722.6K XNAS Volume
XNAS 18 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Mar 2025 | 1,000 | 10,665 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Mar 2025 | 1,000 | 10,665 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Mar 2025 | 4,625 | 18,865 (0%) | 0% | 0 | Common Stock | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2025 | 2,200 | 4,000 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 53.60 per share. | 10 Mar 2025 | 2,200 | 0 (0%) | 0% | 53.6 | 117,920 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.13 per share. | 10 Mar 2025 | 2,200 | 2,200 (0%) | 0% | 12.1 | 26,686 | Common Stock |
| Joseph K. Belanoff | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 350,000 | 350,000 | - | - | Stock option (right to buy) | |
| Joseph K. Belanoff | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 60.91 per share. | 28 Feb 2025 | 2,924 | 3,019,411 (2%) | 0% | 60.9 | 178,098 | Common Stock |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 60.58 per share. | 28 Feb 2025 | 250 | 22,906 (0%) | 0% | 60.6 | 15,145 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 140,000 | 140,000 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 292 | 23,490 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 59.07 per share. | 28 Feb 2025 | 292 | 23,198 (0%) | 0% | 59.1 | 17,248 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 232 | 13,034 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 140,000 | 140,000 | - | - | Stock option (right to buy) | |
| Atabak Mokari | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 60.58 per share. | 28 Feb 2025 | 228 | 12,570 (0%) | 0% | 60.6 | 13,812 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 59.07 per share. | 28 Feb 2025 | 232 | 12,802 (0%) | 0% | 59.1 | 13,704 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 59.07 per share. | 28 Feb 2025 | 266 | 85,356 (0%) | 0% | 59.1 | 15,713 | Common Stock |
| Sean Maduck | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 60.58 per share. | 28 Feb 2025 | 228 | 85,090 (0%) | 0% | 60.6 | 13,812 | Common Stock |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 60.69 per share. | 28 Feb 2025 | 18,303 | 85,622 (0%) | 0% | 60.7 | 1,110,818 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 18,303 | 123,683 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.05 per share. | 28 Feb 2025 | 18,303 | 103,925 (0%) | 0% | 5.0 | 92,430 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 140,000 | 140,000 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 266 | 85,622 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 60.58 per share. | 28 Feb 2025 | 182 | 8,577 (0%) | 0% | 60.6 | 11,026 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 216 | 9,009 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 59.07 per share. | 28 Feb 2025 | 216 | 8,793 (0%) | 0% | 59.1 | 12,759 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.56 per share. | 28 Feb 2025 | 4,579 | 13,588 (0%) | 0% | 13.6 | 62,091 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 60.69 per share. | 28 Feb 2025 | 4,579 | 9,009 (0%) | 0% | 60.7 | 277,902 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 140,000 | 140,000 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 4,579 | 91,992 | - | - | Stock option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 140,000 | 140,000 | - | - | Stock Option (right to buy) | |
| William Guyer | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2025 | 140,000 | 140,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 59.07 per share. | 28 Feb 2025 | 20,000 | 5,487 (0%) | 0% | 59.1 | 1,181,400 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.26 per share. | 28 Feb 2025 | 20,000 | 25,487 (0%) | 0% | 19.3 | 385,200 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 20,000 | 30,000 | - | - | Stock option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Feb 2025 | 150,000 | 0 | - | - | Stock Option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 68.11 per share. | 11 Feb 2025 | 85,176 | 183,405 (0%) | 0% | 68.1 | 5,801,337 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 11 Feb 2025 | 150,000 | 268,581 (0%) | 0% | 3.3 | 493,500 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.13 per share. | 10 Feb 2025 | 2,200 | 2,200 (0%) | 0% | 12.1 | 26,686 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2025 | 2,200 | 6,200 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 68.08 per share. | 10 Feb 2025 | 2,200 | 0 (0%) | 0% | 68.1 | 149,776 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Feb 2025 | 11,986 | 10,000 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 66.92 per share. | 03 Feb 2025 | 20,000 | 85,318 (0%) | 0% | 66.9 | 1,338,400 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.05 per share. | 03 Feb 2025 | 8,014 | 105,318 (0%) | 0% | 5.1 | 40,471 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.88 per share. | 03 Feb 2025 | 11,986 | 97,304 (0%) | 0% | 3.9 | 46,506 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Feb 2025 | 8,014 | 141,986 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Feb 2025 | 1,571 | 2,596 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 66.92 per share. | 03 Feb 2025 | 5,000 | 8,759 (0%) | 0% | 66.9 | 334,600 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 13.56 per share. | 03 Feb 2025 | 3,429 | 13,759 (0%) | 0% | 13.6 | 46,497 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 03 Feb 2025 | 1,571 | 10,330 (0%) | 0% | 11.4 | 17,831 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Feb 2025 | 3,429 | 96,571 | - | - | Stock option (right to buy) | |
| James N. Wilson | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Jan 2025 | 7,800 | 1,445,168 (1%) | 0% | 0 | Common Stock | |
| James N. Wilson | Director | Other type of transaction at price $ 0.00 per share. | 22 Jan 2025 | 146,742 | 1,452,968 (1%) | 0% | 0 | Common Stock | |
| James N. Wilson | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Jan 2025 | 146,742 | 0 (0%) | 0% | 0 | Common Stock | |
| James N. Wilson | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.03 per share. | 22 Jan 2025 | 103,258 | 146,742 (0%) | 0% | 59.0 | 6,095,320 | Common Stock |
| James N. Wilson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 22 Jan 2025 | 250,000 | 250,000 (0%) | 0% | 3.3 | 822,500 | Common Stock |
