Historical shareholding details of State Street Russell Small Cap® Index holdings in Upstream Bio Inc. (UPB)

Monthly changes of State Street Russell Small Cap® Index shareholding in Upstream Bio Inc. over the previous months

Month	Name	Total no. shares held	Percent Holding
Month	Name	Total no. shares held	Percent Holding
Feb 28, 2025	State Street Russell Small Cap® Index	55,900	0.10%

Jan 31, 2025	State Street Russell Small Cap® Index	55,900	0.10%

Dec 31, 2024	State Street Russell Small Cap® Index	55,900	0.10%