2.0M XNAS Volume
XNAS 17 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 165,742 | 4,370,742 (2%) | 0% | 0 | Common Stock | |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 975,000 | 4,205,000 (2%) | 0% | 0 | Common Stock | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.50 per share. | 06 Mar 2025 | 60,984 | 4,309,758 (2%) | 0% | 1.5 | 91,354 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 80,540 | 966,902 (0%) | 0% | 0 | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 392,500 | 886,362 (0%) | 0% | 0 | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.50 per share. | 06 Mar 2025 | 31,148 | 935,754 (0%) | 0% | 1.5 | 46,660 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 66,565 | 760,938 (0%) | 0% | 0 | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 300,000 | 694,373 (0%) | 0% | 0 | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.50 per share. | 06 Mar 2025 | 26,139 | 734,799 (0%) | 0% | 1.5 | 39,156 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 385,000 | 790,198 (0%) | 0% | 0 | Common Stock | |
| Chrystal Jensen | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 69,577 | 859,775 (0%) | 0% | 0 | Common Stock | |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 1.50 per share. | 06 Mar 2025 | 27,457 | 832,318 (0%) | 0% | 1.5 | 41,131 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 545,000 | 1,450,828 (0%) | 0% | 0 | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.50 per share. | 06 Mar 2025 | 33,999 | 1,507,315 (0%) | 0% | 1.5 | 50,931 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Mar 2025 | 90,486 | 1,541,314 (0%) | 0% | 0 | Common Stock | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 57,637 | 3,253,023 (2%) | 0% | - | Common Stock | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 57,637 | 0 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 1.55 per share. | 03 Mar 2025 | 23,023 | 3,230,000 (1%) | 0% | 1.5 | 35,651 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.58 per share. | 03 Mar 2025 | 60,656 | 493,862 (0%) | 0% | 1.6 | 95,673 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 18,550 | 562,904 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.55 per share. | 03 Mar 2025 | 8,386 | 554,518 (0%) | 0% | 1.5 | 12,986 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 18,550 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 13,912 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 13,912 | 451,919 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.58 per share. | 03 Mar 2025 | 51,254 | 400,665 (0%) | 0% | 1.6 | 80,828 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.55 per share. | 03 Mar 2025 | 6,292 | 394,373 (0%) | 0% | 1.5 | 9,743 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 1.59 per share. | 03 Mar 2025 | 60,000 | 405,198 (0%) | 0% | 1.6 | 95,142 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 13,912 | 471,490 (0%) | 0% | - | Common Stock | |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 1.55 per share. | 03 Mar 2025 | 6,292 | 465,198 (0%) | 0% | 1.5 | 9,743 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 13,912 | 0 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 23,850 | 0 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 23,850 | 916,608 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.55 per share. | 03 Mar 2025 | 10,780 | 905,828 (0%) | 0% | 1.5 | 16,693 | Common Stock |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 57,637 | 57,637 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 18,550 | 18,550 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 13,912 | 13,912 | - | - | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 13,912 | 13,912 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 23,850 | 23,850 | - | - | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 1.71 per share. | 16 Dec 2024 | 16,667 | 457,578 (0%) | 0% | 1.7 | 28,501 | Common Stock |
| Dean Gregory | Director | Purchase of securities on an exchange or from another person at price $ 1.70 per share. | 13 Dec 2024 | 1,725 | 61,725 (0%) | 0% | 1.7 | 2,933 | Common Stock |
| Eric H. Bjerkholt | Director | Sale of securities on an exchange or to another person at price $ 1.78 per share. | 12 Dec 2024 | 20,000 | 162,133 (0%) | 0% | 1.8 | 35,700 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.18 per share. | 03 Sep 2024 | 28,385 | 590,365 (0%) | 0% | 2.2 | 61,919 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.15 per share. | 03 Sep 2024 | 54,272 | 536,093 (0%) | 0% | 2.2 | 116,826 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 2.06 per share. | 15 Aug 2024 | 16,667 | 474,245 (0%) | 0% | 2.1 | 34,417 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.50 per share. | 02 Aug 2024 | 21,605 | 438,007 (0%) | 0% | 2.5 | 54,013 | Common Stock |
| Dean Gregory | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2024 | 60,000 | 60,000 (0%) | 0% | 0 | Common Stock | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 147,045 (0%) | 0% | 5 | 200,000 | Common Stock |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 220,059 (0%) | 0% | 5 | 200,000 | Common Stock |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 182,133 (0%) | 0% | 5 | 200,000 | Common Stock |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 148,362 (0%) | 0% | 5 | 200,000 | Common Stock |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 163,420 (0%) | 0% | 5 | 200,000 | Common Stock |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 145,073 (0%) | 0% | 5 | 200,000 | Common Stock |
| Ann Lucena | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 112,284 (0%) | 0% | 5 | 200,000 | Common Stock |
| Hua Shan | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 05 Jun 2024 | 40,000 | 72,386 (0%) | 0% | 5 | 200,000 | Common Stock |
| Hua Shan | Director | Purchase of securities on an exchange or from another person at price $ 1.99 per share. | 13 May 2024 | 2,500 | 32,386 (0%) | 0% | 2.0 | 4,975 | Common Stock |
| Jami Dover Nachtsheim | Director | Purchase of securities on an exchange or from another person at price $ 1.79 per share. | 10 May 2024 | 2,000 | 108,362 (0%) | 0% | 1.8 | 3,578 | Common Stock |
| Daniel N. Swisher | Director | Purchase of securities on an exchange or from another person at price $ 1.88 per share. | 09 May 2024 | 2,500 | 107,045 (0%) | 0% | 1.9 | 4,689 | Common Stock |
