 0 - - Performance Restricted Stock Units (PSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Jan 2023 21,772 104,395 (0%) 0% - Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 15,185 56,385 (0%) 0% - Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.80 per share. 30 Dec 2022 6,729 49,656 (0%) 0% 113.8 765,760 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 104,498 540,324 (0%) 0% - Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.80 per share. 30 Dec 2022 46,365 493,959 (0%) 0% 113.8 5,276,337 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 104,498 0 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 7,141 14,283 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 4,657 4,657 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 3,387 0 - - Restricted Stock Units (RSUs)
Jeff W. Himawan Director Gift of securities by or to the insider at price $ 0.00 per share. 30 Dec 2022 2,230 7,960 (0%) 0% 0 Ordinary Shares
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 88,733 122,780 (0%) 0% - Ordinary Shares
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 26,124 0 - - Performance Restricted Stock Units (PSU)
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 11,648 5,816 - - Performance Restricted Stock Units (PSU)
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 14,514 0 - - Restricted Stock Units (RSU)
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 11,643 11,643 - - Restricted Stock Units (RSU)
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 7,935 15,870 - - Restricted Stock Units (RSU)
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 5,800 0 - - Performance Restricted Stock Units (PSU)
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 2,360 0 - - Performance Restricted Stock Units (PSU)
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 8,709 0 - - Performance Restricted Stock Units (PSU)
Andy Pasternak EVP, Chief Strategy Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.80 per share. 30 Dec 2022 39,313 83,467 (0%) 0% 113.8 4,473,819 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 19,055 26,024 (0%) 0% - Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.80 per share. 30 Dec 2022 9,449 16,575 (0%) 0% 113.8 1,075,296 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 7,257 0 - - Restricted Stock Units (RSU)
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 4,657 4,657 - - Restricted Stock Units (RSU)
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 7,141 14,283 - - Restricted Stock Units (RSU)
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 9,318 4,654 - - Performance Restricted Stock Units (PSU)
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 7,935 15,870 - - Restricted Stock Units (RSU)
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 9,314 9,314 - - Restricted Stock Units (RSU)
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 9,676 0 - - Restricted Stock Units (RSU)
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 1,573 0 - - Performance Restricted Stock Units (PSU)
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 5,806 0 - - Performance Restricted Stock Units (PSU)
Aaron Cox EVP, Chief Financial Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 113.80 per share. 30 Dec 2022 28,758 36,425 (0%) 0% 113.8 3,272,660 Ordinary Shares
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 64,906 65,183 (0%) 0% - Ordinary Shares
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 17,416 0 - - Performance Restricted Stock Units (PSU)
Aaron Cox EVP, Chief Financial Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 30 Dec 2022 3,868 0 - - Performance Restricted Stock Units (PSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 21,772 21,772 - - Performance Restricted Stock Units (PSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 13,972 13,972 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 52,392 52,392 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 104,498 104,498 - - Performance Restricted Stock Units (PSUs)
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 21,772 21,772 - - Performance Restricted Stock Units (PSUs)
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 15,718 15,718 - - Performance Restricted Stock Units (PSUs)
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 277 82,623 (0%) 0% - Ordinary Shares
Andy Pasternak EVP, Chief Strategy Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 17,464 17,464 - - Performance Restricted Stock Units (PSUs)
Andy Pasternak EVP, Chief Strategy Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 26,124 26,124 - - Performance Restricted Stock Units (PSUs)
Aaron Cox EVP, Chief Financial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 277 5,051 (0%) 0% - Ordinary Shares
Aaron Cox EVP, Chief Financial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 13,972 13,972 - - Performance Restricted Stock Units (PSUs)
Aaron Cox EVP, Chief Financial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 27 Dec 2022 17,416 17,416 - - Performance Restricted Stock Units (PSUs)
Aaron Cox EVP, Chief Financial Officer Gift of securities by or to the insider at price $ 0.00 per share. 27 Dec 2022 4,774 277 (0%) 0% 0 Ordinary Shares
Andy Pasternak EVP, Chief Strategy Officer Sale of securities on an exchange or to another person at price $ 112.61 per share. 13 Dec 2022 23,251 40,965 (0%) 0% 112.6 2,618,207 Ordinary Shares
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 13 Dec 2022 23,251 0 - - Stock Option (Right to Buy)
Andy Pasternak EVP, Chief Strategy Officer Sale of securities on an exchange or to another person at price $ 112.60 per share. 13 Dec 2022 6,918 34,047 (0%) 0% 112.6 778,965 Ordinary Shares