| James N. Wilson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Jan 2025 | 250,000 | 0 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.13 per share. | 10 Jan 2025 | 2,200 | 2,200 (0%) | 0% | 12.1 | 26,686 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Jan 2025 | 2,200 | 8,400 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 50.54 per share. | 10 Jan 2025 | 2,200 | 0 (0%) | 0% | 50.5 | 111,188 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 50.50 per share. | 02 Jan 2025 | 11,000 | 20,119 (0%) | 0% | 50.5 | 555,552 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2025 | 3,037 | 0 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2025 | 11,000 | 3,037 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 02 Jan 2025 | 3,037 | 23,156 (0%) | 0% | 3.3 | 9,992 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 02 Jan 2025 | 11,000 | 31,119 (0%) | 0% | 3.3 | 36,190 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2025 | 20,000 | 21,986 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.88 per share. | 02 Jan 2025 | 20,000 | 105,318 (0%) | 0% | 3.9 | 77,600 | Common Stock |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 50.39 per share. | 02 Jan 2025 | 20,000 | 85,318 (0%) | 0% | 50.4 | 1,007,800 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2025 | 5,000 | 4,167 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 50.39 per share. | 02 Jan 2025 | 5,000 | 8,759 (0%) | 0% | 50.4 | 251,950 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 02 Jan 2025 | 5,000 | 13,759 (0%) | 0% | 11.4 | 56,750 | Common Stock |
| Joseph K. Belanoff | Director, Chief Executive Officer | 31 Dec 2024 | 348,811 | 2,831,918 (2%) | 0% | 0 | Common Stock | ||
| Joseph K. Belanoff | Director, Chief Executive Officer | 31 Dec 2024 | 190,417 | 3,022,335 (2%) | 0% | 0 | Common Stock | ||
| Joseph K. Belanoff | Director, Chief Executive Officer | 31 Dec 2024 | 190,417 | 0 (0%) | 0% | 0 | Common Stock | ||
| Joseph K. Belanoff | Director, Chief Executive Officer | 31 Dec 2024 | 348,811 | 190,417 (0%) | 0% | 0 | Common Stock | ||
| James N. Wilson | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Dec 2024 | 7,800 | 1,306,226 (1%) | 0% | 0 | Common Stock | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Dec 2024 | 2,200 | 10,600 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 59.46 per share. | 10 Dec 2024 | 2,200 | 0 (0%) | 0% | 59.5 | 130,812 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.13 per share. | 10 Dec 2024 | 2,200 | 2,200 (0%) | 0% | 12.1 | 26,686 | Common Stock |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.68 per share. | 02 Dec 2024 | 324 | 19,539 (0%) | 0% | 57.7 | 18,688 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 59.21 per share. | 02 Dec 2024 | 290 | 19,829 (0%) | 0% | 59.2 | 17,171 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2024 | 290 | 20,119 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.68 per share. | 02 Dec 2024 | 182 | 12,336 (0%) | 0% | 57.7 | 10,498 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2024 | 231 | 12,798 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 59.21 per share. | 02 Dec 2024 | 231 | 12,567 (0%) | 0% | 59.2 | 13,678 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2024 | 265 | 85,318 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.68 per share. | 02 Dec 2024 | 295 | 84,788 (0%) | 0% | 57.7 | 17,016 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 59.21 per share. | 02 Dec 2024 | 265 | 85,053 (0%) | 0% | 59.2 | 15,691 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 59.21 per share. | 02 Dec 2024 | 215 | 8,544 (0%) | 0% | 59.2 | 12,730 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.68 per share. | 02 Dec 2024 | 165 | 8,329 (0%) | 0% | 57.7 | 9,517 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Dec 2024 | 215 | 8,759 (0%) | 0% | 0 | Common Stock | |
| William Guyer | Chief Development Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.68 per share. | 02 Dec 2024 | 309 | 5,487 (0%) | 0% | 57.7 | 17,823 | Common Stock |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Nov 2024 | 300 | 19,863 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 56.20 per share. | 22 Nov 2024 | 2,609 | 20,163 (0%) | 0% | 56.2 | 146,626 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 56.72 per share. | 22 Nov 2024 | 1,411 | 8,494 (0%) | 0% | 56.7 | 80,032 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.13 per share. | 11 Nov 2024 | 2,200 | 2,200 (0%) | 0% | 12.1 | 26,686 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Nov 2024 | 2,200 | 12,800 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 59.88 per share. | 11 Nov 2024 | 2,200 | 0 (0%) | 0% | 59.9 | 131,736 | Common Stock |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 48.97 per share. | 01 Nov 2024 | 6,606 | 5,796 (0%) | 0% | 49.0 | 323,496 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2024 | 6,606 | 453,394 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Nov 2024 | 3,394 | 450,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.65 per share. | 01 Nov 2024 | 3,394 | 9,190 (0%) | 0% | 21.6 | 73,480 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.65 per share. | 01 Nov 2024 | 6,606 | 12,402 (0%) | 0% | 21.7 | 143,020 | Common Stock |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 48.97 per share. | 01 Nov 2024 | 3,394 | 5,796 (0%) | 0% | 49.0 | 166,204 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.65 per share. | 01 Oct 2024 | 10,000 | 15,796 (0%) | 0% | 21.7 | 216,500 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Oct 2024 | 10,000 | 460,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 46.28 per share. | 01 Oct 2024 | 10,000 | 5,796 (0%) | 0% | 46.3 | 462,800 | Common Stock |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Sep 2024 | 415 | 9,665 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Sep 2024 | 11,000 | 14,037 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 27 Sep 2024 | 11,000 | 33,772 (0%) | 0% | 3.3 | 36,190 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 46.28 per share. | 27 Sep 2024 | 11,000 | 22,772 (0%) | 0% | 46.3 | 509,080 | Common Stock |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Sep 2024 | 415 | 9,665 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Sep 2024 | 300 | 23,642 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Other type of transaction at price $ 0.00 per share. | 17 Sep 2024 | 7,250 | 0 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Sep 2024 | 870 | 22,772 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Sep 2024 | 503 | 23,942 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 34.26 per share. | 03 Sep 2024 | 503 | 23,439 (0%) | 0% | 34.3 | 17,233 | Common Stock |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 35.30 per share. | 03 Sep 2024 | 254 | 22,936 (0%) | 0% | 35.3 | 8,966 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 35.30 per share. | 03 Sep 2024 | 143 | 11,718 (0%) | 0% | 35.3 | 5,048 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Sep 2024 | 400 | 12,518 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 34.26 per share. | 03 Sep 2024 | 400 | 12,118 (0%) | 0% | 34.3 | 13,704 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Sep 2024 | 458 | 85,083 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 34.26 per share. | 03 Sep 2024 | 458 | 84,625 (0%) | 0% | 34.3 | 15,691 | Common Stock |
