1.7M XNAS Volume
XNAS 21 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 07 Mar 2025 | 100 | 14,578 | - | 0.2 | 18 | Common Stock |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 100 | 41,545 | - | - | Stock Option (Right to Buy) | |
| Kevin Koch | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 07 Mar 2025 | 100 | 14,478 | - | 30 | 3,000 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 30.02 per share. | 07 Mar 2025 | 200 | 14,863 | - | 30.0 | 6,004 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 200 | 1,456,580 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 07 Mar 2025 | 200 | 15,063 | - | 0.2 | 36 | Common Stock |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.11 per share. | 05 Feb 2025 | 900 | 15,378 | - | 13.1 | 11,799 | Common Stock |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 05 Feb 2025 | 8,636 | 23,114 | - | 0.2 | 1,554 | Common Stock |
| Kevin Koch | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.03 per share. | 05 Feb 2025 | 8,636 | 14,478 | - | 30.0 | 259,298 | Common Stock |
| Kevin Koch | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 31.13 per share. | 05 Feb 2025 | 900 | 14,478 | - | 31.1 | 28,018 | Common Stock |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Feb 2025 | 900 | 41,645 | - | - | Stock Option (Right to Buy) | |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Feb 2025 | 8,636 | 42,545 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Feb 2025 | 8,015 | 1,348,765 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 05 Feb 2025 | 8,015 | 22,878 | - | 0.2 | 1,443 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 30.02 per share. | 05 Feb 2025 | 8,015 | 14,863 | - | 30.0 | 240,623 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 05 Feb 2025 | 1,200 | 16,063 | - | 0.2 | 216 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 30.13 per share. | 05 Feb 2025 | 1,200 | 14,863 | - | 30.1 | 36,153 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Feb 2025 | 1,200 | 1,347,565 | - | - | Stock Option (Right to Buy) | |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Feb 2025 | 10,000 | 92,929 | - | - | Stock Option (Right to Buy) | |
| Behrad Derakhshan | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 30.03 per share. | 05 Feb 2025 | 10,000 | 16,837 | - | 30.0 | 300,300 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 05 Feb 2025 | 10,000 | 26,837 | - | 1.9 | 19,300 | Common Stock |
| Joanne M. Donovan | CMO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.08 per share. | 28 Jan 2025 | 25,000 | 41,358 | - | 7.1 | 177,000 | Common Stock |
| Joanne M. Donovan | CMO | Sale of securities on an exchange or to another person at price $ 27.63 per share. | 28 Jan 2025 | 25,000 | 16,358 | - | 27.6 | 690,658 | Common Stock |
| Joanne M. Donovan | CMO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jan 2025 | 25,000 | 175,000 | - | - | Stock Option (Right to Buy) | |
| Robert Blaustein | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jan 2025 | 30,000 | 30,000 | - | - | Restricted Stock Units | |
| Robert Blaustein | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jan 2025 | 160,000 | 160,000 | - | - | Stock Options (Right to buy) | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 30 Dec 2024 | 100,000 | 114,863 | - | 0.2 | 18,000 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 27.37 per share. | 30 Dec 2024 | 100,000 | 14,863 | - | 27.4 | 2,737,470 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Dec 2024 | 100,000 | 1,356,780 | - | - | Stock Option (Right to Buy) | |
| Marc Semigran | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 29.66 per share. | 24 Dec 2024 | 27,980 | 8,445 | - | 29.7 | 829,906 | Common Stock |
| Marc Semigran | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Dec 2024 | 29,709 | 270,291 | - | - | Stock Option (Right to Buy) | |
| Marc Semigran | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.94 per share. | 24 Dec 2024 | 29,709 | 36,425 | - | 8.9 | 265,598 | Common Stock |
| Marc Semigran | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 30.08 per share. | 24 Dec 2024 | 1,729 | 6,716 | - | 30.1 | 52,009 | Common Stock |