Andy Pasternak EVP, Chief Strategy Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.52 per share. 13 Dec 2022 23,251 64,216 (0%) 0% 29.5 686,370 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 12 Dec 2022 8,531 61,475 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 111.45 per share. 12 Dec 2022 21,378 84,430 (0%) 0% 111.4 2,382,484 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 111.44 per share. 12 Dec 2022 6,974 54,501 (0%) 0% 111.4 777,208 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 12 Dec 2022 8,531 2,375 (0%) 0% 0 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 63.18 per share. 01 Nov 2022 5,503 40,965 (0%) 0% 63.2 347,680 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Nov 2022 12,421 0 - - Restricted Stock Units
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Nov 2022 12,421 46,468 (0%) 0% - Ordinary Shares
Sean M. Clayton EVP, General Counsel Purchase of securities on an exchange or from another person at price $ 66.67 per share. 04 Aug 2022 745 745 (0%) 0% 66.7 49,669 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 83.45 per share. 29 Jul 2022 643 34,047 (0%) 0% 83.4 53,658 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 82.44 per share. 29 Jul 2022 4,207 34,690 (0%) 0% 82.4 346,825 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Sale of securities on an exchange or to another person at price $ 85.00 per share. 19 Jul 2022 8 12,968 (0%) 0% 85 680 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Sale of securities on an exchange or to another person at price $ 85.00 per share. 19 Jul 2022 5,917 6,969 (0%) 0% 85 502,945 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Sale of securities on an exchange or to another person at price $ 85.04 per share. 19 Jul 2022 82 12,886 (0%) 0% 85.0 6,973 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Sale of securities on an exchange or to another person at price $ 85.01 per share. 07 Jul 2022 82 12,976 (0%) 0% 85.0 6,971 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 85.36 per share. 10 Jun 2022 762 38,897 (0%) 0% 85.4 65,044 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 92.08 per share. 03 Jun 2022 15,200 445,626 (0%) 0% 92.1 1,399,616 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 03 Jun 2022 25,000 742,565 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 92.74 per share. 03 Jun 2022 9,800 435,826 (0%) 0% 92.7 908,852 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 03 Jun 2022 25,000 460,826 (0%) 0% 22.1 553,500 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 93.21 per share. 31 May 2022 3,800 438,249 (0%) 0% 93.2 354,198 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 94.46 per share. 31 May 2022 2,700 435,549 (0%) 0% 94.5 255,042 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 92.04 per share. 31 May 2022 18,500 442,049 (0%) 0% 92.0 1,702,740 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 20 May 2022 25,000 767,565 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 90.00 per share. 20 May 2022 25,000 460,549 (0%) 0% 90 2,250,000 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 20 May 2022 25,000 485,549 (0%) 0% 22.1 553,500 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 90.00 per share. 11 May 2022 17,600 460,549 (0%) 0% 90 1,584,000 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 11 May 2022 17,600 792,565 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 11 May 2022 17,600 478,149 (0%) 0% 22.1 389,664 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 90.33 per share. 06 May 2022 2,400 465,549 (0%) 0% 90.3 216,792 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 06 May 2022 7,400 810,165 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 91.11 per share. 06 May 2022 5,000 460,549 (0%) 0% 91.1 455,550 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 06 May 2022 7,400 467,949 (0%) 0% 22.1 163,836 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 96.62 per share. 02 May 2022 7,608 463,999 (0%) 0% 96.6 735,085 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 97.43 per share. 02 May 2022 3,450 460,549 (0%) 0% 97.4 336,134 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 95.38 per share. 02 May 2022 13,942 471,607 (0%) 0% 95.4 1,329,788 Ordinary Shares
Gino Santini Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
Gino Santini Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 50,472 (0%) 0% - Ordinary Shares
Gino Santini Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 98.56 per share. 28 Apr 2022 1,658 48,814 (0%) 0% 98.6 163,412 Ordinary Shares
Gino Santini Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 66,513 (0%) 0% - Ordinary Shares
Michael G. Grey Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
Michael G. Grey Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 98.56 per share. 28 Apr 2022 1,139 65,374 (0%) 0% 98.6 112,260 Ordinary Shares
Thomas H. Watkins Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 75,164 (0%) 0% - Ordinary Shares
Thomas H. Watkins Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
Thomas H. Watkins Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
Susan Mahony Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
Susan Mahony Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
Susan Mahony Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 98.56 per share. 28 Apr 2022 1,658 16,617 (0%) 0% 98.6 163,412 Ordinary Shares
Susan Mahony Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 18,275 (0%) 0% - Ordinary Shares
Jeff W. Himawan Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 58,202 (0%) 0% - Ordinary Shares
Jeff W. Himawan Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
Jeff W. Himawan Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
Jeff W. Himawan Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 98.56 per share. 28 Apr 2022 1,139 57,063 (0%) 0% 98.6 112,260 Ordinary Shares
William F. Daniel Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 78,690 (0%) 0% - Ordinary Shares
William F. Daniel Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 98.56 per share. 28 Apr 2022 1,139 77,551 (0%) 0% 98.6 112,260 Ordinary Shares
William F. Daniel Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
William F. Daniel Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
James S. Shannon Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
James S. Shannon Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
