34.90 0.50 (1.45%)
624.8K XNAS Volume
XNAS 20 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 03 Mar 2025 | 4,869 | 4,869 | - | 8.2 | 40,023 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 4,869 | 0 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 33.23 per share. | 03 Mar 2025 | 500 | 0 | - | 33.2 | 16,615 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 32.61 per share. | 03 Mar 2025 | 4,369 | 500 | - | 32.6 | 142,474 | Common Stock |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 2,500 | 2,500 | - | 0 | Common Stock | |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 10,400 | 10,400 | - | - | Restricted Stock Units | |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 36,500 | 36,500 | - | - | Stock Option | |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 2,500 | 7,500 | - | - | Restricted Stock Units | |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.01 per share. | 24 Jan 2025 | 865 | 1,635 | - | 38.0 | 32,879 | Common Stock |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 10,500 | 10,500 | - | 0 | Common Stock | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 52,000 | 52,000 | - | - | Restricted Stock Units | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 180,000 | 180,000 | - | - | Stock Option | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 10,500 | 31,500 | - | - | Restricted Stock Units | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.01 per share. | 24 Jan 2025 | 4,567 | 5,933 | - | 38.0 | 173,592 | Common Stock |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.01 per share. | 24 Jan 2025 | 2,037 | 1,775 | - | 38.0 | 77,426 | Common Stock |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,812 | 3,812 | - | 0 | Common Stock | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 18,900 | 18,900 | - | - | Restricted Stock Units | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 66,250 | 66,250 | - | - | Stock Option | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,812 | 11,438 | - | - | Restricted Stock Units | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 38.05 per share. | 24 Jan 2025 | 1,775 | 0 | - | 38.1 | 67,547 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 47,200 | 47,200 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 30.69 per share. | 24 Jan 2025 | 13,125 | 13,125 | - | 30.7 | 402,806 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 36.94 per share. | 24 Jan 2025 | 8,000 | 5,125 | - | 36.9 | 295,531 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 37.87 per share. | 24 Jan 2025 | 5,125 | 0 | - | 37.9 | 194,103 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 2,687 | 2,687 | - | 0 | Common Stock | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.01 per share. | 24 Jan 2025 | 1,058 | 1,629 | - | 38.0 | 40,215 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 38.02 per share. | 24 Jan 2025 | 1,629 | 0 | - | 38.0 | 61,941 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 13,125 | 39,375 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 2,687 | 8,063 | - | - | Restricted Stock Units | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 13,450 | 13,450 | - | - | Restricted Stock Units | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 37,400 | 37,400 | - | - | Stock Option | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 2,187 | 6,563 | - | - | Restricted Stock Units | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2025 | 10,650 | 10,650 | - | - | Restricted Stock Units | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 2,187 | 2,187 | - | 0 | Common Stock | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.01 per share. | 24 Jan 2025 | 1,151 | 1,036 | - | 38.0 | 43,750 | Common Stock |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Sale of securities on an exchange or to another person at price $ 40.13 per share. | 21 Jan 2025 | 19,293 | 0 | - | 40.1 | 774,245 | Common Stock |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Jan 2025 | 9,737 | 2,435 | - | - | Stock Option | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Jan 2025 | 3,470 | 20,000 | - | - | Stock Option | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Jan 2025 | 6,086 | 0 | - | - | Stock Option | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 21 Jan 2025 | 19,293 | 19,293 | - | 8.2 | 158,588 | Common Stock |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 40.18 per share. | 21 Jan 2025 | 25,000 | 0 | - | 40.2 | 1,004,598 | Common Stock |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Jan 2025 | 25,000 | 205,000 | - | - | Stock Option | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 29.03 per share. | 21 Jan 2025 | 25,000 | 25,000 | - | 29.0 | 725,750 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jan 2025 | 1,123 | 5,615 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 33.44 per share. | 16 Jan 2025 | 29,475 | 29,475 | - | 33.4 | 985,644 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 37.41 per share. | 16 Jan 2025 | 29,475 | 0 | - | 37.4 | 1,102,795 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 33.44 per share. | 16 Jan 2025 | 1,123 | 1,123 | - | 33.4 | 