57,345 XNAS Volume
XNAS 25 Mar, 2025 2:00 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| David Dieter | EVP & General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2025 | 68,449 | 68,449 (0%) | 0% | 0 | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 14 Mar 2025 | 2,255 | 124,421 (0%) | 0% | 30.0 | 67,661 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 14 Mar 2025 | 977 | 164,269 (0%) | 0% | 30.0 | 29,313 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 11 Mar 2025 | 15,387 | 126,676 (0%) | 0% | 30.0 | 461,672 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.01 per share. | 11 Mar 2025 | 10,445 | 165,246 (0%) | 0% | 30.0 | 313,413 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 11 Mar 2025 | 15,387 | 126,676 (0%) | 0% | 30.0 | 461,672 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 06 Mar 2025 | 3,295 | 144,411 (0%) | 0% | 30.0 | 98,854 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 06 Mar 2025 | 2,348 | 142,063 (0%) | 0% | 30.0 | 70,446 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 06 Mar 2025 | 1,504 | 175,691 (0%) | 0% | 30.0 | 45,121 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 06 Mar 2025 | 1,949 | 177,195 (0%) | 0% | 30 | 58,470 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.03 per share. | 04 Mar 2025 | 40,000 | 194,204 (0%) | 0% | 24.0 | 961,200 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2025 | 40,000 | 0 | - | - | Stock Option (Right to Purchase) | |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 28.50 per share. | 04 Mar 2025 | 26,067 | 108,137 (0%) | 0% | 28.5 | 742,946 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 28.03 per share. | 04 Mar 2025 | 20,000 | 134,204 (0%) | 0% | 28.0 | 560,528 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 28.08 per share. | 04 Mar 2025 | 40,000 | 154,204 (0%) | 0% | 28.1 | 1,123,160 | Common Stock |
| Michael T. Heffernan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 4,820 | 50,328 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 25,149 | 154,204 (0%) | 0% | 30.5 | 767,547 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 40,965 | 160,149 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 29,030 | 189,179 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 9,826 | 179,353 (0%) | 0% | 30.5 | 299,890 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 21,670 | 147,706 (0%) | 0% | 30.5 | 661,368 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 7,953 | 169,376 (0%) | 0% | 30.5 | 242,726 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 26,411 | 177,329 (0%) | 0% | 0 | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 45,016 | 150,918 (0%) | 0% | 0 | Common Stock | |
| Thomas B. Smith | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 4,399 | 87,742 (0%) | 0% | 30.5 | 134,257 | Common Stock |
| Thomas B. Smith | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 33,762 | 88,326 (0%) | 0% | 0 | Common Stock | |
| Thomas B. Smith | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 5,313 | 93,639 (0%) | 0% | 0 | Common Stock | |
| Thomas B. Smith | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 1,498 | 92,141 (0%) | 0% | 30.5 | 45,719 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 22,317 | 179,144 (0%) | 0% | 30.5 | 681,115 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 51,768 | 182,613 (0%) | 0% | 0 | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2025 | 26,957 | 209,570 (0%) | 0% | 0 | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.52 per share. | 10 Feb 2025 | 8,109 | 201,461 (0%) | 0% | 30.5 | 247,487 | Common Stock |
| Nancy S. Lurker | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Feb 2025 | 12,726 | 12,726 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.34 per share. | 10 Jan 2025 | 27,500 | 146,684 (0%) | 0% | 21.3 | 586,850 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 32.87 per share. | 10 Jan 2025 | 21,400 | 125,284 (0%) | 0% | 32.9 | 703,407 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 33.64 per share. | 10 Jan 2025 | 6,100 | 119,184 (0%) | 0% | 33.6 | 205,220 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Jan 2025 | 27,500 | 0 | - | - | Stock Option (Right to Purchase) | |
| Vikram Karnani | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Nov 2024 | 130,344 | 130,344 | - | - | Stock Option (Right to Purchase) | |
| Vikram Karnani | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Nov 2024 | 105,972 | 105,972 (0%) | 0% | 0 | Common Stock | |
| Thomas B. Smith | EVP and Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 36.62 per share. | 13 Sep 2024 | 9,593 | 53,816 (0%) | 0% | 36.6 | 351,320 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 37.46 per share. | 05 Sep 2024 | 977 | 119,184 (0%) | 0% | 37.5 | 36,594 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 39.14 per share. | 05 Sep 2024 | 2,400 | 120,161 (0%) | 0% | 39.1 | 93,941 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 38.18 per share. | 05 Sep 2024 | 16,848 | 122,561 (0%) | 0% | 38.2 | 643,257 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 33.22 per share. | 03 Jun 2024 | 700 | 139,409 (0%) | 0% | 33.2 | 23,254 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 32.55 per share. | 03 Jun 2024 | 24,300 | 140,109 (0%) | 0% | 32.5 | 790,926 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 34.21 per share. | 28 May 2024 | 19,710 | 130,845 (0%) | 0% | 34.2 | 674,368 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 33.98 per share. | 23 May 2024 | 56,807 | 105,902 (0%) | 0% | 34.0 | 1,930,455 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.03 per share. | 23 May 2024 | 51,209 | 190,127 (0%) | 0% | 24.0 | 1,230,552 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 May 2024 | 51,209 | 23,791 | - | - | Stock Option (Right to Purchase) | |
| Scott Dreyer | EVP & Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 May 2024 | 23,791 | 0 | - | - | Stock Option (Right to Purchase) | |
| Scott Dreyer | EVP & Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 24.03 per share. | 23 May 2024 | 23,791 | 162,709 (0%) | 0% | 24.0 | 571,698 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 33.82 per share. | 23 May 2024 | 51,209 | 138,918 (0%) | 0% | 33.8 | 1,732,093 | Common Stock |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 7,693 | 75,656 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 7,693 | 52,468 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 7,693 | 45,508 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 7,693 | 54,843 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 7,693 | 52,468 (0%) | 0% | 0 | Common Stock | |
| Neil F. McFarlane | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 7,693 | 49,365 (0%) | 0% | 0 | Common Stock | |
| Rita Balice-Gordon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 7,693 | 46,488 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2024 | 28,985 | 0 | - | - | Stock Option (Right to Purchase) | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2024 | 7,693 | 52,468 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | Director | Sale of securities on an exchange or to another person at price $ 32.30 per share. | 14 May 2024 | 28,985 | 44,775 (0%) | 0% | 32.3 | 936,311 | Common Stock |
