Market Cap
Low in industry
PE TTM
Negative PE TTM
PEG TTM
Price to Book
Negative Price to Book
Beta 1Year
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Steven D. Rubin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,750 | 15,750 (0%) | 0% | 0 | Common Stock | |
| Steven D. Rubin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,750 | 3,750 | - | - | Restricted Stock Units | |
| Sumit Aggarwal | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 30,000 | 199,930 (0%) | 0% | 0 | Common Stock | |
| Sumit Aggarwal | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 30,000 | 30,000 | - | - | Restricted Stock Units | |
| Alan Walts | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,750 | 3,750 | - | - | Restricted Stock Units | |
| Alan Walts | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,750 | 16,692 (0%) | 0% | 0 | Common Stock | |
| Lindsay Androski | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,750 | 15,750 (0%) | 0% | 0 | Common Stock | |
| Lindsay Androski | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jan 2025 | 3,750 | 3,750 | - | - | Restricted Stock Units | |
| Androski Lindsay | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Oct 2024 | 12,000 | 12,000 (0%) | 0% | 0 | Common Stock | |
| Walts Alan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Oct 2024 | 12,000 | 12,942 (0%) | 0% | 0 | Common Stock | |
| Aggarwal Sumit | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Oct 2024 | 165,000 | 169,930 (0%) | 0% | 0 | Common Stock | |
| D. Steven Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Oct 2024 | 12,000 | 12,000 (0%) | 0% | 0 | Common Stock | |
| Lindsay Androski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 7,500 | 7,500 | - | - | Restricted Stock Units | |
| Aggarwal Sumit | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 60,000 | 60,000 | - | - | Restricted Stock Units | |
| D. Rubin Steven | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 7,500 | 7,500 | - | - | Restricted Stock Units | |
| Alan Walts | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jan 2024 | 7,500 | 7,500 | - | - | Restricted Stock Units | |
| Steven D. Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2023 | 2,859 | 2,859 | - | - | Stock Options (Right to Buy) | |
| Tomer Kariv | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2023 | 2,859 | 2,859 | - | - | Stock Options (Right to Buy) | |
| Alan Walts | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2023 | 2,859 | 2,859 | - | - | Stock Options (Right to Buy) | |
| Lindsay Androski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2023 | 2,859 | 2,859 | - | - | Stock Options (Right to Buy) | |
| Vijay Modur | HEAD OF R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2023 | 30,000 | 30,000 | - | - | Stock Options (Right to Buy) | |
| Sumit Aggarwal | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2023 | 68,700 | 68,700 | - | - | Stock Options (Right to Buy) | |
| Lindsay Androski | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 40,000 | 40,000 | - | - | Stock Options (Right to Buy) | |
| Steven D. Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Rajesh B. Parekh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Tomer Kariv | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Ran Nussbaum | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Gadi Veinrib | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Zafrira Avnur | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Jasbir Seehra | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Alan Walts | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 20,000 | 20,000 | - | - | Stock Options (Right to Buy) | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 May 2021 | 6,250 | 68,750 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.39 per share. | 25 May 2021 | 1,835 | 31,595 (0%) | 0% | 1.4 | 2,551 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 May 2021 | 6,250 | 33,430 (0%) | 0% | 0 | Common Stock | |
| Steven D. Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2021 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Tomer Kariv | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2021 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Ran Nussbaum | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2021 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Gadi Veinrib | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2021 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Zafrira Avnur | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2021 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Jasbir Seehra | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2021 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Alan Walts | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2021 | 3,334 | 3,334 | - | - | Stock Option (Right to Buy) | |
| Vijay Modur | HEAD OF R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 496,204 | 496,204 | - | - | Stock Options (Right to Buy) | |
| Sumit Aggarwal | Director, PRESIDENT AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2021 | 992,409 | 992,409 | - | - | Stock Options (Right to Buy) | |
| Tomer Kariv | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 1,280,624 | 1,791,470 (4%) | 3% | 1.3 | 1,728,842 | Common Stock |
| Tomer Kariv | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 2,630,487 | 3,679,797 (9%) | 6% | 1.3 | 3,551,157 | Common Stock |
| Tomer Kariv | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 1,422,222 | 1,989,551 (4%) | 3% | 1.4 | 1,920,000 | Common Stock |
| Tomer Kariv | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 592,592 | 616,592 (1%) | 1% | 1.3 | 799,999 | Common Stock |
| Ran Nussbaum | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 2,630,487 | 3,679,797 (9%) | 6% | 1.3 | 3,551,157 | Common Stock |
| Ran Nussbaum | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 1,280,624 | 1,791,470 (4%) | 3% | 1.3 | 1,728,842 | Common Stock |
| Ran Nussbaum | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 592,592 | 616,592 (1%) | 1% | 1.3 | 799,999 | Common Stock |
| Ran Nussbaum | Director | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 13 May 2021 | 1,422,222 | 1,989,551 (4%) | 3% | 1.4 | 1,920,000 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2021 | 1,562 | 27,639 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.18 per share. | 30 Apr 2021 | 459 | 27,180 (0%) | 0% | 2.2 | 1,001 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2021 | 1,562 | 10,938 | - | - | Restricted Stock Units | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2021 | 50,000 | 59,989 (0%) | 0% | 0 | Common Stock | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2021 | 50,000 | 150,000 | - | - | Restricted Stock Units | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.95 per share. | 25 Feb 2021 | 15,360 | 44,629 (0%) | 0% | 4.0 | 60,672 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2021 | 25,000 | 75,000 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.95 per share. | 25 Feb 2021 | 7,338 | 26,077 (0%) | 0% | 3.9 | 28,985 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2021 | 25,000 | 33,415 (0%) | 0% | 0 | Common Stock | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 300,000 | 300,000 | - | - | Stock Options | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 120,000 | 120,000 | - | - | Stock Options | |
