2.8M XNAS Volume
XNAS 21 Mar, 2025 2:23 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Sheldon L. Koenig | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.50 per share. | 18 Mar 2025 | 13,047 | 1,571,962 (5%) | 0% | 1.5 | 19,623 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.49 per share. | 18 Mar 2025 | 2,433 | 370,326 (1%) | 0% | 1.5 | 3,618 | Common Stock |
| Benjamin Halladay | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.48 per share. | 18 Mar 2025 | 3,535 | 481,710 (1%) | 0% | 1.5 | 5,242 | Common Stock |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 238,000 | 485,245 (1%) | 0% | 0 | Common Stock | |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 213,000 | 213,000 | - | - | Stock Option (right to buy) | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 753,000 | 753,000 | - | - | Stock Option (right to buy | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 840,000 | 1,585,009 (5%) | 3% | 0 | Common Stock | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 224,000 | 407,663 (1%) | 0% | 0 | Common Stock | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 201,000 | 201,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 213,000 | 372,759 (1%) | 0% | 0 | Common Stock | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2025 | 191,000 | 191,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.87 per share. | 19 Feb 2025 | 239 | 159,759 (0%) | 0% | 1.9 | 446 | Common Stock |
| Benjamin Halladay | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.82 per share. | 19 Feb 2025 | 11 | 240,671 (0%) | 0% | 1.8 | 20 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.26 per share. | 17 Jan 2025 | 123 | 159,998 (0%) | 0% | 2.3 | 278 | Common Stock |
| Benjamin Halladay | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.22 per share. | 17 Jan 2025 | 9 | 240,682 (0%) | 0% | 2.2 | 20 | Common Stock |
| Halladay Benjamin | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.42 per share. | 17 Dec 2024 | 3,245 | 240,691 (0%) | 0% | 2.4 | 7,866 | Common Stock |
| L. Koenig Sheldon | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.47 per share. | 17 Dec 2024 | 12,447 | 739,819 (2%) | 0% | 2.5 | 30,694 | Common Stock |
| Warren Eric | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.43 per share. | 17 Dec 2024 | 2,234 | 160,121 (0%) | 0% | 2.4 | 5,426 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.17 per share. | 19 Nov 2024 | 197 | 162,355 (0%) | 0% | 2.2 | 427 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.12 per share. | 17 Oct 2024 | 107 | 162,552 (0%) | 0% | 2.1 | 227 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.80 per share. | 17 Sep 2024 | 14,550 | 752,266 (2%) | 0% | 1.8 | 26,132 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.78 per share. | 17 Sep 2024 | 2,608 | 162,659 (0%) | 0% | 1.8 | 4,650 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 19 Aug 2024 | 211 | 165,267 (0%) | 0% | 1.9 | 411 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.60 per share. | 17 Jul 2024 | 917 | 272,862 (0%) | 0% | 2.6 | 2,383 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.58 per share. | 17 Jul 2024 | 108 | 165,478 (0%) | 0% | 2.6 | 279 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.87 per share. | 18 Jun 2024 | 3,285 | 273,779 (0%) | 0% | 2.9 | 9,418 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.86 per share. | 18 Jun 2024 | 2,540 | 165,586 (0%) | 0% | 2.9 | 7,254 | Common Stock |
| Antonio M. Gotto | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 23,000 | 51,599 (0%) | 0% | 0 | Common Stock | |
| Antonio M. Gotto | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| Stephen C. Rocamboli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 23,000 | 36,261 (0%) | 0% | 0 | Common Stock | |
| Stephen C. Rocamboli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 65,000 | 65,000 | - | - | Stock Option (right to buy) | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 23,000 | 53,404 (0%) | 0% | 0 | Common Stock | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 23,000 | 51,599 (0%) | 0% | 0 | Common Stock | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| Seth H.Z. Fischer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| Seth H.Z. Fischer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 23,000 | 28,150 (0%) | 0% | 0 | Common Stock | |
| J. Martin Carroll | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 32,500 | 32,500 | - | - | Stock Option (right to buy) | |
| J. Martin Carroll | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 23,000 | 64,650 (0%) | 0% | 0 | Common Stock | |
| Tracy M. Woody | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 65,000 | 65,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.48 per share. | 17 May 2024 | 192 | 168,126 (0%) | 0% | 2.5 | 477 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 454,000 | 766,816 (2%) | 1% | 0 | Common Stock | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 642,000 | 642,000 | - | - | Stock Option (right to buy) | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 100,000 | 183,663 (0%) | 0% | 0 | Common Stock | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 150,000 | 277,064 (1%) | 0% | 0 | Common Stock | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 100,000 | 168,318 (0%) | 0% | 0 | Common Stock | |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 170,000 | 243,936 (0%) | 0% | 0 | Common Stock | |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2024 | 200,000 | 200,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.42 per share. | 18 Aug 2023 | 243 | 69,060 (0%) | 0% | 1.4 | 344 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2023 | 44,650 | 44,650 | - | - | Stock Option (right to buy) | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2023 | 44,650 | 44,650 | - | - | Stock Option (right to buy | |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.58 per share. | 19 Jul 2023 | 106 | 69,303 (0%) | 0% | 1.6 | 168 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.48 per share. | 21 Jun 2023 | 603 | 69,409 (0%) | 0% | 1.5 | 894 | Common Stock |
| Antonio M. Gotto | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 28,599 (0%) | 0% | 0 | Common Stock | |
| Antonio M. Gotto | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| Stephen C. Rocamboli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| Stephen C. Rocamboli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 13,261 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 36,918 (0%) | 0% | 0 | Common Stock | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 30,404 (0%) | 0% | 0 | Common Stock | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 28,599 (0%) | 0% | 0 | Common Stock | |
| Seth H.Z. Fischer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 5,150 (0%) | 0% | 0 | Common Stock | |