| Garen G. Bohlin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.73 per share. | 14 May 2024 | 28,985 | 73,760 (0%) | 0% | 5.7 | 166,084 | Common Stock |
| Thomas B. Smith | EVP and Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 36.76 per share. | 29 Feb 2024 | 995 | 63,409 (0%) | 0% | 36.8 | 36,580 | Common Stock |
| Dreyer Scott | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 36.38 per share. | 26 Feb 2024 | 9,336 | 139,582 (0%) | 0% | 36.4 | 339,601 | Common Stock |
| Dreyer Scott | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 37.15 per share. | 26 Feb 2024 | 664 | 138,918 (0%) | 0% | 37.2 | 24,670 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 19,545 | 159,063 (0%) | 0% | 33.7 | 658,667 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 10,610 | 164,409 (0%) | 0% | 33.7 | 357,557 | Common Stock |
| R. Kuhlmann Shirley | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 21,146 | 175,019 (0%) | 0% | 33.7 | 712,620 | Common Stock |
| Kuhlmann Shirley R. | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 43,400 | 162,918 (0%) | 0% | 0 | Common Stock | |
| Thomas Smith B. | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 1,300 | 64,404 (0%) | 0% | 33.7 | 43,810 | Common Stock |
| B. Thomas Smith | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 30,800 | 62,980 (0%) | 0% | 0 | Common Stock | |
| R. Kuhlmann Shirley | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 33,247 | 196,165 (0%) | 0% | 0 | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 81,422 | 444,867 (1%) | 0% | 33.7 | 2,743,921 | Common Stock |
| Tupper Colleen | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 16,868 | 160,008 (0%) | 0% | 33.7 | 568,452 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 119,000 | 394,000 (1%) | 0% | 0 | Common Stock | |
| Dreyer Scott | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 10,145 | 148,918 (0%) | 0% | 33.7 | 341,887 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 40,600 | 146,020 (0%) | 0% | 0 | Common Stock | |
| Thomas B. Smith | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 4,623 | 67,603 (0%) | 0% | 0 | Common Stock | |
| Dreyer Scott | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 32,286 | 178,608 (0%) | 0% | 0 | Common Stock | |
| Tupper Colleen | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 9,453 | 150,555 (0%) | 0% | 33.7 | 318,566 | Common Stock |
| Ciaffoni Joseph | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 179,734 | 573,734 (1%) | 0% | 0 | Common Stock | |
| Smith B. Thomas | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 1,899 | 65,704 (0%) | 0% | 33.7 | 63,996 | Common Stock |
| Dreyer Scott | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 35,000 | 146,322 (0%) | 0% | 0 | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 30,856 | 176,876 (0%) | 0% | 0 | Common Stock | |
| Ciaffoni Joseph | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.70 per share. | 12 Feb 2024 | 47,445 | 526,289 (1%) | 0% | 33.7 | 1,598,897 | Common Stock |
| Dreyer Scott | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 32.28 per share. | 16 Jan 2024 | 23,560 | 111,322 (0%) | 0% | 32.3 | 760,519 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Dec 2023 | 4,357 | 16,875 | - | - | Stock Option (Right to Purchase) | |
| Ciaffoni Joseph | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.34 per share. | 21 Dec 2023 | 4,357 | 279,357 (0%) | 0% | 21.3 | 92,978 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.38 per share. | 21 Dec 2023 | 4,357 | 275,000 (0%) | 0% | 30.4 | 132,377 | Common Stock |
| Ciaffoni Joseph | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 14,516 | 47,686 | - | - | Stock Option (Right to Purchase) | |
| Ciaffoni Joseph | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.03 per share. | 18 Dec 2023 | 14,516 | 275,000 (0%) | 0% | 30.0 | 435,942 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 26,454 | 21,232 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.34 per share. | 18 Dec 2023 | 14,516 | 289,516 (0%) | 0% | 21.3 | 309,771 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.34 per share. | 18 Dec 2023 | 26,454 | 301,454 (0%) | 0% | 21.3 | 564,528 | Common Stock |
| Ciaffoni Joseph | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.34 per share. | 18 Dec 2023 | 27,798 | 302,798 (0%) | 0% | 21.3 | 593,209 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.40 per share. | 18 Dec 2023 | 26,454 | 275,000 (0%) | 0% | 30.4 | 804,210 | Common Stock |
| Ciaffoni Joseph | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2023 | 27,798 | 62,202 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.04 per share. | 18 Dec 2023 | 27,798 | 275,000 (0%) | 0% | 30.0 | 834,935 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 22.53 per share. | 26 Jun 2023 | 1,363 | 119,518 (0%) | 0% | 22.5 | 30,715 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 21.65 per share. | 26 Jun 2023 | 16,621 | 120,881 (0%) | 0% | 21.7 | 359,918 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.58 per share. | 01 Jun 2023 | 30,272 | 276,000 (0%) | 0% | 21.6 | 653,173 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.25 per share. | 01 Jun 2023 | 1,000 | 275,000 (0%) | 0% | 22.3 | 22,251 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.09 per share. | 01 Jun 2023 | 31,272 | 306,272 (0%) | 0% | 22.1 | 690,758 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.87 per share. | 30 May 2023 | 31,272 | 337,544 (0%) | 0% | 21.9 | 683,797 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.90 per share. | 30 May 2023 | 31,271 | 368,816 (1%) | 0% | 21.9 | 684,907 | Common Stock |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 67,963 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 44,775 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 44,775 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 37,815 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 47,150 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 44,775 (0%) | 0% | 0 | Common Stock | |
| Neil F. McFarlane | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 41,672 (0%) | 0% | 0 | Common Stock | |
| Rita Balice-Gordon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 9,792 | 38,795 (0%) | 0% | 0 | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 23.77 per share. | 15 Mar 2023 | 31,640 | 105,420 (0%) | 0% | 23.8 | 752,165 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 26.70 per share. | 01 Mar 2023 | 13,324 | 134,882 (0%) | 0% | 26.7 | 355,751 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 44,121 | 459,823 (1%) | 0% | 26.8 | 1,180,237 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 137,694 | 503,944 (1%) | 0% | - | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Feb 2023 | 11,250 | 0 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 117,500 | 366,250 (1%) | 0% | 0 | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 26.88 per share. | 10 Feb 2023 | 11,250 | 400,087 (1%) | 0% | 26.9 | 302,400 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.90 per share. | 10 Feb 2023 | 11,250 | 411,337 (1%) | 0% | 15.9 | 178,875 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 59,736 | 400,087 (1%) | 0% | 26.8 | 1,597,938 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 16,291 | 167,068 (0%) | 0% | 26.7 | 435,784 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 48,125 | 157,620 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 25,739 | 183,359 (0%) | 0% | - | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 7,755 | 159,313 (0%) | 0% | 26.7 | 207,446 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 26.88 per share. | 10 Feb 2023 | 21,811 | 137,502 (0%) | 0% | 26.9 | 586,280 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 44,275 | 147,073 (0%) | 0% | 0 | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 6,797 | 148,206 (0%) | 0% | 26.8 | 181,820 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 14,529 | 155,003 (0%) | 0% | 26.8 | 388,651 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 22,459 | 169,532 (0%) | 0% | - | Common Stock | |
