113.8K XNAS Volume
XNAS 21 Mar, 2025 2:22 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| David Natan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 700,000 | 700,000 | - | - | Non-Qualified Stock Option (Right to Buy) | |
| Avraham Ben-Tzvi | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 700,000 | 700,000 | - | - | Non-Qualified Stock Option (Right to Buy) | |
| David E. Lazar | Interim CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 1,745,262 | 354,738 | - | - | Series D Convertible Preferred Stock | |
| David E. Lazar | Interim CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 2,650,000 | 2,650,000 (15%) | 15% | - | Common Stock | |
| David E. Lazar | Interim CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 191,978,820 | 194,628,820 (999.99%) | 1116% | - | Common Stock | |
| David E. Lazar | Interim CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.03 per share. | 26 Feb 2025 | 194,628,820 | 0 (0%) | 1131% | 0.0 | 5,507,996 | Common Stock |
| David E. Lazar | Interim CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 1,000,000 | 0 | - | - | Series C Convertible Preferred Stock | |
| David E. Lazar | Interim CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2025 | 2,100,000 | 2,100,000 | - | - | Series D Convertible Preferred Stock | |
| David Natan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 100,000 | 100,000 (0%) | 0% | - | Common Stock | |
| Paul McBarron | Director, See Remarks | 21 Dec 2023 | 1,886 | 33,378 (0%) | 0% | 3.3 | 6,252 | Common Stock | |
| Rombotis Spiro | Director, President and CEO | 21 Dec 2023 | 6,070 | 6,070 | - | - | Warrants (right to buy) | ||
| Rombotis Spiro | Director, President and CEO | 21 Dec 2023 | 6,070 | 68,658 (0%) | 0% | 3.3 | 20,122 | Common Stock | |
| McBarron Paul | Director, See Remarks | 21 Dec 2023 | 1,886 | 1,886 | - | - | Warrants (right to buy) | ||
| Christopher S. Henney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 21,219 | 39,415 (0%) | 0% | 0 | Common Stock | |
| Christopher S. Henney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 42,438 | 42,438 | - | - | Stock Option (right to buy) | |
| Paul McBarron | Director, See Remarks | 30 Jun 2023 | 70,200 | 70,200 | - | - | Stock Option (right to buy) | ||
| Spiro Rombotis | Director, President and CEO | 30 Jun 2023 | 110,000 | 110,000 | - | - | Stock Option (right to buy) | ||
| Samuel L. Barker | Director | 30 Jun 2023 | 21,219 | 40,415 (0%) | 0% | 0 | Common Stock | ||
| Samuel L. Barker | Director | 30 Jun 2023 | 42,438 | 42,438 | - | - | Stock Option (right to buy) | ||
| Robert J. Spiegel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 21,219 | 39,415 (0%) | 0% | 0 | Common Stock | |
| Robert J. Spiegel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 42,438 | 42,438 | - | - | Stock Option (right to buy) | |
| Kenneth M. Ferguson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 42,438 | 42,438 | - | - | Stock Option (right to buy) | |
| Kenneth M. Ferguson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 21,219 | 44,952 (0%) | 0% | 0 | Common Stock | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 21,219 | 40,602 (0%) | 0% | 0 | Common Stock | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 42,438 | 42,438 | - | - | Stock Option (right to buy) | |
| Mark Kirschbaum | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 70,200 | 70,200 | - | - | Stock Option (right to buy) | |
| Paul McBarron | Director, See Remarks | 31 Jan 2023 | 31,200 | 31,492 (0%) | 0% | 0 | Common Stock | ||
| Spiro Rombotis | Director, President and CEO | 31 Jan 2023 | 57,600 | 62,588 (0%) | 0% | 0 | Common Stock | ||
| Mark Kirschbaum | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jan 2023 | 31,200 | 31,200 (0%) | 0% | 0 | Common Stock | |
| Christopher S. Henney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 15,822 | 18,196 (0%) | 0% | 0 | Common Stock | |
| Christopher S. Henney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 31,645 | 31,645 | - | - | Stock Option (right to buy) | |
| Lloyd M. Sems | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 31,645 | 31,645 | - | - | Stock Option (right to buy) | |
| Lloyd M. Sems | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 15,822 | 18,196 (0%) | 0% | 0 | Common Stock | |
| Samuel L. Barker | Director | 14 Jun 2022 | 15,822 | 19,196 (0%) | 0% | 0 | Common Stock | ||
| Samuel L. Barker | Director | 14 Jun 2022 | 31,645 | 31,645 | - | - | Stock Option (right to buy) | ||
| Robert J. Spiegel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 15,822 | 18,196 (0%) | 0% | 0 | Common Stock | |
| Robert J. Spiegel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 31,645 | 31,645 | - | - | Stock Option (right to buy) | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 31,645 | 31,645 | - | - | Stock Option (right to buy) | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 15,822 | 19,383 (0%) | 0% | 0 | Common Stock | |
| Paul McBarron | Director, See Remarks | 13 Dec 2021 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | ||
| Spiro Rombotis | Director, President and CEO | 13 Dec 2021 | 190,000 | 190,000 | - | - | Stock Option (right to buy) | ||
| Mark Kirschbaum | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Dec 2021 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Samuel L. Barker | Director | 30 Nov 2021 | 12 | 3,374 (0%) | 0% | 3.6 | 43 | Common Stock | |
| Spiro Rombotis | Director, President and CEO | 18 Nov 2021 | 4,000 | 4,988 (0%) | 0% | 4.5 | 18,000 | Common Stock | |
| Samuel L. Barker | Director | 24 Aug 2021 | 1,000 | 3,386 (0%) | 0% | 5 | 5,000 | Common Stock | |
| Christopher S. Henney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 4,748 | 4,748 | - | - | Stock Option (right to buy) | |
| Christopher S. Henney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,374 | 2,374 (0%) | 0% | 0 | Common Stock | |
| Lloyd M. Sems | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,374 | 2,374 (0%) | 0% | 0 | Common Stock | |
| Lloyd M. Sems | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 4,748 | 4,748 | - | - | Stock Option (right to buy) | |
| Samuel L. Barker | Director | 15 Jun 2021 | 2,374 | 2,386 (0%) | 0% | 0 | Common Stock | ||
| Samuel L. Barker | Director | 15 Jun 2021 | 4,748 | 4,748 | - | - | Stock Option (right to buy) | ||
| Gregory T. Hradsky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 4,748 | 4,748 | - | - | Stock Option (right to buy) | |
| Gregory T. Hradsky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,374 | 2,374 (0%) | 0% | 0 | Common Stock | |