| Stephen MacDonald | VP FINANCE & ACCTG, TREASURER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2021 | 18,849 | 18,849 | - | - | Stock Options | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2021 | 1,875 | 15,000 | - | - | Restricted Stock Units | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2021 | 1,875 | 10,632 (0%) | 0% | 0 | Common Stock | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.44 per share. | 30 Jan 2021 | 643 | 9,989 (0%) | 0% | 3.4 | 2,212 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2021 | 1,563 | 8,957 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2021 | 1,563 | 12,500 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.44 per share. | 30 Jan 2021 | 542 | 8,415 (0%) | 0% | 3.4 | 1,864 | Common Stock |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Oct 2020 | 1,875 | 16,875 | - | - | Restricted Stock Units | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.53 per share. | 30 Oct 2020 | 625 | 8,757 (0%) | 0% | 2.5 | 1,581 | Common Stock |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Oct 2020 | 1,875 | 9,382 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Oct 2020 | 1,562 | 7,853 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Oct 2020 | 1,562 | 14,063 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.53 per share. | 30 Oct 2020 | 459 | 7,394 (0%) | 0% | 2.5 | 1,161 | Common Stock |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.84 per share. | 30 Jul 2020 | 576 | 7,507 (0%) | 0% | 2.8 | 1,636 | Common Stock |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jul 2020 | 1,875 | 18,750 | - | - | Restricted Stock Units | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jul 2020 | 1,875 | 8,083 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jul 2020 | 1,563 | 6,750 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jul 2020 | 1,563 | 15,625 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.84 per share. | 30 Jul 2020 | 459 | 6,291 (0%) | 0% | 2.8 | 1,304 | Common Stock |
| Silvia Noiman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Steven D. Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Tomer Kariv | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Martijn Kleijwegt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Ran Nussbaum | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Gadi Veinrib | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Zafrira Avnur | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Jasbir Seehra | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.92 per share. | 30 Apr 2020 | 577 | 6,208 (0%) | 0% | 2.9 | 1,685 | Common Stock |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2020 | 1,875 | 20,625 | - | - | Restricted Stock Units | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2020 | 1,875 | 6,785 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2020 | 1,562 | 5,646 (0%) | 0% | 0 | Common Stock | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.92 per share. | 30 Apr 2020 | 459 | 5,187 (0%) | 0% | 2.9 | 1,340 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2020 | 1,562 | 17,188 | - | - | Restricted Stock Units | |
| Gregory L. Weaver | FORMER CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2020 | 3,750 | 11,517 (0%) | 0% | 0 | Common Stock | |
| Gregory L. Weaver | FORMER CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2020 | 3,750 | 0 | - | - | Restricted Stock Units | |
| Gregory L. Weaver | FORMER CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.85 per share. | 15 Mar 2020 | 1,086 | 10,431 (0%) | 0% | 2.8 | 3,095 | Common Stock |
| Robert E. Ward | FORMER CHAIRMAN AND CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Feb 2020 | 71,199 | 0 | - | - | Restricted Stock Units | |
| Robert E. Ward | FORMER CHAIRMAN AND CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Feb 2020 | 5,607 | 0 | - | - | Restricted Stock Units | |
| Robert E. Ward | FORMER CHAIRMAN AND CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Feb 2020 | 76,806 | 267,552 (0%) | 0% | 0 | Common Stock | |
| Robert E. Ward | FORMER CHAIRMAN AND CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.13 per share. | 29 Feb 2020 | 23,285 | 244,267 (0%) | 0% | 3.1 | 72,882 | Common Stock |
| David P. Snow | FORMER CHIEF BUSINESS OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Feb 2020 | 4,688 | 8,893 (0%) | 0% | 0 | Common Stock | |
| David P. Snow | FORMER CHIEF BUSINESS OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.13 per share. | 29 Feb 2020 | 1,534 | 7,359 (0%) | 0% | 3.1 | 4,801 | Common Stock |
| David P. Snow | FORMER CHIEF BUSINESS OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Feb 2020 | 4,688 | 0 | - | - | Restricted Stock Units | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 400,000 | 400,000 | - | - | Stock Options | |
| Gregory Williams | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 200,000 | 200,000 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 200,000 | 200,000 | - | - | Stock Options | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 100,000 | 100,000 | - | - | Restricted Stock Units | |
| Gregory L. Weaver | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 5,000 | 15,000 | - | - | Restricted Stock Units | |
| Gregory L. Weaver | CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.91 per share. | 30 Jan 2020 | 1,733 | 7,767 (0%) | 0% | 3.9 | 6,776 | Common Stock |
| Gregory L. Weaver | CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 5,000 | 9,500 (0%) | 0% | 0 | Common Stock | |
| Gregory Williams | Other, FORMER CHIEF OPERATING OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 7,500 | 7,500 (0%) | 0% | 0 | Common Stock | |
| Gregory Williams | Other, FORMER CHIEF OPERATING OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.91 per share. | 30 Jan 2020 | 2,590 | 4,910 (0%) | 0% | 3.9 | 10,127 | Common Stock |
| Gregory Williams | Other, FORMER CHIEF OPERATING OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 7,500 | 22,500 | - | - | Restricted Stock Units | |
| David P. Snow | FORMER CHIEF BUSINESS OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.91 per share. | 30 Jan 2020 | 2,045 | 4,205 (0%) | 0% | 3.9 | 7,996 | Common Stock |
| David P. Snow | FORMER CHIEF BUSINESS OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 6,250 | 6,250 (0%) | 0% | 0 | Common Stock | |