| Sean Maduck | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 35.30 per share. | 03 Sep 2024 | 232 | 84,167 (0%) | 0% | 35.3 | 8,190 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 35.30 per share. | 03 Sep 2024 | 129 | 9,161 (0%) | 0% | 35.3 | 4,554 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Sep 2024 | 372 | 9,905 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 34.26 per share. | 03 Sep 2024 | 372 | 9,533 (0%) | 0% | 34.3 | 12,745 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.65 per share. | 03 Sep 2024 | 10,000 | 16,039 (0%) | 0% | 21.7 | 216,500 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Sep 2024 | 10,000 | 470,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 35.30 per share. | 03 Sep 2024 | 243 | 5,796 (0%) | 0% | 35.3 | 8,578 | Common Stock |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 35.30 per share. | 03 Sep 2024 | 10,000 | 6,039 (0%) | 0% | 35.3 | 353,000 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 35.71 per share. | 26 Aug 2024 | 3,101 | 23,190 (0%) | 0% | 35.7 | 110,737 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 01 Aug 2024 | 150 | 150 (0%) | 0% | 5.9 | 879 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 38.50 per share. | 01 Aug 2024 | 150 | 0 (0%) | 0% | 38.5 | 5,775 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Aug 2024 | 150 | 0 | - | - | Stock option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Aug 2024 | 60,000 | 0 | - | - | Stock Option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 37.94 per share. | 01 Aug 2024 | 34,773 | 118,581 (0%) | 0% | 37.9 | 1,319,288 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.81 per share. | 01 Aug 2024 | 60,000 | 153,354 (0%) | 0% | 2.8 | 168,600 | Common Stock |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 38.67 per share. | 01 Aug 2024 | 10,000 | 6,039 (0%) | 0% | 38.7 | 386,700 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.65 per share. | 01 Aug 2024 | 10,000 | 16,039 (0%) | 0% | 21.7 | 216,500 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Aug 2024 | 10,000 | 480,000 | - | - | Stock option (right to buy) | |
| Joseph K. Belanoff | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 31 Jul 2024 | 450,000 | 798,811 (0%) | 0% | 3.3 | 1,480,500 | Common Stock |
| Joseph K. Belanoff | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jul 2024 | 450,000 | 0 | - | - | Stock option (right to buy) | |
| Joseph K. Belanoff | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.67 per share. | 31 Jul 2024 | 259,583 | 539,228 (0%) | 0% | 38.7 | 10,038,075 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 01 Jul 2024 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2024 | 2,200 | 150 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 32.81 per share. | 01 Jul 2024 | 2,200 | 0 (0%) | 0% | 32.8 | 72,182 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 01 Jul 2024 | 11,000 | 37,291 (0%) | 0% | 3.3 | 36,190 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 32.49 per share. | 01 Jul 2024 | 11,000 | 26,291 (0%) | 0% | 32.5 | 357,390 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2024 | 11,000 | 25,037 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 32.49 per share. | 01 Jul 2024 | 5,000 | 9,290 (0%) | 0% | 32.5 | 162,452 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2024 | 5,000 | 9,167 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 01 Jul 2024 | 5,000 | 14,290 (0%) | 0% | 11.4 | 56,750 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jul 2024 | 10,000 | 490,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.65 per share. | 01 Jul 2024 | 10,000 | 16,039 (0%) | 0% | 21.7 | 216,500 | Common Stock |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 32.49 per share. | 01 Jul 2024 | 10,000 | 6,039 (0%) | 0% | 32.5 | 324,900 | Common Stock |
| G. Charles Robb | Chief Business Officer | Other type of transaction at price $ 0.00 per share. | 24 Jun 2024 | 1,000 | 6,700 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Jun 2024 | 550 | 7,250 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Jun 2024 | 550 | 9,250 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Jun 2024 | 550 | 9,250 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Jun 2024 | 2,650 | 26,291 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 04 Jun 2024 | 14,000 | 37,115 (0%) | 0% | 3.3 | 46,060 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2024 | 14,000 | 36,037 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 32.87 per share. | 04 Jun 2024 | 8,174 | 28,941 (0%) | 0% | 32.9 | 268,679 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 03 Jun 2024 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2024 | 2,200 | 2,350 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 30.21 per share. | 03 Jun 2024 | 2,200 | 0 (0%) | 0% | 30.2 | 66,462 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 1,818 | 23,115 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 31.30 per share. | 03 Jun 2024 | 1,818 | 21,297 (0%) | 0% | 31.3 | 56,903 | Common Stock |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.17 per share. | 03 Jun 2024 | 724 | 19,479 (0%) | 0% | 30.2 | 21,843 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.17 per share. | 03 Jun 2024 | 571 | 8,965 (0%) | 0% | 30.2 | 17,227 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 1,448 | 11,861 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 31.30 per share. | 03 Jun 2024 | 1,448 | 10,413 (0%) | 0% | 31.3 | 45,322 | Common Stock |
| Sean Maduck | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.17 per share. | 03 Jun 2024 | 823 | 84,399 (0%) | 0% | 30.2 | 24,830 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 03 Jun 2024 | 5,000 | 12,314 (0%) | 0% | 11.4 | 56,750 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 31.30 per share. | 03 Jun 2024 | 1,232 | 8,058 (0%) | 0% | 31.3 | 38,562 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.17 per share. | 03 Jun 2024 | 488 | 6,826 (0%) | 0% | 30.2 | 14,723 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 30.18 per share. | 03 Jun 2024 | 5,000 | 7,314 (0%) | 0% | 30.2 | 150,916 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2024 | 5,000 | 14,167 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 1,232 | 9,290 (0%) | 0% | 0 | Common Stock | |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jun 2024 | 10,000 | 50,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.26 per share. | 03 Jun 2024 | 10,000 | 16,039 (0%) | 0% | 19.3 | 192,600 | Common Stock |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 32.00 per share. | 03 Jun 2024 | 10,000 | 6,039 (0%) | 0% | 32 | 320,000 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 30.39 per share. | 28 May 2024 | 11,000 | 20,203 (0%) | 0% | 30.4 | 334,294 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 28 May 2024 | 11,000 | 31,203 (0%) | 0% | 3.3 | 36,190 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 May 2024 | 11,000 | 50,037 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 32.00 per share. | 28 May 2024 | 30,000 | 6,039 (0%) | 0% | 32 | 960,000 | Common Stock |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 May 2024 | 30,000 | 60,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.26 per share. | 28 May 2024 | 30,000 | 36,039 (0%) | 0% | 19.3 | 577,800 | Common Stock |
| James N. Wilson | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 23 May 2024 | 2,000 | 1,314,026 (1%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| George Leonard Baker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 30,000 | 30,000 | - | - | Stock Option (Right To Buy) | |
