1.25 -0.05 (-3.85%)
1,433 XNAS Volume
XNAS 19 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Scott L. Tarriff | Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.27 per share. | 28 Feb 2024 | 2,119 | 460,621 (3%) | 0% | 6.3 | 13,286 | Common Stock |
| Tarriff L. Scott | Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 12,950 | 465,894 (3%) | 0% | - | Common Stock | |
| Brian Cahill | CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 3,800 | 49,547 (0%) | 0% | 0 | Common Stock | |
| L. Tarriff Scott | Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.44 per share. | 27 Feb 2024 | 3,154 | 462,740 (3%) | 0% | 6.4 | 20,312 | Common Stock |
| Cahill Brian | CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.44 per share. | 27 Feb 2024 | 1,589 | 47,958 (0%) | 0% | 6.4 | 10,233 | Common Stock |
| Cahill Brian | CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.85 per share. | 02 Feb 2024 | 934 | 45,747 (0%) | 0% | 5.9 | 5,464 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.13 per share. | 05 Jan 2024 | 735 | 46,681 (0%) | 0% | 5.1 | 3,771 | Common Stock |
| Scott Tarriff L. | Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.13 per share. | 05 Jan 2024 | 4,322 | 541,125 (3%) | 0% | 5.1 | 22,172 | Common Stock |
| Michael Graves | Director, Interim Executive Chair & PEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Dec 2023 | 293,000 | 293,000 | - | - | Employee Stock Option (right to buy) | |
| Cahill Brian | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.76 per share. | 18 Dec 2023 | 452 | 47,416 (0%) | 0% | 4.8 | 2,152 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 19.98 per share. | 16 May 2023 | 15,000 | 587,311 (4%) | 0% | 20.0 | 299,700 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 21.06 per share. | 11 May 2023 | 14,800 | 1,595,134 (11%) | 0% | 21.1 | 311,688 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 20.42 per share. | 11 May 2023 | 11,869 | 1,609,934 (11%) | 0% | 20.4 | 242,365 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 19.69 per share. | 11 May 2023 | 3,131 | 1,621,803 (11%) | 0% | 19.7 | 61,649 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 21.52 per share. | 11 May 2023 | 200 | 1,594,934 (11%) | 0% | 21.5 | 4,304 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 20.71 per share. | 11 May 2023 | 15,000 | 1,624,934 (11%) | 0% | 20.7 | 310,650 | Common Stock |
| Michael Graves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2023 | 16,253 | 16,253 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2023 | 16,253 | 16,253 | - | - | Stock Option (right to buy) | |
| Jennifer K Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2023 | 16,253 | 16,253 | - | - | Stock Option (right to buy) | |
| Robert L. Glenning | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2023 | 16,253 | 16,253 | - | - | Stock Option (right to buy) | |
| Richard A. Edlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2023 | 16,253 | 16,253 | - | - | Stock Option (right to buy) | |
| Luciana Borio | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Mar 2023 | 16,253 | 16,253 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2023 | 70,900 | 1,639,934 (11%) | 0% | 0 | Common Stock | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 28.00 per share. | 28 Feb 2023 | 3,113 | 1,569,034 (11%) | 0% | 28 | 87,164 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 28.00 per share. | 28 Feb 2023 | 718 | 29,368 (0%) | 0% | 28 | 20,104 | Common Stock |
| Brian Cahill | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2023 | 18,500 | 47,868 (0%) | 0% | 0 | Common Stock | |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 34.09 per share. | 02 Feb 2023 | 785 | 30,086 (0%) | 0% | 34.1 | 26,761 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.21 per share. | 30 Jan 2023 | 601 | 30,871 (0%) | 0% | 33.2 | 19,959 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.64 per share. | 23 Jan 2023 | 3,732 | 1,572,147 (11%) | 0% | 33.6 | 125,544 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 29.26 per share. | 05 Jan 2023 | 3,827 | 1,575,879 (11%) | 0% | 29.3 | 111,978 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 29.26 per share. | 05 Jan 2023 | 734 | 31,472 (0%) | 0% | 29.3 | 21,477 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.03 per share. | 19 Dec 2022 | 461 | 32,206 (0%) | 0% | 30.0 | 13,844 | Common Stock |
| Richard A. Edlin | Director | Sale of securities on an exchange or to another person at price $ 30.99 per share. | 06 Sep 2022 | 6,800 | 22,600 (0%) | 0% | 31.0 | 210,732 | Common Stock |
| Michael Graves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 11,200 | 11,200 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 34,800 | 1,579,706 (11%) | 0% | 0 | Common Stock | |
| Steven B. Ratoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 11,200 | 11,200 | - | - | Stock Option (right to buy) | |
| Jennifer K Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 11,200 | 11,200 | - | - | Stock Option (right to buy) | |
| Robert L. Glenning | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 11,200 | 11,200 | - | - | Stock Option (right to buy) | |
| Richard A. Edlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 11,200 | 11,200 | - | - | Stock Option (right to buy) | |
| Brian Cahill | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 8,000 | 32,667 (0%) | 0% | 0 | Common Stock | |
| Luciana Borio | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 11,200 | 11,200 | - | - | Stock Option (right to buy) | |
| Michael Moran | EVP, Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2022 | 10,400 | 32,115 (0%) | 0% | 0 | Common Stock | |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 45.03 per share. | 02 Feb 2022 | 805 | 24,667 (0%) | 0% | 45.0 | 36,249 | Common Stock |