| Witney Frank | Director | Purchase of securities on an exchange or from another person at price $ 1.89 per share. | 09 May 2024 | 20,000 | 180,059 (0%) | 0% | 1.9 | 37,800 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 16,666 | 2,368,167 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 16,666 | 0 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 12 Mar 2024 | 14,360 | 2,339,740 (1%) | 0% | 2.0 | 28,352 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.06 per share. | 12 Mar 2024 | 14,067 | 2,354,100 (1%) | 0% | 2.1 | 28,936 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 64,666 | 0 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 64,666 | 3,307,207 (2%) | 0% | - | Common Stock | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.06 per share. | 12 Mar 2024 | 62,315 | 3,244,892 (2%) | 0% | 2.1 | 128,182 | Common Stock |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.02 per share. | 12 Mar 2024 | 63,611 | 3,181,281 (1%) | 0% | 2.0 | 128,195 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 21,666 | 661,305 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.02 per share. | 12 Mar 2024 | 21,058 | 640,247 (0%) | 0% | 2.0 | 42,438 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 12 Mar 2024 | 21,497 | 618,750 (0%) | 0% | 2.0 | 42,444 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 21,666 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 16,666 | 494,727 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.06 per share. | 12 Mar 2024 | 17,377 | 477,350 (0%) | 0% | 2.1 | 35,744 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 12 Mar 2024 | 17,738 | 459,612 (0%) | 0% | 2.0 | 35,022 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 16,666 | 0 | - | - | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 2.06 per share. | 12 Mar 2024 | 17,460 | 508,736 (0%) | 0% | 2.1 | 35,915 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 12 Mar 2024 | 17,824 | 490,912 (0%) | 0% | 2.0 | 35,192 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 16,666 | 0 | - | - | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 16,666 | 526,196 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 2.06 per share. | 12 Mar 2024 | 10,203 | 501,039 (0%) | 0% | 2.1 | 20,988 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 11,666 | 0 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 11,666 | 511,242 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 12 Mar 2024 | 10,416 | 490,623 (0%) | 0% | 2.0 | 20,565 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 12 Mar 2024 | 26,794 | 878,653 (0%) | 0% | 2.0 | 52,902 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 25,000 | 931,694 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 2.06 per share. | 12 Mar 2024 | 26,247 | 905,447 (0%) | 0% | 2.1 | 53,990 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2024 | 25,000 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.40 per share. | 08 Mar 2024 | 29,378 | 478,061 (0%) | 0% | 2.4 | 70,457 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 90,000 | 2,351,501 | - | 0 | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 575,000 | 3,242,541 | - | 0 | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 200,000 | 639,639 | - | 0 | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 160,000 | 507,439 | - | 0 | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 160,000 | 509,530 | - | 0 | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 75,000 | 499,576 | - | 0 | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 240,000 | 906,694 | - | 0 | Restricted Stock Unit | |
| H. Eric Bjerkholt | Director | Purchase of securities on an exchange or from another person at price $ 1.62 per share. | 13 Dec 2023 | 10,000 | 142,133 (0%) | 0% | 1.6 | 16,200 | Common Stock |
| Ann Lucena | Director | Purchase of securities on an exchange or from another person at price $ 1.69 per share. | 22 Aug 2023 | 7,500 | 72,284 (0%) | 0% | 1.7 | 12,638 | Common Stock |
| Eric H. Bjerkholt | Director | Purchase of securities on an exchange or from another person at price $ 1.72 per share. | 21 Aug 2023 | 10,000 | 132,133 (0%) | 0% | 1.7 | 17,151 | Common Stock |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 07 Jun 2023 | 40,000 | 104,545 (0%) | 0% | 5 | 200,000 | Common Stock |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 07 Jun 2023 | 40,000 | 160,059 (0%) | 0% | 5 | 200,000 | Common Stock |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 07 Jun 2023 | 40,000 | 122,133 (0%) | 0% | 5 | 200,000 | Common Stock |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 07 Jun 2023 | 40,000 | 106,362 (0%) | 0% | 5 | 200,000 | Common Stock |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 07 Jun 2023 | 40,000 | 123,420 (0%) | 0% | 5 | 200,000 | Common Stock |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 07 Jun 2023 | 40,000 | 105,073 (0%) | 0% | 5 | 200,000 | Common Stock |
| Ann Lucena | Director | Grant, award, or other acquisition of securities at price $ 5.00 per share. | 07 Jun 2023 | 40,000 | 64,784 (0%) | 0% | 5 | 200,000 | Common Stock |
| Daniel N. Swisher | Director | Purchase of securities on an exchange or from another person at price $ 1.91 per share. | 26 May 2023 | 5,000 | 118,808 (0%) | 0% | 1.9 | 9,535 | Common Stock |
| Gail Gaumer Schulze | Director | Purchase of securities on an exchange or from another person at price $ 2.03 per share. | 24 May 2023 | 9,850 | 83,420 (0%) | 0% | 2.0 | 19,981 | Common Stock |
| Eric H. Bjerkholt | Director | Purchase of securities on an exchange or from another person at price $ 2.00 per share. | 23 May 2023 | 5,000 | 82,133 (0%) | 0% | 2 | 10,000 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 0 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 2,260,176 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 9,597 | 2,250,579 (1%) | 0% | 2.8 | 26,872 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 16,667 | 2,267,246 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 5,745 | 2,261,501 (1%) | 0% | 2.8 | 16,086 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 16,667 | 16,666 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 107,525 | 0 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 107,525 | 2,654,159 (1%) | 0% | - | Common Stock | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 37,748 | 2,616,411 (1%) | 0% | 2.8 | 105,694 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 64,667 | 2,681,078 (1%) | 0% | - | Common Stock | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 22,732 | 2,658,346 (1%) | 0% | 2.8 | 63,650 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 64,667 | 64,666 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 21,667 | 21,666 