77,410 XNAS Volume
XNAS 11 Apr, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2025 | 1,693 | 8,465 (0%) | 0% | - | Common Stock | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Mar 2025 | 1,693 | 11,852 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 34 | 387 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 31 | 1,339 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 34 | 1,373 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 31 | 229 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 217 | 2,408 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 162 | 3,887 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 217 | 4,104 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 162 | 1,142 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 34 | 387 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 31 | 229 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 34 | 1,873 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 31 | 1,839 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 31 | 229 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 31 | 1,557 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 34 | 1,591 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2025 | 34 | 387 | - | - | Restricted Stock Units | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 1,693 | 6,772 (0%) | 0% | - | Common Stock | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2025 | 1,693 | 13,545 | - | - | Restricted Stock Units | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2025 | 27,089 | 81,267 (0%) | 0% | - | Common Stock | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2025 | 27,089 | 243,810 | - | - | Restricted Stock Units | |
| Rajiv Patni | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 44,000 | 44,000 | - | - | Stock Option (right to buy) | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2024 | 27,089 | 54,178 (0%) | 0% | - | Common Stock | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2024 | 27,089 | 270,899 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 562 | 5,064 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 521 | 20,800 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 562 | 21,362 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.36 per share. | 14 Dec 2024 | 205 | 21,157 (0%) | 0% | 0.4 | 74 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.36 per share. | 14 Dec 2024 | 372 | 20,932 (0%) | 0% | 0.4 | 133 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 521 | 2,606 | - | - | Restricted Stock Units | |
| Vincent J. O'Neill | See Remarks | 14 Dec 2024 | 521 | 20,122 (0%) | 0% | - | Common Stock | ||
| Vincent J. O'Neill | See Remarks | 14 Dec 2024 | 521 | 2,606 | - | - | Restricted Stock Units | ||
| Vincent J. O'Neill | See Remarks | 14 Dec 2024 | 165 | 19,957 (0%) | 0% | 0.4 | 58 | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 3,500 | 31,500 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 2,610 | 13,049 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.36 per share. | 14 Dec 2024 | 983 | 60,920 (0%) | 0% | 0.4 | 358 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.36 per share. | 14 Dec 2024 | 2,134 | 59,605 (0%) | 0% | 0.4 | 773 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 3,500 | 61,903 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 2,610 | 58,403 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 521 | 28,799 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 562 | 5,064 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 521 | 2,606 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.35 per share. | 14 Dec 2024 | 225 | 28,931 (0%) | 0% | 0.4 | 79 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.36 per share. | 14 Dec 2024 | 205 | 29,156 (0%) | 0% | 0.4 | 73 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 562 | 29,361 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 562 | 5,064 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 521 | 24,291 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 562 | 24,853 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 0.36 per share. | 14 Dec 2024 | 210 | 24,643 (0%) | 0% | 0.4 | 75 | Common Stock |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 0.35 per share. | 14 Dec 2024 | 220 | 24,423 (0%) | 0% | 0.4 | 78 | Common Stock |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2024 | 521 | 2,606 | - | - | Restricted Stock Units | |
| David J. Mack | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 325,077 | 325,077 | - | - | Restricted Stock Units | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Nov 2024 | 27,089 | 27,089 (0%) | 0% | - | Common Stock | |
| David J. Mack | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Nov 2024 | 27,089 | 297,988 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.55 per share. | 17 Sep 2024 | 7,175 | 20,279 (0%) | 0% | 0.5 | 3,946 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Sep 2024 | 21,250 | 27,454 (0%) | 0% | - | Common Stock | |
| Vincent J. O'Neill | See Remarks | 17 Sep 2024 | 21,250 | 25,157 (0%) | 0% | - | Common Stock | ||
| Vincent J. O'Neill | See Remarks | 17 Sep 2024 | 5,556 | 19,601 (0%) | 0% | 0.6 | 3,056 | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.55 per share. | 17 Sep 2024 | 7,175 | 28,278 (0%) | 0% | 0.5 | 3,946 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Sep 2024 | 21,250 | 35,453 (0%) | 0% | - | Common Stock | |
| Matthew T. Wiley | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.55 per share. | 17 Sep 2024 | 6,272 | 19,011 (0%) | 0% | 0.6 | 3,450 | Common Stock |
| Matthew T. Wiley | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Sep 2024 | 21,250 | 25,283 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 0.55 per share. | 17 Sep 2024 | 6,863 | 23,770 (0%) | 0% | 0.6 | 3,775 | Common Stock |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Sep 2024 | 21,250 | 30,633 (0%) | 0% | - | Common Stock | |