| Michael Moran | EVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 45.03 per share. | 02 Feb 2022 | 742 | 21,715 (0%) | 0% | 45.0 | 33,412 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 45.94 per share. | 31 Jan 2022 | 626 | 25,472 (0%) | 0% | 45.9 | 28,758 | Common Stock |
| Michael Moran | EVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 45.94 per share. | 31 Jan 2022 | 210 | 22,457 (0%) | 0% | 45.9 | 9,647 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.63 per share. | 07 Jan 2022 | 263 | 26,098 (0%) | 0% | 50.6 | 13,316 | Common Stock |
| Michael Moran | EVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.63 per share. | 07 Jan 2022 | 90 | 22,667 (0%) | 0% | 50.6 | 4,557 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.69 per share. | 05 Jan 2022 | 738 | 26,361 (0%) | 0% | 50.7 | 37,409 | Common Stock |
| Michael Moran | EVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.69 per share. | 05 Jan 2022 | 1,511 | 22,757 (0%) | 0% | 50.7 | 76,593 | Common Stock |
| Luciana Borio | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2021 | 13,500 | 13,500 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.78 per share. | 08 Apr 2021 | 2,340 | 25,024 (0%) | 0% | 8.8 | 20,545 | Common Stock |
| Steven B. Ratoff | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Apr 2021 | 2,340 | 0 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Apr 2021 | 2,340 | 0 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Apr 2021 | 2,340 | 0 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.42 per share. | 08 Apr 2021 | 2,340 | 27,364 (0%) | 0% | 4.4 | 10,343 | Common Stock |
| Steven B. Ratoff | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.78 per share. | 08 Apr 2021 | 2,340 | 22,684 (0%) | 0% | 8.8 | 20,545 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.78 per share. | 01 Apr 2021 | 31,201 | 1,561,184 (11%) | 0% | 8.8 | 273,945 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Apr 2021 | 16,340 | 1,529,983 (11%) | 0% | 0 | Common Stock | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 41.87 per share. | 01 Apr 2021 | 16,278 | 1,544,906 (11%) | 0% | 41.9 | 681,560 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2021 | 31,201 | 0 | - | - | Employee Stock Option (right to buy) | |
| Michael Graves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 13,500 | 13,500 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 13,500 | 13,500 | - | - | Stock Option (right to buy) | |
| David Pernock | Pres & Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 9,700 | 54,625 (0%) | 0% | 0 | Common Stock | |
| Jennifer K Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 13,500 | 13,500 | - | - | Stock Option (right to buy) | |
| Robert L. Glenning | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 13,500 | 13,500 | - | - | Stock Option (right to buy) | |
| Richard A. Edlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 13,500 | 13,500 | - | - | Stock Option (right to buy) | |
| Judith Ng-Cashin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 2,000 | 2,000 (0%) | 0% | 0 | Common Stock | |
| Brian Cahill | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2021 | 8,900 | 27,566 (0%) | 0% | 0 | Common Stock | |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 46.67 per share. | 29 Jan 2021 | 637 | 18,666 (0%) | 0% | 46.7 | 29,729 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 47.70 per share. | 23 Jan 2021 | 4,631 | 1,546,323 (11%) | 0% | 47.7 | 220,899 | Common Stock |
| David Pernock | Pres & Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 47.70 per share. | 23 Jan 2021 | 1,892 | 44,925 (0%) | 0% | 47.7 | 90,248 | Common Stock |
| David Pernock | Pres & Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.97 per share. | 07 Jan 2021 | 906 | 46,817 (0%) | 0% | 51.0 | 46,179 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.97 per share. | 07 Jan 2021 | 237 | 14,303 (0%) | 0% | 51.0 | 12,080 | Common Stock |
| David Pernock | Pres & Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.02 per share. | 05 Jan 2021 | 2,088 | 47,723 (0%) | 0% | 50.0 | 104,442 | Common Stock |
| Brian Cahill | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.02 per share. | 05 Jan 2021 | 746 | 14,540 (0%) | 0% | 50.0 | 37,315 | Common Stock |
| Judith Ng-Cashin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2020 | 35,000 | 35,000 | - | - | Employee Stock Option (right to buy) | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.98 per share. | 23 Jan 2020 | 7,548 | 1,550,954 (11%) | 0% | 58.0 | 437,633 | Common Stock |
| David Pernock | Pres. & Chief Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.98 per share. | 23 Jan 2020 | 1,793 | 49,811 (0%) | 0% | 58.0 | 103,958 | Common Stock |
| Adrian Hepner | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.98 per share. | 23 Jan 2020 | 1,630 | 48,784 (0%) | 0% | 58.0 | 94,507 | Common Stock |
| Pete A. Meyers | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.98 per share. | 23 Jan 2020 | 1,653 | 43,615 (0%) | 0% | 58.0 | 95,841 | Common Stock |
| Michael Graves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 58,300 | 1,558,502 (11%) | 0% | - | Common Stock | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 145,700 | 145,700 | - | - | Employee Stock Option (right to buy) | |
| Steven B. Ratoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| David Pernock | Pres. & Chief Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.38 per share. | 05 Jan 2020 | 904 | 51,604 (0%) | 0% | 57.4 | 51,872 | Common Stock |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 51,000 | 51,000 | - | - | Employee Stock Option (right to buy) | |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 21,500 | 52,508 (0%) | 0% | - | Common Stock | |