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 431,459 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 9,662 | 421,797 (0%) | 0% | 2.8 | 27,054 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 21,667 | 443,464 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 7,501 | 435,963 (0%) | 0% | 2.8 | 21,003 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 9,606 | 346,519 (0%) | 0% | 2.8 | 26,897 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 356,125 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 16,667 | 363,186 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 5,747 | 357,439 (0%) | 0% | 2.8 | 16,092 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 2.78 per share. | 12 Mar 2023 | 10,000 | 347,439 (0%) | 0% | 2.8 | 27,793 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 16,667 | 16,666 | - | - | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 16,667 | 16,666 | - | - | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 0 | - | - | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 5,758 | 349,530 (0%) | 0% | 2.8 | 16,122 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 16,667 | 355,288 (0%) | 0% | - | Common Stock | |
| Chrystal Jensen | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 9,710 | 338,621 (0%) | 0% | 2.8 | 27,188 | Common Stock |
| Chrystal Jensen | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 348,331 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 417,326 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 9,728 | 407,598 (0%) | 0% | 2.8 | 27,238 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 11,667 | 419,265 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 3,350 | 415,915 (0%) | 0% | 2.8 | 9,380 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 23,460 | 0 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 11,667 | 11,666 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 44,200 | 658,426 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 16,565 | 641,861 (0%) | 0% | 2.8 | 46,382 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 25,000 | 666,861 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 12 Mar 2023 | 8,791 | 658,070 (0%) | 0% | 2.8 | 24,615 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 44,200 | 0 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2023 | 25,000 | 25,000 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 110,000 | 2,236,716 | - | 0 | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 575,000 | 2,546,634 | - | 0 | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 185,000 | 407,999 | - | 0 | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 160,000 | 332,665 | - | 0 | Restricted Stock Unit | |
| Chrystal Jensen | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 160,000 | 324,871 | - | 0 | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 110,000 | 393,866 | - | 0 | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 240,000 | 614,226 | - | 0 | Restricted Stock Unit | |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.19 per share. | 28 Dec 2022 | 25,000 | 73,570 (0%) | 0% | 3.2 | 79,750 | Common Stock |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Dec 2022 | 25,000 | 0 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Nov 2022 | 12,500 | 0 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 3.91 per share. | 10 Nov 2022 | 12,500 | 113,808 (0%) | 0% | 3.9 | 48,875 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.19 per share. | 10 Nov 2022 | 12,500 | 126,308 (0%) | 0% | 3.2 | 39,875 | Common Stock |
| Chrystal N. Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 5.18 per share. | 15 Aug 2022 | 10,000 | 164,871 (0%) | 0% | 5.2 | 51,800 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.12 per share. | 09 Aug 2022 | 10,000 | 172,665 (0%) | 0% | 5.1 | 51,194 | Common Stock |
| Hua Shan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 29,886 | 29,886 (0%) | 0% | 0 | Common Stock | |
| Hua Shan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 58,074 | 58,074 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 39,866 | 39,866 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 20,454 | 113,808 (0%) | 0% | 0 | Common Stock | |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 20,454 | 120,059 (0%) | 0% | 0 | Common Stock | |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 39,866 | 39,866 | - | - | Option (Right to Buy) | |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 20,454 | 77,133 (0%) | 0% | 0 | Common Stock | |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 39,866 | 39,866 | - | - | Option (Right to Buy) | |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 20,454 | 66,362 (0%) | 0% | 0 | Common Stock | |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 39,866 | 39,866 | - | - | Option (Right to Buy) | |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 39,866 | 39,866 | - | - | Option (Right to Buy) | |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 20,454 | 48,570 (0%) | 0% | 0 | Common Stock | |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 39,866 | 39,866 | - | - | Option (Right to Buy) | |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 20,454 | 65,073 (0%) | 0% | 0 | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.98 per share. | 10 May 2022 | 57,335 | 222,999 (0%) | 0% | 5.0 | 285,373 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 16,667 | 33,333 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 2,117,586 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 16,152 | 2,101,434 (1%) | 0% | 5.0 | 81,400 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 2,124,204 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 8,173 | 2,116,031 (1%) | 0% | 5.0 | 41,189 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 16,667 | 2,132,698 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 5,982 | 2,126,716 (1%) | 0% | 5.0 | 30,147 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 0 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 23,460 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 267,999 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 16,152 | 251,847 (0%) | 0% | 5.0 | 81,400 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 274,617 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 8,173 | 266,444 (0%) | 0% | 5.0 | 41,189 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 21,667 | 288,111 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 7,777 | 280,334 (0%) | 0% | 5.0 | 39,192 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 0 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 23,460 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 21,667 | 43,333 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 173,535 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 16,152 | 157,383 (0%) | 0% | 5.0 | 81,400 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 180,153 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 8,173 | 171,980 (0%) | 0% | 5.0 | 41,189 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 16,667 | 188,647 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 5,982 | 182,665 (0%) | 0% | 5.0 | 30,147 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 23,460 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 16,667 | 33,333 | - | - | Restricted Stock Unit | |