37,553 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 16 Jan 2025 | 1,123 | 0 | - | 40 | 44,920 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jan 2025 | 29,475 | 6,738 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 33.44 per share. | 15 Jan 2025 | 10,507 | 10,507 | - | 33.4 | 351,354 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 37.01 per share. | 15 Jan 2025 | 10,507 | 0 | - | 37.0 | 388,841 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2025 | 10,507 | 36,213 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 33.44 per share. | 13 Jan 2025 | 7,180 | 7,180 | - | 33.4 | 240,099 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 37.04 per share. | 13 Jan 2025 | 7,180 | 0 | - | 37.0 | 265,946 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Jan 2025 | 7,180 | 46,720 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 29 Oct 2024 | 21,496 | 21,496 | - | 24 | 515,904 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Oct 2024 | 21,496 | 28,972 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 40.47 per share. | 29 Oct 2024 | 21,496 | 0 | - | 40.5 | 870,018 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 35.62 per share. | 03 Oct 2024 | 705 | 0 | - | 35.6 | 25,111 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 35.05 per share. | 03 Oct 2024 | 35,652 | 705 | - | 35.0 | 1,249,435 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 01 Oct 2024 | 400 | 400 | - | 24 | 9,600 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Oct 2024 | 400 | 50,468 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 40.19 per share. | 01 Oct 2024 | 400 | 0 | - | 40.2 | 16,077 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2024 | 35,846 | 50,868 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 40.03 per share. | 30 Sep 2024 | 35,846 | 0 | - | 40.0 | 1,434,951 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 30 Sep 2024 | 35,846 | 35,846 | - | 24 | 860,304 | Common Stock |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2024 | 60,000 | 90,000 | - | - | Restricted Stock Units | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 40.00 per share. | 30 Sep 2024 | 32,052 | 27,948 | - | 40 | 1,282,080 | Common Stock |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2024 | 60,000 | 60,000 | - | 0 | Common Stock | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2024 | 60,000 | 90,000 | - | - | Restricted Stock Units | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 40.00 per share. | 30 Sep 2024 | 23,643 | 36,357 | - | 40 | 945,720 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2024 | 60,000 | 60,000 | - | 0 | Common Stock | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 27 Sep 2024 | 200 | 200 | - | 24 | 4,800 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Sep 2024 | 200 | 86,714 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 40.04 per share. | 27 Sep 2024 | 200 | 0 | - | 40.0 | 8,009 | Common Stock |
| R. Mark Graf | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2024 | 6,336 | 6,336 | - | - | Stock Option | |
| Gary L. Sender | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2024 | 11,657 | 11,657 | - | - | Stock Option | |
| Antonio Gracias | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2024 | 8,870 | 8,870 | - | - | Stock Option | |
| Jack Bech Nielsen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2024 | 6,336 | 6,336 | - | - | Stock Option | |
| Linda M. Szyper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2024 | 6,336 | 6,336 | - | - | Stock Option | |
| Juan A. Sabater | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2024 | 6,336 | 6,336 | - | - | Stock Option | |
| Peter Anastasiou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2024 | 6,336 | 6,336 | - | - | Stock Option | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2024 | 75,000 | 75,000 | - | - | Restricted Stock Units | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2024 | 75,000 | 75,000 | - | - | Stock Option | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Mar 2024 | 15,000 | 15,000 | - | 0 | Common Stock | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Mar 2024 | 15,000 | 15,000 | - | - | Restricted Stock Units | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.58 per share. | 29 Mar 2024 | 8,013 | 6,987 | - | 33.6 | 269,077 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 15 Mar 2024 | 11,979 | 11,979 | - | 8.2 | 98,467 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 32.00 per share. | 15 Mar 2024 | 11,979 | 0 | - | 32 | 383,328 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2024 | 9,644 | 4,869 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2024 | 2,335 | 0 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 32.00 per share. | 08 Mar 2024 | 194 | 0 | - | 32 | 6,208 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 08 Mar 2024 | 194 | 194 | - | 8.2 | 1,595 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2024 | 94 | 14,513 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2024 | 100 | 2,335 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 52,500 | 52,500 | - | - | Stock Option | |