| Matthew T. Wiley | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2024 | 750 | 4,248 (0%) | 0% | - | Common Stock | |
| Matthew T. Wiley | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Sep 2024 | 750 | 7,500 | - | - | Restricted Stock Units | |
| Matthew T. Wiley | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.69 per share. | 15 Sep 2024 | 215 | 4,033 (0%) | 0% | 0.7 | 149 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.69 per share. | 14 Sep 2024 | 356 | 6,204 (0%) | 0% | 0.7 | 246 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 563 | 6,560 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 521 | 5,997 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 563 | 5,625 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 521 | 3,127 | - | - | Restricted Stock Units | |
| Vincent J. O'Neill | See Remarks | 14 Sep 2024 | 521 | 4,045 (0%) | 0% | - | Common Stock | ||
| Vincent J. O'Neill | See Remarks | 14 Sep 2024 | 521 | 3,127 | - | - | Restricted Stock Units | ||
| Vincent J. O'Neill | See Remarks | 14 Sep 2024 | 138 | 3,907 (0%) | 0% | 0.7 | 95 | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 3,500 | 53,648 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.69 per share. | 14 Sep 2024 | 832 | 52,816 (0%) | 0% | 0.7 | 573 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.69 per share. | 14 Sep 2024 | 1,150 | 51,666 (0%) | 0% | 0.7 | 794 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 2,609 | 15,657 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 3,500 | 35,000 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 2,609 | 50,148 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 521 | 13,995 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 563 | 5,625 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 521 | 3,127 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.69 per share. | 14 Sep 2024 | 355 | 14,203 (0%) | 0% | 0.7 | 245 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 563 | 14,558 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 521 | 8,915 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 563 | 9,478 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 0.69 per share. | 14 Sep 2024 | 345 | 9,133 (0%) | 0% | 0.7 | 238 | Common Stock |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 521 | 3,127 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2024 | 563 | 5,625 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 1,875 | 1,875 | - | - | Stock Option (right to buy) | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 625 | 625 | - | - | Restricted Stock Units | |
| Vincent J. O'Neill | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 1,875 | 1,875 | - | - | Stock Option (right to buy) | |
| Vimal Mehta | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 6,250 | 6,250 | - | - | Stock Option (right to buy) | |
| Frank D. Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 1,875 | 1,875 | - | - | Stock Option (right to buy) | |
| Matthew T. Wiley | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 1,875 | 1,875 | - | - | Stock Option (right to buy) | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 1,875 | 1,875 | - | - | Stock Option (right to buy) | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jul 2024 | 625 | 625 | - | - | Restricted Stock Units | |
| Matthew T. Wiley | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2024 | 750 | 3,742 (0%) | 0% | - | Common Stock | |
| Matthew T. Wiley | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2024 | 750 | 8,250 | - | - | Restricted Stock Units | |
| Matthew T. Wiley | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.26 per share. | 15 Jun 2024 | 244 | 3,498 (0%) | 0% | 1.3 | 308 | Common Stock |
| Matthew T. Wiley | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2024 | 750 | 8,250 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.26 per share. | 14 Jun 2024 | 372 | 5,476 (0%) | 0% | 1.3 | 470 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 562 | 5,848 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 521 | 5,286 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 562 | 6,188 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 521 | 3,648 | - | - | Restricted Stock Units | |
| Vincent J. O'Neill | See Remarks | 14 Jun 2024 | 521 | 3,648 | - | - | Restricted Stock Units | ||
| Vincent J. O'Neill | See Remarks | 14 Jun 2024 | 521 | 3,679 (0%) | 0% | - | Common Stock | ||
| Vincent J. O'Neill | See Remarks | 14 Jun 2024 | 155 | 3,524 (0%) | 0% | 1.3 | 199 | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,500 | 49,673 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 2,609 | 18,266 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.28 per share. | 14 Jun 2024 | 2,134 | 47,539 (0%) | 0% | 1.3 | 2,739 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 2,609 | 46,173 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,500 | 38,500 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 562 | 13,846 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 521 | 13,284 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.28 per share. | 14 Jun 2024 | 372 | 13,474 (0%) | 0% | 1.3 | 476 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 521 | 3,648 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 562 | 6,188 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 521 | 8,193 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 562 | 6,188 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 521 | 3,648 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 1.26 per share. | 14 Jun 2024 | 361 | 8,394 (0%) | 0% | 1.3 | 456 | Common Stock |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 562 | 8,755 (0%) | 0% | - | Common Stock | |