| Gregg H. Alton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| James N. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 80,000 | 80,000 | - | - | Employee stock option (right to buy) | |
| Kimberly Park | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| Gillian M. Cannon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| Joshua M. Murray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 May 2024 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2024 | 50,000 | 41,986 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.88 per share. | 13 May 2024 | 50,000 | 135,222 (0%) | 0% | 3.9 | 194,000 | Common Stock |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 28.00 per share. | 13 May 2024 | 50,000 | 85,222 (0%) | 0% | 28 | 1,400,000 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 09 May 2024 | 7,227 | 7,314 (0%) | 0% | 26 | 187,902 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 09 May 2024 | 7,227 | 14,541 (0%) | 0% | 11.3 | 82,026 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 May 2024 | 7,227 | 19,167 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 02 May 2024 | 10,830 | 7,314 (0%) | 0% | 26 | 281,580 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 May 2024 | 10,830 | 26,394 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 02 May 2024 | 10,830 | 18,144 (0%) | 0% | 11.4 | 122,921 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 23.09 per share. | 01 May 2024 | 2,200 | 0 (0%) | 0% | 23.1 | 50,798 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 May 2024 | 2,200 | 4,550 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 01 May 2024 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| David L. Mahoney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.74 per share. | 10 Apr 2024 | 30,000 | 30,000 (0%) | 0% | 1.7 | 52,200 | Common Stock |
| David L. Mahoney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Apr 2024 | 30,000 | 0 | - | - | Stock option (right to buy) | |
| David L. Mahoney | Director | Other type of transaction at price $ 0.00 per share. | 10 Apr 2024 | 27,806 | 1,212,614 (1%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Other type of transaction at price $ 0.00 per share. | 10 Apr 2024 | 27,806 | 27,806 (0%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.80 per share. | 10 Apr 2024 | 2,194 | 27,806 (0%) | 0% | 23.8 | 52,217 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 04 Apr 2024 | 5,443 | 12,757 (0%) | 0% | 11.3 | 61,778 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Apr 2024 | 5,443 | 37,224 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 04 Apr 2024 | 5,443 | 7,314 (0%) | 0% | 26.0 | 141,524 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 01 Apr 2024 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2024 | 2,200 | - | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 25.30 per share. | 01 Apr 2024 | 2,200 | 0 (0%) | 0% | 25.3 | 55,660 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2024 | 500 | 42,667 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | See Remarks | Sale of securities on an exchange or to another person at price $ 26.01 per share. | 01 Apr 2024 | 500 | 7,314 (0%) | 0% | 26.0 | 13,004 | Common Stock |
| Joseph Douglas Lyon | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 01 Apr 2024 | 500 | 7,814 (0%) | 0% | 11.4 | 5,675 | Common Stock |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 25.01 per share. | 27 Mar 2024 | 25,953 | 85,222 (0%) | 0% | 25.0 | 649,025 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Mar 2024 | 25,953 | 91,986 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.88 per share. | 27 Mar 2024 | 25,953 | 111,175 (0%) | 0% | 3.9 | 100,698 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Mar 2024 | 10,000 | 0 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 25.00 per share. | 18 Mar 2024 | 17,219 | 75,222 (0%) | 0% | 25 | 430,475 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.88 per share. | 18 Mar 2024 | 17,219 | 92,441 (0%) | 0% | 3.9 | 66,810 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Mar 2024 | 17,219 | 117,939 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.61 per share. | 18 Mar 2024 | 10,000 | 85,222 (0%) | 0% | 2.6 | 26,100 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 23.59 per share. | 01 Mar 2024 | 2,200 | 0 (0%) | 0% | 23.6 | 51,898 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 2,200 | 8,950 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 01 Mar 2024 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 24.06 per share. | 01 Mar 2024 | 697 | 19,506 (0%) | 0% | 24.1 | 16,770 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 697 | 20,203 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 01 Mar 2024 | 656 | 18,809 (0%) | 0% | 24.1 | 15,783 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 24.06 per share. | 01 Mar 2024 | 554 | 8,982 (0%) | 0% | 24.1 | 13,329 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 554 | 9,536 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 01 Mar 2024 | 517 | 8,428 (0%) | 0% | 24.1 | 12,439 | Common Stock |
| Sean Maduck | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 01 Mar 2024 | 505 | 73,950 (0%) | 0% | 24.1 | 12,150 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 636 | 75,222 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 24.06 per share. | 01 Mar 2024 | 636 | 74,586 (0%) | 0% | 24.1 | 15,302 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 01 Mar 2024 | 474 | 6,300 (0%) | 0% | 24.1 | 11,404 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 507 | 7,314 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 24.06 per share. | 01 Mar 2024 | 507 | 6,807 (0%) | 0% | 24.1 | 12,198 | Common Stock |
| William Guyer | Chief Development Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 01 Mar 2024 | 604 | 6,039 (0%) | 0% | 24.1 | 14,532 | Common Stock |
| Lyon Joseph Douglas | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2024 | 1,000 | 43,167 | - | - | Stock option (right to buy) | |
| Joseph Lyon Douglas | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 16 Feb 2024 | 1,000 | 7,774 (0%) | 0% | 11.4 | 11,350 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 16 Feb 2024 | 1,000 | 6,774 (0%) | 0% | 26 | 26,000 | Common Stock |
| Maduck Sean | See Remarks | Sale of securities on an exchange or to another person at price $ 25.97 per share. | 15 Feb 2024 | 27,068 | 74,455 (0%) | 0% | 26.0 | 702,905 | Common Stock |
| Maduck Sean | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 12,226 | 0 | - | - | Stock Option (right to buy) | |
| Maduck Sean | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 15 Feb 2024 | 4,760 | 79,215 (0%) | 0% | 3.3 | 15,660 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 14,842 | 135,158 | - | - | Stock Option (right to buy) | |
| Maduck Sean | See Remarks | Sale of securities on an exchange or to another person at price $ 25.00 per share. | 15 Feb 2024 | 4,760 | 74,455 (0%) | 0% | 25 | 119,000 | Common Stock |