| Kumar Budur | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 8,750 | 8,750 | - | - | Restricted Stock Units | |
| Serafin Andrew | CHIEF STRATEGY OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 47,750 | 47,750 | - | - | Stock Option | |
| S. Sandip Kapadia | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 74,250 | 74,250 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 10,750 | 10,750 | - | - | Restricted Stock Units | |
| Dayno Jeffrey M. | Director, PRESIDENT, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 202,250 | 202,250 | - | - | Stock Option | |
| Dayno Jeffrey M. | Director, PRESIDENT, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 42,000 | 42,000 | - | - | Restricted Stock Units | |
| Kapadia Sandip S. | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 15,250 | 15,250 | - | - | Restricted Stock Units | |
| Serafin Andrew | CHIEF STRATEGY OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 10,000 | 10,000 | - | - | Restricted Stock Unit | |
| Budur Kumar | CHIEF MEDICAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 42,500 | 42,500 | - | - | Stock Option | |
| Peter Anastasiou | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2023 | 6,771 | 6,771 | - | - | Stock Option | |
| Jeffrey M. Dayno | Director, PRESIDENT, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2023 | 125,000 | 125,000 | - | - | Stock Option | |
| R. Mark Graf | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 5,224 | 21,816 | - | - | Stock Option | |
| Gary L. Sender | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 9,613 | 48,255 | - | - | Stock Option | |
| Antonio Gracias | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 7,314 | 36,714 | - | - | Stock Option | |
| Jack Bech Nielsen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 5,224 | 26,224 | - | - | Stock Option | |
| Linda M. Szyper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 5,224 | 15,693 | - | - | Stock Option | |
| Juan A. Sabater | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 5,224 | 26,224 | - | - | Stock Option | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Mar 2023 | 30,000 | 30,000 | - | 0 | Common Stock | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Mar 2023 | 30,000 | 30,000 | - | - | Restricted Stock Units | |
| Sandip S. Kapadia | CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.36 per share. | 29 Mar 2023 | 15,414 | 14,586 | - | 33.4 | 514,211 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 60.13 per share. | 12 Dec 2022 | 6,320 | 2,148,073 | - | 60.1 | 380,022 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 60.00 per share. | 12 Dec 2022 | 130 | 2,147,943 | - | 60 | 7,800 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 60.36 per share. | 12 Dec 2022 | 22,391 | 2,154,393 | - | 60.4 | 1,351,521 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 61.23 per share. | 05 Dec 2022 | 77,853 | 2,176,784 | - | 61.2 | 4,766,939 | Common Stock |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Sale of securities on an exchange or to another person at price $ 60.12 per share. | 02 Dec 2022 | 37,080 | 920 | - | 60.1 | 2,229,246 | Common Stock |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Dec 2022 | 38,000 | 83,729 | - | - | Stock Option | |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Sale of securities on an exchange or to another person at price $ 60.71 per share. | 02 Dec 2022 | 920 | 0 | - | 60.7 | 55,854 | Common Stock |
| Andrew Serafin | CHIEF STRATEGY OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 02 Dec 2022 | 38,000 | 38,000 | - | 8.2 | 312,360 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 58.93 per share. | 29 Nov 2022 | 42,667 | 2,750,261 | - | 58.9 | 2,514,366 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 60.00 per share. | 29 Nov 2022 | 65,652 | 2,684,609 | - | 60 | 3,939,120 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 57.82 per share. | 29 Nov 2022 | 21,333 | 2,792,928 | - | 57.8 | 1,233,474 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 57.08 per share. | 18 Nov 2022 | 24,898 | 2,846,163 | - | 57.1 | 1,421,178 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 57.60 per share. | 18 Nov 2022 | 31,902 | 2,814,261 | - | 57.6 | 1,837,555 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 57.00 per share. | 18 Nov 2022 | 20,800 | 2,871,061 | - | 57 | 1,185,600 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 60.10 per share. | 14 Nov 2022 | 10,961 | 2,254,637 | - | 60.1 | 658,756 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 59.10 per share. | 14 Nov 2022 | 40,317 | 2,265,598 | - | 59.1 | 2,382,735 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 58.70 per share. | 11 Nov 2022 | 58,667 | 2,954,794 | - | 58.7 | 3,443,753 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 56.80 per share. | 11 Nov 2022 | 62,933 | 2,891,861 | - | 56.8 | 3,574,594 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 57.14 per share. | 11 Nov 2022 | 36,800 | 3,013,461 | - | 57.1 | 2,102,752 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 58.05 per share. | 08 Nov 2022 | 15,301 | 2,401,157 | - | 58.0 | 888,223 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 58.80 per share. | 08 Nov 2022 | 95,242 | 2,305,915 | - | 58.8 | 5,600,230 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 60.01 per share. | 08 Nov 2022 | 18,865 | 2,416,458 | - | 60.0 | 1,132,089 | Common Stock |