| Robert J. Spiegel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,374 | 2,374 (0%) | 0% | 0 | Common Stock | |
| Robert J. Spiegel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 4,748 | 4,748 | - | - | Stock Option (right to buy) | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,374 | 3,561 (0%) | 0% | 0 | Common Stock | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,374 | 7,122 | - | - | Stock Option (right to buy) | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 4,748 | 7,122 | - | - | Stock Option (right to buy) | |
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 1,187 | 3,561 (0%) | 0% | 0 | Common Stock | |
| Paul McBarron | Director, See Remarks | 11 Dec 2020 | 120,000 | 120,000 | - | - | Stock Option (right to buy) | ||
| Spiro Rombotis | Director, President and CEO | 11 Dec 2020 | 175,000 | 175,000 | - | - | Stock Option (right to buy) | ||
| Karin L. Walker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Nov 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | |
| Mark Kirschbaum | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Oct 2020 | 120,000 | 120,000 | - | - | Stock Option (right to buy) | |
| Christopher S. Henney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | |
| Lloyd M. Sems | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | |
| Samuel L. Barker | Director | 25 Jun 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | ||
| John Banham | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | |
| David C. U'Prichard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | |
| Gregory T. Hradsky | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | |
| Robert J. Spiegel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2020 | 5,200 | 5,200 | - | - | Stock Option (right to buy) | |
| Paul McBarron | Director, E. VP, Fin, CFO and COO | 05 Dec 2019 | 11,980 | 11,980 | - | - | Option | ||
| Paul McBarron | Director, E. VP, Fin, CFO and COO | 05 Dec 2019 | 13,022 | 13,022 | - | - | Option | ||
| Spiro Rombotis | Director, President and CEO | 05 Dec 2019 | 15,625 | 15,625 | - | - | Option | ||
| Spiro Rombotis | Director, President and CEO | 05 Dec 2019 | 15,625 | 15,625 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Dec 2019 | 10,182 | 10,182 | - | - | Option | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Dec 2019 | 11,067 | 11,067 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 18,750 | 18,750 | - | - | Stock Option (right to buy) | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 18,750 | 18,750 | - | - | Stock Option (right to buy) | |
| Samuel L. Barker | None | 29 May 2019 | 18,750 | 18,750 | - | - | Stock Option (right to buy) | ||
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 18,750 | 18,750 | - | - | Stock Option (right to buy) | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 18,750 | 18,750 | - | - | Stock Option (right to buy) | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 18,750 | 18,750 | - | - | Stock Option (right to buy) | |
| Robert J. Spiegel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 May 2019 | 18,750 | 18,750 | - | - | Stock Option (right to buy) | |
| Paul McBarron | Director, E. VP, Fin, CFO and COO | 03 Jan 2019 | 13,021 | 13,021 | - | - | Option | ||
| Paul McBarron | Director, E. VP, Fin, CFO and COO | 03 Jan 2019 | 11,980 | 11,980 | - | - | Option | ||
| Paul McBarron | Director, E. VP, Fin, CFO and COO | 03 Jan 2019 | 270,079 | 270,079 | - | - | Option | ||
| Spiro Rombotis | Director, President and CEO | 03 Jan 2019 | 15,625 | 15,625 | - | - | Option | ||
| Spiro Rombotis | Director, President and CEO | 03 Jan 2019 | 508,198 | 508,198 | - | - | Option | ||
| Spiro Rombotis | Director, President and CEO | 03 Jan 2019 | 14,375 | 14,375 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2019 | 11,068 | 11,068 | - | - | Option | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2019 | 10,183 | 10,183 | - | - | Option | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2019 | 284,592 | 284,592 | - | - | Option | |
| Robert J. Spiegel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Sep 2018 | 8,576 | 8,576 | - | - | Stock Option (right to buy) | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2018 | 8,576 | 8,576 | - | - | Stock Option (right to buy) | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2018 | 8,576 | 8,576 | - | - | Stock Option (right to buy) | |
| Samuel L. Barker | None | 31 May 2018 | 8,576 | 8,576 | - | - | Stock Option (right to buy) | ||
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2018 | 8,576 | 8,576 | - | - | Stock Option (right to buy) | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2018 | 8,576 | 8,576 | - | - | Stock Option (right to buy) | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2018 | 8,576 | 8,576 | - | - | Stock Option (right to buy) | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 May 2017 | 2,000 | 2,000 | - | - | Stock Option (right to buy) | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 May 2017 | 2,000 | 2,000 | - | - | Stock Option (right to buy) | |
| Samuel L. Barker | None | 30 May 2017 | 2,000 | 2,000 | - | - | Stock Option (right to buy) | ||
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 May 2017 | 2,000 | 2,000 | - | - | Stock Option (right to buy) | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 May 2017 | 2,000 | 2,000 | - | - | Stock Option (right to buy) | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 May 2017 | 2,000 | 2,000 | - | - | Stock Option (right to buy) | |
| Kevin C. Tang | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 4.34 per share. | 23 Feb 2017 | 134,200 | 559,900 (13%) | 3% | 4.3 | 582,079 | Common Stock |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2016 | 15,000 | 15,000 | - | - | Option | |
| Samuel L. Barker | None | 26 May 2016 | 15,000 | 15,000 | - | - | Option | ||
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2016 | 15,000 | 15,000 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2016 | 15,000 | 15,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2016 | 15,000 | 15,000 | - | - | Option | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2016 | 15,000 | 15,000 | - | - | Option | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2016 | 15,000 | 15,000 | - | - | Option | |
| Paul McBarron | Director, E.V.P., Fin, C.F.O. & C.O.O. | 07 Dec 2015 | 260,432 | 260,432 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 07 Dec 2015 | 437,569 | 437,569 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Dec 2015 | 229,858 | 229,858 | - | - | Option | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2015 | 15,000 | 15,000 | - | - | Option | |