| Maduck Sean | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,760 | 12,226 | - | - | Stock option (right to buy) | |
| Maduck Sean | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.88 per share. | 15 Feb 2024 | 14,842 | 101,523 (0%) | 0% | 3.9 | 57,587 | Common Stock |
| Maduck Sean | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 15 Feb 2024 | 12,226 | 86,681 (0%) | 0% | 3.3 | 40,224 | Common Stock |
| Douglas Joseph Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 150,000 | 150,000 | - | - | Stock option (right to buy) | |
| Guyer William | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Hunt Hazel | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Joseph K. Belanoff | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 500,000 | 500,000 | - | - | Stock option (right to buy) | |
| Robb Charles G. | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Maduck Sean | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2024 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| N. Swisher Daniel | Director | Sale of securities on an exchange or to another person at price $ 22.00 per share. | 01 Feb 2024 | 2,200 | 0 (0%) | 0% | 22 | 48,400 | Common Stock |
| Swisher N. Daniel | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2024 | 2,200 | 11,150 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 01 Feb 2024 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jan 2024 | 50,000 | 0 | - | - | Stock Option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.46 per share. | 08 Jan 2024 | 29,792 | 93,354 (0%) | 0% | 27.5 | 818,088 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.02 per share. | 08 Jan 2024 | 50,000 | 123,146 (0%) | 0% | 3.0 | 151,000 | Common Stock |
| N. Daniel Swisher | Director | Sale of securities on an exchange or to another person at price $ 22.11 per share. | 02 Jan 2024 | 2,200 | 0 (0%) | 0% | 22.1 | 48,642 | Common Stock |
| N. Swisher Daniel | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2024 | 2,200 | 13,350 | - | - | Stock option (right to buy) | |
| Swisher N. Daniel | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 02 Jan 2024 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| Charles Robb G. | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2023 | 1,175 | 19,465 (0%) | 0% | 0 | Common Stock | |
| Guyer William | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.26 per share. | 22 Dec 2023 | 10,000 | 16,643 (0%) | 0% | 19.3 | 192,600 | Common Stock |
| Guyer William | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2023 | 10,000 | 90,000 | - | - | Stock Option (right to buy) | |
| William Guyer | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 32.00 per share. | 22 Dec 2023 | 10,000 | 6,643 (0%) | 0% | 32 | 320,000 | Common Stock |
| G. Robb Charles | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 15 Dec 2023 | 750 | 20,640 (0%) | 0% | 0 | Common Stock | |
| Charles G. Robb | Chief Business Officer | Other type of transaction at price $ 0.00 per share. | 13 Dec 2023 | 1,000 | 7,700 (0%) | 0% | 0 | Common Stock | |
| Robb Charles G. | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Dec 2023 | 639 | 8,700 (0%) | 0% | 0 | Common Stock | |
| Robb Charles G. | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Dec 2023 | 639 | 8,700 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Dec 2023 | 639 | 8,700 (0%) | 0% | 0 | Common Stock | |
| Charles G. Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.26 per share. | 04 Dec 2023 | 8,788 | 28,983 (0%) | 0% | 26.3 | 230,773 | Common Stock |
| Charles G. Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Dec 2023 | 15,000 | 61,037 | - | - | Stock option (right to buy) | |
| Charles G. Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 27.01 per share. | 04 Dec 2023 | 6,212 | 21,390 (0%) | 0% | 27.0 | 167,786 | Common Stock |
| Robb G. Charles | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 04 Dec 2023 | 15,000 | 37,771 (0%) | 0% | 3.3 | 49,350 | Common Stock |
| Robb Charles G. | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 26.27 per share. | 04 Dec 2023 | 1,381 | 27,602 (0%) | 0% | 26.3 | 36,277 | Common Stock |
| William Guyer | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 25.97 per share. | 01 Dec 2023 | 609 | 6,034 (0%) | 0% | 26.0 | 15,816 | Common Stock |
| Douglas Joseph Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2023 | 460 | 6,774 (0%) | 0% | 0 | Common Stock | |
| Swisher N. Daniel | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 01 Dec 2023 | 2,200 | 2,200 (0%) | 0% | 5.9 | 12,892 | Common Stock |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 25.56 per share. | 01 Dec 2023 | 25,000 | 73,291 (0%) | 0% | 25.6 | 639,048 | Common Stock |
| Guyer William | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2023 | 609 | 6,643 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2023 | 508 | 8,945 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2023 | 582 | 74,455 (0%) | 0% | 0 | Common Stock | |
| N. Swisher Daniel | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2023 | 2,200 | 15,550 | - | - | Stock option (right to buy) | |
| Maduck Sean | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 01 Dec 2023 | 14,991 | 98,291 (0%) | 0% | 3.3 | 49,320 | Common Stock |
| Douglas Joseph Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 25.97 per share. | 01 Dec 2023 | 460 | 6,314 (0%) | 0% | 26.0 | 11,946 | Common Stock |
| Douglas Joseph Lyon | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 01 Dec 2023 | 2,432 | 5,854 (0%) | 0% | 26 | 63,232 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 25.47 per share. | 01 Dec 2023 | 2,200 | 0 (0%) | 0% | 25.5 | 56,034 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2023 | 10,009 | 10,000 | - | - | Stock option (right to buy) | |
| Maduck Sean | See Remarks | Grant, award, or other acquisition of securities at price $ 25.97 per share. | 01 Dec 2023 | 582 | 73,873 (0%) | 0% | 26.0 | 15,115 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 25.97 per share. | 01 Dec 2023 | 508 | 8,437 (0%) | 0% | 26.0 | 13,193 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.61 per share. | 01 Dec 2023 | 10,009 | 83,300 (0%) | 0% | 2.6 | 26,123 | Common Stock |
| Maduck Sean | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2023 | 14,991 | 16,986 | - | - | Stock option (right to buy) | |
| Charles G. Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 25.97 per share. | 01 Dec 2023 | 638 | 22,133 (0%) | 0% | 26.0 | 16,569 | Common Stock |
| Joseph Lyon Douglas | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2023 | 5,000 | 44,167 | - | - | Stock option (right to buy) | |
| Lyon Douglas Joseph | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 01 Dec 2023 | 2,568 | 8,422 (0%) | 0% | 11.4 | 29,147 | Common Stock |
| Douglas Joseph Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 01 Dec 2023 | 2,432 | 8,286 (0%) | 0% | 11.3 | 27,603 | Common Stock |
| G. Robb Charles | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2023 | 638 | 22,771 (0%) | 0% | 0 | Common Stock | |