| David P. Snow | FORMER CHIEF BUSINESS OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 6,250 | 18,750 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 6,250 | 18,750 | - | - | Restricted Stock Units | |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.91 per share. | 30 Jan 2020 | 2,166 | 4,084 (0%) | 0% | 3.9 | 8,469 | Common Stock |
| Neil S. Belloff | COO, GENERAL COUNSEL &CORP SEC | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2020 | 6,250 | 6,250 (0%) | 0% | 0 | Common Stock | |
| Robert E. Ward | Director, CHAIRMAN AND CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.26 per share. | 26 Dec 2019 | 15,806 | 190,746 (0%) | 0% | 7.3 | 114,752 | Common Stock |
| Robert E. Ward | Director, CHAIRMAN AND CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Dec 2019 | 35,599 | 206,552 (0%) | 0% | 0 | Common Stock | |
| Robert E. Ward | Director, CHAIRMAN AND CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Dec 2019 | 35,599 | 284,794 | - | - | Restricted Stock Units | |
| Robert E. Ward | Director, CHAIRMAN AND CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Sep 2019 | 35,599 | 181,420 (0%) | 0% | 0 | Common Stock | |
| Robert E. Ward | Director, CHAIRMAN AND CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Sep 2019 | 35,599 | 320,393 | - | - | Restricted Stock Units | |
| Robert E. Ward | Director, CHAIRMAN AND CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.37 per share. | 26 Sep 2019 | 10,467 | 170,953 (0%) | 0% | 4.4 | 45,741 | Common Stock |
| Gregory Williams | CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 225,000 | 225,000 | - | - | Employee Stock Option (Right to Buy) | |
| David P. Snow | CHIEF BUSINESS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 150,000 | 150,000 | - | - | Employee Stock Option (Right to Buy) | |
| Neil S. Belloff | GENERAL COUNSEL/CORPORATE SECR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Sep 2019 | 100,000 | 100,000 | - | - | Employee Stock Option (Right to Buy) | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jun 2019 | 35,599 | 156,288 (0%) | 0% | 0 | Common Stock | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jun 2019 | 35,599 | 355,992 | - | - | Restricted Stock Units | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 9.03 per share. | 26 Jun 2019 | 10,467 | 145,821 (0%) | 0% | 9.0 | 94,517 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 24,000 | 24,000 (0%) | 0% | 9 | 216,000 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 46,933 | 567,329 (1%) | 0% | 9 | 422,397 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 42,261 | 510,846 (1%) | 0% | 9 | 380,349 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 86,806 | 1,049,310 (2%) | 0% | 9 | 781,254 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 24,000 | 24,000 (0%) | 0% | 9 | 216,000 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 42,261 | 510,846 (1%) | 0% | 9 | 380,349 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 86,806 | 1,049,310 (2%) | 0% | 9 | 781,254 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 9.00 per share. | 24 Jun 2019 | 46,933 | 567,329 (1%) | 0% | 9 | 422,397 | Common Stock |
| Silvia Noiman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Martijn Kleijwegt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Ran Nussbaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Zafrira Avnur | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Jasbir Seehra | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 11.50 per share. | 26 Mar 2019 | 10,467 | 120,689 (0%) | 0% | 11.5 | 120,371 | Common Stock |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Mar 2019 | 35,599 | 391,591 | - | - | Restricted Stock Units | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Mar 2019 | 35,599 | 131,156 (0%) | 0% | 0 | Common Stock | |
| Gregory L. Weaver | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 60,000 | 60,000 | - | - | Stock Options | |
| Gregory L. Weaver | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 20,000 | 20,000 | - | - | Restricted Stock Units | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 226,000 | 226,000 | - | - | Stock Options | |
| Gregory Williams | CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 30,000 | 30,000 | - | - | Restricted Stock Units | |
| Gregory Williams | CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 100,000 | 100,000 | - | - | Stock Options | |
| David P. Snow | CHIEF BUSINESS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 55,000 | 55,000 | - | - | Stock Options | |
| David P. Snow | CHIEF BUSINESS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 25,000 | 25,000 | - | - | Restricted Stock Units | |
| Neil S. Belloff | GENERAL COUNSEL/CORPORATE SECR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 25,000 | 25,000 | - | - | Restricted Stock Units | |
| Neil S. Belloff | GENERAL COUNSEL/CORPORATE SECR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jan 2019 | 50,000 | 50,000 | - | - | Stock Options | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.60 per share. | 26 Dec 2018 | 83,038 | 145,557 (0%) | 0% | 12.6 | 1,046,279 | Common Stock |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Gift of securities by or to the insider at price $ 0.00 per share. | 26 Dec 2018 | 50,000 | 95,557 (0%) | 0% | 0 | Common Stock | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Dec 2018 | 213,595 | 427,190 | - | - | Restricted Stock Units | |
| Robert E. Ward | Director, CHIEF EXECUTIVE OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Dec 2018 | 213,595 | 228,595 (0%) | 0% | 0 | Common Stock | |
| Gregory Williams | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2018 | 300,000 | 300,000 | - | - | Employee Stock Option (Right to Buy) | |
| David P. Snow | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2018 | 200,000 | 200,000 | - | - | Employee Stock Option (Right to Buy) | |
| Neil S. Belloff | General Counsel and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2018 | 125,000 | 125,000 | - | - | Employee Stock Option (Right to Buy) | |
| Silvia Noiman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 141,389 | 141,389 (0%) | 0% | 0 | Common Stock | |
| Silvia Noiman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Employee Stock Option (Right to Buy) | |
| Silvia Noiman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 141,389 | 141,389 | - | - | Employee Stock Option (Right to Buy) | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Tomer Kariv | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Martijn Kleijwegt | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Ran Nussbaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Gadi Veinrib | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Zafrira Avnur | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Jasbir Seehra | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Silvia Noiman | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2018 | 349,400 | 490,789 (1%) | 1% | 0.0 | 210 | Common Stock |