| Chrystal N. Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 8,173 | 164,186 (0%) | 0% | 5.0 | 41,189 | Common Stock |
| Chrystal N. Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 165,741 (0%) | 0% | - | Common Stock | |
| Chrystal N. Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 16,152 | 149,589 (0%) | 0% | 5.0 | 81,398 | Common Stock |
| Chrystal N. Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 172,359 (0%) | 0% | - | Common Stock | |
| Chrystal N. Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 16,667 | 180,853 (0%) | 0% | - | Common Stock | |
| Chrystal N. Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 5,982 | 174,871 (0%) | 0% | 5.0 | 30,147 | Common Stock |
| Chrystal N. Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 0 | - | - | Restricted Stock Unit | |
| Chrystal N. Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 23,460 | - | - | Restricted Stock Unit | |
| Chrystal N. Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 16,667 | 33,333 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 11,667 | 23,333 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 273,344 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 16,152 | 257,192 (0%) | 0% | 5.0 | 81,400 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 279,962 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 8,173 | 271,789 (0%) | 0% | 5.0 | 41,189 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 11,667 | 283,456 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 4,188 | 279,268 (0%) | 0% | 5.0 | 21,106 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 0 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 22,770 | 23,460 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 343,248 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 25,000 | 50,000 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 42,900 | 44,200 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 45,000 | 0 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 10,185 | 369,414 (0%) | 0% | 5.0 | 51,327 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 25,000 | 379,599 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 15,398 | 354,599 (0%) | 0% | 5.0 | 77,600 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2022 | 42,900 | 369,997 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 5.04 per share. | 12 Mar 2022 | 16,151 | 327,097 (0%) | 0% | 5.0 | 81,393 | Common Stock |
| Jami Dover Nachtsheim | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 5,127 | 45,908 (0%) | 0% | - | Common Stock | |
| Jami Dover Nachtsheim | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2022 | 5,127 | 0 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 45,000 | 2,072,586 | - | 0 | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 90,000 | 90,000 | - | - | Option (Right to Buy) | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 140,000 | 140,000 | - | - | Option (Right to Buy) | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 70,000 | 222,999 | - | 0 | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 52,500 | 128,535 | - | 0 | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 105,000 | 105,000 | - | - | Option (Right to Buy) | |
| Chrystal N. Menard | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 52,500 | 120,741 | - | 0 | Restricted Stock Unit | |
| Chrystal N. Menard | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 105,000 | 105,000 | - | - | Option (Right to Buy) | |
| Carol M. Moore | SVP Reg. & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 45,000 | 228,344 | - | 0 | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 90,000 | 90,000 | - | - | Option (Right to Buy) | |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 90,000 | 298,248 | - | 0 | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 180,000 | 180,000 | - | - | Option (Right to Buy) | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2022 | 380,000 | 0 | - | - | Option (Right to Buy) | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 5.73 per share. | 25 Feb 2022 | 93,000 | 1,594,018 (0%) | 0% | 5.7 | 532,648 | Common Stock |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2022 | 217,500 | 1,811,518 (1%) | 0% | 0 | Common Stock | |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2022 | 435,000 | 435,000 | - | - | Option (Right to Buy) | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.75 per share. | 25 Feb 2022 | 380,000 | 1,902,281 (1%) | 0% | 3.8 | 1,425,000 | Common Stock |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 5.69 per share. | 25 Feb 2022 | 215,263 | 1,687,018 (1%) | 0% | 5.7 | 1,224,394 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 7.00 per share. | 03 Jan 2022 | 19,059 | 181,276 (0%) | 0% | 7.0 | 133,417 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2022 | 19,059 | 150,941 | - | - | Option (Right to Buy) | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.66 per share. | 03 Jan 2022 | 19,059 | 200,335 (0%) | 0% | 3.7 | 69,756 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2021 | 40,000 | 5,000 | - | - | Option (Right to Buy) | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.75 per share. | 13 Dec 2021 | 40,000 | 2,022,586 (1%) | 0% | 3.8 | 150,000 | Common Stock |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.86 per share. | 09 Nov 2021 | 25,000 | 53,116 (0%) | 0% | 2.9 | 71,500 | Common Stock |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Nov 2021 | 25,000 | 0 | - | - | Option (Right to Buy) | |