| Adrian Hepner | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.38 per share. | 05 Jan 2020 | 815 | 50,414 (0%) | 0% | 57.4 | 46,765 | Common Stock |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 24,000 | 51,229 (0%) | 0% | - | Common Stock | |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 55,000 | 55,000 | - | - | Employee Stock Option (right to buy) | |
| Jennifer K Simpson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 48,000 | 48,000 | - | - | Employee Stock Option (right to buy) | |
| Pete A. Meyers | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.38 per share. | 05 Jan 2020 | 632 | 45,268 (0%) | 0% | 57.4 | 36,264 | Common Stock |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 19,500 | 45,900 (0%) | 0% | - | Common Stock | |
| Robert Glenning | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Richard A. Edlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2020 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Jennifer K Simpson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Oct 2019 | 10,000 | 10,000 | - | - | Stock option (right to buy) | |
| Douglas Braunstein | None | Sale of securities on an exchange or to another person at price $ 57.95 per share. | 09 May 2019 | 59,223 | 911,777 (6%) | 0% | 58.0 | 3,431,973 | Common Stock |
| Douglas Braunstein | None | Sale of securities on an exchange or to another person at price $ 56.14 per share. | 09 May 2019 | 100,000 | 811,777 (5%) | 0% | 56.1 | 5,614,000 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 50.15 per share. | 01 Apr 2019 | 24,975 | 1,500,202 (10%) | 0% | 50.1 | 1,252,496 | Commn Stock |
| Sander A. Flaum | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.04 per share. | 05 Mar 2019 | 2,340 | 13,714 (0%) | 0% | 4.0 | 9,454 | Common Stock |
| Sander A. Flaum | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2019 | 2,340 | 0 | - | - | Stock Option (right to buy) | |
| Sander A. Flaum | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 48.89 per share. | 05 Mar 2019 | 204 | 13,510 (0%) | 0% | 48.9 | 9,974 | Common Stock |
| Steven B. Ratoff | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2019 | 2,340 | 0 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.04 per share. | 04 Mar 2019 | 2,340 | 18,004 (0%) | 0% | 4.0 | 9,454 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 51.81 per share. | 01 Mar 2019 | 12,428 | 1,525,177 (11%) | 0% | 51.8 | 643,895 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 50.51 per share. | 01 Mar 2019 | 12,000 | 1,537,605 (11%) | 0% | 50.5 | 606,120 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 42.30 per share. | 01 Feb 2019 | 900 | 1,549,605 (11%) | 0% | 42.3 | 38,070 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.52 per share. | 01 Feb 2019 | 29,185 | 1,550,505 (11%) | 0% | 41.5 | 1,211,761 | Common Stock |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Sander A. Flaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 61,300 | 1,579,690 (11%) | 0% | - | Common Stock | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 137,200 | 137,200 | - | - | Employee Stock Option (right to buy) | |
| Steven B. Ratoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Douglas Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Robert Glenning | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Richard A. Edlin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jan 2019 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 46,600 | 46,600 | - | - | Employee Stock Option (right to buy) | |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 20,900 | 31,008 (0%) | 0% | - | Common Stock | |
| David Pernock | Pres. & Chief Comm. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 41.33 per share. | 07 Jan 2019 | 858 | 10,108 (0%) | 0% | 41.3 | 35,461 | Common Stock |
| Adrian Hepner | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 41.33 per share. | 07 Jan 2019 | 771 | 8,229 (0%) | 0% | 41.3 | 31,865 | Common Stock |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 42,500 | 42,500 | - | - | Employee Stock Option (right to buy) | |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 19,000 | 27,229 (0%) | 0% | - | Common Stock | |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 19,300 | 26,400 (0%) | 0% | - | Common Stock | |
| Pete A. Meyers | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 41.33 per share. | 07 Jan 2019 | 600 | 7,100 (0%) | 0% | 41.3 | 24,798 | Common Stock |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2019 | 43,200 | 43,200 | - | - | Employee Stock Option (right to buy) | |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 39.30 per share. | 02 Jan 2019 | 6,500 | 1,543,459 (11%) | 0% | 39.3 | 255,450 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 40.57 per share. | 02 Jan 2019 | 302 | 1,518,390 (11%) | 0% | 40.6 | 12,252 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 39.70 per share. | 02 Jan 2019 | 5,670 | 1,518,692 (11%) | 0% | 39.7 | 225,099 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 39.04 per share. | 02 Jan 2019 | 10,597 | 1,524,362 (11%) | 0% | 39.0 | 413,707 | Common Stock |
| Scott L. Tarriff | Director, CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 40.03 per share. | 02 Jan 2019 | 8,500 | 1,534,959 (11%) | 0% | 40.0 | 340,255 | Common Stock |
| Scott L. Tarriff | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jun 2018 | 124,804 | 0 | - | - | Stock Option (Right to Buy) | |
| Scott L. Tarriff | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.04 per share. | 28 Jun 2018 | 124,804 | 1,549,959 (10%) | 0% | 4.0 | 504,208 | Common Stock |