| Silvia Noiman | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2018 | 349,400 | 0 | - | - | Stock Option (Right to Buy) | |
| Robert E. Ward | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 14.34 per share. | 22 May 2018 | 5,000 | 15,000 (0%) | 0% | 14.3 | 71,700 | Common Stock |
| Pedro Huertas | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2018 | 33,000 | 137,725 (0%) | 0% | 0 | Common Stock | |
| Pedro Huertas | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2018 | 104,725 | 104,725 | - | - | Employee Stock Option (Right to Buy) | |
| Pedro Huertas | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2018 | 104,725 | 104,725 (0%) | 0% | 0 | Common Stock | |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 30 Apr 2018 | 84,041 | 468,585 (1%) | 0% | 9.8 | 819,400 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 30 Apr 2018 | 172,626 | 962,504 (2%) | 0% | 9.8 | 1,683,104 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 30 Apr 2018 | 93,333 | 520,396 (1%) | 0% | 9.8 | 909,997 | Common Stock |
| Martijn Kleijwegt | None | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 30 Apr 2018 | 300,000 | 2,953,673 (8%) | 0% | 9.8 | 2,925,000 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 30 Apr 2018 | 93,333 | 520,396 (1%) | 0% | 9.8 | 909,997 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 30 Apr 2018 | 172,626 | 962,504 (2%) | 0% | 9.8 | 1,683,104 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 30 Apr 2018 | 84,041 | 468,585 (1%) | 0% | 9.8 | 819,400 | Common Stock |
| Zafrira Avnur | None | Purchase of securities on an exchange or from another person at price $ 9.49 per share. | 26 Mar 2018 | 2,000 | 2,263 (0%) | 0% | 9.5 | 18,980 | Common Stock |
| Gregory L. Weaver | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 8.56 per share. | 23 Mar 2018 | 4,500 | 4,500 (0%) | 0% | 8.6 | 38,520 | Common Stock |
| Robert E. Ward | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 8.99 per share. | 23 Mar 2018 | 10,000 | 10,000 (0%) | 0% | 9.0 | 89,900 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 7.55 per share. | 21 Mar 2018 | 1,760 | 425,463 (1%) | 0% | 7.6 | 13,288 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 7.55 per share. | 21 Mar 2018 | 1,585 | 383,103 (1%) | 0% | 7.6 | 11,967 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 21 Mar 2018 | 1,441 | 384,544 (1%) | 0% | 8 | 11,528 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 21 Mar 2018 | 2,959 | 789,878 (2%) | 0% | 8 | 23,672 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 21 Mar 2018 | 1,600 | 427,063 (1%) | 0% | 8 | 12,800 | Common Stock |
| Tomer Kariv | None | Purchase of securities on an exchange or from another person at price $ 7.55 per share. | 21 Mar 2018 | 3,255 | 786,919 (2%) | 0% | 7.5 | 24,575 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 7.55 per share. | 21 Mar 2018 | 3,255 | 786,919 (2%) | 0% | 7.5 | 24,575 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 7.55 per share. | 21 Mar 2018 | 1,585 | 383,103 (1%) | 0% | 7.6 | 11,967 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 21 Mar 2018 | 1,441 | 384,544 (1%) | 0% | 8 | 11,528 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 21 Mar 2018 | 1,600 | 427,063 (1%) | 0% | 8 | 12,800 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 7.55 per share. | 21 Mar 2018 | 1,760 | 425,463 (1%) | 0% | 7.6 | 13,288 | Common Stock |
| Ran Nussbaum | None | Purchase of securities on an exchange or from another person at price $ 8.00 per share. | 21 Mar 2018 | 2,959 | 789,878 (2%) | 0% | 8 | 23,672 | Common Stock |
| Zafrira Avnur | None | Purchase of securities on an exchange or from another person at price $ 7.60 per share. | 21 Mar 2018 | 263 | 263 (0%) | 0% | 7.6 | 1,999 | Common Stock |
| Pedro Huertas | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2018 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Robert E. Ward | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Dec 2017 | 22,427 | 22,427 | - | - | Stock Options (Right to Buy) | |
| Robert E. Ward | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Dec 2017 | 22,427 | 22,427 | - | - | Restricted Stock Units | |
| Robert E. Ward | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Dec 2017 | 640,785 | 640,785 | - | - | Stock Options (Right to Buy) | |
| Robert E. Ward | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Dec 2017 | 640,785 | 640,785 | - | - | Restricted Stock Units | |
| Gregory L. Weaver | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Dec 2017 | 399,266 | 399,266 | - | - | Employee Stock Option (Right to Buy) | |
| David S. Rector | Other | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2017 | 27,500 | 27,500 | - | - | Common Stock Option (Right to Buy) | |
| Phillip Frost | Other | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2017 | 3,621 | 3,621 | - | - | Company Stock Option | |
| John N. Braca | Other | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2017 | 18,190 | 18,190 | - | - | Company Stock Option | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2017 | 43,189 | 43,189 | - | - | Common Stock Option (Right to Buy) | |
| Phillip Frost | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2017 | 109,091 | 109,091 | - | - | Company Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2017 | 167,045 | 167,045 | - | - | Company Stock Option | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2017 | 160,227 | 160,227 | - | - | Company Stock Option | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2016 | 78,409 | 78,409 | - | - | Company Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2016 | 89,773 | 89,773 | - | - | Company Stock Option | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2016 | 89,773 | 89,773 | - | - | Company Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2015 | 40,000 | 40,000 | - | - | Company Stock Option | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2015 | 32,500 | 32,500 | - | - | Company Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2015 | 42,500 | 42,500 | - | - | Company Stock Option | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2015 | 40,000 | 40,000 | - | - | Company Stock Option | |
| Phillip Frost | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Sep 2015 | 35,000 | 1,598,170 | - | - | Common Stock | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2015 | 11,340 | 147,693 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2015 | 26,552 | 136,353 | - | - | Common Stock Option | |
| Joel Brooks | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 28,140 | 47,300 | - | - | Common Stock Option (right to buy) | |
| John E. Thompson | Scientific Founder | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 34,020 | 53,391 | - | - | Common Stock Option (right to buy) | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 5,270 | 77,914 | - | - | Common Stock Option (right to buy) | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 31,698 | 72,644 | - | - | Common Stock Option (right to buy) | |