| Seth H.Z. Fischer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| J. Martin Carroll | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| J. Martin Carroll | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 41,650 (0%) | 0% | 0 | Common Stock | |
| Tracy M. Woody | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 21,000 | 21,000 | - | - | Stock Option (right to buy) | |
| Tracy M. Woody | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 5,150 | 33,566 (0%) | 0% | 0 | Common Stock | |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.63 per share. | 17 May 2023 | 219 | 70,012 (0%) | 0% | 1.6 | 356 | Common Stock |
| Stephen C. Rocamboli | Director | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 10 May 2023 | 8,111 | 8,111 (0%) | 0% | 1.5 | 12,126 | Common Stock |
| J. Martin Carroll | Director | Purchase of securities on an exchange or from another person at price $ 1.49 per share. | 10 May 2023 | 8,409 | 13,409 (0%) | 0% | 1.5 | 12,545 | Common Stock |
| J. Martin Carroll | Director | Purchase of securities on an exchange or from another person at price $ 1.57 per share. | 10 May 2023 | 23,091 | 36,500 (0%) | 0% | 1.6 | 36,285 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.26 per share. | 09 May 2023 | 20,000 | 312,816 (1%) | 0% | 1.3 | 25,192 | Common Stock |
| Benjamin O. Looker | General Counsel | Sale of securities on an exchange or to another person at price $ 1.27 per share. | 19 Apr 2023 | 1,290 | 83,663 (0%) | 0% | 1.3 | 1,641 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.27 per share. | 19 Apr 2023 | 938 | 127,064 (0%) | 0% | 1.3 | 1,192 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.28 per share. | 19 Apr 2023 | 115 | 70,231 (0%) | 0% | 1.3 | 147 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.78 per share. | 17 Mar 2023 | 6,999 | 292,816 (1%) | 0% | 1.8 | 12,479 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.78 per share. | 17 Mar 2023 | 3,808 | 128,002 (0%) | 0% | 1.8 | 6,785 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.78 per share. | 17 Mar 2023 | 526 | 70,346 (0%) | 0% | 1.8 | 937 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 445,000 | 445,000 | - | - | Stock Option (right to buy) | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 105,000 | 299,815 (1%) | 0% | 0 | Common Stock | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 20,500 | 84,953 (0%) | 0% | 0 | Common Stock | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 86,900 | 86,900 | - | - | Stock Option (right to buy) | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 122,500 | 122,500 | - | - | Stock Option (right to buy) | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 28,750 | 131,810 (0%) | 0% | 0 | Common Stock | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 22,300 | 70,872 (0%) | 0% | 0 | Common Stock | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 94,500 | 94,500 | - | - | Stock Option (right to buy) | |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 9,200 | 73,936 (0%) | 0% | 0 | Common Stock | |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 39,000 | 39,000 | - | - | Stock Option (right to buy) | |
| Sheldon L. Koenig | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 5.06 per share. | 07 Mar 2023 | 5,441 | 194,815 (0%) | 0% | 5.1 | 27,510 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.06 per share. | 07 Mar 2023 | 3,884 | 103,060 (0%) | 0% | 5.1 | 19,672 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 5.06 per share. | 07 Mar 2023 | 5,090 | 48,572 (0%) | 0% | 5.1 | 25,730 | Common Stock |
| Benjamin O. Looker | General Counsel | Sale of securities on an exchange or to another person at price $ 7.00 per share. | 18 Jan 2023 | 6,347 | 64,453 (0%) | 0% | 7.0 | 44,404 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 6.98 per share. | 18 Jan 2023 | 1,191 | 106,944 (0%) | 0% | 7.0 | 8,319 | Common Stock |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2022 | 44,000 | 63,771 (0%) | 0% | 0 | Common Stock | |
| Benjamin Halladay | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2022 | 66,000 | 66,000 | - | - | Stock Option (right to buy) | |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.69 per share. | 18 Oct 2022 | 942 | 108,135 (0%) | 0% | 7.7 | 7,242 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 7.69 per share. | 18 Oct 2022 | 107 | 53,662 (0%) | 0% | 7.7 | 823 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 6.94 per share. | 19 Sep 2022 | 3,394 | 198,257 (0%) | 0% | 6.9 | 23,548 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 6.92 per share. | 19 Sep 2022 | 255 | 53,769 (0%) | 0% | 6.9 | 1,765 | Common Stock |
| Eric Warren | Chief Commercial Officer | Purchase of securities on an exchange or from another person at price $ 7.46 per share. | 31 Aug 2022 | 1,000 | 54,024 (0%) | 0% | 7.5 | 7,460 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 6.81 per share. | 17 Aug 2022 | 199 | 53,024 (0%) | 0% | 6.8 | 1,356 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 5.80 per share. | 05 Aug 2022 | 8,606 | 198,771 (0%) | 0% | 5.8 | 49,950 | Common Stock |
| JoAnne Micale Foody | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 6.55 per share. | 19 Jul 2022 | 3,901 | 109,077 (0%) | 0% | 6.6 | 25,552 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 6.58 per share. | 19 Jul 2022 | 431 | 53,223 (0%) | 0% | 6.6 | 2,837 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.99 per share. | 17 Jun 2022 | 4,552 | 190,165 (0%) | 0% | 5.0 | 22,719 | Common Stock |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 4.90 per share. | 17 Jun 2022 | 256 | 53,654 (0%) | 0% | 4.9 | 1,254 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 91,000 | 91,000 | - | - | Stock Option (right to buy) | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 52,000 | 52,000 | - | - | Stock Option (right to buy) | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 52,000 | 52,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 52,000 | 52,000 | - | - | Stock Option (right to buy) | |
| J. Martin Carroll | Director | Purchase of securities on an exchange or from another person at price $ 5.64 per share. | 02 Jun 2022 | 5,000 | 5,000 (0%) | 0% | 5.6 | 28,180 | Common Stock |
| J. Martin Carroll | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Antonio M. Gotto | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Stephen C. Rocamboli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 1,589 | 1,589 | - | - | Stock Option (right to buy) | |
| Stephen C. Rocamboli | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Seth H.Z. Fischer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 11,561 | 11,561 | - | - | Stock Option (right to buy | |