| Peter Mueller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Other type of transaction at price $ 0.00 per share. | 10 Jun 2024 | 17,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Sandeep Laumas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| June Bray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Jun 2024 | 283,122 | 0 (0%) | 1% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Jun 2024 | 609,221 | 7,937,529 (43%) | 3% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.58 per share. | 04 Jun 2024 | 126,014 | 7,685,501 (42%) | 0% | 1.6 | 199,619 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.63 per share. | 04 Jun 2024 | 126,014 | 7,811,515 (43%) | 0% | 1.6 | 205,516 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Jun 2024 | 283,123 | 283,122 (1%) | 1% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 04 Jun 2024 | 120 | 120 | - | - | Call Options (obligation to sell) | |
| Matthew T. Wiley | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2024 | 3,000 | 9,000 | - | - | Restricted Stock Units | |
| Matthew T. Wiley | CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 2.63 per share. | 15 Mar 2024 | 1,008 | 2,992 (0%) | 0% | 2.6 | 2,656 | Common Stock |
| Matthew T. Wiley | CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Mar 2024 | 3,000 | 3,000 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 521 | 4,169 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,250 | 6,750 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 521 | 3,584 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,250 | 5,834 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.64 per share. | 14 Mar 2024 | 1,069 | 4,765 (0%) | 0% | 2.6 | 2,817 | Common Stock |
| Vincent J. O'Neill | See Remarks | 14 Mar 2024 | 521 | 4,169 | - | - | Restricted Stock Units | ||
| Vincent J. O'Neill | See Remarks | 14 Mar 2024 | 2,250 | 6,750 | - | - | Restricted Stock Units | ||
| Vincent J. O'Neill | See Remarks | 14 Mar 2024 | 165 | 5,408 (0%) | 0% | 2.6 | 432 | Common Stock | |
| Vincent J. O'Neill | See Remarks | 14 Mar 2024 | 2,250 | 5,573 (0%) | 0% | - | Common Stock | ||
| Vincent J. O'Neill | See Remarks | 14 Mar 2024 | 521 | 3,323 (0%) | 0% | - | Common Stock | ||
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 2.62 per share. | 14 Mar 2024 | 4,439 | 43,564 (0%) | 0% | 2.6 | 11,651 | Common Stock |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,610 | 20,875 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 14,000 | 42,000 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,610 | 34,832 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 14,000 | 48,832 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 2.62 per share. | 14 Mar 2024 | 829 | 48,003 (0%) | 0% | 2.6 | 2,172 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 521 | 4,169 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,250 | 6,750 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 521 | 11,580 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,250 | 13,830 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.64 per share. | 14 Mar 2024 | 1,067 | 12,763 (0%) | 0% | 2.6 | 2,812 | Common Stock |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 521 | 4,169 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,250 | 6,750 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 521 | 6,434 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2024 | 2,250 | 8,684 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 2.64 per share. | 14 Mar 2024 | 1,012 | 7,672 (0%) | 0% | 2.6 | 2,667 | Common Stock |
| J. Vincent O'Neill | Chief Medical Officer | 14 Dec 2023 | 521 | 4,690 | - | - | Restricted Stock Units | ||
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 521 | 5,913 (0%) | 0% | - | Common Stock | |
| J. O'Neill Vincent | Chief Medical Officer | 14 Dec 2023 | 521 | 2,802 (0%) | 0% | - | Common Stock | ||
| Yocca D. Frank | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 521 | 4,690 | - | - | Restricted Stock Units | |
| Mehta Vimal | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 2,609 | 23,485 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 2,609 | 32,222 (0%) | 0% | - | Common Stock | |
| D. Frank Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 521 | 11,059 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 521 | 4,690 | - | - | Restricted Stock Units | |
| Steinhart Richard I. | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 521 | 3,063 (0%) | 0% | - | Common Stock | |
| Steinhart Richard I. | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Dec 2023 | 521 | 4,690 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 521 | 5,211 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 521 | 2,542 (0%) | 0% | - | Common Stock | |
| Vincent J. O'Neill | Chief Medical Officer | 14 Sep 2023 | 521 | 5,211 | - | - | Restricted Stock Units | ||
| Vincent J. O'Neill | Chief Medical Officer | 14 Sep 2023 | 521 | 2,281 (0%) | 0% | - | Common Stock | ||
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 2,610 | 29,613 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 2,610 | 26,094 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 521 | 5,211 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 521 | 10,538 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 521 | 5,392 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2023 | 521 | 5,211 | - | - | Restricted Stock Units | |
| Peter Mueller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Other type of transaction at price $ 0.00 per share. | 26 Jun 2023 | 17,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Sandeep Laumas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| June Bray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 521 | 5,732 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 521 | 2,021 (0%) | 0% | - | Common Stock | |
