3.4M XNAS Volume
XNAS 18 Mar, 2025 4:01 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Mar 2025 | 20,834 | 457,500 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.36 per share. | 07 Mar 2025 | 41,668 | 1,635,138 (2%) | 0% | 5.4 | 223,199 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 07 Mar 2025 | 20,834 | 1,676,806 (2%) | 0% | 1.0 | 20,626 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 205,019 | 205,019 | - | - | Stock Option (Right to Buy) | |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 136,680 | 422,648 (0%) | 0% | 0 | Common Stock | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 570,217 | 1,655,972 (2%) | 0% | 0 | Common Stock | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 855,326 | 855,326 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 205,019 | 205,019 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 136,680 | 317,723 (0%) | 0% | 0 | Common Stock | |
| Laura Williams | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 157,700 | 157,700 | - | - | Stock Option (Right to Buy) | |
| Laura Williams | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 105,200 | 409,004 (0%) | 0% | 0 | Common Stock | |
| Eric Duane Foster | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 136,680 | 316,680 (0%) | 0% | 0 | Common Stock | |
| Eric Duane Foster | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 205,019 | 205,019 | - | - | Stock Option (Right to Buy) | |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 5.00 per share. | 24 Feb 2025 | 77,729 | 2,015,494 (3%) | 0% | 5.0 | 388,738 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.62 per share. | 20 Feb 2025 | 5,171 | 285,968 (0%) | 0% | 5.6 | 29,077 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.62 per share. | 20 Feb 2025 | 22,964 | 1,085,755 (1%) | 0% | 5.6 | 129,124 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 5.62 per share. | 20 Feb 2025 | 4,291 | 181,043 (0%) | 0% | 5.6 | 24,128 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.62 per share. | 20 Feb 2025 | 4,941 | 303,804 (0%) | 0% | 5.6 | 27,783 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2025 | 20,833 | 478,334 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.36 per share. | 31 Jan 2025 | 41,666 | 1,108,719 (1%) | 0% | 5.4 | 223,355 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 31 Jan 2025 | 20,833 | 1,150,385 (1%) | 0% | 1.0 | 20,625 | Common Stock |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 4.99 per share. | 21 Jan 2025 | 199,000 | 1,937,765 (2%) | 0% | 5.0 | 992,672 | Common Stock |
| Richard J. Rodgers | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.55 per share. | 16 Jan 2025 | 100,000 | 350,524 (0%) | 0% | 0.6 | 55,000 | Common Stock |
| Richard J. Rodgers | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jan 2025 | 100,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Mott M. David | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.55 per share. | 26 Dec 2024 | 100,000 | 1,738,765 (2%) | 0% | 0.6 | 55,000 | Common Stock |
| David Mott M. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Dec 2024 | 100,000 | 0 | - | - | Stock Option (Right to Buy) | |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 4.67 per share. | 19 Dec 2024 | 213,300 | 1,638,765 (2%) | 0% | 4.7 | 996,580 | Common Stock |
| Raab Michael G. | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.26 per share. | 10 Dec 2024 | 25,000 | 1,150,385 (1%) | 0% | 5.3 | 131,620 | Common Stock |
| Raab Michael G. | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Dec 2024 | 25,000 | 520,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 10 Dec 2024 | 25,000 | 1,175,385 (1%) | 0% | 1.0 | 24,750 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.38 per share. | 25 Nov 2024 | 25,000 | 1,150,385 (1%) | 0% | 5.4 | 134,483 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.79 per share. | 20 Nov 2024 | 5,260 | 291,139 (0%) | 0% | 4.8 | 25,219 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 4.79 per share. | 20 Nov 2024 | 31,980 | 1,175,385 (1%) | 0% | 4.8 | 153,328 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 4.79 per share. | 20 Nov 2024 | 4,941 | 297,005 (0%) | 0% | 4.8 | 23,690 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 4.79 per share. | 20 Nov 2024 | 2,243 | 151,373 (0%) | 0% | 4.8 | 10,754 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 4.79 per share. | 20 Nov 2024 | 7,046 | 185,334 (0%) | 0% | 4.8 | 33,782 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 4.79 per share. | 20 Nov 2024 | 4,941 | 314,421 (0%) | 0% | 4.8 | 23,690 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 4.79 per share. | 20 Nov 2024 | 7,366 | 308,745 (0%) | 0% | 4.8 | 35,316 | Common Stock |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 4.62 per share. | 13 Nov 2024 | 215,868 | 1,425,465 (2%) | 0% | 4.6 | 996,598 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 4.90 per share. | 11 Nov 2024 | 2,743 | 1,207,365 (1%) | 0% | 4.9 | 13,441 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.32 per share. | 06 Nov 2024 | 27,171 | 180,787 (0%) | 0% | 2.3 | 63,037 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Nov 2024 | 27,171 | 0 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.10 per share. | 06 Nov 2024 | 27,171 | 153,616 (0%) | 0% | 6.1 | 165,743 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.32 per share. | 04 Nov 2024 | 27,172 | 180,788 (0%) | 0% | 2.3 | 63,039 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Nov 2024 | 27,172 | 27,171 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.95 per share. | 04 Nov 2024 | 27,172 | 153,616 (0%) | 0% | 5.9 | 161,673 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 28 Oct 2024 | 25,000 | 1,235,108 (1%) | 0% | 1.0 | 24,750 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Oct 2024 | 25,000 | 545,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.91 per share. | 28 Oct 2024 | 25,000 | 1,210,108 (1%) | 0% | 5.9 | 147,740 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.01 per share. | 11 Oct 2024 | 7,500 | 1,210,108 (1%) | 0% | 6.0 | 45,075 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.92 per share. | 27 Sep 2024 | 49,564 | 301,946 (0%) | 0% | 6.9 | 342,983 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.07 per share. | 26 Sep 2024 | 3,000 | 1,217,608 (1%) | 0% | 6.1 | 18,210 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.26 per share. | 13 Sep 2024 | 5,312 | 153,616 (0%) | 0% | 6.3 | 33,254 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 11 Sep 2024 | 35,000 | 1,255,608 (1%) | 0% | 1.0 | 34,650 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Sep 2024 | 35,000 | 570,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.61 per share. | 11 Sep 2024 | 35,000 | 1,220,608 (1%) | 0% | 5.6 | 196,399 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.22 per share. | 27 Aug 2024 | 7,500 | 1,219,509 (1%) | 0% | 6.2 | 46,635 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 5,289 | 295,257 (0%) | 0% | 5.9 | 30,995 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 32,225 | 1,227,009 (1%) | 0% | 5.9 | 188,848 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 2,250 | 156,252 (0%) | 0% | 5.9 | 13,186 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 4,969 | 351,510 (0%) | 0% | 5.9 | 29,120 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 7,089 | 192,380 (0%) | 0% | 5.9 | 41,544 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 4,969 | 319,362 (0%) | 0% | 5.9 | 29,120 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 7,412 | 314,740 (0%) | 0% | 5.9 | 43,437 | Common Stock |