| Jeffrey Berkowitz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Tracy M. Woody | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2022 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Eric Warren | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 5.98 per share. | 17 May 2022 | 196 | 53,910 (0%) | 0% | 6.0 | 1,172 | Common Stock |
| Sheldon L. Koenig | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.58 per share. | 17 Mar 2022 | 571 | 194,717 (0%) | 0% | 4.6 | 2,615 | Common Stock |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 37,000 | 82,751 (0%) | 0% | 0 | Common Stock | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 116,000 | 195,288 (0%) | 0% | 0 | Common Stock | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 28,000 | 112,978 (0%) | 0% | 0 | Common Stock | |
| Eric Warren | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 13,000 | 54,106 (0%) | 0% | 0 | Common Stock | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 70,800 | 70,800 (0%) | 0% | 0 | Common Stock | |
| Benjamin O. Looker | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 100,450 | 100,450 | - | - | Stock Option (right to buy) | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2021 | 18,700 | 43,852 (0%) | 0% | 0 | Common Stock | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2021 | 26,700 | 76,700 (0%) | 0% | 0 | Common Stock | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2021 | 22,450 | 84,978 (0%) | 0% | 0 | Common Stock | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2021 | 37,500 | 37,500 | - | - | Stock Option (right to buy) | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2021 | 26,400 | 26,400 | - | - | Performance-based Restricted Stock Units | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2021 | 62,528 | 62,528 (0%) | 0% | 0 | Common Stock | |
| JoAnne Micale Foody | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jun 2021 | 88,692 | 88,692 | - | - | Stock Option (right to buy) | |
| Antonio M. Gotto | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 23,449 (0%) | 0% | 0 | Common Stock | |
| Daniel S. Janney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 23,449 (0%) | 0% | 0 | Common Stock | |
| Mark E. McGovern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 28,449 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 31,768 (0%) | 0% | 0 | Common Stock | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 25,254 (0%) | 0% | 0 | Common Stock | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 23,449 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Berkowitz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 23,449 (0%) | 0% | 0 | Common Stock | |
| Tracy M. Woody | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2021 | 12,376 | 28,416 (0%) | 0% | 0 | Common Stock | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2021 | 120,000 | 120,000 | - | - | Stock Option (right to buy) | |
| Sheldon L. Koenig | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2021 | 20,000 | 50,000 (0%) | 0% | 0 | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2021 | 175,000 | 175,000 | - | - | Stock Option (right to buy) | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2021 | 5,000 | 23,617 (0%) | 0% | 0 | Common Stock | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2021 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Sheldon L. Koenig | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2021 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Sheldon L. Koenig | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2021 | 30,000 | 30,000 (0%) | 0% | 0 | Common Stock | |
| Ashley Hall | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2021 | 31,000 | 31,000 | - | - | Stock Option (right to buy) | |
| Ashley Hall | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2021 | 7,000 | 22,500 (0%) | 0% | 0 | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Dec 2020 | 10,700 | 262,959 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.10 per share. | 30 Dec 2020 | 10,700 | 122,698 (0%) | 0% | 2.1 | 22,427 | Common Stock |
| Antonio M. Gotto | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 6,106 | 11,073 (0%) | 0% | 0 | Common Stock | |
| Daniel S. Janney | Director | Other type of transaction at price $ 0.00 per share. | 28 May 2020 | 24,565 | 24,565 (0%) | 0% | 0 | Common Stock | |
| Daniel S. Janney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 6,106 | 11,073 (0%) | 0% | 0 | Common Stock | |
| Mark E. McGovern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 6,106 | 16,073 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 6,106 | 19,392 (0%) | 0% | 0 | Common Stock | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 1,221 | 12,878 (0%) | 0% | 0 | Common Stock | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 6,106 | 11,073 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Berkowitz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 6,106 | 11,073 (0%) | 0% | 0 | Common Stock | |
| Tracy M. Woody | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2020 | 6,106 | 16,040 (0%) | 0% | 0 | Common Stock | |
| Alan Fuhrman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2020 | 11,003 | 11,657 (0%) | 0% | 0 | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 43.00 per share. | 11 Mar 2020 | 2,500 | 111,998 (0%) | 0% | 43 | 107,500 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 49.00 per share. | 28 Feb 2020 | 5,000 | 109,498 (0%) | 0% | 49 | 245,000 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 23,150 | 104,498 (0%) | 0% | 0 | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Jan 2020 | 1,950 | 81,173 (0%) | 0% | 0 | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Jan 2020 | 365 | 81,348 (0%) | 0% | 0 | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 104,175 | 104,175 | - | - | Stock Option (right to buy) | |
| Mark A. Glickman | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 26,625 | 26,625 | - | - | Stock Option (right to buy | |
| Mark A. Glickman | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 5,925 | 25,925 (0%) | 0% | 0 | Common Stock | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 33,900 | 33,900 | - | - | Stock Option (right to buy) | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 7,525 | 18,673 (0%) | 0% | 0 | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 36.98 per share. | 06 Nov 2019 | 5,000 | 83,663 (0%) | 0% | 37.0 | 184,900 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 35.25 per share. | 04 Sep 2019 | 2,500 | 78,663 (0%) | 0% | 35.3 | 88,125 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 33.42 per share. | 04 Sep 2019 | 148 | 76,163 (0%) | 0% | 33.4 | 4,946 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 34.22 per share. | 04 Sep 2019 | 4,852 | 76,015 (0%) | 0% | 34.2 | 166,035 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 39.56 per share. | 01 Aug 2019 | 5,000 | 71,163 (0%) | 0% | 39.6 | 197,800 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 46.00 per share. | 28 Jun 2019 | 5,000 | 66,163 (0%) | 0% | 46 | 230,000 | Common Stock |