| Scott L. Tarriff | Director, CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 52.69 per share. | 30 Mar 2018 | 57,895 | 1,425,155 (9%) | 0% | 52.7 | 3,050,488 | Common Stock |
| Scott L. Tarriff | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Mar 2018 | 113,104 | 0 | - | - | Employee Stock Option (Right to Buy) | |
| Scott L. Tarriff | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.04 per share. | 30 Mar 2018 | 113,104 | 1,483,050 (9%) | 0% | 4.0 | 456,940 | Common Stock |
| Sander A. Flaum | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2018 | 2,340 | 0 | - | - | Stock Option (Right to Buy) | |
| Sander A. Flaum | None | Sale of securities on an exchange or to another person at price $ 53.94 per share. | 05 Mar 2018 | 2,340 | 11,374 (0%) | 0% | 53.9 | 126,220 | Common Stock |
| Sander A. Flaum | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.90 per share. | 05 Mar 2018 | 2,340 | 13,714 (0%) | 0% | 0.9 | 2,106 | Common Stock |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Sander A. Flaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Scott L. Tarriff | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 157,000 | 157,000 | - | - | Employee Stock Option (Right to Buy) | |
| Scott L. Tarriff | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 189,000 | 189,000 | - | - | Peformance Stock Unit | |
| Steven B. Ratoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 10,000 | 10,966 (0%) | 0% | 0 | Common Stock | |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 30,000 | 30,000 | - | - | Performance Stock Unit | |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 50,000 | 50,000 | - | - | Employee Stock Option (Right to Buy) | |
| Douglas Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 43,000 | 43,000 | - | - | Employee Stock Option (Right to Buy) | |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 27,000 | 27,000 | - | - | Performance Stock Unit | |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 9,000 | 9,000 (0%) | 0% | 0 | Common Stock | |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 7,000 | 7,700 (0%) | 0% | 0 | Common Stock | |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 21,000 | 21,000 | - | - | Performance Stock Unit | |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 37,000 | 37,000 | - | - | Employee Stock Option (Right to Buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 9,000 | 9,000 | - | - | Performance Stock Unit | |
| Steven L. Krill | EVP & Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 15,000 | 15,000 | - | - | Employee Stock Option (Right to Buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 3,000 | 3,000 (0%) | 0% | 0 | Common Stock | |
| Robert Glenning | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Edlin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jan 2018 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Steven B. Ratoff | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2017 | 2,340 | 0 | - | - | Stock Option (Right to Buy) | |
| Steven B. Ratoff | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.90 per share. | 18 Dec 2017 | 2,340 | 15,664 (0%) | 0% | 0.9 | 2,106 | Common Stock |
| Pete A. Meyers | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 55.45 per share. | 16 Aug 2017 | 350 | 700 (0%) | 0% | 55.4 | 19,406 | Common Stock |
| Douglas Braunstein | None | Purchase of securities on an exchange or from another person at price $ 50.09 per share. | 09 Aug 2017 | 1,584 | 971,000 (6%) | 0% | 50.1 | 79,338 | Common Stock |
| Douglas Braunstein | None | Purchase of securities on an exchange or from another person at price $ 49.21 per share. | 09 Aug 2017 | 15,206 | 969,416 (6%) | 0% | 49.2 | 748,258 | Common Stock |
| Douglas Braunstein | None | Purchase of securities on an exchange or from another person at price $ 48.06 per share. | 09 Aug 2017 | 3,610 | 954,210 (6%) | 0% | 48.1 | 173,490 | Common Stock |
| Pete A. Meyers | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 71.49 per share. | 12 Jun 2017 | 350 | 350 (0%) | 0% | 71.5 | 25,021 | Common Stock |
| David Pernock | Pres. & Chief Comm. Officer | Purchase of securities on an exchange or from another person at price $ 79.69 per share. | 19 May 2017 | 255 | 966 (0%) | 0% | 79.7 | 20,321 | Common Stock |
| David Pernock | Pres. & Chief Comm. Officer | Purchase of securities on an exchange or from another person at price $ 82.24 per share. | 16 May 2017 | 200 | 711 (0%) | 0% | 82.2 | 16,448 | Common Stock |
| Pete A. Meyers | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2017 | 50,000 | 50,000 | - | - | Employee Stock Option (Right to Buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 80.09 per share. | 22 Mar 2017 | 7,100 | 0 (0%) | 0% | 80.1 | 568,641 | Common Stock |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 82.06 per share. | 22 Mar 2017 | 7,025 | 0 (0%) | 0% | 82.1 | 576,489 | Common Stock |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2017 | 5,023 | 457 | - | - | Employee Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2017 | 2,077 | 6,875 | - | - | Employee Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2017 | 2,025 | 4,850 | - | - | Employee Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2017 | 5,000 | 15,000 | - | - | Employee Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.63 per share. | 22 Mar 2017 | 5,000 | 7,025 (0%) | 0% | 12.6 | 63,150 | Common Stock |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.42 per share. | 22 Mar 2017 | 5,023 | 5,023 (0%) | 0% | 4.4 | 22,202 | Common Stock |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.67 per share. | 22 Mar 2017 | 2,077 | 7,100 (0%) | 0% | 12.7 | 26,316 | Common Stock |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.67 per share. | 22 Mar 2017 | 2,025 | 2,025 (0%) | 0% | 12.7 | 25,657 | Common Stock |