James S. Shannon Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 98.56 per share. 28 Apr 2022 1,658 42,910 (0%) 0% 98.6 163,412 Ordinary Shares
James S. Shannon Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 44,568 (0%) 0% - Ordinary Shares
Pascale Witz Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 45,575 (0%) 0% - Ordinary Shares
Pascale Witz Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 98.56 per share. 28 Apr 2022 1,658 43,917 (0%) 0% 98.6 163,412 Ordinary Shares
Pascale Witz Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Apr 2022 3,913 3,913 - - Restricted Stock Units
Pascale Witz Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Apr 2022 4,223 0 - - Restricted Stock Units
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 109.39 per share. 22 Apr 2022 1,087 485,549 (0%) 0% 109.4 118,907 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 22 Apr 2022 25,000 510,549 (0%) 0% 22.1 553,500 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 107.94 per share. 22 Apr 2022 1,800 486,636 (0%) 0% 107.9 194,292 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 106.10 per share. 22 Apr 2022 16,413 494,136 (0%) 0% 106.1 1,741,419 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 107.02 per share. 22 Apr 2022 5,700 488,436 (0%) 0% 107.0 610,014 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 22 Apr 2022 25,000 817,565 - - Stock Option (Right to Buy)
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 20 Apr 2022 50,000 51,049 (0%) 0% 22.1 1,107,000 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 20 Apr 2022 50,000 36,424 - - Stock Option (Right to Buy)
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 115.17 per share. 20 Apr 2022 21,542 1,049 (0%) 0% 115.2 2,480,992 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 114.36 per share. 20 Apr 2022 28,458 22,591 (0%) 0% 114.4 3,254,457 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Sale of securities on an exchange or to another person at price $ 115.64 per share. 18 Apr 2022 8,098 13,058 (0%) 0% 115.6 936,453 Ordinary Shares
Michael DesJardin EVP, Technical Operations Sale of securities on an exchange or to another person at price $ 113.60 per share. 12 Apr 2022 11,064 82,346 (0%) 0% 113.6 1,256,870 Ordinary Shares
Michael DesJardin EVP, Technical Operations Sale of securities on an exchange or to another person at price $ 112.55 per share. 12 Apr 2022 9,150 93,410 (0%) 0% 112.6 1,029,833 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 08 Apr 2022 25,000 842,565 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 112.72 per share. 08 Apr 2022 16,687 485,549 (0%) 0% 112.7 1,880,959 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 111.70 per share. 08 Apr 2022 8,313 502,236 (0%) 0% 111.7 928,562 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 08 Apr 2022 25,000 510,549 (0%) 0% 22.1 553,500 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 110.02 per share. 06 Apr 2022 42,009 10,629 (0%) 0% 110.0 4,621,872 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 06 Apr 2022 185,060 216,384 (0%) 0% 22.1 4,097,228 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.96 per share. 06 Apr 2022 30,275 31,324 (0%) 0% 16.0 483,189 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 110.01 per share. 06 Apr 2022 215,335 1,049 (0%) 0% 110.0 23,688,788 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 110.01 per share. 06 Apr 2022 91,710 66,673 (0%) 0% 110.0 10,089,026 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 06 Apr 2022 30,275 0 - - Stock Option (Right to Buy)
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 06 Apr 2022 185,060 86,424 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 105.52 per share. 30 Mar 2022 35,480 485,549 (0%) 0% 105.5 3,743,850 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 104.61 per share. 30 Mar 2022 14,520 521,029 (0%) 0% 104.6 1,518,937 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 25 Mar 2022 25,000 560,549 (0%) 0% 22.1 553,500 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 109.37 per share. 25 Mar 2022 25,000 535,549 (0%) 0% 109.4 2,734,340 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 25 Mar 2022 25,000 867,565 - - Stock Option (Right to Buy)
Paul W. Hoelscher EVP, CFO Gift of securities by or to the insider at price $ 0.00 per share. 23 Mar 2022 66,626 245,015 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 23 Mar 2022 26,090 30,275 - - Stock Option (Right to Buy)
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 110.00 per share. 23 Mar 2022 663 158,383 (0%) 0% 110 72,930 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 110.00 per share. 23 Mar 2022 1,481 159,046 (0%) 0% 110 162,910 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 110.01 per share. 23 Mar 2022 11,699 160,527 (0%) 0% 110.0 1,287,018 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 110.00 per share. 23 Mar 2022 26,090 1,049 (0%) 0% 110.0 2,870,002 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.96 per share. 23 Mar 2022 26,090 27,139 (0%) 0% 16.0 416,396 Ordinary Shares
Paul W. Hoelscher EVP, CFO Gift of securities by or to the insider at price $ 0.00 per share. 23 Mar 2022 172,226 172,226 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Gift of securities by or to the insider at price $ 0.00 per share. 23 Mar 2022 172,226 72,789 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Gift of securities by or to the insider at price $ 0.00 per share. 23 Mar 2022 66,626 1,049 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 18 Mar 2022 12,304 50,062 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 18 Mar 2022 8,531 164,469 - - Stock Option (Right to Buy)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 18 Mar 2022 8,531 52,638 (0%) 0% 22.1 188,876 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 18 Mar 2022 8,169 52,944 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 18 Mar 2022 8,169 44,107 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 18 Mar 2022 5,287 52,276 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 18 Mar 2022 5,287 44,775 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 18 Mar 2022 12,304 46,989 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 11 Mar 2022 25,000 892,565 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 101.38 per share. 11 Mar 2022 6,662 535,549 (0%) 0% 101.4 675,394 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 100.77 per share. 11 Mar 2022 18,338 542,211 (0%) 0% 100.8 1,847,920 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 11 Mar 2022 25,000 560,549 (0%) 0% 22.1 553,500 Ordinary Shares