| Antonio M. Gotto | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 4,967 | 4,967 (0%) | 0% | 0 | Common Stock | |
| Mark E. McGovern | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 4,967 | 9,967 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 4,967 | 13,286 (0%) | 0% | 0 | Common Stock | |
| Jay P. Shepard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 4,967 | 4,967 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Berkowitz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 4,967 | 4,967 (0%) | 0% | 0 | Common Stock | |
| Tracy M. Woody | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 9,934 | 9,934 (0%) | 0% | 0 | Common Stock | |
| Scott Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 4,967 | 5,019 (0%) | 0% | 0 | Common Stock | |
| Richard B. Bartram | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 43.62 per share. | 03 Apr 2019 | 1,500 | 11,092 (0%) | 0% | 43.6 | 65,430 | Common Stock |
| Richard B. Bartram | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 42.71 per share. | 03 Apr 2019 | 6,500 | 12,592 (0%) | 0% | 42.7 | 277,615 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 40.00 per share. | 29 Mar 2019 | 5,000 | 61,163 (0%) | 0% | 40 | 200,000 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 43.48 per share. | 20 Mar 2019 | 5,000 | 56,163 (0%) | 0% | 43.5 | 217,400 | Common Stock |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 19 Mar 2019 | 1,101,080 | 0 (0%) | 4% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 19 Mar 2019 | 17,790 | 17,790 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 19 Mar 2019 | 1,356 | 8,319 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 19 Mar 2019 | 17,790 | 0 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Sale of securities on an exchange or to another person at price $ 45.25 per share. | 19 Mar 2019 | 1,700 | 0 (0%) | 0% | 45.3 | 76,925 | Common Stock |
| Nicole Vitullo | None | Sale of securities on an exchange or to another person at price $ 44.66 per share. | 19 Mar 2019 | 13,629 | 1,700 (0%) | 0% | 44.7 | 608,671 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 48.73 per share. | 14 Mar 2019 | 5,000 | 51,163 (0%) | 0% | 48.7 | 243,650 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.06 per share. | 12 Mar 2019 | 25,000 | 548,726 (1%) | 0% | 50.1 | 1,251,500 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Nov 2018 | 110,000 | 110,000 | - | - | Stock Option (right to buy) | |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Nov 2018 | 12,000 | 12,000 | - | - | Stock Option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Nov 2018 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.76 per share. | 01 Nov 2018 | 227 | 573,726 (2%) | 0% | 50.8 | 11,523 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.01 per share. | 01 Nov 2018 | 2,600 | 573,953 (2%) | 0% | 50.0 | 130,026 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.02 per share. | 16 Oct 2018 | 12,673 | 576,653 (2%) | 0% | 50.0 | 633,903 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.01 per share. | 16 Oct 2018 | 9,400 | 589,326 (2%) | 0% | 50.0 | 470,094 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 16 Oct 2018 | 100 | 576,553 (2%) | 0% | 50 | 5,000 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 53.68 per share. | 27 Aug 2018 | 700 | 615,726 (2%) | 0% | 53.7 | 37,576 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.65 per share. | 27 Aug 2018 | 12,100 | 598,726 (2%) | 0% | 50.7 | 612,865 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 51.46 per share. | 27 Aug 2018 | 4,200 | 610,826 (2%) | 0% | 51.5 | 216,132 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 52.91 per share. | 27 Aug 2018 | 700 | 615,026 (2%) | 0% | 52.9 | 37,037 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 50.06 per share. | 17 Aug 2018 | 7,300 | 616,426 (2%) | 0% | 50.1 | 365,438 | Common Stock |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 22 Jun 2018 | 3,846 | 6,963 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 22 Jun 2018 | 21,471 | 0 (0%) | 0% | 0 | Common Stock | |
| Dov A. Goldstein | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.42 per share. | 06 Jun 2018 | 5,000 | 5,047 (0%) | 0% | 14.4 | 72,100 | Common Stock |
| Dov A. Goldstein | None | Other type of transaction at price $ 0.00 per share. | 06 Jun 2018 | 5,000 | 8,047 (0%) | 0% | 0 | Common Stock | |
| Dov A. Goldstein | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 17.75 per share. | 06 Jun 2018 | 8,000 | 13,047 (0%) | 0% | 17.8 | 142,000 | Common Stock |
| Dov A. Goldstein | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2018 | 5,000 | 0 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2018 | 8,000 | 0 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Other type of transaction at price $ 0.00 per share. | 06 Jun 2018 | 8,000 | 47 (0%) | 0% | 0 | Common Stock | |
| Jay P. Shepard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 18,700 | 18,700 | - | - | Stock Option (right to buy) | |
| Antonio M. Gotto | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 10,100 | 10,100 | - | - | Stock Option (right to buy) | |
| Daniel S. Janney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 10,100 | 10,100 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 10,100 | 10,100 | - | - | Stock Option (right to buy) | |
| Mark E. McGovern | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 10,100 | 10,100 | - | - | Stock Option (right to buy) | |
| Roger Newton | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 10,100 | 10,100 | - | - | Stock Option (right tobuy) | |
| Nicole Vitullo | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 10,100 | 10,100 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Berkowitz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 4,427 | 4,427 | - | - | Stock Option (right to buy) | |
| Scott Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2018 | 10,100 | 10,100 | - | - | Stock Option (right to buy) | |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 72.31 per share. | 29 Mar 2018 | 8,656 | 631,026 (2%) | 0% | 72.3 | 625,915 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 71.36 per share. | 29 Mar 2018 | 7,100 | 623,926 (2%) | 0% | 71.4 | 506,656 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 70.71 per share. | 29 Mar 2018 | 200 | 623,726 (2%) | 0% | 70.7 | 14,142 | Common Stock |
| Roger Newton | None | Sale of securities on an exchange or to another person at price $ 73.26 per share. | 29 Mar 2018 | 9,044 | 639,682 (2%) | 0% | 73.3 | 662,563 | Common Stock |
