25,423 XNAS Volume
XNAS 03 Apr, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Michael M. Rowe | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.52 per share. | 28 Aug 2024 | 27,071 | 109,998 (0%) | 0% | 0.5 | 14,077 | Common Stock, par value $0.0001 |
| Michael M. Rowe | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.57 per share. | 26 Aug 2024 | 50,000 | 82,927 (0%) | 0% | 0.6 | 28,500 | Common Stock, par value $0.0001 |
| Stuart M. Grant | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 02 Jul 2024 | 3,264,931 | 3,942,361 | - | - | Warrants to purchase common stock | |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.66 per share. | 02 Jul 2024 | 1,515,151 | 10,914,153 (63%) | 8% | 0.7 | 1,000,000 | Common stock, par value $0.0001 |
| Michael S. Geltzeiler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 85,106 | 85,106 | - | - | Stock Option (right to buy) | |
| Michael S. Geltzeiler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 61,481 | 81,295 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 85,106 | 85,106 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 61,481 | 156,266 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ellen R. Strahlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 85,106 | 85,106 | - | - | Stock Option (right to buy) | |
| Ellen R. Strahlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 61,481 | 136,594 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Tsontcho Ianchulev | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 85,106 | 85,106 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 61,481 | 409,933 (2%) | 0% | 0 | Common Stock, par value $.0001 | |
| Rachel Jacobson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 85,106 | 85,106 | - | - | Stock Option (right to buy) | |
| Rachel Jacobson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 61,481 | 104,233 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ram Palanki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 85,106 | 85,106 | - | - | Stock Option (right to buy) | |
| Ram Palanki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2024 | 61,481 | 98,909 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.98 per share. | 28 Mar 2024 | 100,000 | 5,430,715 (31%) | 0% | 1.0 | 98,000 | Common stock, par value $0.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.23 per share. | 19 Mar 2024 | 50,000 | 5,330,715 (31%) | 0% | 1.2 | 61,500 | Common stock, par value $0.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.58 per share. | 08 Mar 2024 | 10,717 | 5,280,715 (30%) | 0% | 1.6 | 16,911 | Common stock, par value $0.0001 |
| Michael M. Rowe | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| P. John Gandolfo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 60,000 | 60,000 | - | - | Stock Option (right to buy) | |
| Bren Kern | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| M. Rowe Michael | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 1.36 per share. | 04 Dec 2023 | 4,890 | 32,927 (0%) | 0% | 1.4 | 6,650 | Common Stock, par value $.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.87 per share. | 16 Aug 2023 | 30,000 | 5,269,998 (30%) | 0% | 1.9 | 56,100 | Common Stock, par value $0.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.91 per share. | 16 Aug 2023 | 45,000 | 5,239,998 (30%) | 0% | 1.9 | 85,815 | Common stock, par value $0.0001 |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 24,691 | 24,691 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 17,241 | 94,785 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ellen R. Strahlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 24,691 | 24,691 | - | - | Stock Option (right to buy) | |
| Ellen R. Strahlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 17,241 | 70,293 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Tsontcho Ianchulev | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 24,691 | 24,691 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 17,241 | 348,452 (2%) | 0% | 0 | Common Stock, par value $.0001 | |
| Rachel Jacobson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 24,691 | 24,691 | - | - | Stock Option (right to buy) | |
| Rachel Jacobson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 17,241 | 42,752 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ram Palanki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 24,691 | 24,691 | - | - | Stock Option (right to buy) | |
| Ram Palanki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2023 | 17,241 | 37,428 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| John P. Gandolfo | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 2.79 per share. | 31 May 2023 | 2,000 | 8,000 (0%) | 0% | 2.8 | 5,580 | Common Stock, par value $.0001 |
| Charles E. Mather | Director | Purchase of securities on an exchange or from another person at price $ 2.49 per share. | 26 May 2023 | 3,000 | 77,544 (0%) | 0% | 2.5 | 7,470 | Common Stock, par value $.0001 |