Michael DesJardin EVP, Technical Operations Sale of securities on an exchange or to another person at price $ 97.42 per share. 02 Mar 2022 13,518 102,560 (0%) 0% 97.4 1,316,924 Ordinary Shares
Michael DesJardin EVP, Technical Operations Sale of securities on an exchange or to another person at price $ 97.05 per share. 02 Mar 2022 21,482 116,078 (0%) 0% 97.0 2,084,828 Ordinary Shares
Sean M. Clayton EVP, General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 01 Mar 2022 42,387 42,387 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 93.57 per share. 25 Feb 2022 1,208 535,549 (0%) 0% 93.6 113,033 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 92.50 per share. 25 Feb 2022 2,900 536,757 (0%) 0% 92.5 268,250 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 91.54 per share. 25 Feb 2022 19,000 539,657 (0%) 0% 91.5 1,739,260 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 90.41 per share. 25 Feb 2022 26,892 558,657 (0%) 0% 90.4 2,431,306 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 92.51 per share. 25 Feb 2022 25,000 585,549 (0%) 0% 92.5 2,312,663 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 25 Feb 2022 25,000 610,549 (0%) 0% 22.1 553,500 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 25 Feb 2022 25,000 917,565 - - Stock Option (Right to Buy)
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 94.82 per share. 18 Feb 2022 1,313 39,659 (0%) 0% 94.8 124,499 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 94.33 per share. 01 Feb 2022 3,767 40,923 (0%) 0% 94.3 355,341 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Feb 2022 9,087 0 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Feb 2022 9,087 44,690 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 90.95 per share. 28 Jan 2022 14,541 671,008 (0%) 0% 91.0 1,322,504 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Jan 2022 25,000 967,565 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 28 Jan 2022 25,000 710,549 (0%) 0% 22.1 553,500 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 92.42 per share. 28 Jan 2022 11,206 585,549 (0%) 0% 92.4 1,035,659 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 91.94 per share. 28 Jan 2022 74,253 596,755 (0%) 0% 91.9 6,826,821 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 90.00 per share. 28 Jan 2022 25,000 685,549 (0%) 0% 90 2,250,000 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 5,354 0 - - Restricted Stock Units (RSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 86.42 per share. 21 Jan 2022 2,372 59,293 (0%) 0% 86.4 204,988 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 5,354 61,665 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 20,336 694,558 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 20,336 0 - - Restricted Stock Units (RSUs)
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 86.42 per share. 21 Jan 2022 9,009 685,549 (0%) 0% 86.4 778,558 Ordinary Shares
Michael DesJardin EVP, Technical Operations Payment of exercise price or tax liability using portion of securities received from the company at price $ 86.42 per share. 21 Jan 2022 1,825 137,560 (0%) 0% 86.4 157,717 Ordinary Shares
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 3,679 0 - - Restricted Stock Units (RSUs)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 3,679 139,385 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 5,558 0 - - Restricted Stock Units (RSUs)
Paul W. Hoelscher EVP, CFO Payment of exercise price or tax liability using portion of securities received from the company at price $ 86.42 per share. 21 Jan 2022 2,463 67,675 (0%) 0% 86.4 212,852 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Jan 2022 5,558 70,138 (0%) 0% 0 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Jan 2022 47,375 188,015 (0%) 0% 0 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Jan 2022 64,959 140,640 (0%) 0% - Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 05 Jan 2022 49,841 138,174 (0%) 0% 101.8 5,075,807 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Jan 2022 24,650 0 - - Restricted Stock Units (RSU)
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Jan 2022 12,095 12,095 - - Restricted Stock Units (RSU)
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Jan 2022 9,314 18,628 - - Restricted Stock Units (RSU)
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Jan 2022 9,222 9,223 - - Restricted Stock Units (RSU)
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Jan 2022 9,678 4,834 - - Restricted Stock Units (RSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 9,314 18,628 - - Restricted Stock Units (RSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 9,222 9,223 - - Restricted Stock Units (RSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 12,095 12,095 - - Restricted Stock Units (RSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 04 Jan 2022 50 37,758 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 12,261 0 - - Restricted Stock Units (RSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 52,570 61,685 (0%) 0% - Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 32,301 93,986 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. 04 Jan 2022 37,675 56,311 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 19,044 19,044 - - Restricted Stock Units (RSU)
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 04 Jan 2022 10,729 9,115 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 04 Jan 2022 10,729 37,808 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 9,678 4,834 - - Restricted Stock Units (RSU)