| Jeffrey M. Dayno | CHIEF MEDICAL OFFICER | Sale of securities on an exchange or to another person at price $ 60.02 per share. | 03 Nov 2022 | 15,000 | 0 | - | 60.0 | 900,332 | Common Stock |
| Jeffrey M. Dayno | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Nov 2022 | 15,000 | 23,470 | - | - | Stock Option | |
| Jeffrey M. Dayno | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 03 Nov 2022 | 15,000 | 15,000 | - | 8.2 | 123,300 | Common Stock |
| Jeffrey M. Dayno | CHIEF MEDICAL OFFICER | Sale of securities on an exchange or to another person at price $ 55.10 per share. | 01 Nov 2022 | 15,000 | 0 | - | 55.1 | 826,559 | Common Stock |
| Jeffrey M. Dayno | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2022 | 15,000 | 38,470 | - | - | Stock Option | |
| Jeffrey M. Dayno | CHIEF MEDICAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 01 Nov 2022 | 15,000 | 15,000 | - | 8.2 | 123,300 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 44.45 per share. | 03 Oct 2022 | 9,382 | 2,791 | - | 44.4 | 417,004 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Oct 2022 | 2,434 | 2,435 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Oct 2022 | 9,739 | 0 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 45.47 per share. | 03 Oct 2022 | 2,791 | 0 | - | 45.5 | 126,912 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 03 Oct 2022 | 12,173 | 12,173 | - | 8.2 | 100,062 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 46.95 per share. | 22 Aug 2022 | 26,650 | 2,321 | - | 47.0 | 1,251,332 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Aug 2022 | 28,971 | 86,914 | - | - | Stock Option | |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 47.56 per share. | 22 Aug 2022 | 2,321 | 0 | - | 47.6 | 110,395 | Common Stock |
| Jeffrey Dierks | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 22 Aug 2022 | 28,971 | 28,971 | - | 24 | 695,304 | Common Stock |
| John C. Jacobs | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Aug 2022 | 40,000 | 114,751 | - | - | Stock Option | |
| John C. Jacobs | Director, PRESIDENT, CEO | Sale of securities on an exchange or to another person at price $ 51.76 per share. | 15 Aug 2022 | 909 | 0 | - | 51.8 | 47,053 | Common Stock |
| John C. Jacobs | Director, PRESIDENT, CEO | Sale of securities on an exchange or to another person at price $ 51.05 per share. | 15 Aug 2022 | 39,091 | 909 | - | 51.1 | 1,995,760 | Common Stock |
| John C. Jacobs | Director, PRESIDENT, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 15 Aug 2022 | 40,000 | 40,000 | - | 8.2 | 328,800 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 52.61 per share. | 08 Aug 2022 | 71,447 | 3,012,090 | - | 52.6 | 3,758,827 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 53.67 per share. | 08 Aug 2022 | 20,745 | 3,083,537 | - | 53.7 | 1,113,384 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 53.94 per share. | 08 Aug 2022 | 486,360 | 3,104,282 | - | 53.9 | 26,234,258 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.30 per share. | 04 Aug 2022 | 60,000 | 3,240,261 | - | 52.3 | 3,138,000 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 53.56 per share. | 04 Aug 2022 | 75,000 | 3,050,261 | - | 53.6 | 4,017,000 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.42 per share. | 04 Aug 2022 | 115,000 | 3,125,261 | - | 52.4 | 6,028,300 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 52.67 per share. | 03 Aug 2022 | 12,640 | 3,620,124 | - | 52.7 | 665,749 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 52.57 per share. | 03 Aug 2022 | 29,482 | 3,590,642 | - | 52.6 | 1,549,869 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 52.90 per share. | 03 Aug 2022 | 30,464 | 3,632,764 | - | 52.9 | 1,611,546 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 55.22 per share. | 02 Aug 2022 | 75,117 | 3,300,261 | - | 55.2 | 4,147,961 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 55.19 per share. | 18 Jul 2022 | 40,087 | 3,375,378 | - | 55.2 | 2,212,402 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 55.01 per share. | 08 Jul 2022 | 3,058 | 3,421,238 | - | 55.0 | 168,221 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 55.07 per share. | 08 Jul 2022 | 7,710 | 3,424,296 | - | 55.1 | 424,590 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 55.26 per share. | 05 Jul 2022 | 87,417 | 3,612,844 | - | 55.3 | 4,830,663 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 56.01 per share. | 05 Jul 2022 | 180,838 | 3,432,006 | - | 56.0 | 10,128,736 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.27 per share. | 05 Jul 2022 | 32,486 | 3,700,261 | - | 52.3 | 1,698,043 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.04 per share. | 29 Jun 2022 | 11,038 | 3,732,747 | - | 52.0 | 574,418 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.20 per share. | 29 Jun 2022 | 3,533 | 3,743,785 | - | 52.2 | 184,423 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.37 