Historical shareholding details of Two Sigma Investments LLC holdings in Spyre Therapeutics Inc. (SYRE)

Monthly changes of Two Sigma Investments LLC shareholding in Spyre Therapeutics Inc. over the previous months

Month	Name	Total no. shares held	Percent Holding
Month	Name	Total no. shares held	Percent Holding
Dec 31, 2024	Two Sigma Investments Llc	9,638	0.02%

Sep 30, 2024	Two Sigma Investments Llc	9,803	0.02%

Jun 30, 2024	Two Sigma Investments Llc	9,842	0.02%

Mar 31, 2024	Two Sigma Investments Llc	13,355	0.03%