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 5,805 5,806 - - Restricted Stock Units (RSU)
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 8,992 0 - - Restricted Stock Units (RSU)
Miles W. Mchugh Sr VP & Princ. Acctg Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 7,617 7,617 - - Restricted Stock Units (RSU)
Miles W. Mchugh Sr VP & Princ. Acctg Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 04 Jan 2022 8,175 46,635 (0%) 0% 101.8 832,542 Ordinary Shares
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 18,289 54,810 (0%) 0% - Ordinary Shares
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 3,492 6,986 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 8,043 39,239 (0%) 0% - Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 04 Jan 2022 3,636 35,603 (0%) 0% 101.8 370,290 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 241,750 696,232 (0%) 0% - Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 04 Jan 2022 174,906 674,222 (0%) 0% 101.8 17,812,427 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 152,896 849,128 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 4,657 9,314 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 3,386 3,387 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 34,928 69,857 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 46,466 23,200 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 44,266 44,270 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 58,055 58,055 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 58,035 0 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 21,424 21,424 - - Restricted Stock Units (RSU)
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 73,796 73,796 - - Restricted Stock Units (RSU)
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 32,301 176,982 (0%) 0% 0 Ordinary Shares
Michael DesJardin EVP, Technical Operations Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 04 Jan 2022 41,276 135,706 (0%) 0% 101.8 4,203,548 Ordinary Shares
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 21,424 21,424 - - Restricted Stock Units (RSU)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 12,261 0 - - Restricted Stock Units (RSU)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 12,095 12,095 - - Restricted Stock Units (RSU)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 10,478 20,957 - - Restricted Stock Units (RSU)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 9,222 9,223 - - Restricted Stock Units (RSU)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 9,678 4,834 - - Restricted Stock Units (RSU)
Michael DesJardin EVP, Technical Operations Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 53,734 144,681 (0%) 0% - Ordinary Shares
Paul W. Hoelscher EVP, CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 9,522 9,522 - - Restricted Stock Units (RSU)
Paul W. Hoelscher EVP, CFO Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 04 Jan 2022 50,666 64,580 (0%) 0% 101.8 5,159,825 Ordinary Shares
Paul W. Hoelscher EVP, CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 47,375 115,246 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 66,822 67,871 (0%) 0% - Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 11,642 23,286 - - Restricted Stock Units (RSU)
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 11,616 5,800 - - Restricted Stock Units (RSU)
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 11,067 11,069 - - Restricted Stock Units (RSU)
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 14,514 14,514 - - Restricted Stock Units (RSU)
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 17,983 0 - - Restricted Stock Units (RSU)
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 100.23 per share. 04 Jan 2022 349 40,972 (0%) 0% 100.2 34,980 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 23,805 23,805 - - Restricted Stock Units (RSU)
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 11,642 23,286 - - Restricted Stock Units (RSU)
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 11,067 11,069 - - Restricted Stock Units (RSU)
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 11,616 5,800 - - Restricted Stock Units (RSU)
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 14,514 14,514 - - Restricted Stock Units (RSU)
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 48,839 70,669 (0%) 0% - Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 04 Jan 2022 21,710 48,959 (0%) 0% 101.8 2,210,946 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 97.30 per share. 04 Jan 2022 500 48,459 (0%) 0% 97.3 48,650 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 98.33 per share. 04 Jan 2022 700 47,759 (0%) 0% 98.3 68,831 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 99.85 per share. 04 Jan 2022 6,438 41,321 (0%) 0% 99.8 642,834 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 13,999 28,186 (0%) 0% - Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Jan 2022 21,424 21,424 - - Restricted Stock Units (RSU)
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 2,085 0 - - Restricted Stock Units (RSU)
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 7,257 7,257 - - Restricted Stock Units (RSU)
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Jan 2022 4,657 9,314 - - Restricted Stock Units (RSU)
Elizabeth H.Z. Thompson EVP, Research & Development Payment of exercise price or tax liability using portion of securities received from the company at price $ 101.84 per share. 04 Jan 2022 7,030 21,156 (0%) 0% 101.8 715,935 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.96 per share. 28 Dec 2021 8,575 9,624 (0%) 0% 16.0 136,857 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 110.00 per share. 28 Dec 2021 8,575 1,049 (0%) 0% 110 943,250 Ordinary Shares
Paul W. Hoelscher EVP, CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 28 Dec 2021 8,575 56,365 - - Stock Option (Right to Buy)