per share. | 24 Jun 2022 | 86,209 | 3,750,044 | - | 52.4 | 4,514,765 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.10 per share. | 24 Jun 2022 | 2,726 | 3,747,318 | - | 52.1 | 142,025 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.06 per share. | 24 Jun 2022 | 11,528 | 3,836,253 | - | 52.1 | 600,148 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 45.38 per share. | 15 Jun 2022 | 14,200 | 800 | - | 45.4 | 644,370 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2022 | 15,000 | 154,751 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 46.13 per share. | 15 Jun 2022 | 800 | 0 | - | 46.1 | 36,907 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 15 Jun 2022 | 15,000 | 15,000 | - | 8.2 | 123,300 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 43.63 per share. | 13 Jun 2022 | 9,803 | 15,197 | - | 43.6 | 427,735 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Jun 2022 | 25,000 | 169,751 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 44.53 per share. | 13 Jun 2022 | 15,197 | 0 | - | 44.5 | 676,675 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 13 Jun 2022 | 25,000 | 25,000 | - | 8.2 | 205,500 | Common Stock |
| R. Mark Graf | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2022 | 4,742 | 4,742 | - | - | Stock Option | |
| Gary L. Sender | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2022 | 8,726 | 8,726 | - | - | Stock Option | |
| Antonio Gracias | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2022 | 6,639 | 6,639 | - | - | Stock Option | |
| Jack Bech Nielsen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2022 | 4,742 | 4,742 | - | - | Stock Option | |
| Linda M. Szyper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2022 | 4,742 | 4,742 | - | - | Stock Option | |
| Juan A. Sabater | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2022 | 4,742 | 4,742 | - | - | Stock Option | |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.19 per share. | 21 Apr 2022 | 6,554 | 3,847,781 | - | 52.2 | 342,053 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.14 per share. | 18 Apr 2022 | 30,177 | 3,854,335 | - | 52.1 | 1,573,429 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.14 per share. | 18 Apr 2022 | 4,195 | 3,982,398 | - | 52.1 | 218,727 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.35 per share. | 18 Apr 2022 | 97,886 | 3,884,512 | - | 52.3 | 5,124,332 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.05 per share. | 12 Apr 2022 | 2,486 | 10,741 | - | 50.0 | 124,424 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 52.08 per share. | 12 Apr 2022 | 13,668 | 3,986,593 | - | 52.1 | 711,829 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 51.15 per share. | 12 Apr 2022 | 75,465 | 4,000,261 | - | 51.2 | 3,860,035 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 51.15 per share. | 12 Apr 2022 | 10,741 | 0 | - | 51.1 | 549,402 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.05 per share. | 12 Apr 2022 | 17,469 | 4,075,726 | - | 50.0 | 874,323 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.25 per share. | 07 Apr 2022 | 4,610 | 4,098,359 | - | 50.3 | 231,653 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.09 per share. | 07 Apr 2022 | 5,164 | 4,093,195 | - | 50.1 | 258,665 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.09 per share. | 07 Apr 2022 | 735 | 13,227 | - | 50.1 | 36,816 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.25 per share. | 07 Apr 2022 | 656 | 13,962 | - | 50.3 | 32,964 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 04 Apr 2022 | 899 | 4,120,798 | - | 50 | 44,950 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.25 per share. | 04 Apr 2022 | 17,829 | 4,102,969 | - | 50.2 | 895,907 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.25 per share. | 04 Apr 2022 | 2,538 | 14,618 | - | 50.3 | 127,535 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 04 Apr 2022 | 128 | 17,156 | - | 50 | 6,400 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 49.36 per share. | 01 Apr 2022 | 6,765 | 7,706 | - | 49.4 | 333,893 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2022 | 14,471 | 116,085 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 49.87 per share. | 01 Apr 2022 | 7,706 | 0 | - | 49.9 | 384,277 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 01 Apr 2022 | 14,471 | 14,471 | - | 24 | 347,304 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.24 per share. | 30 Mar 2022 | 24,381 | 4,130,048 | - | 50.2 | 1,224,901 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 30 Mar 2022 | 2,079 | 4,121,697 | - | 50 | 103,950 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 30 Mar 2022 | 296 | 17,284 | - | 50 | 14,800 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.15 per share. | 30 Mar 2022 | 6,272 | 4,123,776 | - | 50.2 | 314,541 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.15 per share. | 30 Mar 2022 | 893 | 17,580 | - | 50.2 | 44,784 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.24 per share. | 30 Mar 2022 | 3,470 | 18,473 | - | 50.2 | 174,333 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.24 per share. | 25 Mar 2022 | 4,514 | 31,649 | - | 50.2 | 226,783 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.89 per share. | 25 Mar 2022 | 30,996 | 4,154,429 | - | 50.9 | 1,577,386 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.89 per share. | 25 Mar 2022 | 4,412 | 21,943 | - | 50.9 | 224,527 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.82 per share. | 25 Mar 2022 | 37,195 | 4,185,425 | - | 50.8 | 1,890,250 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.82 per share. | 25 Mar 2022 | 5,294 | 26,355 | - | 50.8 | 269,041 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.24 per share. | 25 Mar 2022 | 31,710 | 4,222,620 | - | 50.2 | 1,593,110 | Common Stock |