| Robert Felsch | See Remarks | Sale of securities on an exchange or to another person at price $ 5.86 per share. | 20 Aug 2024 | 3,567 | 91,560 (0%) | 0% | 5.9 | 20,904 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.00 per share. | 16 Aug 2024 | 20,507 | 158,502 (0%) | 0% | 6 | 123,042 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 16 Aug 2024 | 20,507 | 179,009 (0%) | 0% | 1.0 | 20,302 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.94 per share. | 16 Aug 2024 | 20,000 | 356,479 (0%) | 0% | 5.9 | 118,740 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Aug 2024 | 20,507 | 49,806 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.71 per share. | 12 Aug 2024 | 1,229 | 1,259,234 (1%) | 0% | 5.7 | 7,018 | Common Stock |
| Eric Duane Foster | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2024 | 230,000 | 230,000 | - | - | Stock Option (Right to Buy) | |
| Eric Duane Foster | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Aug 2024 | 180,000 | 180,000 (0%) | 0% | 0 | Common Stock | |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 29 Jul 2024 | 30,000 | 1,290,463 (1%) | 0% | 1.0 | 29,700 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Jul 2024 | 30,000 | 605,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.64 per share. | 29 Jul 2024 | 30,000 | 1,260,463 (1%) | 0% | 5.6 | 169,314 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.97 per share. | 15 Jul 2024 | 7,500 | 1,260,463 (1%) | 0% | 6.0 | 44,768 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.59 per share. | 28 Jun 2024 | 2,310 | 1,267,963 (1%) | 0% | 6.6 | 15,223 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 5.96 per share. | 21 Jun 2024 | 38,000 | 324,331 (0%) | 0% | 6.0 | 226,290 | Common Stock |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 40,243 | 40,243 | - | - | Stock Option (Right to Buy) | |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 12,204 | 250,524 (0%) | 0% | 0 | Common Stock | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 11,023 | 229,766 (0%) | 0% | 0 | Common Stock | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 40,243 | 40,243 | - | - | Stock Option (Right to Buy) | |
| David M. Mott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 17,322 | 1,209,597 (1%) | 0% | 0 | Common Stock | |
| David M. Mott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 40,243 | 40,243 | - | - | Stock Option (Right to Buy) | |
| Robert B. Bazemore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 40,243 | 40,243 | - | - | Stock Option (Right to Buy) | |
| Onaiza Cadoret-Manier | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 40,243 | 40,243 | - | - | Stock Option (Right to Buy) | |
| Muna Bhanji | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 40,243 | 40,243 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.65 per share. | 13 Jun 2024 | 35,000 | 1,270,273 (1%) | 0% | 6.6 | 232,743 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Jun 2024 | 35,000 | 665,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 13 Jun 2024 | 35,000 | 1,305,273 (1%) | 0% | 1.0 | 34,650 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.12 per share. | 05 Jun 2024 | 45,000 | 422,152 (0%) | 0% | 7.1 | 320,580 | Common Stock |
| Laura Williams | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2024 | 100,000 | 251,000 | - | - | Stock Option (Right to Buy) | |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.12 per share. | 05 Jun 2024 | 100,000 | 322,152 (0%) | 0% | 7.1 | 712,500 | Common Stock |
| Laura Williams | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.75 per share. | 05 Jun 2024 | 100,000 | 467,152 (0%) | 0% | 2.8 | 275,000 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 7.00 per share. | 03 Jun 2024 | 17,872 | 158,502 (0%) | 0% | 7 | 125,104 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.72 per share. | 29 May 2024 | 7,500 | 1,270,273 (1%) | 0% | 6.7 | 50,390 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 5,167 | 300,546 (0%) | 0% | 7.8 | 40,359 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 31,484 | 1,277,773 (1%) | 0% | 7.8 | 245,922 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 4,855 | 376,479 (0%) | 0% | 7.8 | 37,922 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 2,198 | 176,374 (0%) | 0% | 7.8 | 17,169 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 6,927 | 199,469 (0%) | 0% | 7.8 | 54,107 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 6,703 | 449,092 (0%) | 0% | 7.8 | 52,357 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 4,855 | 362,331 (0%) | 0% | 7.8 | 37,922 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 4,794 | 367,152 (0%) | 0% | 7.8 | 37,446 | Common Stock |
| Robert Felsch | See Remarks | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 21 May 2024 | 3,485 | 95,127 (0%) | 0% | 7.8 | 27,221 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 7.99 per share. | 14 May 2024 | 3,000 | 1,307,933 (1%) | 0% | 8.0 | 23,970 | Common Stock |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 06 May 2024 | 110,250 | 378,243 (0%) | 0% | 1.0 | 109,148 | Common Stock |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2024 | 109,687 | 241,313 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2024 | 110,250 | 85,750 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 8.88 per share. | 06 May 2024 | 219,937 | 203,760 (0%) | 0% | 8.9 | 1,952,381 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 8.87 per share. | 06 May 2024 | 64,233 | 423,697 (0%) | 0% | 8.9 | 569,837 | Common Stock |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.75 per share. | 06 May 2024 | 109,687 | 487,930 (0%) | 0% | 2.7 | 301,639 | Common Stock |
| Robert Felsch | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.84 per share. | 06 May 2024 | 79,101 | 263,935 (0%) | 0% | 0.8 | 66,445 | Common Stock |
| Robert Felsch | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2024 | 40,000 | 80,000 | - | - | Stock Option (Right to Buy) | |
| Robert Felsch | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2024 | 79,101 | 61,525 | - | - | Stock Option (Right to Buy) | |
| Robert Felsch | See Remarks | Sale of securities on an exchange or to another person at price $ 8.80 per share. | 06 May 2024 | 55,000 | 95,947 (0%) | 0% | 8.8 | 484,000 | Common Stock |
| Robert Felsch | See Remarks | Sale of securities on an exchange or to another person at price $ 8.81 per share. | 06 May 2024 | 152,988 | 150,947 (0%) | 0% | 8.8 | 1,347,503 | Common Stock |