| Samuel L. Barker | None | 22 May 2015 | 15,000 | 15,000 | - | - | Option | ||
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2015 | 15,000 | 15,000 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2015 | 15,000 | 15,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2015 | 15,000 | 15,000 | - | - | Option | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2015 | 15,000 | 15,000 | - | - | Option | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2015 | 15,000 | 15,000 | - | - | Option | |
| Paul McBarron | Director, E.V.P.,Finance,C.F.O. & C.O.O. | 18 Feb 2015 | 53,095 | 53,095 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 18 Feb 2015 | 81,742 | 81,742 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2015 | 42,940 | 42,940 | - | - | Option | |
| Spiro Rombotis | Director, President & CEO | 31 Dec 2014 | 3,891 | 237,525 | - | - | Common Stock, $0.001 par value per share | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 31 Dec 2014 | 3,112 | 58,008 | - | - | Common Stock, $0.001 par value per share | |
| Samuel L. Barker | None | 20 Nov 2014 | 3,100 | 3,100 | - | - | Common Stock, $0.001 par value per share | ||
| Samuel L. Barker | None | 10 Sep 2014 | 9,000 | 9,000 | - | - | Option | ||
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2014 | 9,000 | 9,000 | - | - | Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2014 | 9,000 | 9,000 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2014 | 9,000 | 9,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2014 | 9,000 | 9,000 | - | - | Option | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2014 | 9,000 | 9,000 | - | - | Option | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2014 | 9,000 | 9,000 | - | - | Option | |
| Paul McBarron | Director, E.V.P.,Finance,C.F.O. & C.O.O. | 09 Dec 2013 | 70,000 | 70,000 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 09 Dec 2013 | 105,000 | 105,000 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2013 | 65,000 | 65,000 | - | - | Option | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2013 | 5,000 | 5,000 | - | - | Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2013 | 7,142 | 7,142 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2013 | 3,571 | 3,571 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2013 | 7,142 | 7,142 | - | - | Option | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2013 | 3,571 | 3,571 | - | - | Option | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 May 2013 | 3,571 | 3,571 | - | - | Option | |
| Paul McBarron | Director, EVP, Finance, CFO, COO | 21 May 2013 | 8,333 | 65,481 | - | - | Common Stock, $0.001 par value per share | ||
| Paul McBarron | Director, EVP, Finance, CFO, COO | 21 May 2013 | 4,615 | 70,096 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 21 May 2013 | 100,000 | 268,292 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 21 May 2013 | 100,000 | 241,416 | - | - | Common Stock, $0.001 par value per share | ||
| Lloyd M. Sems | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 May 2013 | 33,333 | 33,333 | - | - | Common Stock, $0.001 par value per share | |
| Paul McBarron | Director, EVP, Finance, CFO, COO | 25 Jan 2013 | 6,712 | 75,433 | - | - | Common Stock, $0.001 par value per share | ||
| Paul McBarron | Director, EVP, Finance, CFO, COO | 25 Jan 2013 | 20,000 | 68,721 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & CEO | 25 Jan 2013 | 10,791 | 168,292 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & CEO | 25 Jan 2013 | 20,000 | 157,501 | - | - | Common Stock, $0.001 par value per share | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2013 | 5,668 | 44,692 | - | - | Common Stock, $0.001 par value per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2013 | 20,000 | 39,024 | - | - | Common Stock, $0.001 par value per share | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2012 | 25,000 | 25,000 | - | - | Option | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2012 | 35,000 | 35,000 | - | - | Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2012 | 50,000 | 50,000 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2012 | 25,000 | 25,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2012 | 50,000 | 50,000 | - | - | Option | |
| Lloyd M. Sems | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2012 | 25,000 | 25,000 | - | - | Option | |
| Gregory T. Hradsky | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2012 | 25,000 | 25,000 | - | - | Option | |
| Spiro Rombotis | Director, President & C.E.O. | 22 Dec 2011 | 15,902 | 746,516 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 22 Dec 2011 | 75,000 | 730,614 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 22 Dec 2011 | 75,000 | 0 | - | - | Option | ||
| Paul McBarron | Director, EVP, Finance, CFO, COO | 06 Dec 2011 | 75,000 | 263,054 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 06 Dec 2011 | 75,000 | 655,614 | - | - | Common Stock, $0.001 par value per share | ||
| Judy Chiao | V.P., Clin. Dev. & reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2011 | 60,000 | 133,168 | - | - | Common Stock, $0.001 par value per share | |
| Robert Sosnowski | VP, Marketing & Sales | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2011 | 28,000 | 28,000 | - | - | Common Stock, $0.001 par value per share | |
| Paul McBarron | Director, EVP, Finance, CFO, COO | 23 Sep 2011 | 12,000 | 188,054 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President and C.E.O. | 22 Sep 2011 | 5,000 | 584,430 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President and C.E.O. | 22 Sep 2011 | 24,100 | 608,530 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President and C.E.O. | 22 Sep 2011 | 1,200 | 1,600 | - | - | Preferred Convertible Exchangeable Stock 6% | ||
| Marxe W Austin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 22 Sep 2011 | 500,000 | 3,456,900 | - | - | Common Stock | |
| Marxe W Austin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 22 Sep 2011 | 650,000 | 2,806,900 | - | - | Common Stock | |
| Spiro Rombotis | Director, President & C.E.O. | 13 Sep 2011 | 12,000 | 579,430 | - | - | Common Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 13 Sep 2011 | 400 | 400 | - | - | Preferred Stock, $0.001 par value per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 22 Aug 2011 | 9,232 | 567,430 | - | - | Common Stock, $0.001 par value per share | ||