| Jeffrey S. Aronin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Mar 2022 | 1,180,599 | 1,180,599 | - | - | Stock Option | |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.13 per share. | 22 Mar 2022 | 5,757 | 4,280,345 | - | 50.1 | 288,598 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.12 per share. | 22 Mar 2022 | 16,576 | 4,254,330 | - | 50.1 | 830,789 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.12 per share. | 22 Mar 2022 | 2,359 | 36,163 | - | 50.1 | 118,233 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.25 per share. | 22 Mar 2022 | 9,439 | 4,270,906 | - | 50.3 | 474,310 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.25 per share. | 22 Mar 2022 | 1,344 | 38,522 | - | 50.3 | 67,536 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.13 per share. | 22 Mar 2022 | 819 | 39,866 | - | 50.1 | 41,056 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.10 per share. | 17 Mar 2022 | 9,003 | 4,286,097 | - | 50.1 | 451,050 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.10 per share. | 17 Mar 2022 | 1,282 | 40,685 | - | 50.1 | 64,228 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.05 per share. | 17 Mar 2022 | 5,161 | 4,295,100 | - | 50.0 | 258,308 | Common Stock |
| Jack Bech Nielsen | Director | Sale of securities on an exchange or to another person at price $ 50.05 per share. | 17 Mar 2022 | 735 | 41,967 | - | 50.1 | 36,787 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 45.32 per share. | 16 Mar 2022 | 15,000 | 0 | - | 45.3 | 679,821 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 16 Mar 2022 | 15,000 | 15,000 | - | 8.2 | 123,300 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Mar 2022 | 15,000 | 194,751 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 42.66 per share. | 14 Mar 2022 | 11,614 | 930 | - | 42.7 | 495,474 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 14 Mar 2022 | 25,000 | 25,000 | - | 8.2 | 205,500 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 42.06 per share. | 14 Mar 2022 | 12,456 | 12,544 | - | 42.1 | 523,871 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2022 | 25,000 | 209,751 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 43.47 per share. | 14 Mar 2022 | 930 | 0 | - | 43.5 | 40,427 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 40.52 per share. | 01 Mar 2022 | 328,927 | 4,123,815 | - | 40.5 | 13,328,122 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 41.01 per share. | 01 Mar 2022 | 175,000 | 3,948,815 | - | 41.0 | 7,176,750 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 40.24 per share. | 01 Mar 2022 | 92,501 | 4,452,742 | - | 40.2 | 3,722,240 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 28 Feb 2022 | 10,041 | 0 | - | 40.0 | 401,653 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2022 | 4,869 | 14,607 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2022 | 10,041 | 130,556 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 40.04 per share. | 28 Feb 2022 | 4,869 | 0 | - | 40.0 | 194,958 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 28 Feb 2022 | 4,869 | 4,869 | - | 8.2 | 40,023 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 28 Feb 2022 | 10,041 | 10,041 | - | 24 | 240,984 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 40.05 per share. | 16 Feb 2022 | 4,259 | 0 | - | 40.1 | 170,591 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2022 | 200 | 140,397 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2022 | 4,259 | 140,597 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 40.02 per share. | 16 Feb 2022 | 4,259 | 0 | - | 40.0 | 170,424 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 16 Feb 2022 | 200 | 200 | - | 24 | 4,800 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 16 Feb 2022 | 4,259 | 4,259 | - | 24 | 102,216 | Common Stock |
| Jeffrey Dierks | Director, Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 39.60 per share. | 06 Jan 2022 | 1,399 | 4,726 | - | 39.6 | 55,396 | Common Stock |
| Jeffrey Dierks | Director, Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jan 2022 | 2,435 | 4,869 | - | - | Stock Option | |
| Jeffrey Dierks | Director, Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jan 2022 | 3,690 | 9,739 | - | - | Stock Option | |
| Jeffrey Dierks | Director, Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 41.23 per share. | 06 Jan 2022 | 424 | 0 | - | 41.2 | 17,482 | Common Stock |
| Jeffrey Dierks | Director, Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 40.53 per share. | 06 Jan 2022 | 4,302 | 424 | - | 40.5 | 174,379 | Common Stock |