Paul W. Hoelscher EVP, CFO Gift of securities by or to the insider at price $ 0.00 per share. 28 Dec 2021 6,163 2,098 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Gift of securities by or to the insider at price $ 0.00 per share. 28 Dec 2021 1,049 1,049 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Gift of securities by or to the insider at price $ 0.00 per share. 28 Dec 2021 6,163 178,389 (0%) 0% 0 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 100.00 per share. 07 Dec 2021 1,525 21,830 (0%) 0% 100 152,500 Ordinary Shares
Miles W. Mchugh Sr VP & Princ. Acctg Officer Sale of securities on an exchange or to another person at price $ 106.62 per share. 01 Dec 2021 79,484 36,521 (0%) 0% 106.6 8,474,584 Ordinary Shares
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Dec 2021 79,484 0 - - Stock Option (Right to Buy)
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 01 Dec 2021 79,484 116,005 (0%) 0% 22.1 1,759,776 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 102.62 per share. 30 Nov 2021 15,875 517,969 (0%) 0% 102.6 1,629,093 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 103.54 per share. 30 Nov 2021 13,487 504,482 (0%) 0% 103.5 1,396,444 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 101.48 per share. 30 Nov 2021 20,638 533,844 (0%) 0% 101.5 2,094,344 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 112.60 per share. 04 Nov 2021 6,151 106,035 (0%) 0% 112.6 692,603 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Nov 2021 72,300 0 - - Stock Option (Right to Buy)
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Nov 2021 443 0 - - Stock Option (Right to Buy)
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Nov 2021 3,000 162,181 - - Stock Option (Right to Buy)
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 115.45 per share. 04 Nov 2021 5,724 75,681 (0%) 0% 115.5 660,836 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 114.43 per share. 04 Nov 2021 6,763 81,405 (0%) 0% 114.4 773,890 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 113.56 per share. 04 Nov 2021 17,867 88,168 (0%) 0% 113.6 2,028,977 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 111.75 per share. 04 Nov 2021 15,856 112,186 (0%) 0% 111.8 1,771,908 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 110.17 per share. 04 Nov 2021 23,382 128,042 (0%) 0% 110.2 2,575,995 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.48 per share. 04 Nov 2021 72,300 151,424 (0%) 0% 14.5 1,046,904 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.81 per share. 04 Nov 2021 443 79,124 (0%) 0% 11.8 5,232 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 04 Nov 2021 3,000 78,681 (0%) 0% 22.1 66,420 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 04 Nov 2021 23,251 23,251 - - Stock Option (Right to Buy)
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.52 per share. 04 Nov 2021 23,251 53,523 (0%) 0% 29.5 686,370 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 110.64 per share. 04 Nov 2021 5,484 48,039 (0%) 0% 110.6 606,750 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 111.47 per share. 04 Nov 2021 6,336 41,703 (0%) 0% 111.5 706,274 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 112.44 per share. 04 Nov 2021 2,706 38,997 (0%) 0% 112.4 304,263 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 113.54 per share. 04 Nov 2021 5,650 33,347 (0%) 0% 113.5 641,501 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 114.49 per share. 04 Nov 2021 2,728 30,619 (0%) 0% 114.5 312,329 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 115.51 per share. 04 Nov 2021 7,264 23,355 (0%) 0% 115.5 839,065 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Gift of securities by or to the insider at price $ 0.00 per share. 01 Nov 2021 100,300 100,300 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 120.09 per share. 01 Nov 2021 637 554,482 (0%) 0% 120.1 76,497 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 119.36 per share. 01 Nov 2021 9,733 555,119 (0%) 0% 119.4 1,161,731 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 118.46 per share. 01 Nov 2021 6,829 564,852 (0%) 0% 118.5 808,963 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 117.31 per share. 01 Nov 2021 7,801 571,681 (0%) 0% 117.3 915,135 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Gift of securities by or to the insider at price $ 0.00 per share. 01 Nov 2021 100,300 31,196 (0%) 0% 0 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Nov 2021 12,421 35,775 (0%) 0% - Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 118.29 per share. 01 Nov 2021 5,503 30,272 (0%) 0% 118.3 650,950 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Nov 2021 12,421 12,421 - - Restricted Stock Units
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 27 Oct 2021 10,729 0 - - Stock Option (Right to Buy)
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.61 per share. 27 Oct 2021 10,729 19,844 (0%) 0% 7.6 81,648 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Gift of securities by or to the insider at price $ 0.00 per share. 30 Sep 2021 110,502 131,496 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 112.01 per share. 30 Sep 2021 600 579,482 (0%) 0% 112.0 67,206 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 110.80 per share. 30 Sep 2021 18,940 580,082 (0%) 0% 110.8 2,098,552 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 109.96 per share. 30 Sep 2021 30,460 599,022 (0%) 0% 110.0 3,349,382 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Gift of securities by or to the insider at price $ 0.00 per share. 30 Sep 2021 110,502 629,482 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Gift of securities by or to the insider at price $ 0.00 per share. 30 Sep 2021 107,739 107,739 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Gift of securities by or to the insider at price $ 0.00 per share. 30 Sep 2021 107,739 739,984 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 21 Sep 2021 4,042 9,115 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 21 Sep 2021 46,271 10,729 - - Stock Option (Right to Buy)