| Gail Gaumer Schulze | Director | Sale of securities on an exchange or to another person at price $ 7.54 per share. | 09 Nov 2021 | 25,000 | 28,116 (0%) | 0% | 7.5 | 188,430 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 7.94 per share. | 05 Nov 2021 | 110,000 | 181,276 (0%) | 0% | 7.9 | 873,191 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Nov 2021 | 110,000 | 0 | - | - | Option (Right to Buy) | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.75 per share. | 05 Nov 2021 | 110,000 | 289,555 (0%) | 0% | 3.8 | 412,500 | Common Stock |
| Timothy L. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Sep 2021 | 4,296 | 0 | - | - | Restricted Stock Unit | |
| Timothy L. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Sep 2021 | 4,296 | 44,619 (0%) | 0% | - | Common Stock | |
| Ann Lucena | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Aug 2021 | 24,784 | 24,784 (0%) | 0% | 0 | Common Stock | |
| Ann Lucena | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Aug 2021 | 49,769 | 49,769 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 6.25 per share. | 04 Aug 2021 | 12,877 | 93,354 (0%) | 0% | 6.2 | 80,481 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Aug 2021 | 12,877 | 0 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.86 per share. | 04 Aug 2021 | 12,877 | 106,231 (0%) | 0% | 2.9 | 36,828 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Aug 2021 | 100,000 | 0 | - | - | Option (Right to Buy) | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 03 Aug 2021 | 100,000 | 1,518,672 (0%) | 0% | 2.1 | 208,000 | Common Stock |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 17,525 | 93,354 (0%) | 0% | 0 | Common Stock | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 35,295 | 35,295 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 15,961 | 0 | - | - | Restricted Stock Unit | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 15,961 | 75,829 (0%) | 0% | - | Common Stock | |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 14,888 | 99,605 (0%) | 0% | 0 | Common Stock | |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 29,983 | 29,983 | - | - | Option (Right to Buy) | |
| Witney Frank | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 0 | - | - | Restricted Stock Unit | |
| Witney Frank | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 84,717 (0%) | 0% | - | Common Stock | |
| Eric H. Bjerkholt | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 41,791 (0%) | 0% | - | Common Stock | |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 29,983 | 29,983 | - | - | Option (Right to Buy) | |
| Eric H. Bjerkholt | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 0 | - | - | Restricted Stock Unit | |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 14,888 | 56,679 (0%) | 0% | 0 | Common Stock | |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 29,983 | 29,983 | - | - | Option (Right to Buy) | |
| Jami Dover Nachtsheim | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 0 | - | - | Restricted Stock Unit | |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 14,888 | 40,781 (0%) | 0% | 0 | Common Stock | |
| Jami Dover Nachtsheim | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 25,893 (0%) | 0% | - | Common Stock | |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 0 | - | - | Restricted Stock Unit | |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 213,993 (0%) | 0% | - | Common Stock | |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 13,228 (0%) | 0% | - | Common Stock | |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 29,983 | 29,983 | - | - | Option (Right to Buy) | |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 0 | - | - | Restricted Stock Unit | |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 14,888 | 28,116 (0%) | 0% | 0 | Common Stock | |
| Timothy L. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 0 | - | - | Restricted Stock Unit | |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 29,983 | 29,983 | - | - | Option (Right to Buy) | |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2021 | 14,888 | 40,323 (0%) | 0% | 0 | Common Stock | |
| Timothy L. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2021 | 13,228 | 25,435 (0%) | 0% | - | Common Stock | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 May 2021 | 5,000 | 0 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 5.75 per share. | 18 May 2021 | 5,000 | 59,868 (0%) | 0% | 5.7 | 28,735 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.90 per share. | 18 May 2021 | 5,000 | 64,868 (0%) | 0% | 2.9 | 14,500 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Apr 2021 | 25,200 | 0 | - | - | Option (Right to Buy) | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.66 per share. | 30 Apr 2021 | 25,200 | 1,982,586 (1%) | 0% | 3.7 | 92,232 | Common Stock |
| William M. Greenman | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.35 per share. | 16 Apr 2021 | 233,859 | 1,418,672 (0%) | 0% | 6.4 | 1,485,005 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Apr 2021 | 550,000 | 0 | - | - | Option (Right to Buy) | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.70 per share. | 16 Apr 2021 | 550,000 | 1,652,531 (1%) | 0% | 2.7 | 1,485,000 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 45,000 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 1,913,391 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 1,958,391 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 15,786 | 1,942,605 (1%) | 0% | 6.4 | 100,678 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 1,965,375 (1%) | 0% | - | Common Stock | |
| Laurence M. Corash | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 7,989 | 1,957,386 (1%) | 0% | 6.4 | 50,951 | Common Stock |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 0 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 46,230 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 52,484 | 1,102,531 (0%) | 0% | 6.4 | 334,727 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 151,667 | 151,666 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 104,363 | 211,887 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 71,666 | 1,002,908 (0%) | 0% | - | Common Stock | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 27,651 | 975,257 (0%) | 0% | 6.4 | 176,350 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 151,667 | 1,126,924 (0%) | 0% | - | Common Stock | |