| Lyon Douglas Joseph | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 01 Dec 2023 | 2,568 | 5,854 (0%) | 0% | 26 | 66,768 | Common Stock |
| David L. Mahoney | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Aug 2023 | 34,850 | 1,169,808 (1%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Aug 2023 | 17,420 | 1,204,658 (1%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Aug 2023 | 34,850 | 46,147 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.27 per share. | 21 Aug 2023 | 3,755 | 8,887 (0%) | 0% | 8.3 | 31,054 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Aug 2023 | 833 | 64,167 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Aug 2023 | 3,755 | 0 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 31.19 per share. | 21 Aug 2023 | 4,588 | 5,132 (0%) | 0% | 31.2 | 143,100 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 21 Aug 2023 | 833 | 9,720 (0%) | 0% | 11.4 | 9,455 | Common Stock |
| David L. Mahoney | Director | Sale of securities on an exchange or to another person at price $ 30.95 per share. | 14 Aug 2023 | 10,000 | 11,297 (0%) | 0% | 30.9 | 309,467 | Common Stock |
| David L. Mahoney | Director | Sale of securities on an exchange or to another person at price $ 30.95 per share. | 14 Aug 2023 | 15,000 | 1,222,078 (1%) | 0% | 30.9 | 464,201 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 30.89 per share. | 14 Aug 2023 | 20,455 | 73,146 (0%) | 0% | 30.9 | 631,753 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.48 per share. | 08 Aug 2023 | 29,545 | 93,601 (0%) | 0% | 30.5 | 900,532 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Aug 2023 | 50,000 | 0 | - | - | Stock option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.02 per share. | 08 Aug 2023 | 50,000 | 123,146 (0%) | 0% | 3.0 | 151,000 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.86 per share. | 07 Aug 2023 | 650 | 2,850 (0%) | 0% | 5.9 | 3,809 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 30.16 per share. | 07 Aug 2023 | 650 | 0 (0%) | 0% | 30.2 | 19,601 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 30.14 per share. | 07 Aug 2023 | 2,200 | 650 (0%) | 0% | 30.1 | 66,308 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.55 per share. | 07 Aug 2023 | 2,200 | 2,200 (0%) | 0% | 6.6 | 14,410 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Aug 2023 | 650 | 49,350 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Aug 2023 | 2,200 | 5,300 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Aug 2023 | 412 | 51,571 | - | - | Stock Option (Right to Buy) | |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.27 per share. | 07 Aug 2023 | 412 | 5,132 (0%) | 0% | 8.3 | 3,407 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 31.22 per share. | 07 Aug 2023 | 412 | 4,720 (0%) | 0% | 31.2 | 12,863 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jul 2023 | 10,000 | 0 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.92 per share. | 17 Jul 2023 | 10,000 | 72,698 (0%) | 0% | 1.9 | 19,200 | Common Stock |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 13 Jun 2023 | 600 | 20,029 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 725 | 23,454 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 725 | 22,729 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 725 | 22,004 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 725 | 21,279 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 650 | 20,629 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 725 | 8,061 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 725 | 8,061 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Jun 2023 | 725 | 8,061 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jun 2023 | 10,000 | 56,571 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | Chief Accounting Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.35 per share. | 06 Jun 2023 | 10,000 | 15,132 (0%) | 0% | 11.4 | 113,500 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Sale of securities on an exchange or to another person at price $ 23.60 per share. | 06 Jun 2023 | 10,000 | 5,132 (0%) | 0% | 23.6 | 236,000 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 22.97 per share. | 01 Jun 2023 | 2,091 | 22,088 (0%) | 0% | 23.0 | 48,030 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2023 | 2,091 | 24,179 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2023 | 1,651 | 7,408 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 22.97 per share. | 01 Jun 2023 | 1,651 | 5,757 (0%) | 0% | 23.0 | 37,923 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2023 | 1,658 | 62,698 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 22.97 per share. | 01 Jun 2023 | 1,658 | 61,040 (0%) | 0% | 23.0 | 38,084 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 22.97 per share. | 01 Jun 2023 | 1,411 | 3,721 (0%) | 0% | 23.0 | 32,411 | Common Stock |
| Joseph Douglas Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2023 | 1,411 | 5,132 (0%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| George Leonard Baker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 30,000 | 30,000 | - | - | Stock Option (Right To Buy) | |
| Gregg H. Alton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| James N. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 80,000 | 80,000 | - | - | Stock option (right to buy) | |
| Kimberly Park | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| Gillian M. Cannon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| Joshua M. Murray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2023 | 30,000 | 30,000 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 23.87 per share. | 09 May 2023 | 30,000 | 33,997 (0%) | 0% | 23.9 | 716,100 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 24.07 per share. | 09 May 2023 | 14,000 | 19,997 (0%) | 0% | 24.1 | 336,980 | Common Stock |
| David L. Mahoney | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.76 per share. | 08 May 2023 | 2,197 | 1,237,078 (1%) | 0% | 23.8 | 52,201 | Common Stock |
| David L. Mahoney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.74 per share. | 08 May 2023 | 30,000 | 1,239,275 (1%) | 0% | 1.7 | 52,200 | Common Stock |
| David L. Mahoney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2023 | 30,000 | 0 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 May 2023 | 60,000 | 38,963 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.92 per share. | 05 May 2023 | 45,000 | 64,583 (0%) | 0% | 1.9 | 86,400 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 05 May 2023 | 60,000 | 124,583 (0%) | 0% | 3.3 | 197,400 | Common Stock |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.07 per share. | 05 May 2023 | 60,586 | 63,997 (0%) | 0% | 24.1 | 1,458,305 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 May 2023 | 45,000 | 0 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 1,600 | 19,583 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 19.86 per share. | 01 Mar 2023 | 1,600 | 17,983 (0%) | 0% | 19.9 | 31,776 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 19.86 per share. | 01 Mar 2023 | 1,260 | 2,846 (0%) | 0% | 19.9 | 25,024 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 1,260 | 4,106 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 19.86 per share. | 01 Mar 2023 | 1,460 | 57,922 (0%) | 0% | 19.9 | 28,996 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 1,460 | 59,382 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 1,155 | 2,310 (0%) | 0% | 0 | Common Stock | |
