564.9K XNAS Volume
XNAS 19 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Lea Leiv | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Dec 2024 | 300,000 | 300,000 | - | - | Stock Option (Right to Buy) | |
| Arcara Jeffrey | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Dec 2024 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Dec 2024 | 750,000 | 750,000 | - | - | Stock Option (Right to Buy) | |
| Jones William Benton | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Dec 2024 | 300,000 | 300,000 | - | - | Stock Option (Right to Buy) | |
| Ian T. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2024 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 10 May 2024 | 302,016 | 1,188,103 (3%) | 0% | 0 | Common Stock | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.73 per share. | 06 May 2024 | 577,634 | 577,634 (1%) | 1% | 1.7 | 1,000,000 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 May 2024 | 559,073 | 559,073 | - | - | Warrant (Right to Buy) | |
| William Benton Jones | See Remarks | Purchase of securities on an exchange or from another person at price $ 1.73 per share. | 06 May 2024 | 20,000 | 153,773 (0%) | 0% | 1.7 | 34,624 | Common Stock |
| William Benton Jones | See Remarks | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 May 2024 | 19,357 | 19,357 | - | - | Warrant (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 May 2024 | 1,444,085 | 1,444,085 | - | - | Pre-Funded Warrants (right to buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 May 2024 | 1,397,684 | 1,397,684 | - | - | Common Warrants (right to buy) | |
| Jeffrey Arcara | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2024 | 400,000 | 400,000 | - | - | Stock Option (Right to Buy) | |
| Lea Leiv | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| A. Miller Richard | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 500,000 | 500,000 | - | - | Stock Option (Right to Buy) | |
| Gould P. Elisha | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| T. Ian Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| P. Edith Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott Morrison W. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| S. Grais Linda | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Dec 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Ian T. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Edith P. Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | Director | Purchase of securities on an exchange or from another person at price $ 2.45 per share. | 15 May 2023 | 10,000 | 10,000 (0%) | 0% | 2.5 | 24,500 | Common Stock |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 800,000 | 800,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Purchase of securities on an exchange or from another person at price $ 0.79 per share. | 20 Dec 2022 | 20,000 | 133,773 (0%) | 0% | 0.8 | 15,800 | Common Stock |
| Leiv Lea | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.84 per share. | 13 Dec 2022 | 4,000 | 133,238 (0%) | 0% | 0.8 | 3,364 | Common Stock |
| Leiv Lea | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.74 per share. | 13 Dec 2022 | 30,000 | 129,238 (0%) | 0% | 0.7 | 22,275 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.74 per share. | 13 Dec 2022 | 50,000 | 1,480,119 (4%) | 0% | 0.7 | 37,015 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.78 per share. | 13 Dec 2022 | 10,000 | 1,490,119 (4%) | 0% | 0.8 | 7,812 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.76 per share. | 28 Sep 2022 | 25,000 | 1,394,405 (4%) | 0% | 0.8 | 19,070 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.82 per share. | 20 Sep 2022 | 2,700 | 1,364,405 (4%) | 0% | 0.8 | 2,214 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.82 per share. | 20 Sep 2022 | 5,000 | 1,369,405 (4%) | 0% | 0.8 | 4,075 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.81 per share. | 20 Sep 2022 | 12,300 | 1,361,705 (4%) | 0% | 0.8 | 9,964 | Common Stock |
| Ian T. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 320,000 | 320,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Edith P. Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2022 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.00 per share. | 24 Jun 2022 | 5,000 | 1,349,405 (4%) | 0% | 1.0 | 4,985 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.03 per share. | 24 Jun 2022 | 5,000 | 1,344,405 (4%) | 0% | 1.0 | 5,150 | Common Stock |
| Ian T. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Edith P. Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.97 per share. | 02 Jun 2022 | 170 | 1,338,515 (4%) | 0% | 1.0 | 165 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.01 per share. | 02 Jun 2022 | 890 | 1,339,405 (4%) | 0% | 1.0 | 899 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.98 per share. | 02 Jun 2022 | 4,830 | 1,338,345 (4%) | 0% | 1.0 | 4,733 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.64 per share. | 31 Mar 2022 | 15,000 | 1,333,515 (4%) | 0% | 1.6 | 24,534 | Common Stock |
| Leiv Lea | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.54 per share. | 16 Mar 2022 | 35,160 | 85,360 (0%) | 0% | 1.5 | 54,146 | Common Stock |
| Leiv Lea | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 1.65 per share. | 16 Mar 2022 | 13,878 | 99,238 (0%) | 0% | 1.7 | 22,899 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.47 per share. | 15 Mar 2022 | 25,000 | 1,313,515 (4%) | 0% | 1.5 | 36,650 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.59 per share. | 15 Mar 2022 | 5,000 | 1,318,515 (4%) | 0% | 1.6 | 7,950 | Common Stock |