| Daniel S. Janney | None | Other type of transaction at price $ 0.00 per share. | 28 Feb 2018 | 24,565 | 24,565 (0%) | 0% | 0 | Common Stock | |
| Daniel S. Janney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2018 | 4,967 | 4,967 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Berkowitz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Feb 2018 | 25,000 | 25,000 | - | - | Stock option (right to buy) | |
| Roger Newton | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2018 | 34,651 | 0 | - | - | Warrant to Purchase Common Stock | |
| Roger Newton | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.99 per share. | 07 Feb 2018 | 34,651 | 652,334 (2%) | 0% | 7.0 | 242,210 | Common Stock |
| Roger Newton | None | Gift of securities by or to the insider at price $ 0.00 per share. | 07 Feb 2018 | 12,000 | 617,683 (2%) | 0% | 0 | Common Stock | |
| Roger Newton | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.99 per share. | 07 Feb 2018 | 3,608 | 648,726 (2%) | 0% | 7.0 | 25,220 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2018 | 2,610 | 0 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.05 per share. | 31 Jan 2018 | 1,939 | 43,553 (0%) | 0% | 1.1 | 2,036 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.26 per share. | 31 Jan 2018 | 2,610 | 46,163 (0%) | 0% | 1.3 | 3,289 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2018 | 1,939 | 0 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 24 Jan 2018 | 645 | 3,177 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 24 Jan 2018 | 8,500 | 0 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Sale of securities on an exchange or to another person at price $ 71.79 per share. | 24 Jan 2018 | 11,674 | 15,329 (0%) | 0% | 71.8 | 838,076 | Common Stock |
| Nicole Vitullo | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 71.82 per share. | 24 Jan 2018 | 117 | 27,003 (0%) | 0% | 71.8 | 8,403 | Common Stock |
| Nicole Vitullo | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.99 per share. | 24 Jan 2018 | 1,193 | 27,120 (0%) | 0% | 7.0 | 8,339 | Common Stock |
| Nicole Vitullo | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 71.82 per share. | 24 Jan 2018 | 6,814 | 1,101,080 (4%) | 0% | 71.8 | 489,381 | Common Stock |
| Nicole Vitullo | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.99 per share. | 24 Jan 2018 | 70,042 | 1,107,894 (4%) | 0% | 7.0 | 489,594 | Common Stock |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 24 Jan 2018 | 8,500 | 8,500 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 24 Jan 2018 | 850,000 | 1,037,852 (3%) | 3% | 0 | Common Stock | |
| Nicole Vitullo | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2018 | 1,193 | 0 | - | - | Warrant to Purchase Common Stock | |
| Nicole Vitullo | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2018 | 70,042 | 0 | - | - | Warrant to Purchase Common Stock | |
| Daniel S. Janney | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 74.96 per share. | 18 Jan 2018 | 6,640 | 624,564 (2%) | 0% | 75.0 | 497,734 | Common Stock |
| Daniel S. Janney | None | Gift of securities by or to the insider at price $ 0.00 per share. | 18 Jan 2018 | 31,466 | 0 (0%) | 0% | 0 | Common Stock | |
| Daniel S. Janney | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jan 2018 | 71,237 | 0 | - | - | Warrant to Purchase Common Stock | |
| Daniel S. Janney | None | Gift of securities by or to the insider at price $ 0.00 per share. | 18 Jan 2018 | 7,020 | 0 (0%) | 0% | 0 | Common Stock | |
| Daniel S. Janney | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.99 per share. | 18 Jan 2018 | 71,237 | 631,204 (2%) | 0% | 7.0 | 497,947 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2018 | 107,000 | 107,000 | - | - | Stock Option (right to buy) | |
| Richard B. Bartram | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2018 | 17,892 | 0 | - | - | Stock Option (right to buy) | |
| Richard B. Bartram | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.70 per share. | 02 Jan 2018 | 17,892 | 19,092 (0%) | 0% | 3.7 | 66,200 | Common Stock |
| Richard B. Bartram | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2018 | 38,500 | 38,500 | - | - | Stock Option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2018 | 36,000 | 36,000 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Other type of transaction at price $ 0.00 per share. | 18 Dec 2017 | 21,471 | 47 (0%) | 0% | 0 | Common Stock | |
| Dov A. Goldstein | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2017 | 21,471 | 0 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.70 per share. | 18 Dec 2017 | 21,471 | 21,518 (0%) | 0% | 3.7 | 79,443 | Common Stock |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 06 Dec 2017 | 2,472 | 2,472 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 06 Dec 2017 | 329,083 | 1,887,852 (7%) | 1% | 0 | Common Stock | |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 06 Dec 2017 | 3,291 | 32,560 (0%) | 0% | 0 | Common Stock | |
| Nicole Vitullo | None | Sale of securities on an exchange or to another person at price $ 53.85 per share. | 06 Dec 2017 | 9,326 | 25,927 (0%) | 0% | 53.8 | 502,205 | Common Stock |
| Nicole Vitullo | None | Other type of transaction at price $ 0.00 per share. | 06 Dec 2017 | 32,560 | 0 (0%) | 0% | 0 | Common Stock | |
| Dov A. Goldstein | None | Other type of transaction at price $ 0.00 per share. | 05 Dec 2017 | 38 | 47 (0%) | 0% | 0 | Common Stock | |
| Antonio M. Gotto | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (right to buy) | |
| Daniel S. Janney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (right to buy) | |
| Gilbert S. Omenn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (right to buy) | |
| Mark E. McGovern | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (right to buy) | |
| Roger Newton | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Apr 2017 | 14,000 | 14,000 | - | - | Stock Option (right to buy) | |
| Daniel S. Janney | None | Sale of securities on an exchange or to another person at price $ 46.60 per share. | 21 Mar 2017 | 59,798 | 1,417,522 (6%) | 0% | 46.6 | 2,786,587 | Common Stock |
| Daniel S. Janney | None | Sale of securities on an exchange or to another person at price $ 47.54 per share. | 21 Mar 2017 | 56,855 | 1,360,667 (6%) | 0% | 47.5 | 2,702,887 | Common Stock |
| Daniel S. Janney | None | Sale of securities on an exchange or to another person at price $ 48.19 per share. | 21 Mar 2017 | 700 | 1,359,967 (6%) | 0% | 48.2 | 33,733 | Common Stock |
| Daniel S. Janney | None | Sale of securities on an exchange or to another person at price $ 45.43 per share. | 21 Mar 2017 | 111,307 | 1,477,320 (6%) | 0% | 45.4 | 5,056,677 | Common Stock |