| Vincent J. O'Neill | Chief Medical Officer | 14 Jun 2023 | 521 | 1,760 (0%) | 0% | - | Common Stock | ||
| Vincent J. O'Neill | Chief Medical Officer | 14 Jun 2023 | 521 | 5,732 | - | - | Restricted Stock Units | ||
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 21.41 per share. | 14 Jun 2023 | 21,988 | 47,915 (0%) | 0% | 21.4 | 470,763 | Common Stock |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 2,609 | 39,903 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 14 Jun 2023 | 30,000 | 69,903 (0%) | 0% | 0.4 | 12,300 | Common Stock |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 30,000 | 294,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 30,000 | 324,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 2,609 | 28,704 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 21.89 per share. | 14 Jun 2023 | 747 | 39,903 (0%) | 0% | 21.9 | 16,352 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 20.90 per share. | 14 Jun 2023 | 4,266 | 40,650 (0%) | 0% | 20.9 | 89,159 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 20.01 per share. | 14 Jun 2023 | 24,987 | 44,916 (0%) | 0% | 20.0 | 499,990 | Common Stock |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 14 Jun 2023 | 30,000 | 69,903 (0%) | 0% | 0.4 | 12,300 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 21.90 per share. | 14 Jun 2023 | 8,012 | 39,903 (0%) | 0% | 21.9 | 175,463 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 521 | 10,017 (0%) | 0% | - | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 521 | 5,732 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 521 | 5,732 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2023 | 521 | 4,871 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 25.79 per share. | 22 May 2023 | 6,500 | 37,294 (0%) | 0% | 25.8 | 167,641 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 27.17 per share. | 14 May 2023 | 5,000 | 1,500 (0%) | 0% | 27.2 | 135,864 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2023 | 5,000 | 0 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2023 | 5,000 | 6,500 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2023 | 15,000 | 30,894 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2023 | 15,000 | 0 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2023 | 5,000 | 0 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 27.32 per share. | 14 May 2023 | 1,785 | 4,350 (0%) | 0% | 27.3 | 48,765 | Common Stock |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 May 2023 | 5,000 | 6,135 (0%) | 0% | - | Common Stock | |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Apr 2023 | 60,000 | 294,000 | - | - | Stock Options | |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 06 Apr 2023 | 60,000 | 60,000 (0%) | 0% | 0.4 | 24,600 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 17.32 per share. | 06 Apr 2023 | 60,000 | 0 (0%) | 0% | 17.3 | 1,039,200 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 20.15 per share. | 20 Mar 2023 | 900 | 15,894 (0%) | 0% | 20.2 | 18,135 | Common Stock |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Mar 2023 | 30,000 | 354,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Mar 2023 | 30,000 | 384,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 19.70 per share. | 20 Mar 2023 | 29,100 | 16,794 (0%) | 0% | 19.7 | 573,270 | Common Stock |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 20 Mar 2023 | 30,000 | 45,894 (0%) | 0% | 0.4 | 12,300 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 18.88 per share. | 20 Mar 2023 | 604 | 15,894 (0%) | 0% | 18.9 | 11,404 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 18.22 per share. | 20 Mar 2023 | 3,896 | 16,498 (0%) | 0% | 18.2 | 70,985 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 18.86 per share. | 20 Mar 2023 | 5,333 | 20,394 (0%) | 0% | 18.9 | 100,580 | Common Stock |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 20 Mar 2023 | 30,000 | 50,394 (0%) | 0% | 0.4 | 12,300 | Common Stock |
| Vimal Mehta | Director, CEO and President | Sale of securities on an exchange or to another person at price $ 18.20 per share. | 20 Mar 2023 | 24,667 | 25,727 (0%) | 0% | 18.2 | 448,939 | Common Stock |
| Matthew T. Wiley | CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 12,000 | 12,000 | - | - | Restricted Stock Units | |
| Matthew T. Wiley | CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 36,000 | 36,000 | - | - | Stock Option (Right to Buy) | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 9,000 | 9,000 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 6,253 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 19.50 per share. | 14 Mar 2023 | 2,084 | 1,500 (0%) | 0% | 19.5 | 40,638 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 3,584 (0%) | 0% | - | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 32,000 | 32,000 | - | - | Stock Option (Right to Buy) | |
| Vincent J. O'Neill | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 32,000 | 32,000 | - | - | Stock Option (Right to Buy) | |
| Vincent J. O'Neill | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 9,000 | 9,000 | - | - | Restricted Stock Units | |
| Vincent J. O'Neill | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 6,253 | - | - | Restricted Stock Units | |
| Vincent J. O'Neill | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 19.69 per share. | 14 Mar 2023 | 845 | 1,239 (0%) | 0% | 19.7 | 16,642 | Common Stock |
| Vincent J. O'Neill | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 2,084 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 56,000 | 56,000 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 10,437 | 31,313 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 10,437 | 20,394 (0%) | 0% | - | Common Stock | |