| Richard Dondero | VP - Preclinical Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 28,140 | 49,476 | - | - | Common Stock Option (right to buy) | |
| Leslie J. Browne | President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 42,210 | 82,065 | - | - | Common Stock Option (right to buy) | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 3,314 | 28,658 | - | - | Common Stock Option (right to buy) | |
| Steven D. Rubin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 25,344 | 25,344 | - | - | Common Stock Option (right to buy) | |
| Vaughn Smider | Director, Chief Scientific Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 42,210 | 42,210 | - | - | Common Stock Option (right to buy) | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 28,140 | 28,140 | - | - | Common Stock Option (right to buy) | |
| Miguel de los Rios | VP - Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 34,020 | 147,102 | - | - | Common Stock Option (right to buy) | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 5,270 | 78,650 | - | - | Common Stock Option (right to buy) | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 31,698 | 73,380 | - | - | Common Stock Option (right to buy) | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 38,034 | 92,332 | - | - | Common Stock Option (right to buy) | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 17,168 | 109,500 | - | - | Common Stock Option (right to buy) | |
| Ronald A. Martell | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 56,364 | 456,364 | - | - | Common Stock Option (right to buy) | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 25,344 | 25,344 | - | - | Common Stock Option (right to buy) | |
| Christopher Forbes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 27,882 | 64,107 | - | - | Common Stock Option (right to buy) | |
| Christopher Forbes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2014 | 3,462 | 67,569 | - | - | Common Stock Option (right to buy) | |
| Ronald A. Martell | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2014 | 400,000 | 400,000 | - | - | Employee Stock Option | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2014 | 211,626 | 211,626 | - | - | Series FA Warrants | |
| Phillip Frost | Director, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 13 Jun 2014 | 211,626 | 0 | - | - | Series FA Warrants | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2014 | 333,333 | 333,333 | - | - | Series A Warrants | |
| Phillip Frost | Director, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 0.00 per share. | 13 Jun 2014 | 333,333 | 0 | - | - | Series A Warrants | |
| Vaughn Smider | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2014 | 242,563 | 242,563 | - | - | Series FA Warrants | |
| Vaughn Smider | Director, See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2014 | 7,411 | 249,974 | - | - | Series FA Warrants | |
| Vaughn Smider | Director, See Remarks | Sale or transfer of securities back to the company at price $ 0.00 per share. | 13 Jun 2014 | 7,411 | 0 | - | - | Series FA Warrants | |
| Vaughn Smider | Director, See Remarks | Sale or transfer of securities back to the company at price $ 0.00 per share. | 13 Jun 2014 | 242,563 | 7,411 | - | - | Series FA Warrants | |
| James Graziano | Chief Technology Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 13 Jun 2014 | 24,641 | 0 | - | - | Series FA Warrants | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2014 | 24,641 | 24,641 | - | - | Series FA Warrants | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 7,500 | 43,056 | - | - | Common Stock Option | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 211,626 | 544,959 | - | - | Warrant | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 11,688 | 11,688 | - | - | Warrant | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 646 | 646 | - | - | Warrant | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 6,927 | 6,927 | - | - | Warrant | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 896,504 | 1,563,170 | - | - | Common Stock | |
| Phillip Frost | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 233,696 | 567,029 | - | - | Warrant | |
| Rudolf Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 7,500 | 52,405 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 5,000 | 13,149 | - | - | Common Stock | |
| Warren J. Isabelle | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 5,000 | 6,038 | - | - | Common Stock | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 13,394 | 13,394 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 31,396 | 1,058,970 | - | - | Common Stock | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 410 | 13,804 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 7,411 | 249,974 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 1,027,574 | 1,058,970 | - | - | Common Stock | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 244 | 8,180 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 739 | 739 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 267,862 | 267,862 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 7,936 | 7,936 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 23 | 762 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 8,185 | 276,047 | - | - | Warrants | |
| Vaughn Smider | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 242,563 | 242,563 | - | - | Warrants | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 1,361 | 1,361 | - | - | Warrant | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 24,641 | 24,641 | - | - | Warrant | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 104,386 | 104,386 | - | - | Common Stock | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 807 | 807 | - | - | Warrant | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 27,211 | 27,211 | - | - | Warrant | |
| James Graziano | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 76 | 76 | - | - | Warrant | |
| Miguel de los Rios | VP- Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2014 | 113,082 | 113,082 | - | - | Common Stock Option | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 21,074 | 41,682 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 16,788 | 35,556 | - | - | Common Stock Options | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 21,932 | 54,298 | - | - | Common Stock Option | |
| Christopher Forbes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 17,464 | 36,406 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 21,074 | 40,946 | - | - | Common Stock Option | |
| Rudolf Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 20,306 | 44,905 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2014 | 10,560 | 26,738 | - | - | Common Stock Options | |