| Daniel S. Janney | None | Sale of securities on an exchange or to another person at price $ 44.91 per share. | 21 Mar 2017 | 121,340 | 1,588,627 (7%) | 0% | 44.9 | 5,449,379 | Common Stock |
| Dov A. Goldstein | None | Sale of securities on an exchange or to another person at price $ 43.48 per share. | 21 Mar 2017 | 487,358 | 1,149,767 (5%) | 2% | 43.5 | 21,190,326 | Common Stock |
| Dov A. Goldstein | None | Sale of securities on an exchange or to another person at price $ 38.82 per share. | 21 Mar 2017 | 312,642 | 837,125 (3%) | 1% | 38.8 | 12,136,762 | Common Stock |
| Gilbert S. Omenn | None | Purchase of securities on an exchange or from another person at price $ 42.26 per share. | 21 Mar 2017 | 1,000 | 1,000 (0%) | 0% | 42.3 | 42,260 | Common Stock |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2017 | 171,100 | 171,100 | - | - | Stock Option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2017 | 10,800 | 10,800 | - | - | Stock Option (right to buy) | |
| Mary P. McGowan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Feb 2017 | 140,000 | 140,000 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2017 | 140,000 | 140,000 | - | - | Stock option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2017 | 55,000 | 55,000 | - | - | Stock Option (right to buy) | |
| Mary P. McGowan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2017 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Nov 2016 | 5,000 | 5,000 | - | - | Common Stock | |
| Mark E. McGovern | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Jul 2016 | 4,400 | 5,000 | - | - | Common Stock | |
| Mark E. McGovern | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Jul 2016 | 600 | 600 | - | - | Common Stock | |
| Antonio M. Gotto | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2016 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Daniel S. Janney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2016 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2016 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Gilbert S. Omenn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2016 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Mark E. McGovern | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2016 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2016 | 8,000 | 8,000 | - | - | Stock Option (Right to Buy) | |
| Scott Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2016 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 May 2016 | 7,000 | 41,614 | - | - | Common Stock | |
| Gilbert S. Omenn | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Mar 2016 | 5,000 | 10,000 | - | - | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Jan 2016 | 3,600 | 34,614 | - | - | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Jan 2016 | 7,200 | 31,014 | - | - | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 30,000 | 21 | - | - | Stock Option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Mary P. McGowan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Scott Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Aug 2015 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Mary P. McGowan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Aug 2015 | 210,000 | 210,000 | - | - | Stock Option (right to buy) | |
| Mary P. McGowan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Aug 2015 | 15,000 | 15,000 | - | - | Common Stock | |
| Antonio M. Gotto | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2015 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Daniel S. Janney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2015 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2015 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Gilbert S. Omenn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2015 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Mark E. McGovern | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2015 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Patrick G. Enright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2015 | 8,000 | 8,000 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2015 | 8,000 | 8,000 | - | - | Stock Option (Right to Buy) | |
| Dov A. Goldstein | None | Other type of transaction at price $ 0.00 per share. | 28 Apr 2015 | 199,991 | 1,637,125 | - | - | Common Stock | |
| Dov A. Goldstein | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Apr 2015 | 5,743 | 1,898,851 | - | - | Common Stock | |
| Dov A. Goldstein | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Apr 2015 | 150,000 | 1,904,594 | - | - | Common Stock | |
| Dov A. Goldstein | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Apr 2015 | 61,726 | 1,837,125 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 3,353 | 1,119,256 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 283,601 | 1,122,609 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 194,988 | 924,268 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 2,156 | 922,112 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 6,077 | 916,035 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 5,684 | 22,502 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 67 | 22,435 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 3,907 | 18,528 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 44 | 18,484 | - | - | Common Stock | |
| Patrick G. Enright | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 19 Mar 2015 | 123 | 18,361 | - | - | Common Stock | |
| Roger Newton | Director, Executive Chairman & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Mar 2015 | 8,000 | 8,000 | - | - | Stock option (right to buy) | |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Mar 2015 | 36,800 | 36,800 | - | - | Stock option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Mar 2015 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| Roger Newton | Director, Executive Chairman & CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 92,000 | 92,000 | - | - | Stock Option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2015 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2014 | 500 | 23,814 | - | - | Common Stock | |
| Timothy M. Mayleben | Director, President & CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2014 | 4,500 | 24,314 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 92 | 28,194 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 412 | 1,406,210 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 4,592 | 1,406,622 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 2,722 | 28,286 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 8 | 28,186 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 136,148 | 1,547,030 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 200,591 | 1,683,178 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 2,728 | 31,008 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 4,021 | 33,736 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 17 Nov 2014 | 135,816 | 1,411,214 | - | - | Common Stock | |