| Vimal Mehta | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 168,000 | 168,000 | - | - | Stock Option (Right to Buy) | |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 6,253 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 32,000 | 32,000 | - | - | Stock Option (Right to Buy) | |
| Frank D. Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 9,000 | 9,000 | - | - | Restricted Stock Units | |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.69 per share. | 14 Mar 2023 | 985 | 9,496 (0%) | 0% | 19.7 | 19,396 | Common Stock |
| Frank D. Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 10,481 (0%) | 0% | - | Common Stock | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 32,000 | 32,000 | - | - | Stock Option (Right to Buy) | |
| Javier Rodriguez | See Remarks | Sale of securities on an exchange or to another person at price $ 19.63 per share. | 14 Mar 2023 | 950 | 1,135 (0%) | 0% | 19.6 | 18,644 | Common Stock |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 6,253 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2023 | 9,000 | 9,000 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Mar 2023 | 2,084 | 2,084 (0%) | 0% | - | Common Stock | |
| Vincent J. O'Neill | Chief Medical Officer | 20 Jan 2023 | 29,713 | 29,712 | - | - | Employee Stock Option (right to buy) | ||
| Vincent J. O'Neill | Chief Medical Officer | 20 Jan 2023 | 29,713 | 0 (0%) | 0% | 30 | 891,390 | Common Stock | |
| Vincent J. O'Neill | Chief Medical Officer | 20 Jan 2023 | 29,713 | 29,713 (0%) | 0% | 0.4 | 12,182 | Common Stock | |
| Frank D. Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 20 Jan 2023 | 50,000 | 8,397 (0%) | 0% | 30 | 1,500,000 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 22.93 per share. | 04 Jan 2023 | 800 | 0 (0%) | 0% | 22.9 | 18,344 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2023 | 34,111 | 379,889 | - | - | Stock Options | |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2023 | 25,889 | 354,000 | - | - | Stock Options | |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 22.32 per share. | 04 Jan 2023 | 25,089 | 800 (0%) | 0% | 22.3 | 559,986 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 04 Jan 2023 | 25,889 | 25,889 (0%) | 0% | 0.4 | 10,614 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 22.21 per share. | 04 Jan 2023 | 9,821 | 0 (0%) | 0% | 22.2 | 218,124 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 21.59 per share. | 04 Jan 2023 | 24,290 | 9,821 (0%) | 0% | 21.6 | 524,421 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 04 Jan 2023 | 34,111 | 34,111 (0%) | 0% | 0.4 | 13,986 | Common Stock |
| Vimal Mehta | Director, CEO and President | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 145,549 | 8,546,750 (47%) | 0% | 0 | Common Stock | |
| Krishnan Nandabalan | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 291,097 | 8,546,750 (47%) | 1% | 0 | Common Stock | |
| Krishnan Nandabalan | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 291,097 | 8,546,750 (47%) | 1% | 0 | Common Stock | |
| Krishnan Nandabalan | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 145,549 | 8,546,750 (47%) | 0% | 0 | Common Stock | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 19.21 per share. | 15 Dec 2022 | 20,113 | 19,844 (0%) | 0% | 19.2 | 386,371 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 15 Dec 2022 | 30,000 | 39,957 (0%) | 0% | 0.4 | 12,300 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 20.19 per share. | 15 Dec 2022 | 7,206 | 9,957 (0%) | 0% | 20.2 | 145,489 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 15 Dec 2022 | 30,000 | 39,957 (0%) | 0% | 0.4 | 12,300 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 19.86 per share. | 15 Dec 2022 | 22,794 | 17,163 (0%) | 0% | 19.9 | 452,689 | Common Stock |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2022 | 30,000 | 414,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2022 | 30,000 | 444,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO and President, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 19.92 per share. | 15 Dec 2022 | 9,887 | 9,957 (0%) | 0% | 19.9 | 196,949 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 15.00 per share. | 10 Nov 2022 | 32,550 | 0 (0%) | 0% | 15 | 488,250 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 10 Nov 2022 | 27,450 | 27,450 (0%) | 0% | 0.4 | 11,255 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 15.00 per share. | 10 Nov 2022 | 27,450 | 0 (0%) | 0% | 15 | 411,750 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 10 Nov 2022 | 32,550 | 32,550 (0%) | 0% | 0.4 | 13,346 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Nov 2022 | 27,450 | 446,550 | - | - | Stock Options | |
| Krishnan Nandabalan | Director, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Nov 2022 | 32,550 | 414,000 | - | - | Stock Options | |
| Peter Mueller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Other type of transaction at price $ 0.00 per share. | 19 May 2022 | 17,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Sandeep Laumas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| June Bray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2022 | 17,000 | 17,000 | - | - | Stock Option (Right to Buy) | |
| Richard I. Steinhart | Senior VP and CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2022 | 5,000 | 5,000 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2022 | 15,000 | 15,000 | - | - | Restricted Stock Units | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2022 | 5,000 | 5,000 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 8,337 | 8,337 | - | - | Restricted Stock Units | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 33,350 | 33,350 | - | - | Stock Option (Right to Buy) | |
| Vincent O'Neill | Chief Medical Officer | 14 Mar 2022 | 8,337 | 8,337 | - | - | Restricted Stock Units | ||
| Vimal Mehta | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 41,750 | 41,750 | - | - | Restricted Stock Units | |