| Robert Felsch | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.75 per share. | 06 May 2024 | 40,000 | 303,935 (0%) | 0% | 2.8 | 110,000 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 9.00 per share. | 03 May 2024 | 45,000 | 267,993 (0%) | 0% | 9 | 405,000 | Common Stock |
| Laura Williams | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 May 2024 | 30,000 | 162,000 | - | - | Stock Option (Right to Buy) | |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 8.35 per share. | 03 May 2024 | 39,949 | 370,189 (0%) | 0% | 8.3 | 333,574 | Common Stock |
| Laura Williams | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 03 May 2024 | 30,000 | 410,138 (0%) | 0% | 1.0 | 29,700 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 29 Apr 2024 | 30,000 | 1,340,933 (2%) | 0% | 1.0 | 29,700 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Apr 2024 | 30,000 | 670,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.40 per share. | 29 Apr 2024 | 30,000 | 1,310,933 (1%) | 0% | 6.4 | 192,057 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 7.06 per share. | 15 Apr 2024 | 7,500 | 1,310,933 (1%) | 0% | 7.1 | 52,924 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 7.31 per share. | 01 Apr 2024 | 1,518 | 1,318,433 (2%) | 0% | 7.3 | 11,097 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 7.73 per share. | 20 Mar 2024 | 86,000 | 312,993 (0%) | 0% | 7.7 | 664,978 | Common Stock |
| Robert Blanks | See Remarks | Gift of securities by or to the insider at price $ 0.00 per share. | 15 Mar 2024 | 1,000 | 367,186 (0%) | 0% | 0 | Common Stock | |
| P. David Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 9.20 per share. | 26 Feb 2024 | 5,183 | 175,936 (0%) | 0% | 9.2 | 47,684 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 4,803 | 380,138 (0%) | 0% | 8.7 | 42,008 | Common Stock |
| Blanks Robert | See Remarks | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 5,017 | 368,186 (0%) | 0% | 8.7 | 43,880 | Common Stock |
| P. David Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 5,017 | 378,985 (0%) | 0% | 8.7 | 43,880 | Common Stock |
| A. Justin Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 5,341 | 304,835 (0%) | 0% | 8.7 | 46,714 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 2,294 | 181,119 (0%) | 0% | 8.7 | 20,064 | Common Stock |
| Felsch Robert | See Remarks | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 2,352 | 184,834 (0%) | 0% | 8.7 | 20,571 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 4,432 | 398,993 (0%) | 0% | 8.7 | 38,764 | Common Stock |
| Michael Raab G. | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 22,917 | 1,319,951 (2%) | 0% | 8.7 | 200,439 | Common Stock |
| Rodriguez Susan | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 20 Feb 2024 | 6,928 | 452,795 (0%) | 0% | 8.7 | 60,594 | Common Stock |
| Rosenbaum David P. | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 9.18 per share. | 08 Feb 2024 | 15,344 | 384,002 (0%) | 0% | 9.2 | 140,846 | Common Stock |
| Williams Laura | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 152,127 | 152,127 | - | - | Stock Option (Right to Buy) | |
| Susan Rodriguez | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 112,750 | 459,723 (0%) | 0% | 0 | Common Stock | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 112,750 | 373,203 (0%) | 0% | 0 | Common Stock | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 475,000 | 1,342,868 (2%) | 0% | 0 | Common Stock | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 164,000 | 164,000 | - | - | Stock Option (Right to Buy) | |
| Rodriguez Susan | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 145,000 | 145,000 | - | - | Stock Option (Right to Buy) | |
| A. Renz Justin | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 127,750 | 310,176 (0%) | 0% | 0 | Common Stock | |
| Laura Williams | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 118,750 | 384,941 (0%) | 0% | 0 | Common Stock | |
| Rosenbaum P. David | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 70,120 | 183,413 (0%) | 0% | 0 | Common Stock | |
| Felsch Robert | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 70,120 | 187,186 (0%) | 0% | 0 | Common Stock | |
| Michael Raab G. | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 605,904 | 605,904 | - | - | Stock Option (Right to Buy) | |
| Felsch Robert | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 99,000 | 99,000 | - | - | Stock Option (Right to Buy) | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 145,000 | 145,000 | - | - | Stock Option (Right to Buy) | |
| Grammer Elizabeth | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 127,750 | 403,425 (0%) | 0% | 0 | Common Stock | |
| A. Justin Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 164,000 | 164,000 | - | - | Stock Option (Right to Buy) | |
| P. David Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 145,000 | 145,000 | - | - | Stock Option (Right to Buy) | |
| Rosenbaum P. David | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 112,750 | 399,346 (0%) | 0% | 0 | Common Stock | |
| P. David Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 99,000 | 99,000 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.64 per share. | 08 Jan 2024 | 30,000 | 286,596 (0%) | 0% | 6.6 | 199,200 | Common Stock |
| A. Justin Renz | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Dec 2023 | 75,000 | 121,000 | - | - | Stock Option (Right to Buy) | |
| Renz A. Justin | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.36 per share. | 26 Dec 2023 | 225,000 | 182,426 (0%) | 0% | 6.4 | 1,430,123 | Common Stock |
| A. Renz Justin | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.99 per share. | 26 Dec 2023 | 75,000 | 407,426 (0%) | 0% | 1.0 | 74,250 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.07 per share. | 18 Dec 2023 | 5,675 | 316,596 (0%) | 0% | 6.1 | 34,447 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.55 per share. | 14 Dec 2023 | 7,000 | 322,271 (0%) | 0% | 5.6 | 38,850 | Common Stock |
| Grammer Elizabeth | See Remarks | Sale of securities on an exchange or to another person at price $ 5.08 per share. | 11 Dec 2023 | 50,000 | 275,675 (0%) | 0% | 5.1 | 253,925 | Common Stock |
| David Rosenbaum P. | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.27 per share. | 08 Dec 2023 | 20,000 | 329,271 (0%) | 0% | 5.3 | 105,476 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 2,884 | 333,849 (0%) | 0% | 3.6 | 10,243 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 11,419 | 876,236 (1%) | 0% | 3.6 | 40,558 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 2,846 | 369,919 (0%) | 0% | 3.6 | 10,108 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 937 | 111,225 (0%) | 0% | 3.6 | 3,328 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 2,392 | 328,059 (0%) | 0% | 3.6 | 8,496 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 4,733 | 348,687 (0%) | 0% | 3.6 | 16,811 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 2,846 | 263,288 (0%) | 0% | 3.6 | 10,108 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 2,591 | 291,839 (0%) | 0% | 3.6 | 9,203 | Common Stock |