| Marxe W Austin | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 07 Jul 2011 | 2,053,450 | 0 | - | - | Options | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2011 | 25,000 | 25,000 | - | - | Option | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2011 | 35,000 | 35,000 | - | - | Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2011 | 50,000 | 50,000 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2011 | 25,000 | 25,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2011 | 50,000 | 50,000 | - | - | Option | |
| Marxe W Austin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 May 2011 | 100,000 | 4,006,900 | - | - | Common Stock | |
| Marxe W Austin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 May 2011 | 50,000 | 3,956,900 | - | - | Common Stock | |
| Paul McBarron | Director, EVP, Finance, CFO, COO | 10 Dec 2010 | 75,000 | 75,000 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 10 Dec 2010 | 75,000 | 75,000 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2010 | 62,500 | 62,500 | - | - | Option | |
| Robert Sosnowski | VP, Marketing & Sales | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Dec 2010 | 40,000 | 40,000 | - | - | Option | |
| Marxe W Austin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 30 Nov 2010 | 142,000 | 4,106,900 | - | - | Common Stock | |
| Marxe W Austin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 26 Nov 2010 | 58,000 | 4,248,900 | - | - | Common Stock | |
| Marxe W Austin | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Oct 2010 | 183,982 | 4,306,900 | - | - | Common Stock | |
| Robert Sosnowski | VP, Sales & Marketing | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 May 2010 | 10,000 | 10,000 | - | - | Common Stock, $0.001 par value per share | |
| Robert Sosnowski | VP, Sales & Marketing | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 May 2010 | 10,000 | 0 | - | - | Common Stock, $0.001 par value per share | |
| Robert Sosnowski | VP, Sales & Marketing | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 May 2010 | 10,000 | 90,000 | - | - | Option | |
| Spiro Rombotis | Director, President & C.E.O. | 23 Apr 2010 | 8,350 | 483,198 | - | - | Common Stock, $0.001 par value per share | ||
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2010 | 25,000 | 25,000 | - | - | Option | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2010 | 35,000 | 35,000 | - | - | Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2010 | 50,000 | 50,000 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2010 | 25,000 | 25,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Mar 2010 | 50,000 | 50,000 | - | - | Option | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Mar 2009 | 25,000 | 25,000 | - | - | Option | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Mar 2009 | 35,000 | 35,000 | - | - | Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Mar 2009 | 50,000 | 50,000 | - | - | Option | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Mar 2009 | 25,000 | 25,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Mar 2009 | 50,000 | 50,000 | - | - | Option | |
| Spiro Rombotis | Director, President & C.E.O. | 02 Dec 2008 | 3,000 | 441,548 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 19 Nov 2008 | 8,000 | 437,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 19 Nov 2008 | 900 | 438,548 | - | - | Common Stock, par value $0.001 per share | ||
| Paul McBarron | Director, E.V.P., Finance & C.O.O. | 18 Nov 2008 | 50,000 | 126,054 | - | - | Common Stock, par value $0.001 per share | ||
| Paul McBarron | Director, E.V.P., Finance & C.O.O. | 18 Nov 2008 | 150,000 | 150,000 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 18 Nov 2008 | 150,000 | 150,000 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 18 Nov 2008 | 50,000 | 50,000 | - | - | Restricted Stock Units | ||
| Spiro Rombotis | Director, President & C.E.O. | 18 Nov 2008 | 50,000 | 479,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 18 Nov 2008 | 150,000 | 150,000 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2008 | 25,000 | 73,168 | - | - | Common Stock, $0.001 par value per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2008 | 75,000 | 75,000 | - | - | Option | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2008 | 50,000 | 50,000 | - | - | Option | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2008 | 16,700 | 16,700 | - | - | Restricted Stock Units | |
| Robert Sosnowski | VP, Marketing & Sales | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2008 | 100,000 | 100,000 | - | - | Option | |
| Robert Sosnowski | VP, Marketing & Sales | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2008 | 16,700 | 16,700 | - | - | Restricted Stock Units | |
| Robert Sosnowski | VP, Marketing & Sales | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2008 | 100,000 | 100,000 | - | - | Option | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 356 | 650,538 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 644 | 1,176,810 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 19,033 | 631,505 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 34,431 | 1,142,379 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 71,200 | 560,305 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 128,800 | 1,013,579 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 56,957 | 503,348 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 18 Nov 2008 | 131,836 | 881,743 | - | - | Common Stock | |
| Spiro Rombotis | Director, President & C.E.O. | 17 Nov 2008 | 2,000 | 412,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 17 Nov 2008 | 17,000 | 429,648 | - | - | Common Stock, par value $0.001 per share | ||
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Nov 2008 | 45,781 | 711,281 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Nov 2008 | 82,819 | 1,286,697 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Nov 2008 | 47,465 | 663,816 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Nov 2008 | 85,865 | 1,200,832 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Nov 2008 | 12,922 | 650,894 | - | - | Common Stock | |
| Flynn E James | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 13 Nov 2008 | 23,378 | 1,177,454 | - | - | Common Stock | |
| Nicholas G. Bacopoulos | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Sep 2008 | 25,000 | 25,000 | - | - | Option | |