| Leslie J. Browne | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Dec 2013 | 800 | 1,290 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 371,000 | 2,080,765 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 265,000 | 1,876,761 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 530,000 | 3,236,572 | - | - | Common Stock Option | |
| Christopher Forbes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 318,000 | 2,002,193 | - | - | Common Stock Option | |
| Joel Brooks | CFO, Secretary, Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 985,000 | 2,177,200 | - | - | Common Stock Option | |
| John E. Thompson | Director, Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 985,000 | 2,203,276 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 371,000 | 1,992,215 | - | - | Common Stock Option | |
| Rudolf Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 265,000 | 2,479,851 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 265,000 | 1,637,763 | - | - | Common Stock Option | |
| Richard Dondero | VP Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 985,000 | 2,360,124 | - | - | Common Stock Option | |
| Leslie J. Browne | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 1,723,000 | 4,157,800 | - | - | Common Stock Option | |
| Warren J. Isabelle | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Sep 2013 | 265,000 | 755,000 | - | - | Common Stock Option | |
| Leslie J. Browne | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 May 2013 | 30,000 | 49,000 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2013 | 244,186 | 1,704,765 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2013 | 255,814 | 1,611,761 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2013 | 273,256 | 2,716,572 | - | - | Common Stock Option | |
| Christopher Forbes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2013 | 238,372 | 1,684,193 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2013 | 139,534 | 1,621,215 | - | - | Common Stock Option | |
| Rudolf Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2013 | 296,512 | 2,214,851 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2013 | 162,790 | 1,372,763 | - | - | Common Stock Option | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2013 | 96,590 | 1,460,579 | - | - | Common Stock Options | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2013 | 71,970 | 1,355,947 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2013 | 145,834 | 2,433,316 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2013 | 89,016 | 1,495,821 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2013 | 56,818 | 1,481,681 | - | - | Common Stock Option | |
| Rudolf Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2013 | 119,318 | 1,918,339 | - | - | Common Stock Options | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2013 | 75,758 | 1,209,973 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 Nov 2012 | 2,500 | 12,757,318 | - | - | Common Stock | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Nov 2012 | 38,000 | 352,785 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 59,090 | 1,383,989 | - | - | Common Stock Options | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 294,000 | 1,324,899 | - | - | Common Stock Options | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 210,000 | 1,177,917 | - | - | Common Stock Options | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 106,060 | 1,283,977 | - | - | Common Stock Options | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 420,000 | 2,122,330 | - | - | Common Stock Options | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 165,152 | 2,287,482 | - | - | Common Stock Options | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 124,242 | 1,426,805 | - | - | Common Stock Options | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 252,000 | 1,302,563 | - | - | Common Stock Options | |
| Joel Brooks | CFO, Secretary and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 780,000 | 1,797,200 | - | - | Common Stock Options | |
| John E. Thompson | Director, CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 780,000 | 1,823,276 | - | - | Common Stock Options | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 77,272 | 1,424,863 | - | - | Common Stock Options | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 294,000 | 1,347,591 | - | - | Common Stock Options | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 210,000 | 1,682,657 | - | - | Common Stock Options | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 136,364 | 1,819,021 | - | - | Common Stock Options | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 210,000 | 1,051,185 | - | - | Common Stock Options | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 103,030 | 1,154,215 | - | - | Common Stock Options | |
| Richard Dondero | VP-Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 780,000 | 1,960,124 | - | - | Common Stock Options | |
| Leslie J. Browne | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 1,365,000 | 3,458,550 | - | - | Common Stock Option | |
| Warren J. Isabelle | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2012 | 210,000 | 490,000 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | 08 Aug 2012 | 200 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Harlan W. Waksal | None | 08 Aug 2012 | 858,517 | 2,805,750 | - | - | Common Stock | ||
| Christopher Forbes | Director, Ten Percent Owner | 08 Aug 2012 | 1,000 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Christopher Forbes | Director, Ten Percent Owner | 08 Aug 2012 | 4,292,583 | 12,754,818 | - | - | Common Stock | ||
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2012 | 10,976 | 1,030,899 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2012 | 31,708 | 967,917 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2012 | 46,342 | 1,702,330 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2012 | 35,366 | 1,050,563 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2012 | 10,976 | 1,053,591 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2012 | 40,244 | 1,472,657 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2012 | 34,146 | 841,185 | - | - | Common Stock Option | |
| Leslie J. Browne | President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Mar 2012 | 10,000 | 19,000 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2012 | 15,626 | 1,019,923 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2012 | 20,834 | 936,209 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2012 | 45,834 | 1,655,988 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2012 | 36,458 | 1,015,197 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2012 | 15,626 | 1,042,615 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2012 | 40,626 | 1,432,413 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2012 | 29,166 | 767,039 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Jan 2012 | 961,538 | 1,902,590 | - | - | Common Stock | |