| Jeffrey Dierks | Director, Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 06 Jan 2022 | 6,125 | 6,125 | - | 8.2 | 50,348 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 03 Jan 2022 | 18,053 | 18,053 | - | 8.2 | 148,396 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2022 | 18,053 | 234,751 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2022 | 10,647 | 252,804 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 03 Jan 2022 | 10,647 | 10,647 | - | 8.2 | 87,518 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 45.15 per share. | 03 Jan 2022 | 18,053 | 0 | - | 45.1 | 815,050 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 45.17 per share. | 03 Jan 2022 | 10,647 | 0 | - | 45.2 | 480,936 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 45.03 per share. | 27 Dec 2021 | 1,300 | 0 | - | 45.0 | 58,538 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2021 | 1,300 | 263,451 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 27 Dec 2021 | 1,300 | 1,300 | - | 8.2 | 10,686 | Common Stock |
| Jeffrey S. Aronin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.00 per share. | 14 Dec 2021 | 251,922 | 251,922 | - | 24 | 6,046,128 | Common Stock |
| Jeffrey S. Aronin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2021 | 251,922 | 1,007,689 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 13 Dec 2021 | 25,000 | 25,000 | - | 8.2 | 205,500 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2021 | 25,000 | 264,751 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 38.43 per share. | 13 Dec 2021 | 11,860 | 0 | - | 38.4 | 455,780 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 38.02 per share. | 13 Dec 2021 | 13,140 | 11,860 | - | 38.0 | 499,629 | Common Stock |
| Linda M. Szyper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2021 | 5,727 | 5,727 | - | - | Stock Option | |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 41.09 per share. | 15 Nov 2021 | 32,251 | 4,573,928 | - | 41.1 | 1,325,194 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 41.25 per share. | 15 Nov 2021 | 1,417 | 4,572,511 | - | 41.2 | 58,451 | Common Stock |
| Andreas Wicki | Director | Sale of securities on an exchange or to another person at price $ 42.08 per share. | 15 Nov 2021 | 35,600 | 4,609,179 | - | 42.1 | 1,498,048 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 42.44 per share. | 01 Nov 2021 | 2,946 | 0 | - | 42.4 | 125,015 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2021 | 3,952 | 19,476 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2021 | 6,048 | 13,429 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 41.36 per share. | 01 Nov 2021 | 7,054 | 2,946 | - | 41.4 | 291,725 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 01 Nov 2021 | 10,000 | 10,000 | - | 8.2 | 82,200 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 19 Oct 2021 | 14,099 | 14,099 | - | 8.2 | 115,894 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Oct 2021 | 4,101 | 53,469 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Oct 2021 | 14,099 | 57,570 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 43.77 per share. | 19 Oct 2021 | 4,101 | 0 | - | 43.8 | 179,507 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 19 Oct 2021 | 4,101 | 4,101 | - | 8.2 | 33,710 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 43.13 per share. | 19 Oct 2021 | 14,099 | 0 | - | 43.1 | 608,036 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 06 Oct 2021 | 1,800 | 1,800 | - | 8.2 | 14,796 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Oct 2021 | 1,800 | 71,669 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 40.10 per share. | 06 Oct 2021 | 1,800 | 0 | - | 40.1 | 72,179 | Common Stock |
| John C. Jacobs | Director, President, CEO | Sale of securities on an exchange or to another person at price $ 35.93 per share. | 13 Sep 2021 | 25,000 | 0 | - | 35.9 | 898,263 | Common Stock |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Sep 2021 | 25,000 | 289,751 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 13 Sep 2021 | 25,000 | 25,000 | - | 8.2 | 205,500 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 07 Sep 2021 | 10,000 | 10,000 | - | 8.2 | 82,200 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 37.58 per share. | 07 Sep 2021 | 10,000 | 0 | - | 37.6 | 375,783 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Sep 2021 | 10,000 | 73,469 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Sep 2021 | 4,083 | 7,304 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 07 Sep 2021 | 5,000 | 5,000 | - | 8.2 | 41,100 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 37.00 per share. | 07 Sep 2021 | 5,000 | 0 | - | 37 | 185,000 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Sep 2021 | 917 | 23,428 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 34.26 per share. | 01 Sep 2021 | 3,302 | 0 | - | 34.3 | 113,115 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 33.30 per share. | 01 Sep 2021 | 6,698 | 3,302 | - | 33.3 | 223,010 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 01 Sep 2021 | 10,000 | 10,000 | - | 8.2 | 82,200 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | 01 Sep 2021 | 10,000 | 18,692 | - | - | Stock Option | ||