| Spiro Rombotis | Director, President & C.E.O. | 18 Aug 2008 | 100 | 401,748 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 18 Aug 2008 | 8,900 | 410,648 | - | - | Common Stock, par value $0.001 per share | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2008 | 100 | 46,268 | - | - | Common Stock, par value $0.001 per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2008 | 100 | 46,368 | - | - | Common Stock, par value $0.001 per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2008 | 400 | 46,768 | - | - | Common Stock, par value $0.001 per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2008 | 362 | 47,130 | - | - | Common Stock, par value $0.001 per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2008 | 38 | 47,168 | - | - | Common Stock, par value $0.001 per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2008 | 1,000 | 48,168 | - | - | Common Stock, par value $0.001 per share | |
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Jun 2008 | 4,700 | 25,006 | - | - | Common Stock, par value $0.001 per share | |
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 Jun 2008 | 300 | 25,306 | - | - | Common Stock, par value $0.001 per share | |
| Spiro Rombotis | Director, President & C.E.O. | 04 Jun 2008 | 5,000 | 396,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 04 Jun 2008 | 5,000 | 401,648 | - | - | Common Stock, par value $0.001 per share | ||
| Paul McBarron | Director, E.V.P., Finance & C.O.O. | 22 May 2008 | 1,950 | 76,054 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 20 May 2008 | 5,000 | 384,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 20 May 2008 | 7,500 | 391,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 14 May 2008 | 10,000 | 374,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 14 May 2008 | 5,000 | 379,648 | - | - | Common Stock, par value $0.001 per share | ||
| Collins William | General Manager | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2008 | 10,000 | 10,000 | - | - | Option | |
| Spiro Rombotis | Director, President & C.E.O. | 19 Mar 2008 | 2,600 | 364,648 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 19 Mar 2008 | 3,200 | 362,048 | - | - | Common Stock, par value $0.001 per share | ||
| John Francis Womelsdorf | VP, Business Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 18 Mar 2008 | 2,900 | 5,000 | - | - | Common Stock, par value $0.001 per share | |
| John Francis Womelsdorf | VP, Business Development | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 18 Mar 2008 | 2,100 | 2,100 | - | - | Common Stock, par value $0.001 per share | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2008 | 25,000 | 25,000 | - | - | Option | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2008 | 25,000 | 25,000 | - | - | Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2008 | 50,000 | 50,000 | - | - | Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2008 | 50,000 | 50,000 | - | - | Option | |
| Gordon McVie | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2008 | 25,000 | 25,000 | - | - | Option | |
| Pierre Legault | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Feb 2008 | 35,000 | 35,000 | - | - | Option | |
| Gregory Reyes | Senior VP, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Dec 2007 | 25,000 | 25,000 | - | - | Options | |
| Gregory Reyes | Senior VP, Research | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Dec 2007 | 3,000 | 3,000 | - | - | Common Stock, par value $0.001 per share | |
| Spiro Rombotis | Director, President & C.E.O. | 19 Dec 2007 | 1,400 | 357,848 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 19 Dec 2007 | 1,000 | 358,848 | - | - | Common Stock, par value $0.001 per share | ||
| Paul McBarron | Director, E.V.P., Finance & C.O.O. | 06 Dec 2007 | 100,000 | 100,000 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 06 Dec 2007 | 200,000 | 200,000 | - | - | Option | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2007 | 100,000 | 100,000 | - | - | Option | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2007 | 50,000 | 50,000 | - | - | Option | |
| Gregory Reyes | Senior VP, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2007 | 25,000 | 25,000 | - | - | Options | |
| Collins William | General Manager | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Oct 2007 | 35,000 | 35,000 | - | - | Option | |
| Gregory Reyes | Senior VP, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2007 | 55,000 | 55,000 | - | - | Options | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2007 | 31,250 | 31,250 | - | - | Options | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2007 | 33,750 | 33,750 | - | - | Options | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2007 | 62,500 | 62,500 | - | - | Options | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2007 | 62,500 | 62,500 | - | - | Options | |
| Gordon McVie | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2007 | 31,250 | 31,250 | - | - | Options | |
| Pierre Legault | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Mar 2007 | 35,000 | 35,000 | - | - | Options | |
| Paul McBarron | Director, E.V.P., Finance & C.O.O. | 21 Dec 2006 | 100,000 | 100,000 | - | - | Option | ||
| Spiro Rombotis | Director, President & C.E.O. | 21 Dec 2006 | 160,000 | 160,000 | - | - | Options | ||
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Dec 2006 | 80,000 | 80,000 | - | - | Option | |
| Robert Westwood | V.P., Chem. & Preclin. Dev. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Dec 2006 | 50,000 | 50,000 | - | - | Option | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Dec 2006 | 50,000 | 50,000 | - | - | Option | |
| Jean Deleage | Other | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 01 Dec 2006 | 114,239 | 0 | - | - | Common Stock | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Oct 2006 | 8,333 | 25,000 | - | - | Option | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Oct 2006 | 40,000 | 40,000 | - | - | Option | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2006 | 8,333 | 16,667 | - | - | Option | |
| Spiro Rombotis | Director, President & C.E.O. | 14 Sep 2006 | 100 | 355,148 | - | - | Common Stock | ||
| Spiro Rombotis | Director, President & C.E.O. | 14 Sep 2006 | 1,300 | 356,448 | - | - | Common Stock | ||
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Sep 2006 | 320 | 19,666 | - | - | Common Stock | |
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Sep 2006 | 320 | 19,986 | - | - | Common Stock | |
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Sep 2006 | 320 | 20,306 | - | - | Common Stock | |
| Spiro Rombotis | Director, President & C.E.O. | 12 Sep 2006 | 100 | 355,048 | - | - | Common Stock | ||
