Insider Trading disclosures for Frequency Therapeutics Inc

The latest disclosure was made by David L. Lucchino in Frequency Therapeutics Inc where a trade of 3,057 Common Stock done at an average price of $0.5 was reported to US exchanges on Aug. 18, 2023.

Insider trading is the trading of a company’s securities by individuals with access to confidential or material non-public information about the company. A company is required to report trading by corporate officers, directors, or other company members with significant access to privileged information to the Securities and Exchange Commission (SEC).

Client Name	Client Category	Action	Reported to Exchange	Quantity	Post Transaction Holding	Traded %	Avg. Price	Value	Security Type
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.50 per share.	18 Aug 2023	3,057	633,744 (2%)	0%	0.5	1,529	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.60 per share.	18 Aug 2023	2,865	636,801 (2%)	0%	0.6	1,719	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.63 per share.	18 Aug 2023	227	48,694 (0%)	0%	0.6	143	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.53 per share.	18 Aug 2023	237	48,457 (0%)	0%	0.5	126	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.65 per share.	16 Aug 2023	2,895	642,399 (2%)	0%	0.7	1,882	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.63 per share.	16 Aug 2023	2,733	639,666 (2%)	0%	0.6	1,722	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.62 per share.	16 Aug 2023	230	48,921 (0%)	0%	0.6	143	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.67 per share.	16 Aug 2023	234	49,151 (0%)	0%	0.7	157	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.63 per share.	14 Aug 2023	2,881	647,923 (2%)	0%	0.6	1,815	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.67 per share.	14 Aug 2023	2,629	645,294 (2%)	0%	0.7	1,761	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.64 per share.	14 Aug 2023	238	49,613 (0%)	0%	0.6	152	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.65 per share.	14 Aug 2023	228	49,385 (0%)	0%	0.6	148	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.68 per share.	10 Aug 2023	2,790	653,537 (2%)	0%	0.7	1,897	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.67 per share.	10 Aug 2023	2,733	650,804 (2%)	0%	0.7	1,831	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.64 per share.	10 Aug 2023	240	49,851 (0%)	0%	0.6	154	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.64 per share.	10 Aug 2023	247	50,091 (0%)	0%	0.6	158	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.69 per share.	08 Aug 2023	2,810	659,125 (2%)	0%	0.7	1,939	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.67 per share.	08 Aug 2023	2,798	656,327 (2%)	0%	0.7	1,875	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.66 per share.	08 Aug 2023	238	50,338 (0%)	0%	0.7	157	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.67 per share.	08 Aug 2023	241	50,576 (0%)	0%	0.7	161	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.68 per share.	04 Aug 2023	2,857	661,935 (2%)	0%	0.7	1,943	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.69 per share.	04 Aug 2023	2,550	664,792 (2%)	0%	0.7	1,760	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.69 per share.	04 Aug 2023	235	50,817 (0%)	0%	0.7	162	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.67 per share.	04 Aug 2023	220	51,052 (0%)	0%	0.7	147	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.52 per share.	02 Aug 2023	2,587	670,021 (2%)	0%	0.5	1,345	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.59 per share.	02 Aug 2023	2,679	667,342 (2%)	0%	0.6	1,581	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.56 per share.	02 Aug 2023	232	51,272 (0%)	0%	0.6	130	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.49 per share.	02 Aug 2023	231	51,504 (0%)	0%	0.5	113	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.50 per share.	31 Jul 2023	2,676	675,407 (2%)	0%	0.5	1,338	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.49 per share.	31 Jul 2023	2,799	672,608 (2%)	0%	0.5	1,372	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.48 per share.	31 Jul 2023	238	51,735 (0%)	0%	0.5	114	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.50 per share.	31 Jul 2023	222	51,973 (0%)	0%	0.5	111	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.51 per share.	27 Jul 2023	2,791	680,730 (2%)	0%	0.5	1,423	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.47 per share.	27 Jul 2023	2,647	678,083 (2%)	0%	0.5	1,244	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.46 per share.	27 Jul 2023	1,344	183,650 (0%)	0%	0.5	618	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.53 per share.	27 Jul 2023	1,373	184,994 (0%)	0%	0.5	728	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.47 per share.	27 Jul 2023	223	52,195 (0%)	0%	0.5	105	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.53 per share.	27 Jul 2023	227	52,418 (0%)	0%	0.5	120	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.52 per share.	25 Jul 2023	2,609	683,521 (2%)	0%	0.5	1,357	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.50 per share.	25 Jul 2023	2,803	686,130 (2%)	0%	0.5	1,402	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.51 per share.	25 Jul 2023	1,329	186,367 (0%)	0%	0.5	678	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.50 per share.	25 Jul 2023	1,390	187,696 (0%)	0%	0.5	695	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.53 per share.	25 Jul 2023	222	52,645 (0%)	0%	0.5	118	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.50 per share.	25 Jul 2023	234	52,867 (0%)	0%	0.5	117	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.54 per share.	21 Jul 2023	2,887	688,933 (2%)	0%	0.5	1,559	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.61 per share.	21 Jul 2023	2,663	691,820 (2%)	0%	0.6	1,624	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.61 per share.	21 Jul 2023	1,333	190,524 (0%)	0%	0.6	813	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.54 per share.	21 Jul 2023	1,438	189,086 (0%)	0%	0.5	777	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.61 per share.	21 Jul 2023	223	53,335 (0%)	0%	0.6	136	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.56 per share.	21 Jul 2023	234	53,101 (0%)	0%	0.6	131	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.65 per share.	