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 110.00 per share. 21 Sep 2021 46,271 9,115 (0%) 0% 110 5,089,810 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.61 per share. 21 Sep 2021 46,271 55,386 (0%) 0% 7.6 352,122 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 21 Sep 2021 4,042 27,079 (0%) 0% 0 Ordinary Shares
Brian K. Beeler EVP, General Counsel Sale of securities on an exchange or to another person at price $ 107.91 per share. 17 Sep 2021 28,143 62,775 (0%) 0% 107.9 3,036,911 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 107.83 per share. 09 Sep 2021 22,754 23,850 (0%) 0% 107.8 2,453,564 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 09 Sep 2021 23,250 46,502 - - Stock Option (Right to Buy)
Andy Pasternak EVP and Chief Business Officer Sale of securities on an exchange or to another person at price $ 108.26 per share. 09 Sep 2021 496 23,354 (0%) 0% 108.3 53,697 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.52 per share. 09 Sep 2021 23,250 46,604 (0%) 0% 29.5 686,340 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 27 Aug 2021 7,435 1,042,565 - - Stock Option (Right to Buy)
Timothy P. Walbert Director, Chairman, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 27 Aug 2021 7,435 847,723 (0%) 0% 22.1 164,611 Ordinary Shares
Brian K. Beeler EVP, General Counsel Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 16 Aug 2021 65,857 165,816 (0%) 0% 22.1 1,458,074 Ordinary Shares
Brian K. Beeler EVP, General Counsel Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 16 Aug 2021 65,857 0 - - Stock Option (Right to Buy)
Brian K. Beeler EVP, General Counsel Sale of securities on an exchange or to another person at price $ 106.00 per share. 16 Aug 2021 74,898 90,918 (0%) 0% 106 7,939,188 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Sale of securities on an exchange or to another person at price $ 106.34 per share. 05 Aug 2021 7,542 14,187 (0%) 0% 106.3 802,025 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 102.50 per share. 28 Jul 2021 3,215 13,157 (0%) 0% 102.5 329,538 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 14,514 14,514 - - Performance Restricted Stock Units (PSUs)
Jeffrey W. Sherman EVP and Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 7,257 16,372 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 69,668 69,668 - - Performance Restricted Stock Units (PSUs)
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 102.57 per share. 28 Jul 2021 2,434 840,288 (0%) 0% 102.6 249,655 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 101.65 per share. 28 Jul 2021 22,566 842,722 (0%) 0% 101.7 2,293,834 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Payment of exercise price or tax liability using portion of securities received from the company at price $ 102.50 per share. 28 Jul 2021 15,432 865,288 (0%) 0% 102.5 1,581,780 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 34,833 880,720 (0%) 0% 0 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Gift of securities by or to the insider at price $ 0.00 per share. 28 Jul 2021 5,000 845,887 (0%) 0% 0 Ordinary Shares
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 7,257 94,544 (0%) 0% 0 Ordinary Shares
Michael DesJardin EVP, Technical Operations Payment of exercise price or tax liability using portion of securities received from the company at price $ 102.50 per share. 28 Jul 2021 3,599 90,945 (0%) 0% 102.5 368,898 Ordinary Shares
Michael DesJardin EVP, Technical Operations Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 14,514 14,514 - - Performance Restricted Stock Units (PSUs)
Paul W. Hoelscher EVP, CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 8,708 12,119 (0%) 0% 0 Ordinary Shares
Paul W. Hoelscher EVP, CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 17,418 17,418 - - Performance Restricted Stock Units (PSUs)
Paul W. Hoelscher EVP, CFO Payment of exercise price or tax liability using portion of securities received from the company at price $ 102.50 per share. 28 Jul 2021 3,858 8,261 (0%) 0% 102.5 395,445 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 7,257 78,896 (0%) 0% 0 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 14,514 14,514 - - Performance Restricted Stock Units (PSUs)
Barry J. Moze EVP, Chief Admin. Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 102.50 per share. 28 Jul 2021 3,215 75,681 (0%) 0% 102.5 329,538 Ordinary Shares
Brian K. Beeler EVP, General Counsel Payment of exercise price or tax liability using portion of securities received from the company at price $ 102.50 per share. 28 Jul 2021 2,573 99,959 (0%) 0% 102.5 263,733 Ordinary Shares
Brian K. Beeler EVP, General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 5,806 102,532 (0%) 0% 0 Ordinary Shares
Brian K. Beeler EVP, General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 11,612 11,612 - - Performance Restricted Stock Units (PSUs)
Andy Pasternak EVP and Chief Business Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 102.50 per share. 28 Jul 2021 3,858 23,354 (0%) 0% 102.5 395,445 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 8,708 27,212 (0%) 0% 0 Ordinary Shares
Andy Pasternak EVP and Chief Business Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 28 Jul 2021 17,418 17,418 - - Performance Restricted Stock Units (PSUs)
Michael G. Grey Director Sale of securities on an exchange or to another person at price $ 100.00 per share. 22 Jul 2021 1,000 4,000 (0%) 0% 100 100,000 Ordinary Shares
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 22 Jul 2021 5,000 0 - - Stock Option (Right to Buy)
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.37 per share. 22 Jul 2021 5,000 5,000 (0%) 0% 2.4 11,850 Ordinary Shares
Michael G. Grey Director Sale of securities on an exchange or to another person at price $ 100.05 per share. 22 Jul 2021 4,000 0 (0%) 0% 100.1 400,200 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 93.12 per share. 08 Jul 2021 14,626 71,639 (0%) 0% 93.1 1,361,973 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 92.64 per share. 08 Jul 2021 12,350 86,265 (0%) 0% 92.6 1,144,104 Ordinary Shares