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 08 Sep 2006 | 250 | 19,026 | - | - | Common Stock | |
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 08 Sep 2006 | 320 | 19,346 | - | - | Common Stock | |
| Spiro Rombotis | Director, President & C.E.O. | 08 Sep 2006 | 300 | 354,848 | - | - | Common Stock | ||
| Spiro Rombotis | Director, President & C.E.O. | 08 Sep 2006 | 100 | 354,948 | - | - | Common Stock | ||
| John Banham | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Sep 2006 | 3,500 | 36,847 | - | - | Common Stock | |
| David C. U'Prichard | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Sep 2006 | 250 | 18,776 | - | - | Common Stock | |
| Spiro Rombotis | Director, President & C.E.O. | 06 Sep 2006 | 300 | 354,248 | - | - | Common Stock | ||
| Spiro Rombotis | Director, President & C.E.O. | 06 Sep 2006 | 300 | 354,548 | - | - | Common Stock | ||
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Sep 2006 | 8,334 | 8,334 | - | - | Option | |
| John Francis Womelsdorf | VP, Business Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Sep 2006 | 8,334 | 8,334 | - | - | Option | |
| John Banham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 18,750 | 18,750 | - | - | Common Stock Option | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 26 | 26,250 | - | - | Common Stock Option | |
| David C. U'Prichard | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 37,500 | 37,500 | - | - | Common Stock Option | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 37,500 | 37,500 | - | - | Common Stock Option | |
| Paul McBarron | Director, E.V.P., Finance & C.O.O. | 14 Jun 2006 | 63,680 | 63,680 | - | - | Common Stock Option | ||
| Gordon McVie | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 18,750 | 18,750 | - | - | Common Stock Option | |
| Spiro Rombotis | Director, President & C.E.O. | 14 Jun 2006 | 97,834 | 97,834 | - | - | Common Stock Option | ||
| Robert Jackson | S.V.P. & Chief Scientific Offi | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 63,606 | 63,606 | - | - | Common Stock Option | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 48,967 | 48,967 | - | - | Common Stock Option | |
| Robert Westwood | V.P., Chem. & Preclin. Dev. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2006 | 49,144 | 49,144 | - | - | Common Stock Option | |
| Spiro Rombotis | Director, President & C.E.O. | 17 Apr 2006 | 100 | 353,948 | - | - | Common Stock | ||
| John Banham | None | Other type of transaction at price $ 0.00 per share. | 27 Mar 2006 | 33,347 | 33,347 | - | - | Common Stock, par value $0.001 per share | |
| David C. U'Prichard | None | Other type of transaction at price $ 0.00 per share. | 27 Mar 2006 | 18,526 | 18,526 | - | - | Common Stock, par value $0.001 per share | |
| Paul McBarron | Director, E.V.P., Finance & C.O.O. | 27 Mar 2006 | 74,104 | 74,104 | - | - | Common Stock, par value $0.001 per share | ||
| Spiro Rombotis | Director, President & C.E.O. | 27 Mar 2006 | 353,848 | 353,848 | - | - | Common Stock, par value $0.001 per share | ||
| Robert Jackson | S.V.P. & Chief Scientific Offi | Other type of transaction at price $ 0.00 per share. | 27 Mar 2006 | 64,841 | 64,841 | - | - | Common Stock, par value $0.001 per share | |
| Judy Chiao | V.P., Clin. Dev. & Reg. Aff. | Other type of transaction at price $ 0.00 per share. | 27 Mar 2006 | 48,168 | 46,168 | - | - | Common Stock, par value $0.001 per share | |
| Robert T. Nelsen | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 10,000 | 10,000 | - | - | Stock Option (Right To Buy) | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 10,000 | 10,000 | - | - | Director (Stock Option Right to Buy) | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 2,500 | 12,500 | - | - | Director (Stock Option Right to Buy) | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 2,500 | 15,000 | - | - | Director (Stock Option Right to Buy) | |
| Stephen N. Wertheimer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 10,000 | 10,000 | - | - | Director (Stock Option Right to Buy) | |
| Stephen N. Wertheimer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 2,500 | 12,500 | - | - | Director (Stock Option Right to Buy) | |
| Jean Deleage | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 10,000 | 10,000 | - | - | Director (Stock Option Right to Buy) | |
| Jean Deleage | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 2,500 | 12,500 | - | - | Director (Stock Option Right to Buy) | |
| Peter Langecker | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 10,000 | 10,000 | - | - | Director (Stock Option Right to Buy) | |
| Peter Langecker | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 2,500 | 12,500 | - | - | Director (Stock Option Right to Buy) | |
| Peter Langecker | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 2,500 | 15,000 | - | - | Director (Stock Option Right to Buy) | |
| Robert M. Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2005 | 10,000 | 10,000 | - | - | Director (Stock Option Right to Buy) | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Mar 2005 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| Christopher S. Henney | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Mar 2005 | 200,000 | 200,000 | - | - | Director Stock Option (Right to Buy) | |
| Peter Langecker | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Feb 2005 | 3,000 | 5,000 | - | - | Common | |
| Robert L. Kirkman | Chief Business Officer and VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 40,000 | 40,000 | - | - | Employee Stock Option (Right to Buy) | |
| Ronald J. Berenson | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 100,000 | 100,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mark Frohlich | Medical Director and VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 20,000 | 20,000 | - | - | Employee Stock Option (Right to Buy) | |
| Steve Pegg | SVP Finance, Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 20,000 | 20,000 | - | - | Employee Stock Option (Right to Buy) | |
| Stewart Craig | COO and VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 40,000 | 40,000 | - | - | Employee Stock Option (Right to Buy) | |
| Bonyhadi L Mark | Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 25,000 | 25,000 | - | - | Employee Stock Option (Right to Buy) | |
| Black S Joanna | VP and General Counsel, Secret | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 12,500 | 12,500 | - | - | Employee Stock Option (Right to Buy) | |
| Romel A Lawrence | VP Clinical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2005 | 5,000 | 5,000 | - | - | Employee Stock Option (Right to Buy) | |