19 Jul 2023	2,646	697,193 (2%)	0%	0.7	1,720	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.64 per share.	19 Jul 2023	2,710	694,483 (2%)	0%	0.6	1,734	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.64 per share.	19 Jul 2023	1,361	191,857 (0%)	0%	0.6	871	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.65 per share.	19 Jul 2023	1,335	193,218 (0%)	0%	0.7	868	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.64 per share.	19 Jul 2023	229	53,558 (0%)	0%	0.6	147	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.63 per share.	19 Jul 2023	228	53,787 (0%)	0%	0.6	144	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.68 per share.	17 Jul 2023	2,775	702,807 (2%)	0%	0.7	1,887	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.56 per share.	17 Jul 2023	2,968	699,839 (2%)	0%	0.6	1,662	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.56 per share.	17 Jul 2023	1,484	194,553 (0%)	0%	0.6	831	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.67 per share.	17 Jul 2023	1,415	196,037 (0%)	0%	0.7	948	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.56 per share.	17 Jul 2023	249	54,015 (0%)	0%	0.6	139	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.65 per share.	17 Jul 2023	244	54,264 (0%)	0%	0.7	159	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.59 per share.	13 Jul 2023	1,815	705,582 (2%)	0%	0.6	1,071	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.39 per share.	13 Jul 2023	2,646	707,397 (2%)	0%	0.4	1,032	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.39 per share.	13 Jul 2023	1,329	198,358 (0%)	0%	0.4	518	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.59 per share.	13 Jul 2023	906	197,452 (0%)	0%	0.6	535	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.60 per share.	13 Jul 2023	148	54,508 (0%)	0%	0.6	89	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.39 per share.	13 Jul 2023	227	54,656 (0%)	0%	0.4	89	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.39 per share.	11 Jul 2023	2,649	710,043 (2%)	0%	0.4	1,033	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.37 per share.	11 Jul 2023	2,731	712,692 (2%)	0%	0.4	1,010	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.37 per share.	11 Jul 2023	1,363	201,022 (0%)	0%	0.4	504	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.39 per share.	11 Jul 2023	1,335	199,687 (0%)	0%	0.4	521	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.40 per share.	11 Jul 2023	220	54,883 (0%)	0%	0.4	88	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.37 per share.	11 Jul 2023	228	55,103 (0%)	0%	0.4	84	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.38 per share.	07 Jul 2023	2,591	715,423 (2%)	0%	0.4	985	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.35 per share.	07 Jul 2023	2,634	718,014 (2%)	0%	0.4	922	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.36 per share.	07 Jul 2023	1,306	203,689 (0%)	0%	0.4	470	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.37 per share.	07 Jul 2023	1,304	202,385 (0%)	0%	0.4	482	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.37 per share.	07 Jul 2023	220	55,331 (0%)	0%	0.4	81	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.36 per share.	07 Jul 2023	220	55,551 (0%)	0%	0.4	79	Common Stock
Christopher R. Loose	Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Jul 2023	150,000	200,050 (0%)	0%		-	Common Stock
Christopher R. Loose	Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Jul 2023	150,000	0	-		-	Restricted Stock Unit
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 0.34 per share.	04 Jul 2023	1,384	198,666 (0%)	0%	0.3	471	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 0.35 per share.	04 Jul 2023	224	55,771 (0%)	0%	0.3	78	Common Stock
Richard M. Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Jul 2023	25,000	55,995 (0%)	0%		-	Common Stock
Richard M. Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Jul 2023	25,000	0	-		-	Restricted Stock Unit
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Feb 2023	300,000	723,421 (2%)	0%		-	Common Stock
David L. Lucchino	Director, President and CEO	Gift of securities by or to the insider at price $ 0.00 per share.	01 Feb 2023	33,345	423,421 (1%)	0%		0	Common Stock
David L. Lucchino	Director, President and CEO	Gift of securities by or to the insider at price $ 0.00 per share.	01 Feb 2023	13,345	456,766 (1%)	0%		0	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Feb 2023	300,000	0	-		-	Restricted Stock Units
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 0.34 per share.	01 Feb 2023	2,773	720,648 (2%)	0%	0.3	943	Common Stock
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	91,000	91,000	-		-	Restricted Stock Unit
Wendy S. Arnold	Chief People Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	91,000	91,000	-		-	Restricted Stock Unit
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	280,000	280,000	-		-	Restricted Stock Unit
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	105,000	105,000	-		-	Restricted Stock Unit
Richard M. Mitrano	VP Finance & Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	91,000	91,000	-		-	Restricted Stock Unit
Quentin McCubbin	Chief Manufacturing Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	26 Jan 2023	105,000	105,000	-		-	Restricted Stock Unit
Joel S. Marcus	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Joel S. Marcus	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Joel S. Marcus	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Joel S. Marcus	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Robert S. Langer	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Robert S. Langer	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Robert S. Langer	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Robert S. Langer	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Timothy J. Barberich	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Timothy J. Barberich	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Timothy J. Barberich	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Timothy J. Barberich	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Cynthia L. Feldmann	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Cynthia L. Feldmann	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Cynthia L. Feldmann	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	29,693	0	-		-	Stock Option