| Joseph Douglas Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 19.86 per share. | 01 Mar 2023 | 1,155 | 1,155 (0%) | 0% | 19.9 | 22,938 | Common Stock |
| William Guyer | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 19.86 per share. | 01 Mar 2023 | 1,472 | 3,316 (0%) | 0% | 19.9 | 29,234 | Common Stock |
| William Guyer | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 1,472 | 4,788 (0%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 21,297 | 1,209,275 (1%) | 0% | 0 | Common Stock | |
| David L. Mahoney | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 26,030 | 1,230,572 (1%) | 0% | 0 | Common Stock | |
| George Leonard Baker | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 207 | 1,046,631 (0%) | 0% | 0 | Common Stock | |
| George Leonard Baker | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 207 | 955,262 (0%) | 0% | 0 | Common Stock | |
| James N. Wilson | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 12,000 | 1,319,026 (1%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 750 | 6,564 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 750 | 18,893 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 750 | 6,564 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 750 | 19,643 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 750 | 6,564 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 750 | 20,393 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 772 | 7,336 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 772 | 7,336 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 772 | 7,336 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 1,950 | 16,943 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 560 | 16,383 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 25.28 per share. | 01 Dec 2022 | 625 | 56,462 (0%) | 0% | 25.3 | 15,800 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2022 | 625 | 31,977 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 01 Dec 2022 | 625 | 57,087 (0%) | 0% | 3.3 | 2,056 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 26.03 per share. | 22 Nov 2022 | 186 | 21,143 (0%) | 0% | 26.0 | 4,842 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 26.03 per share. | 22 Nov 2022 | 4,814 | 21,329 (0%) | 0% | 26.0 | 125,308 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 26.06 per share. | 17 Nov 2022 | 10,000 | 39,544 (0%) | 0% | 26.1 | 260,600 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 26.43 per share. | 17 Nov 2022 | 13,401 | 26,143 (0%) | 0% | 26.4 | 354,188 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 10 Nov 2022 | 25,000 | 81,462 (0%) | 0% | 3.3 | 82,250 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Nov 2022 | 25,000 | 32,602 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 25.57 per share. | 10 Nov 2022 | 25,000 | 56,462 (0%) | 0% | 25.6 | 639,250 | Common Stock |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 25.64 per share. | 03 Oct 2022 | 25,000 | 56,462 (0%) | 0% | 25.6 | 641,000 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Oct 2022 | 25,000 | 57,602 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 03 Oct 2022 | 25,000 | 81,462 (0%) | 0% | 3.3 | 82,250 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.04 per share. | 28 Sep 2022 | 29,997 | 73,146 (0%) | 0% | 26.0 | 781,122 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Sep 2022 | 50,000 | 0 | - | - | Stock option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 28 Sep 2022 | 50,000 | 103,143 (0%) | 0% | 2.1 | 104,000 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 26.06 per share. | 07 Sep 2022 | 50,000 | 49,544 (0%) | 0% | 26.1 | 1,303,000 | Common Stock |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Sep 2022 | 1,010 | 99,544 (0%) | 0% | 0 | Common Stock | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 25.98 per share. | 01 Sep 2022 | 1,010 | 98,534 (0%) | 0% | 26.0 | 26,240 | Common Stock |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Sep 2022 | 793 | 1,586 (0%) | 0% | 0 | Common Stock | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 25.98 per share. | 01 Sep 2022 | 793 | 793 (0%) | 0% | 26.0 | 20,602 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Sep 2022 | 922 | 56,462 (0%) | 0% | 0 | Common Stock | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 25.98 per share. | 01 Sep 2022 | 922 | 55,540 (0%) | 0% | 26.0 | 23,954 | Common Stock |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 25.84 per share. | 01 Sep 2022 | 25,000 | 54,618 (0%) | 0% | 25.8 | 646,000 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 01 Sep 2022 | 25,000 | 79,618 (0%) | 0% | 3.3 | 82,250 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2022 | 25,000 | 82,602 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Sep 2022 | 922 | 1,844 (0%) | 0% | 0 | Common Stock | |
| William Guyer | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 25.98 per share. | 01 Sep 2022 | 922 | 922 (0%) | 0% | 26.0 | 23,954 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 30 Aug 2022 | 167,323 | 191,446 (0%) | 0% | 2.1 | 348,032 | Common Stock |
| G. Charles Robb | Chief Business Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.14 per share. | 30 Aug 2022 | 93,922 | 97,524 (0%) | 0% | 26.1 | 2,455,121 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Aug 2022 | 167,323 | 0 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.60 per share. | 19 Aug 2022 | 406 | 54,618 (0%) | 0% | 27.6 | 11,206 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 19 Aug 2022 | 15,000 | 55,024 (0%) | 0% | 2.2 | 33,600 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Aug 2022 | 15,000 | 0 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 28.70 per share. | 12 Aug 2022 | 24,800 | 40,024 (0%) | 0% | 28.7 | 711,760 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.92 per share. | 12 Aug 2022 | 9,800 | 49,824 (0%) | 0% | 1.9 | 18,816 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 12 Aug 2022 | 15,000 | 64,824 (0%) | 0% | 3.3 | 49,350 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2022 | 15,000 | 11,059 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2022 | 9,800 | 10,000 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 28.70 per share. | 09 Aug 2022 | 200 | 40,024 (0%) | 0% | 28.7 | 5,740 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2022 | 200 | 19,800 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.92 per share. | 09 Aug 2022 | 200 | 40,224 (0%) | 0% | 1.9 | 384 | Common Stock |