| Daniel S. Janney | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Oct 2014 | 500,000 | 2,552,189 | - | - | Common Stock | |
| Gilbert S. Omenn | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Oct 2014 | 5,000 | 5,000 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 09 Oct 2014 | 19 | 37,757 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 09 Oct 2014 | 924 | 1,883,769 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Oct 2014 | 235 | 37,776 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Oct 2014 | 11,692 | 1,884,693 | - | - | Common Stock | |
| Gilbert S. Omenn | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Aug 2014 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| Naredra D. Lalwani | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Aug 2014 | 250,000 | 250,000 | - | - | Stock Option (right to buy) | |
| Antonio M. Gotto | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2014 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Daniel S. Janney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2014 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Dov A. Goldstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2014 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Mark E. McGovern | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2014 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Patrick G. Enright | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2014 | 5,000 | 5,000 | - | - | Stock Option (right to buy) | |
| Nicole Vitullo | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2014 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| Mark E. McGovern | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2014 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Roger Newton | Director, Executive Chairman & C.S.O. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Dec 2013 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, Pres & Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Dec 2013 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Roger Newton | Director, Executive Chairman, CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2013 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Timothy M. Mayleben | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2013 | 190,000 | 190,000 | - | - | Stock Option (right to buy) | |
| Noah L. Rosenberg | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jul 2013 | 13,500 | 13,500 | - | - | Stock Option (right to buy) | |
| Brian K. Halak | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 4,791 | 35,253 | - | - | Common Stock | |
| Brian K. Halak | Ten Percent Owner | 01 Jul 2013 | 30,462 | 30,462 | - | - | Common Stock | ||
| Brian K. Halak | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 280,923 | 2,066,935 | - | - | Common Stock | |
| Brian K. Halak | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 1,786,012 | - | - | Common Stock | ||
| Brian K. Halak | Ten Percent Owner | 01 Jul 2013 | 30,462 | 0 | - | - | Series A Preferred Stock | ||
| Brian K. Halak | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 8,346 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Brian K. Halak | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 70,042 | 70,042 | - | - | Warrant to Purchase Common Stock | |
| Brian K. Halak | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 489,320 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Brian K. Halak | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 0 | - | - | Series A Preferred Stock | ||
| Brian K. Halak | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 1,193 | 1,193 | - | - | Warrant to Purchase Common Stock | |
| Brian H. Dovey | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 1,193 | 1,193 | - | - | Warrant to Purchase Common Stock | |
| Brian H. Dovey | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 4,791 | 35,253 | - | - | Common Stock | |
| Brian H. Dovey | Ten Percent Owner | 01 Jul 2013 | 30,462 | 30,462 | - | - | Common Stock | ||
| Brian H. Dovey | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 280,923 | 2,066,935 | - | - | Common Stock | |
| Brian H. Dovey | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 1,786,012 | - | - | Common Stock | ||
| Brian H. Dovey | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 0 | - | - | Series A Preferred Stock | ||
| Brian H. Dovey | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 489,320 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Brian H. Dovey | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 70,042 | 70,042 | - | - | Warrant to Purchase Common Stock | |
| Brian H. Dovey | Ten Percent Owner | 01 Jul 2013 | 30,462 | 0 | - | - | Series A Preferred Stock | ||
| Brian H. Dovey | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 8,346 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Daniel S. Janney | None | 01 Jul 2013 | 1,816,475 | 0 | - | - | Series A Preferred Stock | ||
| Daniel S. Janney | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 235,714 | 2,052,189 | - | - | Common Stock | |
| Daniel S. Janney | None | 01 Jul 2013 | 1,816,475 | 1,816,475 | - | - | Common Stock | ||
| Daniel S. Janney | None | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 497,666 | 0 | - | - | Warrant to Purchase Preferred Stock | |
| Daniel S. Janney | None | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 71,237 | 71,237 | - | - | Warrant to Purchase Common Stock | |
| Dov A. Goldstein | None | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 71,237 | 71,237 | - | - | Warrant to Purchase Common Stock | |
| Dov A. Goldstein | None | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 497,666 | 0 | - | - | Warrant to Purchase Preferred Stock | |
| Dov A. Goldstein | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 238,119 | 2,054,594 | - | - | Common Stock | |
| Dov A. Goldstein | None | 01 Jul 2013 | 1,816,475 | 1,816,475 | - | - | Common Stock | ||
| Dov A. Goldstein | None | 01 Jul 2013 | 1,816,475 | 0 | - | - | Series A Preferred Stock | ||
| James C. Blair | Ten Percent Owner | 01 Jul 2013 | 30,462 | 0 | - | - | Series A Preferred Stock | ||
| James C. Blair | Ten Percent Owner | 01 Jul 2013 | 30,462 | 30,462 | - | - | Common Stock | ||
| James C. Blair | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 280,923 | 2,066,935 | - | - | Common Stock | |
| James C. Blair | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 1,786,012 | - | - | Common Stock | ||
| James C. Blair | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 1,193 | 1,193 | - | - | Warrant to Purchase Common Stock | |