Cynthia L. Feldmann	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	29,693	29,693	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	178,937	0	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	75,000	75,000	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	75,000	0	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	57,500	57,500	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	57,500	0	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	178,937	178,937	-		-	Stock Option
Wendy S. Arnold	Chief People Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	130,000	0	-		-	Stock Option
Wendy S. Arnold	Chief People Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	75,000	75,000	-		-	Stock Option
Wendy S. Arnold	Chief People Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	75,000	0	-		-	Stock Option
Wendy S. Arnold	Chief People Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	130,000	130,000	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	714,413	714,413	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	200,000	200,000	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	200,000	0	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	242,500	0	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	242,500	242,500	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	714,413	0	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	146,826	146,826	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	70,000	0	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	70,000	70,000	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	57,500	0	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	57,500	57,500	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	146,826	0	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	17,816	17,816	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	11,550	0	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	11,550	11,550	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	18,000	0	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	18,000	18,000	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	17,816	0	-		-	Stock Option
Michael Huang	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Michael Huang	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	14,846	14,846	-		-	Stock Option
Michael Huang	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Michael Huang	Director	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	14,846	0	-		-	Stock Option
Quentin McCubbin	Chief Manufacturing Officer	Sale or transfer of securities back to the company at price $ 0.00 per share.	17 Aug 2022	90,000	0	-		-	Stock Option
Quentin McCubbin	Chief Manufacturing Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Aug 2022	90,000	90,000	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Sale of securities on an exchange or to another person at price $ 1.52 per share.	05 Jul 2022	4,421	26,343 (0%)	0%	1.5	6,720	Common Stock
Carl P. LeBel	Chief Development Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	15,000	0	-		-	Restricted Stock Unit
Carl P. LeBel	Chief Development Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	15,000	30,764 (0%)	0%		-	Common Stock
Wendy S. Arnold	Chief People Officer	Sale of securities on an exchange or to another person at price $ 1.52 per share.	05 Jul 2022	5,638	21,186 (0%)	0%	1.5	8,570	Common Stock
Wendy S. Arnold	Chief People Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	15,000	26,824 (0%)	0%		-	Common Stock
Wendy S. Arnold	Chief People Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	15,000	0	-		-	Restricted Stock Unit
Christopher R. Loose	Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	15,000	54,465 (0%)	0%		-	Common Stock
Christopher R. Loose	Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	15,000	0	-		-	Restricted Stock Unit
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 1.53 per share.	05 Jul 2022	4,415	50,050 (0%)	0%	1.5	6,755	Common Stock
Richard M. Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	7,500	0	-		-	Restricted Stock Unit
Richard M. Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	7,500	33,179 (0%)	0%		-	Common Stock
Richard M. Mitrano	VP Finance & Operations	Sale of securities on an exchange or to another person at price $ 1.54 per share.	05 Jul 2022	2,184	30,995 (0%)	0%	1.5	3,363	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	17,500	44,909 (0%)	0%		-	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Sale of securities on an exchange or to another person at price $ 1.52 per share.	05 Jul 2022	6,569	38,340 (0%)	0%	1.5	9,985	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Jul 2022	17,500	0	-		-	Restricted Stock Unit
Joel S. Marcus	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Jun 2022	14,846	14,846	-		-	Stock Option
Marc A. Cohen	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Jun 2022	14,846	14,846	-		-	Stock Option
Robert S. Langer	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Jun 2022	14,846	14,846	-		-	Stock Option
Timothy J. Barberich	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Jun 2022	14,846	14,846	-		-	Stock Option
Cynthia L. Feldmann	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Jun 2022	14,846	14,846	-		-	Stock Option
Michael Huang	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 Jun 2022	14,846	14,846	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Sale of securities on an exchange or to another person at price $ 3.53 per share.	18 Feb 2022	1,069	11,126 (0%)	0%	3.5	3,773	Common Stock
Carl P. LeBel	Chief Development Officer	Sale of securities on an exchange or to another person at price $ 3.87 per share.	18 Feb 2022	974	12,195 (0%)	0%	3.9	3,772	Common Stock
Peter P. Pfreundschuh	Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 3.53 per share.	18 Feb 2022	1,542	8,927 (0%)	0%	3.5	5,442	Common Stock
Peter P. Pfreundschuh	Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 3.88 per share.	18 Feb 2022	1,404	10,469 (0%)	0%	3.9	5,443	Common Stock
Wendy S. Arnold	Chief People Officer	Sale of securities on an exchange or to another person at price $ 3.53 per share.	18 Feb 2022	1,326	11,824 (0%)	0%	3.5	4,683	Common Stock