| Robert M. Williams | None | Gift of securities by or to the insider at price $ 0.00 per share. | 15 Dec 2004 | 1,156 | 45,700 | - | - | Common | |
| Robert L. Kirkman | Chief Business Officer and VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 40,000 | 40,000 | - | - | Employee Stock Option (Right to Buy) | |
| Ronald J. Berenson | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 100,000 | 100,000 | - | - | Employee Stock Option (Right to Buy) | |
| Mark Frohlich | Medical Director and VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 20,000 | 20,000 | - | - | Employee Stock Option (Right to Buy) | |
| Steve Pegg | SVP Finance, Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 20,000 | 20,000 | - | - | Employee Stock Option (Right to Buy) | |
| Stewart Craig | COO and VP | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 40,000 | 40,000 | - | - | Employee Stock Option (Right to Buy) | |
| Bonyhadi L Mark | Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 25,000 | 25,000 | - | - | Employee Stock Option (Right to Buy) | |
| Black S Joanna | VP and General Counsel, Secret | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 12,500 | 12,500 | - | - | Employee Stock Option (Right to Buy) | |
| Romel A Lawrence | VP Clinical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2004 | 5,000 | 5,000 | - | - | Employee Stock Option (Right to Buy) | |
| Stephen N. Wertheimer | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Nov 2004 | 103,500 | 103,500 | - | - | 6% Convertible Exchangeable Preferred Stock | |
| Jean Deleage | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Nov 2004 | 97,766 | 97,766 | - | - | 6% Convertible Exchangeable Preferred Stock | |
| Jean Deleage | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Nov 2004 | 2,234 | 2,234 | - | - | 6% Convertible Exchangeable Preferered Stock | |
| Robert T. Nelsen | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Oct 2004 | 200,000 | 851,060 | - | - | 6% Convertible Exchangeable Preferred Stock | |
| Keith L. Crandell | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Oct 2004 | 200,000 | 851,060 | - | - | 6% Convertible Exchangeable Preferred Stock | |
| Steven B. Lazarus | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Oct 2004 | 200,000 | 851,060 | - | - | 6% Convertible Exchangeable Preferred Stock | |
| Clinton Bybee | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Oct 2004 | 200,000 | 851,060 | - | - | 6% Convertible Exchangeable Preferred Stock | |
| Daniel K. Spiegelman | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Sep 2004 | 10,000 | 10,000 | - | - | Director Stock Option (Right to Buy) | |
| Romel A Lawrence | VP Clinical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2004 | 30,000 | 30,000 | - | - | Employee Stock Option (Right to Buy) | |
| Peter Langecker | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jun 2004 | 1,000 | 1,000 | - | - | Common | |
| Peter Langecker | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jun 2004 | 1,000 | 2,000 | - | - | Common | |
| Ronald J. Berenson | Director, President & C.E.O. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Apr 2004 | 27,272 | 430,939 | - | - | Common Stock | |
| Ronald J. Berenson | Director, President & C.E.O. | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Apr 2004 | 27,272 | 0 | - | - | Employee Stock Option (right to buy) | |
| Robert L. Kirkman | Chief Business Officer & V.P. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Apr 2004 | 40,000 | 40,000 | - | - | Employee Stock Option (right to buy) | |
| Ronald J. Berenson | Director, President & C.E.O. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Apr 2004 | 45,000 | 45,000 | - | - | Employee Stock Option (right to buy) | |
| Mark Frohlich | Medical Director and V.P. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Apr 2004 | 15,000 | 15,000 | - | - | Employee Stock Option (right to buy) | |
| Steve Pegg | S.V.P. of Finance & Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Apr 2004 | 20,000 | 20,000 | - | - | Employee Stock Option (right to buy) | |
| Stewart Craig | C.O.O. & Vice President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Apr 2004 | 20,000 | 20,000 | - | - | Employees Stock Option (right to buy) | |
| Bonyhadi L Mark | V.P , Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Apr 2004 | 5,000 | 5,000 | - | - | Employee Stock Option (right to buy) | |
| Black S Joanna | General Counsel, V.P. & Sec. | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Apr 2004 | 15,000 | 15,000 | - | - | Employee Stock Option (right to buy) | |
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 354,837 | 0 | - | - | 6% Convertible Promissory Notes | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 899,104 | 0 | - | - | Series F Convertible Preferred Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 89,002 | 0 | - | - | Warrants to purchase Common Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 1,866,771 | 1,866,771 | - | - | Common Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Mar 2004 | 187,500 | 2,054,271 | - | - | Common Stock | |
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 789,469 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 2,045,454 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 1,119,265 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 1,321,942 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 935,251 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 50,237 | 0 | - | - | Warrants to purchase Series A Convertible Preferred | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 26,918 | 0 | - | - | Warrants to purchase Common Stock | ||
| Robert T. Nelsen | Director, Ten Percent Owner | 19 Mar 2004 | 92,580 | 0 | - | - | Warrants to purchase Common Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 1,119,265 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 1,321,942 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 935,251 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 50,237 | 0 | - | - | Warrants to purchase Series A Convertible Preferred Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 26,918 | 0 | - | - | Warrants to purchase Common Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 92,580 | 0 | - | - | Warrants to purchase Common Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 354,837 | 0 | - | - | 6% Convertible Promissory Notes | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 899,104 | 0 | - | - | Series F Convertible Preferred Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 89,002 | 0 | - | - | Warrants to purchase Common Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 1,866,771 | 1,866,771 | - | - | Common Stock | ||