| Thomas B. Smith | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 31,185 | 31,185 (0%) | 0% | 0 | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 12,565 | 147,914 (0%) | 0% | - | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 3,887 | 137,060 (0%) | 0% | 26.7 | 103,977 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.75 per share. | 10 Feb 2023 | 6,967 | 140,947 (0%) | 0% | 26.7 | 186,367 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 45,045 | 135,349 (0%) | 0% | 0 | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 27.83 per share. | 09 Jan 2023 | 7,341 | 102,867 (0%) | 0% | 27.8 | 204,300 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 28.58 per share. | 09 Jan 2023 | 69 | 102,798 (0%) | 0% | 28.6 | 1,972 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 27.08 per share. | 09 Jan 2023 | 10,424 | 110,208 (0%) | 0% | 27.1 | 282,282 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.00 per share. | 22 Dec 2022 | 147 | 250,954 (0%) | 0% | 23 | 3,381 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.00 per share. | 22 Dec 2022 | 110 | 251,101 (0%) | 0% | 23 | 2,530 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 24.19 per share. | 22 Dec 2022 | 400 | 248,750 (0%) | 0% | 24.2 | 9,676 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.65 per share. | 22 Dec 2022 | 1,804 | 249,150 (0%) | 0% | 23.7 | 42,665 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2022 | 15,995 | 3,820 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2022 | 4,989 | 19,815 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2022 | 237 | 24,804 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 23.00 per share. | 22 Dec 2022 | 237 | 28,023 (0%) | 0% | 23 | 5,451 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 22 Dec 2022 | 237 | 28,260 (0%) | 0% | 16.2 | 3,828 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2022 | 3,820 | 0 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 24.16 per share. | 22 Dec 2022 | 3,820 | 28,023 (0%) | 0% | 24.2 | 92,291 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 22 Dec 2022 | 3,820 | 31,843 (0%) | 0% | 16.2 | 61,693 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 23.63 per share. | 22 Dec 2022 | 15,995 | 28,023 (0%) | 0% | 23.6 | 377,962 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 22 Dec 2022 | 15,995 | 44,018 (0%) | 0% | 16.1 | 258,319 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 23.00 per share. | 22 Dec 2022 | 4,989 | 28,023 (0%) | 0% | 23 | 114,747 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 22 Dec 2022 | 4,989 | 33,012 (0%) | 0% | 16.1 | 80,572 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.11 per share. | 19 Dec 2022 | 7,333 | 251,211 (0%) | 0% | 23.1 | 169,466 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.07 per share. | 19 Dec 2022 | 9,375 | 258,544 (0%) | 0% | 23.1 | 216,281 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.01 per share. | 19 Dec 2022 | 1,134 | 267,919 (0%) | 0% | 23.0 | 26,093 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 19 Dec 2022 | 33,758 | 61,781 (0%) | 0% | 16.2 | 545,192 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2022 | 46,600 | 25,041 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2022 | 33,758 | 71,641 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2022 | 3,606 | 105,399 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 23.11 per share. | 19 Dec 2022 | 46,600 | 28,023 (0%) | 0% | 23.1 | 1,076,926 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 19 Dec 2022 | 46,600 | 74,623 (0%) | 0% | 16.2 | 752,590 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 23.08 per share. | 19 Dec 2022 | 33,758 | 28,023 (0%) | 0% | 23.1 | 779,135 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 23.04 per share. | 19 Dec 2022 | 3,606 | 28,023 (0%) | 0% | 23.0 | 83,082 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.15 per share. | 19 Dec 2022 | 3,606 | 31,629 (0%) | 0% | 16.2 | 58,237 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.90 per share. | 12 Dec 2022 | 10,669 | 38,692 (0%) | 0% | 14.9 | 158,968 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2022 | 7,904 | 0 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2022 | 94,259 | 0 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2022 | 59,524 | 0 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2022 | 1,510 | 0 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2022 | 15,741 | 0 | - | - | Stock Option (Right to Purchase)t to | |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2022 | 10,669 | 0 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 22.16 per share. | 12 Dec 2022 | 161,687 | 28,023 (0%) | 0% | 22.2 | 3,582,984 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.57 per share. | 12 Dec 2022 | 7,904 | 189,710 (0%) | 0% | 14.6 | 115,161 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.27 per share. | 12 Dec 2022 | 94,259 | 181,806 (0%) | 0% | 15.3 | 1,439,335 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.90 per share. | 12 Dec 2022 | 59,524 | 87,547 (0%) | 0% | 14.9 | 886,908 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 22.01 per share. | 12 Dec 2022 | 27,920 | 28,023 (0%) | 0% | 22.0 | 614,519 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.57 per share. | 12 Dec 2022 | 1,510 | 55,943 (0%) | 0% | 14.6 | 22,001 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.27 per share. | 12 Dec 2022 | 15,741 | 54,433 (0%) | 0% | 15.3 | 240,365 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.47 per share. | 01 Dec 2022 | 76,653 | 323,453 (0%) | 0% | 22.5 | 1,722,393 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Dec 2022 | 76,653 | 0 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.07 per share. | 01 Dec 2022 | 54,400 | 269,053 (0%) | 0% | 23.1 | 1,255,008 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.90 per share. | 01 Dec 2022 | 76,653 | 400,106 (1%) | 0% | 15.9 | 1,218,783 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.00 per share. | 28 Nov 2022 | 43 | 323,453 (0%) | 0% | 22 | 946 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.91 per share. | 28 Nov 2022 | 43 | 323,496 (0%) | 0% | 15.9 | 684 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Nov 2022 | 43 | 0 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.91 per share. | 22 Nov 2022 | 65 | 323,518 (0%) | 0% | 15.9 | 1,034 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Nov 