| Peter A. Thompson | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.09 per share. | 20 Sep 2021 | 1,109,644 | 6,943,654 (22%) | 3% | 6.1 | 6,757,732 | Common Stock, $0.0001 par value |
| Ian T. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 320,000 | 320,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Edith P. Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Sep 2021 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 1.93 per share. | 20 Aug 2021 | 10,000 | 1,288,515 (4%) | 0% | 1.9 | 19,254 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 2.80 per share. | 04 May 2021 | 35,714 | 35,714 (0%) | 0% | 2.8 | 99,999 | Common Stock |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.50 per share. | 17 Feb 2021 | 1,285,714 | 8,053,298 (26%) | 4% | 3.5 | 4,499,999 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.50 per share. | 17 Feb 2021 | 100,000 | 1,278,515 (4%) | 0% | 3.5 | 350,000 | Common Stock |
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2020 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2020 | 320,000 | 320,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2020 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Mehrdad Mobasher | SVP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2020 | 85,000 | 85,000 | - | - | Stock Option (Right to Buy) | |
| Edith P. Mitchell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Sep 2020 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Ian T. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Steve E. Krognes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Ian T. Clark | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Steve E. Krognes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Mar 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Joseph J. Buggy | EVP, Discovery Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 320,000 | 320,000 | - | - | Stock Option (Right to Buy) | |
| Erik J. Verner | VP, Chemistry Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Daniel W. Hunt | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 75,000 | 75,000 | - | - | Stock Option (Right to Buy) | |
| Mehrdad Mobasher | VP, Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2019 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 2.90 per share. | 12 Nov 2019 | 272 | 1,163,779 (3%) | 0% | 2.9 | 789 | Common Stock |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.00 per share. | 12 Nov 2019 | 14,736 | 1,178,515 (3%) | 0% | 3.0 | 44,240 | Common Stock |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.51 per share. | 06 Aug 2019 | 142,656 | 6,767,584 (21%) | 0% | 3.5 | 500,723 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.54 per share. | 06 Aug 2019 | 2,500 | 1,163,507 (3%) | 0% | 3.5 | 8,850 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.58 per share. | 06 Aug 2019 | 5,000 | 1,161,007 (3%) | 0% | 3.6 | 17,875 | Common Stock, $0.0001 par value |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.34 per share. | 27 Jun 2019 | 32,923 | 6,000,507 (19%) | 0% | 3.3 | 109,963 | Common Stock, $0.0001 par value |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.91 per share. | 27 Jun 2019 | 59,243 | 6,624,928 (21%) | 0% | 3.9 | 231,640 | Common Stock, $0.0001 par value |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 3.72 per share. | 27 Jun 2019 | 565,178 | 6,565,685 (21%) | 1% | 3.7 | 2,102,462 | Common Stock, $0.0001 par value |
| Ian T. Clark | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2019 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2019 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Linda S. Grais | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2019 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2019 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2019 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Steve E. Krognes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2019 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.52 per share. | 13 Jun 2019 | 343 | 1,144,350 (3%) | 0% | 3.5 | 1,207 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.40 per share. | 13 Jun 2019 | 11,657 | 1,156,007 (3%) | 0% | 3.4 | 39,666 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.67 per share. | 07 Jun 2019 | 6,000 | 1,144,007 (3%) | 0% | 3.7 | 22,020 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.37 per share. | 07 Jun 2019 | 9,212 | 1,138,007 (3%) | 0% | 3.4 | 31,019 | Common Stock, $0.0001 par value |
| Leiv Lea | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 3.38 per share. | 06 Jun 2019 | 10,000 | 50,200 (0%) | 0% | 3.4 | 33,800 | Common Stock, $0.0001 par value |
| Leiv Lea | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 3.56 per share. | 06 Jun 2019 | 15,500 | 40,200 (0%) | 0% | 3.6 | 55,180 | Common Stock, $0.0001 par value |
| Linda S. Grais | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2019 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Mehrdad Mobasher | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2019 | 210,000 | 210,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 3.29 per share. | 27 Dec 2018 | 20,000 | 1,128,795 (3%) | 0% | 3.3 | 65,884 | Common Stock, $0.0001 par value |