| Vimal Mehta | Director, CEO and President | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 167,000 | 167,000 | - | - | Stock Option (Right to Buy) | |
| Frank Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 8,337 | 8,337 | - | - | Restricted Stock Units | |
| Frank Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 33,350 | 33,350 | - | - | Stock Option (Right to Buy) | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 33,350 | 33,350 | - | - | Stock Option (Right to Buy) | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Mar 2022 | 8,337 | 8,337 | - | - | Restricted Stock Units | |
| William P. Kane | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2021 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Aug 2021 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO, President and Secretary | Sale of securities on an exchange or to another person at price $ 30.83 per share. | 25 Jun 2021 | 473,250 | 8,546,750 (47%) | 2% | 30.8 | 14,589,493 | Common Stock |
| Krishnan Nandabalan | Director | Sale of securities on an exchange or to another person at price $ 30.83 per share. | 25 Jun 2021 | 473,250 | 8,546,750 (47%) | 2% | 30.8 | 14,589,493 | Common Stock |
| Peter Mueller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2021 | 14,500 | 14,500 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Other type of transaction at price $ 0.00 per share. | 11 Jun 2021 | 14,500 | 0 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2021 | 14,500 | 14,500 | - | - | Stock Option (Right to Buy) | |
| Sandeep Laumas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2021 | 14,500 | 14,500 | - | - | Stock Option (Right to Buy) | |
| June Bray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2021 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Mar 2021 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Vincent O'Neill | Chief Medical Officer | 25 Mar 2021 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | ||
| Vimal Mehta | Director, CEO, President and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Mar 2021 | 250,000 | 250,000 | - | - | Stock Option (Right to Buy) | |
| Frank Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Mar 2021 | 22,000 | 22,000 | - | - | Stock Option (Right to Buy) | |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 49.30 per share. | 15 Mar 2021 | 630 | 58,397 (0%) | 0% | 49.3 | 31,059 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 48.47 per share. | 15 Mar 2021 | 14,370 | 59,027 (0%) | 0% | 48.5 | 696,514 | Common Stock |
| June Bray | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 4,167 | 4,167 | - | - | Stock Option (Right to Buy) | |
| Javier Rodriguez | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Feb 2021 | 32,000 | 32,000 | - | - | Stock Option (Right to Buy) | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 10,000 | 21,047 | - | - | Employee Stock Option (right to buy) | ||
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 15,000 | 15,000 (0%) | 0% | 0.4 | 6,150 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 10,000 | 25,000 (0%) | 0% | 11 | 110,000 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 2,300 | 22,700 (0%) | 0% | 53.8 | 123,671 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 5,655 | 17,045 (0%) | 0% | 54.5 | 307,915 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 6,872 | 10,173 (0%) | 0% | 55.6 | 381,740 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 9,573 | 600 (0%) | 0% | 56.6 | 541,832 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 600 | 0 (0%) | 0% | 57.2 | 34,302 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 17 Feb 2021 | 15,000 | 59,425 | - | - | Employee Stock Option (right to buy) | ||
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 60.43 per share. | 16 Feb 2021 | 1,772 | 73,997 (0%) | 0% | 60.4 | 107,082 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 61.20 per share. | 16 Feb 2021 | 600 | 73,397 (0%) | 0% | 61.2 | 36,720 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 58.54 per share. | 16 Feb 2021 | 2,886 | 76,269 (0%) | 0% | 58.5 | 168,946 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 57.71 per share. | 16 Feb 2021 | 1,137 | 79,155 (0%) | 0% | 57.7 | 65,616 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 56.49 per share. | 16 Feb 2021 | 6,805 | 80,292 (0%) | 0% | 56.5 | 384,414 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 55.88 per share. | 16 Feb 2021 | 1,300 | 87,097 (0%) | 0% | 55.9 | 72,644 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 59.46 per share. | 16 Feb 2021 | 500 | 75,769 (0%) | 0% | 59.5 | 29,730 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.55 per share. | 01 Feb 2021 | 3,750 | 5,250 (0%) | 0% | 5.6 | 20,813 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2021 | 3,750 | 80,148 | - | - | Stock Option | |
| Richard I. Steinhart | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 48.15 per share. | 01 Feb 2021 | 3,750 | 1,500 (0%) | 0% | 48.2 | 180,563 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jan 2021 | 15,000 | 54,310 | - | - | Employee Stock Option (right to buy) | |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 49.35 per share. | 25 Jan 2021 | 4,107 | 88,397 (0%) | 0% | 49.3 | 202,680 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 47.62 per share. | 25 Jan 2021 | 3,472 | 99,025 (0%) | 0% | 47.6 | 165,337 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 48.39 per share. | 25 Jan 2021 | 6,521 | 92,504 (0%) | 0% | 48.4 | 315,551 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 46.94 per share. | 25 Jan 2021 | 900 | 102,497 (0%) | 0% | 46.9 | 42,246 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 25 Jan 2021 | 15,000 | 103,397 (0%) | 0% | 0.4 | 6,150 | Common Stock |