| Robert Felsch | See Remarks | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 21 Aug 2023 | 1,048 | 115,110 (0%) | 0% | 3.6 | 3,722 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 3.35 per share. | 27 Jun 2023 | 25,000 | 294,430 (0%) | 0% | 3.3 | 83,633 | Common Stock |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 18,494 | 238,320 (0%) | 0% | 0 | Common Stock | |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 16,581 | 218,743 (0%) | 0% | 0 | Common Stock | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| David M. Mott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| David M. Mott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 25,510 | 1,192,275 (1%) | 0% | 0 | Common Stock | |
| Jan M. Lundberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 12,755 | 146,794 (0%) | 0% | 0 | Common Stock | |
| Jan M. Lundberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| Robert B. Bazemore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| Geoffrey A. Block | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| Onaiza Cadoret-Manier | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 12,755 | 110,150 (0%) | 0% | 0 | Common Stock | |
| Onaiza Cadoret-Manier | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| Muna Bhanji | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2023 | 49,237 | 49,237 | - | - | Stock Option (Right to Buy) | |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 2,873 | 336,733 (0%) | 0% | 3.7 | 10,496 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 11,357 | 887,655 (1%) | 0% | 3.7 | 41,489 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 934 | 112,162 (0%) | 0% | 3.7 | 3,412 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 2,835 | 372,765 (0%) | 0% | 3.7 | 10,357 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 2,384 | 330,451 (0%) | 0% | 3.7 | 8,709 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 4,711 | 353,420 (0%) | 0% | 3.7 | 17,210 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 2,835 | 266,134 (0%) | 0% | 3.7 | 10,357 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 2,583 | 319,430 (0%) | 0% | 3.7 | 9,436 | Common Stock |
| Robert Felsch | See Remarks | Sale of securities on an exchange or to another person at price $ 3.65 per share. | 23 May 2023 | 1,046 | 116,158 (0%) | 0% | 3.7 | 3,821 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 4.63 per share. | 29 Mar 2023 | 3,000 | 113,096 (0%) | 0% | 4.6 | 13,888 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 3,439 | 336,606 (0%) | 0% | 3.0 | 10,320 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 13,449 | 896,012 (1%) | 0% | 3.0 | 40,360 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 3,394 | 375,600 (0%) | 0% | 3.0 | 10,185 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 1,114 | 113,096 (0%) | 0% | 3.0 | 3,343 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 2,914 | 329,954 (0%) | 0% | 3.0 | 8,745 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 5,586 | 355,131 (0%) | 0% | 3.0 | 16,764 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 3,394 | 268,969 (0%) | 0% | 3.0 | 10,185 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 3,187 | 319,013 (0%) | 0% | 3.0 | 9,564 | Common Stock |
| Robert Felsch | See Remarks | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 21 Feb 2023 | 3,214 | 114,204 (0%) | 0% | 3.0 | 9,645 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 78,000 | 340,045 (0%) | 0% | 0 | Common Stock | |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 351,000 | 351,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 1,124,000 | 1,124,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 250,000 | 909,461 (1%) | 0% | 0 | Common Stock | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 25,325 | 114,210 (0%) | 0% | 0 | Common Stock | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 78,000 | 378,994 (0%) | 0% | 0 | Common Stock | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 116,250 | 116,250 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 351,000 | 351,000 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 351,000 | 351,000 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 78,000 | 332,868 (0%) | 0% | 0 | Common Stock | |
| Susan Rodriguez | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 351,000 | 351,000 | - | - | Stock Option (Right to Buy) | |
| Susan Rodriguez | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 78,000 | 360,717 (0%) | 0% | 0 | Common Stock | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 78,000 | 272,363 (0%) | 0% | 0 | Common Stock | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 351,000 | 351,000 | - | - | Stock Option (Right to Buy) | |
| Laura Williams | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 351,000 | 351,000 | - | - | Stock Option (Right to Buy) | |
| Laura Williams | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 78,000 | 322,200 (0%) | 0% | 0 | Common Stock | |
| Robert Felsch | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 26,000 | 117,418 (0%) | 0% | 0 | Common Stock | |
| Robert Felsch | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2023 | 120,000 | 120,000 | - | - | Stock Option (Right to Buy) | |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 1,443 | 262,045 (0%) | 0% | 1.9 | 2,813 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.93 per share. | 22 Nov 2022 | 61 | 263,488 (0%) | 0% | 1.9 | 118 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 22 Nov 2022 | 162 | 665,518 (1%) | 0% | 1.9 | 314 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 5,936 | 659,461 (1%) | 0% | 1.9 | 11,571 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 22 Nov 2022 | 121 | 665,397 (1%) | 0% | 1.9 | 235 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 2.00 per share. | 22 Nov 2022 | 2 | 89,356 (0%) | 0% | 2 | 4 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.91 per share. | 22 Nov 2022 | 11 | 89,358 (0%) | 0% | 1.9 | 21 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 1,405 | 300,994 (0%) | 0% | 1.9 | 2,739 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 22 Nov 2022 | 33 | 302,399 (0%) | 0% | 1.9 | 64 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.92 per share. | 22 Nov 2022 | 26 | 302,432 (0%) | 0% | 1.9 | 50 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 471 | 88,885 (0%) | 0% | 1.9 | 918 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 1,193 | 254,868 (0%) | 0% | 1.9 | 2,326 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 1.93 per share. | 22 Nov 2022 | 29 | 256,081 (0%) | 0% | 1.9 | 56 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 20 | 256,061 (0%) | 0% | 2.0 | 39 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 22 Nov 2022 | 131 | 286,042 (0%) | 0% | 1.9 | 254 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 3,303 | 282,717 (0%) | 0% | 1.9 | 6,439 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 22 | 286,020 (0%) | 0% | 2.0 | 43 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 1,405 | 194,363 (0%) | 0% | 1.9 | 2,739 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 1.92 per share. | 22 Nov 2022 | 26 | 195,768 (0%) | 0% | 1.9 | 50 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 22 Nov 2022 | 33 | 195,794 (0%) | 0% | 1.9 | 64 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.93 per share. | 22 Nov 2022 | 15 | 245,426 (0%) | 0% | 1.9 | 29 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 22 Nov 2022 | 33 | 245,393 (0%) | 0% | 1.9 | 64 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 22 Nov 2022 | 1,193 | 244,200 (0%) | 0% | 1.9 | 2,326 | Common Stock |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 1.76 per share. | 17 Nov 2022 | 567,000 | 1,166,765 (1%) | 0% | 1.8 | 1,000,642 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 1.50 per share. | 05 Oct 2022 | 100,000 | 195,827 (0%) | 0% | 1.5 | 150,000 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.62 per share. | 31 Aug 2022 | 3,000 | 263,549 (0%) | 0% | 0.6 | 1,856 | Common Stock |