| Leiv Lea | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 4.15 per share. | 21 Dec 2018 | 24,700 | 24,700 (0%) | 0% | 4.1 | 102,409 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 4.40 per share. | 20 Dec 2018 | 5,000 | 1,103,795 (3%) | 0% | 4.4 | 22,000 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 4.39 per share. | 20 Dec 2018 | 5,000 | 1,108,795 (3%) | 0% | 4.4 | 21,950 | Common Stock, $0.0001 par value |
| Joseph J. Buggy | EVP Discovery Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2018 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2018 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Dec 2018 | 10,000 | 1,098,795 (3%) | 0% | 0 | Common Stock, $0.0001 par value | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2018 | 250,000 | 250,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Dec 2018 | 10,000 | 1,108,795 (3%) | 0% | 0 | Common Stock, $0.0001 par value | |
| Erik J. Verner | V.P., Chemistry Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2018 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2018 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Daniel W. Hunt | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Dec 2018 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 5.99 per share. | 06 Dec 2018 | 5,000 | 1,118,795 (3%) | 0% | 6.0 | 29,934 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 5.95 per share. | 04 Dec 2018 | 1,502 | 1,113,795 (3%) | 0% | 6.0 | 8,937 | Common Stock, $0.0001 par value |
| Ian T. Clark | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Steve E. Krognes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2018 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 8.50 per share. | 12 Mar 2018 | 588,235 | 5,967,584 (20%) | 2% | 8.5 | 4,999,998 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 8.50 per share. | 12 Mar 2018 | 100,000 | 1,112,293 (3%) | 0% | 8.5 | 850,000 | Common Stock, $0.0001 par value |
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 8.50 per share. | 12 Mar 2018 | 69,864 | 69,864 (0%) | 0% | 8.5 | 593,844 | Common Stock, $0.0001 par value |
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 8.50 per share. | 12 Mar 2018 | 236,128 | 236,128 (0%) | 0% | 8.5 | 2,007,088 | Common Stock, $0.0001 par value |
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 8.50 per share. | 12 Mar 2018 | 67,769 | 67,769 (0%) | 0% | 8.5 | 576,037 | Common Stock, $0.0001 par value |
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 8.50 per share. | 12 Mar 2018 | 126,806 | 126,806 (0%) | 0% | 8.5 | 1,077,851 | Common Stock, $0.0001 par value |
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 8.50 per share. | 12 Mar 2018 | 87,668 | 87,668 (0%) | 0% | 8.5 | 745,178 | Common Stock, $0.0001 par value |
| Joseph J. Buggy | EVP Discovery Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2018 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Dec 2017 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Dec 2017 | 125,000 | 125,000 | - | - | Stock Option (Right to Buy) | |
| Erik J. Verner | V.P., Chemistry Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Dec 2017 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Dec 2017 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Daniel W. Hunt | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Dec 2017 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 10.78 per share. | 20 Nov 2017 | 10,000 | 1,012,293 (4%) | 0% | 10.8 | 107,850 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 9.89 per share. | 09 Jun 2017 | 3,784 | 986,077 (4%) | 0% | 9.9 | 37,424 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 9.75 per share. | 09 Jun 2017 | 2,500 | 999,793 (4%) | 0% | 9.8 | 24,375 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 10.14 per share. | 09 Jun 2017 | 2,500 | 1,002,293 (4%) | 0% | 10.1 | 25,350 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 9.95 per share. | 09 Jun 2017 | 5,000 | 982,293 (4%) | 0% | 10.0 | 49,750 | Common Stock, $0.0001 par value |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 9.82 per share. | 09 Jun 2017 | 11,216 | 997,293 (4%) | 0% | 9.8 | 110,185 | Common Stock, $0.0001 par value |
| Ian T. Clark | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Scott W. Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Steve E. Krognes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2017 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Ian T. Clark | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2017 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Leiv Lea | Chief Financial Officer | 31 Dec 2016 | 48,000 | 151,253 | - | - | Common Stock, $0.0001 par value | ||
| Leiv Lea | Chief Financial Officer | 31 Dec 2016 | 2,047 | 149,206 | - | - | Common Stock, $0.0001 par value | ||
| Richard A. Miller | Director, President and CEO | 31 Dec 2016 | 50,000 | 1,027,293 | - | - | Common Stock, $0.0001 par value | ||
| Richard A. Miller | Director, President and CEO | 31 Dec 2016 | 50,000 | 977,293 | - | - | Common Stock, $0.0001 par value | ||
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Dec 2016 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Dec 2016 | 160,000 | 160,000 | - | - | Stock Option (Right to Buy) | |