Wendy S. Arnold	Chief People Officer	Sale of securities on an exchange or to another person at price $ 3.87 per share.	18 Feb 2022	1,209	13,150 (0%)	0%	3.9	4,684	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 3.87 per share.	18 Feb 2022	974	35,896 (0%)	0%	3.9	3,772	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 3.53 per share.	18 Feb 2022	1,069	34,827 (0%)	0%	3.5	3,774	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Sale of securities on an exchange or to another person at price $ 3.87 per share.	18 Feb 2022	1,411	24,355 (0%)	0%	3.9	5,463	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Sale of securities on an exchange or to another person at price $ 3.53 per share.	18 Feb 2022	1,584	22,771 (0%)	0%	3.5	5,598	Common Stock
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Feb 2022	300,000	300,000	-		-	Restricted Stock Unit
Carl P. LeBel	Chief Development Officer	Sale of securities on an exchange or to another person at price $ 4.43 per share.	16 Feb 2022	831	14,070 (0%)	0%	4.4	3,680	Common Stock
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2022	150,000	150,000	-		-	Restricted Stock Unit
Carl P. LeBel	Chief Development Officer	Sale of securities on an exchange or to another person at price $ 4.19 per share.	16 Feb 2022	901	13,169 (0%)	0%	4.2	3,774	Common Stock
Peter P. Pfreundschuh	Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2022	150,000	150,000	-		-	Restricted Stock Unit
Peter P. Pfreundschuh	Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 4.20 per share.	16 Feb 2022	1,296	11,873 (0%)	0%	4.2	5,443	Common Stock
Peter P. Pfreundschuh	Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 4.43 per share.	16 Feb 2022	1,229	13,169 (0%)	0%	4.4	5,443	Common Stock
Wendy S. Arnold	Chief People Officer	Sale of securities on an exchange or to another person at price $ 4.43 per share.	16 Feb 2022	1,057	15,477 (0%)	0%	4.4	4,681	Common Stock
Wendy S. Arnold	Chief People Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2022	150,000	150,000	-		-	Restricted Stock Unit
Wendy S. Arnold	Chief People Officer	Sale of securities on an exchange or to another person at price $ 4.19 per share.	16 Feb 2022	1,118	14,359 (0%)	0%	4.2	4,688	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 4.43 per share.	16 Feb 2022	851	37,770 (0%)	0%	4.4	3,769	Common Stock
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2022	150,000	150,000	-		-	Restricted Stock Unit
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 4.19 per share.	16 Feb 2022	900	36,870 (0%)	0%	4.2	3,774	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Sale of securities on an exchange or to another person at price $ 4.43 per share.	16 Feb 2022	1,233	27,069 (0%)	0%	4.4	5,461	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2022	150,000	150,000	-		-	Restricted Stock Unit
Quentin McCubbin	Chief Manufacturing Officer	Sale of securities on an exchange or to another person at price $ 4.20 per share.	16 Feb 2022	1,303	25,766 (0%)	0%	4.2	5,467	Common Stock
Carl P. LeBel	Chief Development Officer	Sale of securities on an exchange or to another person at price $ 4.33 per share.	14 Feb 2022	844	14,901 (0%)	0%	4.3	3,655	Common Stock
Carl P. LeBel	Chief Development Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	15,000	-		-	Restricted Stock Unit
Carl P. LeBel	Chief Development Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	15,745 (0%)	0%		-	Common Stock
Peter P. Pfreundschuh	Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 4.33 per share.	14 Feb 2022	1,347	14,398 (0%)	0%	4.3	5,834	Common Stock
Peter P. Pfreundschuh	Chief Financial Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	15,745 (0%)	0%		-	Common Stock
Peter P. Pfreundschuh	Chief Financial Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	15,000	-		-	Restricted Stock Unit
Wendy S. Arnold	Chief People Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	17,702 (0%)	0%		-	Common Stock
Wendy S. Arnold	Chief People Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	15,000	-		-	Restricted Stock Unit
Wendy S. Arnold	Chief People Officer	Sale of securities on an exchange or to another person at price $ 4.33 per share.	14 Feb 2022	1,168	16,534 (0%)	0%	4.3	5,059	Common Stock
Christopher R. Loose	Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	39,484 (0%)	0%		-	Common Stock
Christopher R. Loose	Chief Scientific Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	15,000	15,000	-		-	Restricted Stock Unit
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 4.33 per share.	14 Feb 2022	863	38,621 (0%)	0%	4.3	3,738	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	17,500	17,500	-		-	Restricted Stock Unit
Quentin McCubbin	Chief Manufacturing Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Feb 2022	17,500	29,563 (0%)	0%		-	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Sale of securities on an exchange or to another person at price $ 4.33 per share.	14 Feb 2022	1,261	28,302 (0%)	0%	4.3	5,461	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	18 Jan 2022	6,905	470,111 (1%)	0%	0.6	4,212	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	18 Jan 2022	6,905	0	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Nov 2021	6,905	13,810	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	02 Nov 2021	6,905	456,301 (1%)	0%	0.6	4,212	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Oct 2021	6,905	20,715	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	05 Oct 2021	6,905	449,396 (1%)	0%	0.6	4,212	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	03 Sep 2021	6,905	442,491 (1%)	0%	0.6	4,212	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Sep 2021	6,905	27,620	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Aug 2021	6,905	34,525	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	03 Aug 2021	6,905	435,586 (1%)	0%	0.6	4,212	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Jul 2021	6,905	41,430	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	01 Jul 2021	6,905	428,681 (1%)	0%	0.6	4,212	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	21 Jun 2021	113,690	421,776 (1%)	0%	0.6	69,351	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	21 Jun 2021	113,690	48,335	-		-	Stock Option
Joel S. Marcus	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jun 2021	14,846	14,846	-		-	Stock Option
Marc A. Cohen	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jun 2021	14,846	14,846	-		-	Stock Option