| Richard A. Edlin | None | Purchase of securities on an exchange or from another person at price $ 79.44 per share. | 22 Mar 2017 | 6,000 | 29,400 (0%) | 0% | 79.4 | 476,640 | Common Stock |
| David Pernock | Pres. & Chief Comm. Officer | Purchase of securities on an exchange or from another person at price $ 83.98 per share. | 21 Mar 2017 | 61 | 511 (0%) | 0% | 84.0 | 5,123 | Common Stock |
| Richard A. Edlin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2017 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| David Pernock | Pres. & Chief Comm. Officer | Purchase of securities on an exchange or from another person at price $ 77.84 per share. | 09 Mar 2017 | 450 | 450 (0%) | 0% | 77.8 | 35,028 | Common Stock |
| David E. Riggs | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Sander A. Flaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 200,900 | 200,900 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| David Pernock | Pres. & Chief Comm. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| Douglas Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Adrian Hepner | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 67,200 | 67,200 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 42,000 | 42,000 | - | - | Stock Option (right to buy) | |
| Robert Glenning | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2017 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 7,317 | 32,683 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 5,126 | 58,591 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 6,270 | 6,270 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 7,317 | 7,317 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 2,683 | 2,683 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 5,126 | 5,126 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 3,730 | 5,480 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 10,000 | 22,683 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 5,127 | 53,464 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 6,270 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 7,317 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 2,683 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 5,126 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 2,683 | 8,952 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 7,569 | 63,717 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 3,730 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 2,683 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 10,000 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 7,569 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Dec 2016 | 5,127 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 6,270 | 11,635 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 2,683 | 20,000 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 3,730 | 3,730 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 2,683 | 2,683 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 10,000 | 10,000 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 7,569 | 7,569 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2016 | 5,127 | 5,127 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Dec 2016 | 10,000 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2016 | 10,000 | 10,000 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2016 | 10,000 | 9,210 | - | - | Stock Option (right to buy) | |
| Sander A. Flaum | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 28 Nov 2016 | 5,000 | 11,374 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 200 | 2,530 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 200 | 200 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 2,530 | 2,530 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 1,307 | 19,210 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Nov 2016 | 1,950 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Nov 2016 | 1,307 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 1,950 | 0 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Nov 2016 | 200 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Nov 2016 | 2,530 | 0 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 2,530 | 0 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 1,950 | 1,950 | - | - | Common Stock | |
| Steven L. Krill | EVP & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Nov 2016 | 1,307 | 1,307 | - | - | Common Stock | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Nov 2016 | 167 | 3,961,752 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Nov 2016 | 1,300 | 26,174 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Nov 2016 | 15,368 | 3,961,919 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Nov 2016 | 300 | 7,677 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Nov 2016 | 100 | 3,961,652 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Nov 2016 | 15,551 | 3,944,401 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 10 Nov 2016 | 1,700 | 3,959,952 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Nov 2016 | 5,030 | 4,126,087 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Nov 2016 | 4,200 | 4,099,787 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Nov 2016 | 9,030 | 4,103,987 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Nov 2016 | 1,380 | 4,124,707 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Nov 2016 | 19,581 | 4,080,206 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Nov 2016 | 11,690 | 4,113,017 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 07 Nov 2016 | 102,919 | 3,977,287 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 02 Nov 2016 | 50,329 | 4,177,287 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 02 Nov 2016 | 146,371 | 4,227,616 