| Vincent O'Neill | Chief Medical Officer | 19 Jan 2021 | 1,500 | 1,377 (0%) | 0% | 51.5 | 77,175 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 19 Jan 2021 | 12,665 | 5,577 (0%) | 0% | 49.3 | 624,005 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 19 Jan 2021 | 6,758 | 18,242 (0%) | 0% | 48.4 | 327,290 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 19 Jan 2021 | 25,000 | 25,000 (0%) | 0% | 0.4 | 10,250 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 19 Jan 2021 | 25,000 | 74,425 | - | - | Employee Stock Option (right to buy) | ||
| Vincent O'Neill | Chief Medical Officer | 19 Jan 2021 | 1,377 | 0 (0%) | 0% | 52.5 | 72,224 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 19 Jan 2021 | 2,700 | 2,877 (0%) | 0% | 50.4 | 136,026 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 28 Dec 2020 | 3,951 | 1,353 (0%) | 0% | 52.7 | 208,139 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 28 Dec 2020 | 25,000 | 99,425 | - | - | Employee Stock Option (right to buy) | ||
| Vincent O'Neill | Chief Medical Officer | 28 Dec 2020 | 1,353 | 0 (0%) | 0% | 53.5 | 72,440 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 28 Dec 2020 | 25,000 | 25,000 (0%) | 0% | 0.4 | 10,250 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 28 Dec 2020 | 5,727 | 5,304 (0%) | 0% | 51.7 | 296,372 | Common Stock | |
| Vincent O'Neill | Chief Medical Officer | 28 Dec 2020 | 13,969 | 11,031 (0%) | 0% | 50.8 | 709,206 | Common Stock | |
| Reina Benabou | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2020 | 60,000 | 60,000 | - | - | Stock Option (Right to Buy) | |
| William P. Kane | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 110,000 | 110,000 | - | - | Stock Option (Right to Buy) | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2020 | 55,000 | 55,000 | - | - | Employee Stock Option (right to buy) | |
| Vincent O'Neill | Chief Medical Officer | 26 May 2020 | 40,000 | 40,000 | - | - | Employee Stock Option (right to buy) | ||
| Vimal Mehta | Director, CEO, President and Secretary, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2020 | 250,000 | 250,000 | - | - | Employee Stock Option (right to buy) | |
| Frank Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 May 2020 | 45,000 | 45,000 | - | - | Employee Stock Option (right to buy) | |
| Peter Mueller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Peter Mueller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2020 | 5,000 | 5,000 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Other type of transaction at price $ 0.00 per share. | 21 May 2020 | 20,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Sandeep Laumas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2020 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO, President and Secretary, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 30.08 per share. | 24 Feb 2020 | 300,000 | 9,180,000 (50%) | 1% | 30.1 | 9,024,000 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 30.08 per share. | 24 Feb 2020 | 300,000 | 9,180,000 (50%) | 1% | 30.1 | 9,024,000 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2020 | 80,000 | 69,310 | - | - | Stock Option | |
| Frank Yocca | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.41 per share. | 14 Feb 2020 | 80,000 | 88,397 (0%) | 0% | 0.4 | 32,800 | Common Stock |
| Krishnan Nandabalan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2020 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Peter Mueller | None | Purchase of securities on an exchange or from another person at price $ 9.34 per share. | 23 Aug 2019 | 1,554 | 168,320 (0%) | 0% | 9.3 | 14,514 | Common Stock |
| Peter Mueller | None | Purchase of securities on an exchange or from another person at price $ 8.83 per share. | 21 Aug 2019 | 6,646 | 166,766 (0%) | 0% | 8.8 | 58,684 | Common Stock |
| Peter Mueller | None | Purchase of securities on an exchange or from another person at price $ 8.42 per share. | 21 Aug 2019 | 1,800 | 160,120 (0%) | 0% | 8.4 | 15,156 | Common Stock |
| Vimal Mehta | Director, CEO, President and Secretary | Purchase of securities on an exchange or from another person at price $ 8.89 per share. | 16 Aug 2019 | 974 | 9,957 (0%) | 0% | 8.9 | 8,659 | Common Stock |
| Vimal Mehta | Director, CEO, President & Secretary | Purchase of securities on an exchange or from another person at price $ 8.67 per share. | 14 Aug 2019 | 2,625 | 8,983 (0%) | 0% | 8.7 | 22,759 | Common Stock |
| Vimal Mehta | Director, CEO, President & Secretary | Purchase of securities on an exchange or from another person at price $ 8.44 per share. | 14 Aug 2019 | 358 | 6,358 (0%) | 0% | 8.4 | 3,022 | Common Stock |
| Vimal Mehta | Director, CEO, President & Secretary | Purchase of securities on an exchange or from another person at price $ 8.75 per share. | 13 Aug 2019 | 1,000 | 6,000 (0%) | 0% | 8.8 | 8,750 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Purchase of securities on an exchange or from another person at price $ 8.67 per share. | 13 Aug 2019 | 6,547 | 8,397 (0%) | 0% | 8.7 | 56,762 | Common Stock |
| Peter Mueller | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2019 | 14,700 | 14,700 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | None | Other type of transaction at price $ 0.00 per share. | 23 May 2019 | 4,700 | 0 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2019 | 4,700 | 4,700 | - | - | Stock Option (Right to Buy) | |
| Sandeep Laumas | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2019 | 14,700 | 14,700 | - | - | Stock Option (Right to Buy) | |
| Vimal Mehta | Director, CEO, President and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2019 | 187,700 | 187,700 | - | - | Stock Option (Right to Buy) | |