| Erik J. Verner | V.P., Chemistry Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Dec 2016 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | VP Pharmaceutical Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Dec 2016 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 Jun 2016 | 100 | 5,378,449 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 Jun 2016 | 900 | 5,379,349 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Jun 2016 | 12,300 | 5,352,266 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Jun 2016 | 26,083 | 5,378,349 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jun 2016 | 10,000 | 5,329,966 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jun 2016 | 5,000 | 5,339,966 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Jun 2016 | 5,000 | 5,334,966 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2016 | 20,000 | 5,319,966 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Jun 2016 | 30,000 | 5,299,966 | - | - | Common Stock, $0.0001 par value | |
| Jason V. Coloma | SVP, Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2016 | 200,000 | 200,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 May 2016 | 4,716 | 5,269,966 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 18 May 2016 | 61 | 5,265,250 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 18 May 2016 | 4,200 | 5,262,650 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 18 May 2016 | 2,539 | 5,265,189 | - | - | Common Stock, $0.0001 par value | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 May 2016 | 300 | 1,077,293 | - | - | Common Stock, $0.0001 par value | |
| Richard A. Miller | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 May 2016 | 30,000 | 1,076,993 | - | - | Common Stock, $0.0001 par value | |
| Leiv Lea | Chief Financial Officer | 29 Mar 2016 | 42,608 | 199,253 | - | - | Common Stock, $0.0001 par value | ||
| Leiv Lea | Chief Financial Officer | 29 Mar 2016 | 42,608 | 0 | - | - | Series A Preferred Stock | ||
| Richard A. Miller | Director, President and CEO | 29 Mar 2016 | 266,310 | 984,538 | - | - | Common Stock, $0.0001 par value | ||
| Richard A. Miller | Director, President and CEO | 29 Mar 2016 | 62,455 | 0 | - | - | Series B Preferred Stock | ||
| Richard A. Miller | Director, President and CEO | 29 Mar 2016 | 62,455 | 1,046,993 | - | - | Common Stock, $0.0001 par value | ||
| Richard A. Miller | Director, President and CEO | 29 Mar 2016 | 266,310 | 0 | - | - | Series A Preferred Stock | ||
| Peter A. Thompson | Director, Ten Percent Owner | 29 Mar 2016 | 3,994,674 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Peter A. Thompson | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Mar 2016 | 550,000 | 5,258,450 | - | - | Common Stock, $0.0001 par value | |
| Peter A. Thompson | Director, Ten Percent Owner | 29 Mar 2016 | 713,776 | 4,708,450 | - | - | Common Stock, $0.0001 par value | ||
| Peter A. Thompson | Director, Ten Percent Owner | 29 Mar 2016 | 713,776 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Peter A. Thompson | Director, Ten Percent Owner | 29 Mar 2016 | 3,994,674 | 3,994,674 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 92,278 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 71,863 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 92,278 | 643,142 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Mar 2016 | 53,239 | 715,361 | - | - | Common Stock, $0.0001 par value | |
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 583,510 | 583,510 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 550,864 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 428,998 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 550,864 | 550,864 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 95,001 | 662,122 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Mar 2016 | 40,272 | 541,133 | - | - | Common Stock, $0.0001 par value | |
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 567,121 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 583,510 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Mar 2016 | 51,712 | 694,854 | - | - | Common Stock, $0.0001 par value | |
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 428,998 | 428,998 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 97,746 | 681,256 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 95,001 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 97,746 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 567,121 | 567,121 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | 29 Mar 2016 | 71,863 | 500,861 | - | - | Common Stock, $0.0001 par value | ||
| Elisha P. Gould | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 Mar 2016 | 54,777 | 736,033 | - | - | Common Stock, $0.0001 par value | |
| Leiv Lea | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2016 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| Richard A. Miller | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2016 | 500,000 | 500,000 | - | - | Stock Option (Right to Buy) | |
| Peter A. Thompson | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2016 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Elisha P. Gould | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2016 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Erik J. Verner | V.P., Chemistry Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2016 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| William Benton Jones | VP Pharmaceutical Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2016 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| Steve E. Krognes | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Mar 2016 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) |