2022 | 65 | 0 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.00 per share. | 22 Nov 2022 | 65 | 323,453 (0%) | 0% | 22 | 1,430 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Nov 2022 | 1,989 | 0 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.02 per share. | 18 Nov 2022 | 1,989 | 323,453 (0%) | 0% | 22.0 | 43,798 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.90 per share. | 18 Nov 2022 | 1,989 | 325,442 (0%) | 0% | 15.9 | 31,625 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 17.35 per share. | 04 Oct 2022 | 4,350 | 90,304 (0%) | 0% | 17.4 | 75,473 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 18.07 per share. | 15 Sep 2022 | 38,589 | 109,495 (0%) | 0% | 18.1 | 697,303 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 20.01 per share. | 11 Aug 2022 | 300 | 148,084 (0%) | 0% | 20.0 | 6,003 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.48 per share. | 11 Jul 2022 | 594 | 120,632 (0%) | 0% | 17.5 | 10,383 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.16 per share. | 01 Jul 2022 | 1,394 | 323,453 (0%) | 0% | 18.2 | 25,315 | Common Stock |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 14,035 | 58,171 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 14,035 | 34,983 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 14,035 | 34,983 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 14,035 | 28,023 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 14,035 | 37,358 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 14,035 | 34,983 (0%) | 0% | 0 | Common Stock | |
| Rita Balice-Gordon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 14,035 | 29,003 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.99 per share. | 16 Mar 2022 | 734 | 148,384 (0%) | 0% | 19.0 | 13,939 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 18.37 per share. | 01 Mar 2022 | 65,083 | 335,858 (0%) | 0% | 18.4 | 1,195,575 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 19.04 per share. | 01 Mar 2022 | 11,011 | 324,847 (0%) | 0% | 19.0 | 209,649 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 21.61 per share. | 18 Feb 2022 | 10,559 | 121,226 (0%) | 0% | 21.6 | 228,180 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 125,000 | 388,904 (1%) | 0% | 0 | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 65,034 | 453,938 (1%) | 0% | - | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 24,154 | 429,784 (1%) | 0% | 17.6 | 425,835 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 28,843 | 400,941 (1%) | 0% | 17.6 | 508,502 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 56,700 | 145,956 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 4,212 | 149,118 (0%) | 0% | 17.6 | 74,258 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 6,967 | 153,330 (0%) | 0% | 17.6 | 122,828 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 14,341 | 160,297 (0%) | 0% | - | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 4,016 | 131,785 (0%) | 0% | 17.6 | 70,802 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 13,675 | 142,444 (0%) | 0% | - | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 52,500 | 128,769 (0%) | 0% | 0 | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 6,643 | 135,801 (0%) | 0% | 17.6 | 117,116 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 6,256 | 136,564 (0%) | 0% | - | Common Stock | |
| Richard Malamut | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 1,838 | 130,264 (0%) | 0% | 17.6 | 32,404 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 4,462 | 132,102 (0%) | 0% | 17.6 | 78,665 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 36,750 | 130,308 (0%) | 0% | 0 | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 1,237 | 94,654 (0%) | 0% | 17.6 | 21,808 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 4,212 | 98,712 (0%) | 0% | - | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2022 | 52,500 | 94,500 (0%) | 0% | 0 | Common Stock | |
| Colleen Tupper | EVP & Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.63 per share. | 10 Feb 2022 | 2,821 | 95,891 (0%) | 0% | 17.6 | 49,734 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.05 per share. | 10 Jan 2022 | 701 | 76,269 (0%) | 0% | 19.0 | 13,354 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.68 per share. | 03 Jan 2022 | 1,090 | 263,904 (0%) | 0% | 18.7 | 20,361 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.67 per share. | 16 Sep 2021 | 734 | 89,256 (0%) | 0% | 19.7 | 14,438 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.03 per share. | 10 Aug 2021 | 1,386 | 264,994 (0%) | 0% | 19.0 | 26,376 | Common Stock |
| Alison B. Fleming | EVP & Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.03 per share. | 10 Aug 2021 | 1,386 | 143,694 (0%) | 0% | 19.0 | 26,376 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.17 per share. | 12 Jul 2021 | 595 | 82,663 (0%) | 0% | 23.2 | 13,786 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.99 per share. | 01 Jul 2021 | 1,394 | 266,380 (0%) | 0% | 24.0 | 33,442 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.90 per share. | 01 Jun 2021 | 4,672 | 273,635 (0%) | 0% | 22.9 | 106,989 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 01 Jun 2021 | 16,205 | 289,840 (0%) | 0% | 8.2 | 133,205 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 16,205 | 0 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.81 per share. | 01 Jun 2021 | 5,861 | 267,774 (0%) | 0% | 22.8 | 133,689 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.33 per share. | 01 Jun 2021 | 10,829 | 273,635 (0%) | 0% | 23.3 | 252,641 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.93 per share. | 01 Jun 2021 | 5,376 | 284,464 (0%) | 0% | 22.9 | 123,272 | Common Stock |
| Colleen Tupper | EVP & Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2021 | 42,000 | 42,000 (0%) | 0% | 0 | Common Stock | |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 9,941 | 44,136 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 9,941 | 20,948 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 9,941 | 20,948 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 9,941 | 13,988 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 9,941 | 23,323 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 9,941 | 20,948 (0%) | 0% | 0 | Common Stock | |
| Rita Balice-Gordon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 9,941 | 14,968 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 22.77 per share. | 10 May 2021 | 7,000 | 89,990 (0%) | 0% | 22.8 | 159,390 | Common Stock |
| Alison B. Fleming | EVP & Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.38 per share. | 01 Apr 2021 | 7,900 | 145,080 (0%) | 0% | 23.4 | 184,702 | Common Stock |
| Alison B. Fleming | EVP & Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.38 per share. | 01 Apr 2021 | 1,757 | 152,980 (0%) | 0% | 23.4 | 41,079 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.38 per share. | 01 Apr 2021 | 3,119 | 93,558 (0%) | 0% | 23.4 | 72,922 | Common Stock |