| Michael G. Raab | Director, President & CEO | Purchase of securities on an exchange or from another person at price $ 0.62 per share. | 31 Aug 2022 | 3,000 | 665,680 (1%) | 0% | 0.6 | 1,856 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.92 per share. | 31 Aug 2022 | 3,000 | 89,369 (0%) | 0% | 0.9 | 2,760 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Purchase of securities on an exchange or from another person at price $ 0.62 per share. | 31 Aug 2022 | 3,000 | 92,369 (0%) | 0% | 0.6 | 1,856 | Common Stock |
| Elizabeth Grammer | See Remarks | Purchase of securities on an exchange or from another person at price $ 0.62 per share. | 31 Aug 2022 | 3,000 | 256,110 (0%) | 0% | 0.6 | 1,856 | Common Stock |
| Laura Williams | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.62 per share. | 31 Aug 2022 | 3,000 | 245,441 (0%) | 0% | 0.6 | 1,856 | Common Stock |
| Robert Felsch | See Remarks | Purchase of securities on an exchange or from another person at price $ 0.62 per share. | 31 Aug 2022 | 3,000 | 91,418 (0%) | 0% | 0.6 | 1,856 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 1.04 per share. | 26 Aug 2022 | 21,842 | 295,827 (0%) | 0% | 1.0 | 22,713 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 6 | 260,561 (0%) | 0% | 1 | 6 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 12 | 260,549 (0%) | 0% | 1 | 12 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 1,480 | 260,567 (0%) | 0% | 1.0 | 1,456 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 54 | 662,756 (1%) | 0% | 1.0 | 53 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 6,016 | 662,810 (1%) | 0% | 1.0 | 5,918 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.97 per share. | 22 Aug 2022 | 76 | 662,680 (1%) | 0% | 1.0 | 74 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 1 | 89,369 (0%) | 0% | 1 | 1 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 496 | 89,370 (0%) | 0% | 1.0 | 488 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 17 | 302,458 (0%) | 0% | 1 | 17 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 1,441 | 302,475 (0%) | 0% | 1.0 | 1,418 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 9 | 253,110 (0%) | 0% | 1 | 9 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 2 | 253,119 (0%) | 0% | 1 | 2 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 1,225 | 253,121 (0%) | 0% | 1.0 | 1,205 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 64 | 286,173 (0%) | 0% | 1.0 | 63 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 3,356 | 286,237 (0%) | 0% | 1.0 | 3,301 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 1,441 | 317,686 (0%) | 0% | 1.0 | 1,418 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 17 | 317,669 (0%) | 0% | 1 | 17 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Aug 2022 | 1,263 | 242,454 (0%) | 0% | 1.0 | 1,242 | Common Stock |
| Laura Williams | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.00 per share. | 22 Aug 2022 | 13 | 242,441 (0%) | 0% | 1 | 13 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 26 Jul 2022 | 5,188 | 319,127 (0%) | 0% | 0.7 | 3,476 | Common Stock |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 132,299 | 219,826 (0%) | 0% | 0 | Common Stock | |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 118,613 | 202,162 (0%) | 0% | 0 | Common Stock | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| David M. Mott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 182,481 | 599,765 (0%) | 0% | 0 | Common Stock | |
| David M. Mott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Jan M. Lundberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 91,240 | 134,039 (0%) | 0% | 0 | Common Stock | |
| Jan M. Lundberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Robert B. Bazemore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Geoffrey A. Block | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Onaiza Cadoret-Manier | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 91,240 | 97,395 (0%) | 0% | 0 | Common Stock | |
| Onaiza Cadoret-Manier | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Muna Bhanji | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Muna Bhanji | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 95,802 | 95,802 (0%) | 0% | 0 | Common Stock | |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.64 per share. | 06 Jun 2022 | 1,518 | 262,047 (0%) | 0% | 0.6 | 965 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 06 Jun 2022 | 71,794 | 263,565 (0%) | 0% | 0.7 | 46,731 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.64 per share. | 06 Jun 2022 | 2,144 | 668,826 (1%) | 0% | 0.6 | 1,363 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 06 Jun 2022 | 101,480 | 670,970 (1%) | 0% | 0.7 | 66,053 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.64 per share. | 06 Jun 2022 | 366 | 89,866 (0%) | 0% | 0.6 | 233 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 06 Jun 2022 | 43,093 | 304,827 (0%) | 0% | 0.7 | 28,049 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.64 per share. | 06 Jun 2022 | 911 | 303,916 (0%) | 0% | 0.6 | 579 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 06 Jun 2022 | 17,270 | 90,232 (0%) | 0% | 0.7 | 11,241 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 0.64 per share. | 06 Jun 2022 | 1,260 | 254,346 (0%) | 0% | 0.6 | 801 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 06 Jun 2022 | 59,561 | 255,606 (0%) | 0% | 0.7 | 38,768 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 06 Jun 2022 | 43,010 | 290,503 (0%) | 0% | 0.7 | 27,995 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.64 per share. | 06 Jun 2022 | 910 | 289,593 (0%) | 0% | 0.6 | 578 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 0.64 per share. | 06 Jun 2022 | 1,517 | 324,315 (0%) | 0% | 0.6 | 964 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 0.65 per share. | 06 Jun 2022 | 71,795 | 325,832 (0%) | 0% | 0.7 | 46,731 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 20 May 2022 | 1,528 | 335,359 (0%) | 0% | 0.7 | 1,026 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 20 May 2022 | 6,124 | 772,450 (1%) | 0% | 0.7 | 4,112 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 20 May 2022 | 1,489 | 347,920 (0%) | 0% | 0.7 | 1,000 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 