| Daniel N. Swisher | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 28.39 per share. | 08 Aug 2022 | 4,615 | 15,385 (0%) | 0% | 28.4 | 131,020 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Aug 2022 | 20,000 | 7,500 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 28.32 per share. | 08 Aug 2022 | 15,385 | 0 (0%) | 0% | 28.3 | 435,703 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 6.55 per share. | 08 Aug 2022 | 20,000 | 20,000 (0%) | 0% | 6.6 | 131,000 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.92 per share. | 18 Jul 2022 | 5,000 | 65,024 (0%) | 0% | 1.9 | 9,600 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jul 2022 | 5,000 | 20,000 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jul 2022 | 20,000 | 0 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Sale of securities on an exchange or to another person at price $ 27.37 per share. | 18 Jul 2022 | 25,000 | 40,024 (0%) | 0% | 27.4 | 684,250 | Common Stock |
| Sean Maduck | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 18 Jul 2022 | 20,000 | 60,024 (0%) | 0% | 2.1 | 41,600 | Common Stock |
| Joseph K. Belanoff | Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.21 per share. | 06 Jul 2022 | 451,189 | 348,811 (0%) | 0% | 26.2 | 11,825,664 | Common Stock |
| Joseph K. Belanoff | Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jul 2022 | 800,000 | 0 | - | - | Stock option (right to buy) | |
| Joseph K. Belanoff | Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 26.26 per share. | 06 Jul 2022 | 55,111 | 2,483,107 (2%) | 0% | 26.3 | 1,446,945 | Common Stock |
| Joseph K. Belanoff | Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 26.27 per share. | 06 Jul 2022 | 279,908 | 2,538,218 (2%) | 0% | 26.3 | 7,352,008 | Common Stock |
| Joseph K. Belanoff | Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 06 Jul 2022 | 800,000 | 800,000 (0%) | 0% | 2.1 | 1,664,000 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 06 Jul 2022 | 45,000 | 24,123 (0%) | 0% | 26 | 1,170,000 | Common Stock |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jul 2022 | 32,677 | 114,964 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 06 Jul 2022 | 32,677 | 69,123 (0%) | 0% | 2.1 | 67,968 | Common Stock |
| James N. Wilson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2022 | 300,000 | 0 | - | - | Stock option (right to buy) | |
| James N. Wilson | Director | Other type of transaction at price $ 0.00 per share. | 14 Jun 2022 | 168,181 | 1,331,026 (1%) | 0% | 0 | Common Stock | |
| James N. Wilson | Director | Other type of transaction at price $ 0.00 per share. | 14 Jun 2022 | 168,181 | 168,181 (0%) | 0% | 0 | Common Stock | |
| James N. Wilson | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.10 per share. | 14 Jun 2022 | 131,819 | 168,181 (0%) | 0% | 21.1 | 2,781,381 | Common Stock |
| James N. Wilson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 14 Jun 2022 | 300,000 | 300,000 (0%) | 0% | 2.1 | 624,000 | Common Stock |
| David L. Mahoney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| George Leonard Baker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 20,000 | 20,000 | - | - | Stock Option (Right To Buy) | |
| Gregg H. Alton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| James N. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 45,000 | 90,000 | - | - | Stock option (right to buy) | |
| James N. Wilson | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 May 2022 | 12,000 | 1,162,845 (1%) | 0% | 0 | Common Stock | |
| Kimberly Park | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| Gillian M. Cannon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| Joshua M. Murray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2022 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| David L. Mahoney | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.00 per share. | 27 May 2022 | 5,786 | 24,214 (0%) | 0% | 21 | 121,506 | Common Stock |
| David L. Mahoney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 May 2022 | 30,000 | 0 | - | - | Stock Option (Right to Buy) | |
| David L. Mahoney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.05 per share. | 27 May 2022 | 30,000 | 30,000 (0%) | 0% | 4.1 | 121,500 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 19.55 per share. | 17 May 2022 | 28,745 | 42,701 (0%) | 0% | 19.6 | 561,965 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 19.57 per share. | 17 May 2022 | 6,127 | 36,446 (0%) | 0% | 19.6 | 119,928 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 19.55 per share. | 17 May 2022 | 128 | 42,573 (0%) | 0% | 19.5 | 2,502 | Common Stock |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2022 | 50,000 | 50,000 | - | - | Stock Option (Right to Buy) | |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 24.67 per share. | 17 Mar 2022 | 4,988 | 71,446 (0%) | 0% | 24.7 | 123,054 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 24.68 per share. | 17 Mar 2022 | 7,512 | 76,434 (0%) | 0% | 24.7 | 185,374 | Common Stock |
| Joseph K. Belanoff | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2022 | 500,000 | 500,000 | - | - | Stock option (right to buy) | |
| G. Charles Robb | Chief Business Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2022 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Atabak Mokari | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2022 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Sean Maduck | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2022 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Joseph Douglas Lyon | Chief Accounting Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2022 | 120,000 | 120,000 | - | - | Stock option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2022 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| William Guyer | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2022 | 200,000 | 200,000 | - | - | Stock option (right to buy) | |
| Hazel Hunt | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.16 per share. | 26 Jan 2022 | 25,350 | 53,143 (0%) | 0% | 17.2 | 435,006 | Common Stock |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jan 2022 | 40,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Hazel Hunt | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.32 per share. | 26 Jan 2022 | 40,000 | 78,493 (0%) | 0% | 3.3 | 132,800 | Common Stock |
| Sean Maduck | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Oct 2021 | 24,363 | 123,239 | - | - | Stock Option (Right to Buy) | |
| Sean Maduck | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Oct 2021 | 637 | 122,602 | - | - | Stock Option (Right to Buy) | |
| Sean Maduck | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 01 Oct 2021 | 24,363 | 64,387 (0%) | 0% | 3.3 | 80,154 | Common Stock |
| Sean Maduck | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 01 Oct 2021 | 24,363 | 40,024 (0%) | 0% | 20.0 | 487,375 | Common Stock |
| Sean Maduck | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.29 per share. | 01 Oct 2021 | 637 | 40,661 (0%) | 0% | 3.3 | 2,096 | Common Stock |
| Sean Maduck | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 01 Oct 2021 | 637 | 40,024 (0%) | 0% | 20 | 12,740 | Common Stock |
| G. Charles Robb | Chief Business Officer | Sale of securities on an exchange or to another person at price $ 20.76 per share. | 13 Sep 2021 | 806 | 135,701 (0%) | 0% | 20.8 | 16,736 | Common Stock |