| Alison B. Fleming | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Mar 2021 | 5,984 | 154,737 (0%) | 0% | - | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.69 per share. | 16 Mar 2021 | 734 | 96,990 (0%) | 0% | 24.7 | 18,122 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 25.88 per share. | 15 Mar 2021 | 3,031 | 4,047 (0%) | 0% | 25.9 | 78,442 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 25.26 per share. | 15 Mar 2021 | 47,044 | 7,078 (0%) | 0% | 25.3 | 1,188,331 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.30 per share. | 01 Mar 2021 | 9,809 | 278,307 (0%) | 0% | 23.3 | 228,550 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 01 Mar 2021 | 48,616 | 343,075 (1%) | 0% | 8.2 | 399,624 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.56 per share. | 01 Mar 2021 | 54,959 | 288,116 (0%) | 0% | 22.6 | 1,239,875 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2021 | 48,616 | 16,205 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 8,498 | 309,747 (0%) | 0% | 25.9 | 220,523 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 15,288 | 294,459 (0%) | 0% | 26.0 | 396,724 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 2,564 | 221,355 (0%) | 0% | 26.0 | 66,536 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 5,927 | 215,428 (0%) | 0% | 26.0 | 153,806 | Common Stock |
| Alison B. Fleming | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 2,099 | 161,209 (0%) | 0% | 25.9 | 54,469 | Common Stock |
| Alison B. Fleming | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 5,045 | 156,164 (0%) | 0% | 26.0 | 130,918 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 2,163 | 101,419 (0%) | 0% | 26.0 | 56,130 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 3,695 | 97,724 (0%) | 0% | 25.9 | 95,885 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 24.89 per share. | 10 Feb 2021 | 2,100 | 89,056 (0%) | 0% | 24.9 | 52,269 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 3,283 | 91,156 (0%) | 0% | 26.0 | 85,194 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 1,901 | 94,439 (0%) | 0% | 26.0 | 49,331 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 25.33 per share. | 10 Feb 2021 | 5,798 | 83,258 (0%) | 0% | 25.3 | 146,863 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 1,542 | 96,677 (0%) | 0% | 26.0 | 40,015 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.95 per share. | 10 Feb 2021 | 758 | 98,219 (0%) | 0% | 25.9 | 19,670 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 28,989 | 318,245 (0%) | 0% | - | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 105,000 | 289,256 (0%) | 0% | 0 | Common Stock | |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 8,161 | 223,919 (0%) | 0% | - | Common Stock | |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 42,000 | 215,758 (0%) | 0% | 0 | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 6,529 | 163,308 (0%) | 0% | - | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 45,360 | 156,779 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 6,772 | 109,663 (0%) | 0% | - | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 24.45 per share. | 19 Jan 2021 | 6,081 | 103,582 (0%) | 0% | 24.4 | 148,680 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 45,360 | 102,891 (0%) | 0% | 0 | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 45,780 | 90,175 (0%) | 0% | 0 | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 6,165 | 96,340 (0%) | 0% | - | Common Stock | |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 36,960 | 96,790 (0%) | 0% | 0 | Common Stock | |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2021 | 2,187 | 98,977 (0%) | 0% | - | Common Stock | |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 22.89 per share. | 15 Jan 2021 | 1,322 | 44,395 (0%) | 0% | 22.9 | 30,261 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.18 per share. | 11 Jan 2021 | 701 | 45,717 (0%) | 0% | 21.2 | 14,847 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.03 per share. | 04 Jan 2021 | 1,090 | 184,256 (0%) | 0% | 20.0 | 21,833 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.49 per share. | 30 Nov 2020 | 4,672 | 185,346 (0%) | 0% | 18.5 | 86,385 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Nov 2020 | 16,000 | 19,378 | - | - | Stock Option (Right to Purchase) | |
| Alison B. Fleming | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.73 per share. | 18 Nov 2020 | 16,000 | 117,386 (0%) | 0% | 5.7 | 91,680 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Sale of securities on an exchange or to another person at price $ 20.82 per share. | 15 Oct 2020 | 7,060 | 57,531 (0%) | 0% | 20.8 | 146,989 | Common Stock |
| Rita Balice-Gordon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Sep 2020 | 10,055 | 10,055 | - | - | Stock Option (Right to Purchase) | |
| Rita Balice-Gordon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Sep 2020 | 5,027 | 5,027 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.33 per share. | 16 Sep 2020 | 734 | 64,591 (0%) | 0% | 19.3 | 14,188 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 19.13 per share. | 11 Aug 2020 | 13,071 | 54,122 (0%) | 0% | 19.1 | 250,048 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.89 per share. | 10 Aug 2020 | 1,386 | 190,018 (0%) | 0% | 18.9 | 26,182 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.89 per share. | 10 Aug 2020 | 1,515 | 173,758 (0%) | 0% | 18.9 | 28,618 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.89 per share. | 10 Aug 2020 | 1,515 | 101,386 (0%) | 0% | 18.9 | 28,618 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.73 per share. | 10 Jul 2020 | 594 | 47,847 (0%) | 0% | 16.7 | 9,938 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 17.01 per share. | 10 Jul 2020 | 1,429 | 46,418 (0%) | 0% | 17.0 | 24,307 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.37 per share. | 01 Jul 2020 | 1,394 | 191,404 (0%) | 0% | 17.4 | 24,214 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 01 Jun 2020 | 64,820 | 269,335 (0%) | 0% | 8.2 | 532,820 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2020 | 64,820 | 64,821 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.30 per share. | 01 Jun 2020 | 100 | 192,798 (0%) | 0% | 21.3 | 2,130 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.47 per share. | 01 Jun 2020 | 5,761 | 192,898 (0%) | 0% | 20.5 | 117,928 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 22.08 per share. | 01 Jun 2020 | 100 | 198,659 (0%) | 0% | 22.1 | 2,208 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.53 per share. | 01 Jun 2020 | 70,576 | 198,759 (0%) | 0% | 21.5 | 1,519,501 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.24 per share. | 01 Jun 2020 | 4,672 | 204,515 (0%) | 0% | 21.2 | 99,233 | Common Stock |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 34,195 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 11,007 (0%) | 0% | 0 | Common Stock | |
| Theodore R. Schroeder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 11,007 (0%) | 0% | 0 | Common Stock | |
| Theodore R. Schroeder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 11,007 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.05 per share. | 20 May 2020 | 18,650 | 63,146 (0%) | 0% | 22.1 | 411,233 | Common Stock |
| Michael T. Heffernan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 67,193 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 13,382 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 11,007 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| David Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 4,047 | 21,164 (0%) | 0% | 0 | Common Stock | |