20 May 2022 | 524 | 107,502 (0%) | 0% | 0.7 | 352 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 20 May 2022 | 1,263 | 315,167 (0%) | 0% | 0.7 | 848 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 20 May 2022 | 3,425 | 333,513 (0%) | 0% | 0.7 | 2,300 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 20 May 2022 | 1,489 | 397,627 (0%) | 0% | 0.7 | 1,000 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 22 Feb 2022 | 1,800 | 333,887 (0%) | 0% | 0.7 | 1,206 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 22 Feb 2022 | 6,229 | 775,574 (1%) | 0% | 0.7 | 4,173 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 22 Feb 2022 | 1,752 | 349,409 (0%) | 0% | 0.7 | 1,174 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 22 Feb 2022 | 601 | 105,026 (0%) | 0% | 0.7 | 403 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 22 Feb 2022 | 3,400 | 333,938 (0%) | 0% | 0.7 | 2,278 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 22 Feb 2022 | 1,752 | 399,116 (0%) | 0% | 0.7 | 1,174 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 42,000 | 335,687 (0%) | 0% | 0 | Common Stock | |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 196,000 | 196,000 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 150,000 | 781,803 (1%) | 0% | 0 | Common Stock | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 700,000 | 700,000 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 70,313 | 70,313 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 190,000 | 190,000 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 15,000 | 105,627 (0%) | 0% | 0 | Common Stock | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 40,000 | 351,161 (0%) | 0% | 0 | Common Stock | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 196,000 | 196,000 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 42,000 | 317,958 (0%) | 0% | 0 | Common Stock | |
| Susan Rodriguez | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 195,000 | 195,000 | - | - | Stock Option (Right to Buy) | |
| Susan Rodriguez | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 141,000 | 338,031 (0%) | 0% | 0 | Common Stock | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 190,000 | 190,000 | - | - | Stock Option (Right to Buy) | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2022 | 40,000 | 400,868 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.51 per share. | 09 Dec 2021 | 397,124 | 7,689,277 (11%) | 0% | 1.5 | 600,809 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.14 per share. | 09 Dec 2021 | 323,167 | 2,258,850 (3%) | 0% | 1.1 | 369,412 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.14 per share. | 09 Dec 2021 | 888,185 | 6,207,480 (9%) | 1% | 1.1 | 1,015,284 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.24 per share. | 09 Dec 2021 | 216,049 | 2,582,017 (3%) | 0% | 1.2 | 268,787 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.24 per share. | 09 Dec 2021 | 191,074 | 2,285,682 (3%) | 0% | 1.2 | 237,715 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.24 per share. | 09 Dec 2021 | 593,612 | 7,095,665 (10%) | 0% | 1.2 | 738,513 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.51 per share. | 09 Dec 2021 | 144,533 | 2,798,066 (4%) | 0% | 1.5 | 218,664 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.51 per share. | 09 Dec 2021 | 127,826 | 2,476,756 (3%) | 0% | 1.5 | 193,388 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.51 per share. | 09 Dec 2021 | 127,826 | 2,476,756 (3%) | 0% | 1.5 | 193,388 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.14 per share. | 09 Dec 2021 | 323,167 | 2,258,850 (3%) | 0% | 1.1 | 369,412 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.14 per share. | 09 Dec 2021 | 888,185 | 6,207,480 (9%) | 1% | 1.1 | 1,015,284 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.24 per share. | 09 Dec 2021 | 216,049 | 2,582,017 (3%) | 0% | 1.2 | 268,787 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.24 per share. | 09 Dec 2021 | 191,074 | 2,285,682 (3%) | 0% | 1.2 | 237,715 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.24 per share. | 09 Dec 2021 | 593,612 | 7,095,665 (10%) | 0% | 1.2 | 738,513 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.51 per share. | 09 Dec 2021 | 144,533 | 2,798,066 (4%) | 0% | 1.5 | 218,664 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.51 per share. | 09 Dec 2021 | 397,124 | 7,689,277 (11%) | 0% | 1.5 | 600,809 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 643 | 293,687 (0%) | 0% | 1.0 | 638 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 2,607 | 631,803 (0%) | 0% | 1.0 | 2,586 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 184 | 90,627 (0%) | 0% | 1.0 | 182 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 643 | 311,161 (0%) | 0% | 1.0 | 638 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 754 | 119,483 (0%) | 0% | 1.0 | 748 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.98 per share. | 22 Nov 2021 | 5,000 | 120,237 (0%) | 0% | 1.0 | 4,882 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 537 | 275,958 (0%) | 0% | 1.0 | 533 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 643 | 197,030 (0%) | 0% | 1.0 | 638 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 0.99 per share. | 22 Nov 2021 | 643 | 360,868 (0%) | 0% | 1.0 | 638 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.13 per share. | 15 Nov 2021 | 5,000 | 125,237 (0%) | 0% | 1.1 | 5,650 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.18 per share. | 08 Nov 2021 | 2,166 | 130,237 (0%) | 0% | 1.2 | 2,556 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 631 | 40,047 (0%) | 0% | 1.3 | 833 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 2,573 | 329,730 (0%) | 0% | 1.3 | 3,396 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 176 | 26,574 (0%) | 0% | 1.3 | 232 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 631 | 158,804 (0%) | 0% | 1.3 | 833 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 741 | 127,697 (0%) | 0% | 1.3 | 978 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 526 | 102,386 (0%) | 0% | 1.3 | 694 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 630 | 44,673 (0%) | 0% | 1.3 | 832 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 1.32 per share. | 20 Aug 2021 | 631 | 106,323 (0%) | 0% | 1.3 | 833 | Common Stock |
| Michael G. Raab | Director, President & CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.64 per share. | 03 Aug 2021 | 150,343 | 332,303 (0%) | 0% | 1.6 | 246,563 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.54 per share. | 03 Aug 2021 | 267,892 | 482,646 (0%) | 0% | 0.5 | 144,662 | Common Stock |
| Michael G. Raab | Director, President & CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Aug 2021 | 267,892 | 0 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jacobs | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Aug 2021 | 10,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jacobs | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.64 per share. | 03 Aug 2021 | 5,613 | 128,438 (0%) | 0% | 1.6 | 9,205 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.54 per share. | 03 Aug 2021 | 10,000 | 134,051 (0%) | 0% | 0.5 | 5,400 | Common Stock |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 9,917 | 87,527 (0%) | 0% | 0 | Common Stock | |