| Carruthers R. Michael | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 11 Oct 2024 | 70,000 | 76,904 | - | 0.7 | 49,700 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Oct 2024 | 70,000 | 127,122 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Sep 2024 | 20,922 | 41,636 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Sep 2024 | 50,000 | 62,558 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 27.63 per share. | 20 Sep 2024 | 20,922 | 3,252 | - | 27.6 | 578,064 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 20 Sep 2024 | 20,922 | 24,174 | - | 0.7 | 14,855 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 28.37 per share. | 20 Sep 2024 | 50,000 | 3,252 | - | 28.4 | 1,418,510 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 20 Sep 2024 | 50,000 | 53,252 | - | 0.7 | 35,500 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 28.55 per share. | 20 Sep 2024 | 50,000 | 6,904 | - | 28.5 | 1,427,385 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 28.59 per share. | 20 Sep 2024 | 24,960 | 6,904 | - | 28.6 | 713,512 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 28.59 per share. | 20 Sep 2024 | 4,064 | 31,864 | - | 28.6 | 116,174 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 28.59 per share. | 20 Sep 2024 | 46,068 | 35,928 | - | 28.6 | 1,316,909 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 20 Sep 2024 | 46,068 | 81,996 | - | 1.9 | 88,911 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 20 Sep 2024 | 50,000 | 56,904 | - | 1.9 | 96,500 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Sep 2024 | 96,068 | 40,990 | - | - | Stock Option (Right to Buy) | |
| Joanne M. Donovan | CMO | Sale of securities on an exchange or to another person at price $ 28.29 per share. | 20 Sep 2024 | 7,162 | 14,538 | - | 28.3 | 202,603 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 29.51 per share. | 20 Sep 2024 | 815 | 12,719 | - | 29.5 | 24,049 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Sep 2024 | 75,000 | 1,456,780 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 28.25 per share. | 20 Sep 2024 | 74,185 | 13,534 | - | 28.3 | 2,096,053 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 20 Sep 2024 | 75,000 | 87,719 | - | 0.2 | 13,500 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 20 Sep 2024 | 42,068 | 57,189 | - | 1.9 | 81,191 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 29.03 per share. | 20 Sep 2024 | 42,068 | 15,121 | - | 29.0 | 1,221,133 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Sep 2024 | 42,068 | 102,949 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 23,125 | 23,125 | - | - | Restricted Stock Units | |
| John R. Moore | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 138,750 | 138,750 | - | - | Stock Option (Right to Buy) | |
| Kevin Koch | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 431,250 | 431,250 | - | - | Stock Option (Right to Buy) | |
| Kevin Koch | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 71,875 | 71,875 | - | - | Restricted Stock Units | |
| R. Michael Carruthers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 138,750 | 138,750 | - | - | Stock Option (Right to Buy) | |
| R. Michael Carruthers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 23,125 | 23,125 | - | - | Restricted Stock Units | |
| Joanne M. Donovan | CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 138,750 | 138,750 | - | - | Stock Option (Right to Buy) | |
| Joanne M. Donovan | CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 23,125 | 23,125 | - | - | Restricted Stock Units | |
| Marc Semigran | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 138,750 | 138,750 | - | - | Stock Option (Right to Buy) | |
| Marc Semigran | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 23,125 | 23,125 | - | - | Restricted Stock Units | |
| Alan Russell | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 138,750 | 138,750 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 23,125 | 23,125 | - | - | Restricted Stock Units | |
| Behrad Derakhshan | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 138,750 | 138,750 | - | - | Stock Option (Right to Buy) | |
| Behrad Derakhshan | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2024 | 23,125 | 23,125 | - | - | Restricted Stock Units | |
| Arlene M. Morris | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 20,594 | 20,594 | - | - | Stock Option (Right to Buy) | |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 20,594 | 20,594 | - | - | Stock Option (Right to Buy) | |
| Jonathan D. Root | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 20,594 | 20,594 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 20,594 | 20,594 | - | - | Stock Options (Right to buy) | |
| Jonathan C. Fox | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 20,594 | 20,594 | - | - | Stock Option (Right to Buy) | |
| Badreddin Edris | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 20,594 | 20,594 | - | - | Stock Option (Right to Buy) | |