Robert S. Langer	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jun 2021	14,846	14,846	-		-	Stock Option
Timothy J. Barberich	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jun 2021	14,846	14,846	-		-	Stock Option
Cynthia L. Feldmann	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jun 2021	14,846	14,846	-		-	Stock Option
Michael Huang	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	17 Jun 2021	14,846	14,846	-		-	Stock Option
Quentin McCubbin	Chief Manufacturing Officer	Purchase of securities on an exchange or from another person at price $ 8.85 per share.	17 May 2021	10,000	10,000 (0%)	0%	8.9	88,500	Common Stock
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Apr 2021	30,000	30,000	-		-	Restricted Stock Unit
Peter P. Pfreundschuh	Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Apr 2021	30,000	30,000	-		-	Restricted Stock Unit
Wendy S. Arnold	Chief People Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Apr 2021	30,000	30,000	-		-	Restricted Stock Unit
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Apr 2021	30,000	30,000	-		-	Restricted Stock Unit
Michael D. Bookman	General Counsel and Secretary	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Apr 2021	30,000	30,000	-		-	Restricted Stock Unit
Quentin McCubbin	Chief Manufacturing Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	20 Apr 2021	35,000	35,000	-		-	Restricted Stock Unit
Joel S. Marcus	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Mar 2021	37,116	0	-		-	Stock Option
Joel S. Marcus	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.37 per share.	25 Mar 2021	37,116	307,116 (0%)	0%	3.4	125,081	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 47.84 per share.	01 Mar 2021	1,079	316,423 (1%)	0%	47.8	51,618	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Mar 2021	9,416	162,025	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 52.11 per share.	01 Mar 2021	192	308,086 (1%)	0%	52.1	10,005	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 51.76 per share.	01 Mar 2021	4,202	308,278 (1%)	0%	51.8	217,492	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	01 Mar 2021	2,688	312,480 (1%)	0%	50.0	134,410	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 48.85 per share.	01 Mar 2021	1,255	315,168 (1%)	0%	48.9	61,311	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	01 Mar 2021	9,416	317,502 (1%)	0%	0.6	5,744	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 52.50 per share.	08 Feb 2021	5,518	319,122 (1%)	0%	52.5	289,695	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Feb 2021	16,554	171,441	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 57.50 per share.	08 Feb 2021	5,518	308,086 (1%)	0%	57.5	317,285	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 55.00 per share.	08 Feb 2021	5,518	313,604 (1%)	0%	55	303,490	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	08 Feb 2021	16,554	324,640 (1%)	0%	0.6	10,098	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 47.50 per share.	03 Feb 2021	5,518	313,604 (1%)	0%	47.5	262,105	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	03 Feb 2021	11,036	319,122 (1%)	0%	0.6	6,732	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	03 Feb 2021	5,518	308,086 (1%)	0%	50	275,900	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Feb 2021	11,036	187,995	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 45.76 per share.	02 Feb 2021	3,800	309,804 (1%)	0%	45.8	173,882	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 47.33 per share.	02 Feb 2021	9	308,086 (1%)	0%	47.3	426	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 46.84 per share.	02 Feb 2021	1,709	308,095 (1%)	0%	46.8	80,051	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	02 Feb 2021	5,518	313,604 (1%)	0%	0.6	3,366	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Feb 2021	5,518	199,031	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 45.02 per share.	02 Feb 2021	8,000	23,782 (0%)	0%	45.0	360,196	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 47.19 per share.	02 Feb 2021	2,000	21,782 (0%)	0%	47.2	94,380	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 44.58 per share.	01 Feb 2021	2,702	308,086 (1%)	0%	44.6	120,459	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Feb 2021	33,102	204,549	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 43.71 per share.	01 Feb 2021	8,900	310,788 (1%)	0%	43.7	389,056	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 42.85 per share.	01 Feb 2021	18,600	319,688 (1%)	0%	42.9	797,099	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 41.29 per share.	01 Feb 2021	2,900	338,288 (1%)	0%	41.3	119,755	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	01 Feb 2021	33,102	341,188 (1%)	0%	0.6	20,192	Common Stock
Quentin McCubbin	Chief Manufacturing Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 Jan 2021	90,000	90,000	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	27 Jan 2021	9,196	317,282 (1%)	0%	0.6	5,610	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Jan 2021	9,196	237,651	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 42.50 per share.	27 Jan 2021	9,196	308,086 (1%)	0%	42.5	390,830	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 42.50 per share.	27 Jan 2021	8,000	31,782 (0%)	0%	42.5	340,000	Common Stock
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jan 2021	75,000	75,000	-		-	Stock Option
Peter P. Pfreundschuh	Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jan 2021	10,000	10,000	-		-	Stock Option