| Bren Kern | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.73 per share. | 26 May 2023 | 2,500 | 2,500 (0%) | 0% | 2.7 | 6,825 | Common Stock, par value $.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.65 per share. | 25 May 2023 | 88,247 | 5,194,998 (30%) | 0% | 2.7 | 233,855 | Common stock, par value $0.0001 |
| Ellen R. Strahlman | Director | Purchase of securities on an exchange or from another person at price $ 3.10 per share. | 23 May 2023 | 10,000 | 53,052 (0%) | 0% | 3.1 | 30,976 | Common Stock, par value $.0001 |
| Charles E. Mather | Director | Purchase of securities on an exchange or from another person at price $ 3.39 per share. | 15 May 2023 | 4,000 | 74,544 (0%) | 0% | 3.4 | 13,560 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director | Sale of securities on an exchange or to another person at price $ 5.50 per share. | 01 May 2023 | 90,000 | 331,211 (1%) | 0% | 5.5 | 495,000 | Common Stock, par value $.0001 |
| Michael M. Rowe | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.72 per share. | 01 May 2023 | 10,000 | 25,500 (0%) | 0% | 2.7 | 27,200 | Common Stock, par value $.0001 |
| Michael M. Rowe | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 10,000 | 131,622 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director | Sale of securities on an exchange or to another person at price $ 5.00 per share. | 27 Apr 2023 | 60,000 | 421,211 (2%) | 0% | 5 | 300,000 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director | Sale of securities on an exchange or to another person at price $ 4.50 per share. | 14 Apr 2023 | 40,000 | 481,211 (2%) | 0% | 4.5 | 180,000 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director | Sale of securities on an exchange or to another person at price $ 4.00 per share. | 11 Apr 2023 | 40,000 | 521,211 (3%) | 0% | 4 | 160,000 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director | Sale of securities on an exchange or to another person at price $ 3.50 per share. | 31 Mar 2023 | 40,000 | 561,211 (3%) | 0% | 3.5 | 140,000 | Common Stock, par value $.0001 |
| John P. Gandolfo | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 68,235 | 68,235 | - | - | Stock Option (right to buy) | |
| Bren Kern | CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 120,000 | 120,000 | - | - | Stock Option (right to buy) | |
| Michael M. Rowe | Director, CHIEF EXECUTIVE OFFICER | Purchase of securities on an exchange or from another person at price $ 1.54 per share. | 30 Dec 2022 | 10,000 | 15,500 (0%) | 0% | 1.5 | 15,400 | Common Stock, par value $.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 30 Dec 2022 | 21,753 | 5,106,751 (29%) | 0% | 1.5 | 32,630 | Common stock, par value $0.0001 |
| Ellen R. Strahlman | Director | Purchase of securities on an exchange or from another person at price $ 1.62 per share. | 29 Aug 2022 | 6,686 | 43,052 (0%) | 0% | 1.6 | 10,805 | Common Stock, par value $.0001 |
| Ellen R. Strahlman | Director | Purchase of securities on an exchange or from another person at price $ 1.60 per share. | 29 Aug 2022 | 6,744 | 36,366 (0%) | 0% | 1.6 | 10,803 | Common Stock, par value $.0001 |
| Ellen R. Strahlman | Director | Purchase of securities on an exchange or from another person at price $ 1.62 per share. | 29 Aug 2022 | 7,931 | 29,622 (0%) | 0% | 1.6 | 12,838 | Common Stock, par value $.0001 |
| Ellen R. Strahlman | Director | Purchase of securities on an exchange or from another person at price $ 1.59 per share. | 24 Aug 2022 | 1,504 | 21,691 (0%) | 0% | 1.6 | 2,384 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2022 | 21,316 | 601,211 (3%) | 0% | 0 | Common Stock, par value $.0001 | |
| Tsontcho Ianchulev | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Aug 2022 | 30,399 | 30,399 | - | - | Stock Option (right to buy) | |
| Michael M. Rowe | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2022 | 440,000 | 440,000 | - | - | Stock Options (right to buy) | |
| Ellen R. Strahlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 20,187 | 20,187 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ellen R. Strahlman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 28,203 | - | - | - | Stock Option (right to buy) | |
| Ram Palanki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 28,203 | 28,203 | - | - | Stock Option (right to buy) | |
| Ram Palanki | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 20,187 | 20,187 (0%) | 0% | 0 | Common stock, par value $.0001 | |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.65 per share. | 21 Jun 2022 | 100,000 | 5,084,998 (29%) | 0% | 1.7 | 165,000 | Common stock, par value $0.0001 |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 22,222 | 64,544 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 30,769 | 30,769 | - | - | Stock Option (right to buy) | |
| Stephen K. Benjamin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 30,769 | 30,769 | - | - | Stock Option (right to buy) | |