| Arlene M. Morris | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2024 | 34,311 | 34,311 | - | - | Stock Options (Right to buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 5,208 | - | 0 | Common Stock | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 01 May 2024 | 1,956 | 3,252 | - | 18.9 | 36,988 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 5,209 | - | - | Restricted Stock Units | |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 10,417 | 10,417 | - | - | Restricted Stock Units | |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 10,417 | 17,630 | - | 0 | Common Stock | |
| Kevin Koch | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 01 May 2024 | 3,152 | 14,478 | - | 18.9 | 59,604 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 37,387 | - | 0 | Common Stock | |
| R. Michael Carruthers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 01 May 2024 | 2,157 | 35,230 | - | 18.9 | 40,789 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 5,209 | - | - | Restricted Stock Units | |
| Joanne M. Donovan | CMO | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 01 May 2024 | 3,682 | 19,897 | - | 18.9 | 69,627 | Common Stock |
| Joanne M. Donovan | CMO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 10,417 | 10,417 | - | - | Restricted Stock Units | |
| Joanne M. Donovan | CMO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 10,417 | 23,579 | - | 0 | Common Stock | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 8,814 | - | 0 | Common Stock | |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 01 May 2024 | 1,576 | 7,238 | - | 18.9 | 29,802 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 5,209 | - | - | Restricted Stock Units | |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 15,140 | - | 0 | Common Stock | |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 5,208 | 5,209 | - | - | Restricted Stock Units | |
| Behrad Derakhshan | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 18.91 per share. | 01 May 2024 | 1,718 | 13,422 | - | 18.9 | 32,487 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2024 | 4,600 | 149,817 | - | - | Stock Option (Right to Buy) | |
| Moore John R. | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2024 | 8,029 | 93,162 | - | - | Stock Option (Right to Buy) | |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 07 Feb 2024 | 4,600 | 11,620 | - | 1.9 | 8,878 | Common Stock |
| Derakhshan Behrad | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 20.04 per share. | 07 Feb 2024 | 4,800 | 7,020 | - | 20.0 | 96,209 | Common Stock |
| R. John Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2024 | 3,813 | 101,191 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 07 Feb 2024 | 8,029 | 8,029 | - | 1.9 | 15,496 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 20.01 per share. | 07 Feb 2024 | 8,029 | 0 | - | 20.0 | 160,657 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 07 Feb 2024 | 17,993 | 0 | - | 20.0 | 359,864 | Common Stock |
| Moore John R. | General Counsel | Sale of securities on an exchange or to another person at price $ 20.01 per share. | 07 Feb 2024 | 3,813 | 0 | - | 20.0 | 76,285 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 20.01 per share. | 07 Feb 2024 | 4,600 | 7,020 | - | 20.0 | 92,049 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 07 Feb 2024 | 600 | 7,620 | - | 1.9 | 1,158 | Common Stock |
| Derakhshan Behrad | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2024 | 4,800 | 145,017 | - | - | Stock Option (Right to Buy) | |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2024 | 600 | 154,417 | - | - | Stock Option (Right to Buy) | |
| Derakhshan Behrad | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 07 Feb 2024 | 600 | 7,020 | - | 20 | 12,000 | Common Stock |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 07 Feb 2024 | 4,800 | 11,820 | - | 1.9 | 9,264 | Common Stock |
| R. Moore John | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 07 Feb 2024 | 3,813 | 3,813 | - | 1.9 | 7,359 | Common Stock |
| R. Moore John | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2024 | 17,993 | 105,004 | - | - | Stock Option (Right to Buy) | |
| R. Moore John | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 07 Feb 2024 | 17,993 | 17,993 | - | 1.9 | 34,726 | Common Stock |
| Carruthers Michael R. | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Jan 2024 | 90,000 | 137,058 | - | - | Stock Option (Right to Buy) | |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 23 Jan 2024 | 90,000 | 119,024 | - | 1.9 | 173,700 | Common Stock |