Wendy S. Arnold	Chief People Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jan 2021	75,000	75,000	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jan 2021	200,000	200,000	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	15 Jan 2021	70,000	70,000	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 37.45 per share.	06 Jan 2021	10,707	324,065 (1%)	0%	37.4	400,977	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	06 Jan 2021	27,586	335,672 (1%)	0%	0.6	16,827	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 36.13 per share.	06 Jan 2021	900	334,772 (1%)	0%	36.1	32,517	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	06 Jan 2021	27,586	246,847	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 40.00 per share.	06 Jan 2021	9,496	308,086 (1%)	0%	40.0	379,810	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 39.37 per share.	06 Jan 2021	2,319	317,582 (1%)	0%	39.4	91,299	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 38.26 per share.	06 Jan 2021	4,164	319,901 (1%)	0%	38.3	159,315	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 33.81 per share.	04 Jan 2021	11,763	308,186 (1%)	0%	33.8	397,732	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Jan 2021	14,477	274,433	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Jan 2021	3,913	0	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 35.46 per share.	04 Jan 2021	100	308,086 (1%)	0%	35.5	3,546	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	04 Jan 2021	14,477	342,190 (1%)	0%	0.6	8,831	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 32.89 per share.	04 Jan 2021	22,241	319,949 (1%)	0%	32.9	731,462	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	04 Jan 2021	3,913	327,713 (1%)	0%	0.6	2,387	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 33.92 per share.	18 Dec 2020	2,310	317,390 (1%)	0%	33.9	78,359	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 34.27 per share.	18 Dec 2020	10,000	270,000 (0%)	0%	34.3	342,738	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 33.82 per share.	18 Dec 2020	1,120	280,000 (0%)	0%	33.8	37,879	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 32.97 per share.	18 Dec 2020	7,441	281,120 (0%)	0%	33.0	245,339	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 32.09 per share.	18 Dec 2020	1,439	288,561 (0%)	0%	32.1	46,178	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 30.35 per share.	18 Dec 2020	10,000	290,000 (0%)	0%	30.4	303,521	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 38.27 per share.	18 Dec 2020	8,412	300,000 (0%)	0%	38.3	321,910	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 37.21 per share.	18 Dec 2020	4,300	308,412 (1%)	0%	37.2	159,991	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 36.03 per share.	18 Dec 2020	2,864	312,712 (1%)	0%	36.0	103,191	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 34.90 per share.	18 Dec 2020	1,814	315,576 (1%)	0%	34.9	63,306	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 42.64 per share.	17 Dec 2020	1,120	323,800 (1%)	0%	42.6	47,755	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	17 Dec 2020	1,120	288,910	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	17 Dec 2020	1,120	324,920 (1%)	0%	0.6	683	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 42.50 per share.	17 Dec 2020	2,000	39,782 (0%)	0%	42.5	85,001	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 40.00 per share.	17 Dec 2020	6,000	41,782 (0%)	0%	40	240,000	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 35.12 per share.	14 Dec 2020	13,514	323,800 (1%)	0%	35.1	474,612	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Dec 2020	13,514	290,030	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Dec 2020	7,103	303,544	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Dec 2020	6,411	3,913	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Dec 2020	13,514	10,324	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 40.00 per share.	14 Dec 2020	13,514	323,800 (1%)	0%	40	540,560	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	14 Dec 2020	13,514	337,314 (1%)	0%	0.6	8,244	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 38.83 per share.	14 Dec 2020	4,500	323,800 (1%)	0%	38.8	174,735	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 38.18 per share.	14 Dec 2020	9,014	328,300 (1%)	0%	38.2	344,155	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	14 Dec 2020	7,103	337,314 (1%)	0%	0.6	4,333	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	14 Dec 2020	6,411	330,211 (1%)	0%	0.6	3,911	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	14 Dec 2020	13,514	337,314 (1%)	0%	0.6	8,244	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 37.28 per share.	14 Dec 2020	8,000	55,782 (0%)	0%	37.3	298,240	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 40.00 per share.	14 Dec 2020	4,000	47,782 (0%)	0%	40	160,000	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 37.87 per share.	14 Dec 2020	4,000	51,782 (0%)	0%	37.9	151,480	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 35.00 per share.	14 Dec 2020	8,000	63,782 (0%)	0%	35	280,000	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Dec 2020	13,514	23,838	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 32.93 per share.	09 Dec 2020	13,514	323,800 (1%)	0%	32.9	444,984	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	09 Dec 2020	13,514	337,314 (1%)	0%	0.6	8,244	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 31.52 per share.	07 Dec 2020	4,798	323,800 (1%)	0%	31.5	151,233	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 30.96 per share.	07 Dec 2020	4,050	328,598 (1%)	0%	31.0	125,388	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	07 Dec 2020	8,848	332,648 (1%)	0%	0.6	5,397	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 30.02 per share.	07 Dec 2020	4,666	323,800 (1%)	0%	30.0	140,065	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	07 Dec 2020	4,666	328,466 (1%)	0%	0.6	2,846	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Dec 2020	8,848	37,352	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Dec 2020	4,666	46,200	-		-	Stock Option
Peter P. Pfreundschuh	Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Dec 2020	230,000	230,000	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 28.65 per share.	01 Dec 2020	600	323,800 (1%)	0%	28.7	17,190	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 27.90 per share.	01 Dec 2020	15,114	324,400 (1%)	0%	27.9	421,681	Common Stock