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 02 Nov 2016 | 46,170 | 4,181,446 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 02 Nov 2016 | 800 | 7,977 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 02 Nov 2016 | 2,100 | 27,474 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 30 Sep 2016 | 22,100 | 4,373,987 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 29 Sep 2016 | 77,900 | 4,396,087 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 21 Sep 2016 | 654 | 29,574 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 21 Sep 2016 | 97,149 | 4,475,785 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 21 Sep 2016 | 194 | 8,777 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 21 Sep 2016 | 1,798 | 4,473,987 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 12,224 | 4,618,075 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 22 | 9,037 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 224 | 30,228 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 49 | 9,059 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 75 | 30,452 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 12,958 | 4,630,299 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 11,345 | 4,606,730 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 66 | 8,971 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 166 | 30,527 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Sep 2016 | 33,796 | 4,572,934 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Aug 2016 | 34 | 9,131 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Aug 2016 | 76 | 30,693 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Aug 2016 | 113 | 30,769 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Aug 2016 | 17,118 | 4,654,763 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Aug 2016 | 23 | 9,108 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Aug 2016 | 11,506 | 4,643,257 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 8,070 | 4,745,989 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 11,770 | 4,717,949 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 4,723 | 4,681,627 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 49 | 5,533 | - | - | Common Stock $0,001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 31,599 | 4,686,350 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 9,848 | 4,671,779 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 16,667 | 4,754,059 | - | - | Common Stock, $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 16,270 | 4,729,719 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 394 | 30,978 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 96 | 30,882 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 163 | 31,372 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 117 | 5,416 | - | - | Common Stock $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Aug 2016 | 29 | 5,387 | - | - | Common Stock $0.001 par value | |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Aug 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Douglas Braunstein | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jul 2016 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Robert Glenning | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jul 2016 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Jay Moorin | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 23 Jun 2016 | 9,903 | 5,582 | - | - | Common Stock $0,001 par value | |
| Jay Moorin | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 20 May 2016 | 4,770,828 | 4,770,828 | - | - | Common Stock, $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 20 May 2016 | 9,360 | 9,360 | - | - | Common Stock $0,001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 12 May 2016 | 4,000 | 55,061 | - | - | Common Stock, $0.001 par value | |
| Jay Moorin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 12 May 2016 | 13,980 | 41,081 | - | - | Common Stock $0,001 par value | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Apr 2016 | 30,765 | 1,369,946 | - | - | Common Stock | |
| Michael Graves | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 15 Mar 2016 | 1,000 | 1,000 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Mar 2016 | 7,802 | 1,412,689 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Mar 2016 | 11,978 | 1,400,711 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Feb 2016 | 2,431 | 1,422,193 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Feb 2016 | 5,367 | 1,433,484 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Feb 2016 | 1,702 | 1,420,491 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Feb 2016 | 5,260 | 1,424,624 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Feb 2016 | 3,600 | 1,429,884 | - | - | Common Stock | |
| Sander A. Flaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| David E. Riggs | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 62,100 | 62,100 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 180,000 | 180,000 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Jan 2016 | 2,773 | 1,438,851 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Jan 2016 | 11,776 | 1,441,624 | - | - | Common Stock | |