| David Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2020 | 8,095 | 8,095 | - | - | Stock Option (Right to Purchase) | |
| Scott Dreyer | EVP & Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.90 per share. | 18 May 2020 | 8,000 | 56,441 (0%) | 0% | 15.9 | 127,200 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 24.00 per share. | 18 May 2020 | 8,000 | 48,441 (0%) | 0% | 24 | 192,000 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 May 2020 | 8,000 | 17,600 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 22.64 per share. | 13 May 2020 | 5,905 | 81,796 (0%) | 0% | 22.6 | 133,689 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 21.21 per share. | 13 May 2020 | 11,969 | 87,701 (0%) | 0% | 21.2 | 253,862 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 20.92 per share. | 13 May 2020 | 1,380 | 99,670 (0%) | 0% | 20.9 | 28,870 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 21.12 per share. | 13 May 2020 | 5,261 | 105,629 (0%) | 0% | 21.1 | 111,112 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 22.74 per share. | 13 May 2020 | 2,728 | 102,901 (0%) | 0% | 22.7 | 62,035 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 22.61 per share. | 13 May 2020 | 4,434 | 48,441 (0%) | 0% | 22.6 | 100,253 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.49 per share. | 01 Apr 2020 | 2,920 | 59,830 (0%) | 0% | 15.5 | 45,231 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.41 per share. | 16 Mar 2020 | 734 | 65,325 (0%) | 0% | 15.4 | 11,311 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.62 per share. | 10 Feb 2020 | 7,499 | 209,187 (0%) | 0% | 21.6 | 162,128 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.62 per share. | 10 Feb 2020 | 4,025 | 175,273 (0%) | 0% | 21.6 | 87,021 | Common Stock |
| Michael T. Heffernan | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.62 per share. | 10 Feb 2020 | 4,962 | 101,050 (0%) | 0% | 21.6 | 107,278 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.62 per share. | 10 Feb 2020 | 3,568 | 110,890 (0%) | 0% | 21.6 | 77,140 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.62 per share. | 10 Feb 2020 | 2,085 | 66,059 (0%) | 0% | 21.6 | 45,078 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.62 per share. | 10 Feb 2020 | 1,966 | 52,875 (0%) | 0% | 21.6 | 42,505 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 45,000 | 216,686 (0%) | 0% | 0 | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 90,000 | 90,000 | - | - | Stock Option (Right to Purchase) | |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 31,250 | 31,250 | - | - | Stock Option (Right to Purchase) | |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 28,125 | 179,298 (0%) | 0% | 0 | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 18,616 | 114,458 (0%) | 0% | 0 | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 22,500 | 95,842 (0%) | 0% | 0 | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 25,000 | 25,000 | - | - | Stock Option (Right to Purchase) | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 24,750 | 68,144 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 27,500 | 27,500 | - | - | Stock Option (Right to Purchase) | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 21,250 | 21,250 | - | - | Stock Option (Right to Purchase) | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 19,125 | 54,841 (0%) | 0% | 0 | Common Stock | |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 20,250 | 62,750 (0%) | 0% | 0 | Common Stock | |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2020 | 22,500 | 22,500 | - | - | Stock Option (Right to Purchase) | |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.56 per share. | 21 Jan 2020 | 214 | 151,173 (0%) | 0% | 21.6 | 4,614 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Jan 2020 | 275,463 | 0 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.56 per share. | 21 Jan 2020 | 787 | 106,012 (0%) | 0% | 21.6 | 16,968 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 22.69 per share. | 21 Jan 2020 | 32,700 | 106,799 (0%) | 0% | 22.7 | 741,963 | Common Stock |
| Michael T. Heffernan | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.73 per share. | 21 Jan 2020 | 275,463 | 402,086 (1%) | 0% | 5.7 | 1,578,403 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 21.84 per share. | 21 Jan 2020 | 262,587 | 139,499 (0%) | 0% | 21.8 | 5,734,900 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.56 per share. | 21 Jan 2020 | 214 | 73,342 (0%) | 0% | 21.6 | 4,614 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 23.87 per share. | 14 Jan 2020 | 1,321 | 35,716 (0%) | 0% | 23.9 | 31,532 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.30 per share. | 10 Jan 2020 | 702 | 37,037 (0%) | 0% | 23.3 | 16,357 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.58 per share. | 02 Jan 2020 | 1,091 | 171,686 (0%) | 0% | 20.6 | 22,453 | Common Stock |
| John G. Freund | None | Other type of transaction at price $ 0.00 per share. | 02 Dec 2019 | 8,625 | 8,625 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | None | Other type of transaction at price $ 0.00 per share. | 02 Dec 2019 | 574,916 | 0 (0%) | 1% | 0 | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.73 per share. | 29 Nov 2019 | 4,678 | 172,777 (0%) | 0% | 21.7 | 101,653 | Common Stock |
| John G. Freund | None | Other type of transaction at price $ 0.00 per share. | 12 Nov 2019 | 8,423 | 34,788 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | None | Other type of transaction at price $ 0.00 per share. | 12 Nov 2019 | 575,000 | 574,916 (1%) | 1% | 0 | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 19.44 per share. | 08 Nov 2019 | 25,000 | 73,556 (0%) | 0% | 19.4 | 486,000 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Nov 2019 | 25,000 | 35,378 | - | - | Stock Option (Right to Purchase) | |
| Alison B. Fleming | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.73 per share. | 08 Nov 2019 | 25,000 | 98,556 (0%) | 0% | 5.7 | 143,250 | Common Stock |
| David Hirsch | None | Sale of securities on an exchange or to another person at price $ 19.33 per share. | 08 Nov 2019 | 25,000 | 17,117 (0%) | 0% | 19.3 | 483,250 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Nov 2019 | 64,821 | 129,641 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 19.16 per share. | 07 Nov 2019 | 31,226 | 177,455 (0%) | 0% | 19.2 | 598,290 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 18.41 per share. | 07 Nov 2019 | 33,595 | 208,681 (0%) | 0% | 18.4 | 618,484 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 07 Nov 2019 | 64,821 | 242,276 (0%) | 0% | 8.2 | 532,829 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.44 per share. | 16 Sep 2019 | 736 | 43,394 (0%) | 0% | 12.4 | 9,156 | Common Stock |
| David Hirsch | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.33 per share. | 29 Aug 2019 | 19,853 | 64,223 (0%) | 0% | 9.3 | 185,228 | Common Stock |
| David Hirsch | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Aug 2019 | 19,853 | 0 | - | - | Stock Option (Right to Purchase) | |