| William M. Greenman | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 76,272 | 1,050,652 (0%) | 0% | 6.4 | 486,440 | Common Stock |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 104,363 | 1,155,015 (0%) | 0% | - | Common Stock | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 71,666 | 0 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 115,301 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 5,556 | 109,745 (0%) | 0% | 6.4 | 35,435 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 154,745 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 15,786 | 138,959 (0%) | 0% | 6.4 | 100,678 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 161,729 (0%) | 0% | - | Common Stock | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 7,989 | 153,740 (0%) | 0% | 6.4 | 50,951 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 0 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 45,000 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 46,230 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 57,596 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 46,230 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 45,000 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 0 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 6.34 per share. | 12 Mar 2021 | 20,000 | 76,035 (0%) | 0% | 6.3 | 126,780 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 7,989 | 96,035 (0%) | 0% | 6.4 | 50,951 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 104,024 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 15,786 | 81,254 (0%) | 0% | 6.4 | 100,678 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 97,040 (0%) | 0% | - | Common Stock | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 5,556 | 52,040 (0%) | 0% | 6.4 | 35,435 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 46,230 | - | - | Restricted Stock Unit | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 45,000 | - | - | Restricted Stock Unit | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 0 | - | - | Restricted Stock Unit | |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 7,989 | 105,853 (0%) | 0% | 6.4 | 50,951 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 113,842 (0%) | 0% | - | Common Stock | |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 15,786 | 91,072 (0%) | 0% | 6.4 | 100,678 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 106,858 (0%) | 0% | - | Common Stock | |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 5,556 | 61,858 (0%) | 0% | 6.4 | 35,435 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 67,414 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 46,230 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 45,000 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 0 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 7,989 | 179,555 (0%) | 0% | 6.4 | 50,951 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 22,770 | 187,544 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 15,786 | 164,774 (0%) | 0% | 6.4 | 100,678 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 180,560 (0%) | 0% | - | Common Stock | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 5,556 | 135,560 (0%) | 0% | 6.4 | 35,435 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 141,116 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 0 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 15,833 | 153,888 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 5,556 | 148,332 (0%) | 0% | 6.4 | 35,435 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 193,332 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 15,786 | 177,546 (0%) | 0% | 6.4 | 100,678 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 42,900 | 220,446 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 12 Mar 2021 | 15,807 | 204,639 (0%) | 0% | 6.4 | 100,812 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 45,000 | 45,000 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Mar 2021 | 42,900 | 87,100 | - | - | Restricted Stock Unit | |
| Jami Dover Nachtsheim | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2021 | 5,127 | 12,665 (0%) | 0% | - | Common Stock | |
| Jami Dover Nachtsheim | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Mar 2021 | 5,127 | 5,127 | - | - | Restricted Stock Unit | |
| Laurence M. Corash | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 100,000 | 100,000 | - | - | Option (Right to Buy) | |
| Laurence M. Corash | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 50,000 | 50,000 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 380,000 | 380,000 | - | - | Option (Right to Buy) | |
| William M. Greenman | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 194,000 | 194,000 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 65,000 | 65,000 | - | - | Restricted Stock Unit | |
| Kevin D. Green | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 130,000 | 130,000 | - | - | Option (Right to Buy) | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 50,000 | 50,000 | - | - | Restricted Stock Unit | |
| Richard J. Benjamin | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 100,000 | 100,000 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 50,000 | 50,000 | - | - | Restricted Stock Unit | |
| Chrystal Menard | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 100,000 | 100,000 | - | - | Option (Right to Buy) | |
| Carol M. Moore | SVP Reg. & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 70,000 | 70,000 | - | - | Option (Right to Buy) | |
| Carol M. Moore | SVP Reg. & Quality | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 35,000 | 35,000 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 75,000 | 75,000 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 150,000 | 150,000 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2021 | 10,000 | 5,000 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.90 per share. | 16 Feb 2021 | 10,000 | 69,868 (0%) | 0% | 2.9 | 29,000 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 7.78 per share. | 16 Feb 2021 | 10,000 | 59,868 (0%) | 0% | 7.8 | 77,797 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.32 per share. | 08 Feb 2021 | 3,958 | 52,543 (0%) | 0% | 4.3 | 17,099 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.33 per share. | 08 Feb 2021 | 4,167 | 52,752 (0%) | 0% | 4.3 | 18,043 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2021 | 3,958 | 29,688 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Feb 2021 | 4,167 | 6,250 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 08 Feb 2021 | 3,958 | 48,585 (0%) | 0% | 8 | 31,664 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 08 Feb 2021 | 4,167 | 48,585 (0%) | 0% | 8 | 33,336 | Common Stock |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.40 per share. | 22 Dec 2020 | 30,000 | 240,101 (0%) | 0% | 5.4 | 162,000 | Common Stock |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2020 | 30,000 | 0 | - | - | Option (Right to Buy) | |