| Jay Moorin | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Alain B. Schreiber | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| David Pernock | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Adrian Hepner | Executive VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 62,100 | 62,100 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2016 | 62,100 | 62,100 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Dec 2015 | 2,806 | 1,464,644 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Dec 2015 | 4,744 | 1,459,900 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Dec 2015 | 1,500 | 1,458,400 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Dec 2015 | 3,700 | 1,454,700 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Dec 2015 | 1,300 | 1,453,400 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 02 Nov 2015 | 11,713 | 1,475,076 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 02 Nov 2015 | 7,626 | 1,467,450 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Oct 2015 | 3 | 1,504,664 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Oct 2015 | 1,548 | 1,503,116 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Oct 2015 | 7,027 | 1,496,089 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Oct 2015 | 8,235 | 1,487,854 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Oct 2015 | 1,065 | 1,486,789 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Sep 2015 | 2,526 | 1,518,386 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Sep 2015 | 11,792 | 1,506,594 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Sep 2015 | 1,878 | 1,504,716 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Sep 2015 | 49 | 1,504,667 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 03 Aug 2015 | 10,658 | 1,523,254 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 03 Aug 2015 | 2,342 | 1,520,912 | - | - | Common Stock | |
| Jay Moorin | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 01 Jul 2015 | 2,970 | 59,061 | - | - | Common Stock, $0.001 par value | |
| Steven L. Krill | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2015 | 5,850 | 1,950 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2015 | 2,730 | 2,730 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2015 | 1,400 | 20,517 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2015 | 5,850 | 5,850 | - | - | Common Stock | |
| Steven L. Krill | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Jun 2015 | 5,850 | 0 | - | - | Common Stock | |
| Steven L. Krill | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2015 | 2,730 | 2,730 | - | - | Common Stock | |
| Steven L. Krill | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Jun 2015 | 2,730 | 0 | - | - | Common Stock | |
| Steven L. Krill | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2015 | 1,400 | 1,400 | - | - | Common Stock | |
| Steven L. Krill | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Jun 2015 | 1,400 | 0 | - | - | Common Stock | |
| Jay Moorin | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 06 May 2015 | 9,903 | 62,031 | - | - | Common Stock, $0.001 par value | |
| Sander A. Flaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Apr 2015 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Apr 2015 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Jay Moorin | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Apr 2015 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Alain B. Schreiber | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Apr 2015 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Apr 2015 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| David Pernock | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Apr 2015 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| David Pernock | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2015 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Sander A. Flaum | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 20 Mar 2015 | 9,800 | 19,599 | - | - | Common Stock | |
| Sander A. Flaum | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 20 Mar 2015 | 3,225 | 16,374 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 20 Mar 2015 | 120,000 | 1,549,622 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 20 Mar 2015 | 4,502 | 1,545,120 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 20 Mar 2015 | 1,483 | 1,543,637 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 20 Mar 2015 | 6,015 | 1,537,622 | - | - | Common Stock | |
| Scott L. Tarriff | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 20 Mar 2015 | 3,710 | 1,533,912 | - | - | Common Stock | |
| Sander A. Flaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 5,000 | 5,000 | - | - | Option (right to buy) | |
| David E. Riggs | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 56,286 | 56,286 | - | - | Option (right to buy) | |
| Steven B. Ratoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 5,000 | 5,000 | - | - | Option (right to buy) | |
| Scott L. Tarriff | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 125,000 | 125,000 | - | - | Option (right to buy) | |
| Jay Moorin | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 5,000 | 5,000 | - | - | Option (right to buy) | |
| Alain B. Schreiber | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 5,000 | 5,000 | - | - | Option (right to buy) | |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 5,000 | 5,000 | - | - | Option (right to buy) | |
| Steven L. Krill | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Mar 2015 | 71,286 | 71,286 | - | - | Option (right to buy) | |
| David E. Riggs | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Aug 2014 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Scott L. Tarriff | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Aug 2014 | 75,000 | 75,000 | - | - | Stock Option (right to buy) | |
| Paul Bruinenberg | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Aug 2014 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Aug 2014 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Sander A. Flaum | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 4,680 | 4,680 | - | - | Stock Option (right to buy) | |
| David E. Riggs | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 17,608 | 17,608 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 4,680 | 4,680 | - | - | Stock Option (right to buy) | |