| Thompson Peter A. | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 11.00 per share. | 23 Jan 2024 | 454,545 | 14,436,497 | - | 11 | 4,999,995 | Common Stock |
| Michael R. Carruthers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 15.78 per share. | 23 Jan 2024 | 90,000 | 29,024 | - | 15.8 | 1,419,759 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 10.50 per share. | 27 Dec 2023 | 8,497 | 0 | - | 10.5 | 89,219 | Common Stock |
| C. Jonathan Fox | Director | Purchase of securities on an exchange or from another person at price $ 9.30 per share. | 26 Dec 2023 | 10,857 | 10,857 | - | 9.3 | 100,958 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.33 per share. | 26 Dec 2023 | 172,585 | 3,606 | - | 9.3 | 1,610,097 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 22 Jun 2023 | 10,000 | 29,024 | - | 0.7 | 7,100 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Jun 2023 | 10,000 | 197,122 | - | - | Stock Options (Right to buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 10,417 | - | - | Restricted Stock Units | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 8.91 per share. | 01 May 2023 | 1,897 | 6,565 | - | 8.9 | 16,893 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 8,462 | - | 0 | Common Stock | |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 10,416 | 20,834 | - | - | Restricted Stock Units | |
| Kevin Koch | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 10,416 | 10,416 | - | 0 | Common Stock | |
| Kevin Koch | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 8.90 per share. | 01 May 2023 | 3,203 | 7,213 | - | 8.9 | 28,522 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 17,462 | - | 0 | Common Stock | |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 10,417 | - | - | Restricted Stock Units | |
| R. Michael Carruthers | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 8.90 per share. | 01 May 2023 | 1,336 | 16,126 | - | 8.9 | 11,897 | Common Stock |
| Joanne M. Donovan | CMO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 10,416 | 13,214 | - | 0 | Common Stock | |
| Joanne M. Donovan | CMO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 10,416 | 20,834 | - | - | Restricted Stock Units | |
| Joanne M. Donovan | CMO | Sale of securities on an exchange or to another person at price $ 8.91 per share. | 01 May 2023 | 3,254 | 9,960 | - | 8.9 | 28,977 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 8.91 per share. | 01 May 2023 | 1,602 | 176,191 | - | 8.9 | 14,266 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 177,793 | - | 0 | Common Stock | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 10,417 | - | - | Restricted Stock Units | |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 10,417 | - | - | Restricted Stock Units | |
| Behrad Derakhshan | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2023 | 5,208 | 8,767 | - | 0 | Common Stock | |
| Behrad Derakhshan | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 8.90 per share. | 01 May 2023 | 1,747 | 7,020 | - | 8.9 | 15,557 | Common Stock |
| Jonathan C. Fox | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2023 | 43,731 | 43,731 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Oct 2022 | 4,730 | 122,997 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 03 Oct 2022 | 4,730 | 7,730 | - | 1.9 | 9,129 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 9.76 per share. | 03 Oct 2022 | 4,730 | 3,000 | - | 9.8 | 46,155 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 06 Sep 2022 | 4,730 | 7,730 | - | 1.9 | 9,129 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Sep 2022 | 4,730 | 127,727 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 10.99 per share. | 06 Sep 2022 | 2,351 | 3,000 | - | 11.0 | 25,842 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 10.83 per share. | 06 Sep 2022 | 2,379 | 5,351 | - | 10.8 | 25,756 | Common Stock |
| John R. Moore | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2022 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Kevin Koch | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2022 | 550,000 | 550,000 | - | - | Stock Option (Right to Buy) | |
| R. Michael Carruthers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2022 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Joanne M. Donovan | CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2022 | 240,000 | 240,000 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2022 | 220,000 | 220,000 | - | - | Stock Option (Right to Buy) | |