| Timothy B. Anderson | Director | Sale of securities on an exchange or to another person at price $ 8.50 per share. | 22 Dec 2020 | 9,336 | 200,765 (0%) | 0% | 8.5 | 79,356 | Common Stock |
| Timothy B. Anderson | Director | Sale of securities on an exchange or to another person at price $ 8.25 per share. | 22 Dec 2020 | 30,000 | 210,101 (0%) | 0% | 8.3 | 247,500 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 22 Dec 2020 | 68,516 | 48,585 (0%) | 0% | 8 | 548,128 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.46 per share. | 22 Dec 2020 | 68,516 | 117,101 (0%) | 0% | 4.5 | 305,581 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 22 Dec 2020 | 57,395 | 48,585 (0%) | 0% | 8 | 459,160 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.32 per share. | 22 Dec 2020 | 57,395 | 105,980 (0%) | 0% | 4.3 | 247,946 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 22 Dec 2020 | 85,416 | 48,585 (0%) | 0% | 8 | 683,328 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.33 per share. | 22 Dec 2020 | 85,416 | 134,001 (0%) | 0% | 4.3 | 369,851 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2020 | 68,516 | 0 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2020 | 57,395 | 33,646 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2020 | 85,416 | 10,417 | - | - | Option (Right to Buy) | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.33 per share. | 22 Dec 2020 | 2,668 | 137,671 (0%) | 0% | 4.3 | 11,552 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 22 Dec 2020 | 53,437 | 135,003 (0%) | 0% | 8 | 427,496 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.32 per share. | 22 Dec 2020 | 53,437 | 188,440 (0%) | 0% | 4.3 | 230,848 | Common Stock |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2020 | 2,668 | 28,437 | - | - | Option (Right to Buy) | |
| Vivek K. Jayaraman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Dec 2020 | 53,437 | 41,563 | - | - | Option (Right to Buy) | |
| Vivek K. Jayaraman | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 22 Dec 2020 | 2,668 | 135,003 (0%) | 0% | 8 | 21,344 | Common Stock |
| Gail Gaumer Schulze | Director | Sale of securities on an exchange or to another person at price $ 7.48 per share. | 14 Dec 2020 | 15,000 | 47,393 (0%) | 0% | 7.5 | 112,128 | Common Stock |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2020 | 15,000 | 0 | - | - | Option (Right to Buy) | |
| Gail Gaumer Schulze | Director | Sale of securities on an exchange or to another person at price $ 7.27 per share. | 14 Dec 2020 | 47,393 | 0 (0%) | 0% | 7.3 | 344,689 | Common Stock |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.48 per share. | 14 Dec 2020 | 15,000 | 62,393 (0%) | 0% | 2.5 | 37,200 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.33 per share. | 11 Dec 2020 | 4,167 | 52,742 (0%) | 0% | 4.3 | 18,043 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2020 | 21,875 | 0 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2020 | 11,362 | 68,516 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2020 | 3,959 | 91,041 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2020 | 4,167 | 95,833 | - | - | Option (Right to Buy) | |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 11 Dec 2020 | 21,875 | 48,585 (0%) | 0% | 8 | 175,000 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.46 per share. | 11 Dec 2020 | 21,875 | 70,460 (0%) | 0% | 4.5 | 97,563 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 11 Dec 2020 | 11,362 | 48,585 (0%) | 0% | 8 | 90,896 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.46 per share. | 11 Dec 2020 | 11,362 | 59,947 (0%) | 0% | 4.5 | 50,675 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 11 Dec 2020 | 3,959 | 48,585 (0%) | 0% | 8 | 31,672 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.32 per share. | 11 Dec 2020 | 3,959 | 52,544 (0%) | 0% | 4.3 | 17,103 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 11 Dec 2020 | 4,167 | 48,585 (0%) | 0% | 8 | 33,336 | Common Stock |
| Vivek K. Jayaraman | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 11 Dec 2020 | 18,895 | 160,003 (0%) | 0% | 8 | 151,160 | Common Stock |
| Vivek K. Jayaraman | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2020 | 18,895 | 31,105 | - | - | Option (Right to Buy) | |
| Vivek K. Jayaraman | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 11 Dec 2020 | 25,000 | 135,003 (0%) | 0% | 8 | 200,000 | Common Stock |
| Vivek K. Jayaraman | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.33 per share. | 11 Dec 2020 | 18,895 | 178,898 (0%) | 0% | 4.3 | 81,815 | Common Stock |
| Daniel N. Swisher | Director | Sale of securities on an exchange or to another person at price $ 6.25 per share. | 17 Nov 2020 | 10,000 | 59,868 (0%) | 0% | 6.3 | 62,505 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Nov 2020 | 10,000 | 15,000 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.90 per share. | 17 Nov 2020 | 10,000 | 69,868 (0%) | 0% | 2.9 | 29,000 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.51 per share. | 10 Nov 2020 | 2,143 | 130,253 (0%) | 0% | 5.5 | 11,800 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 10 Nov 2020 | 30,785 | 99,468 (0%) | 0% | 5.5 | 169,062 | Common Stock |
| Eric H. Bjerkholt | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Oct 2020 | 4,281 | 28,563 (0%) | 0% | - | Common Stock | |
| Eric H. Bjerkholt | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Oct 2020 | 4,281 | 4,281 | - | - | Restricted Stock Unit | |
| Timothy L. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Sep 2020 | 4,296 | 12,207 (0%) | 0% | - | Common Stock | |
| Timothy L. Moore | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Sep 2020 | 4,296 | 4,296 | - | - | Restricted Stock Unit | |
| Vivek K. Jayaraman | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Aug 2020 | 18,750 | 160,003 (0%) | 0% | - | Common Stock | |
| Vivek K. Jayaraman | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Aug 2020 | 18,750 | 0 | - | - | Restricted Stock Unit | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2020 | 100,000 | 0 | - | - | Option (Right to Buy) | |
| William M. Greenman | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.00 per share. | 26 Aug 2020 | 100,000 | 925,849 (0%) | 0% | 3 | 300,000 | Common Stock |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2020 | 23,703 | 0 | - | - | Option (Right to Buy) | |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.80 per share. | 24 Aug 2020 | 23,703 | 226,109 (0%) | 0% | 4.8 | 113,774 | Common Stock |