| Stephen K. Benjamin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 22,222 | 25,511 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 22,222 | 70,544 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 30,769 | 30,769 | - | - | Stock Option (right to buy) | |
| Julia A. Haller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 22,222 | 30,408 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Julia A. Haller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 30,769 | 30,769 | - | - | Stock Option (right to buy) | |
| Rachel Jacobson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 30,769 | 30,769 | - | - | Stock Option (right to buy) | |
| Rachel Jacobson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2022 | 22,222 | - | 0% | 0 | Common Stock, par value $.0001 | |
| Kenneth B. Lee | Director | Purchase of securities on an exchange or from another person at price $ 2.20 per share. | 19 May 2022 | 10,000 | 42,322 (0%) | 0% | 2.2 | 22,000 | Common Stock, par value $.0001 |
| Charles E. Mather | Director | Purchase of securities on an exchange or from another person at price $ 2.03 per share. | 18 May 2022 | 7,000 | 48,322 (0%) | 0% | 2.0 | 14,232 | Common Stock, par value $.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.95 per share. | 10 May 2022 | 25,000 | 4,984,998 (29%) | 0% | 2.0 | 48,750 | Common stock, par value $0.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 1.98 per share. | 10 May 2022 | 50,000 | 4,959,998 (29%) | 0% | 2.0 | 99,000 | Common stock, par value $0.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.26 per share. | 04 May 2022 | 24,074 | 4,909,998 (28%) | 0% | 2.3 | 54,407 | Common stock, par value $0.0001 |
| Stuart M. Grant | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.26 per share. | 04 May 2022 | 25,926 | 4,935,924 (28%) | 0% | 2.3 | 58,593 | Common stock, par value $0.0001 |
| Stephen K. Benjamin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Apr 2022 | 4,745 | 4,745 | - | - | Stock Option (right to buy) | |
| Rachel Jacobson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Apr 2022 | 4,745 | 4,745 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | Director | Purchase of securities on an exchange or from another person at price $ 3.12 per share. | 31 Mar 2022 | 4,000 | 41,322 (0%) | 0% | 3.1 | 12,460 | Common Stock, par value $.0001 |
| John P. Gandolfo | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2022 | 23,211 | 23,211 | - | - | Stock Options (right to buy) | |
| Michael M. Rowe | CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2022 | 23,211 | 23,211 | - | - | Stock Options (right to buy) | |
| Fredric N. Eshelman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 9,653 | 9,653 | - | - | Stock Option (right to buy) | |
| Fredric N. Eshelman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 6,963 | 1,299,750 (7%) | 0% | 0 | Common Stock, par value $.0001 | |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 6,963 | 32,322 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 9,653 | 9,653 | - | - | Stock Option (right to buy) | |
| Ernest Mario | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 6,963 | 382,706 (2%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ernest Mario | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 9,653 | 9,653 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 9,653 | 9,653 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 6,963 | 37,322 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Anthony Y. Sun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 9,653 | 9,653 | - | - | Stock Option (right to buy) | |
| Anthony Y. Sun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 6,963 | 26,322 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Julia A. Haller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 6,963 | 8,186 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Julia A. Haller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 9,653 | 9,653 | - | - | Stock Option (right to buy) | |
| Curt H. LaBelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 9,653 | 9,653 | - | - | Stock Option (right to buy) | |
| Curt H. LaBelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2021 | 6,963 | 42,236 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Tsontcho Ianchulev | Director, CHIEF EXECUTIVE OFFICER | Purchase of securities on an exchange or from another person at price $ 4.04 per share. | 03 Nov 2021 | 30,000 | 579,895 (3%) | 0% | 4.0 | 121,206 | Common Stock, par value $.0001 |
| Charles E. Mather | Director | Purchase of securities on an exchange or from another person at price $ 3.83 per share. | 01 Nov 2021 | 4,000 | 30,359 (0%) | 0% | 3.8 | 15,314 | Common Stock, par value $.0001 |
| Michael M. Rowe | CHIEF OPERATING OFFICER | Purchase of securities on an exchange or from another person at price $ 4.14 per share. | 27 Oct 2021 | 1,200 | 5,500 (0%) | 0% | 4.1 | 4,968 | Common Stock, par value $.0001 |