| David Hirsch | None | Sale of securities on an exchange or to another person at price $ 11.65 per share. | 29 Aug 2019 | 22,106 | 42,117 (0%) | 0% | 11.7 | 257,535 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 11.24 per share. | 09 Aug 2019 | 919 | 177,455 (0%) | 0% | 11.2 | 10,330 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 9.04 per share. | 09 Aug 2019 | 797 | 152,904 (0%) | 0% | 9.0 | 7,205 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 11.24 per share. | 09 Aug 2019 | 1,517 | 151,387 (0%) | 0% | 11.2 | 17,051 | Common Stock |
| Michael T. Heffernan | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 11.24 per share. | 09 Aug 2019 | 4,779 | 126,623 (0%) | 0% | 11.2 | 53,716 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 11.24 per share. | 09 Aug 2019 | 1,517 | 73,556 (0%) | 0% | 11.2 | 17,051 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.35 per share. | 19 Jul 2019 | 181 | 152,107 (0%) | 0% | 10.3 | 1,873 | Common Stock |
| Michael T. Heffernan | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.35 per share. | 19 Jul 2019 | 667 | 131,402 (0%) | 0% | 10.3 | 6,903 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.35 per share. | 19 Jul 2019 | 181 | 75,073 (0%) | 0% | 10.3 | 1,873 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 11.26 per share. | 15 Jul 2019 | 25,000 | 132,069 (0%) | 0% | 11.3 | 281,500 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 12.44 per share. | 10 Jul 2019 | 1,190 | 40,596 (0%) | 0% | 12.4 | 14,804 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 12.31 per share. | 10 Jul 2019 | 2,857 | 37,739 (0%) | 0% | 12.3 | 35,170 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 13.21 per share. | 01 Jul 2019 | 1,848 | 178,374 (0%) | 0% | 13.2 | 24,412 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 12.05 per share. | 17 Jun 2019 | 2,021 | 157,069 (0%) | 0% | 12.0 | 24,353 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 11.31 per share. | 17 Jun 2019 | 22,979 | 159,090 (0%) | 0% | 11.3 | 259,892 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 11.52 per share. | 31 May 2019 | 5,851 | 190,755 (0%) | 0% | 11.5 | 67,404 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 11.59 per share. | 31 May 2019 | 7,436 | 180,222 (0%) | 0% | 11.6 | 86,183 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 11.51 per share. | 31 May 2019 | 3,097 | 187,658 (0%) | 0% | 11.5 | 35,646 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 12.74 per share. | 15 May 2019 | 18,483 | 188,586 (0%) | 0% | 12.7 | 235,473 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 13.13 per share. | 15 May 2019 | 6,517 | 182,069 (0%) | 0% | 13.1 | 85,568 | Common Stock |
| Gino Santini | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 30,148 (0%) | 0% | 0 | Common Stock | |
| Gino Santini | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| John G. Freund | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 6,960 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| Theodore R. Schroeder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| Theodore R. Schroeder | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 6,960 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 6,960 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 207,069 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| John A. Fallon | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 9,335 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 6,960 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| David Hirsch | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 9,414 | 9,414 | - | - | Stock Option (Right to Purchase) | |
| David Hirsch | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Apr 2019 | 4,707 | 44,370 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 15.87 per share. | 15 Apr 2019 | 4,808 | 202,362 (0%) | 0% | 15.9 | 76,303 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 14.91 per share. | 15 Apr 2019 | 20,192 | 207,170 (0%) | 0% | 14.9 | 301,063 | Common Stock |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2019 | 42,500 | 42,500 (0%) | 0% | 0 | Common Stock | |
| Richard Malamut | EVP and Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2019 | 85,000 | 85,000 | - | - | Stock Option (Right to Purchase) | |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 17.17 per share. | 15 Mar 2019 | 25,000 | 227,362 (0%) | 0% | 17.2 | 429,250 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.98 per share. | 15 Mar 2019 | 1,470 | 44,130 (0%) | 0% | 17.0 | 24,961 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 15.06 per share. | 15 Feb 2019 | 7,068 | 252,362 (0%) | 0% | 15.1 | 106,444 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 14.71 per share. | 15 Feb 2019 | 17,932 | 259,430 (0%) | 0% | 14.7 | 263,780 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 14.39 per share. | 08 Feb 2019 | 2,052 | 196,606 (0%) | 0% | 14.4 | 29,528 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 14.39 per share. | 08 Feb 2019 | 2,693 | 152,288 (0%) | 0% | 14.4 | 38,752 | Common Stock |
| Michael T. Heffernan | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 14.39 per share. | 08 Feb 2019 | 7,851 | 277,362 (0%) | 0% | 14.4 | 112,976 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 14.39 per share. | 08 Feb 2019 | 2,714 | 75,254 (0%) | 0% | 14.4 | 39,054 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 90,000 | 90,000 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 90,000 | 198,658 (0%) | 0% | 0 | Common Stock | |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 32,000 | 32,000 | - | - | Stock Option (Right to Purchase) | |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 32,000 | 154,981 (0%) | 0% | 0 | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 25,600 | 77,968 (0%) | 0% | 0 | Common Stock | |
| Alison B. Fleming | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 25,600 | 25,600 | - | - | Stock Option (Right to Purchase) | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 25,600 | 45,600 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 25,600 | 25,600 | - | - | Stock Option (Right to Purchase) | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 25,600 | 25,600 | - | - | Stock Option (Right to Purchase) | |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jan 2019 | 25,600 | 41,786 (0%) | 0% | 0 | Common Stock | |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.76 per share. | 18 Jan 2019 | 214 | 122,981 (0%) | 0% | 15.8 | 3,373 | Common Stock |
| Michael T. Heffernan | None | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.76 per share. | 18 Jan 2019 | 787 | 285,213 (0%) | 0% | 15.8 | 12,403 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.76 per share. | 18 Jan 2019 | 214 | 52,368 (0%) | 0% | 15.8 | 3,373 | Common Stock |
| Michael T. Heffernan | None | Sale of securities on an exchange or to another person at price $ 15.56 per share. | 15 Jan 2019 | 25,000 | 286,000 (0%) | 0% | 15.6 | 389,000 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 18.12 per share. | 17 Dec 2018 | 21,687 | 314,313 (0%) | 0% | 18.1 | 392,968 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 18.57 per share. | 17 Dec 2018 | 3,313 | 311,000 (0%) | 0% | 18.6 | 61,522 | Common Stock |