| Behrad Derakhshan | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2022 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 03 Aug 2022 | 4,502 | 12,232 | - | 0.7 | 3,196 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Aug 2022 | 4,502 | 112,558 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Aug 2022 | 4,730 | 132,457 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 9.31 per share. | 03 Aug 2022 | 9,232 | 3,000 | - | 9.3 | 85,921 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 03 Aug 2022 | 4,730 | 7,730 | - | 1.9 | 9,129 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 05 Jul 2022 | 4,502 | 11,186 | - | 0.7 | 3,196 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jul 2022 | 1,046 | 137,187 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jul 2022 | 4,502 | 117,060 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jul 2022 | 3,684 | 138,233 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 8.54 per share. | 05 Jul 2022 | 1,046 | 3,000 | - | 8.5 | 8,928 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 05 Jul 2022 | 1,046 | 4,046 | - | 1.9 | 2,019 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 8.35 per share. | 05 Jul 2022 | 8,186 | 3,000 | - | 8.3 | 68,329 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 05 Jul 2022 | 3,684 | 6,684 | - | 1.9 | 7,110 | Common Stock |
| Laura A. Brege | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 42,087 | 42,087 | - | - | Stock Option (Right to Buy) | |
| Jonathan D. Root | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 42,087 | 42,087 | - | - | Stock Option (Right to Buy) | |
| Badreddin Edris | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 42,087 | 42,087 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 16 Jun 2022 | 14,722 | 17,722 | - | 1.9 | 28,413 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 16 Jun 2022 | 22,127 | 25,127 | - | 1.9 | 42,705 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.62 per share. | 16 Jun 2022 | 22,127 | 3,000 | - | 6.6 | 146,434 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 16 Jun 2022 | 13,508 | 16,508 | - | 0.7 | 9,591 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 16 Jun 2022 | 17,570 | 34,078 | - | 1.9 | 33,910 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 13,508 | 121,562 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 17,570 | 141,917 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 22,127 | 159,487 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2022 | 14,722 | 181,614 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 7.29 per share. | 16 Jun 2022 | 31,078 | 3,000 | - | 7.3 | 226,695 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.17 per share. | 16 Jun 2022 | 14,722 | 3,000 | - | 6.2 | 90,805 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Jun 2022 | 3,628 | 153,145 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 13 Jun 2022 | 4,093 | 7,093 | - | 0.7 | 2,906 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.01 per share. | 13 Jun 2022 | 4,093 | 3,000 | - | 6.0 | 24,582 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 13 Jun 2022 | 3,628 | 6,628 | - | 0.7 | 2,576 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.02 per share. | 13 Jun 2022 | 3,628 | 3,000 | - | 6.0 | 21,855 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 13 Jun 2022 | 18,075 | 21,075 | - | 0.7 | 12,833 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 13 Jun 2022 | 585 | 21,660 | - | 1.9 | 1,129 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.11 per share. | 13 Jun 2022 | 585 | 21,075 | - | 6.1 | 3,575 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.11 per share. | 13 Jun 2022 | 18,075 | 3,000 | - | 6.1 | 110,445 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Jun 2022 | 4,093 | 156,773 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Jun 2022 | 18,075 | 135,070 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Jun 2022 | 585 | 196,336 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jun 2022 | 12,566 | 175,606 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.05 per share. | 08 Jun 2022 | 7,125 | 3,000 | - | 6.1 | 43,120 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 08 Jun 2022 | 7,125 | 10,125 | - | 0.7 | 5,059 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.49 per share. | 08 Jun 2022 | 7,615 | 3,000 | - | 6.5 | 49,397 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 08 Jun 2022 | 7,615 | 10,615 | - | 0.7 | 5,407 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.63 per share. | 08 Jun 2022 | 12,566 | 3,000 | - | 6.6 | 83,362 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 08 Jun 2022 | 12,566 | 15,566 | - | 0.7 | 8,922 