| Michael M. Rowe | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 4.40 per share. | 13 Sep 2021 | 1,500 | 4,300 (0%) | 0% | 4.4 | 6,600 | Common Stock, par value $.0001 |
| Jennifer Clasby | VP, Regulatory and Clinical | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.42 per share. | 17 Jun 2021 | 13,675 | 66,537 (0%) | 0% | 5.4 | 74,119 | Common Stock |
| Jennifer Clasby | VP, Regulatory and Clinical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jun 2021 | 24,510 | 0 | - | - | Employee Stock Option (right to buy) | |
| Jennifer Clasby | VP, Regulatory and Clinical | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.95 per share. | 17 Jun 2021 | 24,510 | 80,212 (0%) | 0% | 2.0 | 47,795 | Common Stock |
| John P. Gandolfo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 128,258 | 128,258 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 139,867 | 139,867 | - | - | Stock Option (right to buy) | |
| Jennifer Clasby | VP, Regulatory and Clinical | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 128,258 | 128,258 | - | - | Stock Option (right to buy) | |
| Luke Clauson | VP Research & Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 128,258 | 128,258 | - | - | Stock Option (right to buy) | |
| Michael M. Rowe | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 128,258 | 128,258 | - | - | Stock Options (right to buy) | |
| Charles E. Mather | Director | Purchase of securities on an exchange or from another person at price $ 4.76 per share. | 28 May 2021 | 3,000 | 26,359 (0%) | 0% | 4.8 | 14,268 | Common Stock, par value $.0001 |
| Michael M. Rowe | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 4.71 per share. | 27 May 2021 | 1,400 | 2,800 (0%) | 0% | 4.7 | 6,594 | Common Stock, par value $.0001 |
| Julia A. Haller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2021 | 1,637 | 1,637 | - | - | Stock Option (right to buy) | |
| Julia A. Haller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2021 | 1,223 | 1,223 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ernest Mario | Director | 15 Jan 2021 | 41,216 | 375,743 (2%) | 0% | 2.3 | 93,560 | Common Stock, par value $.0001 | |
| Ernest Mario | Director | 15 Jan 2021 | 41,216 | 0 | - | - | Class A Warrant | ||
| Tsontcho Ianchulev | Director, Chief Executive Officer | 05 Jan 2021 | 41,216 | 0 | - | - | Class A Warrant | ||
| Tsontcho Ianchulev | Director, Chief Executive Officer | 05 Jan 2021 | 41,216 | 549,895 (3%) | 0% | 2.3 | 93,560 | Common Stock, par value $.0001 | |
| Tsontcho Ianchulev | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 20 Nov 2020 | 453,333 | 0 (0%) | 2% | 0 | Common Stock, par value $.0001 | |
| Curt LaBelle | Director | Other type of transaction at price $ 0.00 per share. | 20 Nov 2020 | 453,333 | 0 (0%) | 2% | 0 | Common Stock, par value $.0001 | |
| John P. Gandolfo | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 3.40 per share. | 19 Nov 2020 | 4,000 | 6,000 (0%) | 0% | 3.4 | 13,600 | Common Stock, par value $.0001 |
| Jennifer Clasby | VP, Clinical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Sep 2020 | 26,737 | 24,510 | - | - | Stock Option (right to buy) | |
| Jennifer Clasby | VP, Clinical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.95 per share. | 18 Sep 2020 | 26,737 | 55,702 (0%) | 0% | 1.9 | 52,137 | Common Stock |
| Fredric N. Eshelman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 9,820 | 9,820 | - | - | Stock Option (right to buy) | |
| Fredric N. Eshelman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 7,288 | 1,292,787 (7%) | 0% | 0 | Common Stock, par value $.0001 | |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 9,820 | 9,820 | - | - | Stock Option (right to buy) | |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 7,288 | 19,359 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ernest Mario | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 7,288 | 334,527 (1%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ernest Mario | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 9,820 | 9,820 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 7,288 | 23,359 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 9,820 | 9,820 | - | - | Stock Option (right to buy) | |
| Anthony Y. Sun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 7,288 | 19,359 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Anthony Y. Sun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 9,820 | 9,820 | - | - | Stock Option (right to buy) | |
| Curt LaBelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 9,820 | 9,820 | - | - | Stock Option (right to buy) | |
| Curt LaBelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Sep 2020 | 7,288 | 35,273 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| John P. Gandolfo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2020 | 114,774 | 114,774 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2020 | 285,255 | 285,255 | - | - | Stock Option (right to buy) | |