| Joseph Ciaffoni | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.19 per share. | 30 Nov 2018 | 4,683 | 108,658 (0%) | 0% | 19.2 | 89,867 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 17.05 per share. | 15 Nov 2018 | 3,600 | 336,000 (0%) | 0% | 17.1 | 61,380 | Common Stock |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 16.53 per share. | 15 Nov 2018 | 21,400 | 339,600 (0%) | 0% | 16.5 | 353,742 | Common Stock |
| John G. Freund | Director | Other type of transaction at price $ 0.00 per share. | 14 Nov 2018 | 400,000 | 1,149,916 (3%) | 1% | 0 | Common Stock | |
| John G. Freund | Director | Other type of transaction at price $ 0.00 per share. | 14 Nov 2018 | 5,859 | 26,365 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | Director | Sale of securities on an exchange or to another person at price $ 16.53 per share. | 15 Oct 2018 | 25,000 | 361,000 (1%) | 0% | 16.5 | 413,250 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.03 per share. | 23 Aug 2018 | 599 | 123,195 (0%) | 0% | 18.0 | 10,800 | Common Stock |
| Michael T. Heffernan | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.03 per share. | 23 Aug 2018 | 2,025 | 386,000 (1%) | 0% | 18.0 | 36,511 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.03 per share. | 23 Aug 2018 | 599 | 52,582 (0%) | 0% | 18.0 | 10,800 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Grant, award, or other acquisition of securities at price $ 15.84 per share. | 03 Aug 2018 | 539 | 123,975 (0%) | 0% | 15.8 | 8,538 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.15 per share. | 03 Aug 2018 | 181 | 123,794 (0%) | 0% | 20.1 | 3,647 | Common Stock |
| Michael T. Heffernan | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.15 per share. | 03 Aug 2018 | 668 | 388,025 (1%) | 0% | 20.1 | 13,460 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.15 per share. | 03 Aug 2018 | 181 | 53,181 (0%) | 0% | 20.1 | 3,647 | Common Stock |
| Scott Dreyer | EVP & Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jul 2018 | 16,186 | 16,186 (0%) | 0% | 0 | Common Stock | |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2018 | 41,418 | 41,418 | - | - | Stock Option (Right to Purchase) | |
| Joseph Ciaffoni | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2018 | 25,140 | 113,341 (0%) | 0% | 0 | Common Stock | |
| Paul Brannelly | Executive Vice President & CFO | Sale of securities on an exchange or to another person at price $ 27.50 per share. | 21 Jun 2018 | 5,100 | 128,336 (0%) | 0% | 27.5 | 140,250 | Common Stock |
| Paul Brannelly | Executive Vice President & CFO | Sale of securities on an exchange or to another person at price $ 28.35 per share. | 21 Jun 2018 | 4,900 | 123,436 (0%) | 0% | 28.4 | 138,915 | Common Stock |
| Alison B. Fleming | Chief Technology Officer | Sale of securities on an exchange or to another person at price $ 27.00 per share. | 12 Jun 2018 | 4,096 | 53,362 (0%) | 0% | 27 | 110,592 | Common Stock |
| Michael T. Heffernan | Director, Chairman, President and CEO | Sale of securities on an exchange or to another person at price $ 25.26 per share. | 11 Jun 2018 | 53,057 | 388,693 (1%) | 0% | 25.3 | 1,340,220 | Common Stock |
| Michael T. Heffernan | Director, Chairman, President and CEO | Sale of securities on an exchange or to another person at price $ 25.28 per share. | 11 Jun 2018 | 96,943 | 441,750 (1%) | 0% | 25.3 | 2,450,719 | Common Stock |
| Joseph Ciaffoni | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 23.35 per share. | 31 May 2018 | 5,617 | 109,268 (0%) | 0% | 23.4 | 131,157 | Common Stock |
| Joseph Ciaffoni | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 22.48 per share. | 31 May 2018 | 14,862 | 88,201 (0%) | 0% | 22.5 | 334,098 | Common Stock |
| Joseph Ciaffoni | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.62 per share. | 31 May 2018 | 6,205 | 103,063 (0%) | 0% | 22.6 | 140,357 | Common Stock |
| Joseph Ciaffoni | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 22.54 per share. | 31 May 2018 | 59,204 | 114,885 (0%) | 0% | 22.5 | 1,334,458 | Common Stock |
| Joseph Ciaffoni | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.22 per share. | 31 May 2018 | 64,821 | 174,089 (0%) | 0% | 8.2 | 532,829 | Common Stock |
| Joseph Ciaffoni | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 May 2018 | 64,821 | 194,462 | - | - | Stock option (right to purchase) | |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 4,506 | 4,506 | - | - | Stock Option (Right to Purchase) | |
| Gino Santini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 2,253 | 25,441 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 2,253 | 2,253 (0%) | 0% | 0 | Common Stock | |
| John G. Freund | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 4,506 | 4,506 | - | - | Stock Option (Right to Purchase) | |
| Theodore R. Schroeder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 2,253 | 2,253 (0%) | 0% | 0 | Common Stock | |
| Theodore R. Schroeder | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 4,506 | 4,506 | - | - | Stock Option (Right to Purchase) | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 2,253 | 2,253 (0%) | 0% | 0 | Common Stock | |
| Garen G. Bohlin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 4,506 | 4,506 | - | - | Stock Option (Right to Purchase) | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 2,253 | 4,628 (0%) | 0% | 0 | Common Stock | |
| John A. Fallon | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 4,506 | 4,506 | - | - | Stock Option (Right to Purchase) | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 2,253 | 2,253 (0%) | 0% | 0 | Common Stock | |
| Gwen A. Melincoff | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 4,506 | 4,506 | - | - | Stock Option (Right to Purchase) | |
| David Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 4,506 | 4,506 | - | - | Stock Option (Right to Purchase) | |
| David Hirsch | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 May 2018 | 2,253 | 27,193 (0%) | 0% | 0 | Common Stock | |
| Michael T. Heffernan | Director, Chairman, President and CEO | Sale of securities on an exchange or to another person at price $ 27.00 per share. | 10 May 2018 | 1,500 | 538,693 (1%) | 0% | 27 | 40,500 | Common Stock |
| Michael T. Heffernan | Director, Chairman, President and CEO | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 10 May 2018 | 5,600 | 540,193 (1%) | 0% | 26 | 145,600 | Common Stock |
| Michael T. Heffernan | Director, Chairman, President and CEO | Sale of securities on an exchange or to another person at price $ 26.00 per share. | 19 Apr 2018 | 44,300 | 545,893 (1%) | 0% | 26 | 1,151,800 | Common Stock |
| Michael T. Heffernan | Director, Chairman, President and CEO | Sale of securities on an exchange or to another person at price $ 26.01 per share. | 19 Apr 2018 | 100 | 545,793 (1%) | 0% | 26.0 | 2,601 | Common Stock |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2018 | 20,000 | 20,000 (0%) | 0% | 0 | Common Stock | |
| Shirley R. Kuhlmann | EVP and General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Apr 2018 | 40,000 | 40,000 | - | - | Stock Option (Right to Purchase) | |
| Alison B. Fleming | Chief Technology Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Apr 2018 | 3,917 | 0 | - | - | Stock option (right to purchase) |