| Richard J. Rodgers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 32,765 | 32,765 | - | - | Stock Option (Right to Buy) | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 8,891 | 83,549 (0%) | 0% | 0 | Common Stock | |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 32,765 | 32,765 | - | - | Stock Option (Right to Buy) | |
| David M. Mott | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 32,765 | 32,765 | - | - | Stock Option (Right to Buy) | |
| Jan M. Lundberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 32,765 | 32,765 | - | - | Stock Option (Right to Buy) | |
| Jan M. Lundberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 7,181 | 42,799 (0%) | 0% | 0 | Common Stock | |
| Robert B. Bazemore | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 32,765 | 32,765 | - | - | Stock Option (Right to Buy) | |
| Geoffrey A. Block | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 32,765 | 32,765 | - | - | Stock Option (Right to Buy) | |
| Onaiza Cadoret-Manier | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jun 2021 | 32,765 | 32,765 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jacobs | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jun 2021 | 7,500 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.29 per share. | 15 Jun 2021 | 7,500 | 124,051 (0%) | 0% | 7.3 | 54,659 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.54 per share. | 15 Jun 2021 | 7,500 | 131,551 (0%) | 0% | 0.5 | 4,050 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 7.22 per share. | 28 May 2021 | 3,062 | 26,750 (0%) | 0% | 7.2 | 22,098 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 612 | 40,678 (0%) | 0% | 7.1 | 4,338 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 2,534 | 214,754 (0%) | 0% | 7.1 | 17,960 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 612 | 159,435 (0%) | 0% | 7.1 | 4,338 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 157 | 29,812 (0%) | 0% | 7.1 | 1,113 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 721 | 124,051 (0%) | 0% | 7.1 | 5,110 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 508 | 102,912 (0%) | 0% | 7.1 | 3,601 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 611 | 45,303 (0%) | 0% | 7.1 | 4,331 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 7.09 per share. | 20 May 2021 | 612 | 106,954 (0%) | 0% | 7.1 | 4,338 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 06 Apr 2021 | 5,000 | 160,047 (0%) | 0% | 8 | 40,000 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 06 Apr 2021 | 1,826 | 107,566 (0%) | 0% | 8 | 14,608 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 8.00 per share. | 06 Apr 2021 | 3,337 | 109,392 (0%) | 0% | 8 | 26,696 | Common Stock |
| Muna Bhanji | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Mar 2021 | 63,687 | 63,687 | - | - | Stock Option (Right to Buy) | |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 608 | 41,290 (0%) | 0% | 6.9 | 4,185 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 2,534 | 217,288 (0%) | 0% | 6.9 | 17,440 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 193 | 29,969 (0%) | 0% | 6.9 | 1,328 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 612 | 165,047 (0%) | 0% | 6.9 | 4,212 | Common Stock |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 702 | 124,772 (0%) | 0% | 6.9 | 4,832 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 504 | 103,420 (0%) | 0% | 6.9 | 3,469 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 611 | 45,914 (0%) | 0% | 6.9 | 4,205 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 22 Feb 2021 | 593 | 112,729 (0%) | 0% | 6.9 | 4,081 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 146,755 | 146,755 | - | - | Stock Option (Right to Buy) | |
| Justin A. Renz | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 32,612 | 41,898 (0%) | 0% | 0 | Common Stock | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 517,959 | 517,959 | - | - | Stock Option (Right to Buy) | |
| Michael G. Raab | Director, President & CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 115,102 | 219,822 (0%) | 0% | 0 | Common Stock | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 146,755 | 146,755 | - | - | Stock Option (Right to Buy) | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 8,500 | 30,162 (0%) | 0% | 0 | Common Stock | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 32,612 | 165,659 (0%) | 0% | 0 | Common Stock | |
| David P. Rosenbaum | Chief Development Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 37,500 | 37,500 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jacobs | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 32,612 | 125,474 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Jacobs | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 146,755 | 146,755 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Gift of securities by or to the insider at price $ 0.00 per share. | 05 Jan 2021 | 405 | 71,717 (0%) | 0% | 0 | Common Stock | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 32,612 | 103,924 (0%) | 0% | 0 | Common Stock | |
| Elizabeth Grammer | See Remarks | Gift of securities by or to the insider at price $ 0.00 per share. | 05 Jan 2021 | 405 | 2,971 (0%) | 0% | 0 | Common Stock | |
| Elizabeth Grammer | See Remarks | Gift of securities by or to the insider at price $ 0.00 per share. | 05 Jan 2021 | 405 | 72,122 (0%) | 0% | 0 | Common Stock | |
| Elizabeth Grammer | See Remarks | Gift of securities by or to the insider at price $ 0.00 per share. | 05 Jan 2021 | 405 | 71,312 (0%) | 0% | 0 | Common Stock | |
| Elizabeth Grammer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 146,755 | 146,755 | - | - | Stock Option (Right to Buy) | |
| Susan Rodriguez | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 146,755 | 146,755 | - | - | Stock Option (Right to Buy) | |
| Susan Rodriguez | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 32,612 | 46,525 (0%) | 0% | 0 | Common Stock | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 146,755 | 146,755 | - | - | Stock Option (Right to Buy) | |
| Robert Blanks | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jan 2021 | 32,612 | 113,322 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Jacobs | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 6.88 per share. | 21 Dec 2020 | 3,949 | 92,862 (0%) | 0% | 6.9 | 27,153 | Common Stock |
| William C. Bertrand | Director | Grant, award, or other acquisition of securities at price $ 7.08 per share. | 14 Dec 2020 | 15,000 | 74,658 (0%) | 0% | 7.1 | 106,256 | Common Stock |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2020 | 41,000 | 78,000 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2020 | 1,000 | 119,000 | - | - | Stock Option (Right to Buy) | |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 7.30 per share. | 11 Dec 2020 | 41,000 | 72,527 (0%) | 0% | 7.3 | 299,300 | Common Stock |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.32 per share. | 11 Dec 2020 | 41,000 | 113,527 (0%) | 0% | 2.3 | 95,120 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 7.30 per share. | 11 Dec 2020 | 1,000 | 72,527 (0%) | 0% | 7.3 | 7,300 | Common Stock |