| Jennifer Clasby | VP, Clinical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2020 | 121,410 | 121,410 | - | - | Stock Option (right to buy) | |
| Luke Clauson | VP, R&D and Manufacturing | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2020 | 101,358 | 101,358 | - | - | Stock Option (right to buy) | |
| Michael M. Rowe | Vice President, Commercial | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2020 | 141,622 | 141,622 | - | - | Stock Option (right to buy) | |
| Ernest Mario | Director | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Mar 2020 | 41,216 | 41,216 | - | - | Class A Warrant | |
| Ernest Mario | Director | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Mar 2020 | 61,823 | 61,823 | - | - | Class B Warrant | |
| Ernest Mario | Director | Purchase of securities on an exchange or from another person at price $ 2.27 per share. | 24 Mar 2020 | 82,431 | 327,239 (1%) | 0% | 2.3 | 187,118 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.27 per share. | 24 Mar 2020 | 82,431 | 508,679 (2%) | 0% | 2.3 | 187,118 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Mar 2020 | 61,823 | 61,823 | - | - | Class B Warrant | |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Mar 2020 | 41,216 | 41,216 | - | - | Class A Warrant | |
| Michael M. Rowe | Vice President, Commercial | Purchase of securities on an exchange or from another person at price $ 3.84 per share. | 30 Sep 2019 | 100 | 1,400 (0%) | 0% | 3.8 | 384 | Common Stock, par value $.0001 |
| Fredric N. Eshelman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 9,057 | 9,057 | - | - | Stock Option (right to buy) | |
| Fredric N. Eshelman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 8,038 | 1,285,499 (7%) | 0% | 0 | Common Stock, par value $.0001 | |
| John P. Gandolfo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 53,402 | 53,402 | - | - | Stock Option (right to buy) | |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 9,057 | 9,057 | - | - | Stock Option (right to buy) | |
| Kenneth B. Lee | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 8,038 | 12,071 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Ernest Mario | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 9,057 | 9,057 | - | - | Stock Option (right to buy) | |
| Ernest Mario | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 8,038 | 280,779 (1%) | 0% | 0 | Common Stock, par value $.0001 | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 9,057 | 9,057 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 8,038 | 16,071 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Anthony Y. Sun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 8,038 | 12,071 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Anthony Y. Sun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 9,057 | 9,057 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 183,703 | 183,703 | - | - | Stock Option (right to buy) | |
| Jennifer Clasby | VP, Clinical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 42,722 | 42,722 | - | - | Stock Option (right to buy) | |
| Luke Clauson | VP, R&D and Manufacturing | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 42,722 | 42,722 | - | - | Stock Option (right to buy) | |
| Curt H. LaBelle | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 45,256 | 45,256 | - | - | Stock Option (right to buy) | |
| Michael M. Rowe | Vice President of Marketing | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2019 | 42,722 | 42,722 | - | - | Stock Option (right to buy) | |
| Ernest Mario | Director | Purchase of securities on an exchange or from another person at price $ 2.78 per share. | 11 Jul 2019 | 35,971 | 272,741 (1%) | 0% | 2.8 | 99,999 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 2.78 per share. | 11 Jul 2019 | 233,813 | 426,248 (2%) | 1% | 2.8 | 650,000 | Common Stock, par value $.0001 |
| Curt H. LaBelle | Director | Purchase of securities on an exchange or from another person at price $ 2.78 per share. | 11 Jul 2019 | 17,985 | 27,985 (0%) | 0% | 2.8 | 49,998 | Common Stock, par value $.0001 |
| Shuhei Yoshida | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.95 per share. | 14 May 2019 | 33,334 | 33,334 (0%) | 0% | 1.9 | 65,001 | Common Stock, par value $.0001 |
| Shuhei Yoshida | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2019 | 33,334 | 0 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.24 per share. | 02 Jan 2019 | 140,000 | 606,667 (3%) | 1% | 1.2 | 173,600 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.95 per share. | 02 Jan 2019 | 133,686 | 192,435 (1%) | 1% | 2.0 | 260,688 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.24 per share. | 02 Jan 2019 | 40,000 | 58,749 (0%) | 0% | 1.2 | 49,600 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2019 | 133,686 | 267,370 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2019 | 40,000 | 0 | - | - | Stock Option (right to buy) | |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2019 | 140,000 | 140,000 | - | - | Stock Option (right to buy) | |