| James C. Blair | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 8,346 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| James C. Blair | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 4,791 | 35,253 | - | - | Common Stock | |
| James C. Blair | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 70,042 | 70,042 | - | - | Warrant to Purchase Common Stock | |
| James C. Blair | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 489,320 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| James C. Blair | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 0 | - | - | Series A Preferred Stock | ||
| Jesse I. Treu | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 70,042 | 70,042 | - | - | Warrant to Purchase Common Stock | |
| Jesse I. Treu | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 0 | - | - | Series A Preferred Stock | ||
| Jesse I. Treu | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 489,320 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Jesse I. Treu | Ten Percent Owner | 01 Jul 2013 | 30,462 | 0 | - | - | Series A Preferred Stock | ||
| Jesse I. Treu | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 8,346 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Jesse I. Treu | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 1,193 | 1,193 | - | - | Warrant to Purchase Common Stock | |
| Jesse I. Treu | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 1,786,012 | - | - | Common Stock | ||
| Jesse I. Treu | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 280,923 | 2,066,935 | - | - | Common Stock | |
| Jesse I. Treu | Ten Percent Owner | 01 Jul 2013 | 30,462 | 30,462 | - | - | Common Stock | ||
| Jesse I. Treu | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 4,791 | 35,253 | - | - | Common Stock | |
| Louis G. Lange | None | 01 Jul 2013 | 14,314 | 0 | - | - | Series A Preferred Stock | ||
| Louis G. Lange | None | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 51,230 | 0 | - | - | Warrant to Purchase Preferred Stock | |
| Louis G. Lange | None | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 7,333 | 7,333 | - | - | Warrant to Purchase Common Stock | |
| Louis G. Lange | None | 01 Jul 2013 | 186,989 | 186,989 | - | - | Common Stock | ||
| Louis G. Lange | None | 01 Jul 2013 | 14,314 | 14,314 | - | - | Common Stock | ||
| Louis G. Lange | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 3,500 | 17,814 | - | - | Common Stock | |
| Louis G. Lange | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 10,714 | 197,703 | - | - | Common Stock | |
| Louis G. Lange | None | 01 Jul 2013 | 186,989 | 0 | - | - | Series A Preferred Stock | ||
| Patrick G. Enright | Director, Ten Percent Owner | 01 Jul 2013 | 1,683,967 | 1,683,967 | - | - | Common Stock | ||
| Patrick G. Enright | Director, Ten Percent Owner | 01 Jul 2013 | 33,753 | 33,753 | - | - | Common Stock | ||
| Patrick G. Enright | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 212,418 | 1,896,385 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 4,258 | 38,011 | - | - | Common Stock | |
| Patrick G. Enright | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2013 | 21,471 | 21,471 | - | - | Stock Option (right to buy) | |
| Patrick G. Enright | Director, Ten Percent Owner | 01 Jul 2013 | 33,753 | 0 | - | - | Series A Preferred Stock | ||
| Patrick G. Enright | Director, Ten Percent Owner | 01 Jul 2013 | 1,683,967 | 0 | - | - | Series A Preferred Stock | ||
| Roger Newton | Director, Executive Chairman, CSO | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 34,651 | 34,651 | - | - | Warrant to Purchase Common Stock | |
| Roger Newton | Director, Executive Chairman, CSO | 01 Jul 2013 | 301,051 | 0 | - | - | Series A Preferred Stock | ||
| Roger Newton | Director, Executive Chairman, CSO | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 242,082 | 0 | - | - | Warrant to Purchase Preferred Stock | |
| Roger Newton | Director, Executive Chairman, CSO | 01 Jul 2013 | 301,051 | 587,337 | - | - | Common Stock | ||
| Roger Newton | Director, Executive Chairman, CSO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 42,346 | 629,683 | - | - | Common Stock | |
| Timothy M. Mayleben | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 5,000 | 28,814 | - | - | Common Stock | |
| Nicole Vitullo | Director, Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 0 | - | - | Series A Preferred Stock | ||
| Nicole Vitullo | Director, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 1,193 | 1,193 | - | - | Warrant to Purchase Common Stock | |
| Nicole Vitullo | Director, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 8,346 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Nicole Vitullo | Director, Ten Percent Owner | 01 Jul 2013 | 30,462 | 0 | - | - | Series A Preferred Stock | ||
| Nicole Vitullo | Director, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 70,042 | 70,042 | - | - | Warrant to Purchase Common Stock | |
| Nicole Vitullo | Director, Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 1,786,012 | - | - | Common Stock | ||
| Nicole Vitullo | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 280,923 | 2,066,935 | - | - | Common Stock | |
| Nicole Vitullo | Director, Ten Percent Owner | 01 Jul 2013 | 30,462 | 30,462 | - | - | Common Stock | ||
| Nicole Vitullo | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 4,791 | 35,253 | - | - | Common Stock | |
| Nicole Vitullo | Director, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 489,320 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Schoemaker K Kathleen | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 489,320 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Schoemaker K Kathleen | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 4,791 | 35,253 | - | - | Common Stock | |
| Schoemaker K Kathleen | Ten Percent Owner | 01 Jul 2013 | 30,462 | 30,462 | - | - | Common Stock | ||
| Schoemaker K Kathleen | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 01 Jul 2013 | 280,923 | 2,066,935 | - | - | Common Stock | |
| Schoemaker K Kathleen | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 1,786,012 | - | - | Common Stock | ||
| Schoemaker K Kathleen | Ten Percent Owner | 01 Jul 2013 | 1,786,012 | 0 | - | - | Series A Preferred Stock | ||
| Schoemaker K Kathleen | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 1,193 | 1,193 | - | - | Warrant to Purchase Common Stock | |
| Schoemaker K Kathleen | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 8,346 | 0 | - | - | Warrant to Purchase Series A Preferred Stock | |
| Schoemaker K Kathleen | Ten Percent Owner | 01 Jul 2013 | 30,462 | 0 | - | - | Series A Preferred Stock | ||
| Schoemaker K Kathleen | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2013 | 70,042 | 70,042 | - | - | Warrant to Purchase Common Stock |