| Michal Votruba | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 07 Mar 2019 | 10,000 | 0 | - | - | Stock Options (Right to Buy) | |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 4.27 per share. | 14 Dec 2018 | 800 | 3,800 (0%) | 0% | 4.3 | 3,416 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 4.50 per share. | 14 Dec 2018 | 100 | 5,000 (0%) | 0% | 4.5 | 450 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 4.49 per share. | 14 Dec 2018 | 400 | 4,900 (0%) | 0% | 4.5 | 1,796 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 4.48 per share. | 14 Dec 2018 | 500 | 4,500 (0%) | 0% | 4.5 | 2,240 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 4.32 per share. | 14 Dec 2018 | 200 | 4,000 (0%) | 0% | 4.3 | 864 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.00 per share. | 06 Dec 2018 | 1,295 | 150,820 (0%) | 0% | 5 | 6,475 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.01 per share. | 06 Dec 2018 | 6,905 | 158,320 (0%) | 0% | 5.0 | 34,594 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.00 per share. | 06 Dec 2018 | 495 | 151,415 (0%) | 0% | 5 | 2,475 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.01 per share. | 06 Dec 2018 | 100 | 150,920 (0%) | 0% | 5.0 | 501 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.12 per share. | 04 Dec 2018 | 344 | 147,263 (0%) | 0% | 5.1 | 1,761 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.09 per share. | 04 Dec 2018 | 1,076 | 146,594 (0%) | 0% | 5.1 | 5,477 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.11 per share. | 04 Dec 2018 | 325 | 146,919 (0%) | 0% | 5.1 | 1,661 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.15 per share. | 04 Dec 2018 | 2,062 | 149,525 (0%) | 0% | 5.1 | 10,619 | Common Stock |
| Peter Mueller | Director | Purchase of securities on an exchange or from another person at price $ 5.13 per share. | 04 Dec 2018 | 200 | 147,463 (0%) | 0% | 5.1 | 1,026 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.15 per share. | 04 Dec 2018 | 500 | 3,000 (0%) | 0% | 5.2 | 2,575 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.09 per share. | 04 Dec 2018 | 500 | 2,500 (0%) | 0% | 5.1 | 2,545 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 5.20 per share. | 03 Dec 2018 | 500 | 1,500 (0%) | 0% | 5.2 | 2,600 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.18 per share. | 03 Dec 2018 | 100 | 1,500 (0%) | 0% | 5.2 | 518 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.13 per share. | 03 Dec 2018 | 100 | 1,300 (0%) | 0% | 5.1 | 513 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.10 per share. | 03 Dec 2018 | 200 | 1,200 (0%) | 0% | 5.1 | 1,020 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.20 per share. | 03 Dec 2018 | 500 | 2,000 (0%) | 0% | 5.2 | 2,600 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.14 per share. | 03 Dec 2018 | 100 | 1,400 (0%) | 0% | 5.1 | 514 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Purchase of securities on an exchange or from another person at price $ 5.23 per share. | 03 Dec 2018 | 450 | 1,400 (0%) | 0% | 5.2 | 2,353 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Purchase of securities on an exchange or from another person at price $ 5.20 per share. | 03 Dec 2018 | 450 | 1,850 (0%) | 0% | 5.2 | 2,339 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 5.00 per share. | 30 Nov 2018 | 500 | 1,000 (0%) | 0% | 5 | 2,500 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.20 per share. | 30 Nov 2018 | 300 | 1,000 (0%) | 0% | 5.2 | 1,560 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.17 per share. | 30 Nov 2018 | 100 | 700 (0%) | 0% | 5.2 | 517 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.05 per share. | 30 Nov 2018 | 300 | 600 (0%) | 0% | 5.1 | 1,515 | Common Stock |
| Vimal Mehta | Director, CEO, President, Secretary | Purchase of securities on an exchange or from another person at price $ 5.04 per share. | 30 Nov 2018 | 300 | 300 (0%) | 0% | 5.0 | 1,512 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Purchase of securities on an exchange or from another person at price $ 5.20 per share. | 30 Nov 2018 | 450 | 950 (0%) | 0% | 5.2 | 2,340 | Common Stock |
| Richard I. Steinhart | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 5.00 per share. | 29 Nov 2018 | 500 | 500 (0%) | 0% | 5 | 2,500 | Common Stock |
| Krishnan Nandabalan | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 4.92 per share. | 29 Nov 2018 | 1,000 | 1,000 (0%) | 0% | 4.9 | 4,915 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Purchase of securities on an exchange or from another person at price $ 5.02 per share. | 29 Nov 2018 | 500 | 500 (0%) | 0% | 5.0 | 2,511 | Common Stock |
| Peter Mueller | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Jul 2018 | 90,000 | 119,795 (0%) | 0% | 0 | Common Stock | |
| Peter Mueller | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Jul 2018 | 90,000 | 90,000 (0%) | 0% | 0 | Common Stock | |
| Richard I. Steinhart | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2018 | 32,232 | 116,130 | - | - | Stock Options | |
| Peter Mueller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2018 | 37,209 | 161,397 | - | - | Stock Options | |
| Vincent O'Neill | Chief Medical Officer | 12 Mar 2018 | 31,047 | 155,472 | - | - | Stock Options | ||
| Sandeep Laumas | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2018 | 37,209 | 124,188 | - | - | Stock Options | |
| Vimal Mehta | Director, CEO, President and Secretary | Other type of transaction at price $ 60.76 per share. | 12 Mar 2018 | 80,000 | 80,000 (0%) | 0% | 60.8 | 4,860,800 | Common Stock |
| Vimal Mehta | Director, CEO, President and Secretary | Purchase of securities on an exchange or from another person at price $ 11.00 per share. | 12 Mar 2018 | 2,000 | 2,000 (0%) | 0% | 11 | 22,000 | Common Stock |
| Vimal Mehta | Director, CEO, President and Secretary | Other type of transaction at price $ 60.76 per share. | 12 Mar 2018 | 160,000 | 9,020,000 (49%) | 0% | 60.8 | 9,721,600 | Common Stock |
| Frank Yocca | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Mar 2018 | 36,498 | 185,808 | - | - | Stock Options |