Barry J. Moze EVP, Chief Admin. Officer Sale of securities on an exchange or to another person at price $ 91.35 per share. 08 Jul 2021 8,100 98,615 (0%) 0% 91.4 739,935 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 95.00 per share. 01 Jul 2021 5,287 9,115 (0%) 0% 95 502,265 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Sale of securities on an exchange or to another person at price $ 95.00 per share. 01 Jul 2021 54,789 128,845 (0%) 0% 95.0 5,205,097 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 01 Jul 2021 66,730 14,402 (0%) 0% 0 Ordinary Shares
Jeffrey W. Sherman EVP and Chief Medical Officer Gift of securities by or to the insider at price $ 0.00 per share. 01 Jul 2021 66,730 66,730 (0%) 0% 0 Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Jul 2021 12,077 27,717 (0%) 0% - Ordinary Shares
Elizabeth H.Z. Thompson EVP, Research & Development Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Jul 2021 12,077 0 - - Restricted Stock Units
Elizabeth H.Z. Thompson EVP, Research & Development Payment of exercise price or tax liability using portion of securities received from the company at price $ 96.59 per share. 01 Jul 2021 5,988 21,729 (0%) 0% 96.6 578,381 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 93.80 per share. 30 Jun 2021 23,592 852,295 (0%) 0% 93.8 2,212,930 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 94.78 per share. 30 Jun 2021 1,408 850,887 (0%) 0% 94.8 133,450 Ordinary Shares
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 10 Jun 2021 3,334 37,998 (0%) 0% - Ordinary Shares
Miles W. Mchugh Sr VP & Princ. Acctg Officer Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 10 Jun 2021 3,334 0 - - Restricted Stock Units (RSU)
Miles W. Mchugh Sr VP & Princ. Acctg Officer Payment of exercise price or tax liability using portion of securities received from the company at price $ 93.95 per share. 10 Jun 2021 1,477 36,521 (0%) 0% 93.9 138,764 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 91.00 per share. 01 Jun 2021 7,476 893,411 (0%) 0% 91 680,316 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 92.21 per share. 01 Jun 2021 17,524 875,887 (0%) 0% 92.2 1,615,888 Ordinary Shares
Paul W. Hoelscher EVP, CFO Sale of securities on an exchange or to another person at price $ 90.01 per share. 14 May 2021 102,925 172,226 (0%) 0% 90.0 9,263,847 Ordinary Shares
Jeffrey D. Kent See remarks Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 11 May 2021 12,592 43,408 - - Employee stock options (right to buy)
Jeffrey D. Kent See remarks Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.14 per share. 11 May 2021 12,592 83,586 (0%) 0% 22.1 278,787 Ordinary Shares
William F. Daniel Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.70 per share. 10 May 2021 20,000 20,000 (0%) 0% 12.7 254,000 Common Stock
William F. Daniel Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 10 May 2021 20,000 13,286 - - Stock Option (Right to Buy)
William F. Daniel Director Sale of securities on an exchange or to another person at price $ 87.01 per share. 10 May 2021 166 0 (0%) 0% 87.0 14,444 Common Stock
William F. Daniel Director Sale of securities on an exchange or to another person at price $ 86.56 per share. 10 May 2021 19,834 166 (0%) 0% 86.6 1,716,831 Common Stock
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 95.14 per share. 30 Apr 2021 20,872 899,838 (0%) 0% 95.1 1,985,762 Ordinary Shares
Timothy P. Walbert Director, Chairman, President and CEO Sale of securities on an exchange or to another person at price $ 94.15 per share. 30 Apr 2021 4,128 920,710 (0%) 0% 94.1 388,651 Ordinary Shares
Gino Santini Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 29 Apr 2021 4,223 4,223 - - Restricted Stock Units
Gino Santini Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 0 - - Restricted Stock Units
Gino Santini Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 50,606 (0%) 0% - Ordinary Shares
Gino Santini Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 94.62 per share. 29 Apr 2021 4,357 46,249 (0%) 0% 94.6 412,259 Ordinary Shares
Michael G. Grey Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 94.62 per share. 29 Apr 2021 2,993 70,395 (0%) 0% 94.6 283,198 Ordinary Shares
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 73,388 (0%) 0% - Ordinary Shares
Michael G. Grey Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 0 - - Restricted Stock Units
Michael G. Grey Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 29 Apr 2021 4,223 4,223 - - Restricted Stock Units
H. Thomas Watkins Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 0 - - Restricted Stock Units
H. Thomas Watkins Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 29 Apr 2021 4,223 4,223 - - Restricted Stock Units
H. Thomas Watkins Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 70,941 (0%) 0% - Ordinary Shares
Susan Mahony Director Payment of exercise price or tax liability using portion of securities received from the company at price $ 94.62 per share. 29 Apr 2021 4,357 14,052 (0%) 0% 94.6 412,259 Ordinary Shares
Susan Mahony Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 0 - - Restricted Stock Units
Susan Mahony Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 29 Apr 2021 4,223 4,223 - - Restricted Stock Units
Susan Mahony Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 18,409 (0%) 0% - Ordinary Shares
Jeff W. Himawan Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 0 - - Restricted Stock Units
Jeff W. Himawan Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 29 Apr 2021 4,223 4,223 - - Restricted Stock Units
Jeff W. Himawan Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 29 Apr 2021 11,098 53,979 (0%) 0% - Ordinary Shares
William F. Daniel Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 29 Apr 2021 4,223 4,223 - - Restricted Stock Units
*All Values are in $ Million
Client Category: Promoter/ KMP/ Director / Immediate Relatives / Employee / etc  
Security Type: Share/ Warrants / Convertible Debentures
Data as reported to USA Exchanges
View All The Insider Trades disclosures
Screeners based on Insider Trading and SAST parameters