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jun 2022 | 7,125 | 160,866 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jun 2022 | 7,615 | 167,991 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.03 per share. | 03 Jun 2022 | 13,934 | 3,000 | - | 6.0 | 84,085 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 03 Jun 2022 | 13,934 | 16,934 | - | 1.9 | 26,893 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 03 Jun 2022 | 15,230 | 18,230 | - | 1.9 | 29,394 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.05 per share. | 03 Jun 2022 | 15,230 | 3,000 | - | 6.1 | 92,198 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 17,150 | 188,172 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 973 | 196,921 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 13,934 | 197,894 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2022 | 15,230 | 211,828 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.61 per share. | 03 Jun 2022 | 17,150 | 3,000 | - | 6.6 | 113,276 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 03 Jun 2022 | 17,150 | 20,150 | - | 0.7 | 12,177 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 6.61 per share. | 03 Jun 2022 | 973 | 3,000 | - | 6.6 | 6,427 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.93 per share. | 03 Jun 2022 | 973 | 3,973 | - | 1.9 | 1,878 | Common Stock |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 May 2022 | 9,000 | 207,122 | - | - | Stock Option (Right to Buy) | |
| R. Michael Carruthers | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 23 May 2022 | 9,000 | 12,000 | - | 0.7 | 6,390 | Common Stock |
| John R. Moore | General Counsel | Sale of securities on an exchange or to another person at price $ 7.42 per share. | 16 May 2022 | 10,800 | 3,000 | - | 7.4 | 80,146 | Common Stock |
| John R. Moore | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2022 | 15,625 | 15,625 | - | - | Restricted Stock Units | |
| Kevin Koch | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2022 | 31,250 | 31,250 | - | - | Restricted Stock Units | |
| R. Michael Carruthers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2022 | 15,625 | 15,625 | - | - | Restricted Stock Units | |
| Joanne M. Donovan | CMO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2022 | 31,250 | 31,250 | - | - | Restricted Stock Units | |
| Alan Russell | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2022 | 15,625 | 15,625 | - | - | Restricted Stock Units | |
| Behrad Derakhshan | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2022 | 15,625 | 15,625 | - | - | Restricted Stock Units | |
| Jonathan D. Root | Director | Other type of transaction at price $ 0.00 per share. | 25 Feb 2022 | 3,473,543 | 0 | - | - | Common Stock | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Jan 2022 | 5,400 | 205,322 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 21 Jan 2022 | 5,400 | 12,362 | - | 0.7 | 3,834 | Common Stock |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Dec 2021 | 5,400 | 210,722 | - | - | Stock Option (Right to Buy) | |
| John R. Moore | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.71 per share. | 28 Dec 2021 | 5,400 | 6,962 | - | 0.7 | 3,834 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.18 per share. | 30 Nov 2021 | 147,585 | 147,585 | - | 0.2 | 26,565 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Nov 2021 | 25,000 | 130,352 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Nov 2021 | 147,585 | 0 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.45 per share. | 30 Nov 2021 | 25,000 | 172,585 | - | 0.5 | 11,250 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.61 per share. | 15 Nov 2021 | 38 | 0 | - | 19.6 | 745 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.07 per share. | 15 Nov 2021 | 441 | 38 | - | 19.1 | 8,410 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.30 per share. | 09 Nov 2021 | 12,712 | 40,643 | - | 20.3 | 258,031 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.51 per share. | 09 Nov 2021 | 8,562 | 479 | - | 19.5 | 167,074 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.43 per share. | 09 Nov 2021 | 3,681 | 9,041 | - | 20.4 | 75,195 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.82 per share. | 09 Nov 2021 | 15,595 | 12,722 | - | 19.8 | 309,043 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.21 per share. | 09 Nov 2021 | 580 | 28,317 | - | 20.2 | 11,723 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.70 per share. | 09 Nov 2021 | 11,746 | 28,897 | - | 19.7 | 231,447 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.94 per share. | 09 Nov 2021 | 16,864 | 53,355 | - | 19.9 | 336,275 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.67 per share. | 04 Nov 2021 | 6 | 92,272 | - | 20.7 | 124 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.16 per share. | 04 Nov 2021 | 9,017 | 70,219 | - | 20.2 | 181,824 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.62 per share. | 04 Nov 2021 | 13,036 | 79,236 | - | 19.6 | 255,783 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.76 per share. | 04 Nov 2021 | 7,392 | 92,278 | - | 19.8 | 146,092 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.84 per share. | 01 Nov 2021 | 4,243 | 100,789 | - | 18.8 | 79,944 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.42 per share. | 01 Nov 2021 | 1,119 | 99,670 | - | 19.4 | 21,726 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.98 per share. | 01 Nov 2021 | 20,822 | 105,032 | - | 18.0 | 374,425 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.43 per share. | 01 Nov 2021 | 17,519 | 125,854 | - | 17.4 | 305,360 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.03 per share. | 01 Nov 2021 | 469 | 143,373 | - | 18.0 | 8,454 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.18 per share. | 14 Oct 2021 | 5,749 | 145,275 | - | 18.2 | 104,517 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.00 per share. | 14 Oct 2021 | 126 | 143,842 | - | 18 | 2,268 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.13 per share. | 14 Oct 2021 | 1,307 | 143,968 | - | 18.1 | 23,698 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.02 per share. | 11 Oct 2021 | 1,270 | 151,024 | - | 18.0 | 22,885 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.03 per share. | 06 Oct 2021 | 2,108 | 171,214 | - | 18.0 | 38,007 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.15 per share. | 06 Oct 2021 | 5,902 | 152,294 | - | 18.1 | 107,121 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.56 per share. | 06 Oct 2021 | 13,018 | 158,196 | - | 18.6 | 241,614 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.00 per share. | 01 Oct 2021 | 100 | 178,726 | - | 18 | 1,800 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.26 per share. | 01 Oct 2021 | 5,404 | 173,322 | - | 18.3 | 98,677 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.00 per share. | 01 Oct 2021 | 274 | 178,826 | - | 18 | 4,932 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 16.83 per share. | 28 Sep 2021 | 11,226 | 179,718 | - | 16.8 | 188,934 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.47 per share. | 28 Sep 2021 | 618 | 179,100 | - | 17.5 | 10,796 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.30 per share. | 28 Sep 2021 | 14,610 | 190,944 | - | 17.3 | 252,753 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.42 per share. | 23 Sep 2021 | 5,072 | 237,265 | - | 19.4 | 98,498 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.47 per share. | 23 Sep 2021 | 17 | 205,554 | - | 18.5 | 314 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.98 per share. | 23 Sep 2021 | 11,594 | 205,571 | - | 18.0 | 208,460 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.34 per share. | 23 Sep 2021 | 21,763 | 242,337 | - | 18.3 | 399,133 | Common Stock |
| Alan Russell | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.16 per share. | 23 Sep 2021 | 20,100 | 217,165 | - | 18.2 | 365,016 | Common Stock |
| John R. Moore | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2021 | 120,000 | 120,000 | - | - | Stock Option (Right to Buy) | |
| Kevin Koch | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2021 | 400,000 | 400,000 | - | - | Stock Option (Right to Buy) | |
| R. Michael Carruthers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2021 | 120,000 | 120,000 | - | - | Stock Option (Right to Buy) | |
| Alan Russell | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2021 | 120,000 | 120,000 | - | - | Stock Option (Right to Buy) | |
| Behrad Derakhshan | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Aug 2021 | 140,000 | 140,000 | - | - | Stock Option (Right to Buy) | |
| Jonathan D. Root | Director | 30 Mar 2021 | 1,651,607 | 0 | - | - | Series B-1 Preferred Stock | ||
| Jonathan D. Root | Director | Purchase of securities on an exchange or from another person at price $ 16.00 per share. | 30 Mar 2021 | 15,625 | 15,625 | - | 16 | 250,000 | Common Stock |
| Jonathan D. Root | Director | 30 Mar 2021 | 455,229 | 0 | - | - | Series C Preferred Stock | ||
| Jonathan D. Root | Director | 30 Mar 2021 | 1,366,707 | 0 | - | - | Series B-2 Preferred Stock | ||
| Jonathan D. Root | Director | 30 Mar 2021 | 3,473,543 | 3,473,543 | - | 0 | Common Stock |