| Jay Moorin | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 4,680 | 4,680 | - | - | Stock Option (right to buy) | |
| Alain B. Schreiber | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 4,680 | 4,680 | - | - | Stock Option (right to buy) | |
| Michael Graves | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 4,680 | 4,680 | - | - | Stock Option (right to buy) | |
| Paul Bruinenberg | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 19,323 | 19,323 | - | - | Stock Option (right to buy) | |
| Steven L. Krill | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2014 | 17,905 | 17,905 | - | - | Stock Option (right to buy) | |
| Steven B. Ratoff | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Apr 2014 | 3,950 | 23,324 | - | - | Common Stock | |
| Steven B. Ratoff | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 03 Apr 2014 | 1,300 | 22,024 | - | - | Common Stock | |
| Steven B. Ratoff | None | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 03 Apr 2014 | 8,700 | 13,324 | - | - | Common Stock | |
| Sander A. Flaum | None | 18 Feb 2014 | 8,580 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Sander A. Flaum | None | 18 Feb 2014 | 8,572 | 0 | - | - | Series B-1 Convertible Preferred Stock | ||
| Sander A. Flaum | None | 18 Feb 2014 | 2,887 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Sander A. Flaum | None | 18 Feb 2014 | 8,580 | 17,940 | - | - | Common Stock, $0.001 par value | ||
| Sander A. Flaum | None | 18 Feb 2014 | 8,572 | 26,512 | - | - | Common Stock, $0.001 par value | ||
| Sander A. Flaum | None | 18 Feb 2014 | 2,887 | 29,399 | - | - | Common Stock, $0.001 par value | ||
| Steven B. Ratoff | None | 18 Feb 2014 | 8,571 | 0 | - | - | Series B-1 Convertible Preferred Stock | ||
| Steven B. Ratoff | None | 18 Feb 2014 | 1,443 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Steven B. Ratoff | None | 18 Feb 2014 | 8,571 | 17,931 | - | - | Common Stock, $0.001 par value | ||
| Steven B. Ratoff | None | 18 Feb 2014 | 1,443 | 19,374 | - | - | Common Stock, $0.001 par value | ||
| Scott L. Tarriff | Director, President and CEO | 18 Feb 2014 | 171,109 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Scott L. Tarriff | Director, President and CEO | 18 Feb 2014 | 25,376 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Scott L. Tarriff | Director, President and CEO | 18 Feb 2014 | 3,438 | 0 | - | - | Series C Warrant | ||
| Scott L. Tarriff | Director, President and CEO | 18 Feb 2014 | 171,109 | 1,643,483 | - | - | Common Stock, $0.001 par value | ||
| Scott L. Tarriff | Director, President and CEO | 18 Feb 2014 | 25,376 | 1,668,859 | - | - | Common Stock, $0.001 par value | ||
| Scott L. Tarriff | Director, President and CEO | 18 Feb 2014 | 763 | 1,669,622 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 1,927,986 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 1,028,613 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 850,520 | 0 | - | - | Series B-1 Convertible Preferred Stock | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 569,538 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 98,368 | 0 | - | - | Series C Warrants | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 62,575 | 0 | - | - | Series B-1 Convertible Preferred Stock | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 9,359 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 1,614 | 0 | - | - | Series C Warrants | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 1,927,986 | 1,966,987 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 1,028,613 | 2,995,600 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 850,520 | 3,846,120 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 569,538 | 4,415,658 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 21,837 | 4,437,495 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 18 Feb 2014 | 333,333 | 4,770,828 | - | - | Common Stock, $0.001 par value | |
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 62,575 | 62,575 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 9,359 | 71,934 | - | - | Common Stock, $0.001 par value | ||
| Jay Moorin | Director, Ten Percent Owner | 18 Feb 2014 | 357 | 72,291 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 1,927,986 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 1,028,613 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 850,520 | 0 | - | - | Series B-1 Convertible Preferred Stock | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 569,538 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 98,368 | 0 | - | - | Series C Warrants | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 62,575 | 0 | - | - | Series B-1 Convertible Preferred Stock | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 9,359 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 1,614 | 0 | - | - | Series C Warrants | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 1,927,986 | 1,966,987 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 1,028,613 | 2,995,600 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 850,520 | 3,846,120 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 569,538 | 4,415,658 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 21,837 | 4,437,495 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 18 Feb 2014 | 333,333 | 4,770,828 | - | - | Common Stock, $0.001 par value | |
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 62,575 | 62,575 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 9,359 | 71,934 | - | - | Common Stock, $0.001 par value | ||
| Alain B. Schreiber | Director, Ten Percent Owner | 18 Feb 2014 | 357 | 72,291 | - | - | Common Stock, $0.001 par value |