| Elizabeth Grammer | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.32 per share. | 11 Dec 2020 | 1,000 | 73,527 (0%) | 0% | 2.3 | 2,320 | Common Stock |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 5.89 per share. | 10 Dec 2020 | 170,000 | 417,284 (0%) | 0% | 5.9 | 1,000,841 | Common Stock |
| Susan Rodriguez | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 6.11 per share. | 16 Sep 2020 | 6,087 | 13,913 (0%) | 0% | 6.1 | 37,164 | Common Stock |
| Justin A. Renz | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.49 per share. | 15 Sep 2020 | 3,714 | 9,286 (0%) | 0% | 5.5 | 20,373 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 5.61 per share. | 15 Sep 2020 | 106,337 | 104,720 (0%) | 0% | 5.6 | 596,285 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.52 per share. | 15 Sep 2020 | 34,656 | 133,047 (0%) | 0% | 5.5 | 191,301 | Common Stock |
| David P. Rosenbaum | Chief Development Officer | Sale of securities on an exchange or to another person at price $ 5.51 per share. | 15 Sep 2020 | 3,470 | 21,662 (0%) | 0% | 5.5 | 19,131 | Common Stock |
| Jeffrey Jacobs | SVP, Technical Operations | Sale of securities on an exchange or to another person at price $ 5.53 per share. | 15 Sep 2020 | 40,804 | 106,811 (0%) | 0% | 5.5 | 225,589 | Common Stock |
| Jeffrey Jacobs | SVP, Technical Operations | Sale of securities on an exchange or to another person at price $ 6.05 per share. | 15 Sep 2020 | 10,000 | 96,811 (0%) | 0% | 6.1 | 60,500 | Common Stock |
| Elizabeth Grammer | See Remarks | Sale of securities on an exchange or to another person at price $ 5.37 per share. | 15 Sep 2020 | 28,810 | 72,527 (0%) | 0% | 5.4 | 154,574 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 5.45 per share. | 15 Sep 2020 | 34,685 | 80,710 (0%) | 0% | 5.5 | 189,182 | Common Stock |
| Robert Blanks | See Remarks | Sale of securities on an exchange or to another person at price $ 5.58 per share. | 01 Sep 2020 | 2,049 | 115,395 (0%) | 0% | 5.6 | 11,425 | Common Stock |
| Michael G. Raab | Director, President & CEO | Sale of securities on an exchange or to another person at price $ 7.01 per share. | 02 Jul 2020 | 23,128 | 24,364 (0%) | 0% | 7.0 | 162,130 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Jul 2020 | 14,258 | 0 (0%) | 0% | 0 | Common Stock | |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 6.96 per share. | 24 Jun 2020 | 68,373 | 247,284 (0%) | 0% | 7.0 | 476,040 | Common Stock |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 6.75 per share. | 24 Jun 2020 | 72,598 | 178,911 (0%) | 0% | 6.7 | 489,862 | Common Stock |
| David M. Mott | Director | Purchase of securities on an exchange or from another person at price $ 6.75 per share. | 22 Jun 2020 | 4,673 | 106,313 (0%) | 0% | 6.7 | 31,525 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.37 per share. | 15 Jun 2020 | 43 | 0 (0%) | 0% | 6.4 | 274 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.37 per share. | 15 Jun 2020 | 43 | 0 (0%) | 0% | 6.4 | 274 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 8,094 | 8,094 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 1,482,809 | 8,086,401 (12%) | 2% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 455,222 | 455,222 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 455,222 | 0 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 477,604 | 2,604,582 (3%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 7,164 | 7,164 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 7,164 | 0 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 539,587 | 2,942,599 (4%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 8,094 | 0 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 83,237 | 83,237 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 43 | 83,280 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 3,369 | 86,649 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 3,377 | 90,026 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 13,305 | 13,305 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 294 | 13,599 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 659 | 14,258 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 47 | 47 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 47 | 47 (0%) | 0% | 0 | Common Stock | |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.32 per share. | 10 Jun 2020 | 44,991 | 45,035 (0%) | 0% | 6.3 | 284,465 | Common Stock |
| Sandell D Scott | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.42 per share. | 10 Jun 2020 | 44,992 | 43 (0%) | 0% | 6.4 | 288,682 | Common Stock |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 389 | 389 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 7,164 | 7,164 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 7,164 | 0 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 539,587 | 2,942,599 (4%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 8,094 | 8,094 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 8,094 | 0 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 83,237 | 83,237 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 43 | 83,280 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 3,369 | 86,649 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 3,377 | 90,026 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 21,821 | 21,821 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.42 per share. | 10 Jun 2020 | 44,992 | 43 (0%) | 0% | 6.4 | 288,682 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 10 Jun 2020 | 1,079 | 0 (0%) | 0% | 6.4 | 6,880 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.37 per share. | 10 Jun 2020 | 21,821 | 0 (0%) | 0% | 6.4 | 138,989 | Common Stock |
| Forest Baskett | Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.32 per share. | 10 Jun 2020 | 44,991 | 45,035 (0%) | 0% | 6.3 | 284,465 | Common Stock |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 690 | 1,079 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 1,482,809 | 8,086,401 (12%) | 2% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 455,222 | 455,222 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 455,222 | 0 (0%) | 0% | 0 | Common Stock | |
| Forest Baskett | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 477,604 | 2,604,582 (3%) | 0% | 0 | Common Stock | |
| Michael G. Raab | Director, President & CEO | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 1,235 | 47,492 (0%) | 0% | 0 | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 10,825 | 11,066 (0%) | 0% | 0 | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 121 | 11,187 (0%) | 0% | 0 | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 137 | 11,324 (0%) | 0% | 0 | Common Stock | |
| Patrick J. Kerins | Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 10 Jun 2020 | 1,482,809 | 8,086,401 (12%) | 2% | 0 | Common Stock |