| Christopher Forbes | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Jan 2012 | 192,308 | 8,239,021 | - | - | Common Stock | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Dec 2011 | 44,039 | 314,785 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2011 | 82,500 | 1,004,297 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2011 | 80,000 | 915,375 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2011 | 147,500 | 1,610,154 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2011 | 87,500 | 1,018,739 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2011 | 82,500 | 1,026,989 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2011 | 105,000 | 1,646,787 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Nov 2011 | 62,500 | 817,873 | - | - | Common Stock Option | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 230,000 | 921,797 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 155,000 | 835,375 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 305,000 | 1,462,654 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 190,000 | 931,239 | - | - | Common Stock Option | |
| Joel Brooks | CFO, Secretary and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 468,000 | 1,325,500 | - | - | Common Stock Option | |
| John E. Thompson | Director, EVP and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 468,000 | 1,263,676 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 230,000 | 944,489 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 300,000 | 1,616,787 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 155,000 | 1,316,787 | - | - | Common Stock | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 155,000 | 755,373 | - | - | Common Stock Option | |
| Richard Dondero | VP - Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 468,000 | 1,460,924 | - | - | Common Stock Option | |
| Leslie J. Browne | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 819,000 | 0 | - | - | Common Stock Option | |
| Warren J. Isabelle | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2011 | 155,000 | 280,000 | - | - | Common Stock Option | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Jun 2011 | 20,000 | 270,746 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2011 | 27,778 | 691,797 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2011 | 32,408 | 680,375 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2011 | 51,852 | 1,157,654 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2011 | 37,962 | 741,239 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2011 | 27,778 | 714,489 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2011 | 48,148 | 1,161,787 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2011 | 28,704 | 600,373 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Mar 2011 | 15,000 | 7,452,289 | - | - | Common Stock | |
| Leslie J. Browne | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Mar 2011 | 3,000 | 9,000 | - | - | Common Stock | |
| Leslie J. Browne | President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 Feb 2011 | 3,000 | 3,000 | - | - | Common Stock | |
| Leslie J. Browne | President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 Feb 2011 | 3,000 | 6,000 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2011 | 18,104 | 664,019 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2011 | 32,758 | 647,967 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2011 | 45,690 | 1,105,802 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2011 | 32,758 | 703,277 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2011 | 18,104 | 686,711 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2011 | 31,896 | 1,113,639 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2011 | 29,310 | 571,669 | - | - | Common Stock Option | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 43,269 | 495,915 | - | - | Common Stock Option | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 150,000 | 645,915 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 100,000 | 515,209 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 50,000 | 615,209 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 50,000 | 565,209 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 37,177 | 415,209 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 500,000 | 1,060,112 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 200,000 | 560,112 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 96,154 | 360,112 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 67,308 | 670,519 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 125,000 | 603,211 | - | - | Common Stock Option | |
| Joel Brooks | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 425,000 | 882,500 | - | - | Common Stock Option | |
| John E. Thompson | Director, EVP and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 425,000 | 995,676 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 49,038 | 518,607 | - | - | Common Stock Option | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 150,000 | 668,607 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 71,792 | 981,743 | - | - | Common Stock Option | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 100,000 | 1,081,743 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 71,154 | 442,359 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 100,000 | 542,359 | - | - | Common Stock Option | |
| Richard Dondero | VP - Research and Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 425,000 | 1,232,924 | - | - | Common Stock Option | |
| Leslie J. Browne | President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 725,000 | 1,725,000 | - | - | Common Stock Option | |
| Warren J. Isabelle | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Nov 2010 | 100,000 | 125,000 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Jun 2010 | 625,000 | 1,167,333 | - | - | Common Stock Warrant | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Jun 2010 | 200 | 200 | - | - | Series B Convertible Preferred Stock | |
| Christopher Forbes | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Jun 2010 | 3,125,000 | 7,091,477 | - | - | Common Stock Warrant | |
| Christopher Forbes | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 02 Jun 2010 | 1,000 | 1,000 | - | - | Series B Convertible Preferred Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 3,042 | 71,683 | - | - | Common Stock | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 25 May 2010 | 4,694 | 250,746 | - | - | Common Stock | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 25 May 2010 | 15,306 | 246,052 | - | - | Common Stock | |
| David S. Rector | None | 25 May 2010 | 159,063 | 230,746 | - | - | Common Stock | ||
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 7,090 | 68,641 | - | - | Common Stock | |
| Angel Alvarez-Pérez | None | 25 May 2010 | 30,459 | 40,068 | - | - | Common Stock | ||