| Curt H. LaBelle | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2019 | 140,000 | 140,000 | - | - | Stock Option (right to buy) | |
| Curt H. LaBelle | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.24 per share. | 02 Jan 2019 | 140,000 | 606,667 (3%) | 1% | 1.2 | 173,600 | Common Stock, par value $.0001 |
| Michael M. Rowe | Vice President of Marketing | Purchase of securities on an exchange or from another person at price $ 4.27 per share. | 24 Sep 2018 | 600 | 1,000 (0%) | 0% | 4.3 | 2,562 | Common Stock, par value $.0001 |
| Michael M. Rowe | Vice President of Marketing | Purchase of securities on an exchange or from another person at price $ 4.09 per share. | 24 Sep 2018 | 200 | 400 (0%) | 0% | 4.1 | 818 | Common Stock, par value $.0001 |
| Charles E. Mather | None | Purchase of securities on an exchange or from another person at price $ 4.78 per share. | 18 Sep 2018 | 3,000 | 8,033 (0%) | 0% | 4.8 | 14,340 | Common Stock, par value $.0001 |
| Charles E. Mather | None | Purchase of securities on an exchange or from another person at price $ 4.80 per share. | 18 Sep 2018 | 1,000 | 5,033 (0%) | 0% | 4.8 | 4,800 | Common Stock, par value $.0001 |
| Jennifer Clasby | VP, Clinical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Sep 2018 | 28,965 | 51,247 | - | - | Stock Option (right to buy) | |
| Jennifer Clasby | VP, Clinical Operations | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.95 per share. | 10 Sep 2018 | 28,965 | 28,965 (0%) | 0% | 2.0 | 56,482 | Common Stock |
| Fredric N. Eshelman | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,033 | 1,277,461 (12%) | 0% | 0 | Common Stock, par value $.0001 | |
| Fredric N. Eshelman | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,465 | 4,655 | - | - | Stock Option (right to buy) | |
| John P. Gandolfo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 24,842 | 24,842 | - | - | Stock Option (right to buy) | |
| Kenneth B. Lee | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,033 | 4,033 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Kenneth B. Lee | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,465 | 4,465 | - | - | Stock Option (right to buy) | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,465 | 4,465 | - | - | Stock Option (right to buy) | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,033 | 146,770 (1%) | 0% | 0 | Common Stock, par value $.0001 | |
| Charles E. Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,465 | 4,465 | - | - | Stock Option (right to buy) | |
| Charles E. Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,033 | 4,033 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Anthony Y. Sun | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,465 | 4,465 | - | - | Stock Option (right to buy) | |
| Anthony Y. Sun | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 4,033 | 4,033 (0%) | 0% | 0 | Common Stock, par value $.0001 | |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 124,210 | 124,210 | - | - | Stock Option (right to buy) | |
| Jennifer Clasby | VP, Clinical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 19,874 | 19,874 | - | - | Stock Option (right to buy) | |
| Luke Clauson | VP, Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 19,874 | 19,874 | - | - | Stock Option (right to buy) | |
| Michael M. Rowe | Vice President of Marketing | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2018 | 19,874 | 19,874 | - | - | Stock Option (right to buy) | |
| Michael M. Rowe | Vice President of Marketing | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jul 2018 | 60,000 | 60,000 | - | - | Stock Option (right to buy) | |
| John P. Gandolfo | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 5.86 per share. | 28 Jun 2018 | 2,000 | 2,000 (0%) | 0% | 5.9 | 11,720 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 6.63 per share. | 28 Jun 2018 | 6,000 | 6,000 (0%) | 0% | 6.6 | 39,780 | Common Stock, par value $.0001 |
| John P. Gandolfo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Apr 2018 | 71,200 | 71,200 | - | - | Stock Option (right to buy) | |
| Fredric N. Eshelman | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 29 Jan 2018 | 335,000 | 1,273,428 (12%) | 3% | 10 | 3,350,000 | Common Stock, par value $.0001 |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 29 Jan 2018 | 90,000 | 236,770 (2%) | 0% | 10 | 900,000 | Common Stock, par value $.0001 |
| Tsontcho Ianchulev | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 29 Jan 2018 | 10,000 | 18,749 (0%) | 0% | 10 | 100,000 | Common Stock, par value $.0001 |
| Curt LaBelle | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 29 Jan 2018 | 10,000 | 10,000 (0%) | 0% | 10 | 100,000 | Common Stock, par value $.0001 |
| Shuhei Yoshida | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 29 Jan 2018 | 100,000 | 1,718,566 (17%) | 1% | 10 | 1,000,000 | Common Stock, par value $.0001 |