| Keith L. Crandell | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Mar 2004 | 187,500 | 2,054,271 | - | - | Common Stock | |
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 789,469 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Keith L. Crandell | Ten Percent Owner | 19 Mar 2004 | 2,045,454 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 106,632 | 0 | - | - | Convertible Promissory Note | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 326,620 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 52,004 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 54,836 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 29,649 | 0 | - | - | Common Stock Warrant (Right to Buy) | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 4,622 | 0 | - | - | Common Stock Warrant (Right to Buy) | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 106,632 | 0 | - | - | Common Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 326,620 | 0 | - | - | Common Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 52,004 | 0 | - | - | Common Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 54,836 | 0 | - | - | Common Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 29,649 | 0 | - | - | Common Stock | ||
| Stephen N. Wertheimer | None | 19 Mar 2004 | 4,622 | 574,363 | - | - | Common Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 1,866,771 | 1,866,771 | - | - | Common Stock | ||
| Steven B. Lazarus | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Mar 2004 | 187,500 | 2,054,271 | - | - | Common Stock | |
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 789,469 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 2,045,454 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 1,119,265 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 1,321,942 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 935,251 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 50,237 | 0 | - | - | Warrants to purchase Series A Convertible Preferred Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 26,918 | 0 | - | - | Warrants to purchase Common Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 92,580 | 0 | - | - | Warrants to purchase Common Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 354,837 | 0 | - | - | 6% Convertible Promissory Notes | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 899,104 | 0 | - | - | Series F Convertible Preferred Stock | ||
| Steven B. Lazarus | Ten Percent Owner | 19 Mar 2004 | 89,002 | 0 | - | - | Warrants to purchase Common Stock | ||
| Jean Deleage | None | 19 Mar 2004 | 1,894,737 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Jean Deleage | None | 19 Mar 2004 | 805,281 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Jean Deleage | None | 19 Mar 2004 | 971,331 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Jean Deleage | None | 19 Mar 2004 | 584,547 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Jean Deleage | None | 19 Mar 2004 | 359,712 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Jean Deleage | None | 19 Mar 2004 | 261,312 | 0 | - | - | Common Stock Warrants (right to buy) | ||
| Jean Deleage | None | 19 Mar 2004 | 261,312 | 0 | - | - | Preferred Stock Warrants (right to buy) | ||
| Jean Deleage | None | 19 Mar 2004 | 261,312 | 0 | - | - | 6% Convertible Promissory Note | ||
| Jean Deleage | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Mar 2004 | 125,000 | 0 | - | - | Common Stock | |
| Jean Deleage | None | 19 Mar 2004 | 1,017,400 | 1,142,400 | - | - | Common Stock | ||
| Ronald J. Berenson | Director, President & C.E.O. | 19 Mar 2004 | 10,526 | 403,667 | - | - | Common Stock | ||
| Ronald J. Berenson | Director, President & C.E.O. | 19 Mar 2004 | 10,526 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 10,670 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 478,466 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 99,172 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 207,805 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 58,861 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 64,741 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 660 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 35,360 | 0 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 5,229 | 960,964 | - | - | Common Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 10,670 | 0 | - | - | Convertible Promissory Note | ||
| Robert E. Curry | None | 19 Mar 2004 | 478,466 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 99,172 | 0 | - | - | Series B Convertible Preeferred Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 207,805 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 58,861 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 64,741 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 660 | 0 | - | - | Series F Convertible Preferred Stock | ||
| Robert E. Curry | None | 19 Mar 2004 | 35,360 | 0 | - | - | Common Stock Warrant (Right to Buy) | ||
| Robert E. Curry | None | 19 Mar 2004 | 5,229 | 0 | - | - | Common Stock Warrant (Right to Buy) | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 26,918 | 0 | - | - | Warrants to purchase Common Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 92,580 | 0 | - | - | Warrants to purchase Common Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 354,837 | 0 | - | - | 6% Convertible Promissory Notes | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 899,104 | 0 | - | - | Series F Convertible Preferred Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 89,002 | 0 | - | - | Warrants to purchase Common Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 1,866,771 | 1,866,771 | - | - | Common Stock | ||
| Clinton Bybee | Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 19 Mar 2004 | 187,500 | 2,054,271 | - | - | Common Stock | |
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 789,469 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 2,045,454 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 1,119,265 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 1,321,942 | 0 | - | - | Series D Convertible Preferred Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 935,251 | 0 | - | - | Series E Convertible Preferred Stock | ||
| Clinton Bybee | Ten Percent Owner | 19 Mar 2004 | 50,237 | 0 | - | - | Warrants to purchase Series A Convertible Preferred Stock |