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 1,358 | 9,021 | - | - | Common Stock | |
| Angel Alvarez-Pérez | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 588 | 9,609 | - | - | Common Stock | |
| Harlan W. Waksal | None | 25 May 2010 | 631,176 | 822,168 | - | - | Common Stock | ||
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 12,078 | 190,992 | - | - | Common Stock | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 28,135 | 178,914 | - | - | Common Stock | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 78,469 | 3,305,489 | - | - | Common Stock | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 182,840 | 3,227,020 | - | - | Common Stock | |
| Christopher Forbes | Director, Ten Percent Owner | 25 May 2010 | 4,101,800 | 7,407,289 | - | - | Common Stock | ||
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 3,470 | 58,637 | - | - | Common Stock | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 1,487 | 60,124 | - | - | Common Stock | |
| John N. Braca | None | 25 May 2010 | 77,840 | 137,964 | - | - | Common Stock | ||
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 28,135 | 410,684 | - | - | Common Stock | |
| Ruedi Stalder | None | 25 May 2010 | 631,176 | 1,053,938 | - | - | Common Stock | ||
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 12,078 | 422,762 | - | - | Common Stock | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 6,016 | 500,165 | - | - | Common Stock | |
| Thomas C. Quick | None | 25 May 2010 | 314,742 | 814,907 | - | - | Common Stock | ||
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 14,029 | 494,149 | - | - | Common Stock | |
| Warren J. Isabelle | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 3,470 | 22,437 | - | - | Common Stock | |
| Warren J. Isabelle | None | 25 May 2010 | 77,840 | 101,764 | - | - | Common Stock | ||
| Warren J. Isabelle | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2010 | 1,487 | 23,924 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 11,066 | 452,646 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 75,000 | 378,032 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 22,951 | 263,958 | - | - | Common Stock Option | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 19,262 | 478,211 | - | - | Common Stock Option | |
| John N. Braca | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 May 2010 | 2,000 | 70,559 | - | - | Common Stock Warrant | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 11,066 | 439,569 | - | - | Common Stock Option | |
| John N. Braca | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 May 2010 | 2,000 | 55,167 | - | - | Common Stock | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 30,000 | 469,569 | - | - | Common Stock Options | |
| Ruedi Stalder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 20,082 | 909,951 | - | - | Common Stock Option | |
| Thomas C. Quick | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2010 | 13,934 | 371,205 | - | - | Common Stock Option | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 19,803 | 27,845 | - | - | Common Stock Warrant | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 33,006 | 60,851 | - | - | Common Stock Warrant | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 33,006 | 115,861 | - | - | Common Stock Warrant | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 22,004 | 82,855 | - | - | Common Stock Warrant | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 34,218 | 61,551 | - | - | Common Stock | |
| David S. Rector | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 50,834 | 441,580 | - | - | Common Stock Option | |
| David S. Rector | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 22,004 | 137,865 | - | - | Common Stock Warrant | |
| Angel Alvarez-Pérez | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 37,500 | 273,866 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 29,166 | 303,032 | - | - | Common Stock Option | |
| Angel Alvarez-Pérez | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 3,792 | 5,806 | - | - | Common Stock Warrant | |
| Angel Alvarez-Pérez | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 4,213 | 16,339 | - | - | Common Stock Warrant | |
| Angel Alvarez-Pérez | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 4,213 | 26,872 | - | - | Common Stock Warrant | |
| Angel Alvarez-Pérez | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 6,320 | 22,659 | - | - | Common Stock | |
| Angel Alvarez-Pérez | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 6,320 | 12,126 | - | - | Common Stock Warrant | |
| Angel Alvarez-Pérez | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 6,552 | 7,663 | - | - | Common Stock | |
| Harlan W. Waksal | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 77,500 | 241,007 | - | - | Common Stock Option | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 78,581 | 105,769 | - | - | Common Stock Warrant | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 130,969 | 236,738 | - | - | Common Stock Warrant | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 130,969 | 455,020 | - | - | Common Stock Warrant | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 135,779 | 150,779 | - | - | Common Stock | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 87,313 | 324,051 | - | - | Common Stock Warrant | |
| Harlan W. Waksal | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 87,313 | 542,333 | - | - | Common Stock Warrant | |
| Christopher Forbes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 54,166 | 458,949 | - | - | Common Stock Option | |
| Joel Brooks | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 300,000 | 457,500 | - | - | Common Stock Option | |
| John N. Braca | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 16,152 | 34,871 | - | - | Common Stock Warrant | |
| John N. Braca | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 9,691 | 18,719 | - | - | Common Stock Warrant | |
| John N. Braca | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 10,768 | 72,559 | - | - | Common Stock Warrant | |
| John N. Braca | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 10,768 | 45,639 | - | - | Common Stock Warrant | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 15,000 | 377,669 | - | - | Common Stock Option | |
| John N. Braca | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 16,152 | 61,791 | - | - | Common Stock Warrant | |
| John N. Braca | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2010 | 50,834 | 428,503 | - | - | Common Stock Option | |
| John N. Braca | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 16,745 | 53,167 | - | - | Common Stock | |
| Ruedi Stalder | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 130,969 | 283,467 | - | - | Common Stock Warrant | |
| Ruedi Stalder | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Feb 2010 | 135,779 | 382,549 | - | - | Common Stock |