Robert S. Langer	Director	Gift of securities by or to the insider at price $ 0.00 per share.	17 Nov 2020	56,912	214,326 (0%)	0%		0	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 24.00 per share.	05 Nov 2020	8,000	71,782 (0%)	0%	24	192,000	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 23.00 per share.	05 Nov 2020	8,000	79,782 (0%)	0%	23	184,000	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 20.68 per share.	02 Nov 2020	12,965	342,263 (1%)	0%	20.7	268,116	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 21.41 per share.	02 Nov 2020	2,749	339,514 (1%)	0%	21.4	58,856	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 22.00 per share.	13 Oct 2020	8,000	87,782 (0%)	0%	22	176,000	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 20.00 per share.	06 Oct 2020	8,000	103,782 (0%)	0%	20.0	160,010	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 21.12 per share.	06 Oct 2020	8,000	95,782 (0%)	0%	21.1	168,960	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 19.46 per share.	06 Oct 2020	8,000	111,782 (0%)	0%	19.5	155,680	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 18.87 per share.	01 Oct 2020	10,838	360,106 (1%)	0%	18.9	204,513	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 19.71 per share.	01 Oct 2020	4,878	355,228 (1%)	0%	19.7	96,145	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 18.92 per share.	01 Oct 2020	8,000	127,782 (0%)	0%	18.9	151,360	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 18.84 per share.	01 Oct 2020	8,000	135,782 (0%)	0%	18.8	150,720	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 18.35 per share.	01 Oct 2020	8,000	119,782 (0%)	0%	18.4	146,800	Common Stock
Cynthia L. Feldmann	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 Sep 2020	29,693	29,693	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 22.42 per share.	23 Sep 2020	24	143,782 (0%)	0%	22.4	538	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 20.51 per share.	23 Sep 2020	1,870	146,412 (0%)	0%	20.5	38,358	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 21.57 per share.	23 Sep 2020	2,606	143,806 (0%)	0%	21.6	56,201	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 19.26 per share.	09 Sep 2020	776	148,282 (0%)	0%	19.3	14,944	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 18.91 per share.	09 Sep 2020	3,724	149,058 (0%)	0%	18.9	70,425	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 19.05 per share.	01 Sep 2020	3,586	370,944 (1%)	0%	19.1	68,318	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 18.40 per share.	01 Sep 2020	12,128	374,530 (1%)	0%	18.4	223,155	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 22.97 per share.	19 Aug 2020	4,500	152,782 (0%)	0%	23.0	103,350	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 21.21 per share.	05 Aug 2020	4,442	157,340 (0%)	0%	21.2	94,193	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 21.91 per share.	05 Aug 2020	58	157,282 (0%)	0%	21.9	1,271	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 21.63 per share.	03 Aug 2020	15,714	386,658 (1%)	0%	21.6	339,829	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 21.51 per share.	22 Jul 2020	4,500	161,782 (0%)	0%	21.5	96,791	Common Stock
Joel S. Marcus	Director	Grant, award, or other acquisition of securities at price $ 18.00 per share.	20 Jul 2020	55,555	1,011,730 (3%)	0%	18	999,990	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 22.97 per share.	08 Jul 2020	779	166,282 (0%)	0%	23.0	17,891	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 22.18 per share.	08 Jul 2020	3,721	167,061 (0%)	0%	22.2	82,548	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 22.45 per share.	01 Jul 2020	15,714	402,372 (1%)	0%	22.5	352,833	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 22.80 per share.	24 Jun 2020	4,500	170,782 (0%)	0%	22.8	102,587	Common Stock
Joel S. Marcus	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 Jun 2020	14,846	14,846	-		-	Stock Option
Marc A. Cohen	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 Jun 2020	14,846	14,846	-		-	Stock Option
Robert S. Langer	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 Jun 2020	14,846	14,846	-		-	Stock Option
Timothy J. Barberich	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 Jun 2020	14,846	14,846	-		-	Stock Option
Michael Huang	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	11 Jun 2020	14,846	14,846	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 19.96 per share.	10 Jun 2020	4,500	175,282 (0%)	0%	20.0	89,829	Common Stock
Richard Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	03 Jun 2020	2,552	15,015 (0%)	0%	0.6	1,557	Common Stock
Richard Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Jun 2020	2,552	1,191	-		-	Stock Option
Richard Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	03 Jun 2020	929	124	-		-	Stock Option
Richard Mitrano	VP Finance & Operations	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.07 per share.	03 Jun 2020	929	12,463 (0%)	0%	0.1	65	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 18.57 per share.	02 Jun 2020	3,839	418,086 (1%)	0%	18.6	71,276	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 17.91 per share.	01 Jun 2020	11,875	421,925 (1%)	0%	17.9	212,654	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 18.81 per share.	21 May 2020	5,000	319,700 (1%)	0%	18.8	94,053	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 18.82 per share.	20 May 2020	2,668	189,114 (0%)	0%	18.8	50,202	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 19.33 per share.	20 May 2020	1,832	187,282 (0%)	0%	19.3	35,408	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 18.40 per share.	18 May 2020	7,809	329,700 (1%)	0%	18.4	143,671	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 18.76 per share.	18 May 2020	5,000	324,700 (1%)	0%	18.8	93,796	Common Stock
Joel S. Marcus	Director	Sale of securities on an exchange or to another person at price $ 19.15 per share.	18 May 2020	15,000	337,509 (1%)	0%	19.1	287,189	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 18.18 per share.	08 May 2020	10,478	433,800 (1%)	0%	18.2	190,494	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 16.68 per share.	06 May 2020	554	191,782 (0%)	0%	16.7	9,240	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 16.23 per share.	06 May 2020	3,946	192,336 (0%)	0%	16.2	64,028	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 16.19 per share.	05 May 2020	5,239	444,278 (1%)	0%	16.2	84,835	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 15.28 per share.	01 May 2020	5,236	449,517 (1%)	0%	15.3	79,997	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 16.35 per share.	24 Apr 2020	729	454,753 (1%)	0%	16.3	11,919	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 16.08 per share.	23 Apr 2020	1,410	455,482 (1%)	0%	16.1	22,674	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 14.84 per share.	22 Apr 2020	4,500	196,282 (0%)	0%	14.8	66,794	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 16.00 per share.	17 Apr 2020	3,100	456,892 (1%)	0%	16	49,600	Common Stock
David L. Lucchino	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 15.13 per share.	15 Apr 2020	5,236	459,992 (1%)	0%	15.1	79,234	Common Stock