| Timothy B. Anderson | Director | Sale of securities on an exchange or to another person at price $ 7.90 per share. | 24 Aug 2020 | 16,008 | 210,101 (0%) | 0% | 7.9 | 126,463 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.72 per share. | 24 Aug 2020 | 100,000 | 141,763 (0%) | 0% | 4.7 | 472,000 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2020 | 100,000 | 100,000 | - | - | Option (Right to Buy) | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.90 per share. | 24 Aug 2020 | 100,000 | 41,763 (0%) | 0% | 7.9 | 790,000 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.00 per share. | 12 Aug 2020 | 30,000 | 141,751 (0%) | 0% | 3 | 90,000 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2020 | 30,000 | 0 | - | - | Option (Right to Buy) | |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 12 Aug 2020 | 21,621 | 120,130 (0%) | 0% | 6.9 | 148,752 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.99 per share. | 10 Aug 2020 | 3,585 | 132,396 (0%) | 0% | 7.0 | 25,044 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 10 Aug 2020 | 80,000 | 200,981 (0%) | 0% | 2.1 | 166,400 | Common Stock |
| Kevin D. Green | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Aug 2020 | 80,000 | 0 | - | - | Option (Right to Buy) | |
| Kevin D. Green | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.96 per share. | 10 Aug 2020 | 65,000 | 135,981 (0%) | 0% | 7.0 | 452,634 | Common Stock |
| Timothy B. Anderson | Director | Sale of securities on an exchange or to another person at price $ 7.10 per share. | 07 Aug 2020 | 10,223 | 202,406 (0%) | 0% | 7.1 | 72,583 | Common Stock |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Aug 2020 | 43,800 | 0 | - | - | Option (Right to Buy) | |
| Timothy B. Anderson | Director | Sale of securities on an exchange or to another person at price $ 7.12 per share. | 07 Aug 2020 | 29,853 | 212,629 (0%) | 0% | 7.1 | 212,568 | Common Stock |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.34 per share. | 07 Aug 2020 | 43,800 | 242,482 (0%) | 0% | 4.3 | 190,092 | Common Stock |
| Chrystal Menard | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 7.07 per share. | 07 Aug 2020 | 23,621 | 48,585 (0%) | 0% | 7.1 | 166,930 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Jul 2020 | 31,666 | 23,750 | - | - | Option (Right to Buy) | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Jul 2020 | 22,917 | 25,000 | - | - | Option (Right to Buy) | |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Jul 2020 | 100,000 | 200,000 | - | - | Option (Right to Buy) | |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.20 per share. | 07 Jul 2020 | 31,666 | 41,763 (0%) | 0% | 7.2 | 228,005 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.32 per share. | 07 Jul 2020 | 31,666 | 73,429 (0%) | 0% | 4.3 | 136,797 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.20 per share. | 07 Jul 2020 | 22,917 | 41,763 (0%) | 0% | 7.2 | 165,009 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.33 per share. | 07 Jul 2020 | 22,917 | 64,680 (0%) | 0% | 4.3 | 99,231 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.72 per share. | 07 Jul 2020 | 100,000 | 141,763 (0%) | 0% | 4.7 | 472,000 | Common Stock |
| Richard J. Benjamin | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.20 per share. | 07 Jul 2020 | 100,000 | 41,763 (0%) | 0% | 7.2 | 720,030 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Sale of securities on an exchange or to another person at price $ 7.00 per share. | 25 Jun 2020 | 130,000 | 111,751 (0%) | 0% | 7 | 910,000 | Common Stock |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jun 2020 | 130,000 | 0 | - | - | Option (Right to Buy) | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.08 per share. | 25 Jun 2020 | 130,000 | 241,751 (0%) | 0% | 2.1 | 270,400 | Common Stock |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 13,958 | 0 | - | - | Restricted Stock Unit | |
| Daniel N. Swisher | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 13,958 | 59,868 (0%) | 0% | - | Common Stock | |
| Witney Frank | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 11,184 | 71,489 (0%) | 0% | - | Common Stock | |
| Witney Frank | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 11,184 | 0 | - | - | Restricted Stock Unit | |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 11,184 | 198,682 (0%) | 0% | - | Common Stock | |
| Timothy B. Anderson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 11,184 | 0 | - | - | Restricted Stock Unit | |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 11,184 | 0 | - | - | Restricted Stock Unit | |
| Gail Gaumer Schulze | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2020 | 11,184 | 47,393 (0%) | 0% | - | Common Stock | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 34,001 | 34,001 | - | - | Option (Right to Buy) | |
| Daniel N. Swisher | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 15,961 | 15,961 | - | - | Restricted Stock Unit | |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 13,228 | 13,228 | - | - | Restricted Stock Unit | |
| Witney Frank | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 28,177 | 28,177 | - | - | Option (Right to Buy) | |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 28,177 | 28,177 | - | - | Option (Right to Buy) | |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 13,228 | 13,228 | - | - | Restricted Stock Unit | |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 13,228 | 13,228 | - | - | Restricted Stock Unit | |
| Jami Dover Nachtsheim | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 28,177 | 28,177 | - | - | Option (Right to Buy) | |
| Timothy B. Anderson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 13,228 | 13,228 | - | - | Restricted Stock Unit | |
| Timothy B. Anderson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 28,177 | 28,177 | - | - | Option (Right to Buy) | |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 28,177 | 28,177 | - | - | Option (Right to Buy) | |
| Gail Gaumer Schulze | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 13,228 | 13,228 | - | - | Restricted Stock Unit | |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 28,177 | 28,177 | - | - | Option (Right to Buy) | |
| Timothy L. Moore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2020 | 13,228 | 13,228 | - | - | Restricted Stock Unit | |
| Carol M. Moore | SVP Reg. & Quality | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Jun 2020 | 30,000 | 30,000 | - | - | Option (Right to Buy) |