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 26 Aug 2021 | 7,841 | 7,841 | - | 8.2 | 64,453 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 26 Aug 2021 | 2,159 | 2,159 | - | 8.2 | 17,747 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 35.01 per share. | 26 Aug 2021 | 2,159 | 0 | - | 35.0 | 75,581 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2021 | 7,841 | 83,469 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2021 | 2,159 | 91,310 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 35.16 per share. | 26 Aug 2021 | 7,841 | 0 | - | 35.2 | 275,701 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 35.01 per share. | 26 Aug 2021 | 1,600 | 0 | - | 35.0 | 56,021 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2021 | 3,400 | 28,692 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2021 | 1,600 | 32,092 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 35.18 per share. | 26 Aug 2021 | 3,400 | 0 | - | 35.2 | 119,604 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 26 Aug 2021 | 3,400 | 3,400 | - | 8.2 | 27,948 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 26 Aug 2021 | 1,600 | 1,600 | - | 8.2 | 13,152 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 30.21 per share. | 10 Aug 2021 | 9,950 | 0 | - | 30.2 | 300,634 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2021 | 9,950 | 93,469 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 10 Aug 2021 | 9,950 | 9,950 | - | 8.2 | 81,789 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 22 Jul 2021 | 50 | 0 | - | 30 | 1,500 | Common Stock |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Jul 2021 | 50 | 103,419 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 22 Jul 2021 | 50 | 50 | - | 8.2 | 411 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 31.32 per share. | 15 Jun 2021 | 15,000 | 0 | - | 31.3 | 469,806 | Common Stock |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2021 | 15,000 | 33,692 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 15 Jun 2021 | 15,000 | 15,000 | - | 8.2 | 123,300 | Common Stock |
| R. Mark Graf | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 7,246 | 7,246 | - | - | Stock Option | |
| Juan A. Sabater | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 7,246 | 7,246 | - | - | Stock Option | |
| R. Mark Graf | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Nov 2020 | 4,604 | 4,604 | - | - | Stock Option | |
| Eric Motley | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Nov 2020 | 4,604 | 4,604 | - | - | Stock Option | |
| Jack B. Nielsen | Director | Purchase of securities on an exchange or from another person at price $ 34.30 per share. | 25 Aug 2020 | 3,922 | 42,702 | - | 34.3 | 134,525 | Common Stock |
| Jack B. Nielsen | Director | Purchase of securities on an exchange or from another person at price $ 34.20 per share. | 25 Aug 2020 | 823 | 38,780 | - | 34.2 | 28,147 | Common Stock |
| Andrew Serafin | Chief Business Officer | 21 Aug 2020 | 51,021 | 0 | - | - | Series C Preferred Stock | ||
| Andrew Serafin | Chief Business Officer | 21 Aug 2020 | 200,000 | 0 | - | - | Series A Preferred Stock | ||
| Andrew Serafin | Chief Business Officer | 21 Aug 2020 | 33,693 | 33,693 | - | - | Common Stock | ||
| Jack B. Nielsen | Director | Purchase of securities on an exchange or from another person at price $ 35.00 per share. | 20 Aug 2020 | 2,736 | 2,736 | - | 35 | 95,760 | Common Stock |
| Jack B. Nielsen | Director | Purchase of securities on an exchange or from another person at price $ 34.30 per share. | 20 Aug 2020 | 3,057 | 37,957 | - | 34.3 | 104,855 | Common Stock |
| Jack B. Nielsen | Director | Purchase of securities on an exchange or from another person at price $ 34.10 per share. | 20 Aug 2020 | 7,352 | 34,900 | - | 34.1 | 250,703 | Common Stock |
| Jack B. Nielsen | Director | Purchase of securities on an exchange or from another person at price $ 24.00 per share. | 20 Aug 2020 | 24,812 | 27,548 | - | 24 | 595,488 | Common Stock |
| Jeffrey S. Aronin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 1,259,611 | 1,259,611 | - | - | Stock Option | |
| Gary L. Sender | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 16,583 | 16,583 | - | - | Stock Option | |
| Antonio Gracias | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 12,617 | 12,617 | - | - | Stock Option | |
| Jeffrey M. Dayno | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 132,260 | 132,260 | - | - | Stock Option | |
| Jack B. Nielsen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 9,012 | 9,012 | - | - | Stock Option | |
| John C. Jacobs | Director, President, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 144,856 | 144,856 | - | - | Stock Option | |
| Jeffrey Dierks | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 144,856 | 144,856 | - | - | Stock Option | |
| Andrew Serafin | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 81,875 | 81,875 | - | - | Stock Option | |
| Juan A. Sabater | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2020 | 9,012 | 9,012 | - | - | Stock Option |