Christopher R. Loose	Chief Scientific Officer	Sale of securities on an exchange or to another person at price $ 14.99 per share.	08 Apr 2020	4,500	200,782 (0%)	0%	15.0	67,469	Common Stock
Carl LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Feb 2020	57,500	57,500	-		-	Stock Option
Wendy Arnold	Chief People Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Feb 2020	130,000	130,000	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Feb 2020	242,500	242,500	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Feb 2020	57,500	57,500	-		-	Stock Option
Richard Mitrano	VP Finance & Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	12 Feb 2020	18,000	18,000	-		-	Stock Option
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	30 Jan 2020	16,691	542,437 (1%)	0%	0.6	10,182	Common Stock
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2020	20,778	0	-		-	Stock Option
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2020	20,778	0	-		-	Stock Option
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2020	21,827	32,918	-		-	Stock Option
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2020	16,691	50,072	-		-	Stock Option
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Jan 2020	8,042	12,063	-		-	Stock Option
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.37 per share.	30 Jan 2020	20,778	605,820 (1%)	0%	3.4	70,022	Common Stock
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.37 per share.	30 Jan 2020	20,778	585,042 (1%)	0%	3.4	70,022	Common Stock
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.37 per share.	30 Jan 2020	21,827	564,264 (1%)	0%	3.4	73,557	Common Stock
Marc A. Cohen	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	30 Jan 2020	8,042	525,746 (1%)	0%	0.6	4,906	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Dec 2019	20,787	310,647	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	30 Dec 2019	36,590	444,441 (1%)	0%	0.6	22,320	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.61 per share.	30 Dec 2019	20,787	465,228 (1%)	0%	0.6	12,680	Common Stock
David L. Lucchino	Director, President and CEO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Dec 2019	36,590	50,866	-		-	Stock Option
Marc A. Cohen	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Dec 2019	20,778	20,778	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Dec 2019	23,555	23,555	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Dec 2019	96,361	96,361	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Dec 2019	64,241	64,241	-		-	Stock Option
Joel S. Marcus	Director		07 Oct 2019	4,161,974	0	-		-	Series A Preferred Stock
Joel S. Marcus	Director		07 Oct 2019	1,534,513	0	-		-	Series A Preferred Stock
Joel S. Marcus	Director		07 Oct 2019	839,816	0	-		-	Series B Preferred Stock
Joel S. Marcus	Director		07 Oct 2019	617,916	956,175 (3%)	2%		-	Common Stock
Joel S. Marcus	Director		07 Oct 2019	352,509	352,509 (1%)	1%		-	Common Stock
Joel S. Marcus	Director		07 Oct 2019	2,278,345	0	-		-	Series B Preferred Stock
Marc A. Cohen	Director		07 Oct 2019	445,229	517,704 (1%)	1%		-	Common Stock
Marc A. Cohen	Director		07 Oct 2019	163,388	0	-		-	Series C Preferred Stock
Marc A. Cohen	Director		07 Oct 2019	543,219	0	-		-	Series B Preferred Stock
Marc A. Cohen	Director		07 Oct 2019	2,292,235	0	-		-	Series A Preferred Stock
Marc A. Cohen	Director	Purchase of securities on an exchange or from another person at price $ 14.00 per share.	07 Oct 2019	17,857	17,857 (0%)	0%	14	249,998	Common Stock
Timothy J. Barberich	Director		07 Oct 2019	80,650	80,650 (0%)	0%		-	Common Stock
Timothy J. Barberich	Director		07 Oct 2019	543,219	0	-		-	Series B Preferred Stock
Timothy J. Barberich	Director		07 Oct 2019	506,278	0	-		-	Series A Preferred Stock
Timothy J. Barberich	Director		07 Oct 2019	84,622	102,089 (0%)	0%		-	Common Stock
Timothy J. Barberich	Director		07 Oct 2019	63,698	0	-		-	Series C Preferred Stock
David L. Lucchino	Director, President and CEO		07 Oct 2019	27,161	0	-		-	Series B Preferred Stock
David L. Lucchino	Director, President and CEO		07 Oct 2019	43,989	0	-		-	Series A Preferred Stock
David L. Lucchino	Director, President and CEO		07 Oct 2019	10,563	407,851 (1%)	0%		-	Common Stock
Christopher R. Loose	Chief Scientific Officer		07 Oct 2019	45,182	0	-		-	Series A Preferred Stock
Christopher R. Loose	Chief Scientific Officer		07 Oct 2019	6,708	205,282 (0%)	0%		-	Common Stock
Richard M. Mitrano	VP Finance & Operations		07 Oct 2019	4,032	15,566 (0%)	0%		-	Common Stock
Richard M. Mitrano	VP Finance & Operations	Purchase of securities on an exchange or from another person at price $ 14.00 per share.	07 Oct 2019	107	15,673 (0%)	0%	14	1,498	Common Stock
Richard M. Mitrano	VP Finance & Operations		07 Oct 2019	27,160	0	-		-	Series B Preferred Stock
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	23,555	23,555	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	101,930	101,930	-		-	Stock Option
Carl P. LeBel	Chief Development Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	178,937	178,937	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	714,413	714,413	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	444,371	444,371	-		-	Stock Option
David L. Lucchino	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	96,361	96,361	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	146,826	146,826	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	64,241	64,241	-		-	Stock Option
Christopher R. Loose	Chief Scientific Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	360,606	360,606	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	33,305	33,305	-		-	Stock Option
Richard M. Mitrano	VP Finance & Operations	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Oct 2019	17,816	17,816	-		-	Stock Option

*All Values are in $ Million

Client Category: Promoter/ KMP/ Director / Immediate Relatives / Employee / etc
Security Type: Share/ Warrants / Convertible Debentures

Data as reported to USA Exchanges

View All The Insider Trades disclosures

Insider Trading disclosures for Frequency Therapeutics Inc

The latest disclosure was made by David L. Lucchino in Frequency Therapeutics Inc where a trade of 3,057 Common Stock done at an average price of $0.5 was reported to US exchanges on Aug. 18, 2023.